Page last updated: 2024-08-23

dazoxiben and arachidonic acid

dazoxiben has been researched along with arachidonic acid in 47 studies

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-199038 (80.85)18.7374
1990's6 (12.77)18.2507
2000's2 (4.26)29.6817
2010's1 (2.13)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ernst, A; Mest, HJ; Syka, J1
Arreto, CD; Bureau, MF; De Clerck, F; Lefort, J; Vargaftig, BB1
Chen, XS; Fu, CD; Huang, TG; Jiang, YY; Liao, LM; Long, K1
Lin, AY; Rui, YC; Sun, DX1
Hornberger, W; Patscheke, H1
Arnout, J; Deckmyn, H; Gresele, P; Nenci, GG; Vermylen, J1
Darius, H; Lefer, AM1
Arnout, J; Deckmyn, H; Gresele, P; Huybrechts, E; Pieters, G; Vermylen, J1
Carmo, LG; Hatmi, M; Rotilio, D; Vargaftig, BB1
Heptinstall, S; Sills, T1
Antonicelli, F; Hatmi, M; Haye, B; Joseph, D; Rotilio, D; Vargaftig, BB1
Bonne, C; Coquelet, C; Sincholle, D1
Ghai, R; Lindsay, LA; Olson, RW; Sakane, Y; Smith, EF1
Lad, N; Lunt, DO; Tuffin, DP1
Katusic, ZS; Shepherd, JT; Vanhoutte, PM1
Blockmans, D; Deckmyn, H; Gresele, P; Vermylen, J1
Andries, R; Bourgain, RH; Braquet, P; Decuyper, K1
Cassina, G; Livio, M; Macconi, D; Morelli, C; Morzenti, G; Remuzzi, G1
Ettinger, WH; Malamet, R; Wigley, FM; Wise, RA1
Bertelé, V; Castagnoli, MN; Cerletti, C; de Gaetano, G; Rajtar, G1
Patscheke, H1
Charleson, S; Letts, LG; Lord, A1
Greenberg, R; Liu, EC; O'Keefe, EH; Ogletree, ML1
Crawford, J; Heptinstall, S; MacPherson, M; Morrison, R1
Carter, AJ; Heptinstall, S1
Lefer, AM; Nicolaou, KC; Smith, EF; Smith, JB1
Parry, MJ1
Fox, SC; Heptinstall, S1
Cockbill, SR; Cowley, AJ; Hanley, SP; Heptinstall, S; Jones, EW1
Lefer, AM; Lefer, BL; Reibel, DK; Roth, DM1
Randall, MJ1
Lucchesi, BR; Schumacher, WA1
Burke, SE; Lefer, AM; Smith, JB1
Patscheke, H; Stegmeier, K1
Bertelé, V; Cerletti, C; Chiabrando, C; de Gaetano, G; Falanga, A; Tomasiak, M1
Garcia, G; Luderer, JR; Neumyer, MM; Nicholas, GG; Riley, DL; Schneck, DW; Vary, JE1
Deckmyn, H; Gresele, P; Huybrechts, E; Vermylen, J1
Brash, A; Fitzgerald, G; Oates, JA1
Castagnoli, MN; Cerletti, C; Chiabrando, C; de Gaetano, G; Fanelli, R; Noseda, A; Rajtar, G1
Bertelé, V; Cerletti, C; de Gaetano, G; Rajtar, G1
Lefer, AM; Okamatsu, S; Smith, EF; Smith, JB1
Bertelé, V; Cerletti, C; de Gaetano, G; Di Minno, G; Silver, MJ1
Dutcher, J; Isaacs, R; Mrowiec, Z; Oleksowicz, L; Puszkin, E; Zuckerman, D1
Chang, SW; Ohara, N; Voelkel, NF1
Audoly, LP; Carty, TJ; Eskra, JD; Perez, JR; Trebino, CE; Wachtmann, TS1
Rudzevich, AJ; Shapovalova, EM1
Campbell, WB; Nithipatikom, K; Pfister, SL1

Reviews

1 review(s) available for dazoxiben and arachidonic acid

ArticleYear
Selective inhibition of thromboxane synthesis with dazoxiben in animals and man.
    Thrombosis research. Supplement, 1983, Volume: 4

