Page last updated: 2024-08-23

dazoxiben and thromboxane a2

dazoxiben has been researched along with thromboxane a2 in 63 studies

Research

Studies (63)

Timeframe	Studies, this research(%)	All Research%
pre-1990	40 (63.49)	18.7374
1990's	17 (26.98)	18.2507
2000's	5 (7.94)	29.6817
2010's	1 (1.59)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Boschetti, E; Gresele, P; Migliacci, R; Nenci, GG; Vezza, R; Volpato, R	1
Ernst, A; Mest, HJ; Syka, J	1
Arreto, CD; Bureau, MF; De Clerck, F; Lefort, J; Vargaftig, BB	1
Fiddler, GI; Lumley, P	1
Anderson, HV; Buja, LM; De Clerck, F; Golino, P; NcNatt, JM; Rosolowsky, M; Willerson, JT; Yao, SK	1
Buja, LM; De Clerck, F; Golino, P; McNatt, J; Rosolowsky, M; Willerson, JT; Yao, SK	1
Arai, Y; Urata, Y	1
Xu, LN; Yu, WG	1
Hornberger, W; Patscheke, H	1
Hatakeyama, H; Hori, Y; Kurosawa, A; Yamada, K	1
Kassell, NF; Tanaka, Y; Torner, JC	1
Ferro, T; Hocking, D; Johnson, A; Phillips, P; Tsan, MF	1
Hornberger, WB; Patscheke, H	1
Arnout, J; Bounameaux, H; Deckmyn, H; Gresele, P; Perez-Requejo, JL; Vermylen, J	1
Farber, NE; Gross, GJ; Pieper, GM	1
Carrico, CJ; Harlan, J; Hildebrandt, J; Price, S; Winn, R	1
Lad, N; Lunt, DO; Tuffin, DP	1
Andries, R; Bourgain, RH; Braquet, P; Decuyper, K	1
Ceuppens, JL; Deckmyn, H; Vermylen, J; Vertessen, S	1
Cassina, G; Livio, M; Macconi, D; Morelli, C; Morzenti, G; Remuzzi, G	1
Mallarkey, G; Smith, GM	1
Kort, WJ; Ouwendijk, RJ; van Ooijen, B; Vincent, JE; Westbroek, DL; Wilson, JH; Zijlstra, FJ	1
Garcia-Szabo, R; Johnson, A; Malik, AB	1
Awara, W; Hillier, K; Jones, D	1
Badr, KF; Brenner, BM; Kelley, VE; Rennke, HG	1
Houston, DS; Shepherd, JT; Vanhoutte, PM	1
Flynn, JT; Gee, MH; Perkowski, SZ; Tahamont, MV; Wasserman, MA	1
FitzGerald, GA; Pedersen, AK; Reilly, IA	1
Davies, JA; Martin, MF; Menys, VC; Tindall, H; Tooke, JE	1
Greenberg, R; Liu, EC; O'Keefe, EH; Ogletree, ML	1
Carter, AJ; Heptinstall, S	1
Carreras, LO; Defreyn, G; Machin, SJ; Van Schaeren, J; Vermylen, J; Verstraete, M	1
Hildebrandt, J; Lai, YL; Lamm, WJ	1
Lefer, AM; Nicolaou, KC; Smith, EF; Smith, JB	1
Bertele, V; De Gaetano, G	1
Bertelé, V; Cerletti, C; de Gaetano, G; Falanga, A; Tomasiak, M	1
Harker, L; Harlan, J; Hildebrandt, J; Weaver, J; Winn, R	1
Hawkey, CJ; Jones, EW	1
Deckmijn, H; Spitz, B; Van Assche, FA; Vermylen, J	1
Fox, SC; Heptinstall, S	1
Burke, SE; Lefer, AM; Smith, JB	1
Patscheke, H; Stegmeier, K	1
Bertelé, V; Cerletti, C; Chiabrando, C; de Gaetano, G; Falanga, A; Tomasiak, M	1
Rücker, W; Schrör, K; Smith, EF	1
Bizios, R; Garcia Szabo, RR; Johnson, A; Malik, AB; Minnear, FL	1
Lefer, AM; Okamatsu, S; Smith, EF; Smith, JB	1
Harker, L; Harlan, J; Hildebrandt, J; Nadir, B; Winn, R	1
Deckmyn, H; Defreyn, G; Vermylen, J	1
Taddei, S; Vanhoutte, PM	1
Advenier, C; Hirsch, A; Martin, CA; Molimard, M; Naline, E	1
Gryglewski, RJ; Korbut, R; Krzanowski, M; Maga, P; Musiał, J; Swies, J; Szczeklik, A	1
Calixto, JB; Campos, AH	1
Le, SQ; Mombouli, JV; Vanhoutte, PM; Wasserstrum, N	1
Chang, SW; Ohara, N; Voelkel, NF	1
Chang, SW; Ohara, N	1
Carvalho, MH; Fortes, ZB; Nigro, D; Oliveira, MA; Scivoletto, R	1
David, JL; de Leval, X; Delarge, J; Dogné, JM; Masereel, B	1
Lee, JJ; Park, SJ; Vanhoutte, PM	1
Gresele, P; Mezzasoma, AM; Venditti, G; Vezza, R	1
Duret, JF; El Habach, T; Haury, L; Tiritilli, A	1
Feletou, M; Gluais, P; Lonchampt, M; Morrow, JD; Vanhoutte, PM	1
Kuo, L; Li, M; Stallone, JN	1
Chen, X; Chu, S; Fang, W; Fei, Y; He, G; Li, Y; Wang, D; Wang, S; Wu, Q; Yang, L	1

Reviews

4 review(s) available for dazoxiben and thromboxane a2

Article	Year
Preliminary clinical studies with thromboxane synthase inhibitors and thromboxane receptor blockers. A review. Circulation, 1990, Volume: 81, Issue:1 Suppl Topics: Biphenyl Compounds; Cardiovascular Diseases; Humans; Imidazoles; Pyridines; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxane A2; Thromboxane-A Synthase	1990
[Highlights of thromboxane synthetase inhibitor research]. Sheng li ke xue jin zhan [Progress in physiology], 1990, Volume: 21, Issue:3 Topics: Animals; Epoprostenol; Humans; Imidazoles; Methacrylates; Platelet Aggregation; Thromboxane A2; Thromboxane-A Synthase	1990
