Compounds > deferoxamine

deferoxamine and simvastatin

deferoxamine has been researched along with simvastatin in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's4 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Chen, SS; Chen, YC; Hsieh, CH; Hsieh, MW; Jeng, SF; Lu, TH; Rau, CS2

Reviews

1 review(s) available for deferoxamine and simvastatin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

5 other study(ies) available for deferoxamine and simvastatin

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Simvastatin-induced heme oxygenase-1 increases apoptosis of Neuro 2A cells in response to glucose deprivation.
    Toxicological sciences : an official journal of the Society of Toxicology, 2008, Volume: 101, Issue:1

    Topics: Animals; Apoptosis; Blotting, Western; Caspase 3; Cell Line; Cell Survival; Deferoxamine; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Flow Cytometry; Glucose; Heme Oxygenase-1; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Iron Chelating Agents; Mice; Neurons; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Protoporphyrins; RNA, Messenger; Simvastatin; Up-Regulation

2008
Statin-induced heme oxygenase-1 increases NF-kappaB activation and oxygen radical production in cultured neuronal cells exposed to lipopolysaccharide.
    Toxicological sciences : an official journal of the Society of Toxicology, 2008, Volume: 102, Issue:1

    Topics: Active Transport, Cell Nucleus; Animals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Deferoxamine; Enzyme Induction; Enzyme Inhibitors; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hydroxymethylglutaryl-CoA Reductase Inhibitors; I-kappa B Proteins; Iron; Iron Chelating Agents; Lipopolysaccharides; Membrane Proteins; Mice; NADP; Neurons; NF-kappa B; Phosphorylation; Protoporphyrins; Rats; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Simvastatin; Transcription Factor RelA

2008