Compounds > debrisoquin

debrisoquin and nadp

debrisoquin has been researched along with nadp in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Araki, J; Masubuchi, Y; Narimatsu, S; Suzuki, T1
Aoyama, T; Gonzalez, FJ; Matsunaga, E; Meyer, UA; Zanger, UM; Zeugin, T1
Hardwick, JP; Meyer, UA; Vilbois, F; Zanger, UM1
Boobis, AR; Davies, DS1

Other Studies

4 other study(ies) available for debrisoquin and nadp

ArticleYear
Metabolic activation of lidocaine and covalent binding to rat liver microsomal protein.
    Biochemical pharmacology, 1992, Jun-23, Volume: 43, Issue:12

    Topics: Animals; Biotransformation; Carbon Monoxide; Cysteine; Cytochrome P-450 Enzyme System; Debrisoquin; Dose-Response Relationship, Drug; Female; Glutathione; Lidocaine; Male; Microsomes, Liver; NADP; Oxygen; Proadifen; Propranolol; Proteins; Quinidine; Rats; Rats, Inbred Strains

1992
Sequence requirements for cytochrome P-450IID1 catalytic activity. A single amino acid change (Ile380 Phe) specifically decreases Vmax of the enzyme for bufuralol but not debrisoquine hydroxylation.
    The Journal of biological chemistry, 1990, Oct-05, Volume: 265, Issue:28

    Topics: Adrenergic beta-Antagonists; Animals; Cell Line; Chimera; Cloning, Molecular; Cytochrome P-450 Enzyme System; Debrisoquin; DNA, Neoplasm; Ethanolamines; Hydroxylation; Isoleucine; Kinetics; NADP; Rats; Recombination, Genetic; Spectrophotometry; Substrate Specificity; Vaccinia virus

1990
Absence of hepatic cytochrome P450bufI causes genetically deficient debrisoquine oxidation in man.
    Biochemistry, 1988, Jul-26, Volume: 27, Issue:15

    Topics: Benzene Derivatives; Cytochrome P-450 Enzyme System; Debrisoquin; Ethanolamines; Humans; Hydroxylation; Immunologic Techniques; Immunosorbent Techniques; Isoenzymes; Isoquinolines; Kinetics; Microsomes, Liver; NADP; Polymorphism, Genetic; Stereoisomerism; Substrate Specificity

1988
Variants of human microsomal enzymes.
    Biochemical Society transactions, 1983, Volume: 11, Issue:4

    Topics: Antipyrine; Carbon Monoxide; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Debrisoquin; Humans; Isoquinolines; Microsomes, Liver; Mixed Function Oxygenases; NADP; Polymorphism, Genetic

1983