Page last updated: 2024-08-22

ddms and 20-hydroxy-5,8,11,14-eicosatetraenoic acid

ddms has been researched along with 20-hydroxy-5,8,11,14-eicosatetraenoic acid in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (2.70)18.2507
2000's34 (91.89)29.6817
2010's2 (5.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alonso-Galicia, M; Harder, DR; Hudetz, AG; Roman, RJ; Shen, H1
Falck, JR; Frisbee, JC; Lombard, JH1
Baum, M; Falck, JR; Griener, JC; Quigley, R; Reddy, KM1
Falck, JR; Frisbee, JC; Linderman, JR; Lombard, JH; Roman, RJ1
Birks, EK; Campbell, WB; Falck, JR; Gebremedhin, D; Harder, DR; Hudetz, AG; Lange, AR; Lowry, TF; Narayanan, J; Nithipatikom, K; Okamoto, H; Roman, RJ; Taheri, MR1
Birks, EK; Dawson, CA; Falck, JR; Jacobs, ER; Patel, M; Presberg, K; Roman, RJ; Zhu, D1
Falck, JR; Frisbee, JC; Krishna, UM; Lombard, JH; Roman, RJ2
Balazy, M; Gu, R; Jiang, H; Wang, W; Wei, Y1
Alonso-Galicia, M; Falck, JR; Kunert, MP; Lombard, JH; Roman, RJ1
Falck, JR; Gu, RM; Krishna, UM; Wang, WH; Wei, Y1
Bondlela, M; Falck, JR; Imig, JD; Inscho, EW; Zhao, X1
Falck, JR; Krishna, UM; Laniado-Schwartzman, M; Nasjletti, A; Wang, MH; Zhang, F1
Alonso-Galicia, M; Cowley, AW; Greene, AS; Maier, KG; Roman, RJ1
Gu, RM; Wang, WH1
Falck, JR; Gisolfi, CV; Krishna, UM; Looft-Wilson, RC1
Falck, JR; Gopal, VR; Kaide, J; Laniado-Schwartzman, M; Nasjletti, A; Wang, JS; Wang, MH; Zhang, F1
Falck, JR; Gopal, VR; Laniado-Schwartzman, M; Nasjletti, A; Wang, JS; Wang, MH; Zand, B; Zhang, F1
Falck, JR; Gopal, VR; Imig, JD; Inscho, EW; Zhao, X1
Campbell, WB; Endsley, MP; Falck, JR; Gross, ER; Gross, GJ; Isbell, MA; Moore, JM; Nithipatikom, K1
Deng, H; Falck, JR; Gopal, VR; Kemp, R; Laniado-Schwartzman, M; Nasjletti, A; Singh, H; Zhang, F1
de la Cruz, L; Falck, JR; Lombard, JH; Roman, RJ; Wang, J1
Busse, R; Falck, JR; Fleming, I; Kiss, L; Randriamboavonjy, V1
Chen, P; Edwards, PA; Falck, JR; Guo, M; Roman, RJ; Scicli, AG; Wygle, D1
Brandes, RP; Busse, R; Fleming, I; Hammock, BD; Jung, O; Kim, IH; Schmidt, R; Schweda, F1
Abman, SH; Falck, JR; Grover, TR; Kinsella, JP; Parker, TA1
Capdevila, JH; Falck, JR; Lavrentyev, EN; Malik, KU; Parmentier, JH1
Brands, MW; Chang, HH; Du, J; Falck, JR; Huang, H; Raju, VT; Wang, CY; Wang, MH; Zhou, Y1
Falck, JR; Huang, A; Kaley, G; Sun, D; Yan, C1
Campbell, WB; Endsley, MP; Falck, JR; Gross, GJ; Isbell, MA; Moore, JM; Nithipatikom, K1
Falck, JR; Gross, GJ; Isbell, MA; Moore, JM; Nithipatikom, K1
Gruenloh, S; Jacobs, ER; Lopez, B; Medhora, M; Zhu, D1
Berezan, DJ; Davidge, ST; Dunn, KM; Falck, JR1
Ao, Y; Cheng, H; Li, Y; Lv, X; Peng, R; Wan, J; Yang, J1
Falck, JR; Friesma, J; Kunert, MP; Lombard, JH1
Certíková Chábová, V; Cervenka, L; Falck, JR; Hammock, BD; Imig, JD; Kompanowska-Jezierska, E; Kopkan, L; Kramer, HJ; Kujal, P; Sadowski, J; Vanecková, I; Vanourková, Z; Vernerová, Z; Walkowska, A1
Anjaiah, S; Falck, JR; Lombard, JH; Raffai, G; Roman, RJ; Wang, J; Weinberg, B1

