debrisoquin and clomipramine

debrisoquin has been researched along with clomipramine in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's1 (12.50)18.2507
2000's2 (25.00)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Brøsen, K; Gram, LF; Nielsen, KK1
Balant, LP; Balant-Gorgia, AE; Garrone, G1
Aeschlimann, JM; Balant, LP; Balant-Gorgia, AE; Dayer, P; Garrone, G; Genet, C1
Balant, L; Balant-Gorgia, AE; Zysset, T1
Bertilsson, L1

Reviews

1 review(s) available for debrisoquin and clomipramine

ArticleYear
Metabolism of antidepressant and neuroleptic drugs by cytochrome p450s: clinical and interethnic aspects.
    Clinical pharmacology and therapeutics, 2007, Volume: 82, Issue:5

    Topics: Antidepressive Agents; Antipsychotic Agents; Aryl Hydrocarbon Hydroxylases; Asian People; Clomipramine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Debrisoquin; Drug Interactions; Ethnicity; Humans; Mediterranean Region; Metabolic Networks and Pathways; Mixed Function Oxygenases; Mutation; Nortriptyline; Polymorphism, Genetic; Sweden; White People

2007

Trials

1 trial(s) available for debrisoquin and clomipramine

ArticleYear
Steady-state plasma levels of clomipramine and its metabolites: impact of the sparteine/debrisoquine oxidation polymorphism. Danish University Antidepressant Group.
    European journal of clinical pharmacology, 1992, Volume: 43, Issue:4

    Topics: Adult; Aged; Clomipramine; Cytochrome P-450 Enzyme System; Debrisoquin; Depression; Female; Humans; Male; Middle Aged; Oxidation-Reduction; Phenotype; Polymorphism, Genetic; Sparteine

1992

Other Studies

6 other study(ies) available for debrisoquin and clomipramine

ArticleYear
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
High blood concentrations of imipramine or clomipramine and therapeutic failure: a case report study using drug monitoring data.
    Therapeutic drug monitoring, 1989, Volume: 11, Issue:4

    Topics: Aged; Clomipramine; Debrisoquin; Depressive Disorder; Female; Humans; Hydroxylation; Imipramine; Middle Aged; Monitoring, Physiologic; Phenotype; Psychiatric Status Rating Scales

1989
Importance of oxidative polymorphism and levomepromazine treatment on the steady-state blood concentrations of clomipramine and its major metabolites.
    European journal of clinical pharmacology, 1986, Volume: 31, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anti-Anxiety Agents; Benzodiazepines; Clomipramine; Debrisoquin; Depression; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hydroxylation; Kinetics; Male; Methotrimeprazine; Middle Aged; Phenotype; Polymorphism, Genetic

1986
High plasma concentrations of desmethylclomipramine after chronic administration of clomipramine to a poor metabolizer.
    European journal of clinical pharmacology, 1987, Volume: 32, Issue:1

    Topics: Allopurinol; Clomipramine; Debrisoquin; Depressive Disorder; Female; Humans; Hydroxylation; Kinetics; Middle Aged

1987