deferiprone and transferrin

deferiprone has been researched along with transferrin in 36 studies

Research

Studies (36)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (5.56)	18.7374
1990's	12 (33.33)	18.2507
2000's	12 (33.33)	29.6817
2010's	10 (27.78)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
al-Refaie, FN; Hoffbrand, AV; Kontoghiorghes, GJ; Wickens, DG; Wonke, B	1
Kline, MA; Orvig, C	1
Bartlett, AN; Goddard, JG; Kontoghiorghes, GJ; Sheppard, L	1
Charalambous, J; Hoffbrand, AV; Kontoghiorghes, GJ; Pippard, MJ; Sheppard, L; Tikerpae, J	1
Evans, RW; Kontoghiorghes, GJ	1
Olivieri, NF; Parkes, JG; Randell, EW; Templeton, DM	1
al-Refaie, FN; De Silva, CE; Hoffbrand, AV; Wonke, B	1
Boelaert, J; Papavassiliou, P; Soteriadou, K; Voyiatzaki, C	1
Boelaert, JR; Crichton, RR; de Locht, M; Schneider, YJ; Van Cutsem, J	1
Arnaud, J; Bolder, U; Brissot, P; Hofmann, AF; Schteingart, CD	1
AL-Refaie, F; Cochrane, J; Davis, B; Hoffbrand, AV; Jackson, BF; Prescott, E; Siritanakatkul, N; Wonke, B	1
Harris, WR; Li, Y	1
Brown, T; Harris, WR; Li, Y; MacGillivray, RT; Maxwell, A	1
Bartfay, WJ; Lehotay, DC; Liu, PP; Sher, GD	1
Raymond, KN; Stintzi, A; Turcot, I; Xu, J	1
Abramov, A; Breuer, W; Cabantchik, ZI; Ermers, MJ; Hershko, C; Pootrakul, P	1
Weinberg, ED	1
Breuer, W; Cabantchik, ZI; Hershko, C; Pootrakul, P; Sametband, M; Sirankapracha, P	1
Barker, IK; Conlon, PD; Jacobs, RM; Mehren, KG; Whiteside, DP	1
Kwok, JC; Richardson, DR; Wong, CS	1
Eracleous, E; Evans, RW; Kolnagou, A; Kontoghiorghes, GJ	1
Kontoghiorghes, GJ	1
Fucharoen, S; Phisalaphong, C; Porter, JB; Srichairatanakool, S; Thephinlap, C	1
Fibach, E; Prus, E	1
Costa Pessoa, J; Enyedy, EA; González, CS; Hollender, D; Jakusch, T; Kiss, T; Montes-Bayón, M; Sanz-Medel, A; Tomaz, I	1
Kim, CM; Shin, SH	1
Eccleston, J; Evans, P; Hider, RC; Kayyali, R; Porter, JB	1
Hershko, C	1
Chantharaksri, U; Fucharoen, S; Jirasomprasert, T; Jittangprasert, P; Limenta, LM; Morales, NP; Wilairat, P; Yamanont, P	1
Breuer, W; Cabantchik, ZI; Mitterstiller, AM; Sohn, YS; Weiss, G	1
Harris, WR; Sharma, R	1
Baccan, MM; Chiarelli-Neto, O; Espósito, BP; Pereira, RM	1
Kummel, AC; Liberman, A; Pohaku Mitchell, KK; Trogler, WC	1
Chen, Y; Hu, W; Sun, XG; Sun, Z; Tang, Q; Wang, G; Wang, L; Xue, F; Yin, Y	1
Fraňková, S; Jirsa, M; Kautzner, J; Kautznerová, D; Křížová, B; Kubánek, M; Malušková, J; Melenovský, V; Tauchenová, L; Tintěra, J	1
Boesen, EI; Bonnemaison, ML; Brusnahan, SK; Fan, W; Garrison, JC; Marks, ES; Zhang, W	1

Reviews

2 review(s) available for deferiprone and transferrin

Article	Year
Iron chelation in chemotherapy. Advances in applied microbiology, 2003, Volume: 52 Topics: Animals; Deferiprone; Deferoxamine; Humans; Iron Chelating Agents; Iron Overload; Lactoferrin; Pyridones; Transferrin	2003
Iron mobilization from transferrin and non-transferrin-bound-iron by deferiprone. Implications in the treatment of thalassemia, anemia of chronic disease, cancer and other conditions. Hemoglobin, 2006, Volume: 30, Issue:2 Topics: Anemia; Chelation Therapy; Chronic Disease; Combined Modality Therapy; Deferiprone; Humans; Iron; Iron Chelating Agents; Iron Overload; Models, Biological; Mononuclear Phagocyte System; Neoplasms; Protein Binding; Pyridones; Thalassemia; Transferrin; Transfusion Reaction	2006

Article

Year

Iron chelation in chemotherapy.

