Page last updated: 2024-08-23

dazoxiben and thromboxanes

dazoxiben has been researched along with thromboxanes in 45 studies

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-199039 (86.67)18.7374
1990's4 (8.89)18.2507
2000's2 (4.44)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
McGrath, JC; Templeton, AG; Whittle, MJ1
Asai, F; Ito, T; Matsuda, K; Oshima, T; Ushiyama, S1
Aksoy, MO; Harakal, C; Smith, JB; Stewart, GJ; Zerweck, CR1
McCall, CE; Salzer, WL1
Herman, A; Kesteloot, D; Laekeman, G; Lámeire, N; Saragananda, B; Vanholder, R; Waterloos, MA1
Arnout, J; Deckmyn, H; Gresele, P; Nenci, GG; Vermylen, J1
Darius, H; Lefer, AM1
Ceuppens, JL; Deckmyn, H; Vermylen, J; Vertessen, S1
Mallarkey, G; Smith, GM1
Ernst, A; Lotz, P; Mest, HJ; Taube, C1
Coffman, TM; Klotman, PE; Yarger, WE1
Darius, H; Ferber, H; Schrör, K; Smith, EF1
FitzGerald, GA; Pedersen, AK; Reilly, IA1
Greenberg, R; Liu, EC; O'Keefe, EH; Ogletree, ML1
Dietrich, M; Nawroth, PP; Stern, DM1
Gormsen, J; Kjøller, E; Knudsen, JB; Mogensen, F; Rasmussen, V1
Parry, MJ; Saxton, CA; Tyler, HM1
Fletcher, MS; Kakkar, VV; Westwick, J1
Bertele, V; De Gaetano, G1
Harker, L; Harlan, J; Hildebrandt, J; Weaver, J; Winn, R1
Furman, BL; McKechnie, K; Parratt, JR1
Bevan, JA; Carter, AJ; Hanley, SP; Morgan, WE; Turner, DR1
Dorsch, W; Hintschich, C; Neuhauser, J; Weber, J1
Cairns, J; Gyde, OH; Kuan, P; Reuben, SR1
Randall, MJ1
Burke, SE; Lefer, AM; Smith, JB1
Patscheke, H; Stegmeier, K1
Bertelé, V; Cerletti, C; Chiabrando, C; de Gaetano, G; Falanga, A; Tomasiak, M1
Arias, M; Donoso, P; Oyarzún, MJ; Quijada, D1
Castagnoli, MN; Cerletti, C; Chiabrando, C; de Gaetano, G; Fanelli, R; Noseda, A; Rajtar, G1
Butler, RR; Cook, JA; Halushka, PV; Rambo, W; Reines, HD; Wise, WC1
FitzGerald, GA; Pedersen, AK; Watson, ML1
Deckmyn, H; Van Houtte, E; Vermylen, J; Verstraete, M1
Daskalopoulos, G; Kronborg, I; Rector, W; Reynolds, T; Zipser, RD1
Dorsch, W; Melzer, H; Ring, J1
Rücker, W; Schrör, K; Smith, EF1
Goldman, M; Hall, C; Hawker, RJ; McCollum, CN1
Davidson, JF; Hutton, I; Rankin, AC; Tweddel, AC; Walker, ID1
Bizios, R; Garcia Szabo, RR; Johnson, A; Malik, AB; Minnear, FL1
Muccitelli, RM; Osborn, RR; Weichman, BM1
Maguire, ED; Wallis, RB1
Harker, L; Harlan, J; Hildebrandt, J; Nadir, B; Winn, R1
Coker, SJ; Ledingham, IM; Parratt, JR; Zeitlin, IJ1
Fulton, CT; Stallone, JN1
Arrebola, MM; De La Cruz, JP; Escalante, R; Guerrero, A; Sánchez de La Cuesta, F; Villalobos, MA1

Reviews

2 review(s) available for dazoxiben and thromboxanes

ArticleYear
The biochemical pharmacology of thromboxane synthase inhibition in man.
    Circulation, 1985, Volume: 72, Issue:6

