Page last updated: 2024-08-23

dazoxiben and thromboxane b2

dazoxiben has been researched along with thromboxane b2 in 86 studies

Research

Studies (86)

Timeframe	Studies, this research(%)	All Research%
pre-1990	67 (77.91)	18.7374
1990's	13 (15.12)	18.2507
2000's	6 (6.98)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bradley, MB; Gurtner, GH; Jacobson, JM; Meyers, RA; Michael, JR; Sciuto, AM	1
Arreto, CD; Bureau, MF; De Clerck, F; Lefort, J; Vargaftig, BB	1
Asai, F; Ito, T; Matsuda, K; Oshima, T; Ushiyama, S	1
Asai, F; Ito, T; Kobayashi, S; Oshima, T	1
Lin, AY; Rui, YC; Sun, DX	1
Archibald, JL; Bradley, G; Ennis, C; Opalko, A; Shepperson, NB; Ward, TJ; White, JC	1
Ennis, C; Granger, SE; Middlefell, VC; Philpot, ME; Shepperson, NB	1
Long, K; Rui, YC; Sun, DX	1
Everitt, J; Ferro, TJ; Johnson, A; Malik, AB	1
Hornberger, WB; Patscheke, H	1
Arnout, J; Bounameaux, H; Deckmyn, H; Gresele, P; Perez-Requejo, JL; Vermylen, J	1
Carmo, LG; Hatmi, M; Rotilio, D; Vargaftig, BB	1
Antonicelli, F; Hatmi, M; Haye, B; Joseph, D; Rotilio, D; Vargaftig, BB	1
Enderson, B; Price, S; Rice, CL; Winn, R	1
Bonne, C; Coquelet, C; Sincholle, D	1
Ghai, R; Lindsay, LA; Olson, RW; Sakane, Y; Smith, EF	1
Cohen, DS; Kimble, EF; Ku, EC; Olson, RW; Renfroe, HB; Smith, EF	1
Ambler, J; Butler, KD; Butler, PA; Shand, RA; Wallis, RB	1
Herman, A; Laekman, G; Lámeire, N; Vanholder, R	1
Mallarkey, G; Smith, GM	1
Dembińska-Kieć, A; Gryglewski, RJ; Korbut, R; Swies, J; Zmuda, A	1
Kort, WJ; Ouwendijk, RJ; van Ooijen, B; Vincent, JE; Westbroek, DL; Wilson, JH; Zijlstra, FJ	1
Coffman, TM; Klotman, PE; Smith, SR; Volpp, BD; Yarger, WE	1
Fenton, JW; Horgan, MJ; Malik, AB	1
Houston, DS; Shepherd, JT; Vanhoutte, PM	1
Glenn, TM; Oei, HH; Robson, RD; Sakane, Y; Zoganas, HC	1
Gerdin, B; Saldeen, T; Sandler, H	1
Honey, AC; Lad, N; Tuffin, DP	1
Bergqvist, D; Björck, CG; Dougan, P; Esquivel, CO; Lannerstad, O; Nilsson, B; Saldeen, P; Saldeen, T	1
Bertelé, V; Castagnoli, MN; Cerletti, C; de Gaetano, G; Rajtar, G	1
Patscheke, H	1
Charleson, S; Letts, LG; Lord, A	1
Greenberg, R; Liu, EC; O'Keefe, EH; Ogletree, ML	1
Malik, AB; Noonan, TC	1
Dietrich, M; Nawroth, PP; Stern, DM	1
Halushka, PV; Hunt, PS; Olanoff, LS; Reines, HD	1
Gormsen, J; Kjøller, E; Knudsen, JB; Mogensen, F; Rasmussen, V	1
Parry, MJ; Saxton, CA; Tyler, HM	1
Carreras, LO; Defreyn, G; Machin, SJ; Van Schaeren, J; Vermylen, J; Verstraete, M	1
Fletcher, MS; Kakkar, VV; Westwick, J	2
Harker, L; Harlan, J; Hildebrandt, J; Winn, R	1
Ball, HA; Parratt, JR; Zeitlin, IJ	1
Dodd, NJ; Gordge, MP; Weston, MJ	1
Davies, JA; Menys, VC	2
Brash, AR; FitzGerald, GA; Oates, JA; Pedersen, AK	1
Barfort, P; Jørgensen, KA; Kemp, E; Knudsen, JB; Larsen, S; Petersen, PH; Starklint, H	1
Furman, BL; McKechnie, K; Parratt, JR	1
Bevan, JA; Carter, AJ; Hanley, SP; Morgan, WE; Turner, DR	1
Parry, MJ	1
Cairns, J; Gyde, OH; Kuan, P; Reuben, SR	1
Randall, MJ	1
Lucchesi, BR; Schumacher, WA	1
Patscheke, H; Stegmeier, K	1
Garcia, G; Luderer, JR; Neumyer, MM; Nicholas, GG; Riley, DL; Schneck, DW; Vary, JE	1
Castagnoli, MN; Cerletti, C; Chiabrando, C; de Gaetano, G; Fanelli, R; Noseda, A; Rajtar, G	1
Stimler, NP	1
Catella, F; Filabozzi, P; Patrignani, P; Patrono, C; Pugliese, F	1
FitzGerald, GA; Pedersen, AK; Watson, ML	1
Buja, LM; Bush, LR; Campbell, WB; Tilton, GD; Willerson, JT	1
Deckmyn, H; Van Houtte, E; Vermylen, J; Verstraete, M	1
Daskalopoulos, G; Kronborg, I; Rector, W; Reynolds, T; Zipser, RD	1
Rücker, W; Schrör, K; Smith, EF	1
Atkinson, L; Bergman, G; Jewitt, DE; Kakkar, VV; Kiff, PS; Westwick, J	1
Davidson, JF; Hutton, I; Rankin, AC; Tweddel, AC; Walker, ID	1
Randall, MJ; Wilding, RI	2
Muccitelli, RM; Osborn, RR; Weichman, BM	1
Dale, J; Myhre, E; Parry, J; Thaulow, E	1
Maguire, ED; Wallis, RB	1
Lefer, AM; Okamatsu, S; Smith, EF; Smith, JB	1
Bertelé, V; Cerletti, C; de Gaetano, G; Di Minno, G; Silver, MJ	1
Dutcher, J; Isaacs, R; Mrowiec, Z; Oleksowicz, L; Puszkin, E; Zuckerman, D	1
Cho, HL; Cockerham, SL; Dillard, RD; Obenchain, RL; Pechous, PA; Silbaugh, SA; Snyder, DW; Spaethe, SM; Stengel, PW	1
Yuan, W	1
Chang, SW; Ohara, N; Voelkel, NF	1
Chang, SW; Ohara, N	1
De La Cruz, JP; García Campos, J; Moreno, A; Ruiz-Ruiz, MI; Sánchez de la Cuesta, F	1
De La Cruz, JP; Moreno, A; Ruiz-Ruiz, MI; Sánchez De La Cuesta, F	1
Bedouch, P; Bessard, G; Chavanon, O; Cracowski, JL; Devillier, P; Stanke-Labesque, F	1
Berens, ME; Djawaheri, J; Giese, A; Hagel, C; Kim, EL; Westphal, M; Zapf, S	1
Gresele, P; Mezzasoma, AM; Venditti, G; Vezza, R	1
Arrebola, MM; De La Cruz, JP; Escalante, R; Guerrero, A; Sánchez de La Cuesta, F; Villalobos, MA	2
Audoly, LP; Carty, TJ; Eskra, JD; Perez, JR; Trebino, CE; Wachtmann, TS	1

Reviews

1 review(s) available for dazoxiben and thromboxane b2

Article	Year
Selective inhibition of thromboxane synthesis with dazoxiben in animals and man. Thrombosis research. Supplement, 1983, Volume: 4 Topics: Animals; Arachidonic Acid; Arachidonic Acids; Fibrinolytic Agents; Humans; Imidazoles; Microsomes; Platelet Aggregation; Sheep; Swine; Thromboxane B2; Thromboxanes	1983

Trials

7 trial(s) available for dazoxiben and thromboxane b2

Article	Year
