ddt has been researched along with phenobarbital in 168 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 146 (86.90) | 18.7374 |
| 1990's | 16 (9.52) | 18.2507 |
| 2000's | 4 (2.38) | 29.6817 |
| 2010's | 2 (1.19) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Duffy, EM; Jorgensen, WL | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Breyer, U; Junginger, W; Villumsen, D | 1 |
| Artigou, JY; Benhamou, JP; Descatoire, V; Pessayre, D; Wandscheer, JC | 1 |
| Araya, O; Evans, J; Ford, EJ; Rivera, R | 1 |
| Chasseaud, LF; Down, WH | 1 |
| Nishizumi, M | 1 |
| Edwards, PM | 1 |
| Ford, JH; Gopinath, C | 1 |
| Gralla, EJ | 1 |
| Popov, CS; Popova, MP; Vultcheva, GM; Yantchev, I | 1 |
| Kupfer, D; Miranda, GK; Navarro, J; Piccolo, DE; Theoharides, AD | 1 |
| Butler, WH; Jones, G | 1 |
| Conney, AH; Jacobson, MM; Levin, W | 1 |
| Ferrando, R; Gak, JC; Graillot, C; Truhaut, R | 1 |
| Jansen, JD | 1 |
| Ravera, M; Repetti, G; Rossi, L; Santi, L | 1 |
| Ford, EJ; Gopinath, G | 1 |
| Chhabra, RS; Fouts, JR; Philpot, RM; Tredger, JM | 1 |
| Gartner, LM; Vaisman, SL | 1 |
| Christopher, JP; Fry, RJ; Peraino, C; Staffeldt, E | 1 |
| Brodeur, J; Lambert, G | 3 |
| Gangolli, SD; Lake, BG; Lloyd, AG; Longland, RC | 1 |
| Adenuga, GA; Bababunmi, EA; Hendrickse, RG | 1 |
| Chauhan, DP; Diwan, BA; Dragnev, KH; Jones, CR; Lubet, RA; Miller, MS; Nims, RW; Rice, JM; Ward, JM | 1 |
| Hatolkar, VS; Pawar, SS | 2 |
| Klaunig, JE; Ruch, RJ; Weghorst, CM | 1 |
| Bai, L; Miyazaki, M; Sato, J | 1 |
| Edwards, AM; Lucas, CM | 1 |
| Klaunig, JE; Ruch, RJ | 3 |
| Klaunig, JE; Pereira, MA; Ruch, RJ | 1 |
| McLamb, RL; Shaw, S; Tilson, HA | 1 |
| Glatt, HR; Oesch, F | 1 |
| Büsser, MT; Lutz, WK | 1 |
| Belitsky, GA; Budunova, IV; Mittelman, LA | 1 |
| de Gerlache, J; Lans, M; Préat, V; Roberfroid, M; Taper, H | 1 |
| Belitskiĭ, GA; Budunova, IV; Mittel'man, LA | 1 |
| Mori, H; Tanaka, T; Williams, GM | 1 |
| Hoover, KL; Poirier, LA; Shivapurkar, N | 1 |
| Yamasaki, H; Zeilmaker, MJ | 1 |
| Kitagawa, T | 1 |
| Brandt, I; Klasson-Wehler, E; Lund, BO | 1 |
| Mori, H; Sugie, S; Takahashi, M | 1 |
| Banerjee, BD; Zaidi, SS | 1 |
| Doki, M; Puga, FR; Rodrigues, MA | 1 |
| Nousiainen, U | 1 |
| Das, M; Mukhtar, H; Seth, PK; Srivastava, SP | 1 |
| Dietz, D; Kornbrust, D | 1 |
| Chadwick, RW; Cranmer, MF; Peoples, AJ | 1 |
| Kutt, H | 1 |
| Gielen, JE; Nebert, DW | 2 |
| Bye, A; Chang, R; Conney, AH; Finster, M; Jacobson, M; Kuntzman, R; Munro-Faure, AD; Peck, AW; Poland, A; Poppers, PJ; Welch, R; Wolff, JA | 1 |
| Denburg, JL; O'Brien, RD | 1 |
| Thorpe, E; Walker, AI | 1 |
| Remmer, H | 2 |
| Kar, PP; Matin, MA | 1 |
| Creaven, PJ; Davies, WH | 1 |
| Conney, AH; Kuntzman, R; Welch, R | 1 |
| McLean, AE; Pilcher, CW; Stathers, GM; Thompson, RP | 1 |
| Barquet, A; Carter, CH; Davies, JE; Edmundson, WF | 1 |
| Davies, PA | 1 |
| Ferrando, R; Fourlon, C; Gautier, F; Henry, N; N'Diaye, AL | 1 |
| Greim, H; Remmer, H; Ueberberg, H | 1 |
| Uehleke, H | 1 |
| Greim, H; Uehleke, H | 1 |
| Netter, KJ | 1 |
| Cockrill, BL; Platt, DS | 1 |
| Murphy, SD; Szot, RJ | 1 |
| Conney, AH; Kuntzman, R; Sansur, M | 1 |
| Conney, AH; Jacobson, M; Kuntzman, R; Levin, W; Schneidman, K | 1 |
| Hagihara, B; Ichikawa, Y; Yamano, T | 1 |
| Arnold, K; Gerber, N | 1 |
| Agosin, M; Gil, L; Letelier, ME; Scaramelli, N | 1 |
| Brodeur, J; Gascon, AL | 1 |
| Carlson, GP; DuBois, KP | 1 |
| Mattocks, AR; White, IN | 1 |
| McIntosh, DA; Topham, JC | 1 |
| Fouts, JR | 1 |
| Allen, JG; Seawright, AA | 1 |
| Litterst, CL; Van Loon, EJ | 1 |
| Jori, A; Pugliatti, C; Santini, V | 1 |
| Bick, M; Fishbein, L | 1 |
| Bolt, HM; Kappus, H; Remmer, H | 1 |
| Gilles, FH; Kaplan, ML; Murphy, SD | 1 |
| Chhabra, RS; Fouts, JR | 2 |
| Rappolt, RT | 1 |
| Yobs, AR | 1 |
| Makar, AB; Zeitoun, R | 1 |
| Filippich, LJ; Seawright, AA; Steele, DP | 1 |
| Matschiner, JT; Willingham, AK | 1 |
| Hänninen, O; Marselos, M | 1 |
| Stenger, RJ | 1 |
| Clodi, PH | 1 |
| Lipsett, MB | 1 |
| Hazeltine, W | 1 |
| Burns, JJ | 1 |
| Arias, IM; Gatmaitan, Z; Levi, AJ; Levine, R; Reyes, H | 1 |
| Bishop, R; Mudie, AW; Seawright, AA; Steele, DP | 1 |
| Chen, TS; DuBois, KP; Kinoshita, FK | 1 |
| Fries, GF; Gordon, CH; Lester, JW; Marrow, GS | 1 |
| Arias, IM; Gatmaitan, Z; Levi, AJ; Reyes, H | 1 |
| Fouts, JR; Kutt, H; Waters, L | 2 |
| Cook, RM; Wilson, KA | 1 |
| Kwalick, DS | 1 |
| Aust, SD; Stevens, JB | 1 |
| Henderson, PT | 1 |
| Magour, S; Nievel, JG | 1 |
| Lechner, MC; Pousada, CR | 1 |
| McLean, AE | 2 |
| Cloutier, G; Gascon, AL | 1 |
| Abernathy, CO; Guthrie, FE; Hodgson, E; Philpot, RM | 1 |
| Copsey, K; Deichmann, WB; Hamill, T; MacDonald, WE; MacQueen, J | 1 |
| Arias, IM | 1 |
| Bianchetti, A; Jori, A; Prestini, PE | 1 |
| Chevrel, B; Hecht, Y | 1 |
| Davies, JE; Edmundson, WF; Maceo, A; Morgade, C | 1 |
| Magee, PN; McLean, AE | 1 |
| Dezoteux, H; Vinceneux, P | 1 |
| Black, M | 1 |
| Fowler, JS | 1 |
| Alary, JG; Brodeur, J; Guay, P | 1 |
| Fouts, JR; Kutt, H | 1 |
| Ecobichon, DJ; Schwark, WS | 1 |
| Burns, JJ; Conney, AH; Ikeda, M | 1 |
| Alary, JG; Brodeur, J; Côté, MG; Guay, P; Lamothe, P; Panisset, JC | 1 |
| McLean, AE; Verschuuren, HG | 1 |
| Sánchez, E | 1 |
| Hino, O; Kitagawa, T; Nomura, K; Sugano, H | 1 |
| Campbell, MA; Gyorkos, J; Homonko, K; Leece, B; Safe, S | 1 |
| Barbieri, O; Cabral, JR; Rossi, L; Santi, L | 1 |
| Bock, KW; Lilienblum, W; Walli, AK | 1 |
| Braun, W; Dräger, J; Reymann, A | 1 |
| Poirier, LA; Shivapurkar, N | 1 |
| Jaffery, FN; Matin, MA; Siddiqui, RA | 1 |
| Mackenroth, T; Siegers, CP; Younes, M | 1 |
| Clark, CR; Ferguson, PW; Gee, SJ; Krieger, RI | 1 |
| Borisova, LN; Kovalev, IE | 1 |
| Madhukar, BV; Matsumura, F | 1 |
| Leibold, E; Schwarz, LR | 1 |
| Armellini, R; Guerrieri, P; Liotti, FS; Mariucci, G; Menghini, AR | 1 |
| Jansen, LA; Jongen, WM | 1 |
| Morimoto, S | 1 |
| Dragnev, KH; Lubet, RA; Nims, RW | 1 |
| Amichot, M; Berge, J; Brun, A; Cuany, A; Le Mouel, T | 1 |
| McGlynn, H; Morrow, DM; Ryan, MP | 1 |
| Kostka, G; Palut, D; Wiadrowska, B | 1 |
| Mehta, PP; Ren, P; Ruch, RJ | 1 |
| Buchmann, A; Buenemann, CL; Schmiechen, A; Schwarz, M; Stroh, C; Willy, C | 1 |
| Acharya, C; Andersen, MR; Omiecinski, CJ; Schilter, B | 1 |
| Edwards, AM; Lee, CH | 1 |
| ZAVON, MR | 1 |
| Horner, MA; King-Jones, K; Lam, G; Thummel, CS | 1 |
| Ganguly, R; Kuruganti, S; Lam, V; Lucchesi, JC; Morra, R | 1 |
14 review(s) available for ddt and phenobarbital
| Article | Year |
|---|---|
Sub-threshold levels of dietary chemicals and mixed function oxidase induction.