The biochemical pharmacology of thromboxane synthase inhibition in man. Circulation, 1985, Volume: 72, Issue:6 Topics: Clinical Trials as Topic; Epoprostenol; Humans; Imidazoles; Platelet Aggregation; Prostaglandin Endoperoxides; Raynaud Disease; Thromboxane A2; Thromboxane-A Synthase; Thromboxanes	1985
New trends in thromboxane and prostacyclin modulators. Current medicinal chemistry, 2000, Volume: 7, Issue:6 Topics: Enzyme Inhibitors; Epoprostenol; Fibrinolytic Agents; Humans; Imidazoles; Receptors, Thromboxane; Sulfonamides; Thromboxane A2; Thromboxane-A Synthase	2000

Trials

7 trial(s) available for dazoxiben and thromboxane a2

Article	Year
Thromboxane does not play a significant role in acute, cold-induced vasoconstriction in Raynaud's phenomenon. Studies with combined thromboxane synthase inhibition and thromboxane receptor antagonism. Thrombosis research, 1992, May-01, Volume: 66, Issue:2-3 Topics: Acute Disease; Adolescent; Adult; Cold Temperature; Double-Blind Method; Female; Fingers; Humans; Imidazoles; Male; Middle Aged; Prospective Studies; Raynaud Disease; Receptors, Thromboxane; Sulfonamides; Thromboxane A2; Thromboxane-A Synthase; Vasoconstriction	1992
[Aspects of new drug development]. Nihon rinsho. Japanese journal of clinical medicine, 1990, Volume: 48, Issue:6 Topics: Chromones; Clinical Trials as Topic; Drug Design; Humans; Imidazoles; Leukotriene Antagonists; Prostaglandins; Thromboxane A2; Thromboxane-A Synthase	1990
Thromboxane A2 and prostacyclin do not modulate the systemic hemodynamic response to cold in humans. The Journal of laboratory and clinical medicine, 1985, Volume: 106, Issue:5 Topics: 6-Ketoprostaglandin F1 alpha; Adult; beta-Thromboglobulin; Blood Pressure; Cold Temperature; Double-Blind Method; Epoprostenol; Fingers; Humans; Imidazoles; Indomethacin; Male; Platelet Aggregation; Regional Blood Flow; Sulfonamides; Thromboxane A2; Thromboxane B2; Vascular Resistance; Vasoconstriction	1985
The biochemical pharmacology of thromboxane synthase inhibition in man. Circulation, 1985, Volume: 72, Issue:6 Topics: Clinical Trials as Topic; Epoprostenol; Humans; Imidazoles; Platelet Aggregation; Prostaglandin Endoperoxides; Raynaud Disease; Thromboxane A2; Thromboxane-A Synthase; Thromboxanes	1985
Effect of dazoxiben, a thromboxane synthetase inhibitor on skin-blood flow following cold challenge in patients with Raynaud's phenomenon. European journal of clinical investigation, 1985, Volume: 15, Issue:1 Topics: 6-Ketoprostaglandin F1 alpha; Cold Temperature; Drug Evaluation; Female; Fibrinopeptide A; Fingers; Humans; Imidazoles; Male; Random Allocation; Raynaud Disease; Regional Blood Flow; Skin; Thromboxane A2; Thromboxane-A Synthase	1985
Thromboxane synthetase inhibition as antithrombotic strategy. Lancet (London, England), 1981, May-16, Volume: 1, Issue:8229 Topics: 6-Ketoprostaglandin F1 alpha; Adult; Blood Platelets; Clinical Trials as Topic; Double-Blind Method; Fibrinolytic Agents; Humans; Imidazoles; Male; Oxidoreductases; Platelet Aggregation; Prostaglandins E; Prostaglandins F; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase	1981
The mechanism of anti-thrombotic, thrombolytic and fibrinolytic actions of camonagrel--a new thromboxane synthase inhibitor. Wiener klinische Wochenschrift, 1995, Volume: 107, Issue:9 Topics: Animals; Arteriosclerosis; Blood Coagulation Tests; Cats; Dose-Response Relationship, Drug; Double-Blind Method; Endothelium, Vascular; Female; Fibrinolysis; Humans; Imidazoles; Male; Middle Aged; Platelet Aggregation; Thrombosis; Thromboxane A2; Thromboxane-A Synthase; Ultrasonography, Doppler	1995

Other Studies

53 other study(ies) available for dazoxiben and thromboxane a2

Article	Year
Electrophysiological responses of the cochlea to transient asphyxia are influenced by arachidonate metabolites. Prostaglandins, 1992, Volume: 43, Issue:4 Topics: Analysis of Variance; Animals; Arachidonic Acid; Cochlear Diseases; Epoprostenol; Female; Guinea Pigs; Imidazoles; Male; Phenylacetates; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Thromboxane A2; Thromboxane-A Synthase; Time Factors	1992