Thromboxane A2 and prostacyclin do not modulate the systemic hemodynamic response to cold in humans. The Journal of laboratory and clinical medicine, 1985, Volume: 106, Issue:5 Topics: 6-Ketoprostaglandin F1 alpha; Adult; beta-Thromboglobulin; Blood Pressure; Cold Temperature; Double-Blind Method; Epoprostenol; Fingers; Humans; Imidazoles; Indomethacin; Male; Platelet Aggregation; Regional Blood Flow; Sulfonamides; Thromboxane A2; Thromboxane B2; Vascular Resistance; Vasoconstriction	1985
Dazoxiben in human sepsis and adult respiratory distress syndrome. Clinical pharmacology and therapeutics, 1985, Volume: 37, Issue:4 Topics: Adult; Aged; Blood Pressure; Cardiac Output; Drug Evaluation; Female; Humans; Imidazoles; Infusions, Parenteral; Male; Middle Aged; Prospective Studies; Pulmonary Wedge Pressure; Radioimmunoassay; Random Allocation; Respiratory Distress Syndrome; Shock, Septic; Thromboxane B2; Vascular Resistance	1985
Thromboxane synthetase inhibition as antithrombotic strategy. Lancet (London, England), 1981, May-16, Volume: 1, Issue:8229 Topics: 6-Ketoprostaglandin F1 alpha; Adult; Blood Platelets; Clinical Trials as Topic; Double-Blind Method; Fibrinolytic Agents; Humans; Imidazoles; Male; Oxidoreductases; Platelet Aggregation; Prostaglandins E; Prostaglandins F; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase	1981
Use of a thromboxane synthetase inhibitor, dazoxiben, during haemodialysis. British journal of clinical pharmacology, 1983, Volume: 15 Suppl 1 Topics: 6-Ketoprostaglandin F1 alpha; Blood Coagulation; Clinical Trials as Topic; Double-Blind Method; Humans; Imidazoles; Oxidoreductases; Platelet Count; Renal Dialysis; Thromboxane B2; Thromboxane-A Synthase	1983
Endogenous prostacyclin biosynthesis and platelet function during selective inhibition of thromboxane synthase in man. The Journal of clinical investigation, 1983, Volume: 72, Issue:4 Topics: Adult; Bleeding Time; Depression, Chemical; Dose-Response Relationship, Drug; Epoprostenol; Humans; Imidazoles; Male; Oxidoreductases; Platelet Aggregation; Prostaglandins F, Synthetic; Thromboxane B2; Thromboxane-A Synthase	1983
Effects of dazoxiben on exercise performance in chronic stable angina. British journal of clinical pharmacology, 1983, Volume: 15 Suppl 1 Topics: Angina Pectoris; Coronary Disease; Double-Blind Method; Humans; Imidazoles; Nitroglycerin; Oxidoreductases; Physical Exertion; Platelet Aggregation; Thrombelastography; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes	1983
The effect of a thromboxane synthetase inhibitor, dazoxiben, and acetylsalicylic acid on platelet function and prostaglandin metabolism. Thrombosis and haemostasis, 1983, Oct-31, Volume: 50, Issue:3 Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Aspirin; Blood Platelets; Humans; Imidazoles; Male; Middle Aged; Oxidoreductases; Platelet Adhesiveness; Platelet Aggregation; Prostaglandins; Thromboxane B2; Thromboxane-A Synthase	1983

Other Studies

78 other study(ies) available for dazoxiben and thromboxane b2

Article	Year
Hyperbaric oxygen toxicity: role of thromboxane. Journal of applied physiology (Bethesda, Md. : 1985), 1992, Volume: 72, Issue:2 Topics: Animals; Bronchoalveolar Lavage Fluid; Butylated Hydroxyanisole; Hyperbaric Oxygenation; Hypertension, Pulmonary; Imidazoles; In Vitro Techniques; Indomethacin; Lung; Lung Injury; Male; Pulmonary Edema; Rabbits; Superoxide Dismutase; Thromboxane B2; Thromboxane-A Synthase	1992
Thromboxane A2 accounts for bronchoconstriction but not for platelet sequestration and microvascular albumin exchanges induced by fMLP in the guinea pig lung. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:2 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Blood Platelets; Bronchoconstriction; Guinea Pigs; Imidazoles; Lung; N-Formylmethionine Leucyl-Phenylalanine; Pentanoic Acids; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Pyridines; Radioimmunoassay; Serum Albumin; Suprofen; Thrombocytopenia; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Tretoquinol	1992
In vitro antiplatelet profiles of the new thromboxane synthetase inhibitor sodium 2-(1-imidazolylmethyl)-4,5-dihydrobenzo[b]thiophene-6-carboxylate. Arzneimittel-Forschung, 1991, Volume: 41, Issue:5 Topics: 6-Ketoprostaglandin F1 alpha; Adult; Animals; Aspirin; Dogs; Humans; Imidazoles; In Vitro Techniques; Male; Methacrylates; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Thiophenes; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes	1991
Role of activated platelets in endotoxin-induced DIC in rats. Thrombosis research, 1990, Aug-15, Volume: 59, Issue:4 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Coagulation; Disseminated Intravascular Coagulation; Endotoxins; Epoprostenol; Fibrin; Humans; Imidazoles; Kidney Glomerulus; Male; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Count; Prostaglandins, Synthetic; Rats; Rats, Inbred Strains; Sulfonamides; Thromboxane B2; Thromboxane-A Synthase; Ticlopidine	1990
[Effect of dazoxiben on the metabolism of arachidonic acid in isolated porcine basilar arteries]. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1990, Volume: 11, Issue:3 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Basilar Artery; Biological Assay; Imidazoles; In Vitro Techniques; Indomethacin; Leukotrienes; Radioimmunoassay; Swine; Thromboxane B2; Thromboxane-A Synthase	1990
