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dazoxiben and 6-ketoprostaglandin f1 alpha

dazoxiben has been researched along with 6-ketoprostaglandin f1 alpha in 51 studies

Research

Studies (51)

TimeframeStudies, this research(%)All Research%
pre-199040 (78.43)18.7374
1990's8 (15.69)18.2507
2000's3 (5.88)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arreto, CD; Bureau, MF; De Clerck, F; Lefort, J; Vargaftig, BB1
Asai, F; Ito, T; Matsuda, K; Oshima, T; Ushiyama, S1
Asai, F; Ito, T; Kobayashi, S; Oshima, T1
Lin, AY; Rui, YC; Sun, DX1
Archibald, JL; Bradley, G; Ennis, C; Opalko, A; Shepperson, NB; Ward, TJ; White, JC1
Long, K; Rui, YC; Sun, DX1
Arnout, J; Bounameaux, H; Deckmyn, H; Gresele, P; Perez-Requejo, JL; Vermylen, J1
Enderson, B; Price, S; Rice, CL; Winn, R1
Ghai, R; Lindsay, LA; Olson, RW; Sakane, Y; Smith, EF1
Cohen, DS; Kimble, EF; Ku, EC; Olson, RW; Renfroe, HB; Smith, EF1
Mallarkey, G; Smith, GM1
Ernst, A; Lotz, P; Mest, HJ; Taube, C1
Fenton, JW; Horgan, MJ; Malik, AB1
Flynn, JT; Gee, MH; Perkowski, SZ; Tahamont, MV; Wasserman, MA1
Glenn, TM; Oei, HH; Robson, RD; Sakane, Y; Zoganas, HC1
Gerdin, B; Saldeen, T; Sandler, H1
Arnout, J; Deckmyn, H; Gresele, P; Vermylen, J; Zoja, C1
Bergqvist, D; Björck, CG; Dougan, P; Esquivel, CO; Lannerstad, O; Nilsson, B; Saldeen, P; Saldeen, T1
Joseph, R; Littlewood, J; Poole, CJ; Rose, FC; Steiner, JT1
Hillyard, CJ; Martin, TJ; Nolan, RD; Partridge, NC1
Davies, JA; Martin, MF; Menys, VC; Tindall, H; Tooke, JE1
Charleson, S; Letts, LG; Lord, A1
Greenberg, R; Liu, EC; O'Keefe, EH; Ogletree, ML1
Carreras, LO; Defreyn, G; Machin, SJ; Van Schaeren, J; Vermylen, J; Verstraete, M1
Cerletti, C; Chiabrando, C; de Gaetano, G; Fanelli, R1
Fletcher, MS; Kakkar, VV; Westwick, J2
Cook, JA; Halushka, PV; Wise, WC1
Dodd, NJ; Gordge, MP; Weston, MJ1
Davies, JA; Menys, VC2
Barfort, P; Jørgensen, KA; Kemp, E; Knudsen, JB; Larsen, S; Petersen, PH; Starklint, H1
Bevan, JA; Carter, AJ; Hanley, SP; Morgan, WE; Turner, DR1
Garcia, G; Luderer, JR; Neumyer, MM; Nicholas, GG; Riley, DL; Schneck, DW; Vary, JE1
Brash, A; Fitzgerald, G; Oates, JA1
Castagnoli, MN; Cerletti, C; Chiabrando, C; de Gaetano, G; Fanelli, R; Noseda, A; Rajtar, G1
Deckmyn, H; Spitz, B; Van Assche, FA; Vermylen, J1
FitzGerald, GA; Pedersen, AK; Watson, ML1
Buja, LM; Bush, LR; Campbell, WB; Tilton, GD; Willerson, JT1
Daskalopoulos, G; Kronborg, I; Rector, W; Reynolds, T; Zipser, RD1
Randall, MJ; Wilding, RI2
Muccitelli, RM; Osborn, RR; Weichman, BM1
Dale, J; Myhre, E; Parry, J; Thaulow, E1
Maguire, ED; Wallis, RB1
Amore, C; Buczko, W; D'Adamo, MC; De Curtis, A; De Gaetano, G; Donati, MB; Iacoviello, L1
Yuan, W1
Chang, SW; Ohara, N; Voelkel, NF1
De La Cruz, JP; Moreno, A; Ruiz-Ruiz, MI; Sánchez De La Cuesta, F1
Bedouch, P; Bessard, G; Chavanon, O; Cracowski, JL; Devillier, P; Stanke-Labesque, F1
Arrebola, MM; De La Cruz, JP; Escalante, R; Guerrero, A; Sánchez de La Cuesta, F; Villalobos, MA1