Topics: Animals; DDT; Diet; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Induction; Inactivation, Metabolic; Liver; Male; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Rats | 1978 |
Effects of drugs on the metabolism of bilirubin and other normal body constituents.
Topics: Animals; Bilirubin; DDT; Estrogens; Female; Glucuronates; Humans; Hydroxylation; Infant; Infant, Newborn; Jaundice, Neonatal; Liver; Male; Microsomes, Liver; Pharmacology; Phenobarbital; Pregnancy; Steroids; Testosterone; Thyroxine; Transferases | 1976 |
Pharmacologic treatment of neonatal hyperbilirubinemia.
Topics: Adolescent; Animals; Aspartic Acid; Bilirubin; DDT; Diazepam; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Ethanol; Female; Heroin; Humans; Infant; Infant, Newborn; Intestinal Absorption; Jaundice, Neonatal; Liver; Male; Microsomes, Liver; Nikethamide; Orotic Acid; Phenobarbital; Phototherapy; Serum Albumin; Stimulation, Chemical | 1975 |
Species differences in enzymes controlling reactive epoxides.
Topics: Animals; Benzo(a)pyrene; DDT; Epoxide Hydrolases; Epoxy Compounds; Ethers, Cyclic; Female; Hexachlorocyclohexane; Liver; Liver Neoplasms, Experimental; Male; Mice; Phenobarbital; Species Specificity | 1987 |
Biochemical and genetic factors regulating dilantin metabolism in man.
Topics: Aminosalicylic Acids; Animals; Ataxia; Cats; Chlordan; Cycloserine; DDT; Dicumarol; Disulfiram; Enzyme Induction; Female; Genetics, Medical; Humans; Intestinal Absorption; Isoniazid; Kinetics; Liver Diseases; Male; Metabolism; Microsomes, Liver; Nystagmus, Pathologic; Pedigree; Pharmacogenetics; Phenobarbital; Phenytoin; Rats; Thiazines | 1971 |
Effects of environmental chemicals on the metabolism of drugs, carcinogens, and normal body constituents in man.
Topics: 17-Ketosteroids; Alcohols; Androstanes; Animals; Antipyrine; Azo Compounds; Benzopyrenes; Bilirubin; DDT; Dioxoles; Environmental Exposure; Enzyme Induction; Estradiol; Estrone; Ethers; Female; Half-Life; Humans; Hydrocortisone; Infant, Newborn; Male; Metabolism; Mice; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Phenylbutazone; Placenta; Polycyclic Compounds; Pregnancy; Rats; Smoking | 1971 |
Factors influencing steroid hydroxylases in liver microsomes.
Topics: Age Factors; Animals; Carbon Isotopes; Chlordan; DDT; Dogs; Estradiol; Guinea Pigs; Hexobarbital; In Vitro Techniques; Insecticides; Liver; Mice; Microsomes; Mixed Function Oxygenases; NADP; Oxygen Consumption; Phenobarbital; Phenylbutazone; Phosphates; Polycyclic Compounds; Proadifen; Progesterone; Rabbits; Rats; Sex Factors; Steroids; Testosterone | 1966 |
Current trends in hepatic response tests.
Topics: Aminopyrine; Animals; Ascorbic Acid; Circadian Rhythm; Cold Temperature; Cytochromes; DDT; Dietary Carbohydrates; Dietary Proteins; Dogs; Enzyme Induction; Guinea Pigs; Hepatomegaly; Hexobarbital; Humans; Hydrocarbons; Liver; Mice; Microsomes, Liver; NADP; Organ Size; Phenobarbital; Rabbits; Rats | 1969 |
Organelle pathology of the liver. The endoplasmic reticulum.
Topics: Animals; Chlordan; DDT; Endoplasmic Reticulum; Ethanol; Glycogen; Lipid Metabolism; Liver; Liver Diseases; Necrosis; Nikethamide; Phenobarbital; Protein Biosynthesis; Rats; Tolbutamide | 1970 |
Microsomes, metabolism and toxicity.
Topics: Animals; Barbiturates; Biotransformation; Carbon Tetrachloride; DDT; Enzyme Induction; Female; Hexobarbital; Male; Methylcholanthrene; Mice; Microsomes, Liver; Pesticides; Phenobarbital; Pituitary Hormones, Anterior; Protein Deficiency; Rabbits; Rats; Steroids; Toxicology | 1969 |
[Detoxification function of the liver].
Topics: Animals; Bilirubin; Biological Transport; DDT; Dogs; Ethanol; Female; Glycolysis; Humans; Liver; Liver Circulation; Liver Diseases; Liver Function Tests; Male; Phenobarbital; Poisons; Sulfobromophthalein | 1970 |
Factors influencng the rate of metabolism of steroid hormones in man.
Topics: Aldosterone; Androgens; Barbiturates; DDT; Dichlorodiphenyldichloroethane; Estradiol; Estrogens; Hormones; Humans; Hydrocortisone; Metabolism; Microsomes, Liver; Phenobarbital; Phenytoin; Progesterone; Protein Binding; Steroids; Testosterone; Thyroxine | 1971 |
DDT and juvenile jaundice.
Topics: Animals; Breast Feeding; DDT; Enzyme Induction; Female; Humans; Hyperbilirubinemia; Infant Food; Infant, Newborn; Jaundice, Neonatal; Ketones; Maternal-Fetal Exchange; Milk; Milk, Human; Organophosphorus Compounds; Pesticides; Phenobarbital; Pregnancy; Pregnanes | 1971 |
Report of ICPEMC Task Group 5 on the differentiation between genotoxic and non-genotoxic carcinogens.
Topics: Animals; Butylated Hydroxytoluene; Carcinogens; Cell Line; DDT; Dieldrin; Dioxins; Drug Evaluation, Preclinical; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Mutagenicity Tests; Mutagens; Neoplasms; Phenobarbital; Structure-Activity Relationship | 1984 |
154 other study(ies) available for ddt and phenobarbital
| Article | Year |
|---|---|
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Phenobarbital-induced prolongation of half-life and alteration of distribution of a phenothiazine drug metabolite in the rat.
Topics: Animals; Antipsychotic Agents; Cytochrome P-450 Enzyme System; DDT; Half-Life; In Vitro Techniques; Kidney; Male; Microsomes, Liver; Morphine Derivatives; Perazine; Phenobarbital; Proadifen; Rats; Time Factors | 1976 |
Formation and inactivation of a chemically reactive metabolite of vinyl chloride.
Topics: Animals; Cysteine; Cytochrome P-450 Enzyme System; DDT; Epoxide Hydrolases; Epoxy Compounds; Glutathione; Hydrocarbons, Chlorinated; Male; Microsomes, Liver; NADP; Phenobarbital; Proadifen; Protein Binding; Rats; Vinyl Chloride; Vinyl Compounds | 1979 |
Ford EJ.
Topics: Aminopyrine N-Demethylase; Animals; Cattle; DDT; Dieldrin; Female; Hexachlorocyclohexane; Horses; Liver; Male; Phenobarbital; Sheep; Species Specificity; Stimulation, Chemical; Time Factors | 1976 |
Effect of repeated oral administration of phenobarbitone or DDT on hepatic glutathione S-transferase activity in nonhuman primates: comparison with the rat.
Topics: Animals; Cytosol; DDT; Glutathione Transferase; Haplorhini; Liver; Macaca mulatta; Male; Organ Size; Papio; Phenobarbital; Proteins; Rats | 1979 |
Effect of phenobarbital, dichlorodiphenyltrichloroethane, and polychlorinated biphenyls on diethylnitrosamine-induced hepatocarcinogenesis.
Topics: Animals; DDT; Diethylnitrosamine; Drug Synergism; Enzyme Induction; Liver Neoplasms, Experimental; Male; Nitrosamines; Phenobarbital; Polychlorinated Biphenyls; Rats | 1979 |
Neurotoxicity of acrylamide and its analogues and effects of these analogues and other agents on acrylamide neuropathy.
Topics: Acrylamides; Animals; Ataxia; Brachial Plexus; Chickens; DDT; Female; Goldfish; Male; Nerve Degeneration; Peripheral Nervous System Diseases; Peroneal Nerve; Phenobarbital; Rana temporaria; Rats; Sciatic Nerve; Species Specificity; Spinal Cord; Vitamin A; Vitamin E | 1975 |
The role of microsomal hydroxylases in the modification of chloroform hepatotoxicity in rats.
Topics: Animals; Carbon Disulfide; Chemical and Drug Induced Liver Injury; Chloroform; Chlorpromazine; DDT; Ditiocarb; Drug Interactions; Enzyme Induction; Female; Hexobarbital; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Phenobarbital; Phenylbutazone; Proadifen; Rats; Sleep | 1975 |
Drug interaction.
