deferoxamine and penicillamine

deferoxamine has been researched along with penicillamine in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-199016 (40.00)18.7374
1990's11 (27.50)18.2507
2000's7 (17.50)29.6817
2010's5 (12.50)24.3611
2020's1 (2.50)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Hornbostel, H; Kaufmann, W; Siegenthaler, W1
Jones, MM; Pratt, TH1
Gachályi, A; Naményi, J; Szegedi, I; Varga, PL2
Meredith, TJ; Vale, JA1
Gachályi, A; Naményi, J; Szegedi, I; Varga, LP1
Aaseth, J1
van Oye, R1
Klimmer, OR1
Wirth, W1
Chisolm, JJ1
Eyring, EJ; Vig, BK1
Lange, J1
Halstead, BW; Williams, DR1
Lamarque, D; Whittle, BJ1
Bondy, SC; Naderi, S1
Liu, LL; Zhao, BL1
Behrman, HR; Musicki, B1
Ciuffi, M; Franchi-Micheli, S; Mugnai, S; Tarlini, L; Zilletti, L1
Philipov, P1
Chiueh, CC; Khaldi, A; Mohanakumar, KP; Rauhala, P1
Fukuyama, N; Genka, C; Ishida, H; Nakazawa, H; Su, Z; Todorov, R1
Richardson, DR; Wardrop, SL1
Arif, AJ; Chandra, S; Panday, V; Singh, C; Srivastava, PJ1
Kim, S; Ponka, P1
Nieland, LJ; Ramaekers, FC; Reutelingsperger, CP; Schutte, B; Steinbusch, HW; Terwel, D1
Lin, AM1
Hooper, NM; Lee, HB; Park, HS; Park, SW; Yoon, HJ1
Richardson, DR; Watts, RN1
MIKOL, C; RENOUX, M1
Chen, G; Pantopoulos, K; Wang, J1
Lui, EM; Suntres, ZE1
Bartosz, G; Lewinska, A1
Aaseth, J; Andersen, O; Cao, Y; Skaug, MA1
Filipský, T; Hašková, P; Holečková, M; Homola, P; Martin, J; Mladěnka, P; Palicka, V; Říha, M; Šimůnek, T; Váňová, K; Vávrová, J; Vítek, L1
Cilliers, K1

Reviews

6 review(s) available for deferoxamine and penicillamine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Therapeutic chelating agents.
    Journal of chemical education, 1976, Volume: 53, Issue:6

    Topics: Chelating Agents; Deferoxamine; Dimercaprol; Edetic Acid; Humans; Metallothionein; Metals; Penicillamine; Poisoning; Unithiol

1976
Antidotal therapy: pharmacokinetic aspects.
    Developments in toxicology and environmental science, 1986, Volume: 12

    Topics: Administration, Oral; Antidotes; Deferoxamine; Dimercaprol; Hot Temperature; Humans; Injections, Intramuscular; Kinetics; Naloxone; Penicillamine; Physical Exertion; Poisoning; Pralidoxime Compounds; Thiamine

1986
Chelating agents in medicine.
    Journal of toxicology. Clinical toxicology, 1982, Volume: 19, Issue:10

    Topics: Aluminum; Cadmium; Chelating Agents; Chromium; Copper; Deferoxamine; Dimercaprol; Edetic Acid; Environmental Pollutants; Humans; Iron; Mercury; Metals; Molybdenum; Penicillamine; Plutonium; Unithiol

1982
Chelation in metal intoxication--Principles and paradigms.
    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2015, Volume: 31

    Topics: Administration, Oral; Antidotes; Benzoates; Chelating Agents; Deferasirox; Deferiprone; Deferoxamine; Heavy Metal Poisoning; Humans; Penicillamine; Poisoning; Pyridones; Succimer; Triazoles; Trientine; Unithiol

2015
Trace element alterations in Alzheimer's disease: A review.
    Clinical anatomy (New York, N.Y.), 2021, Volume: 34, Issue:5

    Topics: Alzheimer Disease; Clioquinol; Copper; Deferoxamine; Humans; Metals; Penicillamine; Siderophores; Trace Elements