Trials

5 trial(s) available for dazoxiben and 6-ketoprostaglandin f1 alpha

ArticleYear
Thromboxane A2 and prostacyclin do not modulate the systemic hemodynamic response to cold in humans.
    The Journal of laboratory and clinical medicine, 1985, Volume: 106, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; beta-Thromboglobulin; Blood Pressure; Cold Temperature; Double-Blind Method; Epoprostenol; Fingers; Humans; Imidazoles; Indomethacin; Male; Platelet Aggregation; Regional Blood Flow; Sulfonamides; Thromboxane A2; Thromboxane B2; Vascular Resistance; Vasoconstriction

1985
Effect of dazoxiben, a thromboxane synthetase inhibitor on skin-blood flow following cold challenge in patients with Raynaud's phenomenon.
    European journal of clinical investigation, 1985, Volume: 15, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Cold Temperature; Drug Evaluation; Female; Fibrinopeptide A; Fingers; Humans; Imidazoles; Male; Random Allocation; Raynaud Disease; Regional Blood Flow; Skin; Thromboxane A2; Thromboxane-A Synthase

1985
Thromboxane synthetase inhibition as antithrombotic strategy.
    Lancet (London, England), 1981, May-16, Volume: 1, Issue:8229

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Blood Platelets; Clinical Trials as Topic; Double-Blind Method; Fibrinolytic Agents; Humans; Imidazoles; Male; Oxidoreductases; Platelet Aggregation; Prostaglandins E; Prostaglandins F; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase

1981
Use of a thromboxane synthetase inhibitor, dazoxiben, during haemodialysis.
    British journal of clinical pharmacology, 1983, Volume: 15 Suppl 1

    Topics: 6-Ketoprostaglandin F1 alpha; Blood Coagulation; Clinical Trials as Topic; Double-Blind Method; Humans; Imidazoles; Oxidoreductases; Platelet Count; Renal Dialysis; Thromboxane B2; Thromboxane-A Synthase

1983
The effect of a thromboxane synthetase inhibitor, dazoxiben, and acetylsalicylic acid on platelet function and prostaglandin metabolism.
    Thrombosis and haemostasis, 1983, Oct-31, Volume: 50, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Aspirin; Blood Platelets; Humans; Imidazoles; Male; Middle Aged; Oxidoreductases; Platelet Adhesiveness; Platelet Aggregation; Prostaglandins; Thromboxane B2; Thromboxane-A Synthase

1983

Other Studies

46 other study(ies) available for dazoxiben and 6-ketoprostaglandin f1 alpha

ArticleYear
Thromboxane A2 accounts for bronchoconstriction but not for platelet sequestration and microvascular albumin exchanges induced by fMLP in the guinea pig lung.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Blood Platelets; Bronchoconstriction; Guinea Pigs; Imidazoles; Lung; N-Formylmethionine Leucyl-Phenylalanine; Pentanoic Acids; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Pyridines; Radioimmunoassay; Serum Albumin; Suprofen; Thrombocytopenia; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Tretoquinol

1992
In vitro antiplatelet profiles of the new thromboxane synthetase inhibitor sodium 2-(1-imidazolylmethyl)-4,5-dihydrobenzo[b]thiophene-6-carboxylate.
    Arzneimittel-Forschung, 1991, Volume: 41, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Animals; Aspirin; Dogs; Humans; Imidazoles; In Vitro Techniques; Male; Methacrylates; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Thiophenes; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1991
Role of activated platelets in endotoxin-induced DIC in rats.
    Thrombosis research, 1990, Aug-15, Volume: 59, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Coagulation; Disseminated Intravascular Coagulation; Endotoxins; Epoprostenol; Fibrin; Humans; Imidazoles; Kidney Glomerulus; Male; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Count; Prostaglandins, Synthetic; Rats; Rats, Inbred Strains; Sulfonamides; Thromboxane B2; Thromboxane-A Synthase; Ticlopidine

1990
[Effect of dazoxiben on the metabolism of arachidonic acid in isolated porcine basilar arteries].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1990, Volume: 11, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Basilar Artery; Biological Assay; Imidazoles; In Vitro Techniques; Indomethacin; Leukotrienes; Radioimmunoassay; Swine; Thromboxane B2; Thromboxane-A Synthase

1990
Design of an antithrombotic-antihypertensive agent (Wy 27569). Synthesis and evaluation of a series of 2-heteroaryl-substituted dihydropyridines.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Antihypertensive Agents; Chemical Phenomena; Chemistry; Dihydropyridines; Drug Design; Fibrinolytic Agents; Humans; Hypertension; Imidazoles; Nitrendipine; Rats; Rats, Inbred SHR; Structure-Activity Relationship; Thromboxane B2; Thromboxane-A Synthase

