Page last updated: 2024-08-23

dazoxiben and indomethacin

dazoxiben has been researched along with indomethacin in 58 studies

Research

Studies (58)

TimeframeStudies, this research(%)All Research%
pre-199034 (58.62)18.7374
1990's15 (25.86)18.2507
2000's6 (10.34)29.6817
2010's3 (5.17)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Banner, BL; Chiu, AM; Cohen, N; Focella, A; Lopresti, RJ; O'Donnell, M; Schaer, B; Todaro, L; Weber, G; Zenchoff, GB1
Arita, H; Doteuchi, M; Hanasaki, K; Hara, S; Kakushi, H; Narisada, M; Ohtani, M; Otani, K; Uchida, K; Watanabe, F1
Allanson, NM; Buckle, PE; Lad, N; Lai, SM; Lunt, DO; Manley, PW; Porter, RA; Tuffin, DP; Wade, PJ1
Cross, PE; Dickinson, RP; Parry, MJ; Randall, MJ1
Houghton, PJ; Hoult, JR; Liao, YH1
Dannhardt, G; Frotscher, M; Hartmann, RW; Jacobs, C1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Bradley, MB; Gurtner, GH; Jacobson, JM; Meyers, RA; Michael, JR; Sciuto, AM1
Dabros, W; Gryglewski, RJ; Korbut, R; Ocetkiewicz, A1
Lin, AY; Rui, YC; Sun, DX1
McCall, CE; Salzer, WL1
Dorigo, O; Kübler, W; Neumann, FJ; Parekh, N; Steinhausen, M; Tiefenbacher, C; Tillmanns, H; Zimmermann, R1
Hornberger, W; Patscheke, H1
Herman, A; Kesteloot, D; Laekeman, G; Lámeire, N; Saragananda, B; Vanholder, R; Waterloos, MA1
Kassell, NF; Tanaka, Y; Torner, JC1
Arnout, J; Bounameaux, H; Deckmyn, H; Gresele, P; Perez-Requejo, JL; Vermylen, J1
Arnout, J; Deckmyn, H; Gresele, P; Huybrechts, E; Pieters, G; Vermylen, J1
Enderson, B; Price, S; Rice, CL; Winn, R1
Carrico, CJ; Harlan, J; Hildebrandt, J; Price, S; Winn, R1
Lad, N; Lunt, DO; Tuffin, DP1
Katusic, ZS; Shepherd, JT; Vanhoutte, PM1
Ceuppens, JL; Deckmyn, H; Vermylen, J; Vertessen, S1
Mallarkey, G; Smith, GM1
Kort, WJ; Ouwendijk, RJ; van Ooijen, B; Vincent, JE; Westbroek, DL; Wilson, JH; Zijlstra, FJ1
Fenton, JW; Horgan, MJ; Malik, AB1
Glenn, TM; Oei, HH; Robson, RD; Sakane, Y; Zoganas, HC1
Gerdin, B; Saldeen, T; Sandler, H1
Honey, AC; Lad, N; Tuffin, DP1
Hillyard, CJ; Martin, TJ; Nolan, RD; Partridge, NC1
Patscheke, H1
Charleson, S; Letts, LG; Lord, A1
De Garis, RM; Dusting, GJ; Li, DM1
Bounameaux, H; Collen, D; De Cock, F; Gresele, P; Hanss, M; Vermylen, J1
Fletcher, MS; Kakkar, VV; Westwick, J2
Parry, MJ1
Patscheke, H; Stegmeier, K1
Arias, M; Donoso, P; Oyarzún, MJ; Quijada, D1
Stimler, NP1
Davies, JA; Menys, VC1
Rücker, W; Schrör, K; Smith, EF1
Maguire, ED; Wallis, RB1
Taddei, S; Vanhoutte, PM1
Advenier, C; Hirsch, A; Martin, CA; Molimard, M; Naline, E1
de Lima, WT; Jancar, S; Kwasniewski, FH; Sirois, P1
Dutcher, J; Isaacs, R; Mrowiec, Z; Oleksowicz, L; Puszkin, E; Zuckerman, D1
de Carvalho, MH; Fortes, ZB; Nigro, D; Sannomiya, P; Scivoletto, R1
Le, SQ; Mombouli, JV; Vanhoutte, PM; Wasserstrum, N1
Gao, Y; Vanhoutte, PM1
Bedouch, P; Bessard, G; Chavanon, O; Cracowski, JL; Devillier, P; Stanke-Labesque, F1
Lee, JJ; Park, SJ; Vanhoutte, PM1
Berens, ME; Djawaheri, J; Giese, A; Hagel, C; Kim, EL; Westphal, M; Zapf, S1
Fulton, CT; Stallone, JN1
Calixto, JB; El Sayah, M1
Duret, JF; El Habach, T; Haury, L; Tiritilli, A1
Feletou, M; Gluais, P; Lonchampt, M; Morrow, JD; Vanhoutte, PM1
Campbell, WB; Nithipatikom, K; Pfister, SL1
Aschner, JL; Fike, CD; Kaplowitz, MR; Pfister, SL; Slaughter, JC; Zhang, Y1

