Compounds > debrisoquin

debrisoquin and methotrimeprazine

debrisoquin has been researched along with methotrimeprazine in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's3 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Huupponen, R; Iisalo, E; Kallio, J; Säkö, E; Seppälä, M1
Brøsen, K; Meyer, UA; Zeugin, T1
Aeschlimann, JM; Balant, LP; Balant-Gorgia, AE; Dayer, P; Garrone, G; Genet, C1
Benitez, J; Buemi, AL; Caputi, AP; Cobaleda, J; Garcia, MA; Llerena, A; Piña, B; Spina, E1
Dahl, SG; Hals, PA1

Other Studies

6 other study(ies) available for debrisoquin and methotrimeprazine

ArticleYear
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
The effects of beta-adrenoceptor antagonists and levomepromazine on the metabolic ratio of debrisoquine.
    British journal of clinical pharmacology, 1990, Volume: 30, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Debrisoquin; Female; Humans; Male; Methotrimeprazine

1990
Role of P450IID6, the target of the sparteine-debrisoquin oxidation polymorphism, in the metabolism of imipramine.
    Clinical pharmacology and therapeutics, 1991, Volume: 49, Issue:6

    Topics: Antibodies; Cells, Cultured; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Debrisoquin; DNA; Humans; Imipramine; Isoenzymes; Kidney; Kinetics; Methotrimeprazine; Microsomes, Liver; Mixed Function Oxygenases; Oxidation-Reduction; Polymorphism, Genetic; Quinidine; Sparteine; Transfection

1991
Importance of oxidative polymorphism and levomepromazine treatment on the steady-state blood concentrations of clomipramine and its major metabolites.
    European journal of clinical pharmacology, 1986, Volume: 31, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anti-Anxiety Agents; Benzodiazepines; Clomipramine; Debrisoquin; Depression; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hydroxylation; Kinetics; Male; Methotrimeprazine; Middle Aged; Phenotype; Polymorphism, Genetic

1986
Debrisoquine oxidation in schizophrenic patients treated with neuroleptics.
    Pharmacological research communications, 1988, Volume: 20, Issue:12

    Topics: Adult; Aged; Antipsychotic Agents; Chlorpromazine; Debrisoquin; Female; Humans; Hydroxylation; Isoquinolines; Male; Methotrimeprazine; Middle Aged; Oxidation-Reduction; Schizophrenia; Thioridazine

1988
Effect of levomepromazine and metabolites on debrisoquine hydroxylation in the rat.
    Pharmacology & toxicology, 1994, Volume: 75, Issue:5

    Topics: Administration, Oral; Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Debrisoquin; Dose-Response Relationship, Drug; Drug Combinations; Hydroxylation; Male; Methotrimeprazine; Rats; Rats, Sprague-Dawley

1994