deferoxamine has been researched along with ascorbic acid in 224 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 86 (38.39) | 18.7374 |
| 1990's | 75 (33.48) | 18.2507 |
| 2000's | 35 (15.63) | 29.6817 |
| 2010's | 25 (11.16) | 24.3611 |
| 2020's | 3 (1.34) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Flynn, DM; Green, N; Hoffbrand, AV; Hussain, MA | 1 |
| Callender, ST; Pippard, MJ; Warner, GT; Weatherall, DJ | 1 |
| García-Ibañez, R; Torún, B; Viteri, FE | 1 |
| Dybing, E | 1 |
| Graziano, JH | 1 |
| Gordon, FS; Hanan, ZI; Levine, HG; Tomasulo, WJ | 1 |
| Cohen, A; Schwartz, E | 4 |
| Bender-Götze, C | 1 |
| Bunn, HF; Cooper, B; Moloney, WC; Nathan, DG; Propper, RD; Rosenthal, DS | 2 |
| Callender, ST; Pippard, MJ; Weatherall, DJ | 1 |
| Hart, D; Henry, WL; Karpatkin, M; Piomelli, S; Seaman, C; Vora, SK; Weiner, M | 1 |
| Beutler, E; Blume, KG; Chillar, RK; Fahey, JL; Sharkoff, D; Zia, PK | 1 |
| Barbui, T; Battista, R; Cartei, G; Cazzavillan, M; Chisesi, T; Dini, E | 2 |
| Fairbanks, VF | 1 |
| Aamodt, R; Anderson, WF; Bartter, F; Delea, C; Nienhuis, AW | 1 |
| Nienhuis, AW | 2 |
| Modell, B | 1 |
| Anderson, WF; Bunn, HF; Cooper, B; Nathan, DG; Nienhuis, AW; Propper, RD; Rosenthal, A; Rufo, RR | 1 |
| Layrisse, M; Leets, I; Martínez-Torres, C | 1 |
| Carmichael, AJ; Gray, B | 1 |
| Ferrari, M; Forte, T; Menditto, A; Minetti, M; Quaresima, V; Soriani, M | 1 |
| Beach, DC; Giroux, E | 1 |
| Kim, H; Kirschenbaum, LJ; Riesz, P; Rosenthal, I | 1 |
| Fukazawa, K; Murakami, K; Muto, N; Yamamoto, I | 1 |
| Christen, Y; Clostre, F; Costentin, J; Naudin, B; Ramassamy, C | 1 |
| Green, JW; Hulgan, TM; Jenkins, LD; Moore, RB | 1 |
| Bhuyan, DK; Bhuyan, KC; Chiu, W; Fridovich, I; Malik, S | 1 |
| Hebbel, RP; Repka, T | 1 |
| Aruoma, OI; Cecchini, R; Halliwell, B | 1 |
| Corbella, J; Domingo, JL; Gómez, M; Llobet, JM | 1 |
| Frimodt-Møller, N; Hartzen, SH; Thomsen, VF | 2 |
| Brunk, UT; Zdolsek, JM; Zhang, H | 1 |
| Aitken, RJ; Johnson, MH; Nasr-Esfahani, M | 1 |
| Martorana, GE; Meucci, E; Miggiano, GA; Mordente, A | 1 |
| Buettner, GR; Chamulitrat, W | 1 |
| Henderson, JS; Singh, A; Singh, H | 1 |
| Farber, JL; Kyle, ME; Sakaida, I | 1 |
| Blount, S; Griffiths, HR; Lunec, J | 1 |
| Beyer, WF; Fridovich, I | 1 |
| Hamazaki, S; Li, JL; Midorikawa, O; Okada, S; Toyokuni, S | 1 |
| Jonas, SK; Riley, PA; Willson, RL | 1 |
| Baysal, E; Stern, A; Sullivan, SG | 1 |
| Frimodt-Møller, N; Frølund Thomsen, V; Hartzen, SH | 1 |
| Baysal, E; Jones, JG; Jones, SA; Rice-Evans, C; Singh, S | 1 |
| Khan, R; Okunade, G; Rice-Evans, C | 1 |
| Eaton, JW; Sadrzadeh, SM | 1 |
| Buettner, GR | 1 |
| Hershko, C; Weatherall, DJ | 1 |
| Pippard, MJ | 1 |
| Aldouri, MA; Barr, J; Hoffbrand, AV; Kontoghiorghes, GJ; Kourouclaris, T; Sheppard, L; Wonke, B | 1 |
| Dandona, P; Hoffbrand, AV; Jeremy, JY; Kontoghiorghes, GJ | 1 |
| Bhattacharya, DK; Chandra, S; Dutta, AK; Ray, R | 1 |
| Domingo, JL; Gómez, M; Llobet, JM; Paternain, JL | 1 |
| Henderson, JS; Migliore, RD; Rousseau, J; Singh, A; Singh, H; Van Lier, JE | 1 |
| Areekul, S; Hathirat, P; Isarangkura, P; Pleehachinda, R; Tuntawiroon, M | 1 |
| Bridges, KR; Hoffman, KE | 1 |
| Baysal, E; Rice-Evans, C | 1 |
| Hoffman, K; Jackson, MJ; Modell, CB; Petrou, M; Pippard, MJ | 1 |
| Baysal, E; Omorphos, SC; Rice-Evans, C | 1 |
| Baysal, E; Flynn, DM; Hoffbrand, AV; Kontoghiorghes, GJ; Rice-Evans, C | 1 |
| Festa, RS | 1 |
| Huehns, ER; Marcus, RE | 1 |
| MacDonald, RA; MacSween, RN; Pechet, GS | 1 |
| Björn-Rasmussen, E | 1 |
| Wills, ED | 1 |
| Cerami, A; Grady, RW; Graziano, JH | 1 |
| O'Brien, RT | 1 |
| Beck, J; Modell, CB | 1 |
| Popplewell, DS | 1 |
| Oski, FA; Stockman, JA | 1 |
| Greenman, DA; Tennant, GB | 1 |
| Morgan, EH | 1 |
| Saito, H | 1 |
| Bothwell, TH; Charlton, RW; Lynch, SR; Seftel, HC; Wapnick, AA | 1 |
| Dymock, IW; Godfrey, BE; Miller, JP; Williams, R | 1 |
| Cartei, G; Meani, A | 1 |
| Moerkerk, C; Schretlen, ED; Trijbels, JM; van Munster, PJ; Werkman, HP | 1 |
| Layrisse, M; Martínez-Torres, C | 1 |
| Kuhn, IN; Layrisse, M; Martinez, C; Roche, M; Walker, RB | 1 |
| Roeser, HP | 1 |
| Marcelis, JH; Marx, JJ; Struyvenberg, A; van Asbeck, BS; van Kats, JH; Verhoef, J | 1 |
| Dervan, PB; Hertzberg, RP | 1 |
| Bianchi, PA; Brunelli, L; Conte, D; Ferrario, L; Mandelli, C; Quatrini, M; Velio, P | 1 |
| Van der Weyden, MB | 1 |
| Buonanno, G; Cantore, N; Gonnella, F; Tortarolo, M; Valente, A; Volpe, E | 1 |
| Murray, JA | 1 |
| Halliwell, B | 1 |
| Blake, D; Gutteridge, JM; Halliwell, B; Harrison, PM; Treffry, A | 1 |
| Callender, ST; Pippard, MJ | 1 |
| Anderson, WF; Borer, J; Griffith, P; Henry, W; Leon, M; Nienhuis, AW; Strawczynski, H | 1 |
| Dudell, GG; Graziano, J; Hart, D; Hilgartner, M; Karpatkin, M; Khanna, K; Piomelli, S; Valdes-Cruz, LM; Vora, S | 1 |
| Frank, M; Siller, V | 1 |
| Griffith, P; Ley, TJ; Nienhuis, AW | 1 |
| Callender, ST; Finch, CA; Pippard, MJ | 1 |
| Ambruso, DR; Githens, JH; Mahony, BS; Rhoades, ED | 1 |
| Odumosu, A | 1 |
| Choi, YC; Hough, AJ; Morris, GM; Sokoloff, L | 1 |
| Brock, JH; Esparza, I | 1 |
| Anderson, D; Phillips, BJ; Schmezer, P; Yu, TW | 1 |
| Dzwigaj, S; Pezerat, H | 1 |
| Furuno, K; Suetsugu, T; Sugihara, N | 1 |
| Farber, JL; Gilfor, E; Glascott, PA | 1 |
| Günther, T; Höllriegl, V; Vormann, J | 1 |
| Altman, SA; Dizdaroglu, M; Lumpkin, JA; Madurawe, R; Randers-Eichhorn, L; Rao, G; Zastawny, TH | 1 |
| Fuchinoue, S; Ota, K; Ozaki, M; Teraoka, S | 1 |
| Boura, P; Karolides, A; Kountouras, J; Tsapas, G; Zaharioudaki, E | 1 |
| Beale, SI; Rhie, G | 1 |
| Lightbody, JH; McMaster, D; Tate, S; Trimble, ER; Young, IS | 1 |
| Brunner, M; Moeslinger, T; Spieckermann, PG | 1 |
| Ali, BH; Bashir, AA; Ben Ismail, TH | 1 |
| Herbert, V; Jayatilleke, E; Shaw, S; Stopler-Kasdan, T | 1 |
| Gantchev, T; Kagan, V; Stoyanovsky, D; Yalowich, J | 1 |
| Inoue, F; Kaneko, M; Kodama, M | 1 |
| Sagripanti, JL; Toyokuni, S | 1 |
| Fernandez, Y; Mitjavila, MT; Mitjavila, S; Muntané, J; Puig-Parellada, P | 1 |
| Azorin, I; Bella, MC; Fornas, E; Iborra, FJ; Renau-Piqueras, J | 1 |
| Gajdusek, C; Harada, T; London, S; Luo, Z; Mayberg, MR | 1 |
| Courtiere, A; Molard, F; Reybaud, J | 1 |
| Dean, RT; Van Reyk, DM | 1 |
| Andorn, AC; Bacon, BR; Britton, RS | 1 |
| Blake, DR; Dai, L; Morris, CJ; Winyard, PG; Zhang, Z | 1 |
| Crkovská, J; Pláteník, J; Stastný, F; Stípek, S; Zima, T | 1 |
| Anthonypillai, V; Bach, PH; Brant, S; Kaler, B; Obatomi, DK | 1 |
| Lai, CT; Yu, PH | 1 |
| Des Rosiers, C; Montgomery, J; St-Germain, F; Vachon, B | 1 |
| Cederbaum, AI; Chen, Q; Galleano, M | 1 |
| Aguirre, DE; Fink, MP; Menconi, MJ; Smith, M; Unno, N | 1 |
| Furukawa, Y; Sugiyama, M; Susa, N; Ueno, S | 1 |
| Fleisher, LN; Goralska, M; Grimes, AM; Harned, J; McGahan, MC | 1 |
| Fukuchi, K; Gomi, K; Sakagami, H; Satoh, K; Takeda, M | 1 |
| Huang, XQ; McAnulty, JF | 1 |
| Hubel, CA; Kagan, VE; Kisin, ER; McLaughlin, MK; Roberts, JM | 1 |
| Grabowska-Maślanka, H; Janik, A | 2 |
| Bagger, JP; Christensen, T; Ellegaard, J; Jensen, FT; Jensen, PD; Olsen, N | 1 |
| Higuchi, Y; Matsukawa, S | 1 |
| Dayan, FE; Duke, SO; Faibis, V; Jacobs, JM; Jacobs, NJ | 1 |
| Jang, YJ; Kang, SA; Park, H | 1 |
| Chiueh, CC; Khaldi, A; Mohanakumar, KP; Rauhala, P | 1 |
| Dailly, E; Tillement, JP; Urien, S | 1 |
| Bekerecioğlu, M; Ozyazgan, I; Tercan, M | 1 |
| Jung, CH; Wells, WW | 1 |
| Collell, M; Dresow, B; Dürken, M; Engelhardt, R; Fischer, R; Nielsen, P; Piga, A; Politis, C; Reller, K | 1 |
| Benderitter, M; Briot, F; Dalloz, F; Maupoil, V; Rochette, L; Vergely, C | 1 |
| Baggott, JE; Cornwell, PE; Eto, I; Johanning, GL; Robinson, CB | 1 |
| Gal-Or, S; Jonas, A; Katzir, E; Neeman, I; Nimni, ME; Perelman, N; Rosenblat, G; Sorgente, N | 1 |
| Klebanov, GI; Lyubitsky, OB; Vasiljeva, OV | 1 |
| Chain, BM; Foreman, JC; Tatla, S; Woodhead, V | 1 |
| Hershko, C; Konijn, AM; Link, G | 1 |
| Baan, J; Dorrepaal, CA; Moison, R; Shadid, M; Steendijk, P; Van Bel, F; Van Der Velde, ET | 1 |
| Bergamini, S; Iannone, A; Rota, C; Staffieri, M; Tomasi, A | 1 |
| Herbert, V | 1 |
| Ball, JG; Harmon, RC; Hong, SK; Meadows, MK; Rankin, GO; Valentovic, M | 1 |
| Hirano, KI; Ishimura, Y; Kato, Y; Kitajima, M; Kumamoto, Y; Makino, N; Naito, M; Sano, T; Shimazu, M; Suematsu, M; Wakabayashi, G | 1 |
| Alpoim, MC; Fernandes, MA; Geraldes, CF; Oliveira, CR | 1 |
| Borisenko, GG; Hsia, CJ; Kagan, VE; Schor, NF | 1 |
| Fakata, KL; Sommer, D; Stemmer, PM; Swanson, SA | 1 |
| Diamond, E; Drigues, N; Klein, I; Lischinsky, S; Nagler, R; Reznick, AZ | 1 |
| Delogu, MR; Desole, MS; Esposito, G; Grella, G; Miele, E; Miele, M; Migheli, R; Rocchitta, G; Serra, PA | 1 |
| Bandy, B; Davison, AJ; Li, AS; Tsang, SS | 1 |
| Buettner, GR; Lange, BA | 1 |
| Agar, NS; Jone, GL; Zou, CG | 1 |
| Beschmann, HA; Brömme, HJ; Fuchs, J; Goy, C; Mörke, W; Ochsendorf, FR | 1 |
| Gaskell, SJ; Gielbert, J; Hebestreit, HF; Jaakkola, P; Maxwell, PH; Mole, DR; Mukherji, M; Pugh, CW; Ratcliffe, PJ; Schofield, CJ; Tian, YM; von Kriegsheim, A; Wilson, MI | 1 |
| Ball, JG; Rankin, GO; Stoll, S; Valentovic, M | 1 |
| Beren, J; Diener-West, M; Hill, SL; Rose, NR | 1 |
| Arkan, MC; Başağa, H; Biasi, F; Leonarduzzi, G; Poli, G | 1 |
| Delogu, MR; Desole, MS; Esposito, G; Miele, E; Miele, M; Migheli, R; Rocchitta, G; Serra, PA | 1 |
| Barberi, I; Cuzzocrea, S; Fulia, F; Gitto, E; Karbownik, M; Manchester, LC; Reiter, RJ; Tan, DX | 1 |
| Dunster, C; Grieve, DJ; Kelly, FJ; Li, JM; MacCarthy, PA; Shah, AM | 1 |
| Bechtold, M; Frahry, G; Liszkay, A; Schopfer, P; Wagner, A | 1 |