Trials

3 trial(s) available for dazoxiben and indomethacin

ArticleYear
Thromboxane A2 and prostacyclin do not modulate the systemic hemodynamic response to cold in humans.
    The Journal of laboratory and clinical medicine, 1985, Volume: 106, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; beta-Thromboglobulin; Blood Pressure; Cold Temperature; Double-Blind Method; Epoprostenol; Fingers; Humans; Imidazoles; Indomethacin; Male; Platelet Aggregation; Regional Blood Flow; Sulfonamides; Thromboxane A2; Thromboxane B2; Vascular Resistance; Vasoconstriction

1985
Role of proaggregatory and antiaggregatory prostaglandins in hemostasis. Studies with combined thromboxane synthase inhibition and thromboxane receptor antagonism.
    The Journal of clinical investigation, 1987, Volume: 80, Issue:5

    Topics: Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Bleeding Time; Cyclooxygenase Inhibitors; Hemostasis; Humans; Imidazoles; Indomethacin; Male; Platelet Aggregation; Prostaglandins; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Thromboxane-A Synthase

1987
Aspirin, indomethacin and dazoxiben do not affect the fibrinolytic activation induced by venous occlusion.
    Thrombosis research, 1985, Oct-15, Volume: 40, Issue:2

    Topics: Aspirin; Double-Blind Method; Fibrinolysis; Humans; Imidazoles; Indomethacin; Male; Prostaglandins; Serum Globulins; Tissue Plasminogen Activator; Vascular Diseases; Veins

1985

Other Studies

55 other study(ies) available for dazoxiben and indomethacin

ArticleYear
3,4-Dihydro-2H-1-benzopyran-2-carboxylic acids and related compounds as leukotriene antagonists.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:8

    Topics: Animals; Benzopyrans; Chemical Phenomena; Chemistry; Chromans; Guinea Pigs; Leukotriene Antagonists; Male; Models, Molecular; Rats; Receptors, Immunologic; Receptors, Leukotriene; Stereoisomerism; Structure-Activity Relationship

1989
Synthesis and in vitro activity of various derivatives of a novel thromboxane receptor antagonist, (+/-)-(5Z)-7-[3-endo-[(phenylsulfonyl)amino]bicyclo[2.2.1] hept-2-exo-yl]heptenoic acid.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:9

    Topics: Animals; Aorta; Blood Platelets; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Chemical Phenomena; Chemistry; Fatty Acids, Monounsaturated; Humans; Male; Methylation; Muscle Contraction; Platelet Aggregation; Rabbits; Rats; Receptors, Prostaglandin; Receptors, Thromboxane; Stereoisomerism; Structure-Activity Relationship; Sulfur; Thrombin; Thromboxane A2

1988
Thromboxane synthase inhibitors. Synthesis and pharmacological activity of (R)-, (S)-, and (+/-)-2,2-dimethyl-6-[2-(1H-imidazol-1-yl)-1-[[(4-methoxyphenyl)- methoxy]methyl]ethoxy]hexanoic acids.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:10

    Topics: 6-Ketoprostaglandin F1 alpha; Administration, Oral; Animals; Caproates; Collagen; Enzyme Inhibitors; Guinea Pigs; Humans; Imidazoles; Kinetics; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Stereoisomerism; Thromboxane B2; Thromboxane-A Synthase