2021

Other Studies

34 other study(ies) available for deferoxamine and penicillamine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
[Therapy of poisoning with heavy metals].
    Deutsche medizinische Wochenschrift (1946), 1975, Apr-25, Volume: 100, Issue:17

    Topics: Aminolevulinic Acid; Cadmium Poisoning; Chromium; Deferoxamine; Dimercaprol; Edetic Acid; Ferrocyanides; Humans; Infusions, Parenteral; Iron; Lead Poisoning; Manganese Poisoning; Mercury Poisoning; Occupational Medicine; Penicillamine; Pentetic Acid; Thallium

1975
Effect of mixed ligand complex therapy on the retention of 95Nb and 144Ce in mice.
    Radiation research, 1989, Volume: 120, Issue:1

    Topics: Animals; Cerium Radioisotopes; Chelating Agents; Decontamination; Deferoxamine; Drug Therapy, Combination; Male; Mice; Niobium; Penicillamine; Pentetic Acid; Radioisotopes

1989
Modification of 144Ce tissue deposition by mixed ligand complex treatment in mice.
    Acta physiologica Hungarica, 1986, Volume: 68, Issue:3-4

    Topics: Animals; Body Burden; Cesium Radioisotopes; Chelating Agents; Deferoxamine; Drug Therapy, Combination; Injections, Intraperitoneal; Male; Mice; Mice, Inbred Strains; Penicillamine; Pentetic Acid; Salicylates; Salicylic Acid; Tissue Distribution

1986
Influence of mixed-ligand complexes on retention and distribution of radioniobium in mice.
    Radiation research, 1987, Volume: 112, Issue:2

    Topics: Animals; beta-Aminoethyl Isothiourea; Chelating Agents; Decontamination; Deferoxamine; Drug Therapy, Combination; Male; Mice; Niobium; Penicillamine; Pentetic Acid; Radioisotopes; Sodium Salicylate

1987
Chelating agents in medicine.
    British medical journal, 1971, May-01, Volume: 2, Issue:5756

    Topics: Chelating Agents; Chemistry, Pharmaceutical; Deferoxamine; Dicumarol; Edetic Acid; Hemochromatosis; Hepatolenticular Degeneration; Humans; Lead Poisoning; Penicillamine

1971
[Recent advance in the therapy of metal poisoning with complexing agents].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1972, May-10, Volume: 12, Issue:13

    Topics: Arsenic Poisoning; Carbon Isotopes; Chelating Agents; Deferoxamine; Dimercaprol; Edetic Acid; Humans; Iron; Lead Poisoning; Mercury Poisoning; Metals; Penicillamine; Pentetic Acid; Poisoning

1972
[Harmful effects of common drugs on the visual apparatus. The oligo-elements and chelating agents. B. Chelating agents].
    Bulletin de la Societe belge d'ophtalmologie, 1972, Volume: 160, Issue:1

    Topics: Chelating Agents; Deferoxamine; Dimercaprol; Edetic Acid; Eye Diseases; Humans; Penicillamine; Vision Disorders

1972
[Heavy metal antidotes].
    Archiv fur Toxikologie, 1968, Volume: 24, Issue:1

    Topics: Antidotes; Chelating Agents; Deferoxamine; Dimercaprol; Edetic Acid; Penicillamine; Pentetic Acid; Thallium; Thiocarbamates

1968
[Possible side-effects of antidotal therapy].
    Archiv fur Toxikologie, 1968, Volume: 24, Issue:1

    Topics: Antidotes; Atropine; Chelating Agents; Cyanides; Deferoxamine; Dimercaprol; Edetic Acid; Humans; Hydroxocobalamin; Metals; Nitrites; Penicillamine; Pentetic Acid; Phenols; Phosphates; Poisoning; Pralidoxime Compounds; Thiosulfates

