deferoxamine has been researched along with hydroxyl radical in 176 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 46 (26.14) | 18.7374 |
| 1990's | 92 (52.27) | 18.2507 |
| 2000's | 32 (18.18) | 29.6817 |
| 2010's | 6 (3.41) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Smith, LL; van Asbeck, BS; Van der Wal, NA; van Oirschot, JF | 1 |
| Ganesh, KN; Joshi, RR | 1 |
| Dalal, NS; Gannett, PM; Shi, XG; Sun, XL | 1 |
| Foerder, CA; Zager, RA | 1 |
| Ferrari, M; Forte, T; Menditto, A; Minetti, M; Quaresima, V; Soriani, M | 1 |
| Ashraf, M; Onodera, T; Takemura, G | 2 |
| Chobanian, MC; Julin, CM; Sundaram, V; Zimmerman, JJ | 1 |
| Kagan, VE; Khwaja, S; Packer, L; Ramsey, R; Reznick, AZ; Serbinova, EA; Tsuchiya, M | 1 |
| Das, DK; Lu, D; Lyengar, J; Maity, S; Russel, JC | 1 |
| Zager, RA | 1 |
| Ghio, AJ; Piantadosi, CA; Zhang, J | 1 |
| Aruoma, OI; Halliwell, B; Mitchinson, MJ; Smith, C | 1 |
| Abdallah, MA; Brissot, P; Cillard, J; Cillard, P; Lescoat, G; Morel, I; Ocaktan, AZ; Pasdeloup, N; Sergent, O | 1 |
| Bhuyan, DK; Bhuyan, KC; Chiu, W; Fridovich, I; Malik, S | 1 |
| Britigan, BE; Wilson, ME; Zarley, JH | 1 |
| Shah, SV; Walker, PD | 1 |
| Hebbel, RP; Repka, T | 1 |
| Bény, JL; von der Weid, PY | 1 |
| Hiraishi, H; Ivey, KJ; Mutoh, H; Ota, S; Razandi, M; Sugimoto, T; Terano, A | 1 |
| Freeman, D; Hollander, D; Krugliak, P; Ma, TY; Nguyen, T | 1 |
| Hahn, SM; Mitchell, JB; Pinson, A; Russo, A; Samuni, A; Winkelsberg, D | 1 |
| Floyd, RA; Gutteridge, JM; Maidt, L; Price, S; Schneider, JE | 1 |
| Martorana, GE; Meucci, E; Miggiano, GA; Mordente, A | 1 |
| Keyse, SM; Tyrrell, RM | 1 |
| van Asbeck, BS; van der Wal, NA; van Dijk, A; van Oirschot, JF; Verhoef, J | 1 |
| Berg, R; Bridges, W; Deitch, EA; Granger, DN; Specian, RD | 1 |
| Lloyd, RV; Mason, RP | 1 |
| Das, DK; George, A; Iyengar, J; Russell, JC | 1 |
| Henderson, JS; Singh, A; Singh, H | 1 |
| Costa, D; Fontecave, M; Jaouen, M; Mansuy, D; Pezerat, H; Zalma, R | 1 |
| Gross, GJ; Kalyanaraman, B; Pieper, GM | 1 |
| Gutteridge, JM | 1 |
| Barton, JC; Briggs, DD; Butler, TW; Chandler, DB; Fulmer, JD; Grizzle, WE | 1 |
| Blount, S; Griffiths, HR; Lunec, J | 1 |
| Hearse, DJ; Maxwell, MP; Yellon, DM | 1 |
| Vartio, T | 1 |
| Albano, A; Brandi, G; Cantoni, O; Cattabeni, F | 1 |
| Davison, AJ; Gee, P | 1 |
| Cochrane, CG; Dizdaroglu, M; Fuciarelli, AF; Gajewski, E; Hyslop, PA; Jackson, JH; Schraufstatter, IU | 1 |
| el-Alfy, MS; el-Baz, F; el-Kholy, M; Fakeir, AA; Khalifa, AS; Khazbak, MA; Mokhtar, G | 1 |
| Bacon, BR; Grisham, MB; Inauen, W; Kvietys, PR | 1 |
| Batist, G; Cowan, KH; Katki, AG; Myers, CE; Sinha, BK | 1 |
| Boyce, NW; Campbell, D; Holdsworth, SR | 1 |
| Gauduel, Y; Grousset, C; Menasche, P; Mouas, C; Piwnica, A | 1 |
| Fox, IH; Fudman, EJ; Till, GO | 1 |
| Gupta, M; Singal, PK | 1 |
| Awai, M; Ogino, T | 1 |
| Shah, SV | 1 |
| Lutz, MJ; Till, GO; Ward, PA | 1 |
| Albano, E; Dianzani, MU; Goria-Gatti, L; Tomasi, A | 1 |
| Cederbaum, AI; Puntarulo, S | 1 |
| Bernard, M; Cozzone, PJ; Grousset, C; Menasché, P; Piétri, S; Piwnica, A | 1 |
| Shah, SV; Thakur, V; Walker, PD | 1 |
| Hatherill, JR; Lutz, MJ; Till, GO; Tourtellotte, WW; Ward, PA | 1 |
| Cederbaum, AI; Krikun, G | 2 |
| Beloqui, O; Cederbaum, AI | 1 |
| Gutteridge, JM; Quinlan, GJ | 1 |
| Calabria, AA; Cavallo, G; Giordano, N; Lalumera, M; Marcolongo, R; Mazzullo, G; Morozzi, G | 1 |
| Borg, DC; Drew, RT; Osheroff, MR; Schaich, KM | 1 |
| Chevion, M; Katzhendler, J; Kohen, R; Korbashi, P | 1 |
| Fernandez, MA; Marak, GE; Rao, NA; Romero, JL; Sevanian, A | 1 |
| Anderson, DK; Eaton, JW; Hallaway, PE; Panter, SS; Sadrzadeh, SM | 1 |
| Boyce, NW; Holdsworth, SR | 1 |
| Nordmann, R; Ribière, C; Rouach, H | 1 |
| Borg, DC; Schaich, KM | 1 |
| Granger, DN; Grisham, MB; Hernandez, LA | 1 |
| Cederbaum, AI | 2 |
| Towell, JF; Wang, RI | 1 |
| Allan, IM; Bacon, PA; Lunec, J; Salmon, M | 1 |
| Aisen, P; Baldwin, DA; Jenny, ER | 1 |
| Carlin, G; Djursäter, R | 1 |
| Cederbaum, AI; Dicker, E | 1 |
| Graceffa, P; Weitzman, SA | 1 |
| Gutteridge, JM; Quinlan, GJ; Wilkins, S | 1 |
| Fitzsimmons, J; Guy, J; Mancuso, A; McGorray, S; Qi, X; Rao, N | 1 |
| Benedict, CR; Pakala, R | 1 |
| Batabyal, SK; Chakraborti, S; Chakraborti, T | 1 |
| Akiyama, T; Okada, S; Sarker, AH; Seki, S; Watanabe, S | 1 |
| Huang, HS; Longhurst, JC; Pan, HL; Stahl, GL | 1 |
| Dzwigaj, S; Pezerat, H | 1 |
| Hafström, L; Lindnér, P; Naredi, P; Peterson, A | 1 |
| Furuno, K; Suetsugu, T; Sugihara, N | 1 |
| Altman, SA; Dizdaroglu, M; Lumpkin, JA; Madurawe, R; Randers-Eichhorn, L; Rao, G; Zastawny, TH | 1 |
| Augusto, O; Denicola, A; Gatti, RM; Radi, R; Souza, JM | 1 |
| Clerici, WJ; DiMartino, DL; Prasad, MR | 1 |
| Burkitt, MJ; Kadiiska, MB; Mason, RP; Xiang, QH | 1 |
| Crapo, JD; Oury, TD; Piantadosi, CA | 1 |
| Guice, KS; Magee, JC; Myers, SI; Oldham, KT; Turnage, RH | 1 |
| Aubailly, M; Bazin, JC; Haigle, J; Mazière, JC; Salmon, S; Santus, R | 1 |
| Averbukh, E; Berenshtein, E; Kitrossky, N; Ophir, A | 1 |
| Franzini, E; Hakim, J; Pasquier, C; Sellak, H | 1 |
| Catravas, JD; Chen, X | 1 |
| Limm, W; McNamara, JJ; Premaratne, S; Suehiro, A; Suehiro, G; Watanabe, BI | 1 |
| Chagas, AC; da-Luz, PL; Laurindo, FR; Pileggi, F | 1 |
| Hamada, T | 1 |
| Ben-Shachar, D; Eshel, G; Finberg, JP; Riederer, P; Youdim, MB | 1 |
| Burkitt, MJ; Hanna, PM; Jordan, SJ; Kadiiska, MB; Mason, RP | 1 |
| Dalal, NS; Kasprzak, KS; Shi, X | 1 |
| Brunk, U; Roberg, K; Zdolsek, J; Zhang, H | 1 |
| Longhurst, JC; Pan, HL; Stahl, GL | 1 |
| Behrman, HR; Musicki, B | 1 |
| Bolli, R; Li, XY; McCay, PB; Sekili, S; Sun, JZ; Tang, L; Thornby, JI; Zughaib, M | 1 |
| Burkhart, KM; Conrad, DS; Gmur, DJ; Zager, RA | 1 |
| Jiang, JJ; Liu, KJ; Mao, Y; Shi, X | 1 |
| Demling, R; Ikegami, K; LaLonde, C | 1 |
| De Wit, LE; Gramsbergen, JB; Korf, J; Koster, JF; Sloot, WN | 1 |
| Kondo, T | 1 |
| Ong, CN; Shen, HM; Shen, Y; Shi, CY | 1 |
| Chakraborti, S; Chakraborti, T; Ghosh, JJ; Ghosh, SK; Kar, S; Roychoudhury, S | 1 |
| Andorn, AC; Bacon, BR; Britton, RS | 1 |
| Fu, LW; Halliwell, B; Longhurst, JC; O'Neill, CA | 1 |
| Babin-Chevaye, C; Franzini, E; Hakim, J; Marquetty, C; Pasquier, C; Sellak, H | 1 |
| Clerici, WJ; Yang, L | 1 |
| Hsu, TH; Kou, YR; Lai, CJ; Lin, YS | 1 |
| Asimakis, GK; Ethridge, RT; Inners, KF | 1 |
| Bandyopadhyay, D; Banerjee, RK; Bhattacharjee, M; Das, D | 1 |
| Dalal, NS; Liu, KJ; Shi, X | 1 |
| Jiang, DH; Lan, J | 1 |
| An, W; Corrales, FJ; Mato, JM; Mingorance, J; Ruiz, F; Sánchez-Góngora, E | 1 |
| De Leo, T; Di Meo, S; Piro, MC; Venditti, P | 1 |
| Beswick, PH; Brown, DM; Dineva, M; Donaldson, K; Gilmour, P; MacNee, W; Mitchell, C | 1 |
| Asad, NR; Furtado, FA; Leitão, AC | 1 |
| Chiueh, CC; Khaldi, A; Mohanakumar, KP; Rauhala, P | 1 |
| Agah, A; Collard, CD; Stahl, GL | 1 |
| Chaplin, DJ; Dennis, MF; Holder, AL; Parkins, CS; Stratford, MR | 1 |
| Armour, JA; Horackova, M; Thompson, GW | 1 |
| Acker, H; Jungermann, K; Kietzmann, T; Porwol, T; Zierold, K | 1 |
| Yamamoto, BK; Zhu, W | 1 |
| Benderitter, M; Briot, F; Dalloz, F; Maupoil, V; Rochette, L; Vergely, C | 1 |
| Kiyose, M; Lee, CI; Okabe, E | 1 |
| Barry, OP; FitzGerald, GA; Ghiselli, A; Iuliano, L; Pasin, M; Praticó, D; Sabatino, G; Violi, F | 1 |
| Jörns, A; Lenzen, S; Munday, R; Tiedge, M | 1 |
| Hallworth, R; Jarboe, JK | 1 |
| Boffi, FM; Inanami, O; Kuwabara, M; Matsuki, N; Ono, K; Takanohashi, A | 1 |
| Benson, EE; Bremner, DH; Day, JG; Fleck, RA | 1 |
| Borisenko, GG; Hsia, CJ; Kagan, VE; Schor, NF | 1 |
| Castranova, V; Leonard, S; Shi, X; Vallyathan, V; Wang, S; Zang, L | 1 |
| Furukawa, Y; Ishii, M; Kashimoto, T; Nishimura, Y; Sasaki, YF; Sugiyama, M; Susa, N; Ueda, J; Ueno, S; Yasuno, M; Yokoi, K | 1 |
| Mizuno, M; Olea-Azar, CA; Ozawa, T; Takeshita, K | 1 |
| Higo, A; Katsura, M; Mohri, Y; Ohkuma, S; Shirotani, K; Shuto, K; Takesue, M; Tarumi, C | 1 |
| González, C; Latorre, R; Lissi, E; Soto, MA; Vergara, C | 1 |
| Amati, M; Bolognini, L; Carmignani, M; Coloccini, S; Fenoglio, I; Fubini, B; Governa, M; Valentino, M; Volpe, AR | 1 |