1987
Selective thromboxane synthetase inhibitors. 1. 1-[(Aryloxy)alkyl]-1H-imidazoles.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:10

    Topics: Animals; Chemical Phenomena; Chemistry; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme System; Epoprostenol; Imidazoles; Intramolecular Oxidoreductases; Male; Sheep; Steroid 11-beta-Hydroxylase; Structure-Activity Relationship; Thromboxane-A Synthase

1985
Novel and known constituents from Buddleja species and their activity against leukocyte eicosanoid generation.
    Journal of natural products, 1999, Volume: 62, Issue:9

    Topics: Animals; Cyclooxygenase Inhibitors; Eicosanoids; Glycosides; Leukocytes; Lipoxygenase Inhibitors; Medicine, Chinese Traditional; Plant Extracts; Plants, Medicinal; Rats; Spectrum Analysis

1999
1-imidazolyl(alkyl)-substituted di- and tetrahydroquinolines and analogues: syntheses and evaluation of dual inhibitors of thromboxane A(2) synthase and aromatase.
    Journal of medicinal chemistry, 2000, May-04, Volume: 43, Issue:9

    Topics: Animals; Aromatase Inhibitors; Enzyme Inhibitors; Humans; Imidazoles; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Microsomes; Quinolines; Rats; Rats, Sprague-Dawley; Spectrophotometry, Ultraviolet; Substrate Specificity; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase

2000
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Hyperbaric oxygen toxicity: role of thromboxane.
    Journal of applied physiology (Bethesda, Md. : 1985), 1992, Volume: 72, Issue:2

    Topics: Animals; Bronchoalveolar Lavage Fluid; Butylated Hydroxyanisole; Hyperbaric Oxygenation; Hypertension, Pulmonary; Imidazoles; In Vitro Techniques; Indomethacin; Lung; Lung Injury; Male; Pulmonary Edema; Rabbits; Superoxide Dismutase; Thromboxane B2; Thromboxane-A Synthase

1992
A biological method for studying the interaction between platelets and vascular endothelium.
    Thrombosis research, 1990, Feb-01, Volume: 57, Issue:3

    Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Aspirin; Blood Platelets; Endothelium, Vascular; Epoprostenol; Imidazoles; Indomethacin; Leukotrienes; Lipid Peroxides; Platelet Adhesiveness; Rabbits; Superoxide Dismutase; Thrombosis; Xanthine; Xanthine Oxidase; Xanthines

1990
[Effect of dazoxiben on the metabolism of arachidonic acid in isolated porcine basilar arteries].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1990, Volume: 11, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Basilar Artery; Biological Assay; Imidazoles; In Vitro Techniques; Indomethacin; Leukotrienes; Radioimmunoassay; Swine; Thromboxane B2; Thromboxane-A Synthase

1990
Primed stimulation of isolated perfused rabbit lung by endotoxin and platelet activating factor induces enhanced production of thromboxane and lung injury.
    The Journal of clinical investigation, 1990, Volume: 85, Issue:4

    Topics: Animals; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Capillary Permeability; Drug Synergism; Endotoxins; Fatty Acids, Unsaturated; Hydrazines; Imidazoles; In Vitro Techniques; Indomethacin; Lipopolysaccharides; Lung; Perfusion; Platelet Activating Factor; Pulmonary Edema; Rabbits; Thromboxanes; Tumor Necrosis Factor-alpha

1990
Pharmacologic effects on coronary microvessels during myocardial ischaemia.
    European heart journal, 1990, Volume: 11 Suppl B

    Topics: Animals; Blood Flow Velocity; Capillary Permeability; Coronary Circulation; Coronary Disease; Coronary Vessels; Erythrocyte Count; Fatty Acids; Gallopamil; Imidazoles; Indomethacin; Microcirculation; Platelet Count; Rats; Thromboxane-A Synthase; Verapamil

1990
Hydrogen peroxide and methyl mercury are primary stimuli of eicosanoid release in human platelets.
    Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie, 1989, Volume: 27, Issue:9

    Topics: Arachidonic Acids; Aspirin; Blood Platelets; Dose-Response Relationship, Drug; Eicosanoids; Epoprostenol; Humans; Hydrogen Peroxide; Iloprost; Imidazoles; Indomethacin; Methylmercury Compounds; Platelet Aggregation; Serotonin; Thrombin