Thromboxane A2 accounts for bronchoconstriction but not for platelet sequestration and microvascular albumin exchanges induced by fMLP in the guinea pig lung. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:2 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Blood Platelets; Bronchoconstriction; Guinea Pigs; Imidazoles; Lung; N-Formylmethionine Leucyl-Phenylalanine; Pentanoic Acids; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Pyridines; Radioimmunoassay; Serum Albumin; Suprofen; Thrombocytopenia; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Tretoquinol	1992
Combined thromboxane A2 synthetase inhibition and receptor blockade are effective in preventing spontaneous and epinephrine-induced canine coronary cyclic flow variations. Journal of the American College of Cardiology, 1990, Volume: 16, Issue:3 Topics: Animals; Aspirin; Bridged Bicyclo Compounds, Heterocyclic; Coronary Circulation; Coronary Disease; Dogs; Epinephrine; Epoprostenol; Ergolines; Fatty Acids, Unsaturated; Female; Hydrazines; Imidazoles; Male; Pentanoic Acids; Pyridines; Receptors, Prostaglandin; Receptors, Thromboxane; Serotonin Antagonists; Thromboxane A2; Thromboxane-A Synthase	1990
Endogenous prostaglandin endoperoxides and prostacyclin modulate the thrombolytic activity of tissue plasminogen activator. Effects of simultaneous inhibition of thromboxane A2 synthase and blockade of thromboxane A2/prostaglandin H2 receptors in a canine The Journal of clinical investigation, 1990, Volume: 86, Issue:4 Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Coronary Thrombosis; Cricetinae; Dogs; Fatty Acids, Unsaturated; Fibrinolysis; Hydrazines; Imidazoles; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandins; Receptors, Prostaglandin; Receptors, Thromboxane; Receptors, Thromboxane A2, Prostaglandin H2; Thromboxane A2; Thromboxane-A Synthase; Tissue Plasminogen Activator	1990
Transient concentrations and agonist potency of PGH2 in platelet activation by endogenous arachidonate. Eicosanoids, 1989, Volume: 2, Issue:4 Topics: Arachidonic Acid; Arachidonic Acids; Blood Platelets; Humans; Imidazoles; In Vitro Techniques; Methylmercury Compounds; Platelet Activation; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Serotonin; Thrombin; Thromboxane A2; Thromboxane-A Synthase	1989
Effect of a novel thromboxane A2 receptor antagonist, S-145, on collagen-induced ECG changes and thrombocytopenia in rodents. Japanese journal of pharmacology, 1989, Volume: 50, Issue:2 Topics: Administration, Oral; Animals; Aspirin; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Collagen; Electrocardiography; Fatty Acids, Monounsaturated; Imidazoles; In Vitro Techniques; Injections, Intravenous; Male; Mice; Mice, Inbred Strains; Prostaglandins; Rats; Receptors, Prostaglandin; Receptors, Thromboxane; Thrombocytopenia; Thromboxane A2	1989
Effects of subarachnoid hemorrhage on platelet-derived vasoconstriction of rabbit basilar artery. Surgical neurology, 1989, Volume: 32, Issue:6 Topics: Animals; Basilar Artery; Blood Platelets; Imidazoles; Indomethacin; Isometric Contraction; Ketanserin; Male; Rabbits; Serotonin; Subarachnoid Hemorrhage; Thromboxane A2; Vasoconstriction	1989
Protein kinase inhibitor prevents pulmonary edema in response to H2O2. The American journal of physiology, 1989, Volume: 256, Issue:4 Pt 2 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Capillary Permeability; Cytoskeleton; Endothelium, Vascular; Female; Guinea Pigs; Hydrogen Peroxide; Imidazoles; Isoquinolines; Male; Piperazines; Protein Kinase C; Pulmonary Artery; Pulmonary Edema; Thromboxane A2; Thromboxane-A Synthase	1989
Prostaglandin H2 in human platelet activation: coactivator and substitute for thromboxane A2. Progress in clinical and biological research, 1989, Volume: 301 Topics: Blood Platelets; Humans; Imidazoles; In Vitro Techniques; Methylmercury Compounds; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Thrombin; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase	1989
