Compounds > deferoxamine

deferoxamine and cyclosporine

deferoxamine has been researched along with cyclosporine in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's1 (8.33)18.2507
2000's4 (33.33)29.6817
2010's5 (41.67)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
D'Acunto, CW; Gonzalez, G; Hodoň, J; Kaňovský, P; Kazakova, A; Strnad, M; Urban, M1
Atlef, N; Doll, N; Hermitte, L; Payan, MJ; Scheimann, A; Vague, P; Vialettes, B1
Armstrong, JM; Buetler, TM; Cottet-Maire, F; Krauskopf, AS; Lo Russo, A; Macé, K; Nguyen, NS; Rüegg, UT; Vickers, AE1
Ding, WX; Ong, CN; Shen, HM1
Castranova, V; Costa, M; Huang, C; Ju, G; Leonard, SS; Li, J; Shi, X; Vallyathan, V; Zhang, Z1
Huang, H; Jenkins, JK; Joshi, M; Moore, NA; Salahudeen, AK1
Chakrabarti, SK; Lemieux, N; M'Bemba-Meka, P1
Amiot, BP; Glorioso, J; Liu, H; Mao, S; Nyberg, SL; Rinaldo, P; Rodysil, B; Yu, Y1

Reviews

1 review(s) available for deferoxamine and cyclosporine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

11 other study(ies) available for deferoxamine and cyclosporine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Novel pentacyclic triterpenes exhibiting strong neuroprotective activity in SH-SY5Y cells in salsolinol- and glutamate-induced neurodegeneration models.
    European journal of medicinal chemistry, 2021, Mar-05, Volume: 213

    Topics: Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Glutamic Acid; Humans; Isoquinolines; Membrane Potential, Mitochondrial; Models, Biological; Molecular Structure; Neuroprotective Agents; Oxidative Stress; Structure-Activity Relationship; Triazoles; Triterpenes

2021
High dose nicotinamide fails to prevent diabetes in BB rats.
    Autoimmunity, 1989, Volume: 5, Issue:1-2

    Topics: Age Factors; Animals; Autoimmune Diseases; Blood Glucose; Cyclosporine; Deferoxamine; Diabetes Mellitus, Experimental; DNA Damage; Drug Evaluation, Preclinical; Hyperplasia; Insulin; Insulin Secretion; Islets of Langerhans; Models, Biological; NAD; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Rats, Inbred BB

1989
Metabolism-dependent stimulation of reactive oxygen species and DNA synthesis by cyclosporin A in rat smooth muscle cells.
    Free radical biology & medicine, 1999, Volume: 27, Issue:11-12

    Topics: Animals; Aorta; Aryl Hydrocarbon Hydroxylases; Chelating Agents; Chromatography, High Pressure Liquid; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Deferoxamine; Ditiocarb; DNA; Enzyme Inhibitors; Fluorescent Dyes; Male; Muscle, Smooth, Vascular; Oxidation-Reduction; Oxidoreductases, N-Demethylating; Protein Kinase C; Rats; Rats, Inbred WKY; Reactive Oxygen Species; RNA, Messenger

1999
Critical role of reactive oxygen species and mitochondrial permeability transition in microcystin-induced rapid apoptosis in rat hepatocytes.
    Hepatology (Baltimore, Md.), 2000, Volume: 32, Issue:3

    Topics: Animals; Apoptosis; Cell Polarity; Cell Survival; Chelating Agents; Cyclosporine; Deferoxamine; Intracellular Membranes; L-Lactate Dehydrogenase; Liver; Male; Marine Toxins; Microcystins; Mitochondria; Peptides, Cyclic; Permeability; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Time Factors

2000
Hydrogen peroxide mediates activation of nuclear factor of activated T cells (NFAT) by nickel subsulfide.
    Cancer research, 2001, Nov-15, Volume: 61, Issue:22

    Topics: Acetylcysteine; Animals; Calcineurin; Calcium; Carcinogens; Cells, Cultured; Chelating Agents; Cyclosporine; Deferoxamine; DNA-Binding Proteins; Drug Synergism; Fibroblasts; Free Radical Scavengers; Hydrogen Peroxide; Mice; NFATC Transcription Factors; Nickel; Nuclear Proteins; Reactive Oxygen Species; Thapsigargin; Transcription Factors; Transcriptional Activation; Transfection

2001
Involvement of the mitochondrial pathway in cold storage and rewarming-associated apoptosis of human renal proximal tubular cells.
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2003, Volume: 3, Issue:3

    Topics: Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspases; Cells, Cultured; Chromans; Cold Temperature; Cyclosporine; Cytochromes c; Cytosol; Deferoxamine; Enzyme Activation; Free Radical Scavengers; Humans; In Situ Nick-End Labeling; Kidney Tubules, Proximal; Microscopy, Electron; Mitochondria; Piperazines; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Specimen Handling; Temperature; Time Factors; Tissue Preservation

2003
Role of oxidative stress, mitochondrial membrane potential, and calcium homeostasis in nickel sulfate-induced human lymphocyte death in vitro.
    Chemico-biological interactions, 2005, Sep-10, Volume: 156, Issue:1

    Topics: Acetylcysteine; Calcium; Catalase; Cell Death; Cyclosporine; Deferoxamine; Glutathione; Homeostasis; Humans; Hydrogen Peroxide; Lymphocytes; Mannitol; Membrane Potentials; Mitochondria; Nickel; Oxidative Stress; Thiourea

2005
Cold storage of rat hepatocyte spheroids.
    Cell transplantation, 2014, Volume: 23, Issue:7

    Topics: Adenosine; Albumins; Allopurinol; Ammonia; Animals; Cell Survival; Cold Temperature; Culture Media, Serum-Free; Cyclosporine; Cytochrome P-450 Enzyme System; Deferoxamine; Glutathione; Hepatocytes; Insulin; Organ Preservation Solutions; Raffinose; Rats; Spheroids, Cellular; Time Factors; Urea

2014