deferoxamine and d-alpha tocopherol

deferoxamine has been researched along with d-alpha tocopherol in 107 studies

Research

Studies (107)

TimeframeStudies, this research(%)All Research%
pre-199012 (11.21)18.7374
1990's65 (60.75)18.2507
2000's19 (17.76)29.6817
2010's9 (8.41)24.3611
2020's2 (1.87)2.80

Authors

AuthorsStudies
Ayer, DE; Belonga, KL; Braughler, JM; Hall, ED; Houser, DJ; Jacobsen, EJ; Krook, MA; McCall, JM; Palmer, JR; Van Doornik, FJ1
Cantore, M; Ciuffi, M; Da Settimo, F; Failli, P; La Motta, C; Lavecchia, A; Marini, AM; Mugnaini, L; Novellino, E; Salerno, S; Sartini, S; Simorini, F; Taliani, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Hershko, C; Rachmilewitz, EA1
Munkres, KD1
Hirai, S; Kanai, H; Sotomatsu, A; Tanaka, M1
Nagano, N; Nishikori, K; Yagi, M1
Fukazawa, K; Murakami, K; Muto, N; Yamamoto, I1
Hoffer, E; Tabak, A; Taitelman, U; Zonis, Z1
Helfaer, MA; Kirsch, JR; Lange, DG; Traystman, RJ1
Khan, S; O'Brien, PJ; Ramwani, JJ1
Catudioc, JD; Kagan, VE; Packer, L; Safadi, A; Serbinova, EA1
Beuving, LJ; Fleckenstein, AE; Hall, ED; Linseman, KL; Smith, SL1
Houbion, A; Michiels, C; Raes, M; Remacle, J1
Boelsterli, UA; Göldlin, CR1
Hirai, S; Nakano, M; Sotomatsu, A1
Nakano, M; Sakurai, T; Sugioka, K1
Brunk, UT; Marzabadi, MR; Sohal, RS1
Bacon, BR; Britton, RS; Dalton, N; Magiera, CJ; O'Neill, R; Park, CH; Sharma, BK; Smanik, P; Speroff, T1
Reed, DJ; Thomas, CE1
Hatherill, JR; Lutz, MJ; Till, GO; Tourtellotte, WW; Ward, PA1
Cohen, P; Di Monte, D; Sandy, MS; Smith, MT1
Li, MK; Shaw, JF1
Fuller, B; Gower, J; Green, C1
Tiegs, G; Wendel, A; Werner, C1
Braughler, JM; Chase, RL; Duncan, LA; Jacobsen, EJ; McCall, JM; Pregenzer, JF1
Festa, RS1
Sawyer, BC; Slater, TF1
Clark, IA1
Rubin, JJ; Willmore, LJ1
Deby, C; Defraigne, JO; Detry, O; Franssen, C; Lamy, M; Pincemail, J1
Daniels, S; Duncan, CJ1
Anderson, D; Phillips, BJ; Schmezer, P; Yu, TW1
Hoffmann, P; Plews, P; Toraason, M; Wey, H; Woolery, M1
Farber, JL; Gilfor, E; Glascott, PA1
Lightbody, JH; McMaster, D; Tate, S; Trimble, ER; Young, IS1
Defraigne, JO; Detry, O; Franssen, C; Limet, R; Meurisse, M; Pincemail, J2
Defraigne, JO; Detry, O; Franssen, C; Lamy, M; Limet, R; Meurisse, M; Pincemail, J1
Aniya, Y; Daido, A1
Di Giacomo, C; La Delfa, C; Perez-Polo, JR; Renis, M; Russo, A; Sorrenti, V; Vanella, A1
Rafferty, NS; Zigman, S1
Lee, HP; Ong, CN; Shen, HM; Shi, CY1
Itoh, H; Kajiyama, G; Kawasaki, T; Koyama, S; Matsura, T; Nakanishi, T; Shioda, T1
Bianchetti, A; Cini, M; Fariello, RG; Moretti, A1
Borle, AB; Caraceni, P; Rosenblum, ER; Van Thiel, DH1
Anderton, BH; Thomas, SM; Uney, JB1
Blakley, BR; Omara, FO1
Boldyrev, AA; Bulygina, ER; Kurella, EG; Tiulina, OV; Volynskaia, EA1
Herbert, KE; Lunec, J; Struthers, L; Thomas, SM1
Courtiere, A; Molard, F; Reybaud, J1
Ciuffi, M; Franchi-Micheli, S; Mugnai, S; Tarlini, L; Zilletti, L1
Imura, N; Naganuma, A; Nakagawa, I; Suzuki, M1
Guyton, JR; Hughes, H; Karsan, D; Lenz, ML; Mathews, B; Selinger, E; Smith, CV1
Lłvaas, E; Marzabadi, MR1
Crosland, RD1
Nerlich, AG; Schleicher, ED; Wagner, E1
Anthonypillai, V; Bach, PH; Brant, S; Kaler, B; Obatomi, DK1
Lai, CT; Yu, PH1
Cederbaum, AI; Chen, Q; Galleano, M1
Furukawa, Y; Sugiyama, M; Susa, N; Ueno, S1
Hubel, CA; Kagan, VE; Kisin, ER; McLaughlin, MK; Roberts, JM1
Harada, N; Hidaka, H; Kashiwagi, A; Kikkawa, R; Kojima, H; Maegawa, H; Nishio, Y; Takahara, N1
Calzada, C; Lagarde, M; Vericel, E1
Chiu, DT; Huang, TY; Hung, IJ; Liu, TZ; Stern, A; Wei, JS1
Jiang, DH; Lan, J1
Hansen, TW; Knisely, AS; Kocoshis, SA; Reyes, J; Rosh, J; Sigurdsson, L1
Duganzich, DM; Jensen, K; Munday, R; Oliver, JE; Smith, JF; Upreti, GC1
de Groot, H; Rauen, U1
Dailly, E; Tillement, JP; Urien, S1
Bekerecioğlu, M; Ozyazgan, I; Tercan, M1
Collell, M; Dresow, B; Dürken, M; Engelhardt, R; Fischer, R; Nielsen, P; Piga, A; Politis, C; Reller, K1
Furuno, K; Shimomichi, K; Suetsugu, T; Sugihara, N; Tsuruta, Y1
Babenko, NA; Lacort, M; Martín, C; Martínez, R; Ruiz-Larrea, MB1
Klebanov, GI; Lyubitsky, OB; Vasiljeva, OV1
Hershko, C; Konijn, AM; Link, G1
Ametani, MS; Haworth, RA; Southard, JH; Vreugdenhil, PK1
Chen, CC; Chen, CL; Chi, CW; Liu, TY1
Hirano, KI; Ishimura, Y; Kato, Y; Kitajima, M; Kumamoto, Y; Makino, N; Naito, M; Sano, T; Shimazu, M; Suematsu, M; Wakabayashi, G1
Richter-Landsberg, C; Vollgraf, U; Wegner, M1
Alpoim, MC; Fernandes, MA; Geraldes, CF; Oliveira, CR1
Khanna, S; Packer, L; Roy, S; Sen, CK1
Bailey, SM; Reinke, LA1
Baker, RD; Baker, SS; Gupta, A; Li, L; Rao, RK1
Ewing, MM; Philbert, MA; Tjalkens, RB1
Agar, NS; Jone, GL; Zou, CG1
Barberi, I; Cuzzocrea, S; Fulia, F; Gitto, E; Karbownik, M; Manchester, LC; Reiter, RJ; Tan, DX1
Archakov, AI; Karuzina, II; Lisitsa, AV; Petushkova, NA; Zgoda, VG1
Dolay, K; Köksoy, F; Lice, H; Ozşeker, A; Soybir, G; Soybir, N1
Baba, N; Kaneko, T; Matsuo, M; Sasaki, N; Toda, T1
Akalin, N; Balkaya, M; Bolaman, Z; Demir, S; Enli, Y; Kadikoylu, G1
Cederbaum, AI; Fisher, EA; Ginsberg, HN; Pan, M; Williams, KJ; Zhang, YL1
Gol, A; Kadkhodaee, M1
Cho, SI; Chung, HS; Jang, CG; Lee, SK; Lee, SM; Lim, MA; Park, MJ1
Howarth, ES; Venkat-Raman, N; Venkata-Krishnan, RV1
Alberti, D; Coates, T; Evans, P; Giardina, PJ; Harmatz, P; Holland, J; Kwiatkowski, JL; Macklin, EA; Neufeld, EJ; Olivieri, N; Porter, J; Vichinsky, E; Walter, PB1
Blair, IA; Frey, AJ; Harvey, RG; Mangal, D; Park, JH; Penning, TM1
Altunhan, H; Annagür, A; Örs, R; Yüksekkaya, HA1
Leake, DS; Satchell, L1
Baccino, FM; Bonelli, G; Costelli, P; Khadjavi, A; Minero, VG1
Chang, SW; Chung, JH; Kim, EC; Kim, YS; Lee, YM; Noh, K1
Kamau, PW; Loch-Caruso, R; Park, HR1
Ibrahim, MA; Isah, MB1
Caputa, M; Kletkiewicz, H; Mila-Kierzenkowska, C; Nowakowska, A; Rogalska, J; Siejka, A; Woźniak, A1
Hara, S; Ito, J; Kamata, R; Karasawa, T; Kimura, H; Komada, T; Kuwata, H; Mizuta, K; Nakagawa, K; Sakuma, Y; Sampilvanjil, A; Sata, N; Takahashi, M; Watanabe, S; Yamada, N1
Cai, Z; Cheng, W; Ding, J; Kuang, Y; Li, M; Li, Y; Mei, S; Ni, Z; Song, D; Sun, S; Yu, C; Yu, J; Zhou, L1