Topics: Animals; Biological Transport, Active; Blood Urea Nitrogen; DDT; Drug Antagonism; Drug Interactions; Drug Therapy; Gastric Mucosa; Glomerular Filtration Rate; Hydrogen-Ion Concentration; Intestinal Absorption; Microsomes, Liver; Pharmaceutical Preparations; Phenobarbital; Protein Binding; Rats | 1975 |
Effect of different factors modifying the activity of some enzyme systems of the endoplasmic reticulum on the sensitivity of cell organelles against the damaging action of chemical agents. II. Studies with chlorpromazine, 2,4-dinitrophenol, phenobarbital
Topics: Acid Phosphatase; Animals; Chlorpromazine; DDT; Diet; Dinitrophenols; Endoplasmic Reticulum; Female; Intracellular Membranes; Liver; Lysosomes; Male; Microbodies; Phenobarbital; Rats; Stress, Physiological | 1979 |
Effect of inducers and inhibitors of monooxygenase on the hydroxylation of prostaglandins in the guinea pig. Evidence for several monooxygenases catalyzing omega- and omega-1-hydroxylation.
Topics: Animals; Aroclors; Benzopyrenes; Chromatography, High Pressure Liquid; DDT; Enzyme Induction; Guinea Pigs; Hydroxylation; Male; Mass Spectrometry; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Prostaglandins A; Prostaglandins E | 1979 |
Pathological and toxicological data on chlorinated pesticides and phenobarbital.
Topics: Animals; Body Weight; Carcinogens; DDT; Drug Interactions; Female; Insecticides; Liver Neoplasms; Male; Mice; Phenobarbital; Rats | 1978 |
[The sensitivity of chickens, compared to other animal species, to the classic inducers of cytochrome P-450].
Topics: Animals; Chickens; Cytochrome P-450 Enzyme System; DDT; Enzyme Induction; Liver; Male; Phenobarbital; Vitamin A | 1975 |
Medical and toxicological research on dieldrin and related compounds.
Topics: Adult; Animals; Carcinogens; DDT; Dieldrin; Dogs; Haplorhini; Humans; Liver Neoplasms; Male; Maximum Allowable Concentration; Mice; Microsomes, Liver; Middle Aged; Netherlands; Occupational Medicine; Phenobarbital; Rats; United Kingdom | 1976 |
Long-term administration of DDT or phenobarbital-Na in Wistar rats.
Topics: Age Factors; Animals; Body Weight; DDT; Drug Administration Schedule; Female; Liver Neoplasms; Male; Neoplasms, Experimental; Phenobarbital; Rats; Sex Factors | 1977 |
The influence of hepatic microsomal amidopyrine demethylase activity on halothane hepatotoxicity in the horse.
Topics: Aminopyrine N-Demethylase; Animals; Carbon Disulfide; Chemical and Drug Induced Liver Injury; Chlorpromazine; DDT; Halothane; Horses; Liver; Microsomes, Liver; Necrosis; Phenobarbital | 1976 |
Relationship between induction of aryl hydrocarbon hydroxylase and de novo synthesis of cytochrome P-448 (P1-450) in mice.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzopyrenes; Cytochrome P-450 Enzyme System; DDT; Enzyme Induction; Kinetics; Male; Methylcholanthrene; Mice; Mice, Inbred Strains; Microsomes, Liver; Phenobarbital; Polychlorinated Dibenzodioxins; Species Specificity | 1976 |
Comparative enhancing effects of phenobarbital, amobarbital, diphenylhydantoin, and dichlorodiphenyltrichloroethane on 2-acetylaminofluorene-induced hepatic tumorigenesis in the rat.
Topics: 2-Acetylaminofluorene; Amobarbital; Animals; DDT; DNA, Neoplasm; Drug Synergism; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Organ Size; Phenobarbital; Phenytoin; Rats | 1975 |
[The effect of pretreatment with enzyme inducers on the acute toxicity of DDT (1, 1-bis-(p-chlorophenyl)-2,2,2-trichloroethane) in rats].
Topics: Animals; Brain; DDT; Drug Interactions; Enzyme Induction; Female; Liver; Methylcholanthrene; Norethandrolone; Phenobarbital; Rats | 1975 |
The influence of some foreign compounds on hepatic xenobiotic metabolism and the urinary excretion of D-glucuronic acid metabolites in the rat.
Topics: Animals; Butylated Hydroxytoluene; DDT; Female; Glucuronates; Liver; Male; Methylcholanthrene; Phenobarbital; Pregnenolone Carbonitrile; Rats; Time Factors | 1976 |
[Influence of various enzyme inductors and combinations of inductors on DDT residue elimination in rats].
Topics: Abdomen; Adipose Tissue; Animals; Benzopyrenes; Brain; DDT; Dichlorodiphenyl Dichloroethylene; Dichlorodiphenyldichloroethane; Enzyme Induction; Female; Kidney; Liver; Norethandrolone; Pesticide Residues; Phenobarbital; Rats | 1976 |
Influence of starvation and hepatic microsomal enzyme induction on the mobilization of DDT residues in rats.
Topics: Animals; DDT; Enzyme Induction; Male; Microsomes, Liver; Pesticide Residues; Phenobarbital; Rats; Starvation; Time Factors | 1976 |
Depression of the Ca(2+)-ATPase activity of the rat liver endoplasmic reticulum by the liver tumour promoters, 1,1,1-trichloro-2,2-bis(p-chlorophenyl)-ethane and phenobarbital.
Topics: Animals; Calcium-Transporting ATPases; Carcinogens; DDT; Endoplasmic Reticulum; gamma-Glutamyltransferase; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains | 1992 |
A pleiotropic response to phenobarbital-type enzyme inducers in the F344/NCr rat. Effects of chemicals of varied structure.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Base Sequence; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; DDT; Enzyme Induction; Epoxide Hydrolases; Glucuronosyltransferase; Glutathione Transferase; Liver; Male; Molecular Sequence Data; Oligonucleotide Probes; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred F344; RNA; Steroid Hydroxylases; Xenobiotics | 1992 |
Hepatic mixed function oxidase system and effect of phenobarbital, 3-methylcholanthrene and 1, 1, 1-trichloro-2, 2-bis(p-chlorophenyl)ethane in developing chickens.
Topics: Animals; Chickens; DDT; Enzyme Induction; Hydrogen Peroxide; Liver; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Stimulation, Chemical | 1992 |
Comparative effects of phenobarbital, DDT, and lindane on mouse hepatocyte gap junctional intercellular communication.
Topics: Animals; Cell Communication; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; DDT; Dose-Response Relationship, Drug; Hexachlorocyclohexane; Hydrocarbons, Chlorinated; Intercellular Junctions; Liver; Male; Mice; Phenobarbital; Pyridines | 1990 |
Influence of liver tumor promoters and structurally related chemicals on survival of normal adult rat hepatocytes in primary culture.
Topics: Animals; Barbital; Butylated Hydroxytoluene; Carcinogens; Cell Survival; Cells, Cultured; DDT; DNA; Liver; Liver Neoplasms, Experimental; Male; Phenobarbital; Rats | 1990 |
Phenobarbital and some other liver tumor promoters stimulate DNA synthesis in cultured rat hepatocytes.
Topics: Animals; Carcinogens; Cells, Cultured; DDT; Dexamethasone; DNA; Hexachlorocyclohexane; Kinetics; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains | 1985 |
Antioxidant prevention of tumor promoter induced inhibition of mouse hepatocyte intercellular communication.
Topics: Animals; Antioxidants; Carcinogens; Cell Communication; DDT; Dose-Response Relationship, Drug; Free Radicals; Hexachlorocyclohexane; Liver; Male; Mice; Mice, Inbred Strains; Phenobarbital; Superoxide Dismutase | 1986 |
Inhibition of intercellular communication between mouse hepatocytes by tumor promoters.
Topics: Animals; Aroclors; Carcinogens; Cell Communication; Cells, Cultured; Chlorodiphenyl (54% Chlorine); DDT; Dimethyl Sulfoxide; Hexachlorocyclohexane; Liver; Male; Mice; Phenobarbital; RNA; Tetradecanoylphorbol Acetate; Uridine | 1987 |
The effects of lindane, DDT, and chlordecone on avoidance responding and seizure activity.
Topics: Animals; Avoidance Learning; Chlordecone; Chlordiazepoxide; DDT; Dose-Response Relationship, Drug; Hexachlorocyclohexane; Insecticides; Learning; Male; Memory; Phenobarbital; Phenytoin; Rats; Rats, Inbred F344; Seizures | 1987 |
Stimulation of DNA synthesis in rat and mouse liver by various tumor promoters.
Topics: Adipates; Aflatoxin B1; Aflatoxins; Aldrin; Animals; Benzidines; Biological Availability; Carbon Tetrachloride; Carcinogens; Cell Division; Circadian Rhythm; DDT; Diethylhexyl Phthalate; DNA; DNA Replication; Female; Hexachlorocyclohexane; Isomerism; Liver; Liver Neoplasms; Male; Mice; Phenobarbital; Polychlorinated Dibenzodioxins; Rats; Thioacetamide | 1987 |
Identification of tumor promoters by their inhibitory effect on intercellular transfer of lucifer yellow.
Topics: Animals; Anthralin; Butylated Hydroxytoluene; Calcimycin; Carcinogens; Cells, Cultured; Cricetinae; DDT; Diterpenes; Fluorescent Dyes; Intercellular Junctions; Isoquinolines; Lyngbya Toxins; Phenobarbital; Terpenes; Tetradecanoylphorbol Acetate | 1989 |
Role of cyclic AMP in the inhibition of mouse hepatocyte intercellular communication by liver tumor promoters.