1968
Poisoning due to heavy metals.
    Pediatric clinics of North America, 1970, Volume: 17, Issue:3

    Topics: Arsenic Poisoning; Cadmium Poisoning; Chelating Agents; Child; Child, Preschool; Copper; Deferoxamine; Dimercaprol; Edetic Acid; Gold; Humans; Infant; Iron; Lead Poisoning; Mercury Poisoning; Metals; Paint; Penicillamine; Pica; Poisoning; Thallium

1970
Absence of chromosome aberrations in cultured human leukocytes treated by two metal chelators--deferoxamine and penicillamine.
    Mutation research, 1971, Volume: 12, Issue:2

    Topics: Chromosome Aberrations; Deferoxamine; DNA; Humans; Leukocytes; Mitosis; Penicillamine

1971
[Chemica damage to the eye in industrial medicine].
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1969, Volume: 1-3, Issue:1

    Topics: Argyria; Burns, Chemical; Caustics; Chelating Agents; Chronic Disease; Copper; Deferoxamine; Dimercaprol; Eye Burns; Eye Diseases; Eye Foreign Bodies; Humans; Lead Poisoning; Mercury Poisoning; Occupational Diseases; Penicillamine; Pentetic Acid; Siderosis

1969
Role of oxygen-derived metabolites in the rat gastric mucosal injury induced by nitric oxide donors.
    European journal of pharmacology, 1995, Apr-24, Volume: 277, Issue:2-3

    Topics: Animals; Blood Pressure; Catalase; Deferoxamine; Disease Models, Animal; Drug Overdose; Drug Synergism; Endothelins; Free Radical Scavengers; Gastric Mucosa; Infusions, Intra-Arterial; Infusions, Intravenous; Male; Nitrates; Nitric Oxide; Nitroprusside; Penicillamine; Rats; Rats, Wistar; Reactive Oxygen Species; S-Nitroso-N-Acetylpenicillamine; Stomach Ulcer; Superoxide Dismutase; Thiourea; Vasodilator Agents

1995
The formation of reactive oxygen species in a fraction of rat brain by metabolism of nitric oxide.
    Neuroscience letters, 1994, Feb-28, Volume: 168, Issue:1-2

    Topics: Animals; Catalase; Cerebral Cortex; Deferoxamine; Ethanol; Kinetics; Male; Mannitol; Nitric Oxide; Nitroprusside; Penicillamine; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase; Synaptosomes; Vasodilator Agents

1994
[A study on the protective effect of metallic chelators on ischemia-reperfusion injury of isolated rat heart].
    Zhonghua xin xue guan bing za zhi, 1993, Volume: 21, Issue:5

    Topics: Animals; Creatine Kinase; Deferoxamine; Female; Free Radical Scavengers; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Penicillamine; Rats; Rats, Wistar

1993
Metal chelators reverse the action of hydrogen peroxide in rat luteal cells.
    Molecular and cellular endocrinology, 1993, Volume: 92, Issue:2

    Topics: Animals; Cell Membrane Permeability; Cells, Cultured; Chelating Agents; Corpus Luteum; Cyclic AMP; Deferoxamine; Ethylenediamines; Female; Free Radical Scavengers; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Luteinizing Hormone; Penicillamine; Phenanthrolines; Progesterone; Rats; Rats, Inbred Strains; Receptors, LH; Signal Transduction

1993
Hemoglobin affects lipid peroxidation and prostaglandin E2 formation in rat corticocerebral tissues in vitro.
    Biochemical pharmacology, 1996, Jul-12, Volume: 52, Issue:1

    Topics: Animals; Cerebral Cortex; Cyclooxygenase Inhibitors; Deferoxamine; Dinoprostone; Free Radical Scavengers; Hemoglobins; In Vitro Techniques; Indomethacin; Iron Chelating Agents; Lipid Peroxidation; Male; Penicillamine; Rats; Rats, Wistar; Vitamin E

1996
Suppression of tumor growth in experimental 9L gliosarcoma model by copper depletion.
    Neurologia medico-chirurgica, 1996, Volume: 36, Issue:2

    Topics: Brain Neoplasms; Chelating Agents; Deferoxamine; Glioma; Humans; Penicillamine; Trace Elements