Reviews

5 review(s) available for deferoxamine and d-alpha tocopherol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Evidence for free radical mechanisms of brain injury resulting from ischemia/reperfusion-induced events.
    Journal of neurotrauma, 1992, Volume: 9 Suppl 1

    Topics: Animals; Brain; Brain Injuries; Brain Ischemia; Deferoxamine; Free Radical Scavengers; Free Radicals; Leukocytes; Reperfusion Injury; Vitamin E

1992
Modern management of thalassemia.
    Pediatric annals, 1985, Volume: 14, Issue:9

    Topics: Adolescent; Arrhythmias, Cardiac; Ascorbic Acid; Blood Transfusion; Child; Cholelithiasis; Deferoxamine; Endocrine System Diseases; Female; Folic Acid; Growth Disorders; Heart Failure; Hematopoiesis; Humans; Iron; Leg Ulcer; Liver Diseases; Male; Pericarditis; Splenectomy; Thalassemia; Vitamin E

1985
Desferrioxamine and vitamin E protect against iron and MPTP-induced neurodegeneration in mice.
    Journal of neural transmission (Vienna, Austria : 1996), 1997, Volume: 104, Issue:4-5

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Diseases; Corpus Striatum; Deferoxamine; Dopamine; Female; Glutathione; Glutathione Disulfide; Hydroxyl Radical; Iron; Lipid Peroxides; Male; Mice; Nerve Degeneration; Osmolar Concentration; Vitamin E

1997
The role of antioxidants treatment on the pathogenesis of malarial infections: a review.
    Parasitology research, 2014, Volume: 113, Issue:3

    Topics: Acetylcysteine; Antimalarials; Antioxidants; Ascorbic Acid; Deferoxamine; Folic Acid; Humans; Malaria; Oxidative Stress; Plasmodium; Vitamin E

2014

Trials

1 trial(s) available for deferoxamine and d-alpha tocopherol

ArticleYear
Inflammation and oxidant-stress in beta-thalassemia patients treated with iron chelators deferasirox (ICL670) or deferoxamine: an ancillary study of the Novartis CICL670A0107 trial.
    Haematologica, 2008, Volume: 93, Issue:6

    Topics: Adolescent; Adult; Ascorbic Acid; Benzoates; beta-Thalassemia; C-Reactive Protein; Child; Deferasirox; Deferoxamine; Female; Humans; Iron Chelating Agents; Lipid Peroxidation; Male; Oxidants; Oxidative Stress; Triazoles; Vitamin E

2008

Other Studies

101 other study(ies) available for deferoxamine and d-alpha tocopherol

ArticleYear
Novel 21-aminosteroids that inhibit iron-dependent lipid peroxidation and protect against central nervous system trauma.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:4

    Topics: Amines; Animals; Antioxidants; Craniocerebral Trauma; Drug Evaluation, Preclinical; Lipid Peroxidation; Male; Mice; Pregnatrienes; Rats; Spinal Injuries; Steroids; Structure-Activity Relationship

1990
Pyrido[1,2-a]pyrimidin-4-one derivatives as a novel class of selective aldose reductase inhibitors exhibiting antioxidant activity.
    Journal of medicinal chemistry, 2007, Oct-04, Volume: 50, Issue:20

    Topics: Aldehyde Reductase; Animals; Antioxidants; Binding Sites; Catechols; Humans; Kidney; Lens, Crystalline; Models, Molecular; Pyridines; Pyrimidines; Rats; Structure-Activity Relationship; Tissue Extracts

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
The inhibitory effect of vitamin E on desferrioxamine-induced iron excretion in rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1976, Volume: 152, Issue:2

    Topics: Animals; Deferoxamine; Female; Ferritins; Iron; Liver; Rats; Spleen; Thalassemia; Vitamin E

1976
Selection and analysis of superoxide dismutase mutants of Neurospora.
    Free radical biology & medicine, 1992, Volume: 13, Issue:4

    Topics: Deferoxamine; Hot Temperature; Isoenzymes; Mitochondria; Mutation; Neurospora; Oxygen; Paraquat; Phenotype; Superoxide Dismutase; Vitamin E

1992
Combined histochemical and biochemical demonstration of nigral vulnerability to lipid peroxidation induced by dopa and iron.
    Neuroscience letters, 1992, Jun-08, Volume: 140, Issue:1

    Topics: Adenosine Diphosphate; Animals; Caudate Nucleus; Deferoxamine; Dihydroxyphenylalanine; Iron; Iron Chelating Agents; Lipid Peroxidation; Male; Organ Specificity; Putamen; Rats; Rats, Wistar; Substantia Nigra; Vitamin E; Vitamin E Deficiency

1992
Protective effects of antioxidants on paraquat-induced acute renal failure in mice.
    Japanese journal of pharmacology, 1992, Volume: 59, Issue:4

    Topics: Acute Kidney Injury; Animals; Antioxidants; Blood Urea Nitrogen; Creatinine; Deferoxamine; Electrolytes; Male; Mice; Mice, Inbred Strains; Paraquat; Reactive Oxygen Species; Thiourea; Vitamin E

1992
Comparison of ascorbic acid and ascorbic acid 2-O-alpha-glucoside on the cytotoxicity and bioavailability to low density cultures of fibroblasts.
    Biochemical pharmacology, 1992, Dec-01, Volume: 44, Issue:11

    Topics: Animals; Ascorbic Acid; Biological Availability; Catalase; Cell Count; Cell Survival; Cells, Cultured; Chick Embryo; Collagen; Deferoxamine; Female; Fibroblasts; Humans; Infant; Intracellular Fluid; Kinetics; Reactive Oxygen Species; Skin; Vitamin E

1992
The administration of desferrioxamine to paraquat-intoxicated rats.
    Veterinary and human toxicology, 1992, Volume: 34, Issue:4

    Topics: Animals; Deferoxamine; Iron; Male; Oxidation-Reduction; Paraquat; Rats; Rats, Inbred Strains; Vitamin E

1992
Hepatocyte toxicity of mechlorethamine and other alkylating anticancer drugs. Role of lipid peroxidation.
    Biochemical pharmacology, 1992, May-08, Volume: 43, Issue:9

    Topics: Alkylating Agents; Animals; Antioxidants; Butylated Hydroxyanisole; Cell Death; Cyclic N-Oxides; Deferoxamine; Glutathione; Lipid Peroxidation; Liver; Male; Malondialdehyde; Mechlorethamine; Rats; Rats, Inbred Strains; Vitamin E