Topics: Animals; Bucladesine; Carcinogens; Cell Communication; Cells, Cultured; Cyclic AMP; DDT; Kinetics; L-Lactate Dehydrogenase; Liver; Male; Mice; Mice, Inbred Strains; Phenobarbital | 1987 |
Comparative analysis of the effect of phenobarbital, dichlorodiphenyltrichloroethane, butylated hydroxytoluene and nafenopin on rat hepatocarcinogenesis.
Topics: Animals; Butylated Hydroxytoluene; Cocarcinogenesis; DDT; gamma-Glutamyltransferase; Liver Neoplasms, Experimental; Nafenopin; Phenobarbital; Precancerous Conditions; Rats | 1986 |
[Possibility of identifying tumor promoters by their inhibitory action on the intercellular exchange of lucifer yellow].
Topics: Animals; Anthralin; Butylated Hydroxytoluene; Calcimycin; Carcinogens; Cell Line; Cricetinae; DDT; Diterpenes; Fluorescent Dyes; In Vitro Techniques; Isoquinolines; Phenobarbital; Terpenes; Tetradecanoylphorbol Acetate | 1987 |
Enhancement of dimethylnitrosamine-initiated hepatocarcinogenesis in hamsters by subsequent administration of carbon tetrachloride but not phenobarbital or p,p'-dichlorodiphenyltrichloroethane.
Topics: Animals; Carbon Tetrachloride; Cocarcinogenesis; Cricetinae; DDT; Dimethylnitrosamine; Liver Neoplasms, Experimental; Male; Mesocricetus; Phenobarbital; Species Specificity | 1987 |
Strain and species effects on the inhibition of hepatocyte intercellular communication by liver tumor promoters.
Topics: Animals; Carcinogens; Cell Communication; Cells, Cultured; Cocarcinogenesis; DDT; Dieldrin; Liver; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred Strains; Phenobarbital; Rats; Rats, Inbred F344; Species Specificity; Uridine | 1987 |
Effect of methionine and choline on liver tumor promotion by phenobarbital and DDT in diethylnitrosamine-initiated rats.
Topics: Adenocarcinoma; Animals; Choline; Cocarcinogenesis; DDT; Diethylnitrosamine; Liver Neoplasms; Lung Neoplasms; Male; Methionine; Phenobarbital; Prohibitins; Rats; Rats, Inbred F344; Weaning | 1986 |
Inhibition of junctional intercellular communication as a possible short-term test to detect tumor-promoting agents: results with nine chemicals tested by dye transfer assay in Chinese hamster V79 cells.
Topics: Animals; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Carcinogens; Cell Communication; Cells, Cultured; Cricetinae; Cricetulus; DDT; Isoquinolines; Phenobarbital; Tetradecanoylphorbol Acetate | 1986 |
Promoting and anticarcinogenic effects of phenobarbital and DDT in the rat hepatocarcinogenesis.
Topics: Animals; Cocarcinogenesis; DDT; Drug Interactions; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; Mutagenicity Tests; Phenobarbital; Rats | 1986 |
o,p'-DDD in the mouse lung: selective uptake, covalent binding and effect on drug metabolism.
Topics: Adipose Tissue; Adrenal Glands; Aminopyrine; Animals; Autoradiography; Benzoflavones; beta-Naphthoflavone; DDT; Dose-Response Relationship, Drug; Isomerism; Liver; Lung; Maleates; Metyrapone; Mice; Mice, Inbred C57BL; Mitotane; Phenobarbital; Pulmonary Alveoli | 1986 |
Effect of in vivo exposure to the liver tumor promoters phenobarbital or DDT on the gap junctions of rat hepatocytes: a quantitative freeze-fracture analysis.
Topics: Animals; DDT; Freeze Fracturing; Intercellular Junctions; Liver; Liver Neoplasms; Male; Microscopy, Electron; Phenobarbital; Rats | 1987 |
Enzymatic detoxication of DDT to DDD by rat liver: effects of some inducers and inhibitors of cytochrome P-450 enzyme system.
Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DDT; Dichlorodiphenyldichloroethane; Enzyme Induction; Hydrogen-Ion Concentration; Inactivation, Metabolic; Liver; Methylcholanthrene; Phenobarbital; Rats; Temperature | 1987 |
Effects of phenobarbital, chlordane, and oxytetracycline on DDT excretion in rats.
Topics: Animals; Bile; Chlordan; DDT; Male; Oxytetracycline; Paralysis; Phenobarbital; Rats; Rats, Inbred Strains; Time Factors; Zoxazolamine | 1986 |
Effects of phenobarbital and p,p'-DDT on carboxylesterase activity and hydrolysis of propanidid in rat liver.
Topics: Animals; Carboxylic Ester Hydrolases; Cytochrome P-450 Enzyme System; Cytosol; DDT; Half-Life; Hydrolysis; Kinetics; Liver; Male; Microsomes, Liver; Phenobarbital; Propanidid; Rats; Rats, Inbred Strains; Time Factors | 1985 |
Effects of mixed-function oxidase modifiers on neurotoxicity of acrylamide in rats.
Topics: Acrylamide; Acrylamides; Animals; Cobalt; Cytochrome P-450 Enzyme System; DDT; Enzyme Induction; Male; Mixed Function Oxygenases; Nervous System; Paralysis; Phenobarbital; Rats; Rats, Inbred Strains | 1985 |
Effects of pretreatment with pyrazole and inducers of mixed function oxidases on DNA repair elicited by dimethylnitrosamine in rat hepatocytes in vivo and in vitro.
Topics: Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Cells, Cultured; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 CYP2E1; DDT; Diethylnitrosamine; Dimethylnitrosamine; DNA Repair; Enzyme Induction; Liver; Male; Methyl Methanesulfonate; Methylcholanthrene; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Phenobarbital; Pyrazoles; Rats; Rats, Inbred Strains | 1985 |
Comparative stimulation of HCH metabolism by pretreatment of rats with HCH, DDT, and DDT+ HCH.
Topics: Analysis of Variance; Aniline Compounds; Animals; Anisoles; Biotransformation; Carbon Isotopes; Cytochromes; DDT; Dealkylation; Feces; Female; Glucuronates; Hexachlorocyclohexane; Microsomes, Liver; Nitro Compounds; Phenobarbital; Rats; Stimulation, Chemical; Sulfates | 1971 |
Aryl hydrocarbon hydroxylase induction in mammalian liver cell culture. I. Stimulation of enzyme activity in nonhepatic cells and in hepatic cells by phenobarbital, polycyclic hydrocarbons, and 2,2-bis(p-chlorophenyl)-1,1,1-trichloroethane.
Topics: Animals; Benz(a)Anthracenes; Benzopyrenes; Carbon Isotopes; Cells, Cultured; Chick Embryo; Chromatography, Thin Layer; Cricetinae; DDT; Enzyme Induction; Extremities; Fetus; Gestational Age; Half-Life; Intestines; Kinetics; Liver; Lung; Methylcholanthrene; Mice; Mixed Function Oxygenases; Phenobarbital; Polycyclic Compounds; Protein Biosynthesis; Rabbits; Rats; RNA; Species Specificity; Time Factors; Tritium; Uridine | 1971 |
Axonal cholinergic binding macromolecule. Response to neuroactive drugs.
Topics: Action Potentials; Animals; Axonal Transport; Axons; Binding Sites; Binding, Competitive; DDT; Hemicholinium 3; Imidazoles; In Vitro Techniques; Ligands; Macromolecular Substances; Nephropidae; Nicotine; Ouabain; Parasympatholytics; Phenobarbital; Procaine; Receptors, Cholinergic; Tetraethylammonium Compounds; Tetrodotoxin; Toxins, Biological; Tritium; Veratrine | 1973 |
The toxicology of dieldrin (HEOD). II. Comparative long-term oral toxicity studies in mice with dieldrin, DDT, phenobarbitone, -BHC and -BHC.
Topics: Administration, Oral; Animals; DDT; Dieldrin; Female; Hepatomegaly; Hexachlorocyclohexane; Hyperplasia; Liver; Liver Neoplasms; Male; Mice; Microsomes, Liver; Mortality; Neoplasm Metastasis; Phenobarbital; Time Factors | 1973 |
[Influence of ethanol on the metabolism of drugs].
Topics: Aldrin; Animals; Benzopyrenes; Carcinogens; DDT; Drug Interactions; Ethanol; Histamine H1 Antagonists; Insecticides; Methylcholanthrene; Nikethamide; Pharmaceutical Preparations; Phenobarbital; Phenothiazines; Rats; Tolbutamide | 1969 |
Effect of barbiturates and isoniazid on cerebral hemisphere gamma-aminobutyric acid content in pp' DDT treated mice.
Topics: Aminobutyrates; Animals; Anticonvulsants; Barbiturates; Behavior, Animal; Brain Chemistry; DDT; Drug Synergism; gamma-Aminobutyric Acid; Isoniazid; Male; Mephobarbital; Mice; Phenobarbital; Primidone; Seizures | 1974 |
The effect of carcinogenic and noncarcinogenic compounds on the O-dealkylating activity of the hepatic microsomal enzyme system of the rat.
Topics: Animals; Biphenyl Compounds; Carcinogens; Cresols; DDT; Fluorescence; Hexachlorocyclohexane; Hydrocarbons; Imipramine; In Vitro Techniques; Liver; Male; Meprobamate; Microsomes; Phenobarbital; Rats | 1967 |
Treatment of unconjugated jaundice with dicophane.