| Chang, MC; Hahn, LJ; Ho, YS; Jeng, JH; Kok, SH; Lee, JJ | 1 |
| Che, CT; Ip, SP; Sun, HD; Yang, H | 1 |
| Chaston, TB; Lovejoy, DB; Richardson, DR; Watts, RN | 1 |
| Crissman, KM; Ghio, AJ; Piantadosi, CA; Richards, JH; Roggli, VL; Stonehuerner, JD | 1 |
| Akalin, N; Balkaya, M; Bolaman, Z; Demir, S; Enli, Y; Kadikoylu, G | 1 |
| Cui, JG; Kruck, TP; Lukiw, WJ; Percy, ME | 1 |
| Juang, HH | 1 |
| Iida, M; Iino, K; Iwase, M; Sonoki, K; Yoshinari, M | 1 |
| Crumbliss, AL; Mies, KA; Wirgau, JI | 1 |
| El Kelany, RS; Emara, AM; Moustafa, KA | 1 |
| Burke, JM; Rozanowska, MB; Sarna, TJ; Zadlo, A | 1 |
| Akatov, VS; Soloviev, VV; Solovieva, ME | 1 |
| Castruita, M; Elmegreen, LA; Morel, FM; Shaked, Y; Stiefel, EI | 1 |
| Alberti, D; Coates, T; Evans, P; Giardina, PJ; Harmatz, P; Holland, J; Kwiatkowski, JL; Macklin, EA; Neufeld, EJ; Olivieri, N; Porter, J; Vichinsky, E; Walter, PB | 1 |
| Clarke, SE; Hollis, FJ; Maggs, JL; Naisbitt, DJ; Park, BK; Sanderson, JP | 1 |
| Alvarez, LD; Clarêncio, J; Costa, MF; Costa, SL; El-Bachá, RS; Lima, RM | 1 |
| Chung, KT; Makena, PS; Pierce, SC; Sinclair, SE | 1 |
| Claro, LM; Comar, SR; do Nascimento, AJ; Krukoski, DW; Leonart, MS | 1 |
| Fariss, MW; Joyce, AR; McKallip, RJ; Mitchell, C; Piper, JT | 1 |
| May, JM; Qu, ZC | 1 |
| Boehm, ME; Haaf, E; Lehmann, WD; Schlosser, A; Seidler, J; Winter, D; Zinn, N | 1 |
| Bowen, L; Doran, SF; Fernandez, S; Jurkuvenaite, A; Matalon, S; Postlethwait, EM; Squadrito, GL; Yadav, AK; Zarogiannis, SG | 1 |
| Aidasani, D; Reid, DL; Skiles, GL; Subramanian, R; Tam, J | 1 |
| Frikke-Schmidt, H; Loft, S; Lykkesfeldt, J; Møller, P; Nøjgaard, JK; Roursgaard, M | 1 |
| Caruana, M; Giese, A; Hillmer, A; Högen, T; Levin, J; Vassallo, N | 1 |
| Choi, KC; Kook, SH; Lee, JC; Lee, SA; Son, YO | 1 |
| Basha, MT; Bernhardt, PV; Gutierrez, E; Jansson, PJ; Kalinowski, DS; Lovejoy, DB; Quach, P; Richardson, DR; Sharpe, PC | 1 |
| Bendová, P; Hašková, P; Hrušková, K; Jansová, H; Kovaříková, P; Macková, E; Simůnek, T; Vávrová, A; Vávrová, K | 1 |
| Benoit-Vical, F; Berry, A; Gales, A; Huyghe, E; Njomnang Soh, P; Pipy, B; Witkowski, B | 1 |
| Gumiri, S; Hosokawa, T; Kihara, Y; Kurasaki, M; Saito, T; Tanaka, M; Tanaka, S | 1 |
| Bader, B; Bötzel, K; Giese, A; Hillmer, AS; Högen, T; Kamp, F; Kretzschmar, HA; Levin, J; Schmidt, F | 1 |
| Qiao, C; Wang, L; Xiao, SH; Xue, J | 1 |
| Di Lorenzo, B; Di Lorenzo, F | 1 |
| Ibrahim, MA; Isah, MB | 1 |
| Hoffman, JD; Loo, G; Ward, WM | 1 |
| Giammar, DE; Kraemer, SM; Schenkeveld, WD; Wang, Z | 1 |
| Belting, M; Bourseau-Guilmain, E; Cheng, F; Fransson, LÅ; Mani, K | 1 |
| Hori, M; Ito, F; Mizuno, M; Okazaki, Y; Richardson, DR; Shi, L; Tanaka, H; Toyokuni, S; Wang, Y | 1 |
| Codd, R; Double, KL; Finkelstein, DI; Gotsbacher, MP; Telfer, TJ; Witting, PK | 1 |
| Allen, BG; Berg, DJ; Brandt, KE; Buettner, GR; Cullen, JJ; Falls, KC; Fath, MA; Gu, Z; Rodman, SN; Schoenfeld, JD; Spitz, DR; Wagner, BA; Zhan, F | 1 |
| Chen, L; He, N; Huang, Y; Kang, Q; Shen, D; Wang, X; Wang, Y | 1 |
| Espósito, BP; Kaneko, TM; Lombardo, M; Lourenço, FR | 1 |
| Aguayo, R; Gajardo, A; Lillo-Moya, J; Panieri, E; Prieto, JC; Puentes, Á; Ramos, C; Rodrigo, R; Rojas-Solé, C; Saso, L | 1 |
| Dong, Y; Du, GF; Fan, X; Le, YJ; Yang, XY; Yin, A | 1 |
13 review(s) available for deferoxamine and ascorbic acid
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Iron metabolism and chelation therapy in hemosiderosis.
Topics: Ascorbic Acid; Blood Transfusion; Chelating Agents; Deferoxamine; Diet; Gentisates; Hemochromatosis; Hemosiderosis; Hydroxamic Acids; Hydroxybenzoates; Iron; Piperazines; Syndrome | 1978 |
Evaluation of desferrioxamine and ascorbic acid for the treatment of chronic iron overload.
Topics: Adolescent; Adult; Aged; Anemia; Ascorbic Acid; Deferoxamine; Drug Evaluation; Feces; Humans; Iron; Leukocytes; Thalassemia | 1976 |
Iron-chelating therapy.
Topics: Animals; Ascorbic Acid; Deferoxamine; Hemochromatosis; Humans; Iron; Iron Chelating Agents | 1988 |
Iron overload and iron chelation therapy in thalassaemia and sickle cell haemoglobinopathies.
Topics: Anemia, Sickle Cell; Ascorbic Acid; Deferoxamine; Drug Administration Schedule; Forecasting; Humans; Iron; Iron Chelating Agents; Sickle Cell Trait; Thalassemia | 1987 |
Modern management of thalassemia.
Topics: Adolescent; Arrhythmias, Cardiac; Ascorbic Acid; Blood Transfusion; Child; Cholelithiasis; Deferoxamine; Endocrine System Diseases; Female; Folic Acid; Growth Disorders; Heart Failure; Hematopoiesis; Humans; Iron; Leg Ulcer; Liver Diseases; Male; Pericarditis; Splenectomy; Thalassemia; Vitamin E | 1985 |
Transfusional iron overload.
Topics: Ascorbic Acid; Blood Transfusion; Deferoxamine; Endocrine Glands; Heart; Humans; Infusions, Parenteral; Iron; Iron Chelating Agents; Liver; Stroke Volume; Thalassemia | 1985 |
The role of ascorbic acid in the turnover of storage iron.
Topics: Adult; Animals; Ascorbic Acid; Deferoxamine; Ferritins; Guinea Pigs; Haplorhini; Hemochromatosis; Hemosiderin; Humans; Iron; Iron Chelating Agents; Liver; Male; Rats; Scurvy; Spleen; Thalassemia | 1983 |
[Recommendations for therapy of juvenile thalassemia major].
Topics: Ascorbic Acid; Blood Transfusion; Child; Deferoxamine; Female; Germany, West; Greece; Hemosiderosis; Humans; Male; Thalassemia; Trace Elements; Turkey | 1980 |
Transfusion haemosiderosis and chelation therapy.
Topics: Adolescent; Adult; Ascorbic Acid; Blood Transfusion; Cardiomyopathies; Deferoxamine; Dose-Response Relationship, Drug; Ferritins; Growth Disorders; Heart Diseases; Hemosiderosis; Humans; Iron; Iron Chelating Agents; Liver; Liver Diseases; Pancreatic Diseases; Parathyroid Diseases; Pituitary Diseases; Thyroid Function Tests | 1982 |
Most free-radical injury is iron-related: it is promoted by iron, hemin, holoferritin and vitamin C, and inhibited by desferoxamine and apoferritin.
Topics: Animals; Anticarcinogenic Agents; Apoferritins; Ascorbic Acid; Carcinogens; Deferoxamine; Diet; Ferritins; Free Radicals; Heart Diseases; Hemin; Humans; Iron; Neoplasms; Oxidation-Reduction; Superoxides | 1994 |
The role of antioxidants treatment on the pathogenesis of malarial infections: a review.
Topics: Acetylcysteine; Antimalarials; Antioxidants; Ascorbic Acid; Deferoxamine; Folic Acid; Humans; Malaria; Oxidative Stress; Plasmodium; Vitamin E | 2014 |
Joint Cardioprotective Effect of Vitamin C and Other Antioxidants against Reperfusion Injury in Patients with Acute Myocardial Infarction Undergoing Percutaneous Coronary Intervention.
Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Biomarkers; Deferoxamine; Dose-Response Relationship, Drug; Drug Synergism; Female; Humans; Male; Myocardial Infarction; Oxidative Stress; Percutaneous Coronary Intervention; Polyphenols; Protective Agents; Reactive Oxygen Species; Reperfusion Injury; Signal Transduction; Stroke Volume; Tocopherols; Ventricular Function, Left | 2021 |
3 trial(s) available for deferoxamine and ascorbic acid
| Article | Year |
|---|---|
Effective chelation of iron in beta thalassaemia with the oral chelator 1,2-dimethyl-3-hydroxypyrid-4-one.
Topics: Administration, Oral; Adolescent; Adult; Aged; Ascorbic Acid; Clinical Trials as Topic; Deferiprone; Deferoxamine; Drug Therapy, Combination; Female; Humans; Iron; Iron Chelating Agents; Male; Middle Aged; Neural Tube Defects; Pyridones; Thalassemia | 1987 |
Recombinant a2 interferon (a-IFN) with chemo-hormonal therapy in patients with hepatocellular carcinoma (HCC).
Topics: Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Carcinoma, Hepatocellular; Combined Modality Therapy; Deferoxamine; Doxorubicin; Drug Administration Schedule; Female; Humans; Interferon alpha-2; Interferon-alpha; Liver Neoplasms; Male; Middle Aged; Recombinant Proteins; Survival Rate; Tamoxifen | 1995 |
Inflammation and oxidant-stress in beta-thalassemia patients treated with iron chelators deferasirox (ICL670) or deferoxamine: an ancillary study of the Novartis CICL670A0107 trial.
Topics: Adolescent; Adult; Ascorbic Acid; Benzoates; beta-Thalassemia; C-Reactive Protein; Child; Deferasirox; Deferoxamine; Female; Humans; Iron Chelating Agents; Lipid Peroxidation; Male; Oxidants; Oxidative Stress; Triazoles; Vitamin E | 2008 |
208 other study(ies) available for deferoxamine and ascorbic acid
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Effect of dose, time, and ascorbate on iron excretion after subcutaneous desferrioxamine.
Topics: Administration, Oral; Adolescent; Adult; Anemia, Sideroblastic; Ascorbic Acid; Child; Deferoxamine; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Female; Hemosiderosis; Humans; Infusions, Parenteral; Iron; Male; Skin; Thalassemia; Transfusion Reaction | 1977 |
Iron absorption in iron-loading anaemias: Effect of subcutaneous desferrioxamine infusions.
Topics: Administration, Oral; Adolescent; Adult; Anemia, Aplastic; Anemia, Sideroblastic; Ascorbic Acid; Binding Sites; Blood Transfusion; Deferoxamine; Drug Synergism; Erythrocytes; Female; Ferritins; Ferrous Compounds; Humans; Infusions, Parenteral; Intestinal Absorption; Iron; Iron Radioisotopes; Isotope Labeling; Male; Thalassemia | 1977 |
Sodium iron NaFeEDTA as an iron fortification compound in Central America. Absorption studies.
Topics: Absorption; Adult; Aging; Ascorbic Acid; Central America; Child, Preschool; Deferoxamine; Edetic Acid; Food, Fortified; Hemoglobins; Humans; Iron; Iron Deficiencies; Male; Sodium; Structure-Activity Relationship | 1978 |
Methyldopa binding to cells in culture.