Metabolic protection of the reperfused canine endocardium by the thromboxane synthetase inhibitor, dazoxiben. Prostaglandins, leukotrienes, and essential fatty acids, 1988, Volume: 33, Issue:1 Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Coronary Circulation; Dogs; Epoprostenol; Imidazoles; Myocardial Contraction; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Thromboxane A2; Thromboxane-A Synthase	1988
Indomethacin, dazoxiben and extravascular lung water after Escherichia coli infusion. The Journal of surgical research, 1986, Volume: 41, Issue:2 Topics: Animals; Body Water; Cyclooxygenase Inhibitors; Escherichia coli Infections; Female; Imidazoles; Indomethacin; Lung; Male; Prostaglandin-Endoperoxide Synthases; Sepsis; Thromboxane A2	1986
The effect of thromboxane A2 synthesis inhibitors on platelet aggregation in whole blood. Thrombosis research, 1987, May-15, Volume: 46, Issue:4 Topics: Adult; Animals; Arachidonic Acid; Arachidonic Acids; Blood Physiological Phenomena; Collagen; Cyclooxygenase Inhibitors; Humans; Imidazoles; Indomethacin; Male; Mice; Mice, Inbred BALB C; Platelet Aggregation; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Thromboxane A2; Thromboxane-A Synthase	1987
Exchange of cyclooxygenase dependent metabolites between vessel wall and platelets in arterial thrombosis. Thrombosis research, 1988, May-01, Volume: 50, Issue:3 Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Epoprostenol; Imidazoles; Male; Mesenteric Arteries; Platelet Aggregation; Propionates; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains; Thrombosis; Thromboxane A2; Tranylcypromine	1988
Effects of thromboxane A2 on lymphocyte proliferation. Cellular immunology, 1985, Volume: 90, Issue:2 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Antibodies, Monoclonal; Cyclooxygenase Inhibitors; Dinoprostone; Humans; Imidazoles; Indomethacin; Lymphocyte Activation; Lymphocytes; Phytohemagglutinins; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandins E; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Thromboxane A2; Thromboxane-A Synthase; Thromboxanes	1985
Acetyl glycerylphosphorylcholine aggregates human platelets through two distinct pathways, both dependent on arachidonic acid metabolism. Laboratory investigation; a journal of technical methods and pathology, 1985, Volume: 52, Issue:2 Topics: 5,8,11,14-Eicosatetraynoic Acid; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Catechols; Chromatography, Thin Layer; Cyclooxygenase Inhibitors; Humans; Imidazoles; In Vitro Techniques; Lipoxygenase Inhibitors; Masoprocol; Phospholipases; Platelet Activating Factor; Platelet Aggregation; Prostanoic Acids; Quinacrine; Radioimmunoassay; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxane A2; Thromboxane-A Synthase	1985
A comparative study of the involvement of the prostaglandin H2/thromboxane A2 pathway in intravascular platelet aggregation in guinea-pigs and rats. British journal of pharmacology, 1985, Volume: 84, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Collagen; Female; Guinea Pigs; Imidazoles; In Vitro Techniques; Indomethacin; Male; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Prostaglandins, Synthetic; Rats; Rats, Inbred Strains; Receptors, Prostaglandin; Receptors, Thromboxane; Species Specificity; Thromboxane A2; Thromboxane B2; Thromboxanes	1985
Raised plasma thromboxane B2 levels in experimental acute necrotizing pancreatitis in rats. The effects of flunarizine, dazoxiben, and indomethacin. Scandinavian journal of gastroenterology, 1988, Volume: 23, Issue:2 Topics: Acute Disease; Animals; Flunarizine; Imidazoles; Indomethacin; Male; Necrosis; Pancreatitis; Rats; Rats, Inbred Strains; Thromboxane A2; Thromboxane B2	1988
Thromboxane increases pulmonary vascular resistance and transvascular fluid and protein exchange after pulmonary microembolism. Prostaglandins, 1988, Volume: 35, Issue:5 Topics: Animals; Body Water; Hemodynamics; Imidazoles; Male; Proteins; Pulmonary Circulation; Pulmonary Embolism; Sheep; Thrombin; Thromboxane A2; Vascular Resistance	1988