| Bechtold, M; Frahry, G; Liszkay, A; Schopfer, P; Wagner, A | 1 |
| Lapatto, R; Martelin, E; Raivio, KO | 1 |
| Besse, S; Boucher, F; de Leiris, J; Tanguy, S | 1 |
| Gebicki, JM; Tweeddale, H | 1 |
| Brunk, UT; Eaton, JW; Persson, HL; Yu, Z | 1 |
| Brunk, UT; Eaton, JW; Persson, HL; Tirosh, O; Yu, Z | 1 |
| Aiken, BA; Edwards, JA; McLoughlin, TJ; Pizza, FX; Tsivitse, SK | 1 |
| Kang, JH | 1 |
| Wu, W; Yu, C; Zeng, Z | 1 |
| Hirooka, Y; Ito, K; Kimura, Y; Kishi, T; Shimokawa, H; Takeshita, A | 1 |
| Hirata, H; Ono, M; Takajo, T; Takeshita, K; Utsumi, H | 1 |
| Assi, LK; Craddock, RM; Lord, JM; Salmon, M; Scheel-Toellner, D; Wang, K; Webb, PR | 1 |
| Biswas, J; Manoharan, PT; Rajesh, M; Ramakrishnan, S; Sulochana, KN | 1 |
| Kato, H; Kawai, Y; Kubota, E; Lee, MC; Miyazaki, H; Shoji, H; Suga, M; Yoshino, F | 1 |
| Berenshtein, E; Chevion, M; Drenger, B; Elami, A; Gozal, Y; Kitrossky, N | 1 |
| Benson, EE; Bremner, DH; Millam, S; Obert, B; Pret'ová, A | 1 |
| Bizzozero, OA; Bolognani, F; De Jesus, G; Ziegler, JL | 1 |
| Obata, T | 1 |
| Ikeda, M; Kawamura, Y; Komatsu, T; Kubota, E; Lee, MC; Maehata, Y; Maetani, T; Miyagi, A; Shoji, H; Yoshino, F | 1 |
| Naus, J; Pospísil, P; Snyrychová, I | 1 |
| Chang, SY; Ho, CY; Kou, YR; Tsai, TL | 1 |
| Alaghmand, M; Blough, NV | 1 |
| Nakatani, N; Sakugawa, H; Shindo, H; Takeda, K; Ueda, M | 1 |
| Shan, GQ; Zhu, BZ | 1 |
| Cagnin, M; Castino, R; Fiorentino, I; Giovia, A; Isidoro, C | 1 |
| Lim, BS; Park, HC; Son, KM; Yang, HC; Zhu, T | 1 |
| Bester, J; Gericke, GS; Kell, DB; Lipinski, B; Pretorius, E; Vermeulen, N | 1 |
| Black, SM; Harris, VA; Kumar, S; Lu, Q; Rafikov, R; Sun, X | 1 |
| Iida, K; Nakayama, H; Shiota, S; Tamura, T; Yoshida, S; Yoshimura, M | 1 |
| Kohno, M; Niwano, Y; Tada, M | 1 |
4 review(s) available for deferoxamine and hydroxyl radical
| Article | Year |
|---|---|
Involvement of iron and iron-catalyzed free radical production in ethanol metabolism and toxicity.
Topics: Alcoholic Intoxication; Animals; Brain; Catalase; Deferoxamine; Ethanol; Free Radicals; Humans; Hydroxides; Hydroxyl Radical; Iron; Lipid Peroxides; Liver | 1987 |
Parkinson's disease and free radicals. Mechanism of neurodegeneration and neuroprotection.
Topics: Corpus Striatum; Deferoxamine; Free Radicals; Humans; Hydroxyl Radical; Nerve Degeneration; Neurons; Parkinson Disease | 1996 |
Desferrioxamine and vitamin E protect against iron and MPTP-induced neurodegeneration in mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Diseases; Corpus Striatum; Deferoxamine; Dopamine; Female; Glutathione; Glutathione Disulfide; Hydroxyl Radical; Iron; Lipid Peroxides; Male; Mice; Nerve Degeneration; Osmolar Concentration; Vitamin E | 1997 |
Clustering of death receptors in lipid rafts initiates neutrophil spontaneous apoptosis.
Topics: Animals; Apoptosis; Caspase 3; Caspase 8; Caspases; Ceramides; Deferoxamine; Enzyme Activation; fas Receptor; Glutathione; Hydroxyl Radical; Membrane Microdomains; Mice; Mice, Transgenic; Models, Biological; Neutrophils; Reactive Oxygen Species; Receptors, Tumor Necrosis Factor; Sphingomyelin Phosphodiesterase; Time Factors | 2004 |
2 trial(s) available for deferoxamine and hydroxyl radical
| Article | Year |
|---|---|
Effect of desferrioxamine B on hemolysis in glucose-6-phosphate dehydrogenase deficiency.
Topics: Child, Preschool; Deferoxamine; Female; Glucosephosphate Dehydrogenase Deficiency; Hemoglobins; Hemolysis; Humans; Hydroxides; Hydroxyl Radical; Infant; Male | 1989 |
Deferoxamine induced decreases of lipid peroxides in rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Deferoxamine; Double-Blind Method; Female; Ferritins; Humans; Hydroxides; Hydroxyl Radical; Injections, Intra-Articular; Lipid Peroxides; Male; Middle Aged; Synovial Fluid | 1987 |
170 other study(ies) available for deferoxamine and hydroxyl radical
| Article | Year |
|---|---|
Effect of iron chelators on paraquat toxicity in rats and alveolar type II cells.
Topics: Animals; Chelating Agents; Deferoxamine; Free Radical Scavengers; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Lung; Male; Paraquat; Pulmonary Alveoli; Rats; Rats, Inbred Strains | 1992 |
Chemical cleavage of plasmid DNA by Cu(II), Ni(II) and Co(III) desferal complexes.
Topics: Cobalt; Copper; Deferoxamine; DNA, Bacterial; Free Radical Scavengers; Free Radicals; Hydrolysis; Hydroxides; Hydroxyl Radical; Nickel; Plasmids | 1992 |
Deferoxamine inhibition of Cr(V)-mediated radical generation and deoxyguanine hydroxylation: ESR and HPLC evidence.
Topics: Animals; Cattle; Chromates; Chromatography, High Pressure Liquid; Deferoxamine; Deoxyguanosine; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Hydroxylation; Oxidation-Reduction | 1992 |
Effects of inorganic iron and myoglobin on in vitro proximal tubular lipid peroxidation and cytotoxicity.
Topics: Acute Kidney Injury; Animals; Benzoates; Benzoic Acid; Deferoxamine; Hydroxides; Hydroxyl Radical; In Vitro Techniques; Iron; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Myoglobin; Perfusion; Rats; Rats, Inbred Strains; Salicylates; Superoxide Dismutase; Thiourea | 1992 |
Iron-induced ascorbate oxidation in plasma as monitored by ascorbate free radical formation. No spin-trapping evidence for the hydroxyl radical in iron-overloaded plasma.
Topics: Ascorbic Acid; Buffers; Catalase; Deferoxamine; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Hydroxides; Hydroxyl Radical; Iron; Iron Chelating Agents; Oxidation-Reduction; Oxygen; Pentetic Acid; Superoxide Dismutase | 1992 |
Quantification of hydroxyl radical and its lack of relevance to myocardial injury during early reperfusion after graded ischemia in rat hearts.
Topics: Animals; Coronary Disease; Deferoxamine; Free Radicals; Gentisates; Heart; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Male; Myocardial Reperfusion Injury; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Time Factors | 1992 |
Activated neutrophils inhibit Na(+)-K(+)-ATPase in canine renal basolateral membrane.
Topics: Animals; Azides; Cell Membrane; Cyclic N-Oxides; Deferoxamine; Dogs; Free Radical Scavengers; Free Radicals; Humans; Hydroxides; Hydroxyl Radical; Kidney Cortex; Kinetics; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Ouabain; Phenanthrolines; Sodium-Potassium-Exchanging ATPase; Superoxides; Tetradecanoylphorbol Acetate | 1992 |
Antiradical effects in L-propionyl carnitine protection of the heart against ischemia-reperfusion injury: the possible role of iron chelation.
Topics: Animals; Carnitine; Deferoxamine; Electron Spin Resonance Spectroscopy; Energy Metabolism; Free Radical Scavengers; Free Radicals; Hydroxides; Hydroxyl Radical; Iron Chelating Agents; Luminescent Measurements; Luminol; Male; Myocardial Reperfusion Injury; Oxidation-Reduction; Rats; Rats, Inbred Strains; Stereoisomerism; Superoxides; Ventricular Function, Left | 1992 |
Protection from cold injury by deferoxamine, an iron chelator.
Topics: Animals; Cold Temperature; Deferoxamine; Fatty Acids, Nonesterified; Free Radicals; Hydroxides; Hydroxyl Radical; Iron; L-Lactate Dehydrogenase; Lipid Peroxidation; Membrane Lipids; Muscles; Phospholipids; Rabbits | 1992 |
Combined mannitol and deferoxamine therapy for myohemoglobinuric renal injury and oxidant tubular stress. Mechanistic and therapeutic implications.
Topics: Acute Kidney Injury; Animals; Deferoxamine; Drug Therapy, Combination; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Iron; Kidney Tubules; Male; Mannitol; Myoglobinuria; Rats; Rats, Inbred Strains | 1992 |
Generation of hydroxyl radical by crocidolite asbestos is proportional to surface [Fe3+].
Topics: Asbestos; Asbestos, Crocidolite; Deferoxamine; Dose-Response Relationship, Drug; Free Radicals; Hydroxides; Hydroxyl Radical; Iron; Kinetics; Thiobarbituric Acid Reactive Substances | 1992 |
Stimulation of lipid peroxidation and hydroxyl-radical generation by the contents of human atherosclerotic lesions.