Advances in applied microbiology, 2003, Volume: 52

Topics: Animals; Deferiprone; Deferoxamine; Humans; Iron Chelating Agents; Iron Overload; Lactoferrin; Pyridones; Transferrin

2003

Iron mobilization from transferrin and non-transferrin-bound-iron by deferiprone. Implications in the treatment of thalassemia, anemia of chronic disease, cancer and other conditions.

Hemoglobin, 2006, Volume: 30, Issue:2

Topics: Anemia; Chelation Therapy; Chronic Disease; Combined Modality Therapy; Deferiprone; Humans; Iron; Iron Chelating Agents; Iron Overload; Models, Biological; Mononuclear Phagocyte System; Neoplasms; Protein Binding; Pyridones; Thalassemia; Transferrin; Transfusion Reaction

2006

Trials

2 trial(s) available for deferiprone and transferrin

Article	Year
Long-term trial of deferiprone in 51 transfusion-dependent iron overloaded patients. Blood, 1998, Jan-01, Volume: 91, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Anemia, Sickle Cell; beta-Thalassemia; Blood Transfusion; Chelating Agents; Chelation Therapy; Combined Modality Therapy; Deferiprone; Female; Hemoglobins; Humans; Iron; Iron Overload; Liver; Male; Middle Aged; Pyridones; Splenectomy; Transferrin; Transfusion Reaction	1998
Labile plasma iron (LPI) as an indicator of chelatable plasma redox activity in iron-overloaded beta-thalassemia/HbE patients treated with an oral chelator. Blood, 2004, Sep-01, Volume: 104, Issue:5 Topics: beta-Thalassemia; Biomarkers; Deferiprone; Erythrocyte Membrane; Follow-Up Studies; Hemoglobin E; Humans; Iron; Iron Chelating Agents; Iron Overload; Oxidation-Reduction; Predictive Value of Tests; Pyridones; Transferrin	2004

Article

Year

Long-term trial of deferiprone in 51 transfusion-dependent iron overloaded patients.

Blood, 1998, Jan-01, Volume: 91, Issue:1

Topics: Adult; Aged; Aged, 80 and over; Anemia, Sickle Cell; beta-Thalassemia; Blood Transfusion; Chelating Agents; Chelation Therapy; Combined Modality Therapy; Deferiprone; Female; Hemoglobins; Humans; Iron; Iron Overload; Liver; Male; Middle Aged; Pyridones; Splenectomy; Transferrin; Transfusion Reaction

1998

Labile plasma iron (LPI) as an indicator of chelatable plasma redox activity in iron-overloaded beta-thalassemia/HbE patients treated with an oral chelator.

Blood, 2004, Sep-01, Volume: 104, Issue:5

Topics: beta-Thalassemia; Biomarkers; Deferiprone; Erythrocyte Membrane; Follow-Up Studies; Hemoglobin E; Humans; Iron; Iron Chelating Agents; Iron Overload; Oxidation-Reduction; Predictive Value of Tests; Pyridones; Transferrin