    Topics: Clinical Trials as Topic; Epoprostenol; Humans; Imidazoles; Platelet Aggregation; Prostaglandin Endoperoxides; Raynaud Disease; Thromboxane A2; Thromboxane-A Synthase; Thromboxanes

1985
Selective inhibition of thromboxane synthesis with dazoxiben in animals and man.
    Thrombosis research. Supplement, 1983, Volume: 4

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Fibrinolytic Agents; Humans; Imidazoles; Microsomes; Platelet Aggregation; Sheep; Swine; Thromboxane B2; Thromboxanes

1983

Trials

3 trial(s) available for dazoxiben and thromboxanes

ArticleYear
The biochemical pharmacology of thromboxane synthase inhibition in man.
    Circulation, 1985, Volume: 72, Issue:6

    Topics: Clinical Trials as Topic; Epoprostenol; Humans; Imidazoles; Platelet Aggregation; Prostaglandin Endoperoxides; Raynaud Disease; Thromboxane A2; Thromboxane-A Synthase; Thromboxanes

1985
Effects of dazoxiben on exercise performance in chronic stable angina.
    British journal of clinical pharmacology, 1983, Volume: 15 Suppl 1

    Topics: Angina Pectoris; Coronary Disease; Double-Blind Method; Humans; Imidazoles; Nitroglycerin; Oxidoreductases; Physical Exertion; Platelet Aggregation; Thrombelastography; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1983
A selective inhibitor of thromboxane biosynthesis enhances immediate and inhibits late cutaneous allergic reactions in man.
    The Journal of allergy and clinical immunology, 1983, Volume: 72, Issue:2

    Topics: Adult; Antibodies, Anti-Idiotypic; Dose-Response Relationship, Immunologic; Edema; Humans; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Imidazoles; Immunoglobulin E; Intradermal Tests; Respiratory Hypersensitivity; Thromboxanes

1983

Other Studies

41 other study(ies) available for dazoxiben and thromboxanes

ArticleYear
The role of endogenous thromboxane in contractions to U46619, oxygen, 5-HT and 5-CT in the human isolated umbilical artery.
    British journal of pharmacology, 1991, Volume: 103, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Biphenyl Compounds; Female; Heptanoic Acids; Humans; Imidazoles; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Oxygen; Pregnancy; Prostaglandin Endoperoxides, Synthetic; Prostaglandins, Synthetic; Serotonin; Thromboxane-A Synthase; Thromboxanes; Umbilical Arteries

1991
In vitro antiplatelet profiles of the new thromboxane synthetase inhibitor sodium 2-(1-imidazolylmethyl)-4,5-dihydrobenzo[b]thiophene-6-carboxylate.
    Arzneimittel-Forschung, 1991, Volume: 41, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Animals; Aspirin; Dogs; Humans; Imidazoles; In Vitro Techniques; Male; Methacrylates; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Thiophenes; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1991
Mediation of bradykinin-induced contraction in canine veins via thromboxane/prostaglandin endoperoxide receptor activation.
    British journal of pharmacology, 1990, Volume: 99, Issue:3

    Topics: Animals; Bradykinin; Bridged Bicyclo Compounds, Heterocyclic; Dogs; Endothelium, Vascular; Fatty Acids, Unsaturated; Female; Hydrazines; Imidazoles; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandin-Endoperoxide Synthases; Prostaglandins H; Pyridines; Receptors, Prostaglandin; Sulfonamides; Thromboxane-A Synthase; Thromboxanes; Veins

1990
Primed stimulation of isolated perfused rabbit lung by endotoxin and platelet activating factor induces enhanced production of thromboxane and lung injury.
    The Journal of clinical investigation, 1990, Volume: 85, Issue:4

    Topics: Animals; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Capillary Permeability; Drug Synergism; Endotoxins; Fatty Acids, Unsaturated; Hydrazines; Imidazoles; In Vitro Techniques; Indomethacin; Lipopolysaccharides; Lung; Perfusion; Platelet Activating Factor; Pulmonary Edema; Rabbits; Thromboxanes; Tumor Necrosis Factor-alpha