Kinetics of prostaglandin E2 and thromboxane A2 synthesis and suppression of PHA-stimulated peripheral blood mononuclear leucocytes. Immunology, 1986, Volume: 59, Issue:4 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Dinoprostone; Humans; Imidazoles; Kinetics; Leukocytes; Lymphocyte Activation; Male; Phytohemagglutinins; Prostaglandin Endoperoxides, Synthetic; Prostaglandins E; Prostaglandins, Synthetic; Thromboxane A2	1986
Roles for thromboxane A2 and leukotrienes in endotoxin-induced acute renal failure. Kidney international, 1986, Volume: 30, Issue:4 Topics: Acute Kidney Injury; Animals; Chromones; Dinoprostone; Endotoxins; Epoprostenol; Escherichia coli; Glomerular Filtration Rate; Imidazoles; Kidney; Male; Prostaglandins E; Rats; Rats, Inbred Strains; SRS-A; Thromboxane A2; Vascular Resistance	1986
Aggregating human platelets cause direct contraction and endothelium-dependent relaxation of isolated canine coronary arteries. Role of serotonin, thromboxane A2, and adenine nucleotides. The Journal of clinical investigation, 1986, Volume: 78, Issue:2 Topics: Adenine Nucleotides; Animals; Coronary Vessels; Dogs; Endothelium; Female; Humans; Imidazoles; In Vitro Techniques; Male; Methiothepin; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Platelet Aggregation; Serotonin; Thromboxane A2; Thromboxane B2	1986
Thromboxane as a mediator of pulmonary dysfunction during intravascular complement activation in sheep. The American review of respiratory disease, 1986, Volume: 133, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Capillary Permeability; Complement Activation; Hypertension, Pulmonary; Hypoxia; Imidazoles; Leukocytes; Lung Diseases; Plasma; Pulmonary Circulation; Sheep; Sulfonamides; Thromboxane A2; Zymosan	1986
Effects of a thromboxane synthetase inhibitor and a thromboxane antagonist on release and activity of thromboxane A2 and prostacyclin in vitro. Prostaglandins, 1985, Volume: 29, Issue:5 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Epoprostenol; Fatty Acids, Unsaturated; Guinea Pigs; Hydrazines; Imidazoles; Male; Muscle Contraction; Muscle, Smooth, Vascular; Oxidoreductases; Rats; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes	1985
Platelet aggregation in whole blood: the role of thromboxane A2 and adenosine diphosphate. Thrombosis and haemostasis, 1985, Oct-30, Volume: 54, Issue:3 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adenosine Diphosphate; Apyrase; Arachidonic Acid; Arachidonic Acids; Aspirin; Collagen; Cyclooxygenase Inhibitors; Epinephrine; Flurbiprofen; Humans; Imidazoles; In Vitro Techniques; Lipoxygenase Inhibitors; Platelet Aggregation; Pyrazoles; Thrombin; Thromboxane A2; Thromboxane-A Synthase	1985
Factors affecting massive postmortem bronchoconstriction in guinea pig lungs. Journal of applied physiology: respiratory, environmental and exercise physiology, 1984, Volume: 57, Issue:3 Topics: Animals; Bronchi; Calcium; Capsaicin; Chromones; Constriction, Pathologic; Diethylcarbamazine; Guinea Pigs; Imidazoles; Male; Postmortem Changes; Pulmonary Circulation; SRS-A; Substance P; Thromboxane A2	1984
Thromboxane synthetase inhibitors differentially antagonize thromboxane receptors in vascular smooth muscle. Naunyn-Schmiedeberg's archives of pharmacology, 1981, Volume: 318, Issue:2 Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bicyclic Monoterpenes; Blood Platelets; Cats; Coronary Vessels; Imidazoles; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Oxidoreductases; Pulmonary Artery; Receptors, Cell Surface; Receptors, Prostaglandin; Receptors, Thromboxane; Serotonin; Thromboxane A2; Thromboxane-A Synthase	1981
Potentiation by dazoxiben, a thromboxane synthetase inhibitor, of platelet aggregation inhibitory activity of a thromboxane receptor antagonist and of prostacyclin. European journal of pharmacology, 1982, Dec-03, Volume: 85, Issue:3-4 Topics: Arachidonic Acids; Drug Synergism; Epoprostenol; Fatty Acids, Unsaturated; Humans; Imidazoles; In Vitro Techniques; Oxidoreductases; Platelet Aggregation; Prostaglandins; Receptors, Cell Surface; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxane A2; Thromboxane-A Synthase; Thromboxanes	1982
