dazoxiben has been researched along with arachidonic acid in 47 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 38 (80.85) | 18.7374 |
1990's | 6 (12.77) | 18.2507 |
2000's | 2 (4.26) | 29.6817 |
2010's | 1 (2.13) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Ernst, A; Mest, HJ; Syka, J | 1 |
Arreto, CD; Bureau, MF; De Clerck, F; Lefort, J; Vargaftig, BB | 1 |
Chen, XS; Fu, CD; Huang, TG; Jiang, YY; Liao, LM; Long, K | 1 |
Lin, AY; Rui, YC; Sun, DX | 1 |
Hornberger, W; Patscheke, H | 1 |
Arnout, J; Deckmyn, H; Gresele, P; Nenci, GG; Vermylen, J | 1 |
Darius, H; Lefer, AM | 1 |
Arnout, J; Deckmyn, H; Gresele, P; Huybrechts, E; Pieters, G; Vermylen, J | 1 |
Carmo, LG; Hatmi, M; Rotilio, D; Vargaftig, BB | 1 |
Heptinstall, S; Sills, T | 1 |
Antonicelli, F; Hatmi, M; Haye, B; Joseph, D; Rotilio, D; Vargaftig, BB | 1 |
Bonne, C; Coquelet, C; Sincholle, D | 1 |
Ghai, R; Lindsay, LA; Olson, RW; Sakane, Y; Smith, EF | 1 |
Lad, N; Lunt, DO; Tuffin, DP | 1 |
Katusic, ZS; Shepherd, JT; Vanhoutte, PM | 1 |
Blockmans, D; Deckmyn, H; Gresele, P; Vermylen, J | 1 |
Andries, R; Bourgain, RH; Braquet, P; Decuyper, K | 1 |
Cassina, G; Livio, M; Macconi, D; Morelli, C; Morzenti, G; Remuzzi, G | 1 |
Ettinger, WH; Malamet, R; Wigley, FM; Wise, RA | 1 |
Bertelé, V; Castagnoli, MN; Cerletti, C; de Gaetano, G; Rajtar, G | 1 |
Patscheke, H | 1 |
Charleson, S; Letts, LG; Lord, A | 1 |
Greenberg, R; Liu, EC; O'Keefe, EH; Ogletree, ML | 1 |
Crawford, J; Heptinstall, S; MacPherson, M; Morrison, R | 1 |
Carter, AJ; Heptinstall, S | 1 |
Lefer, AM; Nicolaou, KC; Smith, EF; Smith, JB | 1 |
Parry, MJ | 1 |
Fox, SC; Heptinstall, S | 1 |
Cockbill, SR; Cowley, AJ; Hanley, SP; Heptinstall, S; Jones, EW | 1 |
Lefer, AM; Lefer, BL; Reibel, DK; Roth, DM | 1 |
Randall, MJ | 1 |
Lucchesi, BR; Schumacher, WA | 1 |
Burke, SE; Lefer, AM; Smith, JB | 1 |
Patscheke, H; Stegmeier, K | 1 |
Bertelé, V; Cerletti, C; Chiabrando, C; de Gaetano, G; Falanga, A; Tomasiak, M | 1 |
Garcia, G; Luderer, JR; Neumyer, MM; Nicholas, GG; Riley, DL; Schneck, DW; Vary, JE | 1 |
Deckmyn, H; Gresele, P; Huybrechts, E; Vermylen, J | 1 |
Brash, A; Fitzgerald, G; Oates, JA | 1 |
Castagnoli, MN; Cerletti, C; Chiabrando, C; de Gaetano, G; Fanelli, R; Noseda, A; Rajtar, G | 1 |
Bertelé, V; Cerletti, C; de Gaetano, G; Rajtar, G | 1 |
Lefer, AM; Okamatsu, S; Smith, EF; Smith, JB | 1 |
Bertelé, V; Cerletti, C; de Gaetano, G; Di Minno, G; Silver, MJ | 1 |
Dutcher, J; Isaacs, R; Mrowiec, Z; Oleksowicz, L; Puszkin, E; Zuckerman, D | 1 |
Chang, SW; Ohara, N; Voelkel, NF | 1 |
Audoly, LP; Carty, TJ; Eskra, JD; Perez, JR; Trebino, CE; Wachtmann, TS | 1 |
Rudzevich, AJ; Shapovalova, EM | 1 |
Campbell, WB; Nithipatikom, K; Pfister, SL | 1 |
1 review(s) available for dazoxiben and arachidonic acid
Article | Year |
---|---|
Selective inhibition of thromboxane synthesis with dazoxiben in animals and man.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Fibrinolytic Agents; Humans; Imidazoles; Microsomes; Platelet Aggregation; Sheep; Swine; Thromboxane B2; Thromboxanes | 1983 |
2 trial(s) available for dazoxiben and arachidonic acid
Article | Year |
---|---|
Role of proaggregatory and antiaggregatory prostaglandins in hemostasis. Studies with combined thromboxane synthase inhibition and thromboxane receptor antagonism.