1990
The inhibition of thromboxane synthesis has no influence on HgCl2-induced acute renal failure in the rat.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1989, Volume: 4, Issue:7

    Topics: Acute Kidney Injury; Animals; Calcium; Glomerular Filtration Rate; Imidazoles; Indomethacin; Male; Mercuric Chloride; Natriuresis; p-Aminohippuric Acid; Rats; Rats, Inbred Strains; Thromboxane-A Synthase; Thromboxanes

1989
Characterization of N,N'-bis(3-picolyl)-4-methoxy-isophtalamide (picotamide) as a dual thromboxane synthase inhibitor/thromboxane A2 receptor antagonist in human platelets.
    Thrombosis and haemostasis, 1989, Jun-30, Volume: 61, Issue:3

    Topics: Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cyclic AMP; Fibrinolytic Agents; Humans; Imidazoles; Phthalic Acids; Platelet Aggregation Inhibitors; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Thromboxane-A Synthase; Thromboxanes

1989
Antiaggregatory effects of thromboxane receptor antagonists in vivo.
    Thrombosis research, 1985, Dec-01, Volume: 40, Issue:5

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Triphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Collagen; Fatty Acids, Unsaturated; Fibrinolytic Agents; Hydrazines; Imidazoles; Kinetics; Male; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Rabbits; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Thromboxane-A Synthase; Thromboxanes

1985
Effects of thromboxane A2 on lymphocyte proliferation.
    Cellular immunology, 1985, Volume: 90, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Antibodies, Monoclonal; Cyclooxygenase Inhibitors; Dinoprostone; Humans; Imidazoles; Indomethacin; Lymphocyte Activation; Lymphocytes; Phytohemagglutinins; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandins E; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Thromboxane A2; Thromboxane-A Synthase; Thromboxanes

1985
A comparative study of the involvement of the prostaglandin H2/thromboxane A2 pathway in intravascular platelet aggregation in guinea-pigs and rats.
    British journal of pharmacology, 1985, Volume: 84, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Collagen; Female; Guinea Pigs; Imidazoles; In Vitro Techniques; Indomethacin; Male; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Prostaglandins, Synthetic; Rats; Rats, Inbred Strains; Receptors, Prostaglandin; Receptors, Thromboxane; Species Specificity; Thromboxane A2; Thromboxane B2; Thromboxanes

1985
Dazoxiben-induced changes in the thromboxane/prostacyclin balance in the lateral cochlear wall of the guinea pig.
    Archives of oto-rhino-laryngology, 1988, Volume: 245, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cochlea; Epoprostenol; Female; Guinea Pigs; Imidazoles; Male; Thromboxane-A Synthase; Thromboxanes

1988
Functional role of thromboxane production by acutely rejecting renal allografts in rats.
    The Journal of clinical investigation, 1985, Volume: 75, Issue:4

    Topics: Animals; Cyclophosphamide; Female; Graft Rejection; Imidazoles; Inulin; Kidney; Kidney Transplantation; Male; p-Aminohippuric Acid; Prostaglandins; Rats; Thromboxanes

1985
Inhibition of thromboxane and 12-HPETE formation by dazoxiben and its two thiophenic acid-substituted derivatives.
    European journal of pharmacology, 1985, Jun-07, Volume: 112, Issue:2

    Topics: Animals; Arachidonic Acids; Blood Platelets; Cattle; Epoprostenol; Humans; Imidazoles; In Vitro Techniques; Leukotrienes; Oxidoreductases; Platelet Aggregation; Rabbits; Thiophenes; Thromboxane-A Synthase; Thromboxanes; Vasoconstriction

1985
Effects of a thromboxane synthetase inhibitor and a thromboxane antagonist on release and activity of thromboxane A2 and prostacyclin in vitro.
    Prostaglandins, 1985, Volume: 29, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Epoprostenol; Fatty Acids, Unsaturated; Guinea Pigs; Hydrazines; Imidazoles; Male; Muscle Contraction; Muscle, Smooth, Vascular; Oxidoreductases; Rats; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1985
Thromboxane production by perturbed bovine aortic endothelial cells in culture.
    Blut, 1985, Volume: 50, Issue:1