2004

Other Studies

32 other study(ies) available for deferiprone and transferrin

Article	Year
Serum non-transferrin-bound iron in beta-thalassaemia major patients treated with desferrioxamine and L1. British journal of haematology, 1992, Volume: 82, Issue:2 Topics: Adolescent; Adult; beta-Thalassemia; Child; Child, Preschool; Deferiprone; Deferoxamine; Ferritins; Humans; Iron; Iron Chelating Agents; Patient Compliance; Pyridones; Transferrin	1992
Complexation of iron with the orally active decorporation drug L1 (3-hydroxy-1,2-dimethyl-4-pyridinone). Clinical chemistry, 1992, Volume: 38, Issue:4 Topics: Chelating Agents; Computer Simulation; Deferiprone; Deferoxamine; Humans; Hydrogen-Ion Concentration; Iron; Potentiometry; Pyridones; Transferrin	1992
Pharmacokinetic studies in humans with the oral iron chelator 1,2-dimethyl-3-hydroxypyrid-4-one. Clinical pharmacology and therapeutics, 1990, Volume: 48, Issue:3 Topics: Adult; Aged; Deferiprone; Female; Glucuronidase; Half-Life; Humans; Iron; Iron Chelating Agents; Male; Middle Aged; Pyridones; Transferrin	1990
Iron chelation studies using desferrioxamine and the potential oral chelator, 1,2-dimethyl-3-hydroxypyrid-4-one, in normal and iron loaded rats. Journal of clinical pathology, 1987, Volume: 40, Issue:4 Topics: Animals; Deferiprone; Deferoxamine; Female; Ferritins; Iron; Iron Chelating Agents; Iron Radioisotopes; Liver; Male; Pyridones; Rats; Rats, Inbred Strains; Time Factors; Transferrin	1987
Site specificity of iron removal from transferrin by alpha-ketohydroxypyridine chelators. FEBS letters, 1985, Sep-09, Volume: 189, Issue:1 Topics: Deferiprone; Electrophoresis, Polyacrylamide Gel; Humans; Iron; Mimosine; Pyridones; Time Factors; Transferrin	1985
Modulation by iron loading and chelation of the uptake of non-transferrin-bound iron by human liver cells. Biochimica et biophysica acta, 1995, Apr-13, Volume: 1243, Issue:3 Topics: Biological Transport; Carcinoma, Hepatocellular; Cell Death; Deferiprone; Deferoxamine; Diffusion; Ferric Compounds; Humans; Iron; Iron Chelating Agents; Iron Radioisotopes; Kinetics; Liver; Liver Neoplasms; Nitrilotriacetic Acid; Pyridones; Quaternary Ammonium Compounds; Transferrin; Tumor Cells, Cultured	1995
Changes in transferrin saturation after treatment with the oral iron chelator deferiprone in patients with iron overload. Journal of clinical pathology, 1995, Volume: 48, Issue:2 Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Chromatography, High Pressure Liquid; Deferiprone; Drug Administration Schedule; Electrophoresis, Polyacrylamide Gel; Female; Humans; Iron; Iron Chelating Agents; Male; Middle Aged; Pyridones; Transferrin	1995
Effect of iron chelation on the in-vitro growth of Leishmania promastigotes. The Journal of antimicrobial chemotherapy, 1995, Volume: 35, Issue:1 Topics: Animals; Deferiprone; Deferoxamine; DNA; Electrophoresis, Polyacrylamide Gel; Immunoblotting; Iodine Radioisotopes; Iron Chelating Agents; Leishmania infantum; Leishmania major; Pyridones; Transferrin	1995
Deferoxamine augments growth and pathogenicity of Rhizopus, while hydroxypyridinone chelators have no effect. Kidney international, 1994, Volume: 45, Issue:3 Topics: Animals; Deferiprone; Deferoxamine; Guinea Pigs; Iron; Iron Chelating Agents; Male; Mucormycosis; Pyridones; Rhizopus; Transferrin	1994
Intestinal absorption and enterohepatic cycling of biliary iron originating from plasma non-transferrin-bound iron in rats. Hepatology (Baltimore, Md.), 1997, Volume: 25, Issue:6 Topics: Animals; Bile; Deferiprone; Ferric Compounds; Injections, Intravenous; Intestinal Absorption; Intestinal Mucosa; Iron; Iron Chelating Agents; Iron Overload; Liver; Male; Pyridones; Rats; Rats, Sprague-Dawley; Reference Values; Transferrin	1997
Iron removal from monoferric human serum transferrins by 1, 2-dimethyl-3-hydroxypyridin-4-one, 1-hydroxypyridin-2-one and acetohydroxamic acid. Biochimica et biophysica acta, 1998, Sep-08, Volume: 1387, Issue:1-2 Topics: Allosteric Regulation; Animals; Binding Sites; Chlorides; Deferiprone; Humans; Hydroxamic Acids; Iron; Kinetics; Molecular Structure; Perchlorates; Protein Conformation; Pyridones; Spectrophotometry; Transferrin	1998