1990
[Effect of dazoxiben on cerebrovascular resistance in rabbits].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1989, Volume: 10, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cerebrovascular Circulation; Imidazoles; Male; Rabbits; Thromboxane B2; Thromboxane-A Synthase; Vascular Resistance

1989
Indomethacin, but not dazoxiben, reduced lung fluid filtration after E. coli infusion.
    Journal of applied physiology (Bethesda, Md. : 1985), 1988, Volume: 64, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Body Water; Cardiac Output; Escherichia coli Infections; Imidazoles; Indomethacin; Lung; Lymph; Pulmonary Circulation; Reference Values; Thromboxane B2; Thromboxane-A Synthase

1988
Dazoxiben, UK 38,485 and aspirin: duration of effect for preventing thrombotic sudden death in rabbits.
    Thrombosis research, 1986, Jul-15, Volume: 43, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Imidazoles; Male; Rabbits; Thrombocytopenia; Thrombosis; Thromboxane B2; Time Factors

1986
CGS 15435A, a thromboxane synthetase inhibitor with an extended duration of action: a comparison with dazoxiben.
    European journal of pharmacology, 1987, Jan-20, Volume: 133, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme System; Death, Sudden; Dinoprostone; Dogs; Epoprostenol; Imidazoles; In Vitro Techniques; Indoles; Intramolecular Oxidoreductases; Lipoxygenase Inhibitors; Platelet Count; Prostaglandins E; Rabbits; Thromboxane B2; Thromboxane-A Synthase

1987
A comparative study of the involvement of the prostaglandin H2/thromboxane A2 pathway in intravascular platelet aggregation in guinea-pigs and rats.
    British journal of pharmacology, 1985, Volume: 84, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Collagen; Female; Guinea Pigs; Imidazoles; In Vitro Techniques; Indomethacin; Male; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Prostaglandins, Synthetic; Rats; Rats, Inbred Strains; Receptors, Prostaglandin; Receptors, Thromboxane; Species Specificity; Thromboxane A2; Thromboxane B2; Thromboxanes

1985
Dazoxiben-induced changes in the thromboxane/prostacyclin balance in the lateral cochlear wall of the guinea pig.
    Archives of oto-rhino-laryngology, 1988, Volume: 245, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cochlea; Epoprostenol; Female; Guinea Pigs; Imidazoles; Male; Thromboxane-A Synthase; Thromboxanes

1988
Alpha-thrombin-induced pulmonary vasoconstriction.
    Journal of applied physiology (Bethesda, Md. : 1985), 1987, Volume: 63, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Female; Guinea Pigs; Hirudins; Imidazoles; Indomethacin; Lung; Male; Organ Size; Pulmonary Artery; Pulmonary Wedge Pressure; Thrombin; Thromboxane B2; Thromboxane-A Synthase; Vasoconstriction

1987
Thromboxane as a mediator of pulmonary dysfunction during intravascular complement activation in sheep.
    The American review of respiratory disease, 1986, Volume: 133, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Capillary Permeability; Complement Activation; Hypertension, Pulmonary; Hypoxia; Imidazoles; Leukocytes; Lung Diseases; Plasma; Pulmonary Circulation; Sheep; Sulfonamides; Thromboxane A2; Zymosan

1986
Inhibition of thromboxane biosynthesis in splanchnic ischemia shock.
    Circulatory shock, 1986, Volume: 18, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Cardiac Output; Dogs; Female; Glucuronidase; Heart Rate; Imidazoles; Indomethacin; Ischemia; Kinetics; Male; Shock; Splanchnic Circulation; Thromboxane B2; Thromboxane-A Synthase; Vascular Resistance

1986
Studies on the role of thromboxane in thrombin-induced pulmonary insufficiency in the rat.
    Thrombosis research, 1986, Apr-15, Volume: 42, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Cattle; Fibrinogen; Fibrinolysis; Imidazoles; Indomethacin; Lung; Lung Diseases; Male; Organ Size; Platelet Count; Rats; Rats, Inbred Strains; Serum Albumin; Thrombin; Thromboxane B2; Thromboxane-A Synthase

1986
Lack of synergism between dazoxiben and dipyridamole following administration to man.
    Thrombosis research, 1985, Jan-01, Volume: 37, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Dipyridamole; Drug Synergism; Humans; Imidazoles; Male; Oxidoreductases; Platelet Aggregation; Thromboxane-A Synthase