SQ 22536, an adenylate-cyclase inhibitor, prevents the antiplatelet effect of dazoxiben, a thromboxane-synthetase inhibitor. Thrombosis and haemostasis, 1984, Feb-28, Volume: 51, Issue:1 Topics: Adenine; Adenylyl Cyclase Inhibitors; Blood Platelets; Cyclic AMP; Humans; Imidazoles; Oxidoreductases; Platelet Aggregation; Prostaglandin D2; Prostaglandins D; Thromboxane A2; Thromboxane-A Synthase	1984
Selective blockade of thromboxane A2 synthesis during experimental E coli bacteremia in the goat. Effects on hemodynamics and lung water. Chest, 1983, Volume: 83, Issue:5 Suppl Topics: Animals; Body Water; Escherichia coli Infections; Goats; Hemodynamics; Imidazoles; Lung; Oxidoreductases; Sepsis; Thromboxane A2; Thromboxane-A Synthase; Thromboxanes	1983
A thromboxane synthetase inhibitor in Raynaud's phenomenon. Prostaglandins, leukotrienes, and medicine, 1983, Volume: 12, Issue:1 Topics: Adult; Body Temperature; Double-Blind Method; Epoprostenol; Female; Fingers; Humans; Imidazoles; Male; Middle Aged; Oxidoreductases; Raynaud Disease; Thromboxane A2; Thromboxane-A Synthase; Vasoconstriction	1983
Preliminary observations on treatment of pregnancy-induced hypertension with a thromboxane synthetase inhibitor. American journal of obstetrics and gynecology, 1984, Jan-15, Volume: 148, Issue:2 Topics: Adult; Epoprostenol; Female; Humans; Hypertension; Imidazoles; Oxidoreductases; Pregnancy; Pregnancy Complications, Cardiovascular; Thromboxane A2; Thromboxane-A Synthase	1984
Human blood platelet behaviour after inhibition of thromboxane synthetase. British journal of clinical pharmacology, 1983, Volume: 15 Suppl 1 Topics: Arachidonic Acid; Arachidonic Acids; Blood Platelets; Humans; Imidazoles; In Vitro Techniques; Malondialdehyde; Oxidoreductases; Serotonin; Thromboxane A2; Thromboxane-A Synthase	1983
Role of thromboxanes and prostaglandin endoperoxides in the pathogenesis of eicosanoid induced sudden death. Thrombosis research, 1983, Nov-01, Volume: 32, Issue:3 Topics: Animals; Arachidonic Acid; Arachidonic Acids; Death, Sudden; Imidazoles; Male; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandins H; Pulmonary Embolism; Rabbits; Thromboxane A2; Thromboxanes; Vasoconstriction	1983
Investigation on a selective non-prostanoic thromboxane antagonist, BM 13.177, in human platelets. Thrombosis research, 1984, Feb-01, Volume: 33, Issue:3 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Dose-Response Relationship, Drug; Epinephrine; Humans; Hydrogen Peroxide; Imidazoles; Indomethacin; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandins E; Serotonin; Sulfonamides; Thromboxane A2; Thromboxane B2; Thromboxanes	1984
Pharmacologic inhibition of thromboxane synthetase and platelet aggregation: modulatory role of cyclooxygenase products. Blood, 1984, Volume: 63, Issue:6 Topics: Adult; Arachidonic Acid; Arachidonic Acids; Chromatography, Gas; Chromatography, Thin Layer; Dinoprost; Dinoprostone; Female; Humans; Imidazoles; Male; Mass Spectrometry; Oxidoreductases; Platelet Aggregation; Prostaglandin D2; Prostaglandins D; Prostaglandins E; Prostaglandins F; Radioimmunoassay; Thromboxane A2; Thromboxane-A Synthase; Thromboxanes	1984
RCS from human platelets: is it only thromboxane? European journal of pharmacology, 1983, Nov-11, Volume: 95, Issue:1-2 Topics: Animals; Blood Platelets; Humans; Imidazoles; In Vitro Techniques; Indomethacin; Rabbits; Thromboxane A2; Thromboxane B2; Thromboxanes	1983
Role of thromboxane in the pulmonary response to pulmonary microembolization. Chest, 1983, Volume: 83, Issue:5 Suppl Topics: Animals; Cell Adhesion; Imidazoles; Leukocyte Count; Leukocytes; Pulmonary Artery; Pulmonary Embolism; Sheep; Thromboxane A2; Thromboxane-A Synthase; Thromboxanes; Vascular Resistance	1983
Beneficial effects of a new thromboxane synthetase inhibitor in arachidonate-induced sudden death. Thrombosis research, 1981, Aug-01, Volume: 23, Issue:3 Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Death, Sudden; Electrocardiography; Heart Rate; Imidazoles; Male; Oxidoreductases; Prostaglandins F; Pulmonary Artery; Rabbits; Serotonin; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Vasoconstrictor Agents	1981