1989
The inhibition of thromboxane synthesis has no influence on HgCl2-induced acute renal failure in the rat.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1989, Volume: 4, Issue:7

    Topics: Acute Kidney Injury; Animals; Calcium; Glomerular Filtration Rate; Imidazoles; Indomethacin; Male; Mercuric Chloride; Natriuresis; p-Aminohippuric Acid; Rats; Rats, Inbred Strains; Thromboxane-A Synthase; Thromboxanes

1989
Effects of subarachnoid hemorrhage on platelet-derived vasoconstriction of rabbit basilar artery.
    Surgical neurology, 1989, Volume: 32, Issue:6

    Topics: Animals; Basilar Artery; Blood Platelets; Imidazoles; Indomethacin; Isometric Contraction; Ketanserin; Male; Rabbits; Serotonin; Subarachnoid Hemorrhage; Thromboxane A2; Vasoconstriction

1989
Indomethacin, but not dazoxiben, reduced lung fluid filtration after E. coli infusion.
    Journal of applied physiology (Bethesda, Md. : 1985), 1988, Volume: 64, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Body Water; Cardiac Output; Escherichia coli Infections; Imidazoles; Indomethacin; Lung; Lymph; Pulmonary Circulation; Reference Values; Thromboxane B2; Thromboxane-A Synthase

1988
Indomethacin, dazoxiben and extravascular lung water after Escherichia coli infusion.
    The Journal of surgical research, 1986, Volume: 41, Issue:2

    Topics: Animals; Body Water; Cyclooxygenase Inhibitors; Escherichia coli Infections; Female; Imidazoles; Indomethacin; Lung; Male; Prostaglandin-Endoperoxide Synthases; Sepsis; Thromboxane A2

1986
The effect of thromboxane A2 synthesis inhibitors on platelet aggregation in whole blood.
    Thrombosis research, 1987, May-15, Volume: 46, Issue:4

    Topics: Adult; Animals; Arachidonic Acid; Arachidonic Acids; Blood Physiological Phenomena; Collagen; Cyclooxygenase Inhibitors; Humans; Imidazoles; Indomethacin; Male; Mice; Mice, Inbred BALB C; Platelet Aggregation; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Thromboxane A2; Thromboxane-A Synthase

1987
Endothelium-dependent contractions to calcium ionophore A23187, arachidonic acid, and acetylcholine in canine basilar arteries.
    Stroke, 1988, Volume: 19, Issue:4

    Topics: Acetylcholine; Animals; Arachidonic Acid; Arachidonic Acids; Basilar Artery; Calcimycin; Dogs; Endothelium, Vascular; Imidazoles; Indomethacin; Vasoconstriction

1988
Effects of thromboxane A2 on lymphocyte proliferation.
    Cellular immunology, 1985, Volume: 90, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Antibodies, Monoclonal; Cyclooxygenase Inhibitors; Dinoprostone; Humans; Imidazoles; Indomethacin; Lymphocyte Activation; Lymphocytes; Phytohemagglutinins; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandins E; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Thromboxane A2; Thromboxane-A Synthase; Thromboxanes

1985
A comparative study of the involvement of the prostaglandin H2/thromboxane A2 pathway in intravascular platelet aggregation in guinea-pigs and rats.
    British journal of pharmacology, 1985, Volume: 84, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Collagen; Female; Guinea Pigs; Imidazoles; In Vitro Techniques; Indomethacin; Male; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Prostaglandins, Synthetic; Rats; Rats, Inbred Strains; Receptors, Prostaglandin; Receptors, Thromboxane; Species Specificity; Thromboxane A2; Thromboxane B2; Thromboxanes

1985
Raised plasma thromboxane B2 levels in experimental acute necrotizing pancreatitis in rats. The effects of flunarizine, dazoxiben, and indomethacin.
    Scandinavian journal of gastroenterology, 1988, Volume: 23, Issue:2

    Topics: Acute Disease; Animals; Flunarizine; Imidazoles; Indomethacin; Male; Necrosis; Pancreatitis; Rats; Rats, Inbred Strains; Thromboxane A2; Thromboxane B2

