Page last updated: 2024-09-05

deferasirox and mianserin

deferasirox has been researched along with mianserin in 2 studies

Compound Research Comparison

Studies
(deferasirox)
Trials
(deferasirox)
Recent Studies (post-2010)
(deferasirox)
Studies
(mianserin)
Trials
(mianserin)
Recent Studies (post-2010) (mianserin)
8321365722,624539488

Protein Interaction Comparison

ProteinTaxonomydeferasirox (IC50)mianserin (IC50)
5-hydroxytryptamine receptor 3EHomo sapiens (human)1.4125
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.0012
5-hydroxytryptamine receptor 3BHomo sapiens (human)1.4125
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)0.163
Muscarinic acetylcholine receptor M2Homo sapiens (human)1.078
Muscarinic acetylcholine receptor M4Homo sapiens (human)2.066
5-hydroxytryptamine receptor 1AHomo sapiens (human)0.3981
Muscarinic acetylcholine receptor M5Rattus norvegicus (Norway rat)1.9
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.32
Alpha-2A adrenergic receptorHomo sapiens (human)0.0213
Muscarinic acetylcholine receptor M1Homo sapiens (human)1.423
D(2) dopamine receptorHomo sapiens (human)7.0795
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.38
Alpha-2B adrenergic receptorHomo sapiens (human)0.026
Alpha-2C adrenergic receptorHomo sapiens (human)0.0661
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.872
Alpha-2B adrenergic receptorRattus norvegicus (Norway rat)0.21
Muscarinic acetylcholine receptor M3Homo sapiens (human)1.405
D(1A) dopamine receptorHomo sapiens (human)0.543
D(4) dopamine receptorHomo sapiens (human)3.3113
Alpha-2C adrenergic receptorRattus norvegicus (Norway rat)0.21
Alpha-2A adrenergic receptorRattus norvegicus (Norway rat)0.21
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.38
Sodium-dependent noradrenaline transporter Homo sapiens (human)0.163
5-hydroxytryptamine receptor 3AMus musculus (house mouse)1.4125
Histamine H2 receptorHomo sapiens (human)1.008
Alpha-1D adrenergic receptorHomo sapiens (human)0.083
Endothelin-1 receptorHomo sapiens (human)0.1148
5-hydroxytryptamine receptor 1DHomo sapiens (human)0.3802
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.011
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.0043
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.872
Sodium-dependent serotonin transporterHomo sapiens (human)2.068
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)2.9
5-hydroxytryptamine receptor 7Homo sapiens (human)0.1148
Alpha-1A adrenergic receptorHomo sapiens (human)0.4074
Type-2 angiotensin II receptorRattus norvegicus (Norway rat)0.21
Histamine H1 receptorHomo sapiens (human)0.0024
D(3) dopamine receptorHomo sapiens (human)3.8905
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.0073
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.19
5-hydroxytryptamine receptor 3AHomo sapiens (human)1.4125
Histamine H2 receptorCavia porcellus (domestic guinea pig)0.88
5-hydroxytryptamine receptor 6Homo sapiens (human)0.085
D(2) dopamine receptorRattus norvegicus (Norway rat)3.5481
5-hydroxytryptamine receptor 3DHomo sapiens (human)1.4125
5-hydroxytryptamine receptor 3CHomo sapiens (human)1.4125
5-hydroxytryptamine receptor 3BMus musculus (house mouse)1.4125
TransporterRattus norvegicus (Norway rat)0.022

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Panderi, I; Pligoropoulou, H; Vonaparti, A1

Other Studies

2 other study(ies) available for deferasirox and mianserin

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Hydrophilic interaction liquid chromatography/positive ion electrospray mass spectrometry for the quantification of deferasirox, an oral iron chelator, in human plasma.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2012, Apr-15, Volume: 893-894

    Topics: Acetates; Acetonitriles; Adult; Benzoates; beta-Thalassemia; Chromatography, Liquid; Deferasirox; Female; Humans; Hydrophobic and Hydrophilic Interactions; Linear Models; Male; Methanol; Mianserin; Mirtazapine; Spectrometry, Mass, Electrospray Ionization; Triazoles

2012