Thromboxane A2 mediates lung vasoconstriction but not permeability after endotoxin. The Journal of clinical investigation, 1983, Volume: 72, Issue:3 Topics: Animals; Blood Pressure; Blood Proteins; Capillary Permeability; Endotoxins; Goats; Imidazoles; Leukopenia; Lung; Lymph; Pulmonary Wedge Pressure; Thromboxane A2; Thromboxanes; Vascular Resistance; Vasoconstriction	1983
A thromboxane synthetase inhibitor reorients endoperoxide metabolism in whole blood towards prostacyclin and prostaglandin E2. Thrombosis research, 1982, Jun-15, Volume: 26, Issue:6 Topics: Blood Platelets; Collagen; Dinoprostone; Epoprostenol; Humans; Imidazoles; In Vitro Techniques; Oxidoreductases; Prostaglandin Endoperoxides; Prostaglandins; Prostaglandins E; Thromboxane A2; Thromboxane-A Synthase	1982
Endothelium-dependent contractions to endothelin in the rat aorta are mediated by thromboxane A2. Journal of cardiovascular pharmacology, 1993, Volume: 22 Suppl 8 Topics: Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Bridged Bicyclo Compounds, Heterocyclic; Endothelins; Endothelium, Vascular; Fatty Acids, Unsaturated; Hydrazines; Imidazoles; In Vitro Techniques; Indomethacin; Isometric Contraction; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitroarginine; Radioimmunoassay; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Thromboxane A2; Thromboxane-A Synthase	1993
Role of thromboxane A2 in bradykinin-induced human isolated small bronchi contraction. European journal of pharmacology, 1995, May-04, Volume: 278, Issue:1 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Aged; Biphenyl Compounds; Bradykinin; Bronchi; Capsaicin; Dose-Response Relationship, Drug; Heptanoic Acids; Humans; Imidazoles; Indomethacin; Male; Middle Aged; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Prostaglandin Endoperoxides, Synthetic; Receptors, Thromboxane; Ruthenium Red; Thromboxane A2; Thromboxane-A Synthase; Vasoconstrictor Agents	1995
Mechanisms involved in the contractile responses of kinins in rat portal vein rings: mediation by B1 and B2 receptors. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:2 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bradykinin; Cycloheximide; Dose-Response Relationship, Drug; Imidazoles; In Vitro Techniques; Indoles; Male; Norepinephrine; Portal Vein; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Wistar; Receptors, Bradykinin; Thromboxane A2; Vasoconstriction	1994
Contractile effect of endothelin in human placental veins: role of endothelium prostaglandins and thromboxane. American journal of obstetrics and gynecology, 1993, Volume: 169, Issue:4 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Bridged Bicyclo Compounds, Heterocyclic; Endothelins; Endothelium, Vascular; Fatty Acids, Unsaturated; Female; Humans; Hydrazines; Imidazoles; In Vitro Techniques; Indomethacin; Placenta; Pregnancy; Prostaglandin Endoperoxides, Synthetic; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Thromboxane A2; Thromboxane-A Synthase; Vasoconstriction; Vasoconstrictor Agents; Veins	1993
Tissue eicosanoids and vascular permeability in rats with chronic biliary obstruction. Hepatology (Baltimore, Md.), 1993, Volume: 18, Issue:1 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Bile Ducts; Capillary Permeability; Cholestasis; Eicosanoids; Imidazoles; Kidney; Ligation; Liver Cirrhosis, Biliary; Lung; Male; Rats; Rats, Sprague-Dawley; Serum Albumin, Radio-Iodinated; Thromboxane A2; Thromboxane B2	1993
Increased pulmonary vascular permeability in rats with biliary cirrhosis: role of thromboxane A2. The American journal of physiology, 1993, Volume: 264, Issue:3 Pt 1 Topics: Albumins; Animals; Capillary Permeability; Eicosanoids; Imidazoles; Liver; Liver Cirrhosis, Biliary; Lung; Macrophages; Male; Microscopy, Electron; Models, Biological; Rats; Rats, Sprague-Dawley; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Vasoconstriction	1993