Topics: Adolescent; Animals; Bilirubin; Cytochromes; DDT; Enzyme Induction; Glucuronates; Humans; Hyperbilirubinemia, Hereditary; Liver; Liver Cirrhosis; Male; Organ Size; Phenobarbital; Protein Binding; Proteins; Transferases | 1969 |
Effect of anticonvulsant drugs on dicophane (D.D.T.) residues in man.
Topics: Adipose Tissue; Child; Chromatography, Gas; DDT; Humans; Phenobarbital; Phenytoin | 1969 |
Phenobarbitone and dicophane in jaundice.
Topics: Animals; Bilirubin; DDT; Female; Humans; Infant, Newborn; Jaundice, Neonatal; Liver; Male; Maternal-Fetal Exchange; Phenobarbital; Pregnancy | 1969 |
Phenobarbitone and dicophane in jaundice.
Topics: DDT; Female; Humans; Infant, Newborn; Jaundice, Neonatal; Phenobarbital; Pregnancy | 1969 |
[Effect of DDT pretreatment of young ducks on eventual reaction towards a peanut oil-cake by aspergillus flavus].
Topics: Aflatoxins; Animals; Aspergillus flavus; Body Weight; DDT; Ducks; Liver; Male; Phenobarbital | 1974 |
[Changes in the endoplasmic reticulum caused by phenobarbital and DDT].
Topics: Animals; DDT; Endoplasmic Reticulum; Female; Liver; Microscopy, Electron; Phenobarbital; Rats | 1967 |
[Stimulation of several microsomal drug oxidations by phenobarbital, methylcholanthrene and chlorophenothane, single and in combinations].
Topics: Aniline Compounds; Animals; DDT; Drug Synergism; Female; Liver; Methylcholanthrene; Microsomes; Nitrobenzenes; Organ Size; Phenobarbital; Rats; Stimulation, Chemical | 1967 |
[Stimulation of drug oxidation in kidney microsomes by phenobarbital].
Topics: Aniline Compounds; Animals; Benzopyrenes; Cytochromes; DDT; Hexobarbital; Kidney; Liver; Male; Microsomes; Organ Size; Phenobarbital; Rabbits; Rats; Stimulation, Chemical | 1968 |
[Studies on microsomal hydroxylation of naphthalene].
Topics: Animals; Chromatography, Thin Layer; DDT; Enzyme Induction; Fluorometry; Kinetics; Liver; Mice; Microsomes; Mixed Function Oxygenases; Naphthalenes; Nitrophenols; Phenobarbital; Stimulation, Chemical | 1969 |
Liver enlargement and hepatoxicity: an investigation into the effects of several agents on rat liver enzyme activities.
Topics: Alanine Transaminase; Amides; Animals; Anticholesteremic Agents; Barbiturates; Body Weight; Butyrates; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; DDT; Glucose-6-Phosphatase; Glucose-6-Phosphate Isomerase; Glucosephosphate Dehydrogenase; Glutamate Dehydrogenase; Hepatomegaly; L-Lactate Dehydrogenase; Liver; Male; Phenobarbital; Phosphogluconate Dehydrogenase; Rats; Sulfhydryl Compounds | 1967 |
Phenobarbital and dexamethasone inhibition of the adrenocortical response of rats to toxic chemicals and other stresses.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldehydes; Animals; Brain; Cholinesterases; Cold Temperature; Corticosterone; DDT; Dexamethasone; Hindlimb; Liver; Male; Parathion; Phenobarbital; Rats; Stress, Physiological; Transaminases; Tryptophan Oxygenase | 1970 |
Effect of drugs and insecticides on the anesthetic action of steroids.
Topics: Androsterone; Anesthetics; Animals; Chlordan; DDT; Desoxycorticosterone; Histamine H1 Antagonists; Liver; Microsomes; Phenobarbital; Phenylbutazone; Progesterone; Rats | 1965 |
Decreased central depressant effect of progesterone and other steroids in rats pretreated with drugs and insecticides.
Topics: Animals; Brain; Chlordan; Chromatography, Paper; DDT; Histamine H1 Antagonists; In Vitro Techniques; Liver; Microsomes; Phenobarbital; Phenylbutazone; Piperazines; Progesterone; Rats | 1966 |
Magnetic and spectrophotometric properties of the microsomal carbon monoxide binding pigment.
Topics: Animals; Carbon Monoxide; Chlordan; Coloring Agents; Cytochromes; DDT; Diphenhydramine; Electron Spin Resonance Spectroscopy; Fasting; Ferrocyanides; Hydrogen-Ion Concentration; Liver; Microsomes; NAD; NADP; Oxygen; Phenobarbital; Phenytoin; Pigments, Biological; Rabbits; Rats; Spectrophotometry | 1967 |
The effect of diphenyl-piperazine compounds and other agents on diphenylhydantoin, zoxazolamine and hexobarbital metabolism.
Topics: Animals; Benzopyrenes; Cyclizine; DDT; Diphenhydramine; Endoplasmic Reticulum; Hexobarbital; Humans; Hydroxyzine; Liver; Male; Meclizine; Methylcholanthrene; Mice; Microscopy, Electron; Phenethylamines; Phenobarbital; Phenytoin; Piperazines; Trifluoperazine; Zoxazolamine | 1968 |
Some properties of the microsomal system metabolizing DDT in Triatoma infestans.
Topics: Animals; Chloromercuribenzoates; DDT; Depression, Chemical; Enzyme Induction; Hydrogen-Ion Concentration; Insecta; Kinetics; Magnesium; Microsomes; NAD; NADP; Niacinamide; Phenobarbital; Stimulation, Chemical; Sulfhydryl Compounds; Temperature; Time Factors; Triatominae | 1969 |
Influence of microsomal enzyme inducers on the reactivity of the isolated guinea pig seminal vesicle to angiotensin and tyramine.
Topics: Angiotensin II; Animals; Aspirin; Dactinomycin; DDT; Drug Antagonism; Enzyme Induction; Glutethimide; Guinea Pigs; Male; Meprobamate; Methylcholanthrene; Microsomes; Phenobarbital; Piperazines; Proadifen; Protein Biosynthesis; Seminal Vesicles; Sulfanilamides; Tyramine | 1969 |
Studies on the induction of nitroreductase activity by DDT and phenobarbital.
Topics: Aminobenzoates; Animals; Benzoates; Cyanides; DDT; Enzyme Induction; Liver; Male; Microsomes, Liver; NADP; Oxidoreductases; Phenobarbital; Proadifen; Rats; Sodium; Venoms | 1970 |
The conversion of pyrrolizidine alkaloids to N-oxides and to dihydropyrrolizine derivatives by rat-liver microsomes in vitro.
Topics: Alkaloids; Animals; Calcium; Carbon Monoxide; DDT; Diet; Kinetics; Lung; Magnesium; Manganese; Microsomes; Microsomes, Liver; Models, Biological; NADP; Niacinamide; Oxides; Oxygen; Phenobarbital; Proadifen; Proteins; Pyrroles; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains | 1971 |
A comparison of mouse and rat liver enzymes and their response to treatment with various compounds.
Topics: Aminopyrine; Animals; Carbon Tetrachloride; Chlorpromazine; Clofibrate; Cytochromes; DDT; Germ-Free Life; Glucose-6-Phosphatase; Glucosephosphate Dehydrogenase; Griseofulvin; L-Lactate Dehydrogenase; Liver; Mice; NAD; NADP; Organ Size; Oxidoreductases; Phenobarbital; Phosphogluconate Dehydrogenase; Rats; Species Specificity | 1972 |
Some studies and comments on hepatic and extrahepatic microsomal toxication-detoxication systems. A limited discussion of some of the heterogeneities of these systems and of their responses to stimulation of enzyme "induction".
Topics: Age Factors; Animals; Benzopyrenes; Cell Fractionation; Cytochromes; DDT; Enzyme Induction; Liver; Lung; Mice; Mice, Inbred Strains; Microsomes; Microsomes, Liver; NADH, NADPH Oxidoreductases; Pharmaceutical Preparations; Phenobarbital; Rabbits; Rats; Species Specificity; Stimulation, Chemical; Toxicology | 1972 |
The effect of prior treatment with phenobarbitone, dicophane (DDT) and beta-diethylaminoethyl phenylpropyl acetate (SKF 525A) on experimental intoxication of sheep with the plant Myoporum deserti Cunn.
Topics: Animals; Bilirubin; Biopsy; DDT; Edema; Eosinophils; Gallbladder; Gastrointestinal Hemorrhage; Ischemia; Kidney; Leukocytes; Liver; Male; Microsomes, Liver; Phenobarbital; Plant Extracts; Plant Poisoning; Premedication; Proadifen; Sesquiterpenes; Sheep; Sheep Diseases | 1973 |
Enzyme induction by polychlorinated biphenyls relative to known inducing agents.
Topics: Administration, Oral; Animal Feed; Animals; Cytochrome P-450 Enzyme System; DDT; Enzyme Induction; Hydroxylation; Liver; Male; Microsomes, Liver; Oxidation-Reduction; Phenobarbital; Polychlorinated Biphenyls; Proteins; Rats | 1972 |
Differences in microsomal enzyme induction between Sprague-Dawley and Long-Evans rats.
Topics: Aminopyrine; Aniline Compounds; Animals; Anisoles; Antipyrine; Brain Chemistry; DDT; Enzyme Induction; Eucalyptus; Female; Liver; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Phenols; Plant Extracts; Plants, Medicinal; Rats; Rats, Inbred Strains; Sleep | 1972 |
Effect of certain drugs and environmental agents on microsomal enzyme systems.