    Topics: Animals; Aorta; Aspirin; Cattle; Cells, Cultured; Clone Cells; Cycloheximide; Dactinomycin; Endothelium; Endotoxins; Imidazoles; Thromboxane B2; Thromboxanes; Time Factors

1985
Effect of specific thromboxane-synthetase inhibition on thromboxane and prostaglandin synthesis in stable angina induced by exercise test.
    Thrombosis research, 1985, Jan-15, Volume: 37, Issue:2

    Topics: Aged; Angina Pectoris; Exercise Test; Female; Humans; Imidazoles; Male; Middle Aged; Oxidoreductases; Prostaglandins; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes; Verapamil

1985
Administration to man of UK-37,248-01, a selective inhibitor of thromboxane synthetase.
    Lancet (London, England), 1981, Mar-21, Volume: 1, Issue:8221

    Topics: Administration, Oral; Adult; Dose-Response Relationship, Drug; Hemodynamics; Humans; Imidazoles; Male; Middle Aged; Oxidoreductases; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1981
Inhibition of thromboxane formation prevents endotoxin-induced renal fibrin deposition in jaundiced rats.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1983, Volume: 12

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Endotoxins; Epoprostenol; Fibrin; Imidazoles; Indomethacin; Jaundice; Kidney; Male; Rats; Rats, Inbred Strains; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1983
Potentiation by dazoxiben, a thromboxane synthetase inhibitor, of platelet aggregation inhibitory activity of a thromboxane receptor antagonist and of prostacyclin.
    European journal of pharmacology, 1982, Dec-03, Volume: 85, Issue:3-4

    Topics: Arachidonic Acids; Drug Synergism; Epoprostenol; Fatty Acids, Unsaturated; Humans; Imidazoles; In Vitro Techniques; Oxidoreductases; Platelet Aggregation; Prostaglandins; Receptors, Cell Surface; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxane A2; Thromboxane-A Synthase; Thromboxanes

1982
Selective blockade of thromboxane A2 synthesis during experimental E coli bacteremia in the goat. Effects on hemodynamics and lung water.
    Chest, 1983, Volume: 83, Issue:5 Suppl

    Topics: Animals; Body Water; Escherichia coli Infections; Goats; Hemodynamics; Imidazoles; Lung; Oxidoreductases; Sepsis; Thromboxane A2; Thromboxane-A Synthase; Thromboxanes

1983
Failure of drugs that selectively inhibit thromboxane synthesis to modify endotoxin shock in conscious rats.
    British journal of pharmacology, 1984, Volume: 82, Issue:1

    Topics: Animals; Blood Glucose; Blood Pressure; Escherichia coli; Heart Rate; Imidazoles; Lactates; Lactic Acid; Male; Platelet Count; Rats; Rats, Inbred Strains; Shock, Septic; Thromboxane B2; Thromboxanes

1984
A comparison of human pulmonary arterial and venous prostacyclin and thromboxane synthesis--effect of a thromboxane synthase inhibitor.
    Thrombosis and haemostasis, 1984, Apr-30, Volume: 51, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Endothelium; Epoprostenol; Humans; Imidazoles; Oxidoreductases; Pulmonary Artery; Pulmonary Veins; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1984
Sequential histamine inhalations cause increased bronchial histamine reactivity in guinea pigs: role of platelets, thromboxanes and prostacyclin.
    Naunyn-Schmiedeberg's archives of pharmacology, 1984, Volume: 327, Issue:2

    Topics: Animals; Aspirin; Blood Platelets; Bronchi; Bronchial Provocation Tests; Chemical Phenomena; Chemistry; Cimetidine; Epoprostenol; Guinea Pigs; Histamine; Imidazoles; Male; Platelet Aggregation; Pyridines; Receptors, Histamine H1; Receptors, Histamine H2; Thromboxane-A Synthase; Thromboxanes

1984
Role of thromboxanes and prostaglandin endoperoxides in the pathogenesis of eicosanoid induced sudden death.
    Thrombosis research, 1983, Nov-01, Volume: 32, Issue:3