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Fibrinolytic Agents; Humans; Imidazoles; Microsomes; Platelet Aggregation; Sheep; Swine; Thromboxane B2; Thromboxanes

1983

Trials

2 trial(s) available for dazoxiben and arachidonic acid

ArticleYear
Role of proaggregatory and antiaggregatory prostaglandins in hemostasis. Studies with combined thromboxane synthase inhibition and thromboxane receptor antagonism.
    The Journal of clinical investigation, 1987, Volume: 80, Issue:5

    Topics: Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Bleeding Time; Cyclooxygenase Inhibitors; Hemostasis; Humans; Imidazoles; Indomethacin; Male; Platelet Aggregation; Prostaglandins; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Thromboxane-A Synthase

1987
Nifedipine in the treatment of Raynaud's phenomenon. Evidence for inhibition of platelet activation.
    The American journal of medicine, 1985, Volume: 78, Issue:4

    Topics: Adult; Arachidonic Acid; Arachidonic Acids; beta-Thromboglobulin; Blood Platelets; Double-Blind Method; Female; Humans; Imidazoles; Male; Middle Aged; Nifedipine; Placebos; Platelet Factor 4; Raynaud Disease; Thromboxane-A Synthase

1985

Other Studies

44 other study(ies) available for dazoxiben and arachidonic acid

ArticleYear
Electrophysiological responses of the cochlea to transient asphyxia are influenced by arachidonate metabolites.
    Prostaglandins, 1992, Volume: 43, Issue:4

    Topics: Analysis of Variance; Animals; Arachidonic Acid; Cochlear Diseases; Epoprostenol; Female; Guinea Pigs; Imidazoles; Male; Phenylacetates; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Thromboxane A2; Thromboxane-A Synthase; Time Factors

1992
Thromboxane A2 accounts for bronchoconstriction but not for platelet sequestration and microvascular albumin exchanges induced by fMLP in the guinea pig lung.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Blood Platelets; Bronchoconstriction; Guinea Pigs; Imidazoles; Lung; N-Formylmethionine Leucyl-Phenylalanine; Pentanoic Acids; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Pyridines; Radioimmunoassay; Serum Albumin; Suprofen; Thrombocytopenia; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Tretoquinol

1992
Effects of CI-930 on hemostasis, thrombosis, and AA-induced hemodynamic reaction.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1991, Volume: 12, Issue:4

    Topics: Animals; Arachidonic Acid; Bleeding Time; Cardiotonic Agents; Hemodynamics; Hemostasis; Imidazoles; Male; Mice; Pulmonary Embolism; Pyridazines; Rabbits; Rats; Rats, Inbred Strains; Thrombosis; Thromboxane-A Synthase

1991
[Effect of dazoxiben on the metabolism of arachidonic acid in isolated porcine basilar arteries].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1990, Volume: 11, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Basilar Artery; Biological Assay; Imidazoles; In Vitro Techniques; Indomethacin; Leukotrienes; Radioimmunoassay; Swine; Thromboxane B2; Thromboxane-A Synthase

1990
Transient concentrations and agonist potency of PGH2 in platelet activation by endogenous arachidonate.
    Eicosanoids, 1989, Volume: 2, Issue:4

    Topics: Arachidonic Acid; Arachidonic Acids; Blood Platelets; Humans; Imidazoles; In Vitro Techniques; Methylmercury Compounds; Platelet Activation; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Serotonin; Thrombin; Thromboxane A2; Thromboxane-A Synthase

1989
Characterization of N,N'-bis(3-picolyl)-4-methoxy-isophtalamide (picotamide) as a dual thromboxane synthase inhibitor/thromboxane A2 receptor antagonist in human platelets.
    Thrombosis and haemostasis, 1989, Jun-30, Volume: 61, Issue:3

    Topics: Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cyclic AMP; Fibrinolytic Agents; Humans; Imidazoles; Phthalic Acids; Platelet Aggregation Inhibitors; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Thromboxane-A Synthase; Thromboxanes

1989
Antiaggregatory effects of thromboxane receptor antagonists in vivo.
    Thrombosis research, 1985, Dec-01, Volume: 40, Issue:5

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Triphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Collagen; Fatty Acids, Unsaturated; Fibrinolytic Agents; Hydrazines; Imidazoles; Kinetics; Male; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Rabbits; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Thromboxane-A Synthase; Thromboxanes