Topics: Animals; Arteriosclerosis; Cations; Copper; Deferoxamine; Humans; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Iron; Lipid Peroxidation; Microsomes, Liver; Rats; Spectrophotometry, Atomic | 1992 |
Antioxidant and free radical scavenging activities of the iron chelators pyoverdin and hydroxypyrid-4-ones in iron-loaded hepatocyte cultures: comparison of their mechanism of protection with that of desferrioxamine.
Topics: Animals; Antioxidants; Calcium-Binding Proteins; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclic N-Oxides; Deferiprone; Deferoxamine; Ethanol; Free Radical Scavengers; Free Radicals; Hydroxides; Hydroxyl Radical; Iron; Iron Chelating Agents; Kinetics; Lipid Peroxidation; Liver; Malondialdehyde; Oligopeptides; Photolysis; Pigments, Biological; Pyridones; Rats; Rats, Sprague-Dawley | 1992 |
Desferal-Mn(III) in the therapy of diquat-induced cataract in rabbit.
Topics: Animals; Ascorbic Acid; Cataract; Deferoxamine; Diquat; Free Radicals; Glutathione; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Kinetics; Lens, Crystalline; Lipid Peroxidation; Malondialdehyde; Membrane Lipids; Organ Culture Techniques; Organometallic Compounds; Rabbits | 1991 |
Hydrogen peroxide-mediated toxicity for Leishmania donovani chagasi promastigotes. Role of hydroxyl radical and protection by heat shock.
Topics: Animals; Cyclic N-Oxides; Deferoxamine; Dimethyl Sulfoxide; Heat-Shock Proteins; Hot Temperature; Humans; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Leishmania donovani; Macrophages; Mice; Phagocytosis; Transcription, Genetic | 1991 |
Hydrogen peroxide cytotoxicity in LLC-PK1 cells: a role for iron.
Topics: Animals; Cell Death; Cell Line; Deferoxamine; Free Radical Scavengers; Free Radicals; Glucose; Glucose Oxidase; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Iron; Kidney Tubules, Proximal; Thiourea | 1991 |
Hydroxyl radical formation by sickle erythrocyte membranes: role of pathologic iron deposits and cytoplasmic reducing agents.
Topics: Anemia, Sickle Cell; Ascorbic Acid; Deferoxamine; Erythrocyte Membrane; Free Radicals; Glutathione; Heme; Humans; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Iron; Kinetics; Lipid Peroxidation; NAD; NADP; Oxidation-Reduction; Reference Values | 1991 |
Hydrogen peroxide: an endogenous smooth muscle cell hyperpolarizing factor.
Topics: Animals; Coronary Vessels; Deferoxamine; Dinoprost; Endothelium, Vascular; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; In Vitro Techniques; Mannitol; Membrane Potentials; Muscle Contraction; Muscle, Smooth, Vascular; Substance P; Swine | 1991 |
Role for iron in reactive oxygen species-mediated cytotoxicity to cultured rat gastric mucosal cells.
Topics: Animals; Apoproteins; Cell Survival; Cells, Cultured; Deferoxamine; Female; Free Radical Scavengers; Free Radicals; Gastric Mucosa; Glutathione; Hydroxides; Hydroxyl Radical; Iron; Kinetics; Male; Maleates; Rats; Rats, Inbred Strains; Superoxides; Transferrin | 1991 |
Oxygen free radical injury of IEC-18 small intestinal epithelial cell monolayers.
Topics: Animals; Catalase; Cell Line; Deferoxamine; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; In Vitro Techniques; Intestine, Small; Microscopy, Phase-Contrast; Rats; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 1991 |
Nitroxide stable radicals protect beating cardiomyocytes against oxidative damage.
Topics: Animals; Cells, Cultured; Deferoxamine; Heart; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; L-Lactate Dehydrogenase; Myocardium; Nitrogen Oxides; Oxidation-Reduction; Rats | 1991 |
Methylene blue plus light mediates 8-hydroxy 2'-deoxyguanosine formation in DNA preferentially over strand breakage.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Catalase; Deferoxamine; Deoxyguanosine; DNA Damage; DNA, Superhelical; Free Radicals; Hydroxides; Hydroxyl Radical; Light; Magnesium; Mannitol; Methylene Blue; Plasmids; Thiopental; Thiourea | 1990 |
Prooxidant action of desferrioxamine: enhancement of alkaline phosphatase inactivation by interaction with ascorbate system.
Topics: Alkaline Phosphatase; Ascorbic Acid; Deferoxamine; Free Radicals; Hydroxides; Hydroxyl Radical; Kinetics; Nitroblue Tetrazolium; Oxidation-Reduction; Superoxide Dismutase | 1990 |
Induction of the heme oxygenase gene in human skin fibroblasts by hydrogen peroxide and UVA (365 nm) radiation: evidence for the involvement of the hydroxyl radical.
Topics: Cell Survival; Deferoxamine; Fibroblasts; Gene Expression Regulation, Enzymologic; Heme Oxygenase (Decyclizing); Humans; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Mixed Function Oxygenases; Phenanthrolines; RNA, Messenger; Skin; Ultraviolet Rays | 1990 |
Mechanism of protection of alveolar type II cells against paraquat-induced cytotoxicity by deferoxamine.
Topics: Animals; Cell Survival; Cells, Cultured; Chelating Agents; Deferoxamine; Dose-Response Relationship, Drug; Free Radicals; Hydrazones; Hydroxides; Hydroxyl Radical; Male; Paraquat; Pulmonary Alveoli; Putrescine; Pyridoxal; Rats; Rats, Inbred Strains | 1990 |
Hemorrhagic shock-induced bacterial translocation: the role of neutrophils and hydroxyl radicals.
Topics: Animals; Bacterial Physiological Phenomena; Cell Movement; Deferoxamine; Dimethyl Sulfoxide; Free Radicals; Hydroxides; Hydroxyl Radical; Immune Sera; Intestinal Mucosa; Lymph Nodes; Male; Neutrophils; Permeability; Rats; Rats, Inbred Strains; Shock, Hemorrhagic | 1990 |
Evidence against transition metal-independent hydroxyl radical generation by xanthine oxidase.
Topics: Catalase; Deferoxamine; Electron Spin Resonance Spectroscopy; Free Radicals; Hydroxides; Hydroxyl Radical; Kinetics; Metals; Spin Labels; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 1990 |
The effects of an iron chelator on cellular injury induced by vascular stasis caused by hypothermia.
Topics: Animals; Creatine Kinase; Deferoxamine; Hindlimb; Hydroxides; Hydroxyl Radical; Hypothermia, Induced; Iron; L-Lactate Dehydrogenase; Lipid Peroxides; Malondialdehyde; Muscles; Necrosis; Rabbits; Regional Blood Flow; Reperfusion Injury; Temperature | 1990 |
Radioprotection by ascorbic acid, desferal, and mercaptoethylamine.
Topics: Animals; Ascorbic Acid; Deferoxamine; Dose-Response Relationship, Radiation; Female; Free Radicals; Gamma Rays; Hydroxides; Hydroxyl Radical; Male; Mercaptoethylamines; Mice; Mice, Inbred Strains; Peroxides; Radiation-Protective Agents; X-Rays | 1990 |
Microsomal lipid peroxidation and oxy-radicals formation are induced by insoluble iron-containing minerals.
Topics: Animals; Carbon Dioxide; Carbonates; Catalase; Cyclic N-Oxides; Deferoxamine; Ferric Compounds; Ferrosoferric Oxide; Free Radical Scavengers; Hydroxides; Hydroxyl Radical; Iron; Lipid Peroxidation; Male; Malondialdehyde; Microsomes, Liver; Minerals; Oxides; Oxygen; Rats; Rats, Inbred Strains; Silicic Acid; Spin Labels; Sulfides; Superoxide Dismutase | 1990 |
An ESR study of the nitroxide radical of pentastarch-conjugated deferoxamine.
Topics: Deferoxamine; Deoxyribose; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Hydrogen Peroxide; Hydrolysis; Hydroxides; Hydroxyl Radical; Nitrogen Oxides | 1990 |
Iron promoters of the Fenton reaction and lipid peroxidation can be released from haemoglobin by peroxides.
Topics: Apoproteins; Bleomycin; Catalase; Ceruloplasmin; Deferoxamine; Deoxyribose; Hemoglobins; Humans; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Iron; Lipid Peroxides; Peroxides; Transferrin | 1986 |
Modulation of the development of bleomycin-induced fibrosis by deferoxamine.
Topics: Animals; Bleomycin; Collagen; Cricetinae; Deferoxamine; Hydroxides; Hydroxyl Radical; Lipid Peroxides; Lung; Lymphocyte Activation; Mesocricetus; Proteins; Pulmonary Fibrosis | 1988 |
Reactive oxygen species induce antigenic changes in DNA.
Topics: Animals; Antibodies; Ascorbic Acid; Cattle; Deferoxamine; DNA; Epitopes; Free Radicals; Humans; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Immune Sera; Immunoglobulin A; Immunoglobulin G; Immunoglobulin Isotypes; Immunoglobulin M; Lupus Erythematosus, Systemic; Nucleic Acid Denaturation; Oxygen; Thiourea | 1989 |
Inability of desferrioxamine to limit tissue injury in the ischaemic and reperfused rabbit heart.
Topics: Animals; Coronary Disease; Deferoxamine; Free Radicals; Hemodynamics; Hydroxides; Hydroxyl Radical; In Vitro Techniques; Iron Chelating Agents; Lipid Peroxidation; Male; Myocardial Reperfusion Injury; Rabbits | 1989 |
Regular fragmentation of hydrogen peroxide-treated fibronectin.
Topics: Binding Sites; Deferoxamine; Electrophoresis, Polyacrylamide Gel; Fibronectins; Free Radicals; Humans; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Immunoblotting; Macromolecular Substances; Molecular Weight; Pentetic Acid; Peptide Fragments; Polystyrenes; Polyvinyls; Thiourea | 1989 |
Role of hydroxyl radicals in Escherichia coli killing induced by hydrogen peroxide.
Topics: Deferoxamine; Dimethyl Sulfoxide; Escherichia coli; Ethanol; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Iron; Kinetics; Thiourea | 1989 |
Intermediates in the aerobic autoxidation of 6-hydroxydopamine: relative importance under different reaction conditions.
Topics: Aerobiosis; Catalase; Chemical Phenomena; Chemistry; Deferoxamine; Edetic Acid; Formates; Free Radicals; Glucose; Hydrogen Peroxide; Hydroxides; Hydroxydopamines; Hydroxyl Radical; Mannitol; Metals; Oxidation-Reduction; Oxidopamine; Pentetic Acid; Superoxide Dismutase; Superoxides | 1989 |
Damage to the bases in DNA induced by stimulated human neutrophils.
Topics: Catalase; Chemical Phenomena; Chemistry; Deferoxamine; Dimethyl Sulfoxide; DNA; DNA Damage; Free Radicals; Gas Chromatography-Mass Spectrometry; Humans; Hydroxides; Hydroxyl Radical; Iron; Molecular Structure; Neutrophils; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1989 |
Xanthine oxidase-induced injury to endothelium: role of intracellular iron and hydroxyl radical.
Topics: Animals; Deferoxamine; Endothelium, Vascular; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Hypoxanthine; Hypoxanthines; Intracellular Membranes; Iron; Malondialdehyde; Xanthine Oxidase | 1989 |
Differential formation of hydroxyl radicals by adriamycin in sensitive and resistant MCF-7 human breast tumor cells: implications for the mechanism of action.