The role of thromboxane A2 in the altered microvascular reactivity in two-kidney, one-clip hypertension. Endothelium : journal of endothelial cell research, 1997, Volume: 5, Issue:3 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arterioles; Enzyme Inhibitors; Hypertension, Renovascular; Imidazoles; Male; Mesentery; Microcirculation; Nitric Oxide; Nitroprusside; Pentanoic Acids; Perfusion; Pyridines; Rats; Rats, Wistar; Receptors, Prostaglandin; Receptors, Thromboxane; Receptors, Thromboxane A2, Prostaglandin H2; Renal Circulation; Thromboxane A2; Thromboxane-A Synthase; Vascular Resistance; Vasoconstrictor Agents	1997
Endothelin-1 releases endothelium-derived endoperoxides and thromboxane A2 in porcine coronary arteries with regenerated endothelium. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1999, Volume: 20, Issue:10 Topics: Animals; Coronary Vessels; Cyclooxygenase Inhibitors; Endothelin-1; Endothelium, Vascular; Imidazoles; Indomethacin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroarginine; Pentanoic Acids; Pyridines; Swine; Thromboxane A2; Thromboxane-A Synthase	1999
Prostaglandin endoperoxides and thromboxane A2 activate the same receptor isoforms in human platelets. Thrombosis and haemostasis, 2002, Volume: 87, Issue:1 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aspirin; Biphenyl Compounds; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Calcium Signaling; Cells, Cultured; Enzyme Inhibitors; Fatty Acids, Unsaturated; Heptanoic Acids; Humans; Hydrazines; Imidazoles; Inositol Phosphates; Kidney; Methacrylates; Phenylacetates; Platelet Activating Factor; Platelet Activation; Prostaglandin H2; Prostaglandins H; Protein Isoforms; Receptors, Thromboxane; Recombinant Fusion Proteins; Sulfonamides; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase	2002
BK2 but not BK1 receptors mediating contractile response in human umbilical arteries: role of thromboxane A2. Methods and findings in experimental and clinical pharmacology, 2004, Volume: 26, Issue:4 Topics: Bradykinin; Bradykinin B1 Receptor Antagonists; Bradykinin B2 Receptor Antagonists; Dose-Response Relationship, Drug; Endothelium; Humans; Imidazoles; Indomethacin; Masoprocol; Muscle Contraction; Muscle, Smooth, Vascular; Quinacrine; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Thromboxane A2; Umbilical Arteries	2004
Acetylcholine-induced endothelium-dependent contractions in the SHR aorta: the Janus face of prostacyclin. British journal of pharmacology, 2005, Volume: 146, Issue:6 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Aorta, Thoracic; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Hypertension; Imidazoles; In Vitro Techniques; Indomethacin; Nitrobenzenes; Prostaglandins; Prostaglandins I; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Salicylates; Sulfonamides; Thromboxane A2; Vasoconstriction; Vasoconstrictor Agents	2005
Estrogen potentiates constrictor prostanoid function in female rat aorta by upregulation of cyclooxygenase-2 and thromboxane pathway expression. American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:6 Topics: Animals; Aorta, Thoracic; Cyclooxygenase 1; Cyclooxygenase 2; Drug Implants; Endothelium, Vascular; Enzyme Induction; Enzyme Inhibitors; Epoprostenol; Estradiol; Female; Imidazoles; Immunohistochemistry; Male; Membrane Proteins; Muscle, Smooth, Vascular; Ovariectomy; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Thromboxane; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Thromboxane A2; Thromboxane-A Synthase; Up-Regulation; Vasoconstriction; Vasopressins	2008
N2 extenuates experimental ischemic stroke through platelet aggregation inhibition. Thrombosis research, 2015, Volume: 136, Issue:6 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Arteriovenous Shunt, Surgical; Blood Coagulation; Brain; Brain Ischemia; Edema; Enzyme-Linked Immunosorbent Assay; Epoprostenol; Female; Imidazoles; Male; Maze Learning; Platelet Aggregation; Rats; Rats, Sprague-Dawley; Stroke; Thrombosis; Thromboxane A2; Vanillic Acid	2015