1992
NADPH-dependent inhibition of lipid peroxidation in rat liver microsomes.
    Biochemical and biophysical research communications, 1992, Jul-15, Volume: 186, Issue:1

    Topics: Animals; Azo Compounds; Chromans; Chromatography, High Pressure Liquid; Deferoxamine; Kinetics; Lipid Peroxidation; Male; Microsomes, Liver; Models, Biological; NADP; Nitriles; Oxidation-Reduction; Rats; Rats, Inbred Strains; Vitamin E; Vitamin E Deficiency

1992
Comparison of the efficacy of mechanistically different antioxidants in the rat hemorrhagic shock model.
    Circulatory shock, 1991, Volume: 35, Issue:4

    Topics: Animals; Antioxidants; Chromans; Deferoxamine; Disease Models, Animal; Ibuprofen; Lipid Peroxidation; Male; Oxypurinol; Piperazines; Pregnatrienes; Rats; Rats, Inbred Strains; Shock, Hemorrhagic; Vitamin E; Xanthine Oxidase

1991
Association of antioxidant systems in the protection of human fibroblasts against oxygen derived free radicals.
    Free radical research communications, 1991, Volume: 14, Issue:5-6

    Topics: Antioxidants; Catalase; Cell Survival; Cells, Cultured; Deferoxamine; Drug Synergism; Fibroblasts; Free Radical Scavengers; Free Radicals; Glutathione Peroxidase; Humans; Microinjections; Oxygen; Superoxide Dismutase; Vitamin E

1991
Reactive oxygen species and non-peroxidative mechanisms of cocaine-induced cytotoxicity in rat hepatocyte cultures.
    Toxicology, 1991, Volume: 69, Issue:1

    Topics: Animals; Cell Survival; Cells, Cultured; Cocaine; Deferoxamine; Drug Interactions; Glutathione; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Male; Maleates; Oxygen; Polyethylene Glycols; Rats; Rats, Inbred Strains; Vitamin E

1991
Phospholipid peroxidation induced by the catechol-Fe3+(Cu2+) complex: a possible mechanism of nigrostriatal cell damage.
    Archives of biochemistry and biophysics, 1990, Volume: 283, Issue:2

    Topics: Animals; Cations; Ceruloplasmin; Corpus Striatum; Deferoxamine; Dihydroxyphenylalanine; Fatty Acids; Ferric Compounds; Kinetics; Lipid Peroxidation; Oxygen Consumption; Phospholipids; Substantia Nigra; Vitamin E

1990
O2- generation and lipid peroxidation during the oxidation of a glycated polypeptide, glycated polylysine, in the presence of iron-ADP.
    Biochimica et biophysica acta, 1990, Mar-12, Volume: 1043, Issue:1

    Topics: Adenosine Diphosphate; Deferoxamine; Ferric Compounds; Glycosylation; Hydrogen-Ion Concentration; Iodine; Iron; Lipid Peroxidation; Liposomes; Luminescent Measurements; Oxidation-Reduction; Oxygen Consumption; Polylysine; Spectrophotometry; Superoxide Dismutase; Superoxides; Thiobarbiturates; Vitamin E

1990
Effect of alpha-tocopherol and some metal chelators on lipofuscin accumulation in cultured neonatal rat cardiac myocytes.
    Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology, 1990, Volume: 2, Issue:6

    Topics: Animals; Animals, Newborn; Antioxidants; Cells, Cultured; Chelating Agents; Deferoxamine; Lipofuscin; Myocardium; Oxygen; Pentetic Acid; Rats; Rats, Inbred Strains; Vitamin E

1990
Prevention of hepatocyte injury and lipid peroxidation by iron chelators and alpha-tocopherol in isolated iron-loaded rat hepatocytes.
    Hepatology (Baltimore, Md.), 1990, Volume: 12, Issue:1

    Topics: Animals; Apoproteins; Cell Survival; Cells, Cultured; Deferoxamine; Iron; Lipid Peroxidation; Liver; Male; Malondialdehyde; Microscopy, Electron; Rats; Rats, Inbred Strains; Reference Values; Transferrin; Vitamin E

1990
Effect of extracellular Ca++ omission on isolated hepatocytes. II. Loss of mitochondrial membrane potential and protection by inhibitors of uniport Ca++ transduction.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:2

    Topics: Animals; Calcium; Cells, Cultured; Deferoxamine; Glutathione; Kinetics; L-Lactate Dehydrogenase; Lanthanum; Liver; Male; Malondialdehyde; Membrane Potentials; Mitochondria, Liver; Rats; Rats, Inbred Strains; Ruthenium; Ruthenium Red; Submitochondrial Particles; Vitamin E

1988
Lipid peroxidation and acute lung injury after thermal trauma to skin. Evidence of a role for hydroxyl radical.
    The American journal of pathology, 1985, Volume: 119, Issue:3

    Topics: Animals; Burns; Capillary Permeability; Chelating Agents; Deferoxamine; Dimethyl Sulfoxide; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Lipid Metabolism; Lipid Peroxides; Lung; Lung Diseases; Neutrophils; Rats; Rats, Inbred Strains; Skin; Vitamin E

1985
Role of active oxygen in paraquat and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) cytotoxicity.
    Basic life sciences, 1988, Volume: 49

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antioxidants; Carmustine; Cell Survival; Cells, Cultured; Deferoxamine; Free Radicals; Lipid Peroxidation; Liver; Paraquat; Phenylenediamines; Pyridines; Rats; Reference Values; Vitamin E

1988
Free radical scavenger therapy in transplant rejection.
    Transplantation proceedings, 1987, Volume: 19, Issue:1 Pt 2

    Topics: Allopurinol; Animals; Deferoxamine; Free Radicals; Graft Rejection; Graft Survival; Heart Transplantation; Rats; Rats, Inbred Strains; Superoxide Dismutase; Vitamin E

1987
Lipid peroxidation in the cortex and medulla of rabbit kidneys subjected to cold ischaemia and the value of protective agents.
    Free radical research communications, 1987, Volume: 3, Issue:1-5

    Topics: Animals; Cold Temperature; Deferoxamine; Imidazoles; In Vitro Techniques; Indomethacin; Ischemia; Kidney; Kidney Cortex; Kidney Medulla; Lipid Peroxidation; Male; Rabbits; Thromboxane-A Synthase; Vitamin E

1987
Evidence for the involvement of a reperfusion injury in galactosamine/endotoxin-induced hepatitis in mice.
    Biochemical pharmacology, 1987, Aug-15, Volume: 36, Issue:16

    Topics: Allopurinol; Animals; Deferoxamine; Drug Interactions; Endotoxins; Galactosamine; Hepatitis, Animal; Liver; Male; Mice; Perfusion; Salmonella; Vitamin E

1987
Novel 21-amino steroids as potent inhibitors of iron-dependent lipid peroxidation.
    The Journal of biological chemistry, 1987, Aug-05, Volume: 262, Issue:22

    Topics: Animals; Brain; Butylated Hydroxytoluene; Cell Membrane; Deferoxamine; Iron; Lipid Peroxides; Pregnatrienes; Rats; Synaptosomes; Thiobarbiturates; Vitamin E

1987
The stimulatory effects of carbon tetrachloride on peroxidative reactions in rat liver fractions in vitro. Inhibitory effects of free-radical scavengers and other agents.
    The Biochemical journal, 1971, Volume: 123, Issue:5

    Topics: Aldehydes; Aniline Compounds; Animals; Carbon Tetrachloride; Deferoxamine; Edetic Acid; Female; Gallic Acid; Glycols; In Vitro Techniques; Inosine; Lipid Metabolism; Liver; Malonates; Microsomes, Liver; Peroxides; Polyethylenes; Promethazine; Rats; Vitamin E

1971
Proposed treatment of Duchenne muscular dystrophy with desferrioxamine.
    Medical hypotheses, 1984, Volume: 13, Issue:2