Topics: Acetaminophen; Allopurinol; Animals; Ascorbic Acid; Carcinoma, Hepatocellular; Cells, Cultured; Deferoxamine; Dimethylnitrosamine; Edetic Acid; Furosemide; Glutathione; Liver Neoplasms; Maleates; Methyldopa; Neoplasms, Experimental; Protein Binding; Rats; Superoxide Dismutase; Time Factors; Xanthines | 1977 |
Pharmacist involvement in a deferoxamine education program for patients with Cooley's anemia.
Topics: Ascorbic Acid; Asepsis; Deferoxamine; Drug Therapy, Combination; Evaluation Studies as Topic; Humans; Infusions, Parenteral; Injections, Subcutaneous; New York; Patient Education as Topic; Pharmacy Service, Hospital; Self Administration; Syringes; Thalassemia | 1979 |
Iron chelation therapy in sickle cell anemia.
Topics: Adolescent; Anemia, Sickle Cell; Ascorbic Acid; Blood Transfusion; Child; Deferoxamine; Erythrocyte Transfusion; Ferritins; Humans; Iron; Iron Chelating Agents; Liver Function Tests | 1979 |
[Therapy of thalassemias].
Topics: Ascorbic Acid; Blood Transfusion; Deferoxamine; Humans; Splenectomy; Thalassemia | 1979 |
Treatment of iron overload in adults with continuous parenteral desferrioxamine.
Topics: Adult; Aged; Ascorbic Acid; Biopsy, Needle; Deferoxamine; Female; Ferritins; Hemosiderosis; Humans; Infusions, Parenteral; Iron; Liver; Liver Cirrhosis; Male; Middle Aged; Primary Myelofibrosis; Transfusion Reaction | 1977 |
Evaluation of continuous desferrioxamine administration in adults with transfusional hemosiderosis.
Topics: Adult; Anemia, Sideroblastic; Ascorbic Acid; Deferoxamine; Drug Administration Schedule; Female; Hemosiderosis; Humans; Injections, Intravenous; Injections, Subcutaneous; Iron; Male; Middle Aged; Primary Myelofibrosis; Thalassemia; Transfusion Reaction | 1977 |
Intensive iron-chelation therapy with desferrioxamine in iron-loading anaemias.
Topics: Adolescent; Adult; Anemia; Ascorbic Acid; Child; Child, Preschool; Deferoxamine; Humans; Infusions, Parenteral; Injections, Intramuscular; Iron; Iron Chelating Agents | 1978 |
Excretion of iron in response to deferoxamine in sickle cell anemia.
Topics: Adolescent; Adult; Anemia, Sickle Cell; Ascorbic Acid; Blood Transfusion; Child; Deferoxamine; Erythrocyte Transfusion; Humans; Infusions, Parenteral; Iron | 1978 |
Iron chelation therapy with deferoxamine in Cooley anemia.
Topics: Adolescent; Adult; Ascorbic Acid; Child; Child, Preschool; Deferoxamine; Female; Humans; Infusions, Parenteral; Injections, Intramuscular; Iron; Thalassemia | 1978 |
Cooley anemia: high transfusion regimen and chelation therapy, results, and perspective.
Topics: Adolescent; Ascorbic Acid; Blood Transfusion; Child; Child, Preschool; Deferoxamine; Erythrocyte Transfusion; Female; Humans; Infusions, Parenteral; Injections, Intramuscular; Iron; Male; Thalassemia | 1978 |
Continuous intravenous deferoxamine infusion. Treatment of secondary hemochromatosis in adults.
Topics: Administration, Oral; Adult; Aged; Ascorbic Acid; Deferoxamine; Female; Hemochromatosis; Humans; Infusions, Parenteral; Iron; Male; Middle Aged; Time Factors | 1978 |
[Further experiences with iron-chelating therapy (desferrioxamine and ascorbic acid) in siderochromatosis and Cooley's disease].
Topics: Adolescent; Adult; Aged; Ascorbic Acid; Deferoxamine; Drug Evaluation; Female; Hemochromatosis; Hemosiderosis; Humans; Iron; Male; Middle Aged; Thalassemia | 1978 |
Chronic iron overload: new chelators and new strategies.
Topics: Anemia, Sideroblastic; Animals; Ascorbic Acid; Chelating Agents; Deferoxamine; Hemosiderosis; Humans; Iron; Metabolic Diseases; Thalassemia | 1978 |
Safety of intensive chelation therapy.
Topics: Adolescent; Adult; Ascorbic Acid; Deferoxamine; Drug Synergism; Humans; Siderosis | 1977 |
Total management of thalassaemia major.
Topics: Adolescent; Adult; Ascorbic Acid; Child; Child, Preschool; Deferoxamine; Humans; Hypersplenism; Infant; Iron; Splenectomy; Thalassemia; Transfusion Reaction; United Kingdom | 1977 |
Continuous subcutaneous administration of deferoxamine in patients with iron overload.
Topics: Administration, Oral; Adolescent; Adult; Aged; Ascorbic Acid; Child; Child, Preschool; Deferoxamine; Humans; Injections, Intramuscular; Injections, Subcutaneous; Iron; Middle Aged; Siderosis; Thalassemia; Time Factors | 1977 |
Iron absorption by humans from fish.
Topics: Anemia, Hypochromic; Ascorbic Acid; Deferoxamine; Diet; Fish Products; Humans; Intestinal Absorption; Iron | 1975 |
Kinetics of superoxide scavenging by dismutase enzymes and manganese mimics determined by electron spin resonance.
Topics: Ascorbic Acid; Cyclic N-Oxides; Deferoxamine; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Hydrogen-Ion Concentration; Iron; Kinetics; Manganese; Manganese Compounds; Oxides; Spin Labels; Superoxide Dismutase; Superoxides | 1992 |
Iron-induced ascorbate oxidation in plasma as monitored by ascorbate free radical formation. No spin-trapping evidence for the hydroxyl radical in iron-overloaded plasma.
Topics: Ascorbic Acid; Buffers; Catalase; Deferoxamine; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Hydroxides; Hydroxyl Radical; Iron; Iron Chelating Agents; Oxidation-Reduction; Oxygen; Pentetic Acid; Superoxide Dismutase | 1992 |
Inhibition of lipid peroxidation promoted by iron(III) and ascorbate.
Topics: Animals; Antioxidants; Ascorbic Acid; Catalase; Cyclic N-Oxides; Deferoxamine; Edetic Acid; Iron; Kinetics; Lipid Peroxidation; Microsomes, Liver; Oxygen; Rats; Sodium-Potassium-Exchanging ATPase | 1992 |
Photosensitized formation of ascorbate radicals by chloroaluminum phthalocyanine tetrasulfonate: an electron spin resonance study.
Topics: Ascorbic Acid; Catalase; Deferoxamine; Deuterium; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Free Radicals; Indoles; Organometallic Compounds; Oxygen; Photochemistry; Singlet Oxygen; Superoxide Dismutase; Superoxides | 1992 |
Comparison of ascorbic acid and ascorbic acid 2-O-alpha-glucoside on the cytotoxicity and bioavailability to low density cultures of fibroblasts.
Topics: Animals; Ascorbic Acid; Biological Availability; Catalase; Cell Count; Cell Survival; Cells, Cultured; Chick Embryo; Collagen; Deferoxamine; Female; Fibroblasts; Humans; Infant; Intracellular Fluid; Kinetics; Reactive Oxygen Species; Skin; Vitamin E | 1992 |
Prevention by Ginkgo biloba extract (EGb 761) and trolox C of the decrease in synaptosomal dopamine or serotonin uptake following incubation.
Topics: Animals; Ascorbic Acid; Chromans; Corpus Striatum; Deferoxamine; Dopamine; Drug Interactions; Ginkgo biloba; In Vitro Techniques; Male; Mice; Plant Extracts; Quercetin; Serotonin; Synaptosomes; Tritium | 1992 |
Increased susceptibility of the sickle cell membrane Ca2+ + Mg(2+)-ATPase to t-butylhydroperoxide: protective effects of ascorbate and desferal.
Topics: Anemia, Sickle Cell; Ascorbic Acid; Ca(2+) Mg(2+)-ATPase; Calcium-Transporting ATPases; Calmodulin; Deferoxamine; Erythrocyte Membrane; Ethylmaleimide; Hemoglobins; Humans; Iron; Kinetics; Malondialdehyde; Membrane Proteins; Molecular Weight; Oxidation-Reduction; Peroxides; Polymers; tert-Butylhydroperoxide | 1992 |
Desferal-Mn(III) in the therapy of diquat-induced cataract in rabbit.
Topics: Animals; Ascorbic Acid; Cataract; Deferoxamine; Diquat; Free Radicals; Glutathione; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Kinetics; Lens, Crystalline; Lipid Peroxidation; Malondialdehyde; Membrane Lipids; Organ Culture Techniques; Organometallic Compounds; Rabbits | 1991 |
Hydroxyl radical formation by sickle erythrocyte membranes: role of pathologic iron deposits and cytoplasmic reducing agents.
Topics: Anemia, Sickle Cell; Ascorbic Acid; Deferoxamine; Erythrocyte Membrane; Free Radicals; Glutathione; Heme; Humans; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Iron; Kinetics; Lipid Peroxidation; NAD; NADP; Oxidation-Reduction; Reference Values | 1991 |
The action of hydrogen peroxide on the formation of thiobarbituric acid-reactive material from microsomes, liposomes or from DNA damaged by bleomycin or phenanthroline. Artefacts in the thiobarbituric acid test.
Topics: Animals; Ascorbic Acid; Bleomycin; Chlorides; Cytochrome P-450 Enzyme Inhibitors; Deferoxamine; DNA; DNA Damage; Edetic Acid; Ferric Compounds; Hydrogen Peroxide; Lipid Peroxidation; Liposomes; Male; Microsomes, Liver; Phenanthrolines; Rats; Thiobarbiturates | 1990 |
Effectiveness of some chelating agents on distribution and excretion of vanadium in rats after prolonged oral administration.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Administration, Oral; Animals; Ascorbic Acid; Chelating Agents; Deferoxamine; Male; Rats; Rats, Inbred Strains; Thiomalates; Tissue Distribution; Vanadates; Vanadium; Vanadium Compounds | 1991 |
The antibacterial activity of a siderophore. 2. The influence of deferoxamine alone and combined with ascorbic acid on the activity of antibiotics against Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Ascorbic Acid; Cephalothin; Colony Count, Microbial; Deferoxamine; Drug Interactions; Iron Chelating Agents; Microbial Sensitivity Tests; Staphylococcus aureus | 1991 |
Effects of alloxan and reducing agents on macrophages in culture.
Topics: Alloxan; Animals; Ascorbic Acid; Catalase; Cell Death; Cell Line; Cell Survival; Cysteine; Deferoxamine; Free Radicals; Macrophages; Mice; Oxygen Consumption; Superoxide Dismutase | 1991 |
The effect of iron and iron chelators on the in-vitro block to development of the mouse preimplantation embryo: BAT6 a new medium for improved culture of mouse embryos in vitro.
Topics: Animals; Apoproteins; Ascorbic Acid; Cell Division; Culture Media; Culture Techniques; Deferoxamine; Dose-Response Relationship, Drug; Edetic Acid; Embryo, Mammalian; Embryonic Development; Female; Ferrous Compounds; Iron; Iron Chelating Agents; Mice; Pentetic Acid; Pregnancy; Transferrin | 1990 |
Prooxidant action of desferrioxamine: enhancement of alkaline phosphatase inactivation by interaction with ascorbate system.
Topics: Alkaline Phosphatase; Ascorbic Acid; Deferoxamine; Free Radicals; Hydroxides; Hydroxyl Radical; Kinetics; Nitroblue Tetrazolium; Oxidation-Reduction; Superoxide Dismutase | 1990 |
The catalytic activity of iron in synovial fluid as monitored by the ascorbate free radical.
Topics: Ascorbic Acid; Deferoxamine; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Iron; Oxidation-Reduction; Pentetic Acid; Synovial Fluid; Synovitis, Pigmented Villonodular | 1990 |
Radioprotection by ascorbic acid, desferal, and mercaptoethylamine.
Topics: Animals; Ascorbic Acid; Deferoxamine; Dose-Response Relationship, Radiation; Female; Free Radicals; Gamma Rays; Hydroxides; Hydroxyl Radical; Male; Mercaptoethylamines; Mice; Mice, Inbred Strains; Peroxides; Radiation-Protective Agents; X-Rays | 1990 |
Autophagic degradation of protein generates a pool of ferric iron required for the killing of cultured hepatocytes by an oxidative stress.
Topics: Adenine; Amino Acids; Animals; Ascorbic Acid; Autophagy; Benzyl Alcohol; Benzyl Alcohols; Cell Survival; Cells, Cultured; Colchicine; Deferoxamine; Ferric Compounds; Ferritins; Liver; Methylamines; Oligomycins; Oligopeptides; Oxidation-Reduction; Peroxides; Phagocytosis; Proteins; Rats; Rats, Inbred Strains; tert-Butylhydroperoxide | 1990 |
Reactive oxygen species induce antigenic changes in DNA.
Topics: Animals; Antibodies; Ascorbic Acid; Cattle; Deferoxamine; DNA; Epitopes; Free Radicals; Humans; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Immune Sera; Immunoglobulin A; Immunoglobulin G; Immunoglobulin Isotypes; Immunoglobulin M; Lupus Erythematosus, Systemic; Nucleic Acid Denaturation; Oxygen; Thiourea | 1989 |
Characterization of a superoxide dismutase mimic prepared from desferrioxamine and MnO2.
Topics: Ascorbic Acid; Cations; Chelating Agents; Chemical Phenomena; Chemistry; Deferoxamine; Edetic Acid; Manganese; Manganese Compounds; Oxidation-Reduction; Oxides; Spectrophotometry, Infrared; Spectrum Analysis; Superoxide Dismutase | 1989 |
Oxygen reduction and lipid peroxidation by iron chelates with special reference to ferric nitrilotriacetate.
Topics: Adenosine Diphosphate; Animals; Ascorbic Acid; Deferoxamine; Edetic Acid; Ferric Compounds; Iron Chelating Agents; Linoleic Acid; Linoleic Acids; Lipid Peroxidation; Liposomes; Membrane Lipids; Micelles; Microsomes, Liver; NADP; Nitrilotriacetic Acid; Oxidation-Reduction; Oxygen; Pentetic Acid; Rats; Rats, Inbred Strains | 1989 |
Hydrogen peroxide cytotoxicity. Low-temperature enhancement by ascorbate or reduced lipoate.