1996
Apparent role of hydroxyl radicals in oxidative brain injury induced by sodium nitroprusside.
    Free radical biology & medicine, 1998, Volume: 24, Issue:7-8

    Topics: Animals; Ascorbic Acid; Brain Injuries; Deferoxamine; Hydrogen Peroxide; Hydroxyl Radical; In Vitro Techniques; Iron; Lipid Peroxidation; Male; Nerve Degeneration; Nitric Oxide; Nitroprusside; Oxidative Stress; Oxyhemoglobins; Penicillamine; Rats; Rats, Sprague-Dawley

1998
Peroxynitrite is not a major mediator of endothelial cell injury by activated neutrophils in vitro.
    Cardiovascular research, 1998, Volume: 39, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Cattle; CD18 Antigens; Cells, Cultured; Coculture Techniques; Deferoxamine; Dimethyl Sulfoxide; Endothelium, Vascular; Humans; Neutrophil Activation; Neutrophils; Nitrates; Nitric Oxide Synthase; Nitrites; Ornithine; Penicillamine; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tyrosine

1998
The effect of intracellular iron concentration and nitrogen monoxide on Nramp2 expression and non-transferrin-bound iron uptake.
    European journal of biochemistry, 1999, Volume: 263, Issue:1

    Topics: 3' Untranslated Regions; Animals; Base Sequence; Biological Transport, Active; Carrier Proteins; Cation Transport Proteins; Cell Line; Chelating Agents; Deferoxamine; DNA Primers; Ferric Compounds; Gene Expression; Intracellular Fluid; Iron; Iron-Binding Proteins; Iron-Regulatory Proteins; Iron-Sulfur Proteins; Kinetics; Membrane Proteins; Mice; Molecular Sequence Data; Nitric Oxide; Nitric Oxide Donors; Nucleic Acid Conformation; Penicillamine; Quaternary Ammonium Compounds; Receptors, Transferrin; RNA-Binding Proteins; RNA, Messenger; Transferrin

1999
Metal chelators/antioxidants: approaches to protect erythrocytic oxidative stress injury during Plasmodium berghei infection in Mastomys coucha.
    Pharmacological research, 1999, Volume: 40, Issue:3

    Topics: Animals; Antioxidants; Catechin; Chelating Agents; Deferoxamine; Erythrocytes; Glutathione; Lipid Peroxidation; Malaria; Male; Muridae; Oxidative Stress; Penicillamine; Plasmodium berghei; Superoxide Dismutase; Superoxides

1999
Control of transferrin receptor expression via nitric oxide-mediated modulation of iron-regulatory protein 2.
    The Journal of biological chemistry, 1999, Nov-12, Volume: 274, Issue:46

    Topics: Animals; Cell Line; Cysteine Endopeptidases; Deferoxamine; Ferric Compounds; Gene Expression Regulation; Iron; Iron Regulatory Protein 1; Iron Regulatory Protein 2; Iron-Regulatory Proteins; Iron-Sulfur Proteins; Macrophages; Mice; Multienzyme Complexes; Nitric Oxide; Nitroprusside; Penicillamine; Protease Inhibitors; Proteasome Endopeptidase Complex; Protein Binding; Proto-Oncogene Proteins; Quaternary Ammonium Compounds; Receptors, Transferrin; RNA-Binding Proteins; RNA, Messenger; Time Factors; Wnt2 Protein

1999
S-nitroso-N-acetylpenicillamine and nitroprusside induce apoptosis in a neuronal cell line by the production of different reactive molecules.
    European journal of pharmacology, 2000, Jul-14, Volume: 400, Issue:1

    Topics: 1-Methyl-4-phenylpyridinium; Apoptosis; Catalase; Deferoxamine; Flow Cytometry; Hydrogen Peroxide; Molsidomine; Neuroblastoma; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase; Tumor Cells, Cultured

2000
Coexistence of zinc and iron augmented oxidative injuries in the nigrostriatal dopaminergic system of SD rats.
    Free radical biology & medicine, 2001, Feb-01, Volume: 30, Issue:3

