Compounds > dc 015
Page last updated: 2024-09-04

dc 015 and prazosin

dc 015 has been researched along with prazosin in 4 studies

Compound Research Comparison

Studies
(dc 015)		Trials
(dc 015)		Recent Studies (post-2010)
(dc 015)		Studies
(prazosin)		Trials
(prazosin)		Recent Studies (post-2010) (prazosin)
7007,914713682

Protein Interaction Comparison

ProteinTaxonomydc 015 (IC50)prazosin (IC50)
Solute carrier family 22 member 1 Homo sapiens (human)5.87
Interstitial collagenaseHomo sapiens (human)4.036
Alpha-2A adrenergic receptorHomo sapiens (human)2.638
Matrix metalloproteinase-9Homo sapiens (human)6.963
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.0008
Ribosyldihydronicotinamide dehydrogenase [quinone]Homo sapiens (human)0.0078
Alpha-2B adrenergic receptorHomo sapiens (human)0.29
Alpha-2C adrenergic receptorHomo sapiens (human)0.647
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.0008
Alpha-1D adrenergic receptorHomo sapiens (human)0.0007
Bromodomain-containing protein 2Homo sapiens (human)0.0009
Alpha-1A adrenergic receptorHomo sapiens (human)0.0006
Alpha-1B adrenergic receptorHomo sapiens (human)0.0006
5-hydroxytryptamine receptor 2BHomo sapiens (human)4.118
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.0008
5-hydroxytryptamine receptor 7Cavia porcellus (domestic guinea pig)9.9
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)1.5849
Multidrug and toxin extrusion protein 1Homo sapiens (human)1.6

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chan, CH; Chern, JW; Chien, SL; Lai, YJ; Lu, GY; Shiau, CY; Tao, PL; Yen, MH1
Huang, TF; Lee, YM; Sheu, JR; Yen, MH1
Chern, JW; Lee, YM; Peng, IH; Sheu, JR; Yen, MH1
Lee, YM; Peng, IH; Sheu, JR; Yen, MH1

Other Studies

4 other study(ies) available for dc 015 and prazosin

ArticleYear
Studies on quinazolines. 5. 2,3-dihydroimidazo[1,2-c]quinazoline derivatives: a novel class of potent and selective alpha 1-adrenoceptor antagonists and antihypertensive agents.
    Journal of medicinal chemistry, 1993, Jul-23, Volume: 36, Issue:15

    Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Binding, Competitive; Blood Pressure; Quinazolines; Rats; Rats, Inbred SHR; Structure-Activity Relationship

1993
Effect of DC-015, a novel potent and selective alpha 1-adrenoceptor antagonist, comparison with prazosin on noradrenaline-induced platelet aggregation.
    The Chinese journal of physiology, 1995, Volume: 38, Issue:2

    Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Binding, Competitive; Dose-Response Relationship, Drug; Platelet Aggregation; Platelet Aggregation Inhibitors; Prazosin; Quinazolines; Rats

1995
Pharmacological activity of DC-015, a novel potent and selective alpha 1-adrenoceptor antagonist.
    The Journal of pharmacy and pharmacology, 1996, Volume: 48, Issue:1

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Binding, Competitive; Blood Pressure; Cyclic AMP; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hypertension; Injections, Intravenous; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Phosphatidylinositols; Prazosin; Quinazolines; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Serotonin Antagonists; Vasoconstriction

1996
Effects of DC-015, a novel potent and selective alpha 1-adrenoceptor antagonist on plasma lipid and vascular reactivity in hyperlipidaemic rats.
    Clinical and experimental pharmacology & physiology, 1996, Volume: 23, Issue:3

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Aorta; Blood Pressure; Dose-Response Relationship, Drug; Hyperlipidemias; In Vitro Techniques; Lipids; Lipoproteins; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Prazosin; Quinazolines; Rats; Rats, Inbred SHR; Rats, Inbred WKY

1996