Kinetic studies on the removal of iron and aluminum from recombinant and site-directed mutant N-lobe half transferrins. Biochemistry, 1998, Oct-06, Volume: 37, Issue:40 Topics: Alanine; Aluminum; Animals; Arginine; Binding Sites; Cell Line; Cricetinae; Deferiprone; Humans; Iron; Kidney; Kinetics; Lysine; Macromolecular Substances; Mutagenesis, Site-Directed; Peptide Fragments; Pyridones; Recombinant Proteins; Transferrin	1998
Effect of transfusion on lipid peroxidation products in the plasma of thalassemic patients. Transfusion, 1999, Volume: 39, Issue:3 Topics: Aldehydes; beta-Thalassemia; Biomarkers; Chelation Therapy; Deferiprone; Deferoxamine; Erythrocyte Transfusion; Free Radicals; Humans; Iron; Iron Chelating Agents; Iron Overload; Lipid Peroxidation; Pilot Projects; Pyridones; Transferrin	1999
Fast biological iron chelators: kinetics of iron removal from human diferric transferrin by multidentate hydroxypyridonates. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2000, Volume: 5, Issue:5 Topics: Deferiprone; Gallium; Humans; Iron; Iron Chelating Agents; Kinetics; Ligands; Molecular Structure; Pyridones; Transferrin	2000
Desferrioxamine-chelatable iron, a component of serum non-transferrin-bound iron, used for assessing chelation therapy. Blood, 2001, Feb-01, Volume: 97, Issue:3 Topics: Adolescent; Adult; Apoproteins; Calibration; Chelation Therapy; Child; Deferiprone; Deferoxamine; Drug Therapy, Combination; Fluorescein; Humans; Iron; Iron Chelating Agents; Iron Overload; Kinetics; Microscopy, Fluorescence; Pyridones; Transferrin	2001
Clinical evaluation of the oral iron chelator deferiprone for the potential treatment of iron overload in bird species. Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2004, Volume: 35, Issue:1 Topics: Administration, Oral; Animals; Chickens; Columbidae; Deferiprone; Dose-Response Relationship, Drug; Female; Iron; Iron Chelating Agents; Iron Overload; Liver; Male; Poultry Diseases; Pyridones; Random Allocation; Species Specificity; Toxicity Tests; Transferrin; Treatment Outcome	2004
PCTH: a novel orally active chelator of the aroylhydrazone class that induces iron excretion from mice. Biochimica et biophysica acta, 2004, Dec-24, Volume: 1739, Issue:1 Topics: Administration, Oral; Animals; Blood Chemical Analysis; Body Weight; Cells, Cultured; Deferiprone; Eating; Feces; Iron; Iron Chelating Agents; Liver; Male; Mice; Mice, Inbred BALB C; Myocytes, Cardiac; Organ Size; Pyridones; Rats; Thiophenes; Transferrin	2004
Iron mobilisation from transferrin by deferiprone (L1). British journal of haematology, 2005, Volume: 129, Issue:1 Topics: Deferiprone; Humans; Iron; Iron Chelating Agents; Pyridones; Transferrin	2005
Curcumin contributes to in vitro removal of non-transferrin bound iron by deferiprone and desferrioxamine in thalassemic plasma. Medicinal chemistry (Shariqah (United Arab Emirates)), 2007, Volume: 3, Issue:5 Topics: Chromatography, High Pressure Liquid; Curcumin; Deferiprone; Deferoxamine; Humans; Iron; Iron Chelating Agents; Pyridones; Spectrophotometry, Ultraviolet; Thalassemia; Transferrin	2007
The labile iron pool in human erythroid cells. British journal of haematology, 2008, Volume: 142, Issue:2 Topics: Antigens, CD; beta-Thalassemia; Bone Marrow Cells; Cells, Cultured; Deferiprone; Erythroblasts; Erythrocytes; Erythropoiesis; Flow Cytometry; Fluoresceins; Fluorescent Dyes; Humans; Iron; Iron Chelating Agents; Pyridones; Reticulocytes; Transferrin	2008
Biospeciation of various antidiabetic V(IV)O compounds in serum. Dalton transactions (Cambridge, England : 2003), 2009, Apr-07, Issue:13 Topics: Apoproteins; Chromatography, High Pressure Liquid; Deferiprone; Humans; Hypoglycemic Agents; Mass Spectrometry; Molecular Structure; Organometallic Compounds; Pyridones; Pyrones; Serum Albumin; Thermodynamics; Time Factors; Transferrin; Ultrafiltration; Vanadium	2009
Effect of iron-chelator deferiprone on the in vitro growth of staphylococci. Journal of Korean medical science, 2009, Volume: 24, Issue:2 Topics: Deferiprone; Deferoxamine; Humans; Iron; Iron Chelating Agents; Iron Overload; Microbial Sensitivity Tests; Pyridones; Staphylococcus; Staphylococcus aureus; Transferrin	2009
