deferoxamine and phenobarbital

deferoxamine has been researched along with phenobarbital in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19909 (50.00)18.7374
1990's3 (16.67)18.2507
2000's2 (11.11)29.6817
2010's4 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Glen, RC; Lowe, R; Mitchell, JB1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Granick, S; Sinclair, PR1
Hobara, T; Ishiyama, H; Kanbe, T; Ogino, K; Shimomura, Y1
Heger, B; Siegers, CP; Wilhelm, KP; Younes, M1
Farber, JL; Kyle, ME; Nakae, D; Serroni, A1
Siegers, CP; Younes, M1
Goulding, R1
Cederbaum, AI; Krikun, G1
Carnes, BA; Cerny, EA; Lau, EH; Rahman, YE1
Canavese, C; Luda, E; Rocca, G1
Brooker, JD; Elliott, WH; Lim, LK; May, BK; Srivastava, G1
Bonkovsky, HL; Donohue, S; Gildemeister, OS; Hahn, M; Krauss, GL; Lambrecht, RW; Pepe, JA1
Hirsch-Ernst, KI; Jungermann, K; Kahl, GF; Kietzmann, T1
Archakov, AI; Karuzina, II; Lisitsa, AV; Petushkova, NA; Zgoda, VG1
Enwere, G1

Reviews

2 review(s) available for deferoxamine and phenobarbital

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
A review of the quality of randomized clinical trials of adjunctive therapy for the treatment of cerebral malaria.
    Tropical medicine & international health : TM & IH, 2005, Volume: 10, Issue:11

    Topics: Anticonvulsants; Deferoxamine; Dexamethasone; Double-Blind Method; Enzyme Inhibitors; Humans; Malaria, Cerebral; Pentoxifylline; Phenobarbital; Randomized Controlled Trials as Topic; Sample Size; Siderophores; Tumor Necrosis Factor-alpha

2005

Other Studies

16 other study(ies) available for deferoxamine and phenobarbital

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Heme control on the synthesis of delta-aminolevulinic acid synthetase in cultured chick embryo liver cells.
    Annals of the New York Academy of Sciences, 1975, Apr-15, Volume: 244

    Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Cells, Cultured; Chick Embryo; Deferoxamine; Enzyme Induction; Heme; Hemin; Kinetics; Lead; Levulinic Acids; Liver; Phenobarbital; Protein Biosynthesis; Transcription, Genetic

1975
Hepatotoxicity of diethyldithiocarbamate in rats.
    Pharmacology & toxicology, 1990, Volume: 67, Issue:5

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Catalase; Deferoxamine; Ditiocarb; Glutathione; Injections, Subcutaneous; Liver; Liver Circulation; Male; Necrosis; Phenobarbital; Piperonyl Butoxide; Rats; Rats, Inbred Strains; Superoxide Dismutase; Thiobarbiturates

1990
Enhanced in vivo-lipid peroxidation associated with halothane hepatotoxicity in rats.
    Pharmacology & toxicology, 1988, Volume: 63, Issue:1

    Topics: Animals; Catechin; Deferoxamine; Ditiocarb; Glutathione; Halothane; Lipid Peroxides; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains

1988
1,3-(2-Chloroethyl)-1-nitrosourea potentiates the toxicity of acetaminophen both in the phenobarbital-induced rat and in hepatocytes cultured from such animals.
    Molecular pharmacology, 1988, Volume: 34, Issue:4

    Topics: Acetaminophen; Acetone; Carmustine; Cell Survival; Deferoxamine; Drug Synergism; Enzyme Induction; Glutathione; Liver; Male; Maleates; Methylcholanthrene; Phenobarbital; Phenylenediamines

1988
The role of iron in the paracetamol- and CCl4-induced lipid peroxidation and hepatotoxicity.
    Chemico-biological interactions, 1985, Volume: 55, Issue:3

    Topics: Acetaminophen; Animals; Breath Tests; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Deferoxamine; Enzyme Induction; Ethane; Iron; Lipid Peroxides; Male; Mice; Phenobarbital; Rats; Rats, Inbred Strains