Topics: Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Bleeding Time; Cyclooxygenase Inhibitors; Hemostasis; Humans; Imidazoles; Indomethacin; Male; Platelet Aggregation; Prostaglandins; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Thromboxane-A Synthase | 1987 |
Nifedipine in the treatment of Raynaud's phenomenon. Evidence for inhibition of platelet activation.
Topics: Adult; Arachidonic Acid; Arachidonic Acids; beta-Thromboglobulin; Blood Platelets; Double-Blind Method; Female; Humans; Imidazoles; Male; Middle Aged; Nifedipine; Placebos; Platelet Factor 4; Raynaud Disease; Thromboxane-A Synthase | 1985 |
44 other study(ies) available for dazoxiben and arachidonic acid
Article | Year |
---|---|
Electrophysiological responses of the cochlea to transient asphyxia are influenced by arachidonate metabolites.
Topics: Analysis of Variance; Animals; Arachidonic Acid; Cochlear Diseases; Epoprostenol; Female; Guinea Pigs; Imidazoles; Male; Phenylacetates; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Thromboxane A2; Thromboxane-A Synthase; Time Factors | 1992 |
Thromboxane A2 accounts for bronchoconstriction but not for platelet sequestration and microvascular albumin exchanges induced by fMLP in the guinea pig lung.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Blood Platelets; Bronchoconstriction; Guinea Pigs; Imidazoles; Lung; N-Formylmethionine Leucyl-Phenylalanine; Pentanoic Acids; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Pyridines; Radioimmunoassay; Serum Albumin; Suprofen; Thrombocytopenia; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Tretoquinol | 1992 |
Effects of CI-930 on hemostasis, thrombosis, and AA-induced hemodynamic reaction.
Topics: Animals; Arachidonic Acid; Bleeding Time; Cardiotonic Agents; Hemodynamics; Hemostasis; Imidazoles; Male; Mice; Pulmonary Embolism; Pyridazines; Rabbits; Rats; Rats, Inbred Strains; Thrombosis; Thromboxane-A Synthase | 1991 |
[Effect of dazoxiben on the metabolism of arachidonic acid in isolated porcine basilar arteries].
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Basilar Artery; Biological Assay; Imidazoles; In Vitro Techniques; Indomethacin; Leukotrienes; Radioimmunoassay; Swine; Thromboxane B2; Thromboxane-A Synthase | 1990 |
Transient concentrations and agonist potency of PGH2 in platelet activation by endogenous arachidonate.
Topics: Arachidonic Acid; Arachidonic Acids; Blood Platelets; Humans; Imidazoles; In Vitro Techniques; Methylmercury Compounds; Platelet Activation; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Serotonin; Thrombin; Thromboxane A2; Thromboxane-A Synthase | 1989 |
Characterization of N,N'-bis(3-picolyl)-4-methoxy-isophtalamide (picotamide) as a dual thromboxane synthase inhibitor/thromboxane A2 receptor antagonist in human platelets.
Topics: Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cyclic AMP; Fibrinolytic Agents; Humans; Imidazoles; Phthalic Acids; Platelet Aggregation Inhibitors; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Thromboxane-A Synthase; Thromboxanes | 1989 |
Antiaggregatory effects of thromboxane receptor antagonists in vivo.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Triphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Collagen; Fatty Acids, Unsaturated; Fibrinolytic Agents; Hydrazines; Imidazoles; Kinetics; Male; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Rabbits; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Thromboxane-A Synthase; Thromboxanes | 1985 |
Platelet desensitization induced by arachidonic acid is not due to cyclo-oxygenase inactivation and involves the endoperoxide receptor.
Topics: Adenosine Triphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cyclooxygenase Inhibitors; Humans; Imidazoles; Indoles; Microscopy, Electron; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Receptors, Cell Surface; Receptors, Prostaglandin; Receptors, Thromboxane; Salicylates; Thrombin; Thromboxane B2 | 1985 |
Effects of a thromboxane synthetase inhibitor and a cAMP phosphodiesterase inhibitor, singly and in combination, on platelet behaviour.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cyclic AMP; Drug Interactions; Humans; Imidazoles; In Vitro Techniques; Platelet Aggregation; Serotonin; Thromboxane-A Synthase | 1986 |
Modulation by cyclic AMP of arachidonic acid-induced platelet desensitization.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenylyl Cyclases; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Bucladesine; Cyclic AMP; Humans; Imidazoles; In Vitro Techniques; Prostaglandin Endoperoxides, Synthetic; Thromboxane B2 | 1986 |
Inhibition of platelet thromboxane synthetase by 1-(3-benzyloxy-1[E]octenyl)imidazole.