    Topics: Animals; Deferoxamine; Genes, Recessive; Genetic Linkage; Humans; Iron; Membrane Lipids; Muscles; Muscular Dystrophies; Muscular Dystrophy, Animal; Oxidation-Reduction; Vitamin E; Vitamin E Deficiency

1984
Prevention of iron-induced epileptiform discharges in rats by treatment with antiperoxidants.
    Experimental neurology, 1980, Volume: 67, Issue:3

    Topics: Animals; Cerebral Cortex; Deferoxamine; Electroencephalography; Evoked Potentials; Ferrous Compounds; Rats; Seizures; Selenium; Vitamin E

1980
Antioxidant defense and free radical production in a rabbit model of kidney ischemia-reperfusion.
    Transplantation proceedings, 1995, Volume: 27, Issue:5

    Topics: Animals; Antioxidants; Catalase; Deferoxamine; Electron Spin Resonance Spectroscopy; Free Radicals; Glutathione; Glutathione Peroxidase; Ischemia; Kidney; Kinetics; Rabbits; Reference Values; Reperfusion; Siderophores; Time Factors; Vitamin E

1995
Are oxygen radicals implicated in the calcium paradox of the rat heart?
    Journal of cardiovascular pharmacology, 1994, Volume: 23, Issue:1

    Topics: Animals; Caffeine; Calcium; Catalase; Creatine Kinase; Deferoxamine; Dinitrophenols; Free Radical Scavengers; Free Radicals; In Vitro Techniques; Mannitol; Myocardial Reperfusion Injury; Myocardium; Oxygen; Rats; Rats, Wistar; Superoxide Dismutase; Thiourea; Vitamin E

1994
The effect of various antioxidants and other modifying agents on oxygen-radical-generated DNA damage in human lymphocytes in the COMET assay.
    Mutation research, 1994, May-01, Volume: 307, Issue:1

    Topics: Adult; Antioxidants; Apoproteins; Ascorbic Acid; Bleomycin; Catalase; Cells, Cultured; Deferoxamine; DNA Damage; Drug Interactions; Female; Ferrous Compounds; Humans; Hydrogen Peroxide; Lymphocytes; Male; Mannitol; Mutagenicity Tests; Reactive Oxygen Species; Silymarin; Smoking; Superoxide Dismutase; Transferrin; Vitamin E

1994
Arachidonic acid supplementation enhances hydrogen peroxide induced oxidative injury of neonatal rat cardiac myocytes.
    Cardiovascular research, 1995, Volume: 29, Issue:5

    Topics: Animals; Arachidonic Acid; Deferoxamine; Fatty Acids; Hydrogen Peroxide; In Vitro Techniques; L-Lactate Dehydrogenase; Lipid Peroxidation; Myocardium; Oxidative Stress; Phospholipids; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances; Vitamin E

1995
Relationship of the metabolism of vitamins C and E in cultured hepatocytes treated with tert-butyl hydroperoxide.
    Molecular pharmacology, 1995, Volume: 48, Issue:1

    Topics: Animals; Antioxidants; Ascorbic Acid; Cells, Cultured; Deferoxamine; DNA Damage; DNA, Single-Stranded; Lipid Peroxidation; Liver; Male; Peroxides; Phenylenediamines; Rats; Rats, Sprague-Dawley; tert-Butylhydroperoxide; Vitamin E

1995
The effects of desferrioxamine and ascorbate on oxidative stress in the streptozotocin diabetic rat.
    Free radical biology & medicine, 1995, Volume: 18, Issue:5

    Topics: Animals; Ascorbic Acid; Blood Glucose; Cholesterol; Copper; Deferoxamine; Diabetes Mellitus, Experimental; Erythrocyte Membrane; Glycated Hemoglobin; Glycated Serum Albumin; Glycation End Products, Advanced; Humans; Insulin; Insulin, Regular, Pork; Iron; Liver; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Recombinant Proteins; Reference Values; Serum Albumin; Triglycerides; Vitamin A; Vitamin E

1995
Preservation of cortical microcirculation after kidney ischemia-reperfusion: value of an iron chelator.
    Annals of vascular surgery, 1994, Volume: 8, Issue:5

    Topics: Animals; Constriction; Deferoxamine; Ischemia; Kidney Cortex; Laser-Doppler Flowmetry; Microcirculation; Models, Biological; Rabbits; Renal Circulation; Reperfusion; Reperfusion Injury; Vitamin E

1994
Direct evidence of free radical production after ischaemia and reperfusion and protective effect of desferrioxamine: ESR and vitamin E studies.
    European journal of vascular surgery, 1994, Volume: 8, Issue:5

    Topics: Animals; Deferoxamine; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Free Radicals; Ischemia; Kidney; Kidney Cortex; Lipid Peroxidation; Rabbits; Reactive Oxygen Species; Reperfusion Injury; Vitamin E

1994
Activation of microsomal glutathione S-transferase in tert-butyl hydroperoxide-induced oxidative stress of isolated rat liver.
    Japanese journal of pharmacology, 1994, Volume: 66, Issue:1

    Topics: Animals; Deferoxamine; Dithiothreitol; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Ethylmaleimide; Glutathione Peroxidase; Glutathione Transferase; Immunoblotting; In Vitro Techniques; Male; Microsomes, Liver; Oxidants; Oxidation-Reduction; Oxidative Stress; Peroxides; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds; tert-Butylhydroperoxide; Vitamin E

1994
Lipid peroxidation and survival in rats following cerebral post-ischaemic reperfusion: effect of drugs with different molecular mechanisms.
    Drugs under experimental and clinical research, 1994, Volume: 20, Issue:5

    Topics: Allopurinol; Animals; Antioxidants; Brain Ischemia; Deferoxamine; Diltiazem; Lipid Peroxidation; Male; Rats; Rats, Wistar; Reperfusion; Reperfusion Injury; Verapamil; Vitamin E

1994
Effects of near UV radiation and antioxidants on the response of dogfish (Mustelus canis) lens to elevated H2O2.
    Comparative biochemistry and physiology. Physiology, 1994, Volume: 109, Issue:2

    Topics: Animals; Antioxidants; Catalase; Deferoxamine; Dogfish; Hydrogen Peroxide; In Vitro Techniques; Lens, Crystalline; Ultraviolet Rays; Vitamin E

1994
Aflatoxin B1-induced lipid peroxidation in rat liver.
    Toxicology and applied pharmacology, 1994, Volume: 127, Issue:1

    Topics: Aflatoxin B1; Alanine Transaminase; Analysis of Variance; Animals; Aspartate Aminotransferases; Deferoxamine; Dose-Response Relationship, Drug; Lipid Peroxidation; Liver; Male; Malondialdehyde; Rats; Rats, Inbred F344; Selenium; Vitamin E

1994
Iron ion induces mitochondrial DNA damage in HTC rat hepatoma cell culture--role of antioxidants in mitochondrial DNA protection from oxidative stresses.
    Archives of biochemistry and biophysics, 1994, Aug-15, Volume: 313, Issue:1

    Topics: Animals; Antioxidants; Cell Line; Cells, Cultured; Deferoxamine; DNA Damage; DNA, Mitochondrial; In Vitro Techniques; Iron; Liver; Liver Neoplasms, Experimental; Oxidation-Reduction; Rats; Ubiquinone; Vitamin E

1994
Studies on lipid peroxidation in the rat brain.
    Neurochemical research, 1994, Volume: 19, Issue:3

    Topics: Allopurinol; Animals; Antioxidants; Brain; Chromans; Deferoxamine; Ferrous Compounds; Kinetics; Lipid Peroxidation; Male; Malondialdehyde; Oxazines; Piperazines; Rats; Rats, Wistar; Vitamin E

1994
Reoxygenation injury in isolated rat hepatocytes: relation to oxygen free radicals and lipid peroxidation.
    The American journal of physiology, 1994, Volume: 266, Issue:5 Pt 1

    Topics: Acridines; Allopurinol; Animals; Antimycin A; Cell Hypoxia; Cells, Cultured; Deferoxamine; Free Radicals; Horseradish Peroxidase; Hydrogen Peroxide; Kinetics; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Luminescent Measurements; Luminol; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; Regression Analysis; Superoxides; Time Factors; Vitamin E