1985
The treatment of acute poisoning.
    Transactions of the Medical Society of London, 1967, Volume: 83

    Topics: Acute Disease; Antidotes; Atropine; Barbiturates; Carbon Monoxide Poisoning; Chlorpromazine; Deferoxamine; England; Gastric Lavage; Heart Massage; Humans; Meperidine; Morphine; Oxygen; Paraldehyde; Phenobarbital; Poisoning; Salicylates; Suicide; Wales

1967
Stereochemical studies on the cytochrome P-450 and hydroxyl radical dependent pathways of 2-butanol oxidation by microsomes from chow-fed, phenobarbital-treated, and ethanol-treated rats.
    Biochemistry, 1984, Nov-06, Volume: 23, Issue:23

    Topics: Animals; Butanols; Cytochrome P-450 Enzyme System; Deferoxamine; Ethanol; Free Radicals; Hydroxides; Hydroxyl Radical; Kinetics; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Phenobarbital; Rats; Rats, Inbred Strains; Stereoisomerism

1984
Enhanced iron removal from liver parenchymal cells in experimental iron overload: liposome encapsulation of HBED and phenobarbital administration.
    Blood, 1983, Volume: 62, Issue:1

    Topics: Animals; Deferoxamine; Edetic Acid; Feces; Ferritins; Iron; Liposomes; Liver; Mice; Phenobarbital

1983
The EEG in progressive dialysis encephalopathy. The EEG and clinical indices of PDE in cases treated with desferrioxamine. (Part. II).
    Italian journal of neurological sciences, 1984, Volume: 5, Issue:4

    Topics: Aluminum; Brain Diseases; Deferoxamine; Electroencephalography; Humans; Middle Aged; Neuropsychological Tests; Phenobarbital; Renal Dialysis

1984
Evidence that in chick embryos destruction of hepatic microsomal cytochrome P-450 haem is a general mechanism of induction of delta-aminolaevulinate synthase by porphyria-causing drugs.
    The Biochemical journal, 1980, Sep-15, Volume: 190, Issue:3

    Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Chick Embryo; Cytochrome P-450 Enzyme System; Deferoxamine; Dicarbethoxydihydrocollidine; Enzyme Induction; Heme; Hemin; Microsomes, Liver; Phenobarbital; Porphyrias; Proadifen

1980
Effects of new anticonvulsant medications on porphyrin synthesis in cultured liver cells: potential implications for patients with acute porphyria.
    Neurology, 1997, Volume: 49, Issue:1

    Topics: Animals; Cells, Cultured; Chick Embryo; Deferoxamine; Dose-Response Relationship, Drug; Liver; Phenobarbital; Porphyrias; Porphyrins

1997
Mimicry in primary rat hepatocyte cultures of the in vivo perivenous induction by phenobarbital of cytochrome P-450 2B1 mRNA: role of epidermal growth factor and perivenous oxygen tension.
    Molecular pharmacology, 1999, Volume: 56, Issue:1

    Topics: Animals; Arteries; Cell Membrane; Chelating Agents; Cobalt; Cytochrome P-450 CYP2B1; Deferoxamine; Enzyme Induction; Enzyme Repression; Epidermal Growth Factor; ErbB Receptors; Gene Expression Regulation, Enzymologic; Growth Hormone; Heme; In Vitro Techniques; Liver; Male; Molecular Mimicry; Oxygen; Phenobarbital; Rats; Rats, Wistar; RNA, Messenger; Thyroxine

1999
Production of carbon monoxide by cytochrome P450 during iron-dependent lipid peroxidation.
    Toxicology in vitro : an international journal published in association with BIBRA, 2002, Volume: 16, Issue:1

    Topics: alpha-Tocopherol; Animals; Aryl Hydrocarbon Hydroxylases; Carbon Monoxide; Cytochrome P-450 Enzyme System; Deferoxamine; Enzyme Induction; Enzyme Inhibitors; Heme Oxygenase (Decyclizing); In Vitro Techniques; Iron; Lipid Peroxidation; Metyrapone; Microsomes, Liver; Phenobarbital; Proadifen; Protoporphyrins; Rabbits; Steroid Hydroxylases

2002