deferoxamine has been researched along with acetaminophen in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (39.13) | 18.7374 |
| 1990's | 7 (30.43) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (21.74) | 24.3611 |
| 2020's | 2 (8.70) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Dybing, E | 1 |
| Kayano, K; Kubota, M; Mori, K; Okita, K; Sakaida, I; Takenaka, K; Yasunaga, M | 1 |
| Farber, JL; Harman, AW; Kyle, ME; Serroni, A | 1 |
| Farber, JL; Kyle, ME; Sakaida, I; Serroni, A | 1 |
| Tsokos-Kuhn, JO | 1 |
| Lemoine, R; Sause, C; Siegers, CP; Younes, M | 1 |
| Farber, JL; Kyle, ME; Miccadei, S; Nakae, D | 1 |
| Cotgreave, IA; Harvison, PJ; Moldéus, P; Nelson, SD; Porubek, DJ; Rundgren, M | 1 |
| Farber, JL; Kyle, ME; Nakae, D; Serroni, A | 1 |
| Farber, JL; Nakae, D; Oakes, JW | 1 |
| Casini, A; Farber, JL; Gerson, RJ; Gilfor, D; Serroni, A | 1 |
| Siegers, CP; Younes, M | 1 |
| Kayano, K; Matsumura, Y; Nagatomi, A; Okita, K; Sakaida, I; Wasaki, S | 1 |
| Harada, T; Hiraishi, H; Ito, Y; Ivey, KJ; Ogonuki, H; Razandi, M; Suzuki, Y; Terano, A | 1 |
| Adamson, GM; Harman, AW | 1 |
| Bucci, TJ; Hinson, JA; Kusewitt, DF; Pumford, NR; Schnellmann, JG | 1 |
| Carvalho-Silva, M; Daufenbach, JF; Ferreira, GK; Gonçalves, CL; Jeremias, GC; Jeremias, IC; Panatto, JP; Ramos, AC; Rezin, GT; Rochi, N; Scaini, G; Streck, EL | 1 |
| Beeson, CC; Hu, J; Jaeschke, H; Kholmukhamedov, A; Lemasters, JJ; Lindsey, CC | 1 |
| Hara, S; Ito, J; Kamata, R; Karasawa, T; Kimura, H; Komada, T; Kuwata, H; Mizuta, K; Nakagawa, K; Sakuma, Y; Sampilvanjil, A; Sata, N; Takahashi, M; Watanabe, S; Yamada, N | 1 |
| Adelusi, OB; Jaeschke, H; Lemasters, JJ; Ramachandran, A | 1 |
1 review(s) available for deferoxamine and acetaminophen
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
22 other study(ies) available for deferoxamine and acetaminophen
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Methyldopa binding to cells in culture.
Topics: Acetaminophen; Allopurinol; Animals; Ascorbic Acid; Carcinoma, Hepatocellular; Cells, Cultured; Deferoxamine; Dimethylnitrosamine; Edetic Acid; Furosemide; Glutathione; Liver Neoplasms; Maleates; Methyldopa; Neoplasms, Experimental; Protein Binding; Rats; Superoxide Dismutase; Time Factors; Xanthines | 1977 |
Protective effect of deferoxamine for acetaminophen induced liver injury.
Topics: Acetaminophen; Animals; Deferoxamine; Dose-Response Relationship, Drug; Liver; Male; Necrosis; Rats; Rats, Inbred Strains | 1992 |
The killing of cultured hepatocytes by N-acetyl-p-benzoquinone imine (NAPQI) as a model of the cytotoxicity of acetaminophen.
Topics: Acetaminophen; Acidosis; Adenosine Triphosphate; Animals; Benzoflavones; Benzoquinones; beta-Naphthoflavone; Carmustine; Cell Survival; Cells, Cultured; Deferoxamine; Glutathione; Glutathione Reductase; Imines; In Vitro Techniques; Liver; Models, Biological; Monensin; Oxidation-Reduction; Phenylenediamines; Rats | 1991 |
Metabolism of acetaminophen by cultured rat hepatocytes. Depletion of protein thiol groups without any loss of viability.
Topics: Acetaminophen; Animals; Carmustine; Cells, Cultured; Deferoxamine; Glutathione; Glutathione Disulfide; Liver; Male; Phenylenediamines; Proteins; Rats; Rats, Inbred Strains; Sulfhydryl Compounds | 1990 |
Evidence in vivo for elevation of intracellular free Ca2+ in the liver after diquat, acetaminophen, and CCl4.
Topics: Acetaminophen; Animals; Calcium; Carbon Tetrachloride; Deferoxamine; Diquat; Lipid Peroxidation; Liver; Male; Phosphorylase a; Pyridinium Compounds; Rats; Rats, Inbred F344; Rats, Inbred Strains | 1989 |
Effect of deferrioxamine and diethyldithiocarbamate on paracetamol-induced hepato- and nephrotoxicity. The role of lipid peroxidation.
Topics: Acetaminophen; Animals; Creatinine; Deferoxamine; Ditiocarb; Ethane; Glutathione; Kidney; Lipid Peroxides; Liver; Male; Malondialdehyde; Mice | 1988 |
Superoxide dismutase and catalase protect cultured hepatocytes from the cytotoxicity of acetaminophen.