Design of an antithrombotic-antihypertensive agent (Wy 27569). Synthesis and evaluation of a series of 2-heteroaryl-substituted dihydropyridines. Journal of medicinal chemistry, 1990, Volume: 33, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Antihypertensive Agents; Chemical Phenomena; Chemistry; Dihydropyridines; Drug Design; Fibrinolytic Agents; Humans; Hypertension; Imidazoles; Nitrendipine; Rats; Rats, Inbred SHR; Structure-Activity Relationship; Thromboxane B2; Thromboxane-A Synthase	1990
Pharmacologic effects of Wy 27569: a combined calcium channel blocker and thromboxane synthetase inhibitor. Journal of cardiovascular pharmacology, 1989, Volume: 13, Issue:4 Topics: Animals; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Dose-Response Relationship, Drug; Female; Humans; Imidazoles; In Vitro Techniques; Male; Nitrendipine; Prostaglandins F; Rats; Rats, Inbred SHR; Thromboxane B2; Thromboxane-A Synthase	1989
[Effect of dazoxiben on cerebrovascular resistance in rabbits]. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1989, Volume: 10, Issue:4 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cerebrovascular Circulation; Imidazoles; Male; Rabbits; Thromboxane B2; Thromboxane-A Synthase; Vascular Resistance	1989
IL-2 induces pulmonary edema and vasoconstriction independent of circulating lymphocytes. Journal of immunology (Baltimore, Md. : 1950), 1989, Mar-15, Volume: 142, Issue:6 Topics: Animals; Capillary Permeability; Endothelium, Vascular; Female; Guinea Pigs; Imidazoles; In Vitro Techniques; Interleukin-2; Killer Cells, Natural; Lymphocyte Activation; Male; Organ Size; Papaverine; Prostaglandins F; Pulmonary Edema; Pulmonary Wedge Pressure; Serum Albumin, Radio-Iodinated; Thromboxane B2; Vasoconstriction	1989
Prostaglandin H2 in human platelet activation: coactivator and substitute for thromboxane A2. Progress in clinical and biological research, 1989, Volume: 301 Topics: Blood Platelets; Humans; Imidazoles; In Vitro Techniques; Methylmercury Compounds; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Thrombin; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase	1989
Platelet desensitization induced by arachidonic acid is not due to cyclo-oxygenase inactivation and involves the endoperoxide receptor. British journal of pharmacology, 1985, Volume: 85, Issue:4 Topics: Adenosine Triphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cyclooxygenase Inhibitors; Humans; Imidazoles; Indoles; Microscopy, Electron; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Receptors, Cell Surface; Receptors, Prostaglandin; Receptors, Thromboxane; Salicylates; Thrombin; Thromboxane B2	1985
Modulation by cyclic AMP of arachidonic acid-induced platelet desensitization. European journal of pharmacology, 1986, Dec-16, Volume: 132, Issue:2-3 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenylyl Cyclases; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Bucladesine; Cyclic AMP; Humans; Imidazoles; In Vitro Techniques; Prostaglandin Endoperoxides, Synthetic; Thromboxane B2	1986
Indomethacin, but not dazoxiben, reduced lung fluid filtration after E. coli infusion. Journal of applied physiology (Bethesda, Md. : 1985), 1988, Volume: 64, Issue:6 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Body Water; Cardiac Output; Escherichia coli Infections; Imidazoles; Indomethacin; Lung; Lymph; Pulmonary Circulation; Reference Values; Thromboxane B2; Thromboxane-A Synthase	1988
Inhibition of platelet thromboxane synthetase by 1-(3-benzyloxy-1[E]octenyl)imidazole. Arzneimittel-Forschung, 1986, Volume: 36, Issue:1 Topics: Adult; Animals; Arachidonic Acid; Arachidonic Acids; Bleeding Time; Blood Platelets; Dinoprostone; Humans; Imidazoles; In Vitro Techniques; Male; Middle Aged; Prostaglandins E; Rabbits; Rats; Rats, Inbred Strains; Thrombosis; Thromboxane B2; Thromboxane-A Synthase	1986
Dazoxiben, UK 38,485 and aspirin: duration of effect for preventing thrombotic sudden death in rabbits. Thrombosis research, 1986, Jul-15, Volume: 43, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Imidazoles; Male; Rabbits; Thrombocytopenia; Thrombosis; Thromboxane B2; Time Factors	1986
CGS 15435A, a thromboxane synthetase inhibitor with an extended duration of action: a comparison with dazoxiben. European journal of pharmacology, 1987, Jan-20, Volume: 133, Issue:3 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme System; Death, Sudden; Dinoprostone; Dogs; Epoprostenol; Imidazoles; In Vitro Techniques; Indoles; Intramolecular Oxidoreductases; Lipoxygenase Inhibitors; Platelet Count; Prostaglandins E; Rabbits; Thromboxane B2; Thromboxane-A Synthase	1987
Prolongation of platelet survival in hypercholesterolaemic rabbits by CGS 12970 (3-methyl-2-(3-pyridyl)-1 indoleoctanoic acid) and dazoxiben. Thrombosis research, 1987, Mar-15, Volume: 45, Issue:6 Topics: Animals; Aspirin; Blood Platelets; Cell Survival; Cholesterol, Dietary; Cyclooxygenase Inhibitors; Hypercholesterolemia; Imidazoles; Pyridines; Rabbits; Sulfinpyrazone; Thromboxane B2; Thromboxane-A Synthase	1987
Influence of vasoactive substances on early toxic acute renal failure in the dog. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1987, Volume: 2, Issue:5 Topics: Acute Kidney Injury; Animals; Captopril; Dogs; Glomerular Filtration Rate; Imidazoles; Mercuric Chloride; Prostaglandins; Renal Circulation; Renin-Angiotensin System; Thromboxane B2; Time Factors; Verapamil	1987