Topics: Breast Neoplasms; Catalase; Cell Line; Colony-Forming Units Assay; Cyclic N-Oxides; Deferoxamine; Doxorubicin; Drug Resistance; Electron Spin Resonance Spectroscopy; Female; Free Radicals; Glutathione Peroxidase; Humans; Hydroxides; Hydroxyl Radical; Oxygen; Superoxide Dismutase; Tumor Stem Cell Assay | 1987 |
Modulation of normobaric pulmonary oxygen toxicity by hydroxyl radical inhibition.
Topics: Animals; Capillary Permeability; Deferoxamine; Hydroxides; Hydroxyl Radical; Lung; Lung Diseases; Male; Organ Size; Oxygen; Rats; Rats, Inbred Strains; Thiourea | 1987 |
Prevention of hydroxyl radical formation: a critical concept for improving cardioplegia. Protective effects of deferoxamine.
Topics: Animals; Blood Pressure; Cardioplegic Solutions; Coronary Circulation; Deferoxamine; Heart; Heart Arrest, Induced; Hydroxides; Hydroxyl Radical; In Vitro Techniques; Male; Myocardium; Peroxidase; Rats; Rats, Inbred Strains | 1987 |
Oxygen radical injury in the presence of desferal, a specific iron-chelating agent.
Topics: Animals; Deferoxamine; Hydroxides; Hydroxyl Radical; Male; Oxygen; Rats; Rats, Inbred Strains; Superoxide Dismutase; Superoxides | 1987 |
Lipid peroxidation and tissue injury by ferric citrate in paraquat-intoxicated mice.
Topics: Animals; Aspartate Aminotransferases; Deferoxamine; Ethane; Ferric Compounds; Hydroxides; Hydroxyl Radical; Iron; Kidney; Kinetics; Lipid Peroxides; Liver; Male; Mice; NADP; Oxygen; Paraquat; Superoxides; Tissue Distribution; Trichloroacetic Acid | 1988 |
Evidence suggesting a role for hydroxyl radical in passive Heymann nephritis in rats.
Topics: Animals; Antibodies, Anti-Idiotypic; Benzoates; Benzoic Acid; Deferoxamine; Free Radicals; Hydroxides; Hydroxyl Radical; Kidney; Male; Nephritis; Proteinuria; Rats; Rats, Inbred Strains; Superoxide Dismutase; Thiourea | 1988 |
Hydroxy radical as autotoxin in chemotactically activated neutrophils.
Topics: Animals; Catalase; Chemotaxis, Leukocyte; Complement C5; Complement C5a; Deferoxamine; Dimethyl Sulfoxide; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Iron; Lipid Peroxides; Mannitol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Oxidation-Reduction; Rats; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1987 |
Spin trapping of free radical species produced during the microsomal metabolism of ethanol.
Topics: Animals; Chelating Agents; Cytochrome P-450 Enzyme System; Deferoxamine; Electron Spin Resonance Spectroscopy; Ethanol; Ferrous Compounds; Free Radicals; Glutathione; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Iron; Male; Microsomes, Liver; NADP; Nitrogen Oxides; Pyridines; Rats; Rats, Inbred Strains; Resins, Synthetic; Spin Labels | 1988 |
Comparison of the ability of ferric complexes to catalyze microsomal chemiluminescence, lipid peroxidation, and hydroxyl radical generation.
Topics: Adenosine Diphosphate; Animals; Deferoxamine; Edetic Acid; Ferric Compounds; Hydroxides; Hydroxyl Radical; Lipid Peroxides; Luminescent Measurements; Male; Mannitol; Microsomes, Liver; NADP; NADPH-Ferrihemoprotein Reductase; Pentetic Acid; Rats; Rats, Inbred Strains | 1988 |
Cardioplegic arrest superimposed on evolving myocardial ischemia. Improved recovery after inhibition of hydroxyl radical generation by peroxidase or deferoxamine. A 31P nuclear resonance study.
Topics: Animals; Coronary Disease; Deferoxamine; Heart Arrest, Induced; Hydrogen-Ion Concentration; Hydroxides; Hydroxyl Radical; Magnetic Resonance Spectroscopy; Male; Myocardial Reperfusion; Peroxidase; Phosphates; Phosphorus; Rats; Rats, Inbred Strains | 1988 |
Evidence suggesting a role for hydroxyl radical in puromycin aminonucleoside-induced proteinuria.
Topics: Animals; Benzoates; Benzoic Acid; Deferoxamine; Dimethyl Sulfoxide; Hydroxides; Hydroxyl Radical; Male; Proteinuria; Puromycin; Puromycin Aminonucleoside; Rats; Rats, Inbred Strains; Thiourea | 1988 |
Metal chelation therapy, oxygen radicals, and human disease.
Topics: Chelating Agents; Deferoxamine; Free Radicals; Humans; Hydroxides; Hydroxyl Radical; Oxygen | 1985 |
Lipid peroxidation and acute lung injury after thermal trauma to skin. Evidence of a role for hydroxyl radical.
Topics: Animals; Burns; Capillary Permeability; Chelating Agents; Deferoxamine; Dimethyl Sulfoxide; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Lipid Metabolism; Lipid Peroxides; Lung; Lung Diseases; Neutrophils; Rats; Rats, Inbred Strains; Skin; Vitamin E | 1985 |
Evaluation of microsomal pathways of oxidation of alcohols and hydroxyl radical scavenging agents with carbon monoxide and cobalt protoporphyrin IX.
Topics: Alcohols; Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Deferoxamine; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; In Vitro Techniques; Male; Metyrapone; Microsomes, Liver; Oxidation-Reduction; Porphyrins; Proadifen; Protoporphyrins; Rats; Rats, Inbred Strains; Superoxides | 1985 |
Microsomal interactions between iron, paraquat, and menadione: effect on hydroxyl radical production and alcohol oxidation.
Topics: Aminopyrine; Animals; Butanols; Butyrates; Carbon Monoxide; Catalase; Deferoxamine; Drug Interactions; Ethanol; Ethylenes; Flavin-Adenine Dinucleotide; Hydroxides; Hydroxyl Radical; Iron; Microsomes, Liver; Paraquat; Rats; Sulfhydryl Compounds; Superoxide Dismutase; Vitamin K | 1985 |
Free radical damage to deoxyribose by anthracycline, aureolic acid and aminoquinone antitumour antibiotics. An essential requirement for iron, semiquinones and hydrogen peroxide.
Topics: Antibiotics, Antineoplastic; Benzoquinones; Catalase; Deferoxamine; Deoxyribose; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Iron; Naphthacenes; Plicamycin; Quinones; Superoxide Dismutase | 1985 |
[In vitro study on the possible inflammatory mechanism of ferrous ions: effect on the production of oxygen free radicals].
Topics: Arthritis, Rheumatoid; Deferoxamine; Ferric Compounds; Ferrous Compounds; Humans; Hydroxides; Hydroxyl Radical; In Vitro Techniques; Iron; Luminescent Measurements; Neutrophils; Oxygen; Zymosan | 1985 |
Failure of desferrioxamine to modify the toxicity of paraquat in rats.
Topics: Animals; Chelating Agents; Deferoxamine; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Iron; Lung; Male; Paraquat; Rats; Rats, Inbred Strains | 1985 |
Iron mediates paraquat toxicity in Escherichia coli.
Topics: Catalase; Deferoxamine; Drug Synergism; Enzyme Induction; Escherichia coli; Histidine; Hydroxides; Hydroxyl Radical; Iron; Mannitol; Mathematics; Nitrilotriacetic Acid; Paraquat; Superoxide Dismutase | 1986 |
Effect of iron chelation on severity of ocular inflammation in an animal model.
Topics: Animals; Anti-Inflammatory Agents; Antigens; Arrestin; Choroiditis; Deferoxamine; Disease Models, Animal; Free Radicals; Hydroxides; Hydroxyl Radical; Rats; Rats, Inbred Lew; Retinitis; Uveitis | 1986 |
Hemoglobin potentiates central nervous system damage.
Topics: Animals; Brain; Cats; Deferoxamine; Free Radicals; Hemoglobins; Humans; Hydroxides; Hydroxyl Radical; Lipid Peroxides; Mice; Neutrophils; Sodium-Potassium-Exchanging ATPase; Spinal Cord | 1987 |
Hydroxyl radical mediation of immune renal injury by desferrioxamine.
Topics: Acute Kidney Injury; Animals; Antibodies; Basement Membrane; Deferoxamine; Dose-Response Relationship, Drug; Glomerulonephritis; Hydroxides; Hydroxyl Radical; Kidney Glomerulus; Male; Neutrophils; Proteinuria; Rabbits; Sheep; Superoxides | 1986 |
Prooxidant action of desferrioxamine: Fenton-like production of hydroxyl radicals by reduced ferrioxamine.
Topics: Deferoxamine; Electron Spin Resonance Spectroscopy; Ferric Compounds; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Iron; Oxidation-Reduction; Paraquat | 1986 |
A role for iron in oxidant-mediated ischemic injury to intestinal microvasculature.
Topics: Animals; Apoproteins; Capillaries; Capillary Permeability; Cats; Deferoxamine; Free Radicals; Hydroxides; Hydroxyl Radical; Intestines; Iron; Ischemia; Transferrin | 1987 |
Microsomal generation of hydroxyl radicals: its role in microsomal ethanol oxidizing system (MEOS) activity and requirement for iron.
Topics: Alcoholism; Animals; Deferoxamine; Edetic Acid; Ethanol; Free Radicals; Hydroxides; Hydroxyl Radical; Iron; Kinetics; Microsomes, Liver; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Rats | 1987 |
Hydrogen peroxide-induced glutathione depletion and aldehyde dehydrogenase inhibition in erythrocytes.
Topics: Aldehyde Dehydrogenase; Animals; Catalase; Deferoxamine; Erythrocytes; Female; Glutathione; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Lipid Peroxides; Male; Malondialdehyde; Oxidation-Reduction; Rabbits | 1987 |
Reactive oxygen species selectively deplete normal T lymphocytes via a hydroxyl radical dependent mechanism.
Topics: Adult; Antioxidants; Cell Survival; Deferoxamine; Dose-Response Relationship, Radiation; Humans; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Synovitis; T-Lymphocytes | 1987 |
The effect of human serum transferrin and milk lactoferrin on hydroxyl radical formation from superoxide and hydrogen peroxide.
Topics: Apoproteins; Deferoxamine; Electron Spin Resonance Spectroscopy; Female; Free Radicals; Humans; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Kinetics; Lactoferrin; Lactoglobulins; Milk, Human; Pentetic Acid; Pregnancy; Serum Albumin, Bovine; Superoxides; Transferrin | 1984 |
Xanthine oxidase induced depolymerization of hyaluronic acid in the presence of ferritin.
Topics: Animals; Cattle; Chemical Phenomena; Chemistry; Deferoxamine; Edetic Acid; Ferritins; Hyaluronic Acid; Hydroxides; Hydroxyl Radical; Superoxides; Viscosity; Xanthine Oxidase | 1984 |
Stereochemical studies on the cytochrome P-450 and hydroxyl radical dependent pathways of 2-butanol oxidation by microsomes from chow-fed, phenobarbital-treated, and ethanol-treated rats.