Topics: Aminopyrine N-Demethylase; Animals; Anisoles; Aspirin; Cytochrome P-450 Enzyme System; DDT; Enzyme Induction; Intestine, Small; Kidney; Lung; Male; Microsomes; Microsomes, Liver; Morphinans; Nitro Compounds; Oxidoreductases, N-Demethylating; Phenacetin; Phenanthrenes; Phenobarbital; Phenytoin; Rats; Transferases; Trifluoperazine | 1972 |
Demethylation of mestranol to ethinyloestradiol in vitro and in vivo.
Topics: Animals; Body Water; Carbon Isotopes; Chromatography; DDT; Ethinyl Estradiol; Female; Hydrogenation; In Vitro Techniques; Male; Mestranol; Methods; Methylation; Microsomes, Liver; Phenobarbital; Rats; Spirometry; Time Factors; Tritium | 1972 |
Modification of acrylamide neuropathy in rats by selected factors.
Topics: Acrylamides; Adrenal Glands; Adrenalectomy; Age Factors; Animals; DDT; Enzyme Induction; Hexobarbital; Hydrocortisone; In Vitro Techniques; Liver; Male; Microsomes, Liver; Motor Activity; Myelin Sheath; Neurons; Oxidoreductases; Peripheral Nerves; Phenobarbital; Proadifen; Rats; Thiamine Deficiency; Time Factors; Vitamin B 6 Deficiency | 1973 |
Stimulation of hepatic microsomal drug-metabolizing enzymes in mice by 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT) and 3,4-benzpyrene.
Topics: Aminopyrine N-Demethylase; Aniline Compounds; Animals; Benzopyrenes; Body Weight; Cytochrome P-450 Enzyme System; DDT; Dose-Response Relationship, Drug; Enzyme Induction; In Vitro Techniques; Liver; Male; Mice; Microsomes, Liver; Mixed Function Oxygenases; Organ Size; Phenobarbital; Rats; Species Specificity; Spectrophotometry; Stimulation, Chemical; Time Factors | 1973 |
Use of oral DDT in three human barbiturate intoxications: hepatic enzyme induction by reciprocal detoxicants.
Topics: Adolescent; Adult; Barbiturates; DDT; Drug Tolerance; Enzyme Induction; Female; Humans; Liver; Pentobarbital; Phenobarbital; Secobarbital | 1973 |
The impact of changing pesticide usage on the medical community.
Topics: Antidotes; Atropine; Child; DDT; Humans; Pesticides; Phenobarbital; Pralidoxime Compounds; Respiration, Artificial | 1973 |
Effect of phenobarbital sodium on the uterotropic action of o.p'-DDT.
Topics: Animals; Castration; DDT; Diaphragm; Female; In Vitro Techniques; Liver; Microsomes; Organ Size; Phenobarbital; Proteins; Rats; Spleen; Time Factors; Uterus; Water | 1973 |
The effect of carbon disulphide used in combination with carbon tetrachloride on the toxicity of the latter drug for sheep.
Topics: Aminopyrine; Animals; Biopsy; Carbon Disulfide; Carbon Radioisotopes; Carbon Tetrachloride; DDT; Diet; Drug Combinations; Fasciola hepatica; Liver; Male; Microsomes, Liver; Phenobarbital; Proadifen; Sheep | 1973 |
Influence of sex hormones on vitamin K deficiency and epoxidation of vitamin K in the rat.
Topics: Animals; Carbon Radioisotopes; Castration; DDT; Estradiol; Ethers, Cyclic; Female; Gonadal Steroid Hormones; Hydrolases; Male; Methylcholanthrene; Microsomes, Liver; Oxidoreductases; Phenobarbital; Progesterone; Prothrombin; Rats; Sex Factors; Testosterone; Time Factors; Vitamin K 1; Vitamin K Deficiency | 1974 |
Enhancement of D-glucuronolactone and acetaldehyde dehydrogenase activities in the rat liver by inducers of drug metabolism.
Topics: Acetaldehyde; Alcohol Oxidoreductases; Aldehyde Oxidoreductases; Animals; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; DDT; Enzyme Induction; Germ-Free Life; Hydrogen-Ion Concentration; Lactones; Liver; Male; Methylcholanthrene; Oils; Organ Size; Phenobarbital; Proteins; Pyrazoles; Rats; Spironolactone | 1974 |
Stimulation of hepatic drug-metabolizing enzymes by DDT, polycyclic hydrocarbons or phenobarbital in adrenalectomized or castrated mice.
Topics: Adrenal Glands; Adrenalectomy; Aminopyrine N-Demethylase; Aniline Compounds; Animals; Benzopyrenes; Benzphetamine; Castration; DDT; Dealkylation; Hydrogen-Ion Concentration; Liver; Male; Methylcholanthrene; Methyltransferases; Mice; Mixed Function Oxygenases; Morphinans; Phenobarbital; Polycyclic Compounds; Proteins; Stimulation, Chemical; Testis | 1974 |
Interaction of environmental agents and drugs.
Topics: Animals; Anticoagulants; Antipyrine; Benzopyrenes; Chlordan; DDT; Dogs; Environment; Environmental Exposure; Enzyme Induction; Haplorhini; Humans; Male; Microsomes, Liver; Pharmaceutical Preparations; Pharmacology; Phenobarbital; Phenylbutazone; Rats; Toxicology; Zoxazolamine | 1969 |
Bilirubin: a model for studies of drug metabolism in man.
Topics: Acetamides; Allyl Compounds; Amino Sugars; Amphibians; Animals; Anura; Bilirubin; Birds; Butyrophenones; Carbon Isotopes; Cats; Cell Nucleus; Chromatography, Gel; Cyclohexanes; DDT; Dieldrin; Fishes; Glucose; Goats; Guinea Pigs; Haplorhini; Humans; Iodobenzenes; Kinetics; Liver; Lysosomes; Mammals; Methylcholanthrene; Mice; Microsomes, Liver; Mitochondria, Liver; Organ Specificity; Phenobarbital; Protein Binding; Protein Biosynthesis; Rats | 1971 |
The effect of diet and drugs on hepatic microsomal aminopyrine N-demethylase activity in vitro and susceptibility to carbon tetrachloride in sheep.
Topics: Aminopyrine; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; DDT; Diet; Dietary Proteins; Food Deprivation; Freezing; Liver; Male; Microsomes, Liver; Oxidoreductases; Phenobarbital; Sheep; Sheep Diseases; Water Deprivation | 1972 |
Acute toxicity and antiesterase action of O-ethyl-S,S-diphenyl phosphorodithioate (Hinosan).
Topics: Animals; Atropine; Benzene Derivatives; Brain; Cholinesterase Inhibitors; Cholinesterases; DDT; Drug Interactions; Drug Resistance; Drug Synergism; Female; Fungicides, Industrial; Injections, Intraperitoneal; Insecticides; Lethal Dose 50; Malathion; Male; Methylcholanthrene; Organothiophosphorus Compounds; Phenobarbital; Pralidoxime Compounds; Rats; Submandibular Gland; Testosterone; Time Factors | 1972 |
Effect of microsomal enzyme inducing drugs on DDt and dieldrin elimination from cows.
Topics: Animals; Cattle; Cattle Diseases; DDT; Dieldrin; Diet Therapy; Enzymes; Fats; Microsomes, Liver; Milk; Pesticides; Phenobarbital; Phenytoin; Poisoning | 1971 |
Studies of Y and Z, two hepatic cytoplasmic organic anion-binding proteins: effect of drugs, chemicals, hormones, and cholestasis.
Topics: Allyl Compounds; Animals; Benzopyrenes; Cholestasis; DDT; Densitometry; Dieldrin; Dwarfism, Pituitary; Electrophoresis, Disc; Ethinyl Estradiol; Hypophysectomy; Indocyanine Green; Liver; Male; Methylcholanthrene; Phenobarbital; Protein Binding; Proteins; Rats; Sulfobromophthalein; Thyroid Hormones; Thyroidectomy | 1971 |
The effects of some stimulators (inducers) of hepatic microsomal drug-metabolizing enzyme activity on substrate-induced difference spectra in rat liver microsomes.
Topics: Aniline Compounds; Animals; Benzphetamine; Carbon Isotopes; DDT; Enzyme Induction; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Phenytoin; Rats; Spectrophotometry | 1971 |
Removal of pesticide residues from dairy cattle.
Topics: Aluminum Silicates; Animals; Antidotes; Calcium; Carbon; Cattle; Cattle Diseases; DDT; Dieldrin; Fats; Hydrocarbons, Halogenated; Oils; Pesticides; Phenobarbital; Poisoning; Proteins; Quinolines; Vitamin A; Vitamin D; Vitamin E | 1971 |
Anticonvulsants and DDT residues.
Topics: Adult; DDT; Environmental Exposure; Humans; Hydrocarbons, Halogenated; Male; Phenobarbital; Phenytoin | 1971 |
Aminopyrine demethylase--multiplicity shown by dieldrin and DDT inhibition.
Topics: Aminopyrine; Animals; DDT; Dealkylation; Dieldrin; Enzyme Induction; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Oxidoreductases; Phenobarbital; Rats; Stimulation, Chemical | 1971 |
[Induction of liver microsomal enzymes and its significance in the treatment of jaundice].
Topics: Animals; Bile Pigments; Bilirubin; Biotransformation; DDT; Enzyme Induction; Humans; Jaundice; Microsomes, Liver; Phenobarbital; Stimulation, Chemical | 1971 |
Effect of inducers of drug-metabolizing enzymes on diethylnitrosamine metabolism and toxicity.
