Compounds > deferoxamine

deferoxamine and methotrexate

deferoxamine has been researched along with methotrexate in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19904 (36.36)18.7374
1990's0 (0.00)18.2507
2000's1 (9.09)29.6817
2010's6 (54.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Faller, B; Wohnsland, F1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Glen, RC; Lowe, R; Mitchell, JB1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Cohen, A; Estrov, Z; Freedman, MH; Gelfand, EW1
Firkin, B; Rother, M; Van der Weyden, M1
Carcassi, U1
Baldeschwieler, JD; Li, MP; Patel, KR; Schuh, JR1
Haskova, P; Jansova, H; Kalinowski, DS; Machacek, M; Potuckova, E; Richardson, DR; Richardson, V; Simunek, T; Tichotova, L; Vavrova, A1

Reviews

1 review(s) available for deferoxamine and methotrexate

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

10 other study(ies) available for deferoxamine and methotrexate

ArticleYear
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
    Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6

    Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water

2001
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Synergistic antiproliferative effects on HL-60 cells: deferoxamine enhances cytosine arabinoside, methotrexate, and daunorubicin cytotoxicity.
    The American journal of pediatric hematology/oncology, 1988,Winter, Volume: 10, Issue:4

    Topics: Antimetabolites, Antineoplastic; Cell Line; Cytarabine; Daunorubicin; Deferoxamine; Dose-Response Relationship, Drug; Drug Synergism; Humans; Leukemia, Promyelocytic, Acute; Methotrexate; Tumor Cells, Cultured

1988
Megaloblastic maturation masked by iron deficiency: a biochemical basis.
    British journal of haematology, 1972, Volume: 22, Issue:3

    Topics: Anemia, Hypochromic; Anemia, Macrocytic; Bone Marrow; Culture Techniques; Deferoxamine; Deoxyuridine; DNA; Folic Acid Deficiency; Humans; Iron; Methotrexate; Thymidine; Tritium; Vitamin B 12 Deficiency

1972
[Modern therapeutic possibilities in Cooley's disease].
    Atti della Accademia dei fisiocritici in Siena. Sezione medico-fisica, 1966, Volume: 15, Issue:2

    Topics: Adolescent; Antibody Formation; Azathioprine; Betamethasone; Blood Transfusion; Child; Child, Preschool; Deferoxamine; Drug Tolerance; Humans; Immune Tolerance; Infant; Methotrexate; Thalassemia

1966
The pharmacological efficacy of a rigid non-phospholipid liposome drug delivery system.
    Biochimica et biophysica acta, 1984, Jan-24, Volume: 797, Issue:1

    Topics: Animals; Cholesterol; Deferoxamine; Drug Stability; Liposomes; Liver Neoplasms, Experimental; Methotrexate; Mice; Mice, Inbred C3H; Microscopy, Electron; Sonication; Tissue Distribution

1984
Quantitative analysis of the anti-proliferative activity of combinations of selected iron-chelating agents and clinically used anti-neoplastic drugs.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Aldehydes; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Proliferation; Cyclophosphamide; Deferoxamine; Doxorubicin; Drug Synergism; Fluorouracil; Humans; Hydrazones; Iron Chelating Agents; MCF-7 Cells; Methotrexate; Paclitaxel; Tamoxifen; Thiosemicarbazones

2014