Topics: Animals; Ascorbic Acid; Cell Line; Cell Survival; Cold Temperature; Deferoxamine; Dehydroascorbic Acid; DNA Replication; Drug Synergism; Epithelial Cells; Epithelium; Hydrogen Peroxide; Oxidation-Reduction; Thioctic Acid; Thymidine | 1989 |
Prooxidant and antioxidant effects of ascorbate on tBuOOH-induced erythrocyte membrane damage.
Topics: Antioxidants; Ascorbic Acid; Deferoxamine; Erythrocyte Membrane; Ethylmaleimide; Humans; In Vitro Techniques; Kinetics; Lipid Peroxidation; Oxidation-Reduction; Peroxides; Sulfhydryl Compounds; tert-Butylhydroperoxide; Thiobarbiturates | 1989 |
The antibacterial activity of a siderophore. 1. In vitro activity of deferoxamine alone and in combination with ascorbic acid on Staphylococcus aureus.
Topics: Ascorbic Acid; Deferoxamine; Dose-Response Relationship, Drug; Ferric Compounds; In Vitro Techniques; Microbial Sensitivity Tests; Staphylococcus aureus | 1989 |
The interactions of desferrioxamine and hydroxypyridone compounds with haemoglobin and erythrocytes.
Topics: Ascorbic Acid; Biological Transport; Cell Membrane Permeability; Chelating Agents; Deferoxamine; Erythrocyte Membrane; Ferrous Compounds; Hemoglobins; Humans; Hydrogen Peroxide; Hydroxylation; Oxidation-Reduction; Pyridones | 1989 |
The suppression of iron release from activated myoglobin by physiological electron donors and by desferrioxamine.
Topics: Ascorbic Acid; Deferoxamine; Electron Transport; Hydrogen Peroxide; Iron; Lipid Peroxides; Myoglobin; Spectrophotometry, Ultraviolet | 1989 |
Hemoglobin-mediated oxidant damage to the central nervous system requires endogenous ascorbate.
Topics: Animals; Ascorbic Acid; Brain; Cerebrovascular Circulation; Deferoxamine; Hemoglobins; Hemorrhage; Lipid Peroxides; Male; Mice; Oxidation-Reduction; Sodium-Potassium-Exchanging ATPase; Thiobarbiturates | 1988 |
Ascorbate autoxidation in the presence of iron and copper chelates.
Topics: Ascorbic Acid; Cation Exchange Resins; Chelating Agents; Copper; Deferoxamine; Edetic Acid; Iron Chelating Agents; Oxidation-Reduction; Pentetic Acid; Resins, Synthetic; Superoxides | 1986 |
The iron chelators desferrioxamine and 1-alkyl-2-methyl-3-hydroxypyrid-4-ones inhibit vascular prostacyclin synthesis in vitro.
Topics: Aluminum; Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Ascorbic Acid; Calcimycin; Deferiprone; Deferoxamine; Epinephrine; Epoprostenol; Hydrogen Peroxide; Iron; Iron Chelating Agents; Male; Pyridones; Rats; Rats, Inbred Strains | 1988 |
Desferrioxamine and ascorbic acid supplement in E-B thalassaemia.
Topics: Ascorbic Acid; Child; Child, Preschool; Deferoxamine; Humans; Thalassemia | 1988 |
Effectiveness of chelation therapy with time after acute vanadium intoxication.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Animals; Ascorbic Acid; Chelating Agents; Deferoxamine; Feces; Male; Mice; Time Factors; Tissue Distribution; Vanadium | 1988 |
Radioprotection of mice with ascorbic acid, desferal and mercaptoethylamine.
Topics: Animals; Ascorbic Acid; Cobalt Radioisotopes; Deferoxamine; Dose-Response Relationship, Radiation; Mercaptoethylamines; Mice; Mice, Inbred BALB C; Radiation Protection | 1988 |
Oral ascorbic acid and iron excretion in thalassemic children treated with desferrioxamine-methansulfonate (Desferal).
Topics: Administration, Oral; Adolescent; Ascorbic Acid; Child; Child, Preschool; Deferoxamine; Drug Therapy, Combination; Humans; Iron; Thalassemia | 1988 |
The effects of ascorbic acid on the intracellular metabolism of iron and ferritin.
Topics: Animals; Ascorbic Acid; Cell Line; Deferoxamine; Dose-Response Relationship, Drug; Ferritins; Iron; Leukemia, Erythroblastic, Acute; Leupeptins; Methionine | 1986 |
Iron-mediated oxidative stress in erythrocytes.
Topics: Adenosine Triphosphate; Ascorbic Acid; Deferoxamine; Erythrocyte Membrane; Erythrocytes; Glutathione; Humans; Hydrogen Peroxide; In Vitro Techniques; Iron; Oxidation-Reduction | 1987 |
Iron chelation using subcutaneous infusions of diethylene triamine penta-acetic acid (DTPA).
Topics: Administration, Oral; Adult; Ascorbic Acid; Child; Deferoxamine; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Injections, Subcutaneous; Iron; Iron Chelating Agents; Male; Pentetic Acid; Sulfates; Thalassemia; Transfusion Reaction; Zinc; Zinc Sulfate | 1986 |
Sickle cell membranes and oxidative damage.
Topics: Anemia, Sickle Cell; Antioxidants; Ascorbic Acid; Deferoxamine; Erythrocyte Membrane; Erythrocytes, Abnormal; Free Radicals; Humans; In Vitro Techniques; Iron; Oxidation-Reduction | 1986 |
Oxidative effects of iron on erythrocytes.
Topics: Ascorbic Acid; Deferoxamine; Erythrocytes; Ferrous Compounds; Free Radicals; Humans; Hydrogen Peroxide; In Vitro Techniques; Iron; Methemoglobin; Oxidation-Reduction | 1985 |
Iron metabolism by reticuloendothelial cells in vitro. Physical and chemical conditions, lipotrope deficiency, and acute inflammation.
Topics: Animals; Ascorbic Acid; Cobalt; Copper; Cysteine; Dactinomycin; Deferoxamine; Dinitrophenols; Edetic Acid; Fatty Liver; Fluorides; Fructose; Glucose; Glutathione; Hemochromatosis; Inflammation; Iodoacetates; Iron; Lipotropic Agents; Liver Cirrhosis; Lung; Macrophages; Microscopy, Electron; Potassium Permanganate; Protein Biosynthesis; Puromycin; Rabbits; RNA; Saponins; Sucrose; Surface-Active Agents; Transferrin; Trypsin | 1969 |
[Siderinuria caused by deferoxamine. II. The siderinuric increment obtained by association with ascorbic acid].
Topics: Adolescent; Adult; Aged; Anemia; Ascorbic Acid; Child, Preschool; Deferoxamine; Drug Therapy, Combination; Female; Humans; Iron; Liver Diseases; Lymphoma; Male; Middle Aged | 1973 |
Food iron absorption in man. 3. Effect of iron salt, ascorbic acid and desferrioxamine on the isotopic exchange between native food iron and an extrinsic inorganic iron tracer.
Topics: Ascorbic Acid; Deferoxamine; Depression, Chemical; Female; Hematocrit; Hemoglobins; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Ion Exchange; Iron; Iron Radioisotopes; Male; Methods; Stimulation, Chemical; Time Factors; Triticum; Whole-Body Counting; Zea mays | 1973 |
Lipid peroxide formation in microsomes. The role of non-haem iron.
Topics: Animals; Ascorbic Acid; Deferoxamine; Edetic Acid; In Vitro Techniques; Iron; Lipid Metabolism; Microsomes; NADP; Peroxides; Phenanthrolines; Rats; Sucrose | 1969 |
The identification of 2, 3-dihydroxybenzoic acid as a potentially useful iron-chelating drug.
Topics: Administration, Oral; Animals; Ascorbic Acid; Benzoates; Blood Transfusion; Body Weight; Calcium; Carboxylic Acids; Catechols; Chelating Agents; Copper; Deferoxamine; Disease Models, Animal; Feces; Hemochromatosis; Hydroxylation; Injections, Intraperitoneal; Iron; Iron Chelating Agents; Iron Radioisotopes; Lethal Dose 50; Magnesium; Mice; Mice, Inbred Strains; Rats; Zinc | 1974 |
Ascorbic acid enhancement of desferrioxamine-induced urinary iron excretion in thalassemia major.
Topics: Administration, Oral; Adolescent; Adult; Age Factors; Ascorbic Acid; Child; Child, Preschool; Deferoxamine; Drug Synergism; Humans; Iron; Thalassemia; Transfusion Reaction | 1974 |
Long-term desferrioxamine therapy in thalassemia.
Topics: Adolescent; Ascorbic Acid; Child; Child, Preschool; Cyprus; Deferoxamine; Drug Synergism; Humans; Iron; Liver; Thalassemia; Time Factors; Transfusion Reaction | 1974 |
Plutonium uptake by cell cultures in presence of some chelating agents.
Topics: Acetone; Ascorbic Acid; Cell Line; Chelating Agents; Chondroitin; Citrates; Deferoxamine; HeLa Cells; Humans; Iron Radioisotopes; Liver; Pentetic Acid; Plutonium; Sodium | 1973 |
Editorial: Thalassemia major: a problem of iron overload.
Topics: Ascorbic Acid; Chelating Agents; Child; Child, Preschool; Deferoxamine; Humans; Intestinal Absorption; Iron; Pentetic Acid; Thalassemia; Transfusion Reaction | 1974 |
Determination of iron in solutions containing iron complexes.
Topics: Ascorbic Acid; Autoanalysis; Deferoxamine; Edetic Acid; Ferritins; Hemoglobins; Humans; Iron; Potassium Permanganate | 1969 |
A study of iron transfer from rabbit transferrin to reticulocytes using synthetic chelating agents.
Topics: Acetates; Animals; Arsenic; Ascorbic Acid; Biological Transport; Bone Marrow; Bone Marrow Cells; Cell Membrane; Chelating Agents; Citrates; Deferoxamine; Dialysis; Dinitrophenols; Edetic Acid; Erythrocytes; Female; Glutathione; Hemoglobins; Imines; Iron; Iron Chelating Agents; Iron Isotopes; Kinetics; Nitriles; Phenanthrolines; Pyridines; Rabbits; Reticulocytes; Rotenone; Sulfhydryl Reagents; Temperature; Transferrin | 1971 |
New method for determining total iron-binding capacity of serum (TIBC) with radioiron by eliminating iron from transferrin.
Topics: Ascorbic Acid; Bicarbonates; Centrifugation; Citrates; Deferoxamine; Humans; Hydrogen-Ion Concentration; Ion Exchange Resins; Iron; Iron Isotopes; Methods; Protein Binding; Quaternary Ammonium Compounds; Sodium; Transferrin | 1971 |
The effect of ascorbic acid deficiency on desferrioxamine-induced urinary iron excretion.
Topics: Ascorbic Acid; Ascorbic Acid Deficiency; Deferoxamine; Hemochromatosis; Humans; Iron; Leukocytes; Male; Siderosis; Transfusion Reaction | 1969 |
Iron overload in haemochromatosis.
Topics: Adult; Arthritis; Ascorbic Acid; Biopsy; Bloodletting; Deferoxamine; Female; Gastric Juice; Hemochromatosis; Humans; Intestinal Absorption; Iron; Liver; Male; Middle Aged | 1970 |
Effect of ascorbic acid on desferrioxamine therapy.
Topics: Adult; Anemia, Macrocytic; Ascorbic Acid; Deferoxamine; Humans; Iron; Male | 1970 |
Automated determination of serum iron and ferrioxamine in urine.
Topics: Ascorbic Acid; Autoanalysis; Deferoxamine; Humans; Iron; Methods; Phenanthrolines; Protein Binding | 1971 |
Iron absorption from veal muscle.
Topics: Adolescent; Adult; Animals; Ascorbic Acid; Cattle; Child; Chromatography, Gel; Citrates; Deferoxamine; Depression, Chemical; Female; Hematocrit; Hemoglobins; Humans; Intestinal Absorption; Iron; Iron Isotopes; Male; Meat; Middle Aged; Muscles; Rabbits; Stimulation, Chemical; Transferrin; Vegetables; Venezuela; Zea mays | 1971 |
Observations on the mechanism of iron absorption.
Topics: Adolescent; Adult; Ascorbic Acid; Chelating Agents; Child; Deferoxamine; Female; Ferritins; Glycine max; Hemoglobins; Humans; Intestinal Absorption; Iron; Male; Middle Aged; Triticum; Zea mays | 1968 |
Inhibition of bacterial multiplication by the iron chelator deferoxamine: potentiating effect of ascorbic acid.
Topics: Alcaligenes; Ascorbic Acid; Bacteria; Deferoxamine; Dose-Response Relationship, Drug; Drug Synergism; Enterobacteriaceae; Ferric Compounds; Neisseria meningitidis; Pseudomonas; Staphylococcus | 1983 |
Cleavage of DNA with methidiumpropyl-EDTA-iron(II): reaction conditions and product analyses.
Topics: Animals; Ascorbic Acid; Catalase; Cattle; Deferoxamine; Dithiothreitol; DNA; DNA, Superhelical; Edetic Acid; Metals; Plasmids; Spectrophotometry; Superoxide Dismutase | 1984 |
Effect of ascorbic acid on desferrioxamine-induced urinary iron excretion in idiopathic hemochromatosis.
Topics: Adult; Ascorbic Acid; Deferoxamine; Female; Hemochromatosis; Humans; Iron; Male; Middle Aged; Time Factors | 1984 |
Vitamin C, desferrioxamine and iron loading anemias.
Topics: Anemia; Ascorbic Acid; Deferoxamine; Genes, Recessive; Hemochromatosis; Humans; Intestinal Absorption; Iron; Transfusion Reaction | 1984 |
Desferrioxamine-induced iron outputs in Cooley's anemia. Results and perspectives.