1985
Platelet desensitization induced by arachidonic acid is not due to cyclo-oxygenase inactivation and involves the endoperoxide receptor.
    British journal of pharmacology, 1985, Volume: 85, Issue:4

    Topics: Adenosine Triphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cyclooxygenase Inhibitors; Humans; Imidazoles; Indoles; Microscopy, Electron; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Receptors, Cell Surface; Receptors, Prostaglandin; Receptors, Thromboxane; Salicylates; Thrombin; Thromboxane B2

1985
Effects of a thromboxane synthetase inhibitor and a cAMP phosphodiesterase inhibitor, singly and in combination, on platelet behaviour.
    Thrombosis and haemostasis, 1986, Jun-30, Volume: 55, Issue:3

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cyclic AMP; Drug Interactions; Humans; Imidazoles; In Vitro Techniques; Platelet Aggregation; Serotonin; Thromboxane-A Synthase

1986
Modulation by cyclic AMP of arachidonic acid-induced platelet desensitization.
    European journal of pharmacology, 1986, Dec-16, Volume: 132, Issue:2-3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenylyl Cyclases; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Bucladesine; Cyclic AMP; Humans; Imidazoles; In Vitro Techniques; Prostaglandin Endoperoxides, Synthetic; Thromboxane B2

1986
Inhibition of platelet thromboxane synthetase by 1-(3-benzyloxy-1[E]octenyl)imidazole.
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:1

    Topics: Adult; Animals; Arachidonic Acid; Arachidonic Acids; Bleeding Time; Blood Platelets; Dinoprostone; Humans; Imidazoles; In Vitro Techniques; Male; Middle Aged; Prostaglandins E; Rabbits; Rats; Rats, Inbred Strains; Thrombosis; Thromboxane B2; Thromboxane-A Synthase

1986
Dazoxiben, UK 38,485 and aspirin: duration of effect for preventing thrombotic sudden death in rabbits.
    Thrombosis research, 1986, Jul-15, Volume: 43, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Imidazoles; Male; Rabbits; Thrombocytopenia; Thrombosis; Thromboxane B2; Time Factors

1986
The effect of thromboxane A2 synthesis inhibitors on platelet aggregation in whole blood.
    Thrombosis research, 1987, May-15, Volume: 46, Issue:4

    Topics: Adult; Animals; Arachidonic Acid; Arachidonic Acids; Blood Physiological Phenomena; Collagen; Cyclooxygenase Inhibitors; Humans; Imidazoles; Indomethacin; Male; Mice; Mice, Inbred BALB C; Platelet Aggregation; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Thromboxane A2; Thromboxane-A Synthase

1987
Endothelium-dependent contractions to calcium ionophore A23187, arachidonic acid, and acetylcholine in canine basilar arteries.
    Stroke, 1988, Volume: 19, Issue:4

    Topics: Acetylcholine; Animals; Arachidonic Acid; Arachidonic Acids; Basilar Artery; Calcimycin; Dogs; Endothelium, Vascular; Imidazoles; Indomethacin; Vasoconstriction

1988
Adenylate cyclase activation determines the effect of thromboxane synthase inhibitors on platelet aggregation in vitro. Comparison of platelets from responders and nonresponders.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:1

    Topics: Adenylyl Cyclases; Adult; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Dinoprostone; Eicosanoic Acids; Enzyme Activation; Female; Humans; Imidazoles; Indoles; Male; Methacrylates; Middle Aged; Platelet Aggregation; Prostaglandins E; Pyridines; Thromboxane-A Synthase

1988
Exchange of cyclooxygenase dependent metabolites between vessel wall and platelets in arterial thrombosis.
    Thrombosis research, 1988, May-01, Volume: 50, Issue:3

    Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Epoprostenol; Imidazoles; Male; Mesenteric Arteries; Platelet Aggregation; Propionates; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains; Thrombosis; Thromboxane A2; Tranylcypromine

1988
Acetyl glycerylphosphorylcholine aggregates human platelets through two distinct pathways, both dependent on arachidonic acid metabolism.
    Laboratory investigation; a journal of technical methods and pathology, 1985, Volume: 52, Issue:2