A comparative study of the involvement of the prostaglandin H2/thromboxane A2 pathway in intravascular platelet aggregation in guinea-pigs and rats. British journal of pharmacology, 1985, Volume: 84, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Collagen; Female; Guinea Pigs; Imidazoles; In Vitro Techniques; Indomethacin; Male; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Prostaglandins, Synthetic; Rats; Rats, Inbred Strains; Receptors, Prostaglandin; Receptors, Thromboxane; Species Specificity; Thromboxane A2; Thromboxane B2; Thromboxanes	1985
On the mechanism of thrombolytic action of thromboxane synthetase inhibitors. Thrombosis and haemostasis, 1987, Oct-28, Volume: 58, Issue:3 Topics: Animals; Aorta; Blood Platelets; Cats; Epoprostenol; Female; Fibrinolytic Agents; Imidazoles; In Vitro Techniques; Male; Thromboxane B2; Thromboxane-A Synthase	1987
Raised plasma thromboxane B2 levels in experimental acute necrotizing pancreatitis in rats. The effects of flunarizine, dazoxiben, and indomethacin. Scandinavian journal of gastroenterology, 1988, Volume: 23, Issue:2 Topics: Acute Disease; Animals; Flunarizine; Imidazoles; Indomethacin; Male; Necrosis; Pancreatitis; Rats; Rats, Inbred Strains; Thromboxane A2; Thromboxane B2	1988
Thromboxane synthetase inhibition improves function of hydronephrotic rat kidneys. The American journal of physiology, 1986, Volume: 250, Issue:2 Pt 2 Topics: Animals; Dinoprostone; Dose-Response Relationship, Drug; Hydronephrosis; Imidazoles; Methacrylates; Prostaglandins E; Rats; Rats, Inbred Strains; Thromboxane B2; Thromboxane-A Synthase; Ureteral Obstruction	1986
Alpha-thrombin-induced pulmonary vasoconstriction. Journal of applied physiology (Bethesda, Md. : 1985), 1987, Volume: 63, Issue:5 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Female; Guinea Pigs; Hirudins; Imidazoles; Indomethacin; Lung; Male; Organ Size; Pulmonary Artery; Pulmonary Wedge Pressure; Thrombin; Thromboxane B2; Thromboxane-A Synthase; Vasoconstriction	1987
Aggregating human platelets cause direct contraction and endothelium-dependent relaxation of isolated canine coronary arteries. Role of serotonin, thromboxane A2, and adenine nucleotides. The Journal of clinical investigation, 1986, Volume: 78, Issue:2 Topics: Adenine Nucleotides; Animals; Coronary Vessels; Dogs; Endothelium; Female; Humans; Imidazoles; In Vitro Techniques; Male; Methiothepin; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Platelet Aggregation; Serotonin; Thromboxane A2; Thromboxane B2	1986
Inhibition of thromboxane biosynthesis in splanchnic ischemia shock. Circulatory shock, 1986, Volume: 18, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Cardiac Output; Dogs; Female; Glucuronidase; Heart Rate; Imidazoles; Indomethacin; Ischemia; Kinetics; Male; Shock; Splanchnic Circulation; Thromboxane B2; Thromboxane-A Synthase; Vascular Resistance	1986
Studies on the role of thromboxane in thrombin-induced pulmonary insufficiency in the rat. Thrombosis research, 1986, Apr-15, Volume: 42, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Cattle; Fibrinogen; Fibrinolysis; Imidazoles; Indomethacin; Lung; Lung Diseases; Male; Organ Size; Platelet Count; Rats; Rats, Inbred Strains; Serum Albumin; Thrombin; Thromboxane B2; Thromboxane-A Synthase	1986
Effect of indomethacin and dazoxiben on intravascular platelet aggregation in the anaesthetized rabbit. Thrombosis and haemostasis, 1986, Aug-20, Volume: 56, Issue:1 Topics: Adenosine Diphosphate; Animals; Collagen; Dose-Response Relationship, Drug; Imidazoles; Indomethacin; Male; Platelet Activating Factor; Platelet Aggregation; Rabbits; Thrombin; Thromboxane B2	1986
The effect of inhibition of thromboxane synthesis in experimental thrombosis and hemostasis. Thrombosis research, 1985, Feb-01, Volume: 37, Issue:3 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Platelets; Carotid Arteries; Female; Hemostasis; Humans; Imidazoles; Jugular Veins; Male; Oxidoreductases; Rabbits; Sheep; Thrombosis; Thromboxane B2; Thromboxane-A Synthase; Umbilical Veins	1985
Prostaglandins and human platelet aggregation. Implications for the anti-aggregating activity of thromboxane-synthase inhibitors. Biochemical pharmacology, 1985, Feb-01, Volume: 34, Issue:3 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Dinoprost; Dinoprostone; Drug Synergism; Humans; Imidazoles; Oxidoreductases; Platelet Aggregation; Prostaglandin D2; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandins; Prostaglandins D; Prostaglandins E; Prostaglandins F; Prostanoic Acids; Thromboxane B2; Thromboxane-A Synthase	1985
Thromboxane synthase inhibition potentiates washed platelet activation by endogenous and exogenous arachidonic acid. Biochemical pharmacology, 1985, Apr-15, Volume: 34, Issue:8 Topics: Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Drug Interactions; Humans; Hydrogen Peroxide; Imidazoles; In Vitro Techniques; Indomethacin; Methylmercury Compounds; Oxidoreductases; Platelet Aggregation; Serotonin; Serum Albumin; Sulfonamides; Thromboxane B2; Thromboxane-A Synthase	1985