Topics: Adolescent; Ascorbic Acid; Blood Transfusion; Child; Deferoxamine; Female; Humans; Iron; Male; Splenectomy; Thalassemia | 1981 |
Survival and desferrioxamine in thalassaemia major.
Topics: Adult; Ascorbic Acid; Deferoxamine; Humans; Iron; Thalassemia | 1982 |
Ascorbic acid, iron overload, and desferrioxamine.
Topics: Ascorbic Acid; Deferoxamine; Drug Therapy, Combination; Humans; Iron | 1982 |
Effect of ferritin-containing fractions with different iron loading on lipid peroxidation.
Topics: Ascorbic Acid; Deferoxamine; Ferritins; Iron; Lipid Peroxides; Liposomes; Membrane Lipids; Pentetic Acid | 1983 |
The management of iron chelation therapy.
Topics: Anemia, Hemolytic, Congenital; Ascorbic Acid; Child; Child, Preschool; Deferoxamine; Drug Administration Schedule; Humans; Infusions, Parenteral; Iron; Thalassemia; Time Factors | 1983 |
Evaluation of cardiac function in patients with thalassemia major.
Topics: Adolescent; Adult; Ascorbic Acid; Child; Child, Preschool; Deferoxamine; Heart; Heart Diseases; Heart Failure; Heart Function Tests; Humans; Iron; Thalassemia; Transfusion Reaction | 1980 |
Clinical management of thalassemia. Decreasing iron stores during intensive chelation therapy.
Topics: Ascorbic Acid; Blood Transfusion; Child; Deferoxamine; Erythrocyte Transfusion; Humans; Iron; Male; Thalassemia | 1980 |
Chelation therapy, transfusion requirement, and iron balance in young thalassemic patients.
Topics: Adolescent; Ascorbic Acid; Blood Transfusion; Child; Child, Preschool; Deferoxamine; Erythrocyte Transfusion; Humans; Iron; Splenectomy; Thalassemia | 1980 |
Ferrioxamine excretion in iron-loaded man.
Topics: Adult; Ascorbic Acid; Deferoxamine; Dose-Response Relationship, Drug; Feces; Hemosiderosis; Humans; Intestinal Absorption; Iron; Thalassemia; Transfusion Reaction | 1982 |
Effect of subcutaneous deferoxamine and oral vitamin C on iron excretion in congenital hypoplastic anemia and refractory anemia associated with the 5q-syndrome.
Topics: Administration, Oral; Anemia, Aplastic; Ascorbic Acid; Blood Transfusion; Child; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 4-5; Deferoxamine; Female; Hemosiderosis; Humans; Injections, Subcutaneous; Iron; Male; Middle Aged; Syndrome | 1982 |
Ascorbic acid and iron levels in plasma and liver of vitamin C deficient guinea pigs after iron overload and desferrioxamine administration.
Topics: Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Deferoxamine; Dose-Response Relationship, Drug; Female; Ferrous Compounds; Guinea Pigs; Iron; Liver | 1982 |
Experimental siderosis of articular chondrocytes cultured in vitro.
Topics: Animals; Ascorbic Acid; Cartilage, Articular; Cattle; Cells, Cultured; Deferoxamine; Disease Models, Animal; Erythrocytes; Ferrous Compounds; Iron; Organ Culture Techniques; Phagocytes; Rabbits; Siderosis | 1981 |
Release of iron by resident and stimulated mouse peritoneal macrophages following ingestion and degradation of transferrin-antitransferrin immune complexes.
Topics: Animals; Antigen-Antibody Complex; Apoproteins; Ascitic Fluid; Ascorbic Acid; Cells, Cultured; Deferoxamine; Iodine Radioisotopes; Iron; Iron Radioisotopes; Macrophages; Mice; Transferrin | 1981 |
Vitamin C and iron.
Topics: Administration, Oral; Adult; Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Deferoxamine; Female; Guinea Pigs; Hemosiderosis; Humans; Injections, Subcutaneous; Iron; Male; Scurvy; Thalassemia; Transfusion Reaction | 1981 |
The effect of various antioxidants and other modifying agents on oxygen-radical-generated DNA damage in human lymphocytes in the COMET assay.
Topics: Adult; Antioxidants; Apoproteins; Ascorbic Acid; Bleomycin; Catalase; Cells, Cultured; Deferoxamine; DNA Damage; Drug Interactions; Female; Ferrous Compounds; Humans; Hydrogen Peroxide; Lymphocytes; Male; Mannitol; Mutagenicity Tests; Reactive Oxygen Species; Silymarin; Smoking; Superoxide Dismutase; Transferrin; Vitamin E | 1994 |
Singlet oxygen-trapping reaction as a method of (1)O2 detection: role of some reducing agents.
Topics: Ascorbic Acid; Cations; Cyclic N-Oxides; Deferoxamine; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Iron; Oxidation-Reduction; Oxygen; Piperidones; Reactive Oxygen Species; Triacetoneamine-N-Oxyl; Ultraviolet Rays; Xanthine Oxidase | 1995 |
High susceptibility to paraquat-driven lipid peroxidation of cultured hepatocytes loaded with linolenic acid.
Topics: alpha-Linolenic Acid; Animals; Antioxidants; Ascorbic Acid; Cells, Cultured; Deferoxamine; Fatty Acids, Unsaturated; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Lipid Peroxidation; Liver; Male; Paraquat; Rats; Rats, Wistar | 1995 |
Relationship of the metabolism of vitamins C and E in cultured hepatocytes treated with tert-butyl hydroperoxide.
Topics: Animals; Antioxidants; Ascorbic Acid; Cells, Cultured; Deferoxamine; DNA Damage; DNA, Single-Stranded; Lipid Peroxidation; Liver; Male; Peroxides; Phenylenediamines; Rats; Rats, Sprague-Dawley; tert-Butylhydroperoxide; Vitamin E | 1995 |
Effects of magnesium and iron on lipid peroxidation in cultured hepatocytes.
Topics: Animals; Ascorbic Acid; Cells, Cultured; Culture Media; Deferoxamine; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Ferrous Compounds; Free Radicals; Lipid Peroxidation; Liver; Magnesium; Malondialdehyde; Rats; Reactive Oxygen Species; Time Factors | 1995 |
DNA base modifications and membrane damage in cultured mammalian cells treated with iron ions.
Topics: Animals; Ascorbic Acid; Cell Membrane; Cell Membrane Permeability; Cells, Cultured; Deferoxamine; Dimethyl Sulfoxide; DNA Damage; Ferrous Compounds; Free Radical Scavengers; Gas Chromatography-Mass Spectrometry; Hydroxyl Radical; Mice; Purines; Pyrimidines; Spectrometry, Fluorescence | 1995 |
The in vivo cytoprotection of ascorbic acid against ischemia/reoxygenation injury of rat liver.
Topics: Adenosine Triphosphate; Alanine Transaminase; Animals; Ascorbic Acid; Aspartate Aminotransferases; Deferoxamine; Dehydroascorbic Acid; Dose-Response Relationship, Drug; Glutathione; Iron; Ischemia; Kinetics; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Male; Rats; Rats, Wistar; Reperfusion Injury; Thiobarbituric Acid Reactive Substances; Time Factors | 1995 |
Phycobilin biosynthesis: reductant requirements and product identification for heme oxygenase from Cyanidium caldarium.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Ascorbic Acid; Biliverdine; Deferoxamine; Dithiothreitol; Ferredoxins; Heme Oxygenase (Decyclizing); Iron Chelating Agents; Mesoporphyrins; Molecular Structure; Myoglobin; Oxidation-Reduction; Phycobilins; Phycocyanin; Pyrroles; Rhodophyta; Solubility; Spectrophotometry; Tetrapyrroles | 1995 |
The effects of desferrioxamine and ascorbate on oxidative stress in the streptozotocin diabetic rat.
Topics: Animals; Ascorbic Acid; Blood Glucose; Cholesterol; Copper; Deferoxamine; Diabetes Mellitus, Experimental; Erythrocyte Membrane; Glycated Hemoglobin; Glycated Serum Albumin; Glycation End Products, Advanced; Humans; Insulin; Insulin, Regular, Pork; Iron; Liver; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Recombinant Proteins; Reference Values; Serum Albumin; Triglycerides; Vitamin A; Vitamin E | 1995 |
Spectrophotometric determination of dehydroascorbic acid in biological samples.
Topics: 3T3 Cells; Animals; Ascorbic Acid; Chromatography, High Pressure Liquid; Deferoxamine; Dehydroascorbic Acid; Edetic Acid; Fibroblasts; Humans; Indicators and Reagents; Lymphocytes; Mammals; Mice; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry | 1994 |
Influence of iron, deferoxamine and ascorbic acid on gentamicin-induced nephrotoxicity in rats.
Topics: Animals; Ascorbic Acid; Blood Urea Nitrogen; Creatinine; Deferoxamine; Dose-Response Relationship, Drug; Drug Synergism; Female; Gentamicins; Iron; Kidney Tubules, Proximal; Necrosis; Rats; Rats, Sprague-Dawley | 1994 |
Tyrosinase-induced phenoxyl radicals of etoposide (VP-16): interaction with reductants in model systems, K562 leukemic cell and nuclear homogenates.
Topics: Ascorbic Acid; Cell Nucleus; Chromatography, High Pressure Liquid; Deferoxamine; Electron Spin Resonance Spectroscopy; Etoposide; Free Radicals; Glutathione; Humans; Leukemia; Monophenol Monooxygenase; Oxidation-Reduction; Phenols; Thioctic Acid; Tumor Cells, Cultured | 1993 |
The antibacterial activity of a siderophore. 3. The activity of deferoxamine in vitro and its influence on the effect of antibiotics against Escherichia coli, Proteus mirabilis and coagulase-negative staphylococci.
Topics: Anti-Bacterial Agents; Ascorbic Acid; Cephalothin; Deferoxamine; Drug Interactions; Drug Synergism; Escherichia coli; Gentamicins; Humans; Microbial Sensitivity Tests; Proteus mirabilis; Staphylococcus; Staphylococcus epidermidis; Urine | 1994 |
Bimodal pattern of killing of Chinese hamster V79 variant cells by hydrogen peroxide.
Topics: Animals; Ascorbic Acid; Benzene Derivatives; Catalase; Cell Line; Cell Survival; Chelating Agents; Clone Cells; Cricetinae; Cricetulus; Deferoxamine; Dose-Response Relationship, Drug; Drug Resistance; Glucosephosphate Dehydrogenase; Glutathione Peroxidase; Hydrogen Peroxide; Kinetics; Peroxides; Phenanthrolines; Reactive Oxygen Species; Superoxide Dismutase; tert-Butylhydroperoxide | 1994 |
Induction of oxidative single- and double-strand breaks in DNA by ferric citrate.
Topics: Ascorbic Acid; Catalase; Cysteine; Deferoxamine; DNA Damage; DNA, Superhelical; Ferric Compounds; Free Radical Scavengers; Hydrogen Peroxide; Hydrogen-Ion Concentration; Osmolar Concentration; Plasmids; Superoxides | 1993 |
Antioxidant defenses and its modulation by iron in carrageenan-induced inflammation in rats.
Topics: Animals; Antioxidants; Ascorbic Acid; Carrageenan; Deferoxamine; Disease Models, Animal; Granuloma; Male; Rats; Rats, Sprague-Dawley; Uric Acid; Vitamin A | 1993 |
Effect of tert-butyl hydroperoxide addition on spontaneous chemiluminescence in brain.
Topics: Animals; Antioxidants; Ascorbic Acid; Brain; Deferoxamine; Edetic Acid; Female; Histocytochemistry; Iron; Lipid Peroxidation; Luminescent Measurements; Malondialdehyde; NADPH-Ferrihemoprotein Reductase; Peroxides; Rats; Rats, Wistar; tert-Butylhydroperoxide; Thiobarbituric Acid Reactive Substances | 1995 |
Antioxidant and iron-chelating agents in cerebral vasospasm.
Topics: Animals; Antioxidants; Ascorbic Acid; Deferoxamine; Dose-Response Relationship, Drug; Femoral Artery; Free Radicals; Iron; Iron Chelating Agents; Ischemic Attack, Transient; Male; Pregnatrienes; Rats; Rats, Sprague-Dawley; Thrombosis; Vascular Resistance | 1995 |
Differential effects of in vitro peroxidation on peripheral- and central-type benzodiazepine receptors. Protection by diverse antioxidants.
Topics: Animals; Antioxidants; Ascorbic Acid; Benzodiazepinones; Brain; Cell Membrane; Chromans; Deferoxamine; Edetic Acid; Ferrous Compounds; Flunitrazepam; Hypolipidemic Agents; Lipid Peroxidation; Liver; Malondialdehyde; Receptors, GABA-A; Rutin; Vitamin E | 1995 |
The iron-selective chelator desferal can reduce chelated copper.
Topics: Animals; Ascorbic Acid; Copper; Cricetinae; Deferoxamine; Oxidation-Reduction; Siderophores | 1996 |
Ascorbate-stimulated lipid peroxidation in human brain is dependent on iron but not on hydroxyl radical.
Topics: Adult; Ascorbic Acid; Brain; Catalase; Caudate Nucleus; Cerebellum; Cerebral Cortex; Chelating Agents; Deferoxamine; Free Radical Scavengers; Humans; Hydroxyl Radical; Iron; Lipid Peroxides; Mannitol; Middle Aged; Oxidation-Reduction; Superoxide Dismutase | 1996 |
Ascorbate promotes low density lipoprotein oxidation in the presence of ferritin.
Topics: Arteriosclerosis; Ascorbic Acid; Chelating Agents; Deferoxamine; Ferritins; Iron; Kinetics; Lipid Peroxidation; Lipoproteins, LDL | 1996 |
The effect of quinolinate on rat brain lipid peroxidation is dependent on iron.
Topics: Animals; Ascorbic Acid; Brain; Deferoxamine; Iron Chelating Agents; Lipid Peroxidation; Male; Quinolinic Acid; Rats; Rats, Wistar; Siderophores | 1997 |
Reduced susceptibility of renal slices to oxidative damage.