1985
The effect of inhibition of thromboxane synthesis in experimental thrombosis and hemostasis.
    Thrombosis research, 1985, Feb-01, Volume: 37, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Platelets; Carotid Arteries; Female; Hemostasis; Humans; Imidazoles; Jugular Veins; Male; Oxidoreductases; Rabbits; Sheep; Thrombosis; Thromboxane B2; Thromboxane-A Synthase; Umbilical Veins

1985
Thromboxane synthetase inhibition: potential therapy in migraine.
    Headache, 1985, Volume: 25, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Adolescent; Adult; Aged; Female; Humans; Imidazoles; Male; Middle Aged; Migraine Disorders; Oxidoreductases; Thromboxane-A Synthase

1985
Regulation of prostaglandin production by osteoblast-rich calvarial cells.
    Prostaglandins, 1985, Volume: 30, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Animals, Newborn; Bradykinin; Cells, Cultured; Dexamethasone; Dinoprostone; Epidermal Growth Factor; Imidazoles; Indomethacin; Osteoblasts; Prostaglandins; Prostaglandins E; Pyrazoles; Pyrazolones; Rats; Thrombin

1985
Leukotriene F4 and the release of arachidonic acid metabolites from perfused guinea pig lungs in vitro.
    Prostaglandins, 1985, Volume: 29, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Biological Assay; Dinoprostone; Female; Guinea Pigs; Imidazoles; In Vitro Techniques; Indomethacin; Lung; Male; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; SRS-A; Thromboxane B2

1985
Effects of a thromboxane synthetase inhibitor and a thromboxane antagonist on release and activity of thromboxane A2 and prostacyclin in vitro.
    Prostaglandins, 1985, Volume: 29, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Epoprostenol; Fatty Acids, Unsaturated; Guinea Pigs; Hydrazines; Imidazoles; Male; Muscle Contraction; Muscle, Smooth, Vascular; Oxidoreductases; Rats; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1985
Is immunoreactive 6-keto-PGF1 alpha measured in serum after treatment with thromboxane-synthetase inhibitors an index of prostacyclin synthesis?
    Lancet (London, England), 1984, Apr-28, Volume: 1, Issue:8383

    Topics: 6-Ketoprostaglandin F1 alpha; Epoprostenol; Humans; Imidazoles; Oxidoreductases; Radioimmunoassay; Thromboxane-A Synthase

1984
Inhibition of thromboxane formation prevents endotoxin-induced renal fibrin deposition in jaundiced rats.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1983, Volume: 12

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Endotoxins; Epoprostenol; Fibrin; Imidazoles; Indomethacin; Jaundice; Kidney; Male; Rats; Rats, Inbred Strains; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1983
Beneficial effects of UK 37248, a thromboxane synthetase inhibitor, in experimental endotoxic shock in the rat.
    British journal of clinical pharmacology, 1983, Volume: 15 Suppl 1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Glucose; Endotoxins; Imidazoles; Macrophages; Male; Oxidoreductases; Platelet Count; Prostaglandins E; Radioimmunoassay; Rats; Salmonella enteritidis; Shock, Septic; Splanchnic Circulation; Thromboxane-A Synthase

1983
Selective inhibition of thromboxane synthetase with dazoxiben - basis of its inhibitory effect on platelet adhesion.
    Thrombosis and haemostasis, 1983, Apr-28, Volume: 49, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta; Epoprostenol; Imidazoles; Male; Oxidoreductases; Platelet Adhesiveness; Rabbits; Thrombin; Thromboxane B2; Thromboxane-A Synthase

1983
The survival of pig to rabbit renal xenografts during inhibition of thromboxane synthesis.
    Thrombosis research, 1983, Dec-15, Volume: 32, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Platelets; Drug Evaluation, Preclinical; Graft Survival; Imidazoles; Kidney Transplantation; Rabbits; Swine; Thromboxane B2; Thromboxane-A Synthase; Transplantation, Heterologous

1983
A comparison of human pulmonary arterial and venous prostacyclin and thromboxane synthesis--effect of a thromboxane synthase inhibitor.
    Thrombosis and haemostasis, 1984, Apr-30, Volume: 51, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Endothelium; Epoprostenol; Humans; Imidazoles; Oxidoreductases; Pulmonary Artery; Pulmonary Veins; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1984
Dazoxiben, a thromboxane synthetase inhibitor, in Raynaud's phenomenon.
    Clinical pharmacology and therapeutics, 1984, Volume: 36, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Arachidonic Acid; Arachidonic Acids; Double-Blind Method; Drug Evaluation; Female; Forearm; Humans; Imidazoles; Male; Middle Aged; Plethysmography; Radioimmunoassay; Raynaud Disease; Thromboxane B2