1988
Alpha-thrombin-induced pulmonary vasoconstriction.
    Journal of applied physiology (Bethesda, Md. : 1985), 1987, Volume: 63, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Female; Guinea Pigs; Hirudins; Imidazoles; Indomethacin; Lung; Male; Organ Size; Pulmonary Artery; Pulmonary Wedge Pressure; Thrombin; Thromboxane B2; Thromboxane-A Synthase; Vasoconstriction

1987
Inhibition of thromboxane biosynthesis in splanchnic ischemia shock.
    Circulatory shock, 1986, Volume: 18, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Cardiac Output; Dogs; Female; Glucuronidase; Heart Rate; Imidazoles; Indomethacin; Ischemia; Kinetics; Male; Shock; Splanchnic Circulation; Thromboxane B2; Thromboxane-A Synthase; Vascular Resistance

1986
Studies on the role of thromboxane in thrombin-induced pulmonary insufficiency in the rat.
    Thrombosis research, 1986, Apr-15, Volume: 42, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Cattle; Fibrinogen; Fibrinolysis; Imidazoles; Indomethacin; Lung; Lung Diseases; Male; Organ Size; Platelet Count; Rats; Rats, Inbred Strains; Serum Albumin; Thrombin; Thromboxane B2; Thromboxane-A Synthase

1986
Effect of indomethacin and dazoxiben on intravascular platelet aggregation in the anaesthetized rabbit.
    Thrombosis and haemostasis, 1986, Aug-20, Volume: 56, Issue:1

    Topics: Adenosine Diphosphate; Animals; Collagen; Dose-Response Relationship, Drug; Imidazoles; Indomethacin; Male; Platelet Activating Factor; Platelet Aggregation; Rabbits; Thrombin; Thromboxane B2

1986
Regulation of prostaglandin production by osteoblast-rich calvarial cells.
    Prostaglandins, 1985, Volume: 30, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Animals, Newborn; Bradykinin; Cells, Cultured; Dexamethasone; Dinoprostone; Epidermal Growth Factor; Imidazoles; Indomethacin; Osteoblasts; Prostaglandins; Prostaglandins E; Pyrazoles; Pyrazolones; Rats; Thrombin

1985
Thromboxane synthase inhibition potentiates washed platelet activation by endogenous and exogenous arachidonic acid.
    Biochemical pharmacology, 1985, Apr-15, Volume: 34, Issue:8

    Topics: Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Drug Interactions; Humans; Hydrogen Peroxide; Imidazoles; In Vitro Techniques; Indomethacin; Methylmercury Compounds; Oxidoreductases; Platelet Aggregation; Serotonin; Serum Albumin; Sulfonamides; Thromboxane B2; Thromboxane-A Synthase

1985
Leukotriene F4 and the release of arachidonic acid metabolites from perfused guinea pig lungs in vitro.
    Prostaglandins, 1985, Volume: 29, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Biological Assay; Dinoprostone; Female; Guinea Pigs; Imidazoles; In Vitro Techniques; Indomethacin; Lung; Male; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; SRS-A; Thromboxane B2

1985
Inhibition of vasoconstrictor mechanisms by dazoxiben in the rat mesenteric vasculature.
    European journal of pharmacology, 1985, Apr-16, Volume: 110, Issue:3

    Topics: Animals; Cyclooxygenase Inhibitors; Electric Stimulation; Imidazoles; Indomethacin; Male; Norepinephrine; Oxidoreductases; Prazosin; Prostaglandins; Rats; Rats, Inbred Strains; Splanchnic Circulation; Sympathetic Nervous System; Thromboxane-A Synthase; Vasoconstriction; Vasopressins

1985
Inhibition of thromboxane formation prevents endotoxin-induced renal fibrin deposition in jaundiced rats.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1983, Volume: 12

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Endotoxins; Epoprostenol; Fibrin; Imidazoles; Indomethacin; Jaundice; Kidney; Male; Rats; Rats, Inbred Strains; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1983
Effects of thromboxane synthetase inhibition on arachidonate metabolism and platelet behaviour.
    British journal of clinical pharmacology, 1983, Volume: 15 Suppl 1