Other Studies

37 other study(ies) available for ddms and 20-hydroxy-5,8,11,14-eicosatetraenoic acid

ArticleYear
Contribution of 20-HETE to vasodilator actions of nitric oxide in the cerebral microcirculation.
    Stroke, 1999, Volume: 30, Issue:12

    Topics: Adenosine; Alkaloids; Amides; Animals; Basilar Artery; Carbazoles; Cerebrovascular Circulation; Cyclic GMP; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Hydrazines; Hydroxyeicosatetraenoic Acids; Indoles; Male; Microcirculation; Middle Cerebral Artery; Mixed Function Oxygenases; Nitric Oxide; Nitroprusside; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Sulfones; Vasodilation; Vasodilator Agents

1999
Contribution of cytochrome P-450 omega-hydroxylase to altered arteriolar reactivity with high-salt diet and hypertension.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 278, Issue:5

    Topics: Acetylcholine; Amides; Angiotensin II; Animals; Arterioles; Blood Pressure; Cardiovascular Agents; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; Hypertension, Renal; Male; Microscopy, Video; Mixed Function Oxygenases; Muscle, Skeletal; Nitroprusside; Oxygen; Perfusion; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Sulfones

2000
Effects of 20-HETE and 19(S)-HETE on rabbit proximal straight tubule volume transport.
    American journal of physiology. Renal physiology, 2000, Volume: 278, Issue:6

    Topics: Amides; Animals; Arachidonic Acid; Biological Transport, Active; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Kidney Tubules, Proximal; Mixed Function Oxygenases; Perfusion; Rabbits; Sodium-Potassium-Exchanging ATPase; Sulfones

2000
Impairment of flow-induced dilation of skeletal muscle arterioles with elevated oxygen in normotensive and hypertensive rats.
    Microvascular research, 2000, Volume: 60, Issue:1

    Topics: Amides; Animals; Arterioles; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Hemorheology; Hydroxyeicosatetraenoic Acids; Hypertension; Male; Microcirculation; Microscopy, Video; Mixed Function Oxygenases; Muscle, Skeletal; Oxygen; Partial Pressure; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sulfones; Vasodilation

2000
Production of 20-HETE and its role in autoregulation of cerebral blood flow.
    Circulation research, 2000, Jul-07, Volume: 87, Issue:1

    Topics: Amides; Animals; Cerebral Arteries; Cerebrovascular Circulation; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Homeostasis; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Microsomes; Mixed Function Oxygenases; Muscle, Smooth, Vascular; Rats; RNA, Messenger; Sulfones; Vasoconstriction

2000
Hypoxic pulmonary vasoconstriction is modified by P-450 metabolites.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:4

    Topics: Amides; Animals; Caproates; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Female; Hydroxyeicosatetraenoic Acids; Hypoxia; In Vitro Techniques; Male; Mixed Function Oxygenases; Phenylephrine; Pulmonary Artery; Pulmonary Circulation; Rabbits; Sulfones; Vasoconstriction; Vasoconstrictor Agents

2000
20-HETE modulates myogenic response of skeletal muscle resistance arteries from hypertensive Dahl-SS rats.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:3