Topics: Animals; Butanols; Cytochrome P-450 Enzyme System; Deferoxamine; Ethanol; Free Radicals; Hydroxides; Hydroxyl Radical; Kinetics; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Phenobarbital; Rats; Rats, Inbred Strains; Stereoisomerism | 1984 |
Inhibition of microsomal oxidation of alcohols and of hydroxyl-radical-scavenging agents by the iron-chelating agent desferrioxamine.
Topics: Alcohols; Aminopyrine; Animals; Benzoates; Benzoic Acid; Deferoxamine; Dimethyl Sulfoxide; Edetic Acid; Ferric Compounds; Hydroxides; Hydroxyl Radical; In Vitro Techniques; Male; Methionine; Microsomes, Liver; Oxidation-Reduction; Rats; Rats, Inbred Strains | 1983 |
Organic hydroperoxide-dependent oxidation of ethanol by microsomes: lack of a role for free hydroxyl radicals.
Topics: 1-Butanol; Animals; Butanols; Catalysis; Chemical Phenomena; Chemistry; Deferoxamine; Edetic Acid; Ethanol; Free Radicals; Hydroxides; Hydroxyl Radical; In Vitro Techniques; Male; Microsomes, Liver; Oxidation-Reduction; Peroxides; Rats; Rats, Inbred Strains | 1983 |
Asbestos catalyzes hydroxyl and superoxide radical generation from hydrogen peroxide.
Topics: Asbestos; Asbestos, Amosite; Asbestos, Crocidolite; Asbestos, Serpentine; Catalysis; Deferoxamine; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Superoxides | 1984 |
Mitomycin C-induced deoxyribose degradation inhibited by superoxide dismutase. A reaction involving iron, hydroxyl and semiquinone radicals.
Topics: Animals; Benzoquinones; Cattle; Deferoxamine; Deoxyribose; Edetic Acid; Humans; Hydroxides; Hydroxyl Radical; Iron; Mitomycin; Mitomycins; Pentetic Acid; Quinones; Superoxide Dismutase; Xanthine Oxidase | 1984 |
Conjugated deferoxamine reduces blood-brain barrier disruption in experimental optic neuritis.
Topics: Animals; Blood-Brain Barrier; Capillary Permeability; Deferoxamine; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Gadolinium DTPA; Guinea Pigs; Hydrogen Peroxide; Hydroxyethyl Starch Derivatives; Hydroxyl Radical; Immunohistochemistry; Injections, Intraperitoneal; Magnetic Resonance Imaging; Myelin Sheath; Optic Disk; Optic Nerve; Optic Neuritis; Organometallic Compounds; Pentetic Acid | 1994 |
Novel 21-aminosteroidlike compounds prevent iron-induced free radical-mediated injury to vascular endothelial cells.
Topics: Allopurinol; Animals; Antimetabolites; Antioxidants; Aorta; Butylated Hydroxytoluene; Cattle; Cell Count; Cell Membrane; Cell Survival; Chromans; Deferoxamine; Dogs; Endothelium, Vascular; Free Radical Scavengers; Free Radicals; Hydroxyl Radical; Iron; Iron Chelating Agents; Lipid Peroxidation; Piperazines; Pregnatrienes; Probucol; Pulmonary Artery; Siderophores | 1995 |
Role of hydroxyl radical in the stimulation of arachidonic acid release caused by H2O2 in pulmonary smooth muscle cells: protective effect of anion channel blocker.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Arachidonic Acid; Cells, Cultured; Deferoxamine; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Ion Channels; Muscle, Smooth, Vascular; Pulmonary Artery; Rabbits; Siderophores; Thiourea | 1995 |
Oxygen radical-induced single-strand DNA breaks and repair of the damage in a cell-free system.
Topics: Animals; Carbon-Oxygen Lyases; Cell-Free System; Deferoxamine; DNA; DNA Damage; DNA Polymerase I; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; Endodeoxyribonucleases; Exodeoxyribonucleases; Ferric Compounds; Hydrogen Peroxide; Hydroxyl Radical; Mice; Multienzyme Complexes; Nitrilotriacetic Acid; Plasmids; Sarcoma, Experimental | 1995 |
Ischemia- and reperfusion-sensitive cardiac sympathetic afferents: influence of H2O2 and hydroxyl radicals.
Topics: Animals; Bradykinin; Cats; Deferoxamine; Female; Free Radical Scavengers; Heart Conduction System; Hydrogen Peroxide; Hydroxyl Radical; Iron; Male; Myocardial Ischemia; Myocardial Reperfusion; Neurons, Afferent; Sympathetic Nervous System; Thiourea | 1995 |
Singlet oxygen-trapping reaction as a method of (1)O2 detection: role of some reducing agents.
Topics: Ascorbic Acid; Cations; Cyclic N-Oxides; Deferoxamine; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Iron; Oxidation-Reduction; Oxygen; Piperidones; Reactive Oxygen Species; Triacetoneamine-N-Oxyl; Ultraviolet Rays; Xanthine Oxidase | 1995 |
Influence of hepatic artery occlusion and desferrioxamine on liver-tumour growth.
Topics: Adenocarcinoma; Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Cell Division; Deferoxamine; Female; Hepatic Artery; Hydroxyl Radical; Iron; Iron Chelating Agents; Ischemia; Ligation; Liver; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred WF | 1995 |
High susceptibility to paraquat-driven lipid peroxidation of cultured hepatocytes loaded with linolenic acid.
Topics: alpha-Linolenic Acid; Animals; Antioxidants; Ascorbic Acid; Cells, Cultured; Deferoxamine; Fatty Acids, Unsaturated; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Lipid Peroxidation; Liver; Male; Paraquat; Rats; Rats, Wistar | 1995 |
DNA base modifications and membrane damage in cultured mammalian cells treated with iron ions.
Topics: Animals; Ascorbic Acid; Cell Membrane; Cell Membrane Permeability; Cells, Cultured; Deferoxamine; Dimethyl Sulfoxide; DNA Damage; Ferrous Compounds; Free Radical Scavengers; Gas Chromatography-Mass Spectrometry; Hydroxyl Radical; Mice; Purines; Pyrimidines; Spectrometry, Fluorescence | 1995 |
Desferrioxamine inhibition of the hydroxyl radical-like reactivity of peroxynitrite: role of the hydroxamic groups.
Topics: Cyclic N-Oxides; Deferoxamine; Dimethyl Sulfoxide; Electron Spin Resonance Spectroscopy; Hydrogen Peroxide; Hydroxamic Acids; Hydroxyl Radical; Luminescent Measurements; Luminol; Nitrates; Oxidation-Reduction; Spectrophotometry | 1995 |
Direct effects of reactive oxygen species on cochlear outer hair cell shape in vitro.
Topics: Animals; Catalase; Cell Size; Cochlea; Colorimetry; Deferoxamine; Female; Free Radical Scavengers; Guinea Pigs; Hair Cells, Auditory, Outer; Hydrogen Peroxide; Hydroxyl Radical; Male; Perilymph; Superoxide Dismutase; Superoxides; Video Recording | 1995 |
Iron supplementation generates hydroxyl radical in vivo. An ESR spin-trapping investigation.
Topics: 2,2'-Dipyridyl; 5'-Nucleotidase; Alanine Transaminase; Alkaline Phosphatase; Animal Feed; Animals; Bile Acids and Salts; Cyclic N-Oxides; Deferoxamine; Dimethyl Sulfoxide; Electron Spin Resonance Spectroscopy; Ferric Compounds; Food, Fortified; Hydroxyl Radical; Iron; L-Iditol 2-Dehydrogenase; L-Lactate Dehydrogenase; Liver; Male; Nitrogen Oxides; Rats; Rats, Sprague-Dawley; Reference Values; Spin Labels | 1995 |
Cold-induced brain edema in mice. Involvement of extracellular superoxide dismutase and nitric oxide.
Topics: Amino Acid Oxidoreductases; Animals; Brain; Brain Edema; Cold Temperature; Deferoxamine; Free Radical Scavengers; Hydroxides; Hydroxyl Radical; Iron Chelating Agents; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Nitric Oxide; Nitric Oxide Synthase; Superoxide Dismutase | 1993 |
Complement activation by the hydroxyl radical during intestinal reperfusion.
Topics: Animals; Chemotactic Factors; Complement Activation; Complement C5a; Deferoxamine; Disease Models, Animal; Hydroxyl Radical; Intestines; Male; Neutrophils; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Thiourea | 1994 |
Peroxidation of model lipoprotein solutions sensitized by photoreduction of ferritin by 365 nm radiation.
Topics: Animals; Deferoxamine; Dose-Response Relationship, Radiation; Ferritins; Horses; Humans; Hydrogen Peroxide; Hydroxyl Radical; Iron; Kinetics; Lipid Peroxidation; Lipoproteins, HDL; Oxidation-Reduction; Quantum Theory; Spleen; Thiobarbituric Acid Reactive Substances; Tryptophan; Ultraviolet Rays | 1994 |
Characterization of exogenous hydroxyl radical effects on myocardial function, metabolism and ultrastructure.
Topics: Adenosine Triphosphate; Animals; Catalase; Deferoxamine; Dose-Response Relationship, Drug; Edetic Acid; Heart; Hydrogen Peroxide; Hydroxyl Radical; In Vitro Techniques; Lipid Peroxidation; Male; Microscopy, Electron; Myocardium; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 1994 |
Protection of the transiently ischemic cat retina by zinc-desferrioxamine.
Topics: Animals; Cats; Deferoxamine; Electroretinography; Fundus Oculi; Hydroxybenzoates; Hydroxyl Radical; Injections, Intravenous; Ischemia; Organometallic Compounds; Reperfusion Injury; Retinal Vessels; Salicylates; Salicylic Acid | 1994 |
Comparative sugar degradation by (OH). produced by the iron-driven Fenton reaction and gamma radiolysis.
Topics: Benzoates; Benzoic Acid; Cobalt Radioisotopes; Deferoxamine; Deoxyribose; Formates; Gamma Rays; Hydroxyl Radical; Iron; Iron Chelating Agents; Mannitol; Oxidation-Reduction; Pentetic Acid; Pentoxifylline; Thiobarbituric Acid Reactive Substances | 1994 |
Neutrophil-mediated endothelial angiotensin-converting enzyme dysfunction: role of oxygen-derived free radicals.
Topics: Animals; Cells, Cultured; Deferoxamine; Endothelium, Vascular; Hydroxyl Radical; Mercaptoethanol; Neutrophils; Peptidyl-Dipeptidase A; Phorbol Esters; Reactive Oxygen Species; Sodium Cyanide; Tetradecanoylphorbol Acetate | 1993 |
Failure of deferoxamine to reduce myocardial infarct size in a primate model of ischemia-reperfusion injury.
Topics: Animals; Deferoxamine; Disease Models, Animal; Electrocardiography; Female; Free Radicals; Hydroxyl Radical; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Papio | 1993 |
Antagonizing the hydroxyl ion free radical (HO.) does not abolish reperfusion ventricular fibrillation in anesthetized dogs.
Topics: Anesthesia; Animals; Deferoxamine; Dogs; Female; Free Radical Scavengers; Hemodynamics; Hydroxyl Radical; Male; Myocardial Reperfusion; Thiourea; Ventricular Fibrillation | 1993 |
Vanadium induced hemolysis of vitamin E deficient erythrocytes in Hepes buffer.
Topics: Analysis of Variance; Animals; Chelating Agents; Cricetinae; Deferoxamine; Erythrocytes; Free Radical Scavengers; Free Radicals; Hemolysis; HEPES; Hydroxyl Radical; Male; Mesocricetus; NADP; Phosphates; Tromethamine; Vanadates; Vanadium; Vitamin E Deficiency | 1994 |
The neurotoxicity of iron and nitric oxide. Relevance to the etiology of Parkinson's disease.