Topics: Adult; Animals; Arachidonic Acid; Arachidonic Acids; Bleeding Time; Blood Platelets; Dinoprostone; Humans; Imidazoles; In Vitro Techniques; Male; Middle Aged; Prostaglandins E; Rabbits; Rats; Rats, Inbred Strains; Thrombosis; Thromboxane B2; Thromboxane-A Synthase | 1986 |
Dazoxiben, UK 38,485 and aspirin: duration of effect for preventing thrombotic sudden death in rabbits.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Imidazoles; Male; Rabbits; Thrombocytopenia; Thrombosis; Thromboxane B2; Time Factors | 1986 |
The effect of thromboxane A2 synthesis inhibitors on platelet aggregation in whole blood.
Topics: Adult; Animals; Arachidonic Acid; Arachidonic Acids; Blood Physiological Phenomena; Collagen; Cyclooxygenase Inhibitors; Humans; Imidazoles; Indomethacin; Male; Mice; Mice, Inbred BALB C; Platelet Aggregation; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Thromboxane A2; Thromboxane-A Synthase | 1987 |
Endothelium-dependent contractions to calcium ionophore A23187, arachidonic acid, and acetylcholine in canine basilar arteries.
Topics: Acetylcholine; Animals; Arachidonic Acid; Arachidonic Acids; Basilar Artery; Calcimycin; Dogs; Endothelium, Vascular; Imidazoles; Indomethacin; Vasoconstriction | 1988 |
Adenylate cyclase activation determines the effect of thromboxane synthase inhibitors on platelet aggregation in vitro. Comparison of platelets from responders and nonresponders.
Topics: Adenylyl Cyclases; Adult; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Dinoprostone; Eicosanoic Acids; Enzyme Activation; Female; Humans; Imidazoles; Indoles; Male; Methacrylates; Middle Aged; Platelet Aggregation; Prostaglandins E; Pyridines; Thromboxane-A Synthase | 1988 |
Exchange of cyclooxygenase dependent metabolites between vessel wall and platelets in arterial thrombosis.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Epoprostenol; Imidazoles; Male; Mesenteric Arteries; Platelet Aggregation; Propionates; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains; Thrombosis; Thromboxane A2; Tranylcypromine | 1988 |
Acetyl glycerylphosphorylcholine aggregates human platelets through two distinct pathways, both dependent on arachidonic acid metabolism.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Catechols; Chromatography, Thin Layer; Cyclooxygenase Inhibitors; Humans; Imidazoles; In Vitro Techniques; Lipoxygenase Inhibitors; Masoprocol; Phospholipases; Platelet Activating Factor; Platelet Aggregation; Prostanoic Acids; Quinacrine; Radioimmunoassay; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxane A2; Thromboxane-A Synthase | 1985 |
Prostaglandins and human platelet aggregation. Implications for the anti-aggregating activity of thromboxane-synthase inhibitors.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Dinoprost; Dinoprostone; Drug Synergism; Humans; Imidazoles; Oxidoreductases; Platelet Aggregation; Prostaglandin D2; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandins; Prostaglandins D; Prostaglandins E; Prostaglandins F; Prostanoic Acids; Thromboxane B2; Thromboxane-A Synthase | 1985 |
Thromboxane synthase inhibition potentiates washed platelet activation by endogenous and exogenous arachidonic acid.