Topics: Animals; DDT; Enzyme Induction; Female; Methylcholanthrene; Microsomes, Liver; Nitrosamines; Phenobarbital; Rats; Toluene | 1971 |
A possible role of liver microsomal alkaline ribonuclease in the stimulation of oxidative drug metabolism by phenobarbital, chlordane and chlorophenothane (DDT).
Topics: Aminopyrine; Aniline Compounds; Animals; Chlordan; Cytochromes; DDT; Male; Microsomes, Liver; Mixed Function Oxygenases; Organ Size; Oxidoreductases; Oxygen Consumption; Phenobarbital; Rats; Rats, Inbred Strains; Ribonucleases | 1971 |
Determinants of toxicity.
Topics: Animals; Animals, Newborn; Binding Sites; Carbon Tetrachloride Poisoning; Cell Differentiation; Cytochromes; DDT; Dietary Proteins; Enzyme Induction; Genetics; Humans; Lethal Dose 50; Microsomes, Liver; Phenobarbital; Rats; Sheep; Toxicology | 1971 |
Modification of catecholamine content of male accessory sexual tissues of guinea pig after pretreatment with microsomal enzyme inducers.
Topics: Adrenal Glands; Animals; Brain; Castration; Catecholamines; Dactinomycin; DDT; Epinephrine; Guinea Pigs; Male; Methylcholanthrene; Norepinephrine; Pargyline; Phenobarbital; Proteins; Seminal Vesicles; Testis; Vas Deferens | 1971 |
Inductive effects of 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane(DDT), phenobarbital, and benzpyrene on microsomal cytochrome B450, ethyl isocyanide spectra, and metabolism in vivo of zoxazolamine and hexobarbital in the mouse.
Topics: Animals; Benzopyrenes; Cyanides; Cytochrome P-450 Enzyme System; DDT; Enzyme Induction; Hexobarbital; Male; Mice; Microsomes, Liver; Paralysis; Phenobarbital; Proteins; Sleep; Spectrum Analysis; Time Factors; Zoxazolamine | 1971 |
The effect of protein deficiency and microsomal enzyme induction by DDT and phenobarbitone on the acute toxicity of chloroform and a pyrrolizidine alkaloid, retrorsine.
Topics: Alkaloids; Animals; Carbon Tetrachloride; Chloroform; DDT; Enzyme Induction; Heterocyclic Compounds; Liver; Male; Microsomes; Phenobarbital; Protein Deficiency; Rats | 1970 |
Effect of parathion on liver microsomal enzyme activites induced by organochlorine pesticides and drugs in female rats.
Topics: Animals; Azo Compounds; Chlordan; DDT; Dimenhydrinate; Female; Hydrocarbons, Halogenated; Microsomes, Liver; Naphthalenes; Oxidoreductases; Paraldehyde; Parathion; Phenobarbital; Phenytoin; Rats; Trimethadione | 1970 |
Enzyme induction: introduction.
Topics: Alkaline Phosphatase; Animals; Biliary Tract Diseases; Binding Sites; DDT; Enzyme Induction; Humans; Hyperbilirubinemia; Infant, Newborn; Phenobarbital; Porphyrins | 1970 |
Relations between barbiturate brain levels and sleeping time in various experimental conditions.
Topics: Amphetamine; Animals; Brain Chemistry; Chlorpromazine; DDT; Dextroamphetamine; Diazepam; Female; Pentobarbital; Phenobarbital; Proadifen; Rats; Sleep; Time Factors | 1970 |
[Physiopathology and treatment of icterus neonatorum. Prospects opened by enzymatic induction].
Topics: Bilirubin; DDT; Enzyme Induction; Erythroblastosis, Fetal; Ethanol; Female; Humans; Infant, Newborn; Nikethamide; Phenobarbital; Pregnancy | 1970 |
Drug and environmental effects on DDT residues in human blood.
Topics: Adult; DDT; Environment; Female; Humans; Intellectual Disability; Male; Phenobarbital; Phenytoin; Racial Groups | 1970 |
Increased renal carcinogenesis by dimethyl nitrosamine in protein deficient rats.
Topics: Animals; DDT; Enzyme Induction; Kidney Neoplasms; Male; Microsomes, Liver; Neoplasms, Experimental; Nitrosamines; Phenobarbital; Protein Deficiency; Rats | 1970 |
[The lung and massive intentional poisoning by organo-phosphoric substances].
Topics: Adolescent; Adult; DDT; Female; Humans; Insecticides; Lung; Lung Diseases; Male; Parasympatholytics; Parathion; Phenobarbital; Phosphoric Acids; Pralidoxime Compounds; Respiratory Insufficiency; Resuscitation; Suicide; Tropanes | 1970 |
Diphenylhydantoin-induced difference spectra with rat-liver microsomes.
Topics: Animals; Benzphetamine; Chlordan; DDT; Drug Interactions; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Spectrum Analysis | 1970 |
Drugs and the liver.
Topics: Bilirubin; Cushing Syndrome; DDT; Enzyme Induction; Ethanol; Female; Humans; Hyperbilirubinemia; Infant, Newborn; Jaundice, Neonatal; Liver; Male; Phenobarbital; Phenytoin; Porphyrins; Pregnancy; Transferases; Warfarin | 1970 |
Microsomal hydroxylase induction in liver cell culture by phenobarbital, polycyclic hydrocarbons, and p,p'-DDT.
Topics: Animals; Benz(a)Anthracenes; DDT; Enzyme Induction; Fetus; In Vitro Techniques; Liver; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Models, Biological; Phenobarbital; Rats | 1971 |
Toxicity of carbon tetrachloride and other fasciocidal drugs in sheep and chickens.
Topics: Administration, Oral; Alcohol Oxidoreductases; Animals; Anthelmintics; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chickens; DDT; Fascioliasis; Female; Glutamate Dehydrogenase; Hydrocarbons, Halogenated; Injections, Intraperitoneal; Kidney; Lethal Dose 50; Liver; Male; Muscles; Nitriles; Nitrophenols; Ornithine Carbamoyltransferase; Peritonitis; Phenobarbital; Sheep; Sorbitol | 1971 |
Effect of phenobarbital pretreatment on the metabolism of DDT in the rat and the bovine.
Topics: Acetates; Animals; Biotransformation; Cattle; DDT; Dichlorodiphenyldichloroethane; Female; Hydrocarbons, Halogenated; Liver; Milk; Nitrophenols; Parathion; Phenobarbital; Phosphoric Acids; Rats; Stimulation, Chemical | 1971 |
Diphenylhydantoin metabolism by rat liver microsomes and some of the effects of drug or chemical pretreatment on diphenylhydantoin metabolism by rat liver microsomal preparations.
Topics: Animals; Chlordan; DDT; Enzyme Induction; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Phenytoin; Rats; Spectrophotometry; Stimulation, Chemical | 1971 |
Subcellular localization and drug-induced changes of rat liver and kidney esterases.
Topics: Animals; DDT; Electrophoresis; Endoplasmic Reticulum; Esterases; Gels; Histocytochemistry; Kidney; Liver; Male; Microscopy, Electron; Microsomes; Mitochondria, Liver; Phenobarbital; Rats; Starch | 1968 |
Stimulatory effect of phenobarbital and insecticides on warfarin metabolism in the rat.
Topics: Animals; Carbon Isotopes; Chlordan; Chromatography, Thin Layer; DDT; Liver; Male; Mixed Function Oxygenases; Phenobarbital; Rats; Stimulation, Chemical; Warfarin | 1968 |
The effect of a pretreatment with phenobarbital on the metabolism of DDT in dairy cows and young bulls.
Topics: Animals; Cattle; DDT; Female; Male; Milk; Phenobarbital | 1968 |
Induction of microsomal hydroxylase: involvement of a second factor besides cytochrome P-450.
Topics: Aniline Compounds; Animals; Benzopyrenes; Cytochromes; DDT; Enzyme Induction; Female; Formaldehyde; Hexobarbital; Male; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Rats | 1968 |
Effects of diet and microsomal enzyme induction on the toxicity of dimethyl nitrosamine.
Topics: Animals; DDT; Diet; Dietary Proteins; Enzyme Induction; Liver; Microsomes; Nitrosamines; Phenobarbital; Rats; Starvation | 1969 |
DDT-induced metabolic changes in rat liver.
Topics: Animals; Carbon Isotopes; Cell-Free System; DDT; Enzyme Induction; Glutathione; Hydrocortisone; Leucine; Liver; Lyases; Male; Microsomes; Organ Size; Oxidation-Reduction; Phenobarbital; Protein Biosynthesis; Rats; RNA; Stimulation, Chemical | 1967 |
Dose-response studies on promoting and anticarcinogenic effects of phenobarbital and DDT in the rat hepatocarcinogenesis.
Topics: Animals; DDT; Dose-Response Relationship, Drug; Liver; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; Phenobarbital; Rats; Rats, Inbred Strains | 1984 |
The effects of twenty-two organochlorine pesticides as inducers of the hepatic drug-metabolizing enzymes.
Topics: Animals; Cyclohexanes; DDT; Enzyme Induction; Hexachlorobenzene; Insecticides; Liver; Male; Methylcholanthrene; Pharmaceutical Preparations; Phenobarbital; Rats; Toxaphene | 1983 |
Carcinogenic effects induced in Wistar rats by combined treatment with technical-grade dichlorodiphenyltrichloroethane and sodium phenobarbital.
Topics: Animals; Body Weight; Cocarcinogenesis; DDT; Diet; Female; Liver Neoplasms, Experimental; Male; Phenobarbital; Rats; Rats, Inbred Strains; Sex Factors; Time Factors | 1983 |
Differential induction of rat liver microsomal UDP-glucuronosyltransferase activites by various inducing agents.
