debrisoquin has been researched along with hydantoins in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (78.57) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Bertilsson, L; Sanz, EJ | 1 |
| Bellino, L; Black, CM; Branch, RA; Csuka, ME; May, DG; Olsen, NJ; Porter, JA; Tanner, SB; Wilkinson, GR | 1 |
| Bertilsson, L; Henthorn, TK; Sanz, E; Säwe, J; Tybring, G; Villén, T | 1 |
| Bertilsson, L; Buemi, AL; Sanz, E; Spina, E | 1 |
| Alm, C; Bertilsson, L; Sanz, EJ; Villén, T | 1 |
| Atiba, JO; Blaschke, TF; Wilkinson, GR | 1 |
| Billante, C; Jacqz, E; Mathieu, H; Moysan, F | 1 |
| Inaba, T | 1 |
| Baumann, P; Jonzier-Perey, M; Koeb, L; Küpfer, A; Schöpf, J; Tinguely, D | 1 |
| Gurtner, HP; Küpfer, A; Preisig, R; Saner, H | 1 |
| Branch, RA; Goto, F; Jacqz, E; McAllister, CB; Nakamura, K; Ray, WA; Wilkinson, GR | 1 |
| Küpfer, A; Preisig, R | 1 |
| Aslanian, WS; Branch, RA; McAllister, CB; Wedlund, PJ; Wilkinson, GR | 1 |
1 review(s) available for debrisoquin and hydantoins
| Article | Year |
|---|---|
Genetic polymorphism of mephenytoin metabolism.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Chemical Phenomena; Chemistry; China; Cytochrome P-450 CYP2C19; Debrisoquin; Dogs; Ethnicity; Humans; Hydantoins; Hydroxylation; Japan; Kinetics; Liver; Mephenytoin; Mephobarbital; Mice; Mixed Function Oxygenases; Ontario; Phenotype; Polymorphism, Genetic; Sparteine; Tennessee; White People | 1986 |
1 trial(s) available for debrisoquin and hydantoins
| Article | Year |
|---|---|
Effects of ketoconazole on the polymorphic 4-hydroxylations of S-mephenytoin and debrisoquine.
Topics: Adult; Debrisoquin; Humans; Hydantoins; Hydroxylation; Isoquinolines; Ketoconazole; Male; Mephenytoin; Oxidation-Reduction; Phenotype; Stereoisomerism | 1989 |
12 other study(ies) available for debrisoquin and hydantoins
| Article | Year |
|---|---|
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
d-Propoxyphene is a potent inhibitor of debrisoquine, but not S-mephenytoin 4-hydroxylation in vivo.
Topics: Administration, Oral; Adolescent; Adult; Debrisoquin; Dextropropoxyphene; Female; Humans; Hydantoins; Hydroxylation; Isomerism; Isoquinolines; Male; Mephenytoin; Polymorphism, Genetic | 1990 |
Scleroderma is associated with differences in individual routes of drug metabolism: a study with dapsone, debrisoquin, and mephenytoin.
Topics: Acetylation; Adult; Biotransformation; Dapsone; Debrisoquin; Disease Susceptibility; Female; Humans; Hydantoins; Hydroxylation; Isoquinolines; Logistic Models; London; Male; Mephenytoin; Middle Aged; Oxidation-Reduction; Scleroderma, Systemic; Tennessee | 1990 |
Importance of genetic factors in the regulation of diazepam metabolism: relationship to S-mephenytoin, but not debrisoquin, hydroxylation phenotype.
Topics: Adult; Benzodiazepines; Debrisoquin; Diazepam; Female; Humans; Hydantoins; Isoquinolines; Male; Mephenytoin; Mixed Function Oxygenases; Nordazepam; Phenotype; Smoking | 1989 |
Diazepam treatment does not influence the debrisoquine or mephenytoin hydroxylation phenotyping tests.
Topics: Adult; Debrisoquin; Diazepam; Drug Interactions; Humans; Hydantoins; Hydroxylation; Isoquinolines; Male; Mephenytoin; Middle Aged; Phenotype | 1989 |
S-mephenytoin hydroxylation phenotypes in a Swedish population determined after coadministration with debrisoquin.
Topics: Adolescent; Adult; Aged; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme System; Debrisoquin; Drug Interactions; Female; Humans; Hydantoins; Hydroxylation; Isoquinolines; Male; Mephenytoin; Middle Aged; Mixed Function Oxygenases; Phenotype; Sweden | 1989 |
The non-human primate: a possible model for human genetically determined polymorphisms in oxidative drug metabolism.
Topics: Animals; Biotransformation; Debrisoquin; Female; Hydantoins; Isoquinolines; Macaca; Macaca fascicularis; Male; Mephenytoin; Oxidation-Reduction; Polymorphism, Genetic | 1988 |
Amitriptyline pharmacokinetics and clinical response: II. Metabolic polymorphism assessed by hydroxylation of debrisoquine and mephenytoin.
Topics: Adult; Amitriptyline; Debrisoquin; Depressive Disorder; Female; Humans; Hydantoins; Hydroxylation; Isoquinolines; Kinetics; Male; Mephenytoin; Middle Aged; Nortriptyline; Phenotype; Polymorphism, Genetic | 1986 |
Polymorphic debrisoquine and mephenytoin hydroxylation in patients with pulmonary hypertension of vascular origin after aminorex fumarate.
Topics: Adult; Aged; Aminorex; Animals; Appetite Depressants; Debrisoquin; Female; Humans; Hydantoins; Hydroxylation; Hypertension, Pulmonary; In Vitro Techniques; Isoquinolines; Male; Mephenytoin; Microsomes, Liver; Middle Aged; Oxazoles; Phenotype; Polymorphism, Genetic; Rats; Rats, Inbred Strains | 1986 |
Interethnic differences in genetic polymorphism of debrisoquin and mephenytoin hydroxylation between Japanese and Caucasian populations.
Topics: Administration, Oral; Adolescent; Adult; Debrisoquin; Female; Genotype; Humans; Hydantoins; Hydroxylation; Isoquinolines; Japan; Male; Mephenytoin; Middle Aged; Phenotype; Random Allocation; White People | 1985 |
Pharmacogenetics of mephenytoin: a new drug hydroxylation polymorphism in man.
Topics: Adult; Debrisoquin; Female; Humans; Hydantoins; Hydroxylation; Male; Mephenytoin; Phenotype; Polymorphism, Genetic | 1984 |
Mephenytoin hydroxylation deficiency in Caucasians: frequency of a new oxidative drug metabolism polymorphism.
Topics: Administration, Oral; Adolescent; Adult; Chromatography, High Pressure Liquid; Debrisoquin; Female; Humans; Hydantoins; Hydroxylation; Male; Mephenytoin; Middle Aged; Phenotype; Polymorphism, Genetic; Tennessee; White People | 1984 |