debrisoquin has been researched along with phenobarbital in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (33.33) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Aitio, ML; Arvela, P; Bartsch, H; Béréziat, JC; Hietanen, E | 1 |
| Fujita, S; Hirobe, M; Masubuchi, Y; Narimatsu, S; Ohta, S; Suzuki, T; Tachibana, M | 1 |
| Desager, JP; Harvengt, C; Horsmans, Y; Leclercq, V; Van Nieuwenhuyze, Y | 1 |
| Strecker, M; Wolff, T | 1 |
| Birgersson, C; Blanck, A; Mellström, B; von Bahr, C; Woodhouse, K | 1 |
| Avenoso, A; Campo, GM; Caputi, AP; Perucca, E; Spina, E | 1 |
| Fujita, S; Funae, Y; Imaoka, S; Kazusaka, A; Maeda, Y; Masuda, M; Morita, K | 1 |
1 trial(s) available for debrisoquin and phenobarbital
| Article | Year |
|---|---|
Phenobarbital induces the 2-hydroxylation of desipramine.
Topics: Adult; Anticonvulsants; Antidepressive Agents, Tricyclic; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Debrisoquin; Desipramine; Enzyme Induction; Epilepsy; Half-Life; Humans; Hydroxylation; Male; Mixed Function Oxygenases; Phenobarbital; Phenotype; Polymorphism, Genetic | 1996 |
8 other study(ies) available for debrisoquin and phenobarbital
| Article | Year |
|---|---|
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Drug metabolism in rats with cancer induced by N-nitrosodiethylamine and phenobarbital.
Topics: Animals; Antipyrine; Debrisoquin; Diethylnitrosamine; Liver; Male; Microsomes, Liver; Neoplasms, Experimental; Organ Size; Phenobarbital; Rats; Rats, Wistar; Stereoisomerism; Warfarin | 1992 |
Cytochrome P450 isozymes catalyzing 4-hydroxylation of parkinsonism-related compound 1,2,3,4-tetrahydroisoquinoline in rat liver microsomes.
Topics: Amino Acid Sequence; Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Debrisoquin; Female; Isoenzymes; Isoquinolines; Kinetics; Male; Microsomes, Liver; Mixed Function Oxygenases; Molecular Sequence Data; NADPH-Ferrihemoprotein Reductase; Naphthols; Phenobarbital; Propranolol; Rabbits; Rats; Rats, Inbred Strains; Sex Characteristics; Species Specificity; Tetrahydroisoquinolines | 1992 |
Influence of rifampicin, phenobarbital and cimetidine on mixed function monooxygenase in extensive and poor metabolizers of debrisoquine.
Topics: Adult; Antipyrine; Biotransformation; Cimetidine; Debrisoquin; Half-Life; Humans; Hydroxylation; Isoquinolines; Male; Mixed Function Oxygenases; Phenobarbital; Phenotype; Rifampin | 1989 |
Lack of relationship between debrisoquine 4-hydroxylation and other cytochrome P-450 dependent reactions in rat and human liver.
Topics: Animals; Cytochrome P-450 Enzyme System; Debrisoquin; Enzyme Induction; Female; Humans; Hydroxylation; Isoquinolines; Kinetics; Male; Microsomes, Liver; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains; Sex Factors; Species Specificity | 1985 |
Comparative metabolism of debrisoquine, 7-ethoxyresorufin and benzo(a)pyrene in liver microsomes from humans, and from rats treated with cytochrome P-450 inducers.
Topics: Animals; Benzo(a)pyrene; Cytochrome P-450 Enzyme System; Debrisoquin; Enzyme Induction; Humans; In Vitro Techniques; Isoquinolines; Male; Microsomes, Liver; Oxazines; Phenobarbital; Rats; Rats, Inbred Strains | 1985 |
Strain differences in CYP3A-mediated C-8 hydroxylation (1,3,7-trimethyluric acid formation) of caffeine in Wistar and Dark Agouti rats. Rapid metabolism of caffeine in debrisoquine poor metabolizer model rats.
Topics: Aging; Animals; Aryl Hydrocarbon Hydroxylases; Caffeine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Debrisoquin; Dexamethasone; Female; Humans; Hydroxylation; Male; Methylcholanthrene; Microsomes, Liver; Oxidoreductases, N-Demethylating; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Wistar; Sex Characteristics; Species Specificity; Troleandomycin; Uric Acid | 1998 |