Topics: Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Drug Interactions; Humans; Hydrogen Peroxide; Imidazoles; In Vitro Techniques; Indomethacin; Methylmercury Compounds; Oxidoreductases; Platelet Aggregation; Serotonin; Serum Albumin; Sulfonamides; Thromboxane B2; Thromboxane-A Synthase | 1985 |
Leukotriene F4 and the release of arachidonic acid metabolites from perfused guinea pig lungs in vitro.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Biological Assay; Dinoprostone; Female; Guinea Pigs; Imidazoles; In Vitro Techniques; Indomethacin; Lung; Male; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; SRS-A; Thromboxane B2 | 1985 |
Effects of a thromboxane synthetase inhibitor and a thromboxane antagonist on release and activity of thromboxane A2 and prostacyclin in vitro.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Epoprostenol; Fatty Acids, Unsaturated; Guinea Pigs; Hydrazines; Imidazoles; Male; Muscle Contraction; Muscle, Smooth, Vascular; Oxidoreductases; Rats; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes | 1985 |
Platelet behaviour in normal pregnancy, pregnancy complicated by essential hypertension and pregnancy-induced hypertension.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Epinephrine; Female; Humans; Hypertension; Imidazoles; Platelet Aggregation; Pregnancy; Pregnancy Complications, Cardiovascular; Serotonin | 1985 |
Platelet aggregation in whole blood: the role of thromboxane A2 and adenosine diphosphate.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adenosine Diphosphate; Apyrase; Arachidonic Acid; Arachidonic Acids; Aspirin; Collagen; Cyclooxygenase Inhibitors; Epinephrine; Flurbiprofen; Humans; Imidazoles; In Vitro Techniques; Lipoxygenase Inhibitors; Platelet Aggregation; Pyrazoles; Thrombin; Thromboxane A2; Thromboxane-A Synthase | 1985 |
Thromboxane synthetase inhibitors differentially antagonize thromboxane receptors in vascular smooth muscle.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bicyclic Monoterpenes; Blood Platelets; Cats; Coronary Vessels; Imidazoles; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Oxidoreductases; Pulmonary Artery; Receptors, Cell Surface; Receptors, Prostaglandin; Receptors, Thromboxane; Serotonin; Thromboxane A2; Thromboxane-A Synthase | 1981 |
Effects of thromboxane synthetase inhibition on arachidonate metabolism and platelet behaviour.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Dinoprostone; Epoprostenol; Humans; Imidazoles; In Vitro Techniques; Indomethacin; Oxidoreductases; Platelet Aggregation; Prostaglandins E; Rabbits; Thromboxane B2; Thromboxane-A Synthase | 1983 |
Human blood platelet behaviour after inhibition of thromboxane synthetase.
Topics: Arachidonic Acid; Arachidonic Acids; Blood Platelets; Humans; Imidazoles; In Vitro Techniques; Malondialdehyde; Oxidoreductases; Serotonin; Thromboxane A2; Thromboxane-A Synthase | 1983 |
Effects of dazoxiben and low-dose aspirin on platelet behaviour in man.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Epinephrine; Female; Humans; Imidazoles; Male; Oxidoreductases; Thromboxane-A Synthase | 1983 |
Hyperreactivity of coronary vasculature in platelet-perfused hearts from diabetic rats.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cats; Coronary Circulation; Diabetes Mellitus, Experimental; Heart; Ibuprofen; Imidazoles; Male; Perfusion; Prostaglandins; Rats; Rats, Inbred Strains; Thromboxane-A Synthase | 1983 |
Effect of the thromboxane synthetase inhibitor UK-37,248 (dazoxiben) upon platelet aggregation, coronary artery thrombosis and vascular reactivity.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Coronary Circulation; Coronary Disease; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Hyperemia; Imidazoles; Male; Oxidoreductases; Platelet Aggregation; Thromboxane B2; Thromboxane-A Synthase; Time Factors; Vasodilation | 1983 |
Role of thromboxanes and prostaglandin endoperoxides in the pathogenesis of eicosanoid induced sudden death.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Death, Sudden; Imidazoles; Male; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandins H; Pulmonary Embolism; Rabbits; Thromboxane A2; Thromboxanes; Vasoconstriction | 1983 |
Investigation on a selective non-prostanoic thromboxane antagonist, BM 13.177, in human platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Dose-Response Relationship, Drug; Epinephrine; Humans; Hydrogen Peroxide; Imidazoles; Indomethacin; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandins E; Serotonin; Sulfonamides; Thromboxane A2; Thromboxane B2; Thromboxanes | 1984 |
Pharmacologic inhibition of thromboxane synthetase and platelet aggregation: modulatory role of cyclooxygenase products.
Topics: Adult; Arachidonic Acid; Arachidonic Acids; Chromatography, Gas; Chromatography, Thin Layer; Dinoprost; Dinoprostone; Female; Humans; Imidazoles; Male; Mass Spectrometry; Oxidoreductases; Platelet Aggregation; Prostaglandin D2; Prostaglandins D; Prostaglandins E; Prostaglandins F; Radioimmunoassay; Thromboxane A2; Thromboxane-A Synthase; Thromboxanes | 1984 |
Dazoxiben, a thromboxane synthetase inhibitor, in Raynaud's phenomenon.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Arachidonic Acid; Arachidonic Acids; Double-Blind Method; Drug Evaluation; Female; Forearm; Humans; Imidazoles; Male; Middle Aged; Plethysmography; Radioimmunoassay; Raynaud Disease; Thromboxane B2 | 1984 |
Serum albumin enhances the impairment of platelet aggregation with thromboxane synthase inhibition by increasing the formation of prostaglandin D2.