Leukotriene F4 and the release of arachidonic acid metabolites from perfused guinea pig lungs in vitro. Prostaglandins, 1985, Volume: 29, Issue:4 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Biological Assay; Dinoprostone; Female; Guinea Pigs; Imidazoles; In Vitro Techniques; Indomethacin; Lung; Male; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; SRS-A; Thromboxane B2	1985
Effects of a thromboxane synthetase inhibitor and a thromboxane antagonist on release and activity of thromboxane A2 and prostacyclin in vitro. Prostaglandins, 1985, Volume: 29, Issue:5 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Epoprostenol; Fatty Acids, Unsaturated; Guinea Pigs; Hydrazines; Imidazoles; Male; Muscle Contraction; Muscle, Smooth, Vascular; Oxidoreductases; Rats; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes	1985
Pulmonary vascular response to leukotriene D4 in unanesthetized sheep: role of thromboxane. Journal of applied physiology (Bethesda, Md. : 1985), 1986, Volume: 60, Issue:3 Topics: Animals; Hemodynamics; Imidazoles; Lung; Lymph; Pulmonary Circulation; Sheep; SRS-A; Thromboxane B2; Wakefulness	1986
Thromboxane production by perturbed bovine aortic endothelial cells in culture. Blut, 1985, Volume: 50, Issue:1 Topics: Animals; Aorta; Aspirin; Cattle; Cells, Cultured; Clone Cells; Cycloheximide; Dactinomycin; Endothelium; Endotoxins; Imidazoles; Thromboxane B2; Thromboxanes; Time Factors	1985
Effect of specific thromboxane-synthetase inhibition on thromboxane and prostaglandin synthesis in stable angina induced by exercise test. Thrombosis research, 1985, Jan-15, Volume: 37, Issue:2 Topics: Aged; Angina Pectoris; Exercise Test; Female; Humans; Imidazoles; Male; Middle Aged; Oxidoreductases; Prostaglandins; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes; Verapamil	1985
Administration to man of UK-37,248-01, a selective inhibitor of thromboxane synthetase. Lancet (London, England), 1981, Mar-21, Volume: 1, Issue:8221 Topics: Administration, Oral; Adult; Dose-Response Relationship, Drug; Hemodynamics; Humans; Imidazoles; Male; Middle Aged; Oxidoreductases; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes	1981
Inhibition of thromboxane formation prevents endotoxin-induced renal fibrin deposition in jaundiced rats. Advances in prostaglandin, thromboxane, and leukotriene research, 1983, Volume: 12 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Endotoxins; Epoprostenol; Fibrin; Imidazoles; Indomethacin; Jaundice; Kidney; Male; Rats; Rats, Inbred Strains; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes	1983
Selective inhibition of thromboxane synthesis during experimental endotoxemia in the goat: effects on pulmonary haemodynamics and lung lymph flow. British journal of clinical pharmacology, 1983, Volume: 15 Suppl 1 Topics: Animals; Endotoxins; Escherichia coli; Goats; Hemodynamics; Imidazoles; Lung; Lymphatic System; Oxidoreductases; Pulmonary Circulation; Thromboxane B2; Thromboxane-A Synthase; Time Factors	1983
Effect of dazoxiben, a specific inhibitor of thromboxane synthetase, on acute pulmonary responses to E. coli endotoxin in anaesthetized cats. British journal of clinical pharmacology, 1983, Volume: 15 Suppl 1 Topics: Anesthesia; Animals; Cats; Endotoxins; Escherichia coli; Female; Hydrogen-Ion Concentration; Imidazoles; Lung; Male; Oxidoreductases; Thromboxane B2; Thromboxane-A Synthase; Time Factors	1983
Selective inhibition of thromboxane synthetase with dazoxiben - basis of its inhibitory effect on platelet adhesion. Thrombosis and haemostasis, 1983, Apr-28, Volume: 49, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta; Epoprostenol; Imidazoles; Male; Oxidoreductases; Platelet Adhesiveness; Rabbits; Thrombin; Thromboxane B2; Thromboxane-A Synthase	1983
The survival of pig to rabbit renal xenografts during inhibition of thromboxane synthesis. Thrombosis research, 1983, Dec-15, Volume: 32, Issue:6 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Platelets; Drug Evaluation, Preclinical; Graft Survival; Imidazoles; Kidney Transplantation; Rabbits; Swine; Thromboxane B2; Thromboxane-A Synthase; Transplantation, Heterologous	1983
Failure of drugs that selectively inhibit thromboxane synthesis to modify endotoxin shock in conscious rats. British journal of pharmacology, 1984, Volume: 82, Issue:1 Topics: Animals; Blood Glucose; Blood Pressure; Escherichia coli; Heart Rate; Imidazoles; Lactates; Lactic Acid; Male; Platelet Count; Rats; Rats, Inbred Strains; Shock, Septic; Thromboxane B2; Thromboxanes	1984
A comparison of human pulmonary arterial and venous prostacyclin and thromboxane synthesis--effect of a thromboxane synthase inhibitor. Thrombosis and haemostasis, 1984, Apr-30, Volume: 51, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Endothelium; Epoprostenol; Humans; Imidazoles; Oxidoreductases; Pulmonary Artery; Pulmonary Veins; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes	1984
Effects of thromboxane synthetase inhibition on arachidonate metabolism and platelet behaviour. British journal of clinical pharmacology, 1983, Volume: 15 Suppl 1 Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Dinoprostone; Epoprostenol; Humans; Imidazoles; In Vitro Techniques; Indomethacin; Oxidoreductases; Platelet Aggregation; Prostaglandins E; Rabbits; Thromboxane B2; Thromboxane-A Synthase	1983