Topics: Animals; Antioxidants; Ascorbic Acid; Cell Survival; Deferoxamine; Glutathione; In Vitro Techniques; Kidney Cortex; Kinetics; L-Lactate Dehydrogenase; Male; Mesna; Oxidative Stress; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Vitamin E | 1997 |
Dopamine- and L-beta-3,4-dihydroxyphenylalanine hydrochloride (L-Dopa)-induced cytotoxicity towards catecholaminergic neuroblastoma SH-SY5Y cells. Effects of oxidative stress and antioxidative factors.
Topics: Ascorbic Acid; Catalase; Cell Survival; Deferoxamine; Dopamine; Levodopa; Lipid Peroxidation; Neuroblastoma; Oxidative Stress; Superoxide Dismutase; Tumor Cells, Cultured; Vitamin E | 1997 |
Instantaneous analysis of aldehydes in biological fluids using a spray interface coupled to a mass spectrometer.
Topics: Aldehydes; Animals; Ascorbic Acid; Body Fluids; Butylated Hydroxytoluene; Deferoxamine; Fatty Acids, Unsaturated; Hydroxylamines; Iron; Lipid Peroxidation; Mass Spectrometry; Myocardium; Rats | 1997 |
Cytotoxicity and apoptosis produced by arachidonic acid in Hep G2 cells overexpressing human cytochrome P4502E1.
Topics: alpha-Tocopherol; Antioxidants; Apoptosis; Ascorbic Acid; Aspirin; Carcinoma, Hepatocellular; Cell Survival; Chromans; Cytochrome P-450 CYP2E1; Deferoxamine; Humans; L-Lactate Dehydrogenase; Liver Neoplasms; Oleic Acid; Phenylenediamines; Propyl Gallate; Proto-Oncogene Proteins c-bcl-2; Recombinant Proteins; Transfection; Tumor Cells, Cultured; Vitamin E | 1997 |
Hyperpermeability of intestinal epithelial monolayers is induced by NO: effect of low extracellular pH.
Topics: Adenosine Triphosphate; Ascorbic Acid; Caco-2 Cells; Cell Membrane Permeability; Deferoxamine; Extracellular Space; Glutathione; Humans; Hydrogen; Hydrogen-Ion Concentration; Intestinal Mucosa; Microscopy, Fluorescence; Nitric Oxide | 1997 |
Protective effect of deferoxamine on chromium (VI)-induced DNA single-strand breaks, cytotoxicity, and lipid peroxidation in primary cultures of rat hepatocytes.
Topics: Alkaline Phosphatase; Animals; Antidotes; Ascorbic Acid; Caustics; Cells, Cultured; Deferoxamine; DNA Damage; DNA, Single-Stranded; Dose-Response Relationship, Drug; Glutathione; Glutathione Peroxidase; Glutathione Reductase; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Male; Malondialdehyde; Potassium Dichromate; Rats; Rats, Wistar; Superoxide Dismutase; Vitamin E | 1997 |
Mechanisms by which ascorbic acid increases ferritin levels in cultured lens epithelial cells.
Topics: Animals; Ascorbic Acid; Base Sequence; Blotting, Northern; Cells, Cultured; Deferoxamine; Dithiothreitol; DNA; Dogs; Epithelium; Ferric Compounds; Ferritins; Hydrogen Peroxide; Lens, Crystalline; Molecular Sequence Data; Oxidation-Reduction; Protein Biosynthesis; Protein Synthesis Inhibitors; RNA, Messenger | 1997 |
Effect on an iron-chelator on ascorbate-induced cytotoxicity.
Topics: Apoptosis; Ascorbic Acid; Culture Media; Deferoxamine; Free Radicals; HL-60 Cells; Humans; Oxidation-Reduction; Siderophores; Tumor Cells, Cultured | 1997 |
The efficacy of antioxidants administered during low temperature storage of warm ischemic kidney tissue slices.
Topics: Animals; Antioxidants; Ascorbic Acid; Chromans; Cryopreservation; Deferoxamine; Ischemia; Kidney Cortex; Malondialdehyde; Rabbits; Tissue Preservation | 1997 |
Increased ascorbate radical formation and ascorbate depletion in plasma from women with preeclampsia: implications for oxidative stress.
Topics: Adult; Ascorbic Acid; Chromatography, High Pressure Liquid; Deferoxamine; Electron Spin Resonance Spectroscopy; Female; Free Radicals; Humans; Iron Chelating Agents; Oxidative Stress; Pre-Eclampsia; Pregnancy; Sulfhydryl Compounds; Vitamin E | 1997 |
[The effect of antioxidants on lipid metabolism in myocardium in experimental hyperthyroxinemic conditions].
Topics: Allopurinol; Animals; Antimetabolites; Antioxidants; Ascorbic Acid; Deferoxamine; Female; Heart; Hyperthyroxinemia; Injections, Intraperitoneal; Lipid Metabolism; Male; Myocardium; Phospholipids; Rats; Rats, Wistar; Siderophores; Thyroxine; Triglycerides | 1996 |
[The effect of some antioxidants on the response of selected lipid compounds in myocardium of rats].
Topics: Allopurinol; Animals; Antimetabolites; Antioxidants; Ascorbic Acid; Deferoxamine; Heart; Lipid Metabolism; Male; Myocardium; Rats; Rats, Wistar | 1996 |
Cardiac function during iron chelation therapy in adult non-thalassaemic patients with transfusional iron overload.
Topics: Adolescent; Adult; Aged; Aging; Antidotes; Ascorbic Acid; beta-Thalassemia; Chelating Agents; Coronary Angiography; Deferoxamine; Female; Humans; Injections, Subcutaneous; Iron Overload; Male; Middle Aged; Transfusion Reaction; Ventricular Function, Left | 1997 |
Active oxygen-mediated chromosomal 1-2 Mbp giant DNA fragmentation into internucleosomal DNA fragmentation in apoptosis of glioma cells induced by glutamate.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Ascorbic Acid; Catalase; Chromosomes; Deferoxamine; DNA Fragmentation; Free Radical Scavengers; Glioma; Glutamic Acid; Glutathione; Hydrogen Peroxide; Iron Chelating Agents; Oxidation-Reduction; Oxygen; Phenanthrolines; Rats; Tumor Cells, Cultured | 1998 |
Horseradish peroxidase-dependent oxidation of deuteroporphyrin IX into chlorins.
Topics: Ascorbic Acid; Catalase; Deferoxamine; Deuteroporphyrins; Edetic Acid; Glutathione; Horseradish Peroxidase; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Oxidation-Reduction; Oxygen; Photosensitizing Agents; Porphyrins; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds | 1998 |
In vivo dual effects of vitamin C on paraquat-induced lung damage: dependence on released metals from the damaged tissue.
Topics: Animals; Ascorbic Acid; Breath Tests; Deferoxamine; Ethane; Lipid Peroxidation; Lung; Lung Diseases; Male; Metals; Oxidation-Reduction; Paraquat; Proteins; Rats; Rats, Sprague-Dawley | 1998 |
Apparent role of hydroxyl radicals in oxidative brain injury induced by sodium nitroprusside.
Topics: Animals; Ascorbic Acid; Brain Injuries; Deferoxamine; Hydrogen Peroxide; Hydroxyl Radical; In Vitro Techniques; Iron; Lipid Peroxidation; Male; Nerve Degeneration; Nitric Oxide; Nitroprusside; Oxidative Stress; Oxyhemoglobins; Penicillamine; Rats; Rats, Sprague-Dawley | 1998 |
Chain-breaking antioxidants and ferriheme-bound drugs are synergistic inhibitors of erythrocyte membrane peroxidation.
Topics: Adult; Amidines; Antioxidants; Ascorbic Acid; Chloroquine; Deferoxamine; Drug Synergism; Erythrocyte Membrane; Fatty Acids; Female; Hemin; Humans; Linoleic Acid; Lipid Peroxidation; Male; Membrane Lipids; Oxidation-Reduction; Oxygen Consumption; Oxyhemoglobins; Probucol; Pyridines; Reperfusion Injury; Vitamin E | 1998 |
The effect of Gingko biloba extract (Egb 761) as a free radical scavenger on the survival of skin flaps in rats. A comparative study.
Topics: Animals; Antioxidants; Ascorbic Acid; Deferoxamine; Flavonoids; Free Radical Scavengers; Ginkgo biloba; Graft Survival; Plant Extracts; Rats; Rats, Sprague-Dawley; Surgical Flaps; Vitamin E | 1998 |
Spontaneous conversion of L-dehydroascorbic acid to L-ascorbic acid and L-erythroascorbic acid.
Topics: Ascorbic Acid; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Copper; Deferoxamine; Dehydroascorbic Acid; Electrochemistry; Gas Chromatography-Mass Spectrometry; Hydrogen-Ion Concentration; In Vitro Techniques; Iron; Models, Chemical; Molecular Structure; Oxidation-Reduction; Solutions; Spectrophotometry, Ultraviolet | 1998 |
Iron overload and antioxidant status in patients with beta-thalassemia major.
Topics: Antioxidants; Ascorbic Acid; beta-Thalassemia; Deferoxamine; Humans; Iron; Iron Chelating Agents; Liver; Transferrin; Vitamin A; Vitamin E | 1998 |
Studies by electron paramagnetic resonance of the importance of iron in the hydroxyl scavenging properties of ascorbic acid in plasma: effects of iron chelators.
Topics: Animals; Apoproteins; Ascorbic Acid; Deferoxamine; Edetic Acid; Electron Spin Resonance Spectroscopy; Ferrous Compounds; Free Radical Scavengers; Hydroxyl Radical; Iron; Iron Chelating Agents; Male; Rats; Rats, Wistar; Transferrin | 1998 |
Iron compounds catalyze the oxidation of 10-formyl-5,6,7,8 tetrahydrofolic acid to 10-formyl-7,8 dihydrofolic acid.
Topics: Animals; Apoproteins; Ascorbic Acid; Cattle; Citric Acid; Deferoxamine; Folic Acid; In Vitro Techniques; Iron Chelating Agents; Iron Compounds; Leucovorin; Oxidation-Reduction; Spectrophotometry, Ultraviolet; Transferrin | 1998 |
Acylated ascorbate stimulates collagen synthesis in cultured human foreskin fibroblasts at lower doses than does ascorbic acid.
Topics: Acylation; Antioxidants; Ascorbate Oxidase; Ascorbic Acid; Cells, Cultured; Collagen; Deferoxamine; DNA; Dose-Response Relationship, Drug; Fibroblasts; Humans; Hydroquinones; Oxidation-Reduction; Serum Albumin, Bovine; Skin; Time Factors | 1998 |
Effect of antioxidants on the kinetics of chain lipid peroxidation in liposomes.
Topics: Animals; Antioxidants; Ascorbic Acid; beta Carotene; Chick Embryo; Deferoxamine; Edetic Acid; Kinetics; Lipid Peroxidation; Liposomes; Luminescent Measurements; Rutin; Vitamin E | 1998 |
The role of reactive oxygen species in triggering proliferation and IL-2 secretion in T cells.
Topics: Antibodies, Monoclonal; Antigen-Presenting Cells; Antioxidants; Ascorbic Acid; Calcimycin; CD28 Antigens; Cell Division; Deferoxamine; Dimethyl Sulfoxide; Humans; In Vitro Techniques; Interleukin-2; Ionophores; Lymphocyte Activation; Reactive Oxygen Species; Second Messenger Systems; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1999 |
Cardioprotective effect of alpha-tocopherol, ascorbate, deferoxamine, and deferiprone: mitochondrial function in cultured, iron-loaded heart cells.
Topics: Animals; Animals, Newborn; Antioxidants; Ascorbic Acid; Cells, Cultured; Deferiprone; Deferoxamine; Heart; Intracellular Membranes; Iron; Iron Chelating Agents; Mitochondria, Heart; Myocardium; NAD; Pyridones; Rats; Succinate Dehydrogenase; Vitamin E | 1999 |
Effect of deferoxamine on post-hypoxic-ischemic reperfusion injury of the newborn lamb heart.
Topics: Animals; Animals, Newborn; Ascorbic Acid; Chelating Agents; Deferoxamine; Dehydroascorbic Acid; Female; Heart; Hypoxia; Male; Malondialdehyde; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Oxidation-Reduction; Sheep | 1999 |
Prooxidant activity of ferrioxamine in isolated rat hepatocytes and linoleic acid micelles.
Topics: Animals; Ascorbic Acid; Deferoxamine; Ferric Compounds; Iron Chelating Agents; Linoleic Acid; Lipid Peroxidation; Liver; Male; Micelles; Oxidants; Rats; Rats, Wistar | 1999 |
Hemochromatosis and vitamin C.
Topics: Ascorbic Acid; Chelating Agents; Deferoxamine; Dietary Supplements; Drug Therapy, Combination; Hemochromatosis; Humans | 1999 |
2-Amino-5-chlorophenol toxicity in renal cortical slices from Fischer 344 rats: effect of antioxidants and sulfhydryl agents.
Topics: Animals; Antioxidants; Ascorbic Acid; Buthionine Sulfoximine; Chlorophenols; Deferoxamine; Dithiothreitol; Dose-Response Relationship, Drug; Free Radicals; Gluconeogenesis; Glutathione; In Vitro Techniques; Iron; Iron Chelating Agents; Kidney Cortex; Lipid Peroxidation; Male; Phenylenediamines; Pyruvic Acid; Rats; Rats, Inbred F344; Sulfhydryl Reagents | 1999 |
Kupffer cell-independent acute hepatocellular oxidative stress and decreased bile formation in post-cold-ischemic rat liver.
Topics: Animals; Antioxidants; Ascorbic Acid; Bile; Clodronic Acid; Cold Temperature; Deferoxamine; Fluoresceins; Hydrogen Peroxide; Kupffer Cells; Liver; Liver Transplantation; Male; Mitochondria, Liver; Oxidative Stress; Rats; Rats, Wistar; Reperfusion Injury; Taurocholic Acid; Vitamin E | 1999 |
Chromate-induced human erythrocytes haemoglobin oxidation and peroxidation: influence of vitamin E, vitamin C, salicylate, deferoxamine, and N-ethylmaleimide.