    Topics: Amides; Animals; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Hydroxyeicosatetraenoic Acids; Male; Mixed Function Oxygenases; Muscle, Skeletal; Muscle, Smooth, Vascular; Potassium Channels; Rats; Rats, Inbred Dahl; Sulfones; Vascular Resistance; Vasoconstriction

2001
Role of 20-HETE in mediating the effect of dietary K intake on the apical K channels in the mTAL.
    American journal of physiology. Renal physiology, 2001, Volume: 280, Issue:2

    Topics: Amides; Animals; Enzyme Inhibitors; Hydroxyeicosatetraenoic Acids; Kidney Tubules; Potassium Channels; Potassium, Dietary; Rats; Rats, Sprague-Dawley; Sulfones

2001
Cytochrome P-450 omega-hydroxylase: a potential O(2) sensor in rat arterioles and skeletal muscle cells.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:4

    Topics: Amides; Animals; Arterioles; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; Kidney; Liver; Male; Mixed Function Oxygenases; Muscle, Skeletal; Oxygen; Rats; Rats, Sprague-Dawley; Sulfones; Vasoconstriction

2001
20-HETE contributes to myogenic activation of skeletal muscle resistance arteries in Brown Norway and Sprague-Dawley rats.
    Microcirculation (New York, N.Y. : 1994), 2001, Volume: 8, Issue:1

    Topics: Amides; Animals; Arteries; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Endothelium, Vascular; Enzyme Inhibitors; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Male; Mixed Function Oxygenases; Muscle, Skeletal; Potassium Channel Blockers; Rats; Rats, Inbred BN; Rats, Sprague-Dawley; Sulfones; Vascular Resistance

2001
Effects of protein tyrosine kinase and protein tyrosine phosphatase on apical K(+) channels in the TAL.
    American journal of physiology. Cell physiology, 2001, Volume: 281, Issue:4

    Topics: Amides; Animals; Arsenicals; Benzoquinones; CSK Tyrosine-Protein Kinase; Enzyme Inhibitors; Female; Hydroxyeicosatetraenoic Acids; Hyperkalemia; Hypokalemia; Lactams, Macrocyclic; Loop of Henle; Male; Phosphorylation; Potassium; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Quinones; Rats; Rats, Sprague-Dawley; Rifabutin; Sodium; Specific Pathogen-Free Organisms; src-Family Kinases; Sulfones

2001
The CYP450 hydroxylase pathway contributes to P2X receptor-mediated afferent arteriolar vasoconstriction.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 281, Issue:5

    Topics: Adenosine Triphosphate; Amides; Animals; Arterioles; Aryl Hydrocarbon Hydroxylases; Enzyme Inhibitors; Hydroxyeicosatetraenoic Acids; Male; Muscle, Smooth, Vascular; Potassium Chloride; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2Y1; Renal Artery; Sulfones; Uridine Triphosphate; Vasoconstriction

2001
Modulation by 20-HETE of phenylephrine-induced mesenteric artery contraction in spontaneously hypertensive and Wistar-Kyoto rats.
    Hypertension (Dallas, Tex. : 1979), 2001, Dec-01, Volume: 38, Issue:6

    Topics: Amides; Animals; Disintegrins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydroxyeicosatetraenoic Acids; Hypertension; In Vitro Techniques; Isometric Contraction; Mesenteric Arteries; Muscle, Smooth, Vascular; Phenylephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Species Specificity; Sulfones; Vasopressins; Viper Venoms

2001
Role of 20-hydroxyeicosatetraenoic acid in the renal and vasoconstrictor actions of angiotensin II.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2002, Volume: 283, Issue:1

    Topics: Amides; Angiotensin II; Animals; Arachidonic Acid; Blood Pressure; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Hydroxyeicosatetraenoic Acids; Hypertension; Kidney; Male; Mixed Function Oxygenases; Rats; Rats, Sprague-Dawley; Renal Circulation; Sulfones; Triazoles; Vasoconstriction; Vasoconstrictor Agents