Effect of the thromboxane synthetase inhibitor UK-37,248 (dazoxiben) upon platelet aggregation, coronary artery thrombosis and vascular reactivity. The Journal of pharmacology and experimental therapeutics, 1983, Volume: 227, Issue:3 Topics: Animals; Arachidonic Acid; Arachidonic Acids; Coronary Circulation; Coronary Disease; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Hyperemia; Imidazoles; Male; Oxidoreductases; Platelet Aggregation; Thromboxane B2; Thromboxane-A Synthase; Time Factors; Vasodilation	1983
Investigation on a selective non-prostanoic thromboxane antagonist, BM 13.177, in human platelets. Thrombosis research, 1984, Feb-01, Volume: 33, Issue:3 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Dose-Response Relationship, Drug; Epinephrine; Humans; Hydrogen Peroxide; Imidazoles; Indomethacin; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandins E; Serotonin; Sulfonamides; Thromboxane A2; Thromboxane B2; Thromboxanes	1984
Dazoxiben, a thromboxane synthetase inhibitor, in Raynaud's phenomenon. Clinical pharmacology and therapeutics, 1984, Volume: 36, Issue:1 Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Arachidonic Acid; Arachidonic Acids; Double-Blind Method; Drug Evaluation; Female; Forearm; Humans; Imidazoles; Male; Middle Aged; Plethysmography; Radioimmunoassay; Raynaud Disease; Thromboxane B2	1984
Comparison of radioimmunoassay and high-resolution gas chromatography mass spectrometry for the quantitative determination of serum thromboxane B2 and 6-keto-PGF1 alpha after pharmacological blockade of thromboxane synthetase. Prostaglandins, leukotrienes, and medicine, 1984, Volume: 16, Issue:1 Topics: 6-Ketoprostaglandin F1 alpha; Arachidonic Acid; Arachidonic Acids; Gas Chromatography-Mass Spectrometry; Humans; Imidazoles; In Vitro Techniques; Oxidoreductases; Radioimmunoassay; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes	1984
Spasmogenic activity of C5adesArg anaphylatoxin on guinea pig lung parenchymal strips: sensitivity of the leukotriene-mediated component to cyclooxygenase inhibitors. Biochemical and biophysical research communications, 1984, Dec-28, Volume: 125, Issue:3 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Complement C5; Complement C5a, des-Arginine; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Guinea Pigs; Imidazoles; Indomethacin; Lung; Muscle Contraction; Piroxicam; Prostaglandins E; Prostaglandins F; SRS-A; Thiazines; Thromboxane B2	1984
Differential effects of dazoxiben, a selective thromboxane-synthase inhibitor, on platelet and renal prostaglandin-endoperoxide metabolism. The Journal of pharmacology and experimental therapeutics, 1984, Volume: 228, Issue:2 Topics: Adult; Animals; Blood Platelets; Dose-Response Relationship, Drug; Female; Humans; Imidazoles; Kidney; Male; Oxidoreductases; Prostaglandin Endoperoxides; Rats; Thromboxane B2; Thromboxane-A Synthase; Time Factors	1984
Thromboxane-mediated activation of platelets and enhancement of platelet uptake onto collagen-coated glass or deendothelialized rabbit aorta. Comparative effects of a thromboxane antagonist (EPO45) and a thromboxane synthetase inhibitor (dazoxiben). Laboratory investigation; a journal of technical methods and pathology, 1984, Volume: 50, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Collagen; Imidazoles; In Vitro Techniques; Indomethacin; Male; Muscle, Smooth, Vascular; Platelet Adhesiveness; Platelet Aggregation; Prostaglandins, Synthetic; Rabbits; Serotonin; Thromboxane B2	1984
Inhibition of thromboxane biosynthesis in serum: limitations of the measurement of immunoreactive 6-keto-PGF1 alpha. Thrombosis research, 1984, Jan-01, Volume: 33, Issue:1 Topics: 6-Ketoprostaglandin F1 alpha; Chemical Phenomena; Chemistry, Physical; Gas Chromatography-Mass Spectrometry; Humans; Imidazoles; Immunoassay; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes	1984
Effects of the selective thromboxane synthetase inhibitor dazoxiben on variations in cyclic blood flow in stenosed canine coronary arteries. Circulation, 1984, Volume: 69, Issue:6 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 6-Ketoprostaglandin F1 alpha; Animals; Coronary Circulation; Coronary Disease; Coronary Vessels; Dogs; Female; Hemodynamics; Imidazoles; Male; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Thromboxane B2	1984
Manipulation of the local thromboxane and prostacyclin balance in vivo by the antithrombotic compounds dazoxiben, acetylsalicylic acid and nafazatrom. Biochemical pharmacology, 1983, Sep-15, Volume: 32, Issue:18 Topics: Animals; Aspirin; Dinoprost; Drug Interactions; Fibrinolytic Agents; Functional Laterality; Imidazoles; Kinetics; Male; Prostaglandins F; Pyrazoles; Pyrazolones; Rabbits; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes	1983
Therapeutic trial of thromboxane synthesis inhibition in the hepatorenal syndrome. Gastroenterology, 1984, Volume: 87, Issue:6 Topics: 6-Ketoprostaglandin F1 alpha; Acute Kidney Injury; Adult; Creatinine; Dinoprostone; Drug Evaluation; Hepatitis, Alcoholic; Humans; Imidazoles; Middle Aged; Oxidoreductases; Prostaglandins E; Syndrome; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes	1984
RCS from human platelets: is it only thromboxane? European journal of pharmacology, 1983, Nov-11, Volume: 95, Issue:1-2 Topics: Animals; Blood Platelets; Humans; Imidazoles; In Vitro Techniques; Indomethacin; Rabbits; Thromboxane A2; Thromboxane B2; Thromboxanes	1983