1994
Changes in heat shock protein 70 and ubiquitin mRNA levels in C1300 N2A mouse neuroblastoma cells following treatment with iron.
    Journal of neurochemistry, 1993, Volume: 60, Issue:2

    Topics: Animals; Biological Transport; Blotting, Northern; Cell Survival; Deferoxamine; Heat-Shock Proteins; HeLa Cells; Humans; Iron; L-Lactate Dehydrogenase; Lysosomes; Mice; Mitochondria; Neuroblastoma; Neutral Red; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured; Ubiquitins; Vitamin E

1993
Vitamin E is protective against iron toxicity and iron-induced hepatic vitamin E depletion in mice.
    The Journal of nutrition, 1993, Volume: 123, Issue:10

    Topics: Animals; Chemical and Drug Induced Liver Injury; Deferoxamine; Diet; Iron; Liver; Liver Diseases; Male; Mice; Organ Size; Vitamin E; Vitamin E Deficiency

1993
[The effect of hydrogen peroxide and hypochlorite on brain Na,K-ATPase activity].
    Biokhimiia (Moscow, Russia), 1995, Volume: 60, Issue:10

    Topics: Animals; Antioxidants; Brain; Butylated Hydroxytoluene; Carnosine; Cattle; Deferoxamine; Hydrogen Peroxide; Hypochlorous Acid; Sodium-Potassium-Exchanging ATPase; Vitamin E

1995
Immunodetection of UV-induced DNA damage in a neuronal cell line.
    Biochemical Society transactions, 1995, Volume: 23, Issue:3

    Topics: Antibodies; Antioxidants; Cell Line; Deferoxamine; DNA; DNA Damage; Humans; Neurons; Reactive Oxygen Species; Siderophores; Ultraviolet Rays; Vitamin E

1995
Differential effects of in vitro peroxidation on peripheral- and central-type benzodiazepine receptors. Protection by diverse antioxidants.
    Biochemical pharmacology, 1995, Nov-27, Volume: 50, Issue:11

    Topics: Animals; Antioxidants; Ascorbic Acid; Benzodiazepinones; Brain; Cell Membrane; Chromans; Deferoxamine; Edetic Acid; Ferrous Compounds; Flunitrazepam; Hypolipidemic Agents; Lipid Peroxidation; Liver; Malondialdehyde; Receptors, GABA-A; Rutin; Vitamin E

1995
Hemoglobin affects lipid peroxidation and prostaglandin E2 formation in rat corticocerebral tissues in vitro.
    Biochemical pharmacology, 1996, Jul-12, Volume: 52, Issue:1

    Topics: Animals; Cerebral Cortex; Cyclooxygenase Inhibitors; Deferoxamine; Dinoprostone; Free Radical Scavengers; Hemoglobins; In Vitro Techniques; Indomethacin; Iron Chelating Agents; Lipid Peroxidation; Male; Penicillamine; Rats; Rats, Wistar; Vitamin E

1996
Enhancement of paraquat toxicity by glutathione depletion in mice in vivo and in vitro.
    The Journal of toxicological sciences, 1995, Volume: 20, Issue:5

    Topics: Animals; Buthionine Sulfoximine; Cells, Cultured; Deferoxamine; Glutathione; Lipid Peroxidation; Male; Mice; Paraquat; Vitamin E

1995
Toxicity of oxidized low density lipoproteins for vascular smooth muscle cells and partial protection by antioxidants.
    Atherosclerosis, 1995, Volume: 118, Issue:2

    Topics: Animals; Antioxidants; Aorta; Butylated Hydroxytoluene; Cell Death; Cells, Cultured; Copper; Culture Media; Deferoxamine; Enzyme Inhibitors; Hydroxycholesterols; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ketocholesterols; Lipid Peroxidation; Lipoproteins, LDL; Lovastatin; Mevalonic Acid; Muscle, Smooth, Vascular; Oxidation-Reduction; Probucol; Swine; Thiobarbituric Acid Reactive Substances; Vitamin E

1995
Spermine prevent iron accumulation and depress lipofuscin accumulation in cultured myocardial cells.
    Free radical biology & medicine, 1996, Volume: 21, Issue:3

    Topics: Animals; Animals, Newborn; Antioxidants; Cells, Cultured; Deferoxamine; Iron; Iron Chelating Agents; Lipofuscin; Myocardium; Oxidative Stress; Rats; Rats, Sprague-Dawley; Spermine; Vitamin E

1996
Action of reactive oxygen species and their antagonists on twitch tension of the rat phrenic nerve-diaphragm.
    Pharmacology & toxicology, 1995, Volume: 77, Issue:3

    Topics: Analysis of Variance; Animals; Catalase; Deferiprone; Deferoxamine; Diaphragm; Free Radical Scavengers; Iron Chelating Agents; Male; Neuromuscular Junction; Phrenic Nerve; Pyridones; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase; Thiourea; Tiopronin; Vitamin E

1995
Increased accumulation of the glycoxidation product N(epsilon)-(carboxymethyl)lysine in human tissues in diabetes and aging.
    The Journal of clinical investigation, 1997, Feb-01, Volume: 99, Issue:3

    Topics: Adult; Aged; Aging; Antibodies; Arteries; Arteriosclerosis; Biomarkers; Blood Proteins; Catalase; Child; Deferoxamine; Diabetes Mellitus; Enzyme-Linked Immunosorbent Assay; Epitopes; Female; Fetus; Foam Cells; Guanidines; Humans; Immunohistochemistry; Intervertebral Disc; Intestinal Mucosa; Kidney; Lung; Lysine; Middle Aged; Molecular Structure; Myocardium; Oxidation-Reduction; Oxidative Stress; Pregnancy; Skin; Superoxide Dismutase; Thioctic Acid; Time Factors; Vitamin E

1997
Reduced susceptibility of renal slices to oxidative damage.
    Biochemical Society transactions, 1997, Volume: 25, Issue:1

    Topics: Animals; Antioxidants; Ascorbic Acid; Cell Survival; Deferoxamine; Glutathione; In Vitro Techniques; Kidney Cortex; Kinetics; L-Lactate Dehydrogenase; Male; Mesna; Oxidative Stress; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Vitamin E

1997
Dopamine- and L-beta-3,4-dihydroxyphenylalanine hydrochloride (L-Dopa)-induced cytotoxicity towards catecholaminergic neuroblastoma SH-SY5Y cells. Effects of oxidative stress and antioxidative factors.
    Biochemical pharmacology, 1997, Feb-07, Volume: 53, Issue:3

    Topics: Ascorbic Acid; Catalase; Cell Survival; Deferoxamine; Dopamine; Levodopa; Lipid Peroxidation; Neuroblastoma; Oxidative Stress; Superoxide Dismutase; Tumor Cells, Cultured; Vitamin E

1997
Cytotoxicity and apoptosis produced by arachidonic acid in Hep G2 cells overexpressing human cytochrome P4502E1.
    The Journal of biological chemistry, 1997, Jun-06, Volume: 272, Issue:23

    Topics: alpha-Tocopherol; Antioxidants; Apoptosis; Ascorbic Acid; Aspirin; Carcinoma, Hepatocellular; Cell Survival; Chromans; Cytochrome P-450 CYP2E1; Deferoxamine; Humans; L-Lactate Dehydrogenase; Liver Neoplasms; Oleic Acid; Phenylenediamines; Propyl Gallate; Proto-Oncogene Proteins c-bcl-2; Recombinant Proteins; Transfection; Tumor Cells, Cultured; Vitamin E

1997
Protective effect of deferoxamine on chromium (VI)-induced DNA single-strand breaks, cytotoxicity, and lipid peroxidation in primary cultures of rat hepatocytes.
    Archives of toxicology, 1997, Volume: 71, Issue:6