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Dinoprostone; Epoprostenol; Humans; Imidazoles; In Vitro Techniques; Indomethacin; Oxidoreductases; Platelet Aggregation; Prostaglandins E; Rabbits; Thromboxane B2; Thromboxane-A Synthase

1983
Investigation on a selective non-prostanoic thromboxane antagonist, BM 13.177, in human platelets.
    Thrombosis research, 1984, Feb-01, Volume: 33, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Dose-Response Relationship, Drug; Epinephrine; Humans; Hydrogen Peroxide; Imidazoles; Indomethacin; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandins E; Serotonin; Sulfonamides; Thromboxane A2; Thromboxane B2; Thromboxanes

1984
Thromboxane mediates the increase in alveolar surfactant pool induced by free fatty acid infusion in the rabbit.
    Respiration; international review of thoracic diseases, 1984, Volume: 46, Issue:2

    Topics: Animals; Carbon Dioxide; Cyclooxygenase Inhibitors; Fatty Acids, Nonesterified; Imidazoles; Indomethacin; Lung Compliance; Male; Meclofenamic Acid; Oxygen; Pulmonary Alveoli; Pulmonary Edema; Pulmonary Surfactants; Rabbits; Thromboxane-A Synthase; Thromboxanes

1984
Spasmogenic activity of C5adesArg anaphylatoxin on guinea pig lung parenchymal strips: sensitivity of the leukotriene-mediated component to cyclooxygenase inhibitors.
    Biochemical and biophysical research communications, 1984, Dec-28, Volume: 125, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Complement C5; Complement C5a, des-Arginine; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Guinea Pigs; Imidazoles; Indomethacin; Lung; Muscle Contraction; Piroxicam; Prostaglandins E; Prostaglandins F; SRS-A; Thiazines; Thromboxane B2

1984
Thromboxane-mediated activation of platelets and enhancement of platelet uptake onto collagen-coated glass or deendothelialized rabbit aorta. Comparative effects of a thromboxane antagonist (EPO45) and a thromboxane synthetase inhibitor (dazoxiben).
    Laboratory investigation; a journal of technical methods and pathology, 1984, Volume: 50, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Collagen; Imidazoles; In Vitro Techniques; Indomethacin; Male; Muscle, Smooth, Vascular; Platelet Adhesiveness; Platelet Aggregation; Prostaglandins, Synthetic; Rabbits; Serotonin; Thromboxane B2

1984
RCS from human platelets: is it only thromboxane?
    European journal of pharmacology, 1983, Nov-11, Volume: 95, Issue:1-2

    Topics: Animals; Blood Platelets; Humans; Imidazoles; In Vitro Techniques; Indomethacin; Rabbits; Thromboxane A2; Thromboxane B2; Thromboxanes

1983
In vivo redirection of prostaglandin endoperoxides into 6-keto PGF1 alpha formation by thromboxane synthetase inhibitors in the rat.
    Thrombosis research, 1983, Oct-01, Volume: 32, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Platelets; Collagen; Imidazoles; Indoles; Indomethacin; Male; Oxidoreductases; Pyridines; Radioimmunoassay; Rats; Rats, Inbred Strains; Thrombocytopenia; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1983
Endotoxin, prostaglandins and renal fibrin deposition in obstructive jaundice.
    The British journal of surgery, 1982, Volume: 69, Issue:10

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cholestasis; Endotoxins; Epoprostenol; Escherichia coli; Fibrin; Imidazoles; Indomethacin; Kidney; Male; Prostaglandins; Rats; Rats, Inbred Strains; Thromboxane B2

1982
Endothelium-dependent contractions to endothelin in the rat aorta are mediated by thromboxane A2.
    Journal of cardiovascular pharmacology, 1993, Volume: 22 Suppl 8

    Topics: Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Bridged Bicyclo Compounds, Heterocyclic; Endothelins; Endothelium, Vascular; Fatty Acids, Unsaturated; Hydrazines; Imidazoles; In Vitro Techniques; Indomethacin; Isometric Contraction; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitroarginine; Radioimmunoassay; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Thromboxane A2; Thromboxane-A Synthase