Haemodynamic and metabolic effects of dazoxiben at rest and during atrial pacing. British journal of clinical pharmacology, 1983, Volume: 15 Suppl 1 Topics: Aged; Angina Pectoris; Cardiac Pacing, Artificial; Hemodynamics; Humans; Imidazoles; Male; Middle Aged; Myocardium; Oxidoreductases; Thromboxane B2; Thromboxane-A Synthase; Time Factors	1983
Effects of dazoxiben on transcardiac thromboxane levels and haemodynamics in coronary heart disease. British journal of clinical pharmacology, 1983, Volume: 15 Suppl 1 Topics: Adult; Aged; Angina Pectoris; Coronary Circulation; Coronary Disease; Hemodynamics; Humans; Imidazoles; Middle Aged; Myocardium; Oxidoreductases; Platelet Aggregation; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes	1983
Acute arterial thrombosis in rabbits: reduced platelet accumulation after treatment with dazoxiben hydrochloride (UK 37,248-01). British journal of clinical pharmacology, 1983, Volume: 15 Suppl 1 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Blood Platelets; Electric Stimulation; Imidazoles; Indium; Male; Oxidoreductases; Rabbits; Radioisotopes; Thrombosis; Thromboxane B2; Thromboxane-A Synthase	1983
Effect of inhibition of thromboxane production on the leukotriene D4-mediated bronchoconstriction in the guinea pig. Prostaglandins, 1983, Volume: 26, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Bronchi; Chromones; Guinea Pigs; Imidazoles; Meclofenamic Acid; SRS-A; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes	1983
In vivo redirection of prostaglandin endoperoxides into 6-keto PGF1 alpha formation by thromboxane synthetase inhibitors in the rat. Thrombosis research, 1983, Oct-01, Volume: 32, Issue:1 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Platelets; Collagen; Imidazoles; Indoles; Indomethacin; Male; Oxidoreductases; Pyridines; Radioimmunoassay; Rats; Rats, Inbred Strains; Thrombocytopenia; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes	1983
Endotoxin, prostaglandins and renal fibrin deposition in obstructive jaundice. The British journal of surgery, 1982, Volume: 69, Issue:10 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cholestasis; Endotoxins; Epoprostenol; Escherichia coli; Fibrin; Imidazoles; Indomethacin; Kidney; Male; Prostaglandins; Rats; Rats, Inbred Strains; Thromboxane B2	1982
Beneficial effects of a new thromboxane synthetase inhibitor in arachidonate-induced sudden death. Thrombosis research, 1981, Aug-01, Volume: 23, Issue:3 Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Death, Sudden; Electrocardiography; Heart Rate; Imidazoles; Male; Oxidoreductases; Prostaglandins F; Pulmonary Artery; Rabbits; Serotonin; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Vasoconstrictor Agents	1981
Arachidonic acid induces human platelet-fibrin retraction: the role of platelet cyclic endoperoxides. Thrombosis research, 1982, Feb-15, Volume: 25, Issue:4 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alprostadil; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Clot Retraction; Epoprostenol; Fatty Acids, Unsaturated; Fibrin; Humans; Imidazoles; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandins D; Prostaglandins E; Prostaglandins H; Prostaglandins, Synthetic; Thromboxane B2	1982
Acute arterial thrombosis in rabbits: reduced platelet accumulation after treatment with thromboxane synthetase inhibitor dazoxiben hydrochloride, (UK-37, 248-01). Thrombosis research, 1982, Dec-01, Volume: 28, Issue:5 Topics: 6-Ketoprostaglandin F1 alpha; Acute Disease; Animals; Aspirin; Carotid Artery Thrombosis; Cells, Cultured; Enzyme Inhibitors; Fibrinolytic Agents; Imidazoles; In Vitro Techniques; Oxidoreductases; Platelet Aggregation; Rabbits; Thromboxane B2; Thromboxane-A Synthase	1982
Platelet activation induced by interleukin-6: evidence for a mechanism involving arachidonic acid metabolism. Thrombosis and haemostasis, 1994, Volume: 72, Issue:2 Topics: Adenosine Diphosphate; Arachidonic Acid; beta-Thromboglobulin; Blood Platelets; Calcimycin; Cytoskeleton; Drug Synergism; Humans; Imidazoles; Indomethacin; Interleukin-6; Platelet Activation; Prostaglandin-Endoperoxide Synthases; Recombinant Proteins; Thromboxane B2	1994
Bronchopulmonary actions of 1-(1,2,3,4-tetrahydro-1-naphthylenyl)-1H-imidazole, nitric acid salt (LY150310), a substituted imidazole, in the guinea pig. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:2 Topics: Aerosols; Animals; Antineoplastic Agents; Bronchoconstriction; Bronchoconstrictor Agents; Dinoprost; Dinoprostone; Drug Interactions; Eicosanoids; Guinea Pigs; Imidazoles; In Vitro Techniques; Lipopolysaccharides; Lung; Male; Piroxicam; Tetrahydronaphthalenes; Thromboxane B2; Trachea	1993
[Changes in renal cortical thromboxane A2, prostaglandin F1 alpha and effects of dazoxiben, chuan xiong on in situ immune complex glomerulonephritis in rats]. Zhonghua yi xue za zhi, 1993, Volume: 73, Issue:9 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Antigen-Antibody Complex; Drugs, Chinese Herbal; Glomerulonephritis; Imidazoles; Kidney Cortex; Male; Rats; Rats, Sprague-Dawley; Serum Albumin, Bovine; Thromboxane B2; Thromboxane-A Synthase	1993