Topics: Animals; Deferoxamine; Dominance, Cerebral; Ferritins; Free Radicals; Humans; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Injections, Intraventricular; Iron; Lipid Peroxidation; Nitric Oxide; Oxidopamine; Parkinson Disease; Parkinson Disease, Secondary; Rats; Stereotyped Behavior; Substantia Nigra | 1993 |
Electron spin resonance spin-trapping investigation into the effects of paraquat and desferrioxamine on hydroxyl radical generation during acute iron poisoning.
Topics: Animals; Cyclic N-Oxides; Deferoxamine; Dimethyl Sulfoxide; Electron Spin Resonance Spectroscopy; Free Radicals; Hydroxides; Hydroxyl Radical; Iron; Male; Models, Chemical; Nitrogen Oxides; Paraquat; Rats; Rats, Sprague-Dawley; Spin Labels | 1993 |
Generation of free radicals from hydrogen peroxide and lipid hydroperoxides in the presence of Cr(III).
Topics: Benzene Derivatives; Chromium; Cyclic N-Oxides; Deferoxamine; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxides; Hydroxyl Radical; Lipid Peroxides; Pentetic Acid; Peroxides; Spin Labels; tert-Butylhydroperoxide | 1993 |
H2O2-mediated damage to lysosomal membranes of J-774 cells.
Topics: Acridine Orange; Adenosine Triphosphate; Animals; Cell Death; Chlorides; Cysteine Proteinase Inhibitors; Deferoxamine; Endocytosis; Ferric Compounds; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Intracellular Membranes; Kinetics; Leucine; Lymphoma, Large B-Cell, Diffuse; Lysosomes; Mice; Microscopy, Electron; Trypan Blue; Tumor Cells, Cultured | 1993 |
Activation of ischemia- and reperfusion-sensitive abdominal visceral C fiber afferents. Role of hydrogen peroxide and hydroxyl radicals.
Topics: Abdomen; Action Potentials; Animals; Cats; Deferoxamine; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Ischemia; Nerve Fibers; Neurons, Afferent; Reactive Oxygen Species; Reperfusion; Thiourea; Viscera | 1993 |
Metal chelators reverse the action of hydrogen peroxide in rat luteal cells.
Topics: Animals; Cell Membrane Permeability; Cells, Cultured; Chelating Agents; Corpus Luteum; Cyclic AMP; Deferoxamine; Ethylenediamines; Female; Free Radical Scavengers; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Luteinizing Hormone; Penicillamine; Phenanthrolines; Progesterone; Rats; Rats, Inbred Strains; Receptors, LH; Signal Transduction | 1993 |
Direct evidence that the hydroxyl radical plays a pathogenetic role in myocardial "stunning" in the conscious dog and demonstration that stunning can be markedly attenuated without subsequent adverse effects.
Topics: Animals; Coronary Circulation; Deferoxamine; Dogs; Female; Hemodynamics; Hydroxides; Hydroxyl Radical; Male; Myocardial Contraction; Myocardial Ischemia; Oxygen; Tiopronin; Ventricular Function, Left | 1993 |
Iron, heme oxygenase, and glutathione: effects on myohemoglobinuric proximal tubular injury.
Topics: Animals; Cell-Free System; Deferoxamine; Free Radical Scavengers; Glutathione; Glycerol; Heme Oxygenase (Decyclizing); Hydroxyl Radical; Iron; Iron Chelating Agents; Kidney Tubules; Lipid Peroxides; Male; Myoglobinuria; Rats; Rats, Sprague-Dawley; Reference Values | 1995 |
Generation of reactive oxygen species by Co(II) from H2O2 in the presence of chelators in relation to DNA damage and 2'-deoxyguanosine hydroxylation.
Topics: Anserine; Azides; Chelating Agents; Chromatography, High Pressure Liquid; Cobalt; Deferoxamine; Deoxyguanosine; DNA Damage; Electron Spin Resonance Spectroscopy; Electrophoresis; Ethanol; Formates; Hydrogen Peroxide; Hydroxyl Radical; Hydroxylation; Mutagens; Oxidation-Reduction; Phenanthrolines; Reactive Oxygen Species; Sodium Azide; Spectrophotometry, Ultraviolet | 1996 |
Fluid resuscitation with deferoxamine hetastarch complex attenuates the lung and systemic response to smoke inhalation.
Topics: Animals; Deferoxamine; Female; Hydroxyethyl Starch Derivatives; Hydroxyl Radical; Lipid Peroxidation; Lung; Oxygen Consumption; Resuscitation; Sheep; Smoke Inhalation Injury | 1996 |
Manganese-induced hydroxyl radical formation in rat striatum is not attenuated by dopamine depletion or iron chelation in vivo.
Topics: Animals; Corpus Striatum; Deferoxamine; Dopamine; Dose-Response Relationship, Drug; Hydroxyl Radical; Iron; Iron Chelating Agents; Male; Manganese; Molecular Weight; Neurotoxins; Osmolar Concentration; Oxidopamine; Rats; Rats, Wistar; Reserpine; Time Factors | 1996 |
Benzene metabolites enhance reactive oxygen species generation in HL60 human leukemia cells.
Topics: Aldehydes; Benzene Derivatives; Benzoquinones; Carcinogens; Catalase; Deferoxamine; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Free Radical Scavengers; HL-60 Cells; Humans; Hydrogen Peroxide; Hydroquinones; Hydroxyl Radical; Lipid Peroxidation; Phenols; Reactive Oxygen Species; Sorbic Acid; Structure-Activity Relationship; Superoxide Dismutase | 1996 |
Protective role of anion channel blocker in lipid peroxidation caused by H2O2 in microsomes of bovine pulmonary arterial smooth muscle tissue.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Cattle; Deferoxamine; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Ion Channels; Lipid Peroxidation; Microsomes; Muscle, Smooth, Vascular; Pulmonary Artery; Thiourea | 1996 |
Ascorbate-stimulated lipid peroxidation in human brain is dependent on iron but not on hydroxyl radical.
Topics: Adult; Ascorbic Acid; Brain; Catalase; Caudate Nucleus; Cerebellum; Cerebral Cortex; Chelating Agents; Deferoxamine; Free Radical Scavengers; Humans; Hydroxyl Radical; Iron; Lipid Peroxides; Mannitol; Middle Aged; Oxidation-Reduction; Superoxide Dismutase | 1996 |
Hydroxyl radical production during myocardial ischemia and reperfusion in cats.
Topics: Animals; Cats; Deferoxamine; Female; Free Radical Scavengers; Heart Ventricles; Hydroxyl Radical; Lactic Acid; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Organ Size; Siderophores; Thiourea | 1996 |
Inhibition of human neutrophil binding to hydrogen peroxide-treated endothelial cells by cAMP and hydroxyl radical scavengers.
Topics: 1-Methyl-3-isobutylxanthine; Analysis of Variance; Bucladesine; Cell Adhesion; Cells, Cultured; Cyclic AMP; Deferoxamine; Endothelium, Vascular; Free Radical Scavengers; Glutathione; Humans; Hydrogen Peroxide; Hydroxyl Radical; Hypoxanthine; Isoproterenol; Neutrophils; Pentoxifylline; Tetradecanoylphorbol Acetate; Thrombin; Transferrin; Umbilical Veins; Xanthine Oxidase | 1996 |
Direct effects of intraperilymphatic reactive oxygen species generation on cochlear function.
Topics: Action Potentials; Analysis of Variance; Animals; Antidotes; Auditory Threshold; Catalase; Cochlea; Cochlear Microphonic Potentials; Deferoxamine; Enzyme Inhibitors; Guinea Pigs; Hydrogen Peroxide; Hydroxyl Radical; Perilymph; Potassium Cyanide; Reactive Oxygen Species; Spectrophotometry, Ultraviolet; Superoxide Dismutase; Superoxides; Xanthine; Xanthine Oxidase; Xanthines | 1996 |
Involvement of hydroxyl radical in the immediate ventilatory responses to inhaled wood smoke in rats.
Topics: Animals; Capsaicin; Deferoxamine; Free Radical Scavengers; Hydroxyl Radical; Iron; Rats; Rats, Sprague-Dawley; Respiratory Mechanics; Siderophores; Smoke; Thiourea; Wood | 1997 |
Role of low molecular weight iron in functional preconditioning of the isolated rat heart.
Topics: Animals; Deferoxamine; Heart; Hemodynamics; Hydroxyl Radical; In Vitro Techniques; Iron; Iron Chelating Agents; Ischemic Preconditioning, Myocardial; Male; Models, Cardiovascular; Molecular Weight; Myocardial Contraction; Myocardial Reperfusion; Rats; Rats, Sprague-Dawley; Siderophores | 1997 |
Hydroxyl radical is the major causative factor in stress-induced gastric ulceration.
Topics: Amanitins; Animals; Chelating Agents; Cold Temperature; Copper; Cyclic N-Oxides; Deferoxamine; Gastric Mucosa; Glutathione; Hydrogen Peroxide; Hydroxyl Radical; Lipid Peroxidation; Nitrogen Oxides; Peroxidases; Proteins; Rats; Rats, Wistar; Reactive Oxygen Species; Spin Labels; Stomach Ulcer; Stress, Physiological; Superoxide Dismutase | 1997 |
Synthesis of Cr(IV)-GSH, its identification and its free hydroxyl radical generation: a model compound for Cr(VI) carcinogenicity.
Topics: Carcinogens; Chromates; Chromium; Cyclic N-Oxides; Deferoxamine; Electron Spin Resonance Spectroscopy; Glutathione; Hydrogen Peroxide; Hydroxyl Radical; Oxidation-Reduction; Spin Labels | 1997 |
Interaction of liver methionine adenosyltransferase with hydroxyl radical.
Topics: Amino Acid Substitution; Animals; Binding Sites; CHO Cells; Cricetinae; Cysteine; Deferoxamine; Glutathione; Hydrogen Peroxide; Hydroxyl Radical; Kinetics; Liver; Methionine Adenosyltransferase; Models, Structural; Mutagenesis, Site-Directed; Protein Conformation; Rats; Recombinant Proteins; Transfection | 1997 |
Enhanced luminescence study of liver homogenate response to oxidative stress.
Topics: Animals; Borates; Cytochrome c Group; Deferoxamine; Edetic Acid; Ferrous Compounds; Free Radical Scavengers; Hydroxyl Radical; Liver; Luminescent Measurements; Luminol; Oxidative Stress; Peroxidase; Peroxides; Photometry; Rats; Rats, Wistar; tert-Butylhydroperoxide | 1995 |
Free radical activity of PM10: iron-mediated generation of hydroxyl radicals.
Topics: Air Pollutants; Antidotes; Chromatography, High Pressure Liquid; Deferoxamine; Electron Probe Microanalysis; Hydrogen-Ion Concentration; Hydroxyl Radical; Iron; Microscopy, Electron, Scanning; Particle Size; Plasmids; Spectrometry, X-Ray Emission | 1997 |
Effects of 1,10-phenanthroline and hydrogen peroxide in Escherichia coli: lethal interaction.
Topics: 2,2'-Dipyridyl; Benzoates; Benzoic Acid; Chelating Agents; Copper; Deferoxamine; Escherichia coli; Ethanol; Exodeoxyribonucleases; Ferric Compounds; Ferrous Compounds; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Intercalating Agents; Iron; Oxidants; Phenanthrolines; Thiourea | 1997 |
Apparent role of hydroxyl radicals in oxidative brain injury induced by sodium nitroprusside.