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Death, Sudden; Imidazoles; Male; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandins H; Pulmonary Embolism; Rabbits; Thromboxane A2; Thromboxanes; Vasoconstriction

1983
Investigation on a selective non-prostanoic thromboxane antagonist, BM 13.177, in human platelets.
    Thrombosis research, 1984, Feb-01, Volume: 33, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Dose-Response Relationship, Drug; Epinephrine; Humans; Hydrogen Peroxide; Imidazoles; Indomethacin; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandins E; Serotonin; Sulfonamides; Thromboxane A2; Thromboxane B2; Thromboxanes

1984
Pharmacologic inhibition of thromboxane synthetase and platelet aggregation: modulatory role of cyclooxygenase products.
    Blood, 1984, Volume: 63, Issue:6

    Topics: Adult; Arachidonic Acid; Arachidonic Acids; Chromatography, Gas; Chromatography, Thin Layer; Dinoprost; Dinoprostone; Female; Humans; Imidazoles; Male; Mass Spectrometry; Oxidoreductases; Platelet Aggregation; Prostaglandin D2; Prostaglandins D; Prostaglandins E; Prostaglandins F; Radioimmunoassay; Thromboxane A2; Thromboxane-A Synthase; Thromboxanes

1984
Thromboxane mediates the increase in alveolar surfactant pool induced by free fatty acid infusion in the rabbit.
    Respiration; international review of thoracic diseases, 1984, Volume: 46, Issue:2

    Topics: Animals; Carbon Dioxide; Cyclooxygenase Inhibitors; Fatty Acids, Nonesterified; Imidazoles; Indomethacin; Lung Compliance; Male; Meclofenamic Acid; Oxygen; Pulmonary Alveoli; Pulmonary Edema; Pulmonary Surfactants; Rabbits; Thromboxane-A Synthase; Thromboxanes

1984
Comparison of radioimmunoassay and high-resolution gas chromatography mass spectrometry for the quantitative determination of serum thromboxane B2 and 6-keto-PGF1 alpha after pharmacological blockade of thromboxane synthetase.
    Prostaglandins, leukotrienes, and medicine, 1984, Volume: 16, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Arachidonic Acid; Arachidonic Acids; Gas Chromatography-Mass Spectrometry; Humans; Imidazoles; In Vitro Techniques; Oxidoreductases; Radioimmunoassay; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1984
The potential role of thromboxane and prostacyclin in endotoxic and septic shock.
    The American journal of emergency medicine, 1984, Volume: 2, Issue:1

    Topics: Animals; Arachidonic Acids; Aspirin; Cyclooxygenase Inhibitors; Epoprostenol; Fatty Acids; Gentamicins; Ibuprofen; Imidazoles; Methacrylates; Peritonitis; Rats; Rats, Inbred Strains; Shock, Septic; Thromboxane-A Synthase; Thromboxanes

1984
Inhibition of thromboxane biosynthesis in serum: limitations of the measurement of immunoreactive 6-keto-PGF1 alpha.
    Thrombosis research, 1984, Jan-01, Volume: 33, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Chemical Phenomena; Chemistry, Physical; Gas Chromatography-Mass Spectrometry; Humans; Imidazoles; Immunoassay; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1984
Manipulation of the local thromboxane and prostacyclin balance in vivo by the antithrombotic compounds dazoxiben, acetylsalicylic acid and nafazatrom.
    Biochemical pharmacology, 1983, Sep-15, Volume: 32, Issue:18

    Topics: Animals; Aspirin; Dinoprost; Drug Interactions; Fibrinolytic Agents; Functional Laterality; Imidazoles; Kinetics; Male; Prostaglandins F; Pyrazoles; Pyrazolones; Rabbits; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1983
Therapeutic trial of thromboxane synthesis inhibition in the hepatorenal syndrome.
    Gastroenterology, 1984, Volume: 87, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Acute Kidney Injury; Adult; Creatinine; Dinoprostone; Drug Evaluation; Hepatitis, Alcoholic; Humans; Imidazoles; Middle Aged; Oxidoreductases; Prostaglandins E; Syndrome; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1984
RCS from human platelets: is it only thromboxane?
    European journal of pharmacology, 1983, Nov-11, Volume: 95, Issue:1-2