Tissue eicosanoids and vascular permeability in rats with chronic biliary obstruction. Hepatology (Baltimore, Md.), 1993, Volume: 18, Issue:1 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Bile Ducts; Capillary Permeability; Cholestasis; Eicosanoids; Imidazoles; Kidney; Ligation; Liver Cirrhosis, Biliary; Lung; Male; Rats; Rats, Sprague-Dawley; Serum Albumin, Radio-Iodinated; Thromboxane A2; Thromboxane B2	1993
Increased pulmonary vascular permeability in rats with biliary cirrhosis: role of thromboxane A2. The American journal of physiology, 1993, Volume: 264, Issue:3 Pt 1 Topics: Albumins; Animals; Capillary Permeability; Eicosanoids; Imidazoles; Liver; Liver Cirrhosis, Biliary; Lung; Macrophages; Male; Microscopy, Electron; Models, Biological; Rats; Rats, Sprague-Dawley; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Vasoconstriction	1993
Effect of camonagrel, a selective thromboxane synthase inhibitor, on retinal vascularization in experimental diabetes. European journal of pharmacology, 1998, May-29, Volume: 350, Issue:1 Topics: Animals; Blood Cell Count; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Enzyme Inhibitors; Fibrinolysis; Imidazoles; Indans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Retinal Neovascularization; Streptozocin; Thromboxane B2; Thromboxane-A Synthase	1998
Effect of DT-TX 30, a combined thromboxane synthase inhibitor and thromboxane receptor antagonist, on retinal vascularity in experimental diabetes mellitus. Thrombosis research, 2000, Feb-01, Volume: 97, Issue:3 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Glucose; Chlorobenzenes; Collagen; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Enzyme Inhibitors; Imidazoles; Male; Platelet Aggregation; Pyridines; Rats; Rats, Wistar; Receptors, Thromboxane; Retinal Vessels; Thromboxane B2; Thromboxane-A Synthase	2000
Angiotensin II-induced contractions in human internal mammary artery: effects of cyclooxygenase and lipoxygenase inhibition. Cardiovascular research, 2000, Volume: 47, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Angiotensin II; Benzoquinones; Biphenyl Compounds; Cyclooxygenase Inhibitors; Depression, Chemical; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavanones; Flavonoids; Heptanoic Acids; Humans; Imidazoles; In Vitro Techniques; Indomethacin; Leukotrienes; Lipoxygenase Inhibitors; Mammary Arteries; Propionates; Pyrazoles; Quinolines; Receptors, Thromboxane; Substance P; Thromboxane B2; Thromboxane-A Synthase; Vasoconstriction	2000
Thromboxane synthase regulates the migratory phenotype of human glioma cells. Neuro-oncology, 1999, Volume: 1, Issue:1 Topics: Arachidonic Acids; Aspirin; Astrocytes; Benzofurans; Brain Neoplasms; Cell Adhesion; Cell Movement; Enzyme Induction; Enzyme Inhibitors; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioma; GTP-Binding Proteins; Humans; Imidazoles; Indomethacin; Lysine; Models, Biological; Neoplasm Proteins; Neoplastic Stem Cells; Oligodendroglia; Pentanoic Acids; Phenotype; Pyridines; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Thromboxane B2; Thromboxane-A Synthase; Tumor Cells, Cultured	1999
Prostaglandin endoperoxides and thromboxane A2 activate the same receptor isoforms in human platelets. Thrombosis and haemostasis, 2002, Volume: 87, Issue:1 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aspirin; Biphenyl Compounds; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Calcium Signaling; Cells, Cultured; Enzyme Inhibitors; Fatty Acids, Unsaturated; Heptanoic Acids; Humans; Hydrazines; Imidazoles; Inositol Phosphates; Kidney; Methacrylates; Phenylacetates; Platelet Activating Factor; Platelet Activation; Prostaglandin H2; Prostaglandins H; Protein Isoforms; Receptors, Thromboxane; Recombinant Fusion Proteins; Sulfonamides; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase	2002
Effects of the selective inhibition of platelet thromboxane synthesis on the platelet-subendothelium interaction. British journal of pharmacology, 2002, Volume: 137, Issue:7 Topics: 6-Ketoprostaglandin F1 alpha; Adult; Animals; Aspirin; Blood Platelets; Chlorobenzenes; Cyclooxygenase Inhibitors; Dinoprost; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Imidazoles; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyridines; Rabbits; Receptors, Thromboxane; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes	2002
Effects of camonagrel, a selective inhibitor of platelet thromboxane synthase, on the platelet-subendothelium interaction. Pharmacology, 2003, Volume: 69, Issue:1 Topics: Adolescent; Adult; Animals; Aspirin; Blood Platelets; Dose-Response Relationship, Drug; Humans; Imidazoles; Indans; Male; Middle Aged; Platelet Aggregation; Prostaglandins; Prostaglandins E; Rabbits; Thrombosis; Thromboxane B2; Thromboxane-A Synthase; Tunica Intima	2003
Redirection of eicosanoid metabolism in mPGES-1-deficient macrophages. The Journal of biological chemistry, 2005, Apr-29, Volume: 280, Issue:17 Topics: Animals; Arachidonic Acid; Blotting, Western; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Eicosanoids; Fatty Acids, Unsaturated; Genotype; Imidazoles; Inflammation; Intramolecular Oxidoreductases; Kinetics; Lipopolysaccharides; Macrophages; Mice; Mice, Transgenic; Microsomes; Prostaglandin-E Synthases; Prostaglandins; Thioglycolates; Thromboxane B2; Time Factors	2005