Topics: Animals; Ascorbic Acid; Brain Injuries; Deferoxamine; Hydrogen Peroxide; Hydroxyl Radical; In Vitro Techniques; Iron; Lipid Peroxidation; Male; Nerve Degeneration; Nitric Oxide; Nitroprusside; Oxidative Stress; Oxyhemoglobins; Penicillamine; Rats; Rats, Sprague-Dawley | 1998 |
Complement activation following reoxygenation of hypoxic human endothelial cells: role of intracellular reactive oxygen species, NF-kappaB and new protein synthesis.
Topics: Cell Hypoxia; Cells, Cultured; Complement Activation; Complement C3b; Deferoxamine; Dose-Response Relationship, Drug; Endothelium, Vascular; Free Radical Scavengers; Humans; Hydrogen Peroxide; Hydroxyl Radical; NF-kappa B; Oxypurinol; Protein Biosynthesis; Reactive Oxygen Species; Reperfusion Injury; Thiourea; Umbilical Veins | 1998 |
Involvement of oxygen free radicals in ischaemia-reperfusion injury to murine tumours: role of nitric oxide.
Topics: Adenocarcinoma; Animals; Catalase; Deferoxamine; Endothelium, Vascular; Female; Free Radical Scavengers; Hydroxyl Radical; Hydroxylation; L-Lactate Dehydrogenase; Mammary Neoplasms, Experimental; Mice; Mice, Inbred CBA; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Reperfusion Injury; Salicylates; Salicylic Acid; Sarcoma, Small Cell | 1998 |
Sensitivity of canine intrinsic cardiac neurons to H2O2 and hydroxyl radical.
Topics: Animals; Antioxidants; Atrial Function, Left; Blood Pressure; Cromakalim; Deferoxamine; Dogs; Electrocardiography; Female; Heart; Heart Atria; Heart Rate; Hemodynamics; Hydrogen Peroxide; Hydroxyl Radical; Male; Neurons; Potassium Channels; Ventricular Function, Right | 1998 |
Involvement of a local fenton reaction in the reciprocal modulation by O2 of the glucagon-dependent activation of the phosphoenolpyruvate carboxykinase gene and the insulin-dependent activation of the glucokinase gene in rat hepatocytes.
Topics: Animals; Biochemistry; Cells, Cultured; Deferoxamine; Enzyme Activation; Glucagon; Glucokinase; Hydroxyl Radical; Image Processing, Computer-Assisted; Insulin; Iron; Liver; Male; Microscopy, Confocal; Oxygen; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Rats, Wistar; Rhodamines; Spectrometry, Fluorescence; Thiourea; X-Rays | 1998 |
The effects of methamphetamine on the production of free radicals and oxidative stress.
Topics: Animals; Corpus Striatum; Deferoxamine; Dopamine; Hydroxyl Radical; Iron; Lipid Peroxidation; Male; Methamphetamine; Oxidative Stress; Rats; Rats, Sprague-Dawley; Uric Acid | 1998 |
Studies by electron paramagnetic resonance of the importance of iron in the hydroxyl scavenging properties of ascorbic acid in plasma: effects of iron chelators.
Topics: Animals; Apoproteins; Ascorbic Acid; Deferoxamine; Edetic Acid; Electron Spin Resonance Spectroscopy; Ferrous Compounds; Free Radical Scavengers; Hydroxyl Radical; Iron; Iron Chelating Agents; Male; Rats; Rats, Wistar; Transferrin | 1998 |
Inhibition of skeletal sarcoplasmic reticulum Ca2+-ATPase activity by deferoxamine nitroxide free radical.
Topics: Animals; Calcium-Transporting ATPases; Chelating Agents; Deferoxamine; Dogs; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Horseradish Peroxidase; Hydrogen Peroxide; Hydroxyl Radical; Iron; Masseter Muscle; Microsomes; Nitrogen Oxides; Sarcoplasmic Reticulum | 1999 |
Iron-dependent human platelet activation and hydroxyl radical formation: involvement of protein kinase C.
Topics: Adult; Aspirin; Blood Platelets; Catalase; Chelating Agents; Collagen; Deferoxamine; Deoxyribose; Diuretics, Osmotic; Dose-Response Relationship, Drug; Edetic Acid; Enzyme Inhibitors; Female; Humans; Hydroxyl Radical; Indoles; Iron; Isoquinolines; Male; Maleimides; Mannitol; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Kinase C; Sulfonamides; Thromboxane A2; Thromboxane B2 | 1999 |
Effect of superoxide dismutase, catalase, chelating agents, and free radical scavengers on the toxicity of alloxan to isolated pancreatic islets in vitro.
Topics: 1-Butanol; Alloxan; Animals; Antioxidants; Catalase; Chelating Agents; Deferoxamine; Diabetes Mellitus, Experimental; Dimethyl Sulfoxide; Free Radical Scavengers; Hydroxyl Radical; In Vitro Techniques; Islets of Langerhans; Mice; Mice, Obese; Superoxide Dismutase | 1999 |
The effect of quinine on outer hair cell shape, compliance and force.
Topics: Animals; Azepines; Calmodulin; Compliance; Deferoxamine; Enzyme Inhibitors; Free Radical Scavengers; Guinea Pigs; Hair Cells, Auditory, Outer; Hydroxyl Radical; Motion; Myosin-Light-Chain Kinase; Quinine; Trifluoperazine | 1999 |
Hydroxyl radical generation and lipid peroxidation in C2C12 myotube treated with iodoacetate and cyanide.
Topics: Animals; Cell Line; Cyclic N-Oxides; Deferoxamine; Drug Resistance; Electron Spin Resonance Spectroscopy; Hydroxyl Radical; Iodoacetates; Iron Chelating Agents; Kinetics; L-Lactate Dehydrogenase; Lipid Peroxidation; Malondialdehyde; Mice; Muscle, Skeletal; Sodium Cyanide; Spin Labels; Superoxide Dismutase | 1999 |
Studies of free radical-mediated cryoinjury in the unicellular green alga Euglena gracilis using a non-destructive hydroxyl radical assay: a novel approach for developing protistan cryopreservation strategies.
Topics: Animals; Cell Survival; Chromatography, Gas; Cryopreservation; Cryoprotective Agents; Deferoxamine; Dimethyl Sulfoxide; Euglena gracilis; Free Radicals; Hydroxyl Radical; Iron Chelating Agents; Methane; Oxidative Stress; Photosynthesis; Temperature | 2000 |
Interaction between 6-hydroxydopamine and transferrin: "Let my iron go".
Topics: Animals; Ascorbic Acid; Behavior, Animal; Deferoxamine; Electron Spin Resonance Spectroscopy; Ferric Compounds; Ferrozine; Free Radicals; Humans; Hydroxyl Radical; Injections, Intraperitoneal; Iron; Iron Chelating Agents; Male; Mice; Mice, Inbred A; Oxidopamine; Transferrin | 2000 |
Role of molecular oxygen in the generation of hydroxyl and superoxide anion radicals during enzymatic Cr(VI) reduction and its implication to Cr(VI)-induced carcinogenesis.
Topics: Carcinogenicity Tests; Carcinogens; Chelating Agents; Chromium; Deferoxamine; DNA; DNA Damage; Electron Spin Resonance Spectroscopy; Glutathione Reductase; Hydrogen Peroxide; Hydroxyl Radical; NADP; Oxidation-Reduction; Oxygen; Oxygen Consumption; Superoxides | 2000 |
Detection of dichromate (VI)-induced DNA strand breaks and formation of paramagnetic chromium in multiple mouse organs.
Topics: Animals; Chromium; Deferoxamine; DNA Fragmentation; Electron Spin Resonance Spectroscopy; Electrophoresis; Free Radical Scavengers; Hydroxyl Radical; Iron Chelating Agents; Male; Mice; Potassium Dichromate; Thiourea | 2001 |
Singlet oxygen-dependent hydroxyl radical formation during uroporphyrin-mediated photosensitization in the presence of NADPH.
Topics: Animals; Catalase; Cattle; Deferoxamine; Electron Spin Resonance Spectroscopy; Ganglionic Blockers; Hydrogen Peroxide; Hydroxyl Radical; Light; Models, Chemical; NADP; Oxygen; Piperidones; Time Factors; Triacetoneamine-N-Oxyl; Up-Regulation; Uroporphyrins | 2000 |
Suppression of Ca2+ influx through L-type voltage-dependent calcium channels by hydroxyl radical in mouse cerebral cortical neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium Signaling; Cells, Cultured; Cerebral Cortex; Deferoxamine; Ferrous Compounds; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Ion Channel Gating; Ion Transport; Iron Chelating Agents; Mannitol; Mice; Nerve Tissue Proteins; Neurons; Nifedipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Potassium Chloride; Thiourea | 2001 |
Ca(2+)-activated K+ channel inhibition by reactive oxygen species.
Topics: Animals; Calcium; Cysteine; Deferoxamine; Dithiothreitol; Female; Humans; Hydrogen Peroxide; Hydroxyl Radical; Ion Channel Gating; Iron Chelating Agents; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Large-Conductance Calcium-Activated Potassium Channels; Lipid Bilayers; Muscle, Skeletal; Oocytes; Oxidants; Patch-Clamp Techniques; Potassium Channels, Calcium-Activated; Reactive Oxygen Species; Xenopus laevis | 2002 |
Cleavage of the fifth component of human complement and release of a split product with C5a-like activity by crystalline silica through free radical generation and kallikrein activation.
Topics: Adult; Chemotaxis; Complement Activation; Complement C5; Complement C5a; Deferoxamine; Female; Free Radical Scavengers; Humans; Hydroxyl Radical; Iron; Iron Chelating Agents; Kallikreins; Male; Middle Aged; Neutrophils; Quartz; Thiourea; Zymosan | 2002 |
Evidence that hydroxyl radicals mediate auxin-induced extension growth.
Topics: 2,4-Dichlorophenoxyacetic Acid; Ascorbic Acid; Benzoates; Catecholamines; Cell Wall; Cotyledon; Deferoxamine; Hydrogen Peroxide; Hydroxyl Radical; Imidazolines; Indoleacetic Acids; NAD; NADP; Naphthaleneacetic Acids; Organometallic Compounds; Oxygen; Reactive Oxygen Species; Superoxide Dismutase; Superoxides; Zea mays | 2002 |
Regulation of xanthine oxidoreductase by intracellular iron.
Topics: 3T3 Cells; Animals; Copper; Deferoxamine; Free Radical Scavengers; Humans; Hydroxyl Radical; Intracellular Membranes; Iron; Mice; Oxidoreductases; Transcription, Genetic; Xanthine | 2002 |
Ageing exacerbates the cardiotoxicity of hydrogen peroxide through the Fenton reaction in rats.
Topics: Aging; Animals; Deferoxamine; Hydrogen Peroxide; Hydroxyl Radical; Iron; Iron Chelating Agents; Male; Myocardial Contraction; Myocardium; Myocytes, Cardiac; Oxidants; Rats; Rats, Wistar | 2003 |
Effect of proteins and amino acids on oxidation of liposomes by hydroxyl and peroxyl free radicals.