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Catechols; Chromatography, Thin Layer; Cyclooxygenase Inhibitors; Humans; Imidazoles; In Vitro Techniques; Lipoxygenase Inhibitors; Masoprocol; Phospholipases; Platelet Activating Factor; Platelet Aggregation; Prostanoic Acids; Quinacrine; Radioimmunoassay; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxane A2; Thromboxane-A Synthase

1985
Prostaglandins and human platelet aggregation. Implications for the anti-aggregating activity of thromboxane-synthase inhibitors.
    Biochemical pharmacology, 1985, Feb-01, Volume: 34, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Dinoprost; Dinoprostone; Drug Synergism; Humans; Imidazoles; Oxidoreductases; Platelet Aggregation; Prostaglandin D2; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandins; Prostaglandins D; Prostaglandins E; Prostaglandins F; Prostanoic Acids; Thromboxane B2; Thromboxane-A Synthase

1985
Thromboxane synthase inhibition potentiates washed platelet activation by endogenous and exogenous arachidonic acid.
    Biochemical pharmacology, 1985, Apr-15, Volume: 34, Issue:8

    Topics: Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Drug Interactions; Humans; Hydrogen Peroxide; Imidazoles; In Vitro Techniques; Indomethacin; Methylmercury Compounds; Oxidoreductases; Platelet Aggregation; Serotonin; Serum Albumin; Sulfonamides; Thromboxane B2; Thromboxane-A Synthase

1985
Leukotriene F4 and the release of arachidonic acid metabolites from perfused guinea pig lungs in vitro.
    Prostaglandins, 1985, Volume: 29, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Biological Assay; Dinoprostone; Female; Guinea Pigs; Imidazoles; In Vitro Techniques; Indomethacin; Lung; Male; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; SRS-A; Thromboxane B2

1985
Effects of a thromboxane synthetase inhibitor and a thromboxane antagonist on release and activity of thromboxane A2 and prostacyclin in vitro.
    Prostaglandins, 1985, Volume: 29, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Epoprostenol; Fatty Acids, Unsaturated; Guinea Pigs; Hydrazines; Imidazoles; Male; Muscle Contraction; Muscle, Smooth, Vascular; Oxidoreductases; Rats; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1985
Platelet behaviour in normal pregnancy, pregnancy complicated by essential hypertension and pregnancy-induced hypertension.
    Thrombosis and haemostasis, 1985, Oct-30, Volume: 54, Issue:3

    Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Epinephrine; Female; Humans; Hypertension; Imidazoles; Platelet Aggregation; Pregnancy; Pregnancy Complications, Cardiovascular; Serotonin

1985
Platelet aggregation in whole blood: the role of thromboxane A2 and adenosine diphosphate.
    Thrombosis and haemostasis, 1985, Oct-30, Volume: 54, Issue:3

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adenosine Diphosphate; Apyrase; Arachidonic Acid; Arachidonic Acids; Aspirin; Collagen; Cyclooxygenase Inhibitors; Epinephrine; Flurbiprofen; Humans; Imidazoles; In Vitro Techniques; Lipoxygenase Inhibitors; Platelet Aggregation; Pyrazoles; Thrombin; Thromboxane A2; Thromboxane-A Synthase

1985
Thromboxane synthetase inhibitors differentially antagonize thromboxane receptors in vascular smooth muscle.
    Naunyn-Schmiedeberg's archives of pharmacology, 1981, Volume: 318, Issue:2

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bicyclic Monoterpenes; Blood Platelets; Cats; Coronary Vessels; Imidazoles; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Oxidoreductases; Pulmonary Artery; Receptors, Cell Surface; Receptors, Prostaglandin; Receptors, Thromboxane; Serotonin; Thromboxane A2; Thromboxane-A Synthase

1981
Effects of thromboxane synthetase inhibition on arachidonate metabolism and platelet behaviour.
    British journal of clinical pharmacology, 1983, Volume: 15 Suppl 1

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Dinoprostone; Epoprostenol; Humans; Imidazoles; In Vitro Techniques; Indomethacin; Oxidoreductases; Platelet Aggregation; Prostaglandins E; Rabbits; Thromboxane B2; Thromboxane-A Synthase

1983
Human blood platelet behaviour after inhibition of thromboxane synthetase.
    British journal of clinical pharmacology, 1983, Volume: 15 Suppl 1