Mechanisms for the shuttling of plasma non-transferrin-bound iron (NTBI) onto deferoxamine by deferiprone. Translational research : the journal of laboratory and clinical medicine, 2010, Volume: 156, Issue:2 Topics: Adult; Chromatography, High Pressure Liquid; Deferiprone; Deferoxamine; Female; Ferric Compounds; Humans; Iron; Iron Chelating Agents; Iron Overload; Kinetics; Male; Pyridones; Siderophores; Thalassemia; Transferrin; Transfusion Reaction	2010
Pathogenesis and management of iron toxicity in thalassemia. Annals of the New York Academy of Sciences, 2010, Volume: 1202 Topics: Benzoates; Deferasirox; Deferiprone; Deferoxamine; Homeostasis; Humans; Iron; Iron Chelating Agents; Iron Overload; Models, Molecular; Pyridones; Reactive Oxygen Species; Thalassemia; Transferrin; Transfusion Reaction; Triazoles	2010
Pharmacokinetics of deferiprone in patients with β-thalassaemia: impact of splenectomy and iron status. Clinical pharmacokinetics, 2011, Volume: 50, Issue:1 Topics: Administration, Oral; Adult; Area Under Curve; beta-Thalassemia; Deferiprone; Female; Ferritins; Hemoglobin E; Humans; Iron; Iron Chelating Agents; Iron Overload; Male; Pyridones; Splenectomy; Transferrin; Transfusion Reaction	2011
Rescuing iron-overloaded macrophages by conservative relocation of the accumulated metal. British journal of pharmacology, 2011, Volume: 164, Issue:2b Topics: Anemia, Iron-Deficiency; Animals; Antimicrobial Cationic Peptides; Biological Transport; Cation Transport Proteins; Cells, Cultured; Coculture Techniques; Deferiprone; Endocytosis; Erythrocytes; Hepcidins; Humans; Iron; Iron Chelating Agents; Iron Overload; K562 Cells; Macrophages; Mice; Oxidative Stress; Pyridones; Transferrin; Tumor Cells, Cultured	2011
Allosteric effects of sulfonate anions on the rates of iron release from serum transferrin. Journal of inorganic biochemistry, 2011, Volume: 105, Issue:9 Topics: Alkanesulfonates; Allosteric Site; Anions; Binding Sites; Chelating Agents; Chelation Therapy; Deferiprone; Humans; Hydroxamic Acids; Iron; Iron Overload; Kinetics; Ligands; Nitrilotriacetic Acid; Pentetic Acid; Protein Binding; Pyridones; Transferrin	2011
Quercetin as a shuttle for labile iron. Journal of inorganic biochemistry, 2012, Volume: 107, Issue:1 Topics: Animals; Antioxidants; Ascorbic Acid; Binding, Competitive; Cattle; Coordination Complexes; Deferiprone; Ferrous Compounds; Fluoresceins; HeLa Cells; Humans; Iron; Iron Chelating Agents; Oxidation-Reduction; Pyridones; Quaternary Ammonium Compounds; Quercetin; Rutin; Transferrin	2012
Iron(III)-doped, silica nanoshells: a biodegradable form of silica. Journal of the American Chemical Society, 2012, Aug-29, Volume: 134, Issue:34 Topics: Animals; Biocompatible Materials; Cattle; Deferiprone; Deferoxamine; Edetic Acid; Ferric Compounds; Humans; Iron Chelating Agents; Nanoshells; Pyridones; Serum; Silicon Dioxide; Transferrin	2012
Effect Comparison of Both Iron Chelators on Outcomes, Iron Deposit, and Iron Transporters After Intracerebral Hemorrhage in Rats. Molecular neurobiology, 2016, Volume: 53, Issue:6 Topics: Animals; Brain; Brain Edema; Cation Transport Proteins; Cerebral Hemorrhage; Clioquinol; Deferiprone; Ferritins; Hematoma; Immunohistochemistry; Iron; Iron Chelating Agents; Male; Pyridones; Rats, Sprague-Dawley; Reactive Oxygen Species; Survival Analysis; Transferrin; Treatment Outcome	2016
Successful Treatment of Iron-Overload Cardiomyopathy in Hereditary Hemochromatosis With Deferoxamine and Deferiprone. The Canadian journal of cardiology, 2016, Volume: 32, Issue:12 Topics: Cardiomyopathies; Deferiprone; Deferoxamine; Ferritins; Heart Failure; Hemochromatosis; Hemochromatosis Protein; Humans; Iron Chelating Agents; Iron Overload; Liver Diseases; Magnetic Resonance Imaging, Cine; Male; Middle Aged; Pyridones; Severity of Illness Index; Stroke Volume; Transferrin; Treatment Outcome; Ventricular Dysfunction, Left	2016
Renal iron accumulation occurs in lupus nephritis and iron chelation delays the onset of albuminuria. Scientific reports, 2017, 10-09, Volume: 7, Issue:1 Topics: Albuminuria; Animals; Deferiprone; Disease Models, Animal; Iron; Iron Chelating Agents; Iron-Binding Proteins; Kidney; Kidney Tubules; Lupus Erythematosus, Systemic; Mice; Tissue Distribution; Transferrin	2017