deferiprone and acetylcysteine

deferiprone has been researched along with acetylcysteine in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's5 (62.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Chevanne, M; Cillard, J; Cillard, P; Morel, I; Sergent, O; Sinbandhit-Tricot, S1
Amer, J; Fibach, E; Ghoti, H; Rachmilewitz, E; Winder, A1
Chattipakorn, N; Chattipakorn, SC; Fucharoen, S; Khamseekaew, J; Kumfu, S; Srichairatanakool, S; Sripetchwandee, J; Wongjaikam, S1
Chokchaichamnankit, D; Hatairaktham, S; Kalpravidh, RW; Masaratana, P; Panachan, J; Panichkul, N; Srisomsap, C; Svasti, J; Weeraphan, C1
Kontoghiorghe, CN; Kontoghiorghes, GJ1
Chattipakorn, N; Chattipakorn, SC; Fucharoen, S; Khamseekaew, J; Kumfu, S; Siri-Angkul, N; Sumneang, N1

Reviews

1 review(s) available for deferiprone and acetylcysteine

ArticleYear
Prospects for the introduction of targeted antioxidant drugs for the prevention and treatment of diseases related to free radical pathology.
    Expert opinion on investigational drugs, 2019, Volume: 28, Issue:7

    Topics: Acetylcysteine; Animals; Antioxidants; Deferiprone; Drug Design; Drug Development; Free Radical Scavengers; Free Radicals; Humans; Iron Chelating Agents; Molecular Targeted Therapy; Oxidative Stress

2019

Trials

1 trial(s) available for deferiprone and acetylcysteine

ArticleYear
Differentially expressed plasma proteins of β-thalassemia/hemoglobin E patients in response to curcuminoids/vitamin E antioxidant cocktails.
    Hematology (Amsterdam, Netherlands), 2019, Volume: 24, Issue:1

    Topics: Acetylcysteine; Adult; beta-Thalassemia; Blood Proteins; Curcumin; Deferiprone; Drug Therapy, Combination; Female; Free Radical Scavengers; Gene Expression Regulation; Hemoglobin E; Humans; Male; Vitamin E

2019

Other Studies

6 other study(ies) available for deferiprone and acetylcysteine

ArticleYear
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Glutathione depletion increases nitric oxide-induced oxidative stress in primary rat hepatocyte cultures: involvement of low-molecular-weight iron.
    Free radical biology & medicine, 2003, May-15, Volume: 34, Issue:10

    Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Cells, Cultured; Deferiprone; Ditiocarb; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Glutathione; Hepatocytes; Interferon-gamma; Iron; Iron Chelating Agents; Lipid Peroxidation; Lipopolysaccharides; Liver; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Oxidative Stress; Pyridones; Rats; Rats, Sprague-Dawley

2003
Oxidative stress in red blood cells, platelets and polymorphonuclear leukocytes from patients with myelodysplastic syndrome.
    European journal of haematology, 2007, Volume: 79, Issue:6

    Topics: Acetylcysteine; Aged; Aged, 80 and over; Antioxidants; Blood Platelets; Chelating Agents; Deferiprone; Deferoxamine; Erythrocytes; Female; Humans; Male; Myelodysplastic Syndromes; Neutrophils; Oxidative Stress; Pyridones

2007
Combined Iron Chelator and Antioxidant Exerted Greater Efficacy on Cardioprotection Than Monotherapy in Iron-Overloaded Rats.
    PloS one, 2016, Volume: 11, Issue:7

    Topics: Acetylcysteine; Animals; Benzoates; Cardiomyopathies; Cardiotonic Agents; Deferasirox; Deferiprone; Deferoxamine; Drug Combinations; Drug Synergism; Humans; Iron; Iron Chelating Agents; Iron Overload; Iron, Dietary; Male; Malondialdehyde; Mitochondria; Pyridones; Rats; Rats, Wistar; Triazoles; Ventricular Function, Left

2016
Combined iron chelator with N-acetylcysteine exerts the greatest effect on improving cardiac calcium homeostasis in iron-overloaded thalassemic mice.
    Toxicology, 2019, 11-01, Volume: 427

    Topics: Acetylcysteine; Animals; Calcium; Deferiprone; Heart; Homeostasis; Iron Chelating Agents; Iron Overload; Mice, Inbred C57BL; Myocardium; Myocytes, Cardiac; Thalassemia; Ventricular Function, Left

2019