    Topics: Animals; Blood Platelets; Humans; Imidazoles; In Vitro Techniques; Indomethacin; Rabbits; Thromboxane A2; Thromboxane B2; Thromboxanes

1983
Dazoxiben examined for platelet inhibitory effect in an artificial circulation.
    British journal of clinical pharmacology, 1983, Volume: 15 Suppl 1

    Topics: Adult; Blood Platelets; Blood Vessel Prosthesis; Hemodynamics; Humans; Imidazoles; In Vitro Techniques; Male; Models, Biological; Oxidoreductases; Thromboxane-A Synthase; Thromboxanes

1983
Effects of dazoxiben on transcardiac thromboxane levels and haemodynamics in coronary heart disease.
    British journal of clinical pharmacology, 1983, Volume: 15 Suppl 1

    Topics: Adult; Aged; Angina Pectoris; Coronary Circulation; Coronary Disease; Hemodynamics; Humans; Imidazoles; Middle Aged; Myocardium; Oxidoreductases; Platelet Aggregation; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1983
Role of thromboxane in the pulmonary response to pulmonary microembolization.
    Chest, 1983, Volume: 83, Issue:5 Suppl

    Topics: Animals; Cell Adhesion; Imidazoles; Leukocyte Count; Leukocytes; Pulmonary Artery; Pulmonary Embolism; Sheep; Thromboxane A2; Thromboxane-A Synthase; Thromboxanes; Vascular Resistance

1983
Effect of inhibition of thromboxane production on the leukotriene D4-mediated bronchoconstriction in the guinea pig.
    Prostaglandins, 1983, Volume: 26, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Bronchi; Chromones; Guinea Pigs; Imidazoles; Meclofenamic Acid; SRS-A; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1983
In vivo redirection of prostaglandin endoperoxides into 6-keto PGF1 alpha formation by thromboxane synthetase inhibitors in the rat.
    Thrombosis research, 1983, Oct-01, Volume: 32, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Platelets; Collagen; Imidazoles; Indoles; Indomethacin; Male; Oxidoreductases; Pyridines; Radioimmunoassay; Rats; Rats, Inbred Strains; Thrombocytopenia; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1983
Thromboxane A2 mediates lung vasoconstriction but not permeability after endotoxin.
    The Journal of clinical investigation, 1983, Volume: 72, Issue:3

    Topics: Animals; Blood Pressure; Blood Proteins; Capillary Permeability; Endotoxins; Goats; Imidazoles; Leukopenia; Lung; Lymph; Pulmonary Wedge Pressure; Thromboxane A2; Thromboxanes; Vascular Resistance; Vasoconstriction

1983
Evidence that thromboxane contributes to ventricular fibrillation induced by reperfusion of the ischaemic myocardium.
    Journal of molecular and cellular cardiology, 1982, Volume: 14, Issue:8

    Topics: Animals; Coronary Vasospasm; Dogs; Female; Imidazoles; Male; Thromboxane-A Synthase; Thromboxanes; Ventricular Fibrillation

1982
Sexual dimorphism in prostanoid-potentiated vascular contraction: roles of endothelium and ovarian steroids.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 283, Issue:5

    Topics: Animals; Aorta; Bridged Bicyclo Compounds, Heterocyclic; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Estrogens; Fatty Acids, Unsaturated; Female; Hydrazines; Imidazoles; Indomethacin; Male; Ovariectomy; Phenylephrine; Progesterone; Prostaglandins; Rats; Rats, Sprague-Dawley; Sex Characteristics; Thromboxanes; Vasoconstriction; Vasoconstrictor Agents; Vasopressins

2002
Effects of the selective inhibition of platelet thromboxane synthesis on the platelet-subendothelium interaction.
    British journal of pharmacology, 2002, Volume: 137, Issue:7

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Animals; Aspirin; Blood Platelets; Chlorobenzenes; Cyclooxygenase Inhibitors; Dinoprost; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Imidazoles; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyridines; Rabbits; Receptors, Thromboxane; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

2002