    Topics: Alkaline Phosphatase; Animals; Antidotes; Ascorbic Acid; Caustics; Cells, Cultured; Deferoxamine; DNA Damage; DNA, Single-Stranded; Dose-Response Relationship, Drug; Glutathione; Glutathione Peroxidase; Glutathione Reductase; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Male; Malondialdehyde; Potassium Dichromate; Rats; Rats, Wistar; Superoxide Dismutase; Vitamin E

1997
Increased ascorbate radical formation and ascorbate depletion in plasma from women with preeclampsia: implications for oxidative stress.
    Free radical biology & medicine, 1997, Volume: 23, Issue:4

    Topics: Adult; Ascorbic Acid; Chromatography, High Pressure Liquid; Deferoxamine; Electron Spin Resonance Spectroscopy; Female; Free Radicals; Humans; Iron Chelating Agents; Oxidative Stress; Pre-Eclampsia; Pregnancy; Sulfhydryl Compounds; Vitamin E

1997
Oxidized lipoproteins found in patients with NIDDM stimulate radical-induced monocyte chemoattractant protein-1 mRNA expression in cultured human endothelial cells.
    Diabetologia, 1997, Volume: 40, Issue:6

    Topics: Antioxidants; Cells, Cultured; Chemokine CCL2; Deferoxamine; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; Humans; Lipoproteins; Male; Middle Aged; Oxidation-Reduction; Probucol; Reference Values; Regression Analysis; RNA, Messenger; Transcription, Genetic; Umbilical Veins; Vitamin E

1997
Low concentrations of lipid hydroperoxides prime human platelet aggregation specifically via cyclo-oxygenase activation.
    The Biochemical journal, 1997, Jul-15, Volume: 325 ( Pt 2)

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Arachidonic Acid; Aspirin; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Deferoxamine; Enzyme Activation; Fatty Acids, Unsaturated; Humans; Hydrazines; Hydrogen Peroxide; Leukotrienes; Lipid Peroxides; Oligopeptides; Peroxides; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; tert-Butylhydroperoxide; Thromboxane B2; Vitamin E

1997
Hemin-induced membrane sulfhydryl oxidation: possible involvement of thiyl radicals.
    Free radical research, 1997, Volume: 27, Issue:1

    Topics: Deferoxamine; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Erythrocytes; Free Radicals; Glutathione; Hemin; Humans; Lipid Peroxidation; Mercaptoethanol; Oxidation-Reduction; Sulfhydryl Compounds; Thiobarbituric Acid Reactive Substances; Vitamin E

1997
Neonatal hemochromatosis: outcomes of pharmacologic and surgical therapies.
    Journal of pediatric gastroenterology and nutrition, 1998, Volume: 26, Issue:1

    Topics: Acetylcysteine; Alprostadil; Antioxidants; Chelating Agents; Deferoxamine; Hemochromatosis; Humans; Infant, Newborn; Liver Transplantation; Retrospective Studies; Selenium; Treatment Outcome; Vitamin E

1998
Motility of ram spermatozoa during storage in a chemically-defined diluent containing antioxidants.
    Animal reproduction science, 1997, Volume: 48, Issue:2-4

    Topics: Animals; Antioxidants; Butylated Hydroxyanisole; Catalase; Cryopreservation; Cryoprotective Agents; Deferoxamine; Male; Propyl Gallate; Semen Preservation; Sheep; Sperm Motility; Spermatozoa; Vitamin E

1997
Cold-induced release of reactive oxygen species as a decisive mediator of hypothermia injury to cultured liver cells.
    Free radical biology & medicine, 1998, Volume: 24, Issue:7-8

    Topics: 2,2'-Dipyridyl; Animals; Cell Hypoxia; Cells, Cultured; Coculture Techniques; Cold Temperature; Cyclic N-Oxides; Deferoxamine; Dimethyl Sulfoxide; Endothelium; Free Radical Scavengers; Hypothermia; Lipid Peroxidation; Liver; Rats; Reactive Oxygen Species; Silymarin; Thiobarbituric Acid Reactive Substances; Vitamin E

1998
Chain-breaking antioxidants and ferriheme-bound drugs are synergistic inhibitors of erythrocyte membrane peroxidation.
    Free radical research, 1998, Volume: 28, Issue:2

    Topics: Adult; Amidines; Antioxidants; Ascorbic Acid; Chloroquine; Deferoxamine; Drug Synergism; Erythrocyte Membrane; Fatty Acids; Female; Hemin; Humans; Linoleic Acid; Lipid Peroxidation; Male; Membrane Lipids; Oxidation-Reduction; Oxygen Consumption; Oxyhemoglobins; Probucol; Pyridines; Reperfusion Injury; Vitamin E

1998
The effect of Gingko biloba extract (Egb 761) as a free radical scavenger on the survival of skin flaps in rats. A comparative study.
    Scandinavian journal of plastic and reconstructive surgery and hand surgery, 1998, Volume: 32, Issue:2

    Topics: Animals; Antioxidants; Ascorbic Acid; Deferoxamine; Flavonoids; Free Radical Scavengers; Ginkgo biloba; Graft Survival; Plant Extracts; Rats; Rats, Sprague-Dawley; Surgical Flaps; Vitamin E

1998
Iron overload and antioxidant status in patients with beta-thalassemia major.
    Annals of the New York Academy of Sciences, 1998, Jun-30, Volume: 850

    Topics: Antioxidants; Ascorbic Acid; beta-Thalassemia; Deferoxamine; Humans; Iron; Iron Chelating Agents; Liver; Transferrin; Vitamin A; Vitamin E

1998
Lipid peroxidation induced by adriamycin in linolenic acid-loaded cultured hepatocytes.
    Pharmacology & toxicology, 1998, Volume: 83, Issue:4

    Topics: 7-Alkoxycoumarin O-Dealkylase; alpha-Linolenic Acid; Animals; Antibiotics, Antineoplastic; Antioxidants; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Deferoxamine; Dose-Response Relationship, Drug; Doxorubicin; Enzyme Inhibitors; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Male; Malondialdehyde; Phenylenediamines; Proadifen; Rats; Rats, Wistar; Vitamin E

1998
Inhibition by estrogens of the oxidant-mediated mobilization of arachidonic acid in hepatocytes.
    Journal of physiology and biochemistry, 1998, Volume: 54, Issue:2

    Topics: Animals; Arachidonic Acid; Carbon Radioisotopes; Cells, Cultured; Chelating Agents; Deferoxamine; Dose-Response Relationship, Drug; Estrogens; Iron; Lipid Peroxidation; Liver; Male; Oxidants; Phospholipases A; Phospholipases A2; Rats; Rats, Sprague-Dawley; tert-Butylhydroperoxide; Vitamin E

1998
Effect of antioxidants on the kinetics of chain lipid peroxidation in liposomes.
    Membrane & cell biology, 1998, Volume: 12, Issue:2

    Topics: Animals; Antioxidants; Ascorbic Acid; beta Carotene; Chick Embryo; Deferoxamine; Edetic Acid; Kinetics; Lipid Peroxidation; Liposomes; Luminescent Measurements; Rutin; Vitamin E

1998
Cardioprotective effect of alpha-tocopherol, ascorbate, deferoxamine, and deferiprone: mitochondrial function in cultured, iron-loaded heart cells.
    The Journal of laboratory and clinical medicine, 1999, Volume: 133, Issue:2

    Topics: Animals; Animals, Newborn; Antioxidants; Ascorbic Acid; Cells, Cultured; Deferiprone; Deferoxamine; Heart; Intracellular Membranes; Iron; Iron Chelating Agents; Mitochondria, Heart; Myocardium; NAD; Pyridones; Rats; Succinate Dehydrogenase; Vitamin E

1999
Biphasic mechanism for hypothermic induced loss of protein synthesis in hepatocytes.
    Transplantation, 1999, Jun-15, Volume: 67, Issue:11

    Topics: Adenosine; Allopurinol; Animals; Antioxidants; Chromans; Cryopreservation; Cytosol; Deferoxamine; Dithiothreitol; Glutathione; Insulin; Leucine; Liver; Organ Preservation Solutions; Protein Biosynthesis; Raffinose; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tritium; Vitamin E