    Topics: Arachidonic Acid; Arachidonic Acids; Blood Platelets; Humans; Imidazoles; In Vitro Techniques; Malondialdehyde; Oxidoreductases; Serotonin; Thromboxane A2; Thromboxane-A Synthase

1983
Effects of dazoxiben and low-dose aspirin on platelet behaviour in man.
    British journal of clinical pharmacology, 1983, Volume: 15 Suppl 1

    Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Epinephrine; Female; Humans; Imidazoles; Male; Oxidoreductases; Thromboxane-A Synthase

1983
Hyperreactivity of coronary vasculature in platelet-perfused hearts from diabetic rats.
    The American journal of physiology, 1983, Volume: 245, Issue:4

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cats; Coronary Circulation; Diabetes Mellitus, Experimental; Heart; Ibuprofen; Imidazoles; Male; Perfusion; Prostaglandins; Rats; Rats, Inbred Strains; Thromboxane-A Synthase

1983
Effect of the thromboxane synthetase inhibitor UK-37,248 (dazoxiben) upon platelet aggregation, coronary artery thrombosis and vascular reactivity.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 227, Issue:3

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Coronary Circulation; Coronary Disease; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Hyperemia; Imidazoles; Male; Oxidoreductases; Platelet Aggregation; Thromboxane B2; Thromboxane-A Synthase; Time Factors; Vasodilation

1983
Role of thromboxanes and prostaglandin endoperoxides in the pathogenesis of eicosanoid induced sudden death.
    Thrombosis research, 1983, Nov-01, Volume: 32, Issue:3

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Death, Sudden; Imidazoles; Male; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandins H; Pulmonary Embolism; Rabbits; Thromboxane A2; Thromboxanes; Vasoconstriction

1983
Investigation on a selective non-prostanoic thromboxane antagonist, BM 13.177, in human platelets.
    Thrombosis research, 1984, Feb-01, Volume: 33, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Dose-Response Relationship, Drug; Epinephrine; Humans; Hydrogen Peroxide; Imidazoles; Indomethacin; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandins E; Serotonin; Sulfonamides; Thromboxane A2; Thromboxane B2; Thromboxanes

1984
Pharmacologic inhibition of thromboxane synthetase and platelet aggregation: modulatory role of cyclooxygenase products.
    Blood, 1984, Volume: 63, Issue:6

    Topics: Adult; Arachidonic Acid; Arachidonic Acids; Chromatography, Gas; Chromatography, Thin Layer; Dinoprost; Dinoprostone; Female; Humans; Imidazoles; Male; Mass Spectrometry; Oxidoreductases; Platelet Aggregation; Prostaglandin D2; Prostaglandins D; Prostaglandins E; Prostaglandins F; Radioimmunoassay; Thromboxane A2; Thromboxane-A Synthase; Thromboxanes

1984
Dazoxiben, a thromboxane synthetase inhibitor, in Raynaud's phenomenon.
    Clinical pharmacology and therapeutics, 1984, Volume: 36, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Arachidonic Acid; Arachidonic Acids; Double-Blind Method; Drug Evaluation; Female; Forearm; Humans; Imidazoles; Male; Middle Aged; Plethysmography; Radioimmunoassay; Raynaud Disease; Thromboxane B2

1984
Serum albumin enhances the impairment of platelet aggregation with thromboxane synthase inhibition by increasing the formation of prostaglandin D2.
    Biochemical pharmacology, 1984, Jul-01, Volume: 33, Issue:13

    Topics: Adenine; Adult; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Female; Humans; Imidazoles; Male; Middle Aged; Oxidoreductases; Platelet Aggregation; Prostaglandin D2; Prostaglandins D; Serum Albumin; Thromboxane-A Synthase

1984
Comparison of the effects of selective inhibition of thromboxane synthase with those of inhibition of the cyclooxygenase enzyme in man.
    Transactions of the American Clinical and Climatological Association, 1984, Volume: 95

    Topics: 6-Ketoprostaglandin F1 alpha; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Imidazoles; Male; Oxidoreductases; Pyridines; Thromboxane-A Synthase; Time Factors

