dechloroethylcyclophosphamide has been researched along with ifosfamide in 16 studies
| Studies (dechloroethylcyclophosphamide) | Trials (dechloroethylcyclophosphamide) | Recent Studies (post-2010) (dechloroethylcyclophosphamide) | Studies (ifosfamide) | Trials (ifosfamide) | Recent Studies (post-2010) (ifosfamide) |
|---|---|---|---|---|---|
| 25 | 4 | 3 | 5,045 | 1,430 | 1,113 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.25) | 18.7374 |
| 1990's | 9 (56.25) | 18.2507 |
| 2000's | 5 (31.25) | 29.6817 |
| 2010's | 1 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Czownicki, Z; Misiura, K; Okruszek, A; Pankiewicz, K; Stec, WJ; Utracka, B | 1 |
| Gilard, V; Malet-Martino, M; Martino, R; Niemeyer, U; Pohl, J | 1 |
| Beijnen, JH; Bult, A; de Kraker, J; Kaijser, GP; Keizer, HJ; Underberg, WJ; Wiese, G | 1 |
| Idle, JR; Lind, MJ; Roberts, HL; Thatcher, N | 1 |
| Gehrcke, B; Granville, CP; König, WA; Wainer, IW | 1 |
| Kurowski, V; Wagner, T | 2 |
| Beijnen, JH; Bult, A; Kaijser, GP; Keizer, HJ; Underberg, WJ | 1 |
| Brennan, C; Hartley, JM; Nicholson, PW; Singer, JM; Souhami, RL | 1 |
| Brain, EG; Drewes, P; Gustafsson, K; Hecht, JE; Waxman, DJ; Yu, LJ | 1 |
| Beijnen, JH; Derraz, J; Huitema, AD; Jeuken, MJ; Kerbusch, T; van Putten, JW | 1 |
| Beijnen, JH; Keizer, HJ; Kerbusch, T; Mathĵt, RA; Ouwerkerk, J; Rodenhuis, S; Schellens, JH | 1 |
| Aleksa, K; Gelboin, H; Ito, S; Koren, G; Krausz, K; Matsell, D | 1 |
| Misiura, K; Zielińska, E; Zubowska, M | 1 |
| Aleksa, K; Koren, G; Nava-Ocampo, A | 1 |
| Colvin, OM; Ludeman, SM; Springer, JB | 1 |
3 trial(s) available for dechloroethylcyclophosphamide and ifosfamide
| Article | Year |
|---|---|
Urinary excretion of ifosfamide, 4-hydroxyifosfamide, 3- and 2-dechloroethylifosfamide, mesna, and dimesna in patients on fractionated intravenous ifosfamide and concomitant mesna therapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biotransformation; Carcinoma, Bronchogenic; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cyclophosphamide; Drug Administration Schedule; Female; Humans; Ifosfamide; Lung Neoplasms; Male; Mesna; Middle Aged | 1997 |
The pharmacokinetics and metabolism of ifosfamide during bolus and infusional administration: a randomized cross-over study.
Topics: Adult; Aged; Antineoplastic Agents; Biotransformation; Cross-Over Studies; Cyclophosphamide; Dexamethasone; Female; Humans; Ifosfamide; Infusions, Intravenous; Injections, Intravenous; Male; Middle Aged; Phosphoramide Mustards; Sarcoma; Sarcoma, Ewing | 1998 |
Population pharmacokinetics and exploratory pharmacodynamics of ifosfamide and metabolites after a 72-h continuous infusion in patients with soft tissue sarcoma.
Topics: Adult; Aged; Algorithms; Antineoplastic Agents, Alkylating; Cyclophosphamide; Female; Humans; Ifosfamide; Infusions, Intravenous; Male; Metabolic Clearance Rate; Middle Aged; Models, Biological; Sarcoma | 2001 |
13 other study(ies) available for dechloroethylcyclophosphamide and ifosfamide
| Article | Year |
|---|---|
Stereospecific synthesis of chiral metabolites of ifosfamide and their determination in the urine.
Topics: Cyclophosphamide; Humans; Ifosfamide; Magnetic Resonance Spectroscopy; Methods; Stereoisomerism | 1983 |
Chemical stability and fate of the cytostatic drug ifosfamide and its N-dechloroethylated metabolites in acidic aqueous solutions.