Topics: Adenine; Adult; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Female; Humans; Imidazoles; Male; Middle Aged; Oxidoreductases; Platelet Aggregation; Prostaglandin D2; Prostaglandins D; Serum Albumin; Thromboxane-A Synthase | 1984 |
Comparison of the effects of selective inhibition of thromboxane synthase with those of inhibition of the cyclooxygenase enzyme in man.
Topics: 6-Ketoprostaglandin F1 alpha; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Imidazoles; Male; Oxidoreductases; Pyridines; Thromboxane-A Synthase; Time Factors | 1984 |
Comparison of radioimmunoassay and high-resolution gas chromatography mass spectrometry for the quantitative determination of serum thromboxane B2 and 6-keto-PGF1 alpha after pharmacological blockade of thromboxane synthetase.
Topics: 6-Ketoprostaglandin F1 alpha; Arachidonic Acid; Arachidonic Acids; Gas Chromatography-Mass Spectrometry; Humans; Imidazoles; In Vitro Techniques; Oxidoreductases; Radioimmunoassay; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes | 1984 |
Inhibition of arachidonate-induced human platelet aggregation by a single low oral dose of aspirin in combination with a thromboxane synthase inhibitor.
Topics: Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Female; Humans; Imidazoles; Male; Oxidoreductases; Platelet Aggregation; Thromboxane-A Synthase | 1984 |
Beneficial effects of a new thromboxane synthetase inhibitor in arachidonate-induced sudden death.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Death, Sudden; Electrocardiography; Heart Rate; Imidazoles; Male; Oxidoreductases; Prostaglandins F; Pulmonary Artery; Rabbits; Serotonin; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Vasoconstrictor Agents | 1981 |
Arachidonic acid induces human platelet-fibrin retraction: the role of platelet cyclic endoperoxides.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alprostadil; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Clot Retraction; Epoprostenol; Fatty Acids, Unsaturated; Fibrin; Humans; Imidazoles; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandins D; Prostaglandins E; Prostaglandins H; Prostaglandins, Synthetic; Thromboxane B2 | 1982 |
Platelet activation induced by interleukin-6: evidence for a mechanism involving arachidonic acid metabolism.
Topics: Adenosine Diphosphate; Arachidonic Acid; beta-Thromboglobulin; Blood Platelets; Calcimycin; Cytoskeleton; Drug Synergism; Humans; Imidazoles; Indomethacin; Interleukin-6; Platelet Activation; Prostaglandin-Endoperoxide Synthases; Recombinant Proteins; Thromboxane B2 | 1994 |
Tissue eicosanoids and vascular permeability in rats with chronic biliary obstruction.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Bile Ducts; Capillary Permeability; Cholestasis; Eicosanoids; Imidazoles; Kidney; Ligation; Liver Cirrhosis, Biliary; Lung; Male; Rats; Rats, Sprague-Dawley; Serum Albumin, Radio-Iodinated; Thromboxane A2; Thromboxane B2 | 1993 |
Redirection of eicosanoid metabolism in mPGES-1-deficient macrophages.
Topics: Animals; Arachidonic Acid; Blotting, Western; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Eicosanoids; Fatty Acids, Unsaturated; Genotype; Imidazoles; Inflammation; Intramolecular Oxidoreductases; Kinetics; Lipopolysaccharides; Macrophages; Mice; Mice, Transgenic; Microsomes; Prostaglandin-E Synthases; Prostaglandins; Thioglycolates; Thromboxane B2; Time Factors | 2005 |
Effect of inhibitors of arachidonic acid conversion in platelets on thrombin-fibrinogen interaction and thrombin tolerance.
Topics: Animals; Arachidonic Acid; Aspirin; Blood Platelets; Dose-Response Relationship, Drug; Fibrinogen; Imidazoles; Male; Platelet Aggregation; Quinacrine; Rats; Thrombin | 2007 |
Role of superoxide and thromboxane receptors in acute angiotensin II-induced vasoconstriction of rabbit vessels.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Arachidonic Acid; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Imidazoles; Indomethacin; Isoprostanes; Male; Mesenteric Arteries; Models, Animal; Muscle, Smooth, Vascular; Rabbits; Receptors, Thromboxane; Superoxides; Vasoconstriction; Vasoconstrictor Agents | 2011 |