1993
Role of thromboxane A2 in bradykinin-induced human isolated small bronchi contraction.
    European journal of pharmacology, 1995, May-04, Volume: 278, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Aged; Biphenyl Compounds; Bradykinin; Bronchi; Capsaicin; Dose-Response Relationship, Drug; Heptanoic Acids; Humans; Imidazoles; Indomethacin; Male; Middle Aged; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Prostaglandin Endoperoxides, Synthetic; Receptors, Thromboxane; Ruthenium Red; Thromboxane A2; Thromboxane-A Synthase; Vasoconstrictor Agents

1995
Studies on the mechanism of PAF-induced vasopermeability in rat lungs.
    Prostaglandins, leukotrienes, and essential fatty acids, 1995, Volume: 52, Issue:4

    Topics: Animals; Blood Proteins; Bronchi; Capillary Permeability; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Imidazoles; Indomethacin; Lung; Male; Platelet Activating Factor; Quinacrine; Rats; Rats, Wistar; Trachea

1995
Platelet activation induced by interleukin-6: evidence for a mechanism involving arachidonic acid metabolism.
    Thrombosis and haemostasis, 1994, Volume: 72, Issue:2

    Topics: Adenosine Diphosphate; Arachidonic Acid; beta-Thromboglobulin; Blood Platelets; Calcimycin; Cytoskeleton; Drug Synergism; Humans; Imidazoles; Indomethacin; Interleukin-6; Platelet Activation; Prostaglandin-Endoperoxide Synthases; Recombinant Proteins; Thromboxane B2

1994
Spontaneously hypertensive versus control rat aorta response to neutrophil-derived factors.
    Hypertension (Dallas, Tex. : 1979), 1994, Volume: 24, Issue:6

    Topics: Animals; Aorta; Imidazoles; In Vitro Techniques; Indomethacin; Male; Neutrophils; Pentanoic Acids; Pyridines; Rats; Rats, Inbred SHR; Rats, Wistar; Superoxide Dismutase; Superoxides; Thromboxane-A Synthase

1994
Contractile effect of endothelin in human placental veins: role of endothelium prostaglandins and thromboxane.
    American journal of obstetrics and gynecology, 1993, Volume: 169, Issue:4

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Bridged Bicyclo Compounds, Heterocyclic; Endothelins; Endothelium, Vascular; Fatty Acids, Unsaturated; Female; Humans; Hydrazines; Imidazoles; In Vitro Techniques; Indomethacin; Placenta; Pregnancy; Prostaglandin Endoperoxides, Synthetic; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Thromboxane A2; Thromboxane-A Synthase; Vasoconstriction; Vasoconstrictor Agents; Veins

1993
Products of cyclooxygenase mediate the responses of the guinea pig trachea to hydrogen peroxide.
    Journal of applied physiology (Bethesda, Md. : 1985), 1993, Volume: 74, Issue:5

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Bridged Bicyclo Compounds, Heterocyclic; Epithelium; Fatty Acids, Unsaturated; Guinea Pigs; Hydrazines; Hydrogen Peroxide; Imidazoles; In Vitro Techniques; Indomethacin; Isometric Contraction; Male; Muscle Contraction; Muscle, Smooth; Prostaglandin Endoperoxides, Synthetic; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Radioimmunoassay; Receptors, Thromboxane; Thromboxane-A Synthase; Trachea; Vasoconstrictor Agents

1993
Angiotensin II-induced contractions in human internal mammary artery: effects of cyclooxygenase and lipoxygenase inhibition.
    Cardiovascular research, 2000, Volume: 47, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Angiotensin II; Benzoquinones; Biphenyl Compounds; Cyclooxygenase Inhibitors; Depression, Chemical; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavanones; Flavonoids; Heptanoic Acids; Humans; Imidazoles; In Vitro Techniques; Indomethacin; Leukotrienes; Lipoxygenase Inhibitors; Mammary Arteries; Propionates; Pyrazoles; Quinolines; Receptors, Thromboxane; Substance P; Thromboxane B2; Thromboxane-A Synthase; Vasoconstriction

2000
Endothelin-1 releases endothelium-derived endoperoxides and thromboxane A2 in porcine coronary arteries with regenerated endothelium.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1999, Volume: 20, Issue:10

    Topics: Animals; Coronary Vessels; Cyclooxygenase Inhibitors; Endothelin-1; Endothelium, Vascular; Imidazoles; Indomethacin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroarginine; Pentanoic Acids; Pyridines; Swine; Thromboxane A2; Thromboxane-A Synthase