2002
Arachidonic acid inhibits K channels in basolateral membrane of the thick ascending limb.
    American journal of physiology. Renal physiology, 2002, Volume: 283, Issue:3

    Topics: Amides; Animals; Arachidonic Acid; Cell Membrane; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Female; Hydroxyeicosatetraenoic Acids; Indomethacin; Loop of Henle; Male; Membrane Potentials; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Rats, Sprague-Dawley; Sulfones

2002
20-HETE pathway antagonists inhibit rat small mesenteric artery tone.
    Microvascular research, 2002, Volume: 64, Issue:2

    Topics: Amides; Animals; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; Male; Mesenteric Arteries; Pressure; Rats; Rats, Sprague-Dawley; Sulfones

2002
Transfection of CYP4A1 cDNA increases vascular reactivity in renal interlobar arteries.
    American journal of physiology. Renal physiology, 2003, Volume: 284, Issue:1

    Topics: Amides; Animals; Arachidonic Acid; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; DNA, Complementary; Gene Expression; Hydroxyeicosatetraenoic Acids; Microcirculation; Phenylephrine; Rats; Rats, Sprague-Dawley; Renal Artery; Renal Circulation; Sulfones; Transfection; Vasoconstrictor Agents

2003
Transfection of CYP4A1 cDNA decreases diameter and increases responsiveness of gracilis muscle arterioles to constrictor stimuli.
    American journal of physiology. Heart and circulatory physiology, 2004, Volume: 287, Issue:3

    Topics: Amides; Animals; Arterioles; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; DNA, Complementary; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Male; Muscle, Skeletal; Muscle, Smooth, Vascular; Phenylephrine; Rats; Rats, Sprague-Dawley; Sulfones; Transfection; Vasoconstriction; Vasoconstrictor Agents

2004
P2X receptor-stimulated calcium responses in preglomerular vascular smooth muscle cells involves 20-hydroxyeicosatetraenoic acid.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 311, Issue:3

    Topics: Adenosine Triphosphate; Amides; Animals; Calcium; Capillaries; Cell Separation; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Kidney Glomerulus; Male; Muscle, Smooth, Vascular; Purinergic P2 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2X; Renal Circulation; Spectrometry, Fluorescence; Sulfones

2004
Inhibition of cytochrome P450omega-hydroxylase: a novel endogenous cardioprotective pathway.
    Circulation research, 2004, Oct-15, Volume: 95, Issue:8

    Topics: 8,11,14-Eicosatrienoic Acid; Amides; Animals; Arachidonic Acids; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dogs; Fatty Acids, Unsaturated; Female; Hydroxyeicosatetraenoic Acids; Isoenzymes; Male; Miconazole; Microsomes; Mixed Function Oxygenases; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Sulfones

2004
Decreased levels of cytochrome P450 2E1-derived eicosanoids sensitize renal arteries to constrictor agonists in spontaneously hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 45, Issue:1

    Topics: Amides; Animals; Arachidonic Acid; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP4A; Hydroxyeicosatetraenoic Acids; Hypertension; Phenylephrine; Potassium Channel Blockers; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Artery; Sulfones; Tetraethylammonium; Vasoconstriction; Vasoconstrictor Agents; Vasopressins

2005
Effects of high-salt diet on CYP450-4A omega-hydroxylase expression and active tone in mesenteric resistance arteries.
    American journal of physiology. Heart and circulatory physiology, 2005, Volume: 288, Issue:4

    Topics: Amides; Animals; Blood Pressure; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Hydroxyeicosatetraenoic Acids; Male; Mesenteric Arteries; Mixed Function Oxygenases; Norepinephrine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium Chloride, Dietary; Sulfones; Vascular Resistance; Vasoconstrictor Agents

2005
The synthesis of 20-HETE in small porcine coronary arteries antagonizes EDHF-mediated relaxation.
    Cardiovascular research, 2005, Feb-01, Volume: 65, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Animals; Aryl Hydrocarbon Hydroxylases; Biological Factors; Coronary Vessels; Cytochrome P450 Family 4; Dose-Response Relationship, Drug; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Mixed Function Oxygenases; Protein Kinase C; Sulfones; Swine; Tetradecanoylphorbol Acetate; Vasoconstrictor Agents; Vasodilator Agents