Topics: Animals; Aroclors; Benzoflavones; Benzopyrene Hydroxylase; Benzopyrenes; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Clofibric Acid; DDT; Enzyme Induction; Glucuronosyltransferase; Male; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Stilbenes | 1982 |
Effects of DDT and dieldrin on intestinal glucose transport and brush border hydrolases. A comparison with phenobarbital and methylcholanthrene.
Topics: Animals; Biological Transport; DDT; Dieldrin; Enzyme Induction; Glucose; Hydrolases; Intestinal Absorption; Intestinal Mucosa; Male; Methylcholanthrene; Mice; Microvilli; Phenobarbital | 1983 |
Decreased levels of S-adenosylmethionine in the livers of rats fed phenobarbital and DDT.
Topics: Animals; Body Weight; Choline; DDT; Diet; Eating; Liver; Male; Methionine; Organ Size; Phenobarbital; Rats; Rats, Inbred F344; S-Adenosylmethionine | 1982 |
A possible neurochemical basis of the central stimulatory effects of pp'DDT.
Topics: Acetylcholine; Aminooxyacetic Acid; Ammonia; Animals; Central Nervous System; Corpus Striatum; DDT; gamma-Aminobutyric Acid; Hydroxylamines; Male; Mephobarbital; Mice; Phenobarbital; Primidone; Pyridoxine; Seizures | 1981 |
[Inhibition and acceleration of the metabolism of enflurane and methoxyflurane in rats (author's transl)].
Topics: Animals; DDT; Dimethyl Sulfoxide; Drug Interactions; Enflurane; Ethanol; Half-Life; Male; Maleates; Methoxyflurane; Phenobarbital; Rats; Rifampin | 1981 |
Phenobarbital treatments lower DDT body burden in rhesus monkeys.
Topics: Animals; Body Burden; DDT; Dichlorodiphenyl Dichloroethylene; Dichlorodiphenyldichloroethane; Enzyme Induction; Liver; Macaca mulatta; Male; Phenobarbital | 1981 |
[Effect of inducers of mixed-function microsomal oxidases on the immune response of mice induced by heterologous erythrocytes].
Topics: Animals; Anti-Anxiety Agents; Antibody Formation; Benzodiazepines; Benzodiazepinones; Cytochrome P-450 Enzyme System; DDT; Diazepam; Enzyme Induction; Erythrocytes; Male; Methylcholanthrene; Mice; Phenobarbital; Phenytoin; Rifampin; Sheep | 1981 |
Difference in the nature of induction of mixed-function oxidase systems of the rat liver among phenobarbital, DDT, 3-methylcholanthrene, and TCDD.
Topics: Animals; DDT; Enzyme Induction; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Polychlorinated Dibenzodioxins; Rats; Rats, Inbred Strains | 1981 |
Inhibition of intercellular communication in rat hepatocytes by phenobarbital, 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT) and gamma-hexachlorocyclohexane (lindane): modification by antioxidants and inhibitors of cyclo-oxygenase.
Topics: Animals; Antioxidants; Arachidonic Acid; Aspirin; Carcinogens; Cell Communication; Cells, Cultured; Cyclooxygenase Inhibitors; DDT; Hexachlorocyclohexane; Intercellular Junctions; Liver; Male; Phenobarbital; Rats; Rats, Wistar; Superoxide Dismutase; Vitamin E | 1993 |
Putative role of antioxidant enzymes and glyoxalases in carcinogenesis.
Topics: Animals; DDT; Depression, Chemical; Estradiol; Female; Lactoylglutathione Lyase; Liver; Neoplasms, Experimental; Oxidoreductases; Phenobarbital; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Thiolester Hydrolases | 1993 |
The use of initiated cells as a test system for the detection of inhibitors of gap junctional intercellular communication.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aroclors; Benzoyl Peroxide; Biotransformation; Calcium; Carcinogens; Cell Communication; Cell Differentiation; Cell Line; Cyclohexenes; DDT; Intercellular Junctions; Keratinocytes; Limonene; Mice; Phenobarbital; Rats; Terpenes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Alteration of intercellular communication in a human urothelial carcinoma cell-line by tumor-promoting agents.
Topics: Adult; Anticonvulsants; Antioxidants; Butylated Hydroxyanisole; Carcinogens; Carcinoma, Transitional Cell; Cell Communication; Clone Cells; Cyclamates; DDT; Dose-Response Relationship, Drug; Humans; Male; Phenobarbital; Saccharin; Tryptophan; Tumor Cells, Cultured; Urinary Bladder Neoplasms; Urothelium | 1996 |
The chemopreventive agent diallyl sulfide. A structurally atypical phenobarbital-type inducer.
Topics: Allyl Compounds; Animals; Antioxidants; Base Sequence; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DDT; Enzyme Induction; Glutathione Transferase; Liver; Male; Molecular Sequence Data; Phenobarbital; Rats; Rats, Inbred F344; Structure-Activity Relationship; Sulfides; Transcription, Genetic | 1995 |
Inducibility of the Drosophila melanogaster cytochrome P450 gene, CYP6A2, by phenobarbital in insecticide susceptible or resistant strains.
Topics: Animals; Blotting, Northern; Blotting, Southern; Cytochrome P-450 Enzyme System; DDT; Drosophila melanogaster; Gene Expression; Insecticide Resistance; Phenobarbital | 1996 |
Downregulation of intracellular cyclic AMP levels by tumour promoting agents.
Topics: Animals; Carcinogens; Cell Line; Cyclic AMP; DDT; Dogs; Epithelium; Kidney; Kinetics; Phenobarbital; Swine; Tetradecanoylphorbol Acetate | 1997 |
Mixed function oxidase system in hepatic and extrahepatic tissues of developing chickens following various treatments.
Topics: Animals; Chickens; DDT; Hypnotics and Sedatives; Insecticides; Liver; Mixed Function Oxygenases; Phenobarbital | 1995 |
[The effect of permethrin and DDT on the activity of cytochrome P-450 1A and 2B molecular forms in rat liver].
Topics: Animals; Cytochrome P-450 Enzyme System; DDT; Dose-Response Relationship, Drug; Insecticides; Liver; Male; Organ Size; Permethrin; Phenobarbital; Pyrethrins; Rats; Rats, Wistar | 1997 |
Inhibition of gap junctional intercellular communication by tumor promoters in connexin43 and connexin32-expressing liver cells: cell specificity and role of protein kinase C.
Topics: Animals; Carcinogens; Cell Communication; Cells, Cultured; Connexin 43; Connexins; DDT; Enzyme Activation; Gap Junction beta-1 Protein; Gap Junctions; Liver; Phenobarbital; Protein Kinase C; Rats; Rats, Inbred F344; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1998 |
Inhibition of transforming growth factor beta1-induced hepatoma cell apoptosis by liver tumor promoters: characterization of primary signaling events and effects on CPP32-like caspase activity.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Calcium-Calmodulin-Dependent Protein Kinases; Caspase 3; Caspases; Clofibrate; DDT; Dexamethasone; Dieldrin; Insulin; Liver Neoplasms, Experimental; NF-kappa B; Phenobarbital; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats; Signal Transduction; Time Factors; Transforming Growth Factor beta; Tumor Cells, Cultured | 1999 |
Activation of cytochrome P450 gene expression in the rat brain by phenobarbital-like inducers.
Topics: Allyl Compounds; Amitriptyline; Animals; Aryl Hydrocarbon Hydroxylases; Blotting, Northern; Brain; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; DDT; Enzyme Induction; Epoxide Hydrolases; Liver; Male; Mixed Function Oxygenases; Phenobarbital; Phenytoin; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Steroid Hydroxylases; Stilbenes; Sulfides | 2000 |
Stimulation of DNA synthesis by tumor promoters in primary rat hepatocytes is not mediated by arachidonic acid metabolites.
Topics: Animals; Arachidonic Acid; Carcinogens; Cell Division; Cells, Cultured; DDT; Dinoprostone; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hepatocytes; Hexachlorocyclohexane; Hypnotics and Sedatives; Male; Phenobarbital; Pregnenolone Carbonitrile; Prostaglandins; Rats; Rats, Wistar; Tritium | 2001 |
CHLORINATED HYDROCARBON INSECTICIDES. INTOXICATION AND GUIDE TO TREATMENT.
Topics: Antidotes; Calcium; Chlordan; DDT; Diagnosis; Dieldrin; Emetics; Gastric Lavage; Gluconates; Humans; Hydrocarbons, Chlorinated; Insecticides; Pentobarbital; Phenobarbital; Poisoning; Respiration; Respiration, Artificial; Sodium Chloride; Therapeutics; Toxicology | 1964 |
The DHR96 nuclear receptor regulates xenobiotic responses in Drosophila.
Topics: Animals; DDT; DNA-Binding Proteins; Drosophila; Drosophila Proteins; Gene Expression Regulation; Mutation; Phenobarbital; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Transcription, Genetic; Xenobiotics | 2006 |
Functional analysis of the cis-acting elements responsible for the induction of the Cyp6a8 and Cyp6g1 genes of Drosophila melanogaster by DDT, phenobarbital and caffeine.
Topics: Animals; Caffeine; Cell Line; Cytochrome P-450 Enzyme System; DDT; Drosophila melanogaster; Drosophila Proteins; Drug Synergism; Gene Expression Regulation; Insecticide Resistance; Luciferases; Phenobarbital; Regulatory Elements, Transcriptional; Sequence Analysis, DNA; Xenobiotics | 2010 |