Topics: Amino Acids; Chloroform; Deferoxamine; Dose-Response Relationship, Drug; Free Radicals; Hydroxyl Radical; Iron Chelating Agents; Lipid Metabolism; Lipid Peroxidation; Liposomes; Muramidase; Oxygen; Phospholipids; Proteins | 2002 |
Intralysosomal iron: a major determinant of oxidant-induced cell death.
Topics: Ammonium Chloride; Animals; Apoptosis; Cells, Cultured; Deferoxamine; Electron Spin Resonance Spectroscopy; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxyl Radical; Iron; Lysosomes; Macrophages; Mice; Oxidants; Oxidation-Reduction; Oxidative Stress; Peptide Hydrolases | 2003 |
Prevention of oxidant-induced cell death by lysosomotropic iron chelators.
Topics: Animals; Antioxidants; Apoptosis; Caspases; Cells, Cultured; Deferoxamine; Electron Spin Resonance Spectroscopy; Enzyme Activation; Free Radicals; Hydrogen Peroxide; Hydroxyl Radical; Iron; Iron Chelating Agents; Lysosomes; Macrophages; Membrane Potentials; Mice; Mitochondria; Oxidation-Reduction; Oxidative Stress; Thioctic Acid | 2003 |
Deferoxamine reduces and nitric oxide synthase inhibition increases neutrophil-mediated myotube injury.
Topics: Catalase; CD18 Antigens; Chromium; Chromium Radioisotopes; Culture Media, Conditioned; Deferoxamine; Humans; Hydroxyl Radical; Iron Chelating Agents; Isothiuronium; Luminescent Measurements; Muscle Fibers, Skeletal; Neutrophils; Nitric Oxide Synthase; Reactive Oxygen Species; Superoxide Dismutase | 2003 |
Oxidative damage of DNA by the reaction of amino acid with methylglyoxal in the presence of Fe(III).
Topics: Catalase; Deferoxamine; DNA Damage; Free Radical Scavengers; Hydroxyl Radical; Iron; Iron Chelating Agents; Lysine; Plasmids; Pyruvaldehyde; Superoxides | 2003 |
[Study on silica induced DNA damage and its influence factor].
Topics: Animals; Calcium; Comet Assay; Cricetinae; Cricetulus; Deferoxamine; DNA Damage; Dose-Response Relationship, Drug; Hydroxyl Radical; Silicon Dioxide; Verapamil | 2002 |
Increased reactive oxygen species in rostral ventrolateral medulla contribute to neural mechanisms of hypertension in stroke-prone spontaneously hypertensive rats.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Animals; Blood Pressure; Brain Chemistry; Catalase; Cyclic N-Oxides; Deferoxamine; Genetic Predisposition to Disease; Genetic Therapy; Glutamic Acid; Hydrogen Peroxide; Hydroxyl Radical; Hypertension; Lipid Peroxidation; Male; Medulla Oblongata; Norepinephrine; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Recombinant Fusion Proteins; Spin Labels; Stroke; Superoxide Dismutase; Superoxides; Sympathetic Nervous System; Thiobarbituric Acid Reactive Substances; Transduction, Genetic; Vasomotor System | 2004 |
In vivo oxygen radical generation in the skin of the protoporphyria model mouse with visible light exposure: an L-band ESR study.
Topics: Animals; Antifungal Agents; Catalase; Deferoxamine; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Griseofulvin; Hydroxyl Radical; Iron Chelating Agents; Light; Male; Mice; Porphyria, Hepatoerythropoietic; Reactive Oxygen Species; Skin; Superoxide Dismutase | 2004 |
Iron chelation abrogates excessive formation of hydroxyl radicals and lipid peroxidation products in monocytes of patients with Eales' disease: direct evidence using electron spin resonance spectroscopy.
Topics: Adult; Deferoxamine; Electron Spin Resonance Spectroscopy; Humans; Hydroxyl Radical; Iron; Iron Chelating Agents; Lipid Peroxidation; Male; Monocytes; Oxidative Stress; Pentetic Acid; Retinal Vasculitis; Spectrophotometry, Atomic; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Thiobarbituric Acid Reactive Substances | 2004 |
Evidence of reactive oxygen species generation in synovial fluid from patients with temporomandibular disease by electron spin resonance spectroscopy.
Topics: Adolescent; Adult; Deferoxamine; Electron Spin Resonance Spectroscopy; Female; Humans; Hydroxyl Radical; Male; Middle Aged; Reactive Oxygen Species; Spin Labels; Superoxide Dismutase; Synovial Fluid; Temporomandibular Joint Disorders | 2004 |
Ischaemic preconditioning but not isoflurane prevents post-ischaemic production of hydroxyl radicals in a canine model of ischaemia-reperfusion.
Topics: Anesthetics, Inhalation; Animals; Antidotes; Blood Pressure; Catechols; Deferoxamine; Dogs; Heart Rate; Hydrogen-Ion Concentration; Hydroxybenzoates; Hydroxyl Radical; Ischemic Preconditioning, Myocardial; Isoflurane; Lactic Acid; Myocardial Reperfusion Injury; Myocardium; Oxygen Consumption; Salicylates | 2005 |
Moderation of morphogenetic and oxidative stress responses in flax in vitro cultures by hydroxynonenal and desferrioxamine.
Topics: Aldehydes; Cells, Cultured; Deferoxamine; Dose-Response Relationship, Drug; Flax; Hydroxyl Radical; Hypocotyl; Oxidative Stress; Time Factors | 2005 |
Acute depletion of reduced glutathione causes extensive carbonylation of rat brain proteins.
Topics: Animals; Blotting, Western; Brain Chemistry; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Carmustine; Catalase; Deferoxamine; Enzyme Inhibitors; Female; Free Radical Scavengers; Glutathione; Glutathione Peroxidase; Hydroxyl Radical; Immunohistochemistry; In Vitro Techniques; Lipid Peroxidation; Malates; Male; Mitochondria; Nerve Tissue Proteins; Oxidation-Reduction; Oxypurinol; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Subcellular Fractions; Sulfhydryl Compounds; Uncoupling Agents | 2006 |
Effect of desferrioxamine, a strong iron (III) chelator, on 1-methyl-4-phenylpyridinium ion (MPP+)-induced hydroxyl radical generation in the rat striatum.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Cations; Corpus Striatum; Deferoxamine; Dopamine; Extracellular Space; Ferric Compounds; Hydroxyl Radical; Iron Chelating Agents; Male; Microdialysis; Rats; Rats, Wistar | 2006 |
Reactive oxygen species generation in gingival fibroblasts of Down syndrome patients detected by electron spin resonance spectroscopy.
Topics: Adult; Catalase; Cell Culture Techniques; Deferoxamine; Down Syndrome; Electron Spin Resonance Spectroscopy; Female; Fibroblasts; Gingiva; Humans; Hydrogen Peroxide; Hydroxyl Radical; Male; Models, Chemical; Oxidation-Reduction; Oxidative Stress; Periodontitis; Reactive Oxygen Species; Superoxide Dismutase; Superoxides | 2006 |
The effect of metal chelators on the production of hydroxyl radicals in thylakoids.
Topics: Chelating Agents; Deferoxamine; Edetic Acid; Hydroxyl Radical; Light; Pentetic Acid; Pisum sativum; Thylakoids | 2006 |
Neural and hydroxyl radical mechanisms underlying laryngeal airway hyperreactivity induced by laryngeal acid-pepsin insult in anesthetized rats.
Topics: Action Potentials; Ammonia; Animals; Antioxidants; Blood Pressure; Capsaicin; Deferoxamine; Electrophysiology; Free Radical Scavengers; Gastroesophageal Reflux; Hydrogen-Ion Concentration; Hydroxyl Radical; Inflammation; Laryngeal Muscles; Male; Neurons, Afferent; Pepsin A; Rats; Rats, Sprague-Dawley; Respiratory Hypersensitivity; Thiourea | 2006 |
Source-dependent variation in hydroxyl radical production by airborne particulate matter.
Topics: Air Pollutants; Catalase; Chromatography, High Pressure Liquid; Deferoxamine; Dimethyl Sulfoxide; Fluorescence; Hydroxyl Radical; NADP; Oxygen; Particulate Matter; Pentetic Acid | 2007 |
Contribution of the photo-Fenton reaction to hydroxyl radical formation rates in river and rain water samples.
Topics: Deferoxamine; Hydrogen Peroxide; Hydroxyl Radical; Iron; Photochemistry; Rain; Rivers | 2007 |
Potential mechanism for pentachlorophenol-induced carcinogenicity: a novel mechanism for metal-independent production of hydroxyl radicals.
Topics: Benzoquinones; Carcinogens; Cell Line; Chloranil; Deferoxamine; DNA Damage; Free Radical Scavengers; Fungicides, Industrial; Humans; Hydrogen Peroxide; Hydroxyl Radical; Metals; Mutagenicity Tests; Oxidation-Reduction; Pentachlorophenol | 2009 |
Chelation of lysosomal iron protects dopaminergic SH-SY5Y neuroblastoma cells from hydrogen peroxide toxicity by precluding autophagy and Akt dephosphorylation.
Topics: Adenine; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Cell Line, Tumor; Deferoxamine; Free Radicals; Gene Silencing; Humans; Hydrogen Peroxide; Hydroxyl Radical; Lysosomes; Membrane Proteins; Mitochondria; Neuroblastoma; Oncogene Protein v-akt; Oxidants; Phosphorylation; RNA, Small Interfering; Siderophores | 2011 |
Effects of the iron-chelating agent deferoxamine on triethylene glycol dimethacrylate, 2-hydroxylethyl methacrylate, hydrogen peroxide-induced cytotoxicity.
Topics: Animals; Cell Line; Deferoxamine; Dogs; Dose-Response Relationship, Drug; Humans; Hydrogen Peroxide; Hydroxyl Radical; Iron; Materials Testing; Methacrylates; Mice; Oxidants; Polyethylene Glycols; Polymethacrylic Acids; Resins, Synthetic; Siderophores | 2012 |
Profound morphological changes in the erythrocytes and fibrin networks of patients with hemochromatosis or with hyperferritinemia, and their normalization by iron chelators and other agents.
Topics: Adolescent; Adult; Child; Clioquinol; Deferoxamine; Erythrocytes; Female; Ferritins; Fibrin; Hemochromatosis; Humans; Hydroxyl Radical; Iron; Iron Chelating Agents; Male; Microscopy, Electron, Scanning; Middle Aged; Platelet-Rich Plasma; Salicylic Acid; Selenious Acid; Thrombin; Up-Regulation | 2014 |
Nitric oxide induces hypoxia ischemic injury in the neonatal brain via the disruption of neuronal iron metabolism.
Topics: Aconitate Hydratase; Animals; Animals, Newborn; Cell Death; Cell Hypoxia; Culture Media; Deferoxamine; Ferritins; Gene Expression Regulation; Glucose; Hippocampus; Hydroxyl Radical; Hypoxia-Ischemia, Brain; Iron; Microtomy; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Receptors, Transferrin; Tissue Culture Techniques | 2015 |
Hydrogen peroxide causes Vibrio vulnificus bacteriolysis accelerated by sulfonyl fluoride compounds.
Topics: Anti-Infective Agents; Bacteriolysis; Deferoxamine; Hydrogen Peroxide; Hydroxyl Radical; Siderophores; Sulfinic Acids; Vibrio vulnificus | 2015 |
Generation Mechanism of Deferoxamine Radical by Tyrosine-Tyrosinase Reaction.
Topics: Agaricales; Deferoxamine; Electron Transport; Hydroxyl Radical; Monophenol Monooxygenase; Protons; Tyrosine | 2015 |