Topics: Ascorbic Acid; Chromates; Deferoxamine; Erythrocytes; Ethylmaleimide; Hemoglobins; Humans; Oxidation-Reduction; Salicylates; Thiobarbituric Acid Reactive Substances; Time Factors; Vitamin E | 2000 |
Interaction between 6-hydroxydopamine and transferrin: "Let my iron go".
Topics: Animals; Ascorbic Acid; Behavior, Animal; Deferoxamine; Electron Spin Resonance Spectroscopy; Ferric Compounds; Ferrozine; Free Radicals; Humans; Hydroxyl Radical; Injections, Intraperitoneal; Iron; Iron Chelating Agents; Male; Mice; Mice, Inbred A; Oxidopamine; Transferrin | 2000 |
Modulation of the phosphatase activity of calcineurin by oxidants and antioxidants in vitro.
Topics: Animals; Antioxidants; Ascorbic Acid; Brain; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Calcineurin; Cattle; Cell Line; Cyclic N-Oxides; Deferoxamine; Male; Mice; Oxidants; Paraquat; Peroxides; Pyrrolidines; Spin Labels; Sulfhydryl Compounds; Superoxides; Testis; Thiocarbamates; Thioctic Acid | 2000 |
Effect of cigarette smoke on salivary proteins and enzyme activities.
Topics: Acetylcysteine; Acid Phosphatase; Amylases; Antioxidants; Ascorbic Acid; Blood Proteins; Deferoxamine; Female; Glutathione; Humans; L-Lactate Dehydrogenase; Male; Nicotiana; Plants, Toxic; Saliva; Salivary Proteins and Peptides; Smoke; Smoking; Time Factors | 2000 |
Analysis of 3-morpholinosydnonimine and sodium nitroprusside effects on dopamine release in the striatum of freely moving rats: role of nitric oxide, iron and ascorbic acid.
Topics: Animals; Ascorbic Acid; Corpus Striatum; Deferoxamine; Dopamine; Iron; Male; Microdialysis; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Rats; Rats, Wistar | 2000 |
DNA-breaking versus DNA-protecting activity of four phenolic compounds in vitro.
Topics: Antioxidants; Ascorbic Acid; Caffeic Acids; Chelating Agents; Copper; Deferoxamine; DNA Damage; DNA, Superhelical; Electrophoresis, Agar Gel; Free Radical Scavengers; Gallic Acid; Gossypol; Hydroquinones; Iron; Mutagens; Oxidants; Oxidation-Reduction; Phenols | 2000 |
Electron paramagnetic resonance detection of free radicals in UV-irradiated human and mouse skin.
Topics: Animals; Antioxidants; Ascorbic Acid; Cyclic N-Oxides; Deferoxamine; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Mice; Mice, Hairless; Nitrogen Oxides; Oxidation-Reduction; Oxidative Stress; Pyridines; Skin; Spin Labels; Ultraviolet Rays | 2001 |
Oxidative insult in sheep red blood cells induced by T-butyl hydroperoxide: the roles of glutathione and glutathione peroxidase.
Topics: Animals; Antioxidants; Ascorbic Acid; Butylated Hydroxytoluene; Deferoxamine; Dithiothreitol; Erythrocytes; Genetic Engineering; Glutathione; Glutathione Peroxidase; Hemoglobins; Lipid Peroxidation; Membrane Proteins; Oxidative Stress; Sheep; tert-Butylhydroperoxide; Thiobarbituric Acid Reactive Substances; Vitamin E | 2001 |
Lucigenin chemiluminescence in human seminal plasma.
Topics: Acridines; Adult; Allopurinol; Antioxidants; Ascorbate Oxidase; Ascorbic Acid; Chromans; Deferoxamine; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Hydrogen-Ion Concentration; Infertility, Male; Luminescent Measurements; Male; Oxidants; Oxidation-Reduction; Oxygen; Oxygen Consumption; Reactive Oxygen Species; Semen; Semen Preservation; Superoxide Dismutase; Temperature | 2001 |
Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation.
Topics: Amino Acid Sequence; Ascorbic Acid; Cell Hypoxia; Deferoxamine; DNA-Binding Proteins; Ferrous Compounds; Humans; Hydroxylation; Hydroxyproline; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Ligases; Molecular Sequence Data; Nuclear Proteins; Oxygen; Point Mutation; Procollagen-Proline Dioxygenase; Protein Structure, Tertiary; Proteins; Recombinant Fusion Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Transcription Factors; Tumor Cells, Cultured; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases; Ubiquitins; Von Hippel-Lindau Tumor Suppressor Protein | 2001 |
3,4-Dichlorophenylhydroxylamine cytotoxicity in renal cortical slices from Fischer 344 rats.
Topics: Analysis of Variance; Aniline Compounds; Animals; Ascorbic Acid; Deferoxamine; Dithiothreitol; Dose-Response Relationship, Drug; Gluconeogenesis; Glutathione; Hydroxylamines; In Vitro Techniques; Kidney Cortex; Kidney Diseases; L-Lactate Dehydrogenase; Male; Pyruvic Acid; Rats; Rats, Inbred F344 | 2001 |
Effect of pre-loading oral glucosamine HCl/chondroitin sulfate/manganese ascorbate combination on experimental arthritis in rats.
Topics: Animals; Arthritis, Rheumatoid; Ascorbic Acid; Autoantibodies; Chondroitin Sulfates; Collagen; Deferoxamine; Dietary Supplements; Drug Therapy, Combination; Female; Glucosamine; Knee; Manganese; Organometallic Compounds; Rats; Severity of Illness Index | 2001 |
Physiological amounts of ascorbate potentiate phorbol ester-induced nuclear-binding of AP-1 transcription factor in cells of macrophagic lineage.
Topics: Animals; Ascorbic Acid; Cell Line; Cell Nucleus; Cycloheximide; Deferoxamine; Dimerization; Drug Synergism; Macrophages; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; Oxidation-Reduction; Protein Subunits; Proto-Oncogene Proteins c-jun; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2001 |
A study on the role of nitric oxide and iron in 3-morpholino-sydnonimine-induced increases in dopamine release in the striatum of freely moving rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcysteine; Animals; Ascorbic Acid; Corpus Striatum; Deferoxamine; Dialysis Solutions; Dopamine; Dose-Response Relationship, Drug; Free Radical Scavengers; Homovanillic Acid; Iron; Male; Metalloporphyrins; Molsidomine; Movement; Nitric Oxide; Nitric Oxide Donors; Rats; Rats, Wistar; Uric Acid | 2001 |
Individual and synergistic antioxidative actions of melatonin: studies with vitamin E, vitamin C, glutathione and desferrioxamine (desferoxamine) in rat liver homogenates.
Topics: Animals; Antioxidants; Ascorbic Acid; Cell Membrane; Deferoxamine; Dose-Response Relationship, Drug; Drug Synergism; Glutathione; In Vitro Techniques; Lipid Peroxidation; Lipids; Malondialdehyde; Melatonin; Proteins; Rats; Vitamin E | 2001 |
Impaired endothelial regulation of ventricular relaxation in cardiac hypertrophy: role of reactive oxygen species and NADPH oxidase.
Topics: Animals; Antioxidants; Arginine; Ascorbic Acid; Biopterins; Deferoxamine; Drug Synergism; Endothelium, Vascular; Free Radical Scavengers; Glutathione; Guinea Pigs; Heart Ventricles; Hypertrophy, Left Ventricular; In Vitro Techniques; Male; Malondialdehyde; Metalloporphyrins; Myocardial Contraction; NADPH Oxidases; Oxidation-Reduction; Reactive Oxygen Species; Substance P | 2001 |
Evidence that hydroxyl radicals mediate auxin-induced extension growth.
Topics: 2,4-Dichlorophenoxyacetic Acid; Ascorbic Acid; Benzoates; Catecholamines; Cell Wall; Cotyledon; Deferoxamine; Hydrogen Peroxide; Hydroxyl Radical; Imidazolines; Indoleacetic Acids; NAD; NADP; Naphthaleneacetic Acids; Organometallic Compounds; Oxygen; Reactive Oxygen Species; Superoxide Dismutase; Superoxides; Zea mays | 2002 |
Prevention of the areca nut extract-induced unscheduled DNA synthesis of gingival keratinocytes by vitamin C and thiol compounds.
Topics: Antioxidants; Areca; Ascorbic Acid; Cells, Cultured; Chelating Agents; Deferoxamine; DNA; Gingiva; Humans; Keratinocytes; Mouth Neoplasms; Plant Extracts; Sulfhydryl Compounds | 2002 |
Dihydroisotanshinone I protects against menadione-induced toxicity in a primary culture of rat hepatocytes.
Topics: Animals; Antioxidants; Ascorbic Acid; Cell Survival; Cells, Cultured; Deferoxamine; Free Radical Scavengers; Glutathione; Hepatocytes; Lipid Peroxidation; Malondialdehyde; NAD(P)H Dehydrogenase (Quinone); Phenanthrenes; Phytotherapy; Plant Extracts; Plant Roots; Rats; Rats, Sprague-Dawley; Salvia; Superoxides; Vitamin K 3 | 2002 |
Examination of the antiproliferative activity of iron chelators: multiple cellular targets and the different mechanism of action of triapine compared with desferrioxamine and the potent pyridoxal isonicotinoyl hydrazone analogue 311.
Topics: Animals; Ascorbic Acid; Blotting, Northern; Blotting, Western; Cell Division; Chelating Agents; Deferoxamine; DNA; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Free Radicals; Glutathione; Humans; Iron; Iron Chelating Agents; Isoniazid; Models, Chemical; Oxidation-Reduction; Oxygen; Plasmids; Protein Binding; Pyridines; Rats; Thiosemicarbazones; Time Factors; Tumor Cells, Cultured | 2003 |
Oxalate deposition on asbestos bodies.
Topics: Asbestos, Crocidolite; Asbestosis; Ascorbic Acid; Calcium Oxalate; Crystallization; Crystallography, X-Ray; Deferoxamine; Fatal Outcome; Humans; Hydrogen Peroxide; Iron; Iron Chelating Agents; Lung; Male; Middle Aged; Oxidation-Reduction; Thiourea | 2003 |
The effects of desferrioxamine on cisplatin-induced lipid peroxidation and the activities of antioxidant enzymes in rat kidneys.
Topics: Animals; Antineoplastic Agents; Antioxidants; Ascorbic Acid; Catalase; Cisplatin; Deferoxamine; Female; Glutathione Reductase; Iron Chelating Agents; Kidney; Lipid Peroxidation; Male; Rats; Rats, Wistar; Superoxide Dismutase; Vitamin E | 2004 |
Molecular shuttle chelation: the use of ascorbate, desferrioxamine and Feralex-G in combination to remove nuclear bound aluminum.
Topics: Aged; Aluminum; Ascorbic Acid; Binding Sites; Brain Chemistry; Cell Nucleus; Chelating Agents; Chelation Therapy; Deferoxamine; Diffusion; Drug Synergism; Humans; Molecular Structure; Monosaccharides; Neurodegenerative Diseases; Neuroglia; Neurons; Pyridones; Subcellular Fractions; Terminology as Topic | 2004 |
Modulation of iron on mitochondrial aconitase expression in human prostatic carcinoma cells.
Topics: Aconitate Hydratase; Adenosine Triphosphate; Ascorbic Acid; Base Sequence; Cell Line, Tumor; Cell Proliferation; Chelating Agents; Citrates; Deferoxamine; Dose-Response Relationship, Drug; Ferric Compounds; Gene Expression Regulation, Neoplastic; Genes, Reporter; Genetic Vectors; Hemin; Humans; Immunoblotting; Iron; Male; Mitochondria; Molecular Sequence Data; Mutagenesis, Site-Directed; Prostatic Neoplasms; Protein Biosynthesis; Quaternary Ammonium Compounds; Signal Transduction; Transcription, Genetic; Up-Regulation | 2004 |
Combination treatment of vitamin C and desferrioxamine suppresses glomerular superoxide and prostaglandin E production in diabetic rats.
Topics: Animals; Ascorbic Acid; Deferoxamine; Depression, Chemical; Diabetes Mellitus, Experimental; Dinoprostone; Iron Chelating Agents; Kidney Glomerulus; Luminescent Measurements; Male; Rats; Rats, Sprague-Dawley; Superoxides | 2005 |
Ternary complex formation facilitates a redox mechanism for iron release from a siderophore.
Topics: Algorithms; Ascorbic Acid; Deferoxamine; Ferric Compounds; Glutathione; Iron; Iron Chelating Agents; Kinetics; Models, Chemical; Molecular Structure; Oxidation-Reduction; Phenanthrolines; Siderophores; Thermodynamics | 2006 |
Comparative study of the protective effect between deferoxamine and deferiprone on chronic iron overload induced cardiotoxicity in rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Ascorbic Acid; Deferiprone; Deferoxamine; Deoxyguanosine; Glutathione; Heart; Heart Diseases; Iron; Iron Chelating Agents; Iron Overload; Male; Myocardium; Pyridones; Rats; Thiobarbituric Acid Reactive Substances | 2006 |
Photobleaching of retinal pigment epithelium melanosomes reduces their ability to inhibit iron-induced peroxidation of lipids.
Topics: Albumins; Animals; Ascorbic Acid; Catalase; Cattle; Deferoxamine; Iron; Lipid Peroxidation; Lipid Peroxides; Melanins; Melanosomes; Oxygen Consumption; Photobleaching; Pigment Epithelium of Eye | 2007 |
Vitamin B12b increases the cytotoxicity of short-time exposure to ascorbic acid, inducing oxidative burst and iron-dependent DNA damage.
Topics: Antioxidants; Apoptosis; Ascorbic Acid; Cell Line, Tumor; Cell Survival; Deferoxamine; DNA Breaks, Single-Stranded; Humans; Hydrogen Peroxide; Hydroxocobalamin; Iron; Iron Chelating Agents; Oxidative Stress; Phenanthrolines; Respiratory Burst; Vitamins | 2007 |
Comparison of the kinetics of iron release from a marine (Trichodesmium erythraeum) Dps protein and mammalian ferritin in the presence and absence of ligands.
