Compounds > debrisoquin

debrisoquin and mianserin

debrisoquin has been researched along with mianserin in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's1 (20.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Alm, C; Andreasson, K; Bertilsson, L; Dahl, ML; Elwin, CE; Gyllenpalm, M; Tybring, G1
Baumann, P; Eap, CB; Lima, CA; Macciardi, F; Powell, K; Woggon, B1

Other Studies

5 other study(ies) available for debrisoquin and mianserin

ArticleYear
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Stereoselective disposition of mianserin is related to debrisoquin hydroxylation polymorphism.
    Clinical pharmacology and therapeutics, 1994, Volume: 56, Issue:2

    Topics: Administration, Oral; Adult; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Debrisoquin; Female; Humans; Hydroxylation; Male; Mephenytoin; Mianserin; Middle Aged; Mixed Function Oxygenases; Polymorphism, Genetic; Stereoisomerism; Sweden; White People

1994
Steady state concentrations of the enantiomers of mianserin and desmethylmianserin in poor and in homozygous and heterozygous extensive metabolizers of debrisoquine.
    Therapeutic drug monitoring, 1998, Volume: 20, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Antihypertensive Agents; Cytochrome P-450 CYP2D6; Debrisoquin; Female; Genotype; Humans; Isomerism; Male; Mianserin; Middle Aged; White People

1998