2005
Inhibitors of cytochrome P450 4A suppress angiogenic responses.
    The American journal of pathology, 2005, Volume: 166, Issue:2

    Topics: Amides; Amidines; Animals; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Cornea; Cytochrome P-450 CYP4A; DNA, Complementary; Endothelium, Vascular; Enzyme Inhibitors; Fibroblast Growth Factor 2; Humans; Hydroxyeicosatetraenoic Acids; Male; Mitogens; Neovascularization, Pathologic; Polymerase Chain Reaction; Polymers; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sulfones; Umbilical Veins; Vascular Endothelial Growth Factor A

2005
Soluble epoxide hydrolase is a main effector of angiotensin II-induced hypertension.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 45, Issue:4

    Topics: Adamantane; Amides; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Diuresis; Epoxide Hydrolases; Hydroxyeicosatetraenoic Acids; Hypertension; In Vitro Techniques; Lauric Acids; Male; Mice; Mice, Inbred Strains; Natriuresis; Renal Circulation; Solubility; Sulfones; Vasoconstrictor Agents; Vasodilation

2005
Inhibition of 20-HETE abolishes the myogenic response during NOS antagonism in the ovine fetal pulmonary circulation.
    American journal of physiology. Lung cellular and molecular physiology, 2005, Volume: 289, Issue:2

    Topics: Amides; Animals; Drug Combinations; Ductus Arteriosus; Enzyme Inhibitors; Female; Fetus; Hydroxyeicosatetraenoic Acids; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Pregnancy; Pulmonary Artery; Pulmonary Circulation; Sheep; Sulfones; Vasoconstriction; Vasodilation

2005
Evaluation of cytochrome P450 4 family as mediator of phospholipase D activation in aortic vascular smooth muscle cells.
    Life sciences, 2005, Jul-15, Volume: 77, Issue:9

    Topics: Amides; Animals; Aorta; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; Down-Regulation; Enzyme Activation; Fenofibrate; Hydroxyeicosatetraenoic Acids; Male; Mixed Function Oxygenases; Muscle, Smooth, Vascular; Norepinephrine; Oligonucleotides, Antisense; Peroxisome Proliferators; Phospholipase D; Pyrimidines; Rabbits; Sulfones

2005
Renal 20-HETE inhibition attenuates changes in renal hemodynamics induced by L-NAME treatment in pregnant rats.
    American journal of physiology. Renal physiology, 2005, Volume: 289, Issue:5

    Topics: Age Factors; Amides; Animals; Blood Pressure; Female; Hemodynamics; Hydroxyeicosatetraenoic Acids; Kidney Cortex; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pregnancy; Pregnancy, Animal; Rats; Regional Blood Flow; Sulfones

2005
Contribution of 20-HETE to augmented myogenic constriction in coronary arteries of endothelial NO synthase knockout mice.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 46, Issue:3

    Topics: Amides; Animals; Chromatography, High Pressure Liquid; Coronary Vessels; Cytochrome P-450 CYP4A; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Male; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Nitric Oxide Synthase Type III; Pressure; Sulfones; Vasoconstriction

2005
Effects of selective inhibition of cytochrome P-450 omega-hydroxylases and ischemic preconditioning in myocardial protection.
    American journal of physiology. Heart and circulatory physiology, 2006, Volume: 290, Issue:2

    Topics: Amides; Animals; Arachidonic Acid; Cardiotonic Agents; Coronary Circulation; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dogs; Female; Hemodynamics; Hydroxyeicosatetraenoic Acids; Ischemic Preconditioning, Myocardial; Male; Mixed Function Oxygenases; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Sulfones

2006
Epoxyeicosatrienoic acids in cardioprotection: ischemic versus reperfusion injury.
    American journal of physiology. Heart and circulatory physiology, 2006, Volume: 291, Issue:2