Topics: Acetaminophen; Animals; Benzoflavones; beta-Naphthoflavone; Carmustine; Catalase; Chlorides; Deferoxamine; Drug Resistance; Ferric Compounds; Ferrous Compounds; Free Radicals; Liver; Male; Mannitol; Methylcholanthrene; Mixed Function Oxygenases; Rats; Rats, Inbred Strains; Superoxide Dismutase | 1987 |
Comparative cytotoxic effects of N-acetyl-p-benzoquinone imine and two dimethylated analogues.
Topics: Acetaminophen; Animals; Benzoquinones; Carmustine; Cell Survival; Chemical Phenomena; Chemistry; Deferoxamine; Dithiothreitol; Dose-Response Relationship, Drug; Glutathione; Imines; Lipid Peroxides; Liver; Oxidation-Reduction; Oxygen; Rats; Structure-Activity Relationship | 1988 |
1,3-(2-Chloroethyl)-1-nitrosourea potentiates the toxicity of acetaminophen both in the phenobarbital-induced rat and in hepatocytes cultured from such animals.
Topics: Acetaminophen; Acetone; Carmustine; Cell Survival; Deferoxamine; Drug Synergism; Enzyme Induction; Glutathione; Liver; Male; Maleates; Methylcholanthrene; Phenobarbital; Phenylenediamines | 1988 |
Potentiation in the intact rat of the hepatotoxicity of acetaminophen by 1,3-bis(2-chloroethyl)-1-nitrosourea.
Topics: Acetaminophen; Animals; Carmustine; Chemical and Drug Induced Liver Injury; Deferoxamine; Drug Synergism; Glutathione Reductase; Male; Methylcholanthrene; Rats; Rats, Inbred Strains | 1988 |
Oxygen-mediated cell injury in the killing of cultured hepatocytes by acetaminophen.
Topics: Acetaminophen; Animals; Antioxidants; Biotransformation; Cell Survival; Deferoxamine; Glutathione; In Vitro Techniques; Liver; Male; Oxidation-Reduction; Oxygen; Rats; Rats, Inbred Strains | 1985 |
The role of iron in the paracetamol- and CCl4-induced lipid peroxidation and hepatotoxicity.
Topics: Acetaminophen; Animals; Breath Tests; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Deferoxamine; Enzyme Induction; Ethane; Iron; Lipid Peroxides; Male; Mice; Phenobarbital; Rats; Rats, Inbred Strains | 1985 |
Protection against acetaminophen-induced liver injury in vivo by an iron chelator, deferoxamine.
Topics: Acetaminophen; Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Deferoxamine; Glutathione; Iron Chelating Agents; Liver; Male; Rats; Rats, Wistar | 1995 |
Role of iron and glutathione redox cycle in acetaminophen-induced cytotoxicity to cultured rat hepatocytes.
Topics: Acetaminophen; Amitrole; Animals; Carmustine; Catalase; Cells, Cultured; Chromium Radioisotopes; Cytochrome P-450 Enzyme System; Deferoxamine; Glutathione; Glutathione Reductase; Iron; L-Lactate Dehydrogenase; Liver; Male; Maleates; Methylcholanthrene; Oxidation-Reduction; Phenanthrolines; Rats; Rats, Sprague-Dawley | 1994 |
Oxidative stress in cultured hepatocytes exposed to acetaminophen.
Topics: Acetaminophen; Animals; Carmustine; Cells, Cultured; Deferoxamine; Glutathione; Glutathione Disulfide; Liver; Male; Mice | 1993 |
Deferoxamine delays the development of the hepatotoxicity of acetaminophen in mice.
Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Animals; Chelating Agents; Deferoxamine; Dose-Response Relationship, Drug; Kupffer Cells; Liver; Male; Mice | 1999 |
Inhibition of mitochondrial respiratory chain in the brain of rats after hepatic failure induced by acetaminophen.
Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Animals; Antioxidants; Brain; Deferoxamine; Down-Regulation; Drug Evaluation, Preclinical; Electron Transport; Liver Failure; Male; Mitochondria; Rats; Rats, Wistar; Taurine | 2011 |
Translocation of iron from lysosomes to mitochondria during acetaminophen-induced hepatocellular injury: Protection by starch-desferal and minocycline.
Topics: Acetaminophen; Animals; Cell Survival; Cells, Cultured; Chemical and Drug Induced Liver Injury; Deferoxamine; Drug Evaluation, Preclinical; Hepatocytes; Iron; Iron Chelating Agents; Lysosomes; Male; Mice, Inbred C57BL; Minocycline; Mitochondria; Oxidative Stress; Reactive Oxygen Species; Ruthenium Compounds; Starch | 2016 |
Ferroptosis driven by radical oxidation of n-6 polyunsaturated fatty acids mediates acetaminophen-induced acute liver failure.
Topics: Acetaminophen; alpha-Tocopherol; Animals; Antioxidants; Coenzyme A Ligases; Cyclohexylamines; Cyclooxygenase 2; Deferoxamine; Disease Models, Animal; Fatty Acids, Omega-6; Ferroptosis; Hepatocytes; Humans; Iron Chelating Agents; Lipid Peroxidation; Liver; Liver Failure, Acute; Mice, Inbred C57BL; Mice, Knockout; Oxidation-Reduction; Phenylenediamines | 2020 |
The role of Iron in lipid peroxidation and protein nitration during acetaminophen-induced liver injury in mice.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Deferoxamine; Hepatocytes; Iron; Lipid Peroxidation; Liver; Male; Mice; Mice, Inbred C57BL; Minocycline; Mitochondria, Liver; Oxidative Stress; Peroxynitrous Acid | 2022 |