1984
Comparison of radioimmunoassay and high-resolution gas chromatography mass spectrometry for the quantitative determination of serum thromboxane B2 and 6-keto-PGF1 alpha after pharmacological blockade of thromboxane synthetase.
    Prostaglandins, leukotrienes, and medicine, 1984, Volume: 16, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Arachidonic Acid; Arachidonic Acids; Gas Chromatography-Mass Spectrometry; Humans; Imidazoles; In Vitro Techniques; Oxidoreductases; Radioimmunoassay; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1984
Inhibition of arachidonate-induced human platelet aggregation by a single low oral dose of aspirin in combination with a thromboxane synthase inhibitor.
    Thrombosis and haemostasis, 1984, Oct-31, Volume: 52, Issue:2

    Topics: Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Female; Humans; Imidazoles; Male; Oxidoreductases; Platelet Aggregation; Thromboxane-A Synthase

1984
Beneficial effects of a new thromboxane synthetase inhibitor in arachidonate-induced sudden death.
    Thrombosis research, 1981, Aug-01, Volume: 23, Issue:3

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Death, Sudden; Electrocardiography; Heart Rate; Imidazoles; Male; Oxidoreductases; Prostaglandins F; Pulmonary Artery; Rabbits; Serotonin; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Vasoconstrictor Agents

1981
Arachidonic acid induces human platelet-fibrin retraction: the role of platelet cyclic endoperoxides.
    Thrombosis research, 1982, Feb-15, Volume: 25, Issue:4

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alprostadil; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Clot Retraction; Epoprostenol; Fatty Acids, Unsaturated; Fibrin; Humans; Imidazoles; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandins D; Prostaglandins E; Prostaglandins H; Prostaglandins, Synthetic; Thromboxane B2

1982
Platelet activation induced by interleukin-6: evidence for a mechanism involving arachidonic acid metabolism.
    Thrombosis and haemostasis, 1994, Volume: 72, Issue:2

    Topics: Adenosine Diphosphate; Arachidonic Acid; beta-Thromboglobulin; Blood Platelets; Calcimycin; Cytoskeleton; Drug Synergism; Humans; Imidazoles; Indomethacin; Interleukin-6; Platelet Activation; Prostaglandin-Endoperoxide Synthases; Recombinant Proteins; Thromboxane B2

1994
Tissue eicosanoids and vascular permeability in rats with chronic biliary obstruction.
    Hepatology (Baltimore, Md.), 1993, Volume: 18, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Bile Ducts; Capillary Permeability; Cholestasis; Eicosanoids; Imidazoles; Kidney; Ligation; Liver Cirrhosis, Biliary; Lung; Male; Rats; Rats, Sprague-Dawley; Serum Albumin, Radio-Iodinated; Thromboxane A2; Thromboxane B2

1993
Redirection of eicosanoid metabolism in mPGES-1-deficient macrophages.
    The Journal of biological chemistry, 2005, Apr-29, Volume: 280, Issue:17

    Topics: Animals; Arachidonic Acid; Blotting, Western; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Eicosanoids; Fatty Acids, Unsaturated; Genotype; Imidazoles; Inflammation; Intramolecular Oxidoreductases; Kinetics; Lipopolysaccharides; Macrophages; Mice; Mice, Transgenic; Microsomes; Prostaglandin-E Synthases; Prostaglandins; Thioglycolates; Thromboxane B2; Time Factors

2005
Effect of inhibitors of arachidonic acid conversion in platelets on thrombin-fibrinogen interaction and thrombin tolerance.
    Bulletin of experimental biology and medicine, 2007, Volume: 144, Issue:4

    Topics: Animals; Arachidonic Acid; Aspirin; Blood Platelets; Dose-Response Relationship, Drug; Fibrinogen; Imidazoles; Male; Platelet Aggregation; Quinacrine; Rats; Thrombin

2007
Role of superoxide and thromboxane receptors in acute angiotensin II-induced vasoconstriction of rabbit vessels.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 300, Issue:6

    Topics: Angiotensin II; Animals; Aorta, Thoracic; Arachidonic Acid; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Imidazoles; Indomethacin; Isoprostanes; Male; Mesenteric Arteries; Models, Animal; Muscle, Smooth, Vascular; Rabbits; Receptors, Thromboxane; Superoxides; Vasoconstriction; Vasoconstrictor Agents

2011