1999
Safrole-induced oxidative damage in the liver of Sprague-Dawley rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1999, Volume: 37, Issue:7

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Alanine Transaminase; Animals; Antidotes; Antioxidants; Aspartate Aminotransferases; Carcinogens; Deferoxamine; Deoxyguanosine; DNA Adducts; DNA Damage; Lipid Peroxides; Liver; Male; Microsomes, Liver; Oxidative Stress; Rats; Rats, Sprague-Dawley; Safrole; Vitamin E

1999
Kupffer cell-independent acute hepatocellular oxidative stress and decreased bile formation in post-cold-ischemic rat liver.
    Hepatology (Baltimore, Md.), 1999, Volume: 30, Issue:6

    Topics: Animals; Antioxidants; Ascorbic Acid; Bile; Clodronic Acid; Cold Temperature; Deferoxamine; Fluoresceins; Hydrogen Peroxide; Kupffer Cells; Liver; Liver Transplantation; Male; Mitochondria, Liver; Oxidative Stress; Rats; Rats, Wistar; Reperfusion Injury; Taurocholic Acid; Vitamin E

1999
Activation of AP-1 and nuclear factor-kappaB transcription factors is involved in hydrogen peroxide-induced apoptotic cell death of oligodendrocytes.
    Journal of neurochemistry, 1999, Volume: 73, Issue:6

    Topics: Animals; Antioxidants; Apoptosis; Aurintricarboxylic Acid; Deferoxamine; DNA Fragmentation; Free Radicals; Gene Expression Regulation; Hydrogen Peroxide; Iron Chelating Agents; Macromolecular Substances; Microscopy, Electron; NF-kappa B; Oligodendroglia; Oxidative Stress; Pyrrolidines; Rats; Rats, Wistar; Reactive Oxygen Species; Thiocarbamates; Transcription Factor AP-1; Transcription, Genetic; Vitamin E

1999
Chromate-induced human erythrocytes haemoglobin oxidation and peroxidation: influence of vitamin E, vitamin C, salicylate, deferoxamine, and N-ethylmaleimide.
    Toxicology letters, 2000, Apr-03, Volume: 114, Issue:1-3

    Topics: Ascorbic Acid; Chromates; Deferoxamine; Erythrocytes; Ethylmaleimide; Hemoglobins; Humans; Oxidation-Reduction; Salicylates; Thiobarbituric Acid Reactive Substances; Time Factors; Vitamin E

2000
Ischemia-reperfusion injury of rabbit kidney: comparative effects of desferrioxamine and N-acetylcysteine as antioxidants.
    Transplantation proceedings, 2000, Volume: 32, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Aspartate Aminotransferases; Deferoxamine; Glutathione; Ischemia; Kidney; Kidney Cortex; L-Lactate Dehydrogenase; Microcirculation; Necrosis; Rabbits; Renal Circulation; Reperfusion Injury; Vitamin E

2000
Molecular basis of vitamin E action. Tocotrienol potently inhibits glutamate-induced pp60(c-Src) kinase activation and death of HT4 neuronal cells.
    The Journal of biological chemistry, 2000, Apr-28, Volume: 275, Issue:17

    Topics: Animals; Benzoquinones; Cell Death; Cells, Cultured; Chelating Agents; Chromans; Chromatography, High Pressure Liquid; Deferoxamine; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; Glutamic Acid; Hippocampus; Immunoblotting; Lactams, Macrocyclic; Mice; Neurons; Phosphotyrosine; Proto-Oncogene Proteins pp60(c-src); Quinones; Rats; Signal Transduction; Time Factors; Tocotrienols; Transfection; Vitamin E

2000
Antioxidants and gadolinium chloride attenuate hepatic parenchymal and endothelial cell injury induced by low flow ischemia and reperfusion in perfused rat livers.
    Free radical research, 2000, Volume: 32, Issue:6

    Topics: Animals; Antioxidants; Blood Flow Velocity; Catalase; Deferoxamine; Endothelium, Vascular; Gadolinium; Ischemia; Kupffer Cells; L-Lactate Dehydrogenase; Liver; Male; Purine-Nucleoside Phosphorylase; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase; Vitamin A; Vitamin E

2000
Glutathione oxidation and PTPase inhibition by hydrogen peroxide in Caco-2 cell monolayer.
    American journal of physiology. Gastrointestinal and liver physiology, 2000, Volume: 279, Issue:2

    Topics: Acetylcysteine; Antineoplastic Agents, Alkylating; Caco-2 Cells; Carmustine; Catalase; Cell Membrane Permeability; Chelating Agents; Deferoxamine; Free Radical Scavengers; Glutathione; Humans; Hydrogen Peroxide; Intestinal Mucosa; Intestines; Iron; Maleates; Oxidants; Oxidation-Reduction; Phenanthrolines; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Signal Transduction; Sulfhydryl Compounds; Superoxide Dismutase; Thiomalates; Tight Junctions; Vitamin A; Vitamin E

2000
Differential cellular regulation of the mitochondrial permeability transition in an in vitro model of 1,3-dinitrobenzene-induced encephalopathy.
    Brain research, 2000, Aug-25, Volume: 874, Issue:2

    Topics: Adenosine Triphosphate; Antioxidants; bcl-2-Associated X Protein; bcl-X Protein; Brain Diseases; Calcium; Deferoxamine; Dinitrobenzenes; Electrophysiology; Glioma; Humans; Mitochondria; Neuroblastoma; Oxidation-Reduction; Permeability; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Trifluoperazine; Tumor Cells, Cultured; Vitamin E

2000
Oxidative insult in sheep red blood cells induced by T-butyl hydroperoxide: the roles of glutathione and glutathione peroxidase.
    Free radical research, 2001, Volume: 34, Issue:1

    Topics: Animals; Antioxidants; Ascorbic Acid; Butylated Hydroxytoluene; Deferoxamine; Dithiothreitol; Erythrocytes; Genetic Engineering; Glutathione; Glutathione Peroxidase; Hemoglobins; Lipid Peroxidation; Membrane Proteins; Oxidative Stress; Sheep; tert-Butylhydroperoxide; Thiobarbituric Acid Reactive Substances; Vitamin E

2001
Individual and synergistic antioxidative actions of melatonin: studies with vitamin E, vitamin C, glutathione and desferrioxamine (desferoxamine) in rat liver homogenates.
    The Journal of pharmacy and pharmacology, 2001, Volume: 53, Issue:10

    Topics: Animals; Antioxidants; Ascorbic Acid; Cell Membrane; Deferoxamine; Dose-Response Relationship, Drug; Drug Synergism; Glutathione; In Vitro Techniques; Lipid Peroxidation; Lipids; Malondialdehyde; Melatonin; Proteins; Rats; Vitamin E

2001
Production of carbon monoxide by cytochrome P450 during iron-dependent lipid peroxidation.
    Toxicology in vitro : an international journal published in association with BIBRA, 2002, Volume: 16, Issue:1

    Topics: alpha-Tocopherol; Animals; Aryl Hydrocarbon Hydroxylases; Carbon Monoxide; Cytochrome P-450 Enzyme System; Deferoxamine; Enzyme Induction; Enzyme Inhibitors; Heme Oxygenase (Decyclizing); In Vitro Techniques; Iron; Lipid Peroxidation; Metyrapone; Microsomes, Liver; Phenobarbital; Proadifen; Protoporphyrins; Rabbits; Steroid Hydroxylases

2002
The effects of desferrioxamin and vitamin E as supplements to antibiotics in the treatment of peritonitis in rats.
    Journal of the Royal College of Surgeons of Edinburgh, 2002, Volume: 47, Issue:5

    Topics: Animals; Clindamycin; Deferoxamine; Drug Therapy, Combination; Gentamicins; Male; Peritonitis; Rats; Rats, Sprague-Dawley; Vitamin E

2002
Protective effects of flavonoids on the cytotoxicity of linoleic acid hydroperoxide toward rat pheochromocytoma PC12 cells.
    Chemico-biological interactions, 2003, Mar-06, Volume: 145, Issue:1