    Topics: 8,11,14-Eicosatrienoic Acid; Amides; Animals; Arachidonic Acid; Cardiotonic Agents; Coronary Circulation; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dogs; Enzyme Inhibitors; Hemodynamics; Hydroxyeicosatetraenoic Acids; Mixed Function Oxygenases; Myocardial Ischemia; Myocardial Reperfusion Injury; Spectrometry, Mass, Electrospray Ionization; Sulfones

2006
VEGF-induced relaxation of pulmonary arteries is mediated by endothelial cytochrome P-450 hydroxylase.
    American journal of physiology. Lung cellular and molecular physiology, 2006, Volume: 291, Issue:3

    Topics: Amides; Animals; Calcium; Cattle; Cytochrome P-450 Enzyme Inhibitors; Endothelium, Vascular; Hydrolases; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Muscle Relaxation; Nitric Oxide; Pulmonary Artery; Renal Artery; Sulfones; Vascular Endothelial Growth Factor A

2006
Aging increases cytochrome P450 4A modulation of alpha1-adrenergic vasoconstriction in mesenteric arteries.
    Journal of cardiovascular pharmacology, 2008, Volume: 51, Issue:3

    Topics: Adrenergic alpha-Agonists; Aging; Amides; Animals; Cytochrome P-450 CYP4A; Endothelin-1; Hydroxyeicosatetraenoic Acids; Male; Mesenteric Arteries; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Sulfones; Vasoconstriction

2008
Cytochrome P450 omega-hydroxylase inhibition reduces cardiomyocyte apoptosis via activation of ERK1/2 signaling in rat myocardial ischemia-reperfusion.
    European journal of pharmacology, 2008, Oct-31, Volume: 596, Issue:1-3

    Topics: Amides; Amidines; Animals; Apoptosis; Caspase 3; Cytochrome P-450 CYP4A; Enzyme Activation; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardial Reperfusion Injury; Myocytes, Cardiac; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Signal Transduction; Sulfones

2008
CYP450 4A inhibition attenuates O2 induced arteriolar constriction in chronic but not acute Goldblatt hypertension.
    Microvascular research, 2009, Volume: 78, Issue:3

    Topics: Amides; Animals; Arterioles; Chronic Disease; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Disease Models, Animal; Enzyme Inhibitors; Hydroxyeicosatetraenoic Acids; Hypertension, Renovascular; Male; Muscle, Skeletal; Nephrectomy; Oxygen; Rats; Rats, Sprague-Dawley; Sulfones; Vasoconstriction

2009
Combined inhibition of 20-hydroxyeicosatetraenoic acid formation and of epoxyeicosatrienoic acids degradation attenuates hypertension and hypertension-induced end-organ damage in Ren-2 transgenic rats.
    Clinical science (London, England : 1979), 2010, Feb-23, Volume: 118, Issue:10

    Topics: 8,11,14-Eicosatrienoic Acid; Amides; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Drug Evaluation, Preclinical; Hydroxyeicosatetraenoic Acids; Hypertension; Male; Multiple Organ Failure; Norepinephrine; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Renal Circulation; Sulfones; Vasoconstrictor Agents

2010
Modulation by cytochrome P450-4A ω-hydroxylase enzymes of adrenergic vasoconstriction and response to reduced PO₂ in mesenteric resistance arteries of Dahl salt-sensitive rats.
    Microcirculation (New York, N.Y. : 1994), 2010, Volume: 17, Issue:7

    Topics: Amides; Animals; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP4A; Endothelin-1; Enzyme Inhibitors; Hydroxyeicosatetraenoic Acids; Hypoxia; In Vitro Techniques; Indomethacin; Male; Mesenteric Arteries; Microscopy, Video; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Norepinephrine; Rats; Rats, Inbred Dahl; Sodium Chloride, Dietary; Sulfones; Vascular Resistance; Vasoconstriction

2010