1999
Thromboxane synthase regulates the migratory phenotype of human glioma cells.
    Neuro-oncology, 1999, Volume: 1, Issue:1

    Topics: Arachidonic Acids; Aspirin; Astrocytes; Benzofurans; Brain Neoplasms; Cell Adhesion; Cell Movement; Enzyme Induction; Enzyme Inhibitors; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioma; GTP-Binding Proteins; Humans; Imidazoles; Indomethacin; Lysine; Models, Biological; Neoplasm Proteins; Neoplastic Stem Cells; Oligodendroglia; Pentanoic Acids; Phenotype; Pyridines; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Thromboxane B2; Thromboxane-A Synthase; Tumor Cells, Cultured

1999
Sexual dimorphism in prostanoid-potentiated vascular contraction: roles of endothelium and ovarian steroids.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 283, Issue:5

    Topics: Animals; Aorta; Bridged Bicyclo Compounds, Heterocyclic; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Estrogens; Fatty Acids, Unsaturated; Female; Hydrazines; Imidazoles; Indomethacin; Male; Ovariectomy; Phenylephrine; Progesterone; Prostaglandins; Rats; Rats, Sprague-Dawley; Sex Characteristics; Thromboxanes; Vasoconstriction; Vasoconstrictor Agents; Vasopressins

2002
Study of the mechanisms involved in the bradykinin-induced contraction of the pig iris sphincter muscle in vitro.
    European journal of pharmacology, 2003, Jan-01, Volume: 458, Issue:1-2

    Topics: Animals; Atropine; Bradykinin; Bradykinin Receptor Antagonists; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanethidine; Ibuprofen; Imidazoles; In Vitro Techniques; Indomethacin; Iris; Kallidin; Muscle Contraction; Muscle, Smooth; Nitrobenzenes; Propionates; Quinolines; Salicylates; Sulfonamides; Swine; Tetrodotoxin; Thromboxane-A Synthase

2003
BK2 but not BK1 receptors mediating contractile response in human umbilical arteries: role of thromboxane A2.
    Methods and findings in experimental and clinical pharmacology, 2004, Volume: 26, Issue:4

    Topics: Bradykinin; Bradykinin B1 Receptor Antagonists; Bradykinin B2 Receptor Antagonists; Dose-Response Relationship, Drug; Endothelium; Humans; Imidazoles; Indomethacin; Masoprocol; Muscle Contraction; Muscle, Smooth, Vascular; Quinacrine; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Thromboxane A2; Umbilical Arteries

2004
Acetylcholine-induced endothelium-dependent contractions in the SHR aorta: the Janus face of prostacyclin.
    British journal of pharmacology, 2005, Volume: 146, Issue:6

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Aorta, Thoracic; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Hypertension; Imidazoles; In Vitro Techniques; Indomethacin; Nitrobenzenes; Prostaglandins; Prostaglandins I; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Salicylates; Sulfonamides; Thromboxane A2; Vasoconstriction; Vasoconstrictor Agents

2005
Role of superoxide and thromboxane receptors in acute angiotensin II-induced vasoconstriction of rabbit vessels.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 300, Issue:6

    Topics: Angiotensin II; Animals; Aorta, Thoracic; Arachidonic Acid; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Imidazoles; Indomethacin; Isoprostanes; Male; Mesenteric Arteries; Models, Animal; Muscle, Smooth, Vascular; Rabbits; Receptors, Thromboxane; Superoxides; Vasoconstriction; Vasoconstrictor Agents

2011
Pulmonary arterial responses to reactive oxygen species are altered in newborn piglets with chronic hypoxia-induced pulmonary hypertension.
    Pediatric research, 2011, Volume: 70, Issue:2

    Topics: Animals; Animals, Newborn; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme System; Enzyme-Linked Immunosorbent Assay; Hypertension, Pulmonary; Hypoxia; Imidazoles; Immunoblotting; Indomethacin; Intramolecular Oxidoreductases; Prostaglandins; Pulmonary Artery; Reactive Oxygen Species; Statistics, Nonparametric; Sus scrofa; Thromboxane-A Synthase; Vasoconstriction

2011