Topics: Amides; Animals; Antineoplastic Agents; Drug Stability; Female; Hydrogen-Ion Concentration; Hydrolysis; Ifosfamide; Kinetics; Lethal Dose 50; Leukemia P388; Magnetic Resonance Spectroscopy; Male; Mice; Neoplasm Transplantation; Phosphoramide Mustards; Phosphoric Acids; Phosphorus Isotopes; Rats; Tumor Cells, Cultured; Water | 1999 |
Gas chromatographic determination of 2- and 3-dechloroethylifosfamide in plasma and urine.
Topics: Chromatography, Gas; Colonic Neoplasms; Cyclophosphamide; Humans; Ifosfamide; Male; Middle Aged; Reproducibility of Results | 1992 |
The effect of route of administration and fractionation of dose on the metabolism of ifosfamide.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Chromatography, Thin Layer; Cyclophosphamide; Densitometry; Drug Administration Schedule; Humans; Ifosfamide; Infusions, Intravenous; Middle Aged; Phosphoramide Mustards | 1990 |
Determination of the enantiomers of ifosfamide and its 2- and 3-N-dechloroethylated metabolites in plasma and urine using enantioselective gas chromatography with mass spectrometric detection.
Topics: Animals; Cyclophosphamide; Female; Gas Chromatography-Mass Spectrometry; Humans; Ifosfamide; Rats; Rats, Inbred Strains; Species Specificity; Stereoisomerism; Uterine Cervical Neoplasms | 1993 |
Comparative pharmacokinetics of ifosfamide, 4-hydroxyifosfamide, chloroacetaldehyde, and 2- and 3-dechloroethylifosfamide in patients on fractionated intravenous ifosfamide therapy.
Topics: Acetaldehyde; Adult; Aged; Carcinoma, Bronchogenic; Chromatography, Gas; Chromatography, High Pressure Liquid; Cyclophosphamide; Drug Administration Schedule; Female; Humans; Ifosfamide; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged | 1993 |
Chromatographic analysis of the enantiomers of ifosfamide and some of its metabolites in plasma and urine.
Topics: Adult; Antineoplastic Agents, Alkylating; Carcinoma; Chromatography, Gas; Cyclophosphamide; Humans; Ifosfamide; Male; Rectal Neoplasms; Stereoisomerism | 1997 |
In vivo modulation of alternative pathways of P-450-catalyzed cyclophosphamide metabolism: impact on pharmacokinetics and antitumor activity.
Topics: Animals; Antineoplastic Agents; Area Under Curve; Brain Neoplasms; Cyclophosphamide; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Disease Models, Animal; Enzyme Induction; Female; Gliosarcoma; Half-Life; Hydroxylation; Ifosfamide; Liver; Male; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred F344; Troleandomycin | 1999 |
Determination of ifosfamide, 2- and 3-dechloroethyifosfamide using gas chromatography with nitrogen-phosphorus or mass spectrometry detection.
Topics: Antineoplastic Agents, Alkylating; Chromatography, Gas; Cyclophosphamide; Drug Monitoring; Gas Chromatography-Mass Spectrometry; Humans; Ifosfamide; Quality Control; Sensitivity and Specificity | 2000 |
Cytochrome P450 3A and 2B6 in the developing kidney: implications for ifosfamide nephrotoxicity.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; Aryl Hydrocarbon Hydroxylases; Blotting, Western; Child; Child, Preschool; Cyclophosphamide; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Fetus; Humans; Ifosfamide; Immunohistochemistry; Infant; Kidney; Microsomes; Middle Aged; Oxidoreductases, N-Demethylating; Stereoisomerism | 2005 |
Role of GSTM1, GSTP1, and GSTT1 gene polymorphism in ifosfamide metabolism affecting neurotoxicity and nephrotoxicity in children.
Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Child, Preschool; Cyclophosphamide; Female; Genotype; Glomerular Filtration Rate; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Ifosfamide; Infant; Kidney Diseases; Leukemia; Magnetic Resonance Spectroscopy; Male; Neurotoxicity Syndromes; Polymorphism, Genetic; Risk Factors | 2005 |
Detection and quantification of (R) and (S)-dechloroethylifosfamide metabolites in plasma from children by enantioselective LC/MS/MS.
Topics: Acetaldehyde; Adolescent; Child; Child, Preschool; Chromatography, Liquid; Cyclophosphamide; Humans; Ifosfamide; Infant; Mass Spectrometry; Pediatrics; Plasma Cells; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism | 2009 |
Labeled oxazaphosphorines for applications in mass spectrometry studies. 2. Synthesis of deuterium-labeled 2-dechloroethylcyclophosphamides and 2- and 3-dechloroethylifosfamides.
Topics: Cyclophosphamide; Deuterium; Ifosfamide; Isotope Labeling; Mass Spectrometry | 2014 |