deferiprone has been researched along with 1-ethyl-2-methyl-3-hydroxypyridin-4-one in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (30.00) | 18.7374 |
| 1990's | 5 (50.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| el-Jammal, A; Howell, PL; Li, N; Templeton, DM; Turner, MA | 1 |
| Dobbin, PS; Hall, AD; Hider, RC; Porter, JB; Sarpong, P; Taylor, PD; van der Helm, D; Xiao, G | 1 |
| Dekhordi, LS; Hider, RC; Jin, Y; Khodr, H; Liu, Z; Rai, BL | 1 |
| Carrupt, PA; Crivori, P; Cruciani, G; Testa, B | 1 |
| Hider, RC; Kayyali, R; Liu, ZD; Porter, JB; Theobald, AE | 1 |
| Caisová, D; Eybl, V; Kontoghiorghes, GJ; Koutenský, J | 1 |
| Arthur, HM; Brock, JH; Kontoghiorghes, GJ; Licéaga, J | 1 |
| Dandona, P; Hoffbrand, AV; Jeremy, JY; Kontoghiorghes, GJ | 1 |
| Kontoghiorghes, GJ | 1 |
| Hoffbrand, AV; Kontoghiorghes, GJ | 1 |
10 other study(ies) available for deferiprone and 1-ethyl-2-methyl-3-hydroxypyridin-4-one
| Article | Year |
|---|---|
Copper complexation by 3-hydroxypyridin-4-one iron chelators: structural and iron competition studies.
Topics: Antithyroid Agents; Copper; Deferiprone; Iron Chelating Agents; Ligands; Potentiometry; Pyridones; Spectrophotometry | 1994 |
Synthesis, physicochemical properties, and biological evaluation of N-substituted 2-alkyl-3-hydroxy-4(1H)-pyridinones: orally active iron chelators with clinical potential.
Topics: Administration, Oral; Animals; Crystallography; Deferoxamine; Horses; Humans; Iron; Iron Chelating Agents; Liver; Mice; Pyridones; Rats; Stereoisomerism; Structure-Activity Relationship | 1993 |
Synthesis, physicochemical properties, and evaluation of N-substituted-2-alkyl-3-hydroxy-4(1H)-pyridinones.
Topics: Animals; Bile; Ferritins; Iron; Iron Chelating Agents; Male; Molecular Conformation; Pyridones; Rats; Rats, Inbred F344; Solutions; Structure-Activity Relationship | 1998 |
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Design, synthesis, and evaluation of novel 2-substituted 3-hydroxypyridin-4-ones: structure-activity investigation of metalloenzyme inhibition by iron chelators.
Topics: Animals; Arachidonate 5-Lipoxygenase; Enzyme Inhibitors; Iron; Iron Chelating Agents; Lipoxygenase Inhibitors; Male; Pyridines; Pyridones; Rats; Rats, Wistar; Structure-Activity Relationship | 2002 |
Influence of iron chelators, 1,2-dialkyl-3-hydroxypyridin-4-ones, on the lipid peroxidation and glutathione level in the liver of mice.
Topics: Animals; Cadmium; Carbon Tetrachloride; Deferiprone; Glutathione; In Vitro Techniques; Indium; Iron; Iron Chelating Agents; Lipid Peroxidation; Liver; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Pyridones | 1991 |
Effect of novel 1-alkyl-3-hydroxy-2-methylpyrid-4-one chelators on uptake and release of iron from macrophages.
Topics: Animals; Deferiprone; Deferoxamine; Iron; Iron Chelating Agents; Iron Radioisotopes; Macrophages; Mice; Mimosine; Pyridones; Pyrones | 1990 |
The iron chelators desferrioxamine and 1-alkyl-2-methyl-3-hydroxypyrid-4-ones inhibit vascular prostacyclin synthesis in vitro.
Topics: Aluminum; Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Ascorbic Acid; Calcimycin; Deferiprone; Deferoxamine; Epinephrine; Epoprostenol; Hydrogen Peroxide; Iron; Iron Chelating Agents; Male; Pyridones; Rats; Rats, Inbred Strains | 1988 |
Dose response studies using desferrioxamine and orally active chelators in a mouse model.
Topics: Administration, Oral; Animals; Deferiprone; Deferoxamine; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Iron; Iron Chelating Agents; Male; Mice; Pyridones; Time Factors | 1986 |
Orally active alpha-ketohydroxy pyridine iron chelators intended for clinical use: in vivo studies in rabbits.
Topics: Animals; Deferiprone; Feces; Iron; Iron Chelating Agents; Pyridones; Rabbits | 1986 |