    Topics: alpha-Tocopherol; Animals; Cell Survival; Deferoxamine; Flavonoids; Flow Cytometry; Linoleic Acids; Lipid Peroxides; Microscopy, Fluorescence; PC12 Cells; Rats; Reactive Oxygen Species

2003
The effects of desferrioxamine on cisplatin-induced lipid peroxidation and the activities of antioxidant enzymes in rat kidneys.
    Human & experimental toxicology, 2004, Volume: 23, Issue:1

    Topics: Animals; Antineoplastic Agents; Antioxidants; Ascorbic Acid; Catalase; Cisplatin; Deferoxamine; Female; Glutathione Reductase; Iron Chelating Agents; Kidney; Lipid Peroxidation; Male; Rats; Rats, Wistar; Superoxide Dismutase; Vitamin E

2004
Lipid peroxidation and oxidant stress regulate hepatic apolipoprotein B degradation and VLDL production.
    The Journal of clinical investigation, 2004, Volume: 113, Issue:9

    Topics: Animals; Antioxidants; Apolipoproteins B; Cell Line, Tumor; Cells, Cultured; Chelating Agents; Deferoxamine; Dietary Fats; Docosahexaenoic Acids; Endoplasmic Reticulum; Fatty Acids, Omega-3; Fish Oils; Hepatocytes; Lipid Peroxidation; Lipoproteins, VLDL; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Protein Processing, Post-Translational; Rats; Time Factors; Vitamin E

2004
The role of nitric oxide in iron-induced rat renal injury.
    Human & experimental toxicology, 2004, Volume: 23, Issue:11

    Topics: Animals; Arginine; Deferoxamine; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Iron; Iron Chelating Agents; Iron Overload; Kidney; Kidney Diseases; Kidney Function Tests; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Rats; Rats, Sprague-Dawley; Vitamin E

2004
Effect of alpha-tocopherol and deferoxamine on methamphetamine-induced neurotoxicity.
    Brain research, 2006, Sep-13, Volume: 1109, Issue:1

    Topics: alpha-Tocopherol; Analysis of Variance; Animals; Biogenic Monoamines; Body Temperature; Corpus Striatum; Deferoxamine; Drug Administration Schedule; Drug Interactions; Glutathione; Lipid Peroxidation; Male; Methamphetamine; Motor Activity; Neuroprotective Agents; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; Time Factors

2006
Successful pregnancy outcome following maternal intravenous immunoglobulin treatment in a woman with recurrent perinatal haemochromatosis.
    Prenatal diagnosis, 2006, Volume: 26, Issue:13

    Topics: Acetylcysteine; Adult; Deferoxamine; Diagnosis, Differential; Female; Ferritins; Fetal Diseases; Free Radical Scavengers; Gestational Age; Hemochromatosis; Humans; Hydrops Fetalis; Infant, Newborn; Live Birth; Liver Failure, Acute; Pregnancy; Recurrence; Treatment Outcome; Vitamin E; Vitamin K

2006
Aryl hydrocarbon receptor facilitates DNA strand breaks and 8-oxo-2'-deoxyguanosine formation by the aldo-keto reductase product benzo[a]pyrene-7,8-dione.
    The Journal of biological chemistry, 2009, Oct-23, Volume: 284, Issue:43

    Topics: 8-Hydroxy-2'-Deoxyguanosine; alpha-Tocopherol; Animals; Antioxidants; Basic Helix-Loop-Helix Transcription Factors; Benzopyrenes; Cell Line; Cell Line, Tumor; Deferoxamine; Deoxyguanosine; DNA Breaks; DNA Glycosylases; Humans; Mice; Reactive Oxygen Species; Receptors, Aryl Hydrocarbon; Siderophores

2009
Therapeutic management of neonatal hemochromatosis: report of four cases and literature review.
    Human & experimental toxicology, 2011, Volume: 30, Issue:10

    Topics: Acetylcysteine; Antioxidants; Deferoxamine; Female; Hemochromatosis; Humans; Infant, Newborn; Selenium; Siderophores; Vitamin E

2011
Oxidation of low-density lipoprotein by iron at lysosomal pH: implications for atherosclerosis.
    Biochemistry, 2012, May-08, Volume: 51, Issue:18

    Topics: alpha-Tocopherol; Atherosclerosis; Chlorides; Deferoxamine; Ferric Compounds; Ferrous Compounds; Hydrogen-Ion Concentration; Iron Chelating Agents; Lipoproteins, LDL; Lysosomes; Pentetic Acid

2012
JNK activation is required for TNFα-induced apoptosis in human hepatocarcinoma cells.
    International immunopharmacology, 2013, Volume: 17, Issue:1

    Topics: Anthracenes; Antioxidants; Apoptosis; Butylated Hydroxyanisole; Carcinoma, Hepatocellular; Caspases; Cell Line, Tumor; Chelating Agents; Cycloheximide; Deferoxamine; Humans; JNK Mitogen-Activated Protein Kinases; Liver Neoplasms; RNA Interference; RNA, Small Interfering; Signal Transduction; Tumor Necrosis Factor-alpha; Vitamin E

2013
Deferoxamine promotes osteoblastic differentiation in human periodontal ligament cells via the nuclear factor erythroid 2-related factor-mediated antioxidant signaling pathway.
    Journal of periodontal research, 2014, Volume: 49, Issue:5

    Topics: Acetylcysteine; Antioxidant Response Elements; Buthionine Sulfoximine; Calcification, Physiologic; Calcium; Cell Differentiation; Cell Line; Deferoxamine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Glutamate-Cysteine Ligase; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Humans; Maleates; MAP Kinase Signaling System; NF-E2-Related Factor 2; NF-kappa B; Osteoblasts; Periodontal Ligament; Reactive Oxygen Species; RNA, Small Interfering; Siderophores; Signal Transduction; Vitamin E

2014
Involvement of reactive oxygen species in brominated diphenyl ether-47-induced inflammatory cytokine release from human extravillous trophoblasts in vitro.
    Toxicology and applied pharmacology, 2014, Jan-15, Volume: 274, Issue:2

    Topics: alpha-Tocopherol; Antioxidants; Cell Line; Cell Survival; Cyclic N-Oxides; Cytokines; Deferoxamine; Female; Halogenated Diphenyl Ethers; Humans; Inflammation; Interleukin-6; Interleukin-8; Membrane Potential, Mitochondrial; Milk, Human; Placenta; Pregnancy; Pregnancy Trimester, First; Reactive Oxygen Species; RNA, Messenger; Spin Labels; Trophoblasts

2014
Deferoxamine prevents cerebral glutathione and vitamin E depletions in asphyxiated neonatal rats: role of body temperature.
    International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 2016, Volume: 32, Issue:2

    Topics: Animals; Animals, Newborn; Body Temperature; Brain; Deferoxamine; Female; Glutathione; Hyperthermia, Induced; Hypoxia; Male; Malondialdehyde; Rats; Rats, Wistar; Vitamin E

2016
Ferroptosis driven by radical oxidation of n-6 polyunsaturated fatty acids mediates acetaminophen-induced acute liver failure.
    Cell death & disease, 2020, 02-24, Volume: 11, Issue:2

    Topics: Acetaminophen; alpha-Tocopherol; Animals; Antioxidants; Coenzyme A Ligases; Cyclohexylamines; Cyclooxygenase 2; Deferoxamine; Disease Models, Animal; Fatty Acids, Omega-6; Ferroptosis; Hepatocytes; Humans; Iron Chelating Agents; Lipid Peroxidation; Liver; Liver Failure, Acute; Mice, Inbred C57BL; Mice, Knockout; Oxidation-Reduction; Phenylenediamines

2020
Iron-overloaded follicular fluid increases the risk of endometriosis-related infertility by triggering granulosa cell ferroptosis and oocyte dysmaturity.
    Cell death & disease, 2022, 07-04, Volume: 13, Issue:7

    Topics: Animals; Deferoxamine; Endometriosis; Female; Ferroptosis; Follicular Fluid; Granulosa Cells; Humans; Infertility, Female; Iron; Iron Overload; Mice; Oocytes; Vitamin E

2022