Topics: Animals; Ascorbic Acid; Bacterial Proteins; Cattle; Cyanobacteria; Deferoxamine; DNA-Binding Proteins; Ferritins; Horses; Iron; Kinetics; Ligands; Oxidation-Reduction; Spleen | 2007 |
Nonenzymatic formation of a novel hydroxylated sulfamethoxazole derivative in human liver microsomes: implications for bioanalysis of sulfamethoxazole metabolites.
Topics: Ascorbic Acid; Chromatography, High Pressure Liquid; Deferoxamine; Edetic Acid; Enzyme Inhibitors; Ferrous Compounds; Humans; Hydrogen Peroxide; Hydroxylation; Kinetics; Microsomes, Liver; Molecular Structure; NADP; Sulfamethoxazole; Tandem Mass Spectrometry; Triazoles | 2008 |
Cytotoxic effects of catechol to neuroblastoma N2a cells.
Topics: Animals; Antioxidants; Apoptosis; Ascorbic Acid; Catechols; Cell Line, Tumor; Cell Survival; Curcumin; Cysteine; Cytotoxins; Deferoxamine; Glutathione; Mice; Neuroblastoma; NF-kappa B; Reactive Oxygen Species; Sesquiterpenes; Superoxide Dismutase | 2008 |
Comparative mutagenic effects of structurally similar flavonoids quercetin and taxifolin on tester strains Salmonella typhimurium TA102 and Escherichia coli WP-2 uvrA.
Topics: Animals; Antioxidants; Ascorbic Acid; Catalase; Deferoxamine; Edetic Acid; Escherichia coli; Iron; Iron Chelating Agents; Liver Extracts; Microbial Sensitivity Tests; Mutagenesis; Mutagenicity Tests; Mutation; NADP; Quercetin; Rats; Salmonella typhimurium; Superoxide Dismutase | 2009 |
Effect of vitamin C, deferoxamine, quercetin and rutin against tert-butyl hydroperoxide oxidative damage in human erythrocytes.
Topics: Adult; Antioxidants; Ascorbic Acid; Deferoxamine; Erythrocytes; Female; Glucosephosphate Dehydrogenase; Glutathione; Heinz Bodies; Humans; Male; Methemoglobin; Middle Aged; Oxidative Stress; Quercetin; Rutin; tert-Butylhydroperoxide; Young Adult | 2009 |
Role of oxidative stress and MAPK signaling in reference moist smokeless tobacco-induced HOK-16B cell death.
Topics: Ascorbic Acid; Cell Death; Cell Line; Chromans; Deferoxamine; Dose-Response Relationship, Drug; Gene Expression Regulation; Humans; Keratinocytes; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Oxidative Stress; Time Factors; Tobacco, Smokeless | 2010 |
Chelation of intracellular iron enhances endothelial barrier function: a role for vitamin C?
Topics: 2,2'-Dipyridyl; Ascorbic Acid; Capillary Permeability; Cell Line; Colchicine; Collagen; Cytochalasin B; Cytoskeleton; Deferoxamine; Endothelial Cells; Fluorescent Dyes; Glutathione; Humans; Hydroxybenzoates; Inulin; Iron; Iron Chelating Agents; Organic Chemicals; Oxyquinoline | 2010 |
Metal ion-mobilizing additives for comprehensive detection of femtomole amounts of phosphopeptides by reversed phase LC-MS.
Topics: Adsorption; Aluminum; Amino Acid Sequence; Ascorbic Acid; Chromatography, Reverse-Phase; Coordination Complexes; Deferoxamine; Imidazoles; Iron; Molecular Sequence Data; Nanotechnology; Peptide Fragments; Phosphoproteins; Phosphorus; Reference Standards; Titanium | 2011 |
Ascorbate and deferoxamine administration after chlorine exposure decrease mortality and lung injury in mice.
Topics: Acute Lung Injury; Animals; Antioxidants; Ascorbic Acid; Chemical Warfare Agents; Chlorine; Chromatography, High Pressure Liquid; Deferoxamine; Inhalation Exposure; Injections, Intramuscular; Lipid Peroxidation; Male; Mice; Mice, Inbred C57BL; Pneumonia; Siderophores; Survival Rate | 2011 |
Novel cytochrome p450 bioactivation of a terminal phenyl acetylene group: formation of a one-carbon loss benzaldehyde and other oxidative products in the presence of N-acetyl cysteine or glutathione.
Topics: Acetylcysteine; Acetylene; Animals; Antioxidants; Ascorbic Acid; Benzaldehydes; Cattle; Chelating Agents; Cytochrome P-450 Enzyme System; Deferoxamine; Dogs; Glutathione; Humans; Male; Oxidation-Reduction; Rats; Rats, Sprague-Dawley | 2011 |
Effect of vitamin C and iron chelation on diesel exhaust particle and carbon black induced oxidative damage and cell adhesion molecule expression in human endothelial cells.
Topics: Ascorbic Acid; Cells, Cultured; Deferoxamine; DNA Damage; Endothelial Cells; Humans; Intercellular Adhesion Molecule-1; Iron Chelating Agents; Oxidative Stress; Particle Size; Reactive Oxygen Species; Soot; Vascular Cell Adhesion Molecule-1; Vehicle Emissions | 2011 |
Inhibition and disaggregation of α-synuclein oligomers by natural polyphenolic compounds.
Topics: Acetylcysteine; alpha-Synuclein; Antioxidants; Apigenin; Ascorbic Acid; Deferoxamine; Dose-Response Relationship, Drug; Flavanones; Flavonoids; Humans; Iron Chelating Agents; Microscopy, Confocal; Microscopy, Fluorescence; Molecular Structure; Mutation; Parkinson Disease; Phenols; Polyphenols; Protein Multimerization; Protein Structure, Quaternary; Recombinant Proteins; Spectrometry, Fluorescence; Structure-Activity Relationship | 2011 |
Ascorbic acid increases the activity and synthesis of tyrosinase in B16F10 cells through activation of p38 mitogen-activated protein kinase.
Topics: alpha-MSH; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ascorbic Acid; Deferoxamine; Disease Models, Animal; Enzyme Activation; Humans; Imidazoles; Intramolecular Oxidoreductases; MAP Kinase Signaling System; Melanins; Melanoma; Melanoma, Experimental; Mice; Microphthalmia-Associated Transcription Factor; Monophenol Monooxygenase; Oxidoreductases; Pyridines | 2011 |
Methemoglobin formation by triapine, di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone (Dp44mT), and other anticancer thiosemicarbazones: identification of novel thiosemicarbazones and therapeutics that prevent this effect.
Topics: Animals; Antineoplastic Agents; Ascorbic Acid; Cell Proliferation; Deferoxamine; Drug Interactions; Erythrocytes; Humans; Hypoxia; Iron; Iron Chelating Agents; Kinetics; Methemoglobin; Mice; Oxidation-Reduction; Oxyhemoglobins; Pyridines; Thiosemicarbazones | 2012 |
Methyl and ethyl ketone analogs of salicylaldehyde isonicotinoyl hydrazone: novel iron chelators with selective antiproliferative action.
Topics: Aldehydes; Antineoplastic Agents; Apoptosis; Ascorbic Acid; Caspases; Cell Cycle; Cell Line, Tumor; Deferoxamine; Drug Screening Assays, Antitumor; HL-60 Cells; Humans; Hydrazones; Iron Chelating Agents; Ketones; Membrane Potential, Mitochondrial; Oxidation-Reduction | 2012 |
Implication of glutathione in the in vitro antiplasmodial mechanism of action of ellagic acid.
Topics: Acetylcysteine; Animals; Antimalarials; Antioxidants; Ascorbic Acid; Buthionine Sulfoximine; Cells, Cultured; Deferoxamine; Drug Synergism; Ellagic Acid; Enzyme Inhibitors; Erythrocytes; Glutathione; Humans; Inhibitory Concentration 50; Mice; Oxidation-Reduction; Plasmodium falciparum; Plasmodium yoelii; Reactive Oxygen Species; Siderophores | 2012 |
Mechanism of the toxicity induced by natural humic acid on human vascular endothelial cells.
Topics: Ascorbic Acid; Caspases; Cell Survival; Deferoxamine; Glutathione; Human Umbilical Vein Endothelial Cells; Humans; Humic Substances; Hydrogen Peroxide; Indonesia; Iron; Iron Chelating Agents; L-Lactate Dehydrogenase; Oxidative Stress; Rivers; Soil Pollutants; Vitamins; Water Pollutants | 2014 |
Generation of ferric iron links oxidative stress to α-synuclein oligomer formation.
Topics: alpha-Synuclein; Ascorbic Acid; Deferoxamine; Dose-Response Relationship, Drug; Ferric Compounds; Humans; Hydrogen Peroxide; Microscopy, Confocal; Models, Biological; Oxidation-Reduction; Siderophores | 2011 |
Mefloquine in combination with hemin causes severe damage to adult Schistosoma japonicum in vitro.
Topics: 2,2'-Dipyridyl; Animals; Anthelmintics; Ascorbic Acid; Cysteine; Deferiprone; Deferoxamine; Drug Synergism; Drug Therapy, Combination; Ferric Compounds; Ferrous Compounds; Glutathione; Hemin; Inhibitory Concentration 50; Iron Chelating Agents; Mefloquine; Protoporphyrins; Pyridones; Schistosoma japonicum | 2014 |
Iron and aluminum in Alzheimer's disease.
Topics: Aged; Aluminum; Alzheimer Disease; Antioxidants; Ascorbic Acid; Chelation Therapy; Deferoxamine; Epilepsy; Fatal Outcome; Female; Humans; Iron; Siderophores | 2013 |
Genotoxic effect of ethacrynic acid and impact of antioxidants.
Topics: Antioxidants; Ascorbic Acid; Buthionine Sulfoximine; Chromans; Cyclin-Dependent Kinase Inhibitor p21; Deferoxamine; DNA Damage; Ethacrynic Acid; Glutathione; HCT116 Cells; Heme Oxygenase-1; Humans; Mutagens; NF-E2-Related Factor 2; Reactive Oxygen Species; RNA, Messenger; Transcription Factor CHOP; Tumor Suppressor Protein p53 | 2015 |
Synergistic effect of reductive and ligand-promoted dissolution of goethite.
Topics: Acetates; Adsorption; Ascorbic Acid; Deferoxamine; Ethylenediamines; Hydrogen-Ion Concentration; Iron; Iron Compounds; Kinetics; Ligands; Linear Models; Minerals; Oxidation-Reduction; Reducing Agents; Solubility; Temperature | 2015 |
Hypoxia induces NO-dependent release of heparan sulfate in fibroblasts from the Alzheimer mouse Tg2576 by activation of nitrite reduction.
Topics: Alzheimer Disease; Animals; Antibodies, Monoclonal; Ascorbic Acid; Cell Hypoxia; Deferoxamine; Disease Models, Animal; Enzyme Inhibitors; Fibroblasts; Glypicans; Heparitin Sulfate; Humans; Iron Chelating Agents; Mannose; Mice; Mice, Transgenic; Microscopy, Fluorescence; Nitric Oxide; Nitrite Reductases; Nitrites; Oxidation-Reduction; Oxygen; p38 Mitogen-Activated Protein Kinases; Primary Cell Culture | 2016 |
Biphasic effects of l-ascorbate on the tumoricidal activity of non-thermal plasma against malignant mesothelioma cells.
Topics: Antineoplastic Agents; Antioxidants; Apoptosis; Ascorbic Acid; Autophagy; Cell Line, Tumor; Cell Survival; Deferoxamine; Dose-Response Relationship, Drug; Humans; Lung Neoplasms; Mesothelioma; Mesothelioma, Malignant; Microscopy, Fluorescence; Oxidative Stress; Plasma Gases; Reactive Oxygen Species; Temperature | 2016 |
Analogues of desferrioxamine B designed to attenuate iron-mediated neurodegeneration: synthesis, characterisation and activity in the MPTP-mouse model of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antioxidants; Ascorbic Acid; Benzothiazoles; Blood Proteins; Deferoxamine; Disease Models, Animal; Iron; Iron Chelating Agents; Mice; Nerve Degeneration; Neurons; Parkinson Disease; Sulfonic Acids | 2017 |
Augmentation of intracellular iron using iron sucrose enhances the toxicity of pharmacological ascorbate in colon cancer cells.
Topics: Ascorbic Acid; Catalase; Cell Survival; Colonic Neoplasms; Deferoxamine; Ferric Compounds; Ferric Oxide, Saccharated; Glucaric Acid; HCT116 Cells; HT29 Cells; Humans; Hydrogen Peroxide; Iron; Iron Chelating Agents; Oxidative Stress | 2018 |
A carbon dot-based fluorescent nanoprobe for the associated detection of iron ions and the determination of the fluctuation of ascorbic acid induced by hypoxia in cells and in vivo.
Topics: Animals; Ascorbic Acid; Carbon; Cell Hypoxia; Deferoxamine; Fluorescent Dyes; Hep G2 Cells; Humans; Hypoxia; Iron; Ischemia; Limit of Detection; Liver; Mice, Inbred BALB C; Microscopy, Confocal; Microscopy, Fluorescence; Oxidative Stress; Quantum Dots; Zebrafish | 2019 |
The application of pharmaceutical quality by design concepts to evaluate the antioxidant and antimicrobial properties of a preservative system including desferrioxamine.
Topics: Anti-Infective Agents; Antioxidants; Ascorbic Acid; Aspergillus; Candida albicans; Deferoxamine; Edetic Acid; Escherichia coli; Microbial Sensitivity Tests; Models, Theoretical; Parabens; Preservatives, Pharmaceutical; Pseudomonas aeruginosa; Staphylococcus aureus; Sulfites | 2020 |
Proteomic Investigation of the Antibacterial Mechanism of Cefiderocol against Escherichia coli.
Topics: Acetylcysteine; Anti-Bacterial Agents; Antioxidants; Ascorbic Acid; Cefepime; Cefiderocol; Ceftazidime; Cephalosporins; Deferoxamine; Escherichia coli; Flavin-Adenine Dinucleotide; Hydrogen Peroxide; Iron; NAD; NADP; Proteomics; Quinones; Reactive Oxygen Species; Siderophores; Sulfur | 2022 |