    Topics: Anesthesia; Animals; Brain; Corpus Striatum; Deferoxamine; Dopamine; Drug Interactions; Glutathione; Iron; Lipid Peroxidation; Male; Melatonin; Oxidative Stress; Parkinsonian Disorders; Penicillamine; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Spectrometry, Fluorescence; Substantia Nigra; Tyrosine 3-Monooxygenase; Zinc

2001
Nitric oxide inhibits the shedding of the glycosylphosphatidylinositol-anchored dipeptidase from porcine renal proximal tubules.
    The Biochemical journal, 2002, May-15, Volume: 364, Issue:Pt 1

    Topics: Animals; Arginine; Blotting, Western; Deferoxamine; Dithiothreitol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrenes; Glycosylphosphatidylinositols; Kidney; Kidney Tubules; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitroprusside; Penicillamine; Phosphodiesterase Inhibitors; Protein Binding; Pyrrolidinones; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Superoxide Dismutase; Swine; Time Factors; Type C Phospholipases

2002
The mechanism of nitrogen monoxide (NO)-mediated iron mobilization from cells. NO intercepts iron before incorporation into ferritin and indirectly mobilizes iron from ferritin in a glutathione-dependent manner.
    European journal of biochemistry, 2002, Volume: 269, Issue:14

    Topics: Adenocarcinoma; Animals; Breast Neoplasms; Cell Membrane Permeability; Cell-Free System; Cytosol; Deferoxamine; Female; Ferritins; Fibroblasts; Glutathione; Humans; Iron; Iron Chelating Agents; Macrophage Activation; Mice; Neuroblastoma; Neuroectodermal Tumors, Primitive, Peripheral; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Oxidation-Reduction; Penicillamine; S-Nitrosoglutathione; Spermine; Tumor Cells, Cultured

2002
[CHELATION].
    La Presse medicale, 1964, Dec-05, Volume: 72

    Topics: Chelating Agents; Deferoxamine; Drug Therapy; Edetic Acid; Humans; Iron; Penicillamine; Pharmacology; Toxicology

1964
Nitric oxide inhibits the degradation of IRP2.
    Molecular and cellular biology, 2005, Volume: 25, Issue:4

    Topics: Animals; Deferoxamine; Gene Expression Regulation, Neoplastic; Humans; Iron; Iron Regulatory Protein 2; Mice; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Penicillamine; Proteasome Endopeptidase Complex; Protein Denaturation; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2005
Prooxidative effect of copper--metallothionein in the acute cytotoxicity of hydrogen peroxide in Ehrlich ascites tumour cells.
    Toxicology, 2006, Jan-16, Volume: 217, Issue:2-3

    Topics: Animals; Calcium; Carcinoma, Ehrlich Tumor; Cell Survival; Copper; Copper Sulfate; Deferoxamine; Dose-Response Relationship, Drug; Glutathione Disulfide; Hydrogen Peroxide; Injections, Intraperitoneal; Iron; Lipid Peroxidation; Male; Mannitol; Metallothionein; Mice; Oxidative Stress; Penicillamine; Pinocytosis; Time Factors; Tumor Cells, Cultured; Zinc

2006
Yeast flavohemoglobin protects against nitrosative stress and controls ferric reductase activity.
    Redox report : communications in free radical research, 2006, Volume: 11, Issue:5

    Topics: Cell Division; Deferoxamine; Dioxygenases; Dose-Response Relationship, Drug; Ferricyanides; FMN Reductase; Gene Deletion; Hemeproteins; Hydrogen Peroxide; Mutation; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Oxidation-Reduction; Penicillamine; Peroxynitrous Acid; S-Nitrosoglutathione; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sodium Hypochlorite; Time Factors

2006
Protective Effects of D-Penicillamine on Catecholamine-Induced Myocardial Injury.
    Oxidative medicine and cellular longevity, 2016, Volume: 2016

    Topics: Animals; Cardiotonic Agents; Catecholamines; Cell Line; Cell Survival; Deferoxamine; Hydrogen-Ion Concentration; Ions; Iron; Iron Chelating Agents; Male; Myocardium; Penicillamine; Rats, Wistar; Troponin T

2016