1984
Comparison of the effects of selective inhibition of thromboxane synthase with those of inhibition of the cyclooxygenase enzyme in man.
    Transactions of the American Clinical and Climatological Association, 1984, Volume: 95

    Topics: 6-Ketoprostaglandin F1 alpha; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Imidazoles; Male; Oxidoreductases; Pyridines; Thromboxane-A Synthase; Time Factors

1984
Comparison of radioimmunoassay and high-resolution gas chromatography mass spectrometry for the quantitative determination of serum thromboxane B2 and 6-keto-PGF1 alpha after pharmacological blockade of thromboxane synthetase.
    Prostaglandins, leukotrienes, and medicine, 1984, Volume: 16, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Arachidonic Acid; Arachidonic Acids; Gas Chromatography-Mass Spectrometry; Humans; Imidazoles; In Vitro Techniques; Oxidoreductases; Radioimmunoassay; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1984
Prostacyclin in pregnancy.
    European journal of obstetrics, gynecology, and reproductive biology, 1984, Volume: 18, Issue:5-6

    Topics: 6-Ketoprostaglandin F1 alpha; Adaptation, Physiological; Animals; Blood Coagulation Factors; Epoprostenol; Female; Fetal Death; Hemodynamics; Humans; Hypertension; Imidazoles; Lupus Coagulation Inhibitor; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Rats; Thrombosis; Thromboxane-A Synthase; Vitamin E Deficiency

1984
Thromboxane-mediated activation of platelets and enhancement of platelet uptake onto collagen-coated glass or deendothelialized rabbit aorta. Comparative effects of a thromboxane antagonist (EPO45) and a thromboxane synthetase inhibitor (dazoxiben).
    Laboratory investigation; a journal of technical methods and pathology, 1984, Volume: 50, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Collagen; Imidazoles; In Vitro Techniques; Indomethacin; Male; Muscle, Smooth, Vascular; Platelet Adhesiveness; Platelet Aggregation; Prostaglandins, Synthetic; Rabbits; Serotonin; Thromboxane B2

1984
Inhibition of thromboxane biosynthesis in serum: limitations of the measurement of immunoreactive 6-keto-PGF1 alpha.
    Thrombosis research, 1984, Jan-01, Volume: 33, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Chemical Phenomena; Chemistry, Physical; Gas Chromatography-Mass Spectrometry; Humans; Imidazoles; Immunoassay; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1984
Effects of the selective thromboxane synthetase inhibitor dazoxiben on variations in cyclic blood flow in stenosed canine coronary arteries.
    Circulation, 1984, Volume: 69, Issue:6

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 6-Ketoprostaglandin F1 alpha; Animals; Coronary Circulation; Coronary Disease; Coronary Vessels; Dogs; Female; Hemodynamics; Imidazoles; Male; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Thromboxane B2

1984
Therapeutic trial of thromboxane synthesis inhibition in the hepatorenal syndrome.
    Gastroenterology, 1984, Volume: 87, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Acute Kidney Injury; Adult; Creatinine; Dinoprostone; Drug Evaluation; Hepatitis, Alcoholic; Humans; Imidazoles; Middle Aged; Oxidoreductases; Prostaglandins E; Syndrome; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1984
Acute arterial thrombosis in rabbits: reduced platelet accumulation after treatment with dazoxiben hydrochloride (UK 37,248-01).
    British journal of clinical pharmacology, 1983, Volume: 15 Suppl 1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Blood Platelets; Electric Stimulation; Imidazoles; Indium; Male; Oxidoreductases; Rabbits; Radioisotopes; Thrombosis; Thromboxane B2; Thromboxane-A Synthase

1983
Effect of inhibition of thromboxane production on the leukotriene D4-mediated bronchoconstriction in the guinea pig.
    Prostaglandins, 1983, Volume: 26, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Bronchi; Chromones; Guinea Pigs; Imidazoles; Meclofenamic Acid; SRS-A; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1983
In vivo redirection of prostaglandin endoperoxides into 6-keto PGF1 alpha formation by thromboxane synthetase inhibitors in the rat.
    Thrombosis research, 1983, Oct-01, Volume: 32, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Platelets; Collagen; Imidazoles; Indoles; Indomethacin; Male; Oxidoreductases; Pyridines; Radioimmunoassay; Rats; Rats, Inbred Strains; Thrombocytopenia; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1983
Endotoxin, prostaglandins and renal fibrin deposition in obstructive jaundice.
    The British journal of surgery, 1982, Volume: 69, Issue:10

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cholestasis; Endotoxins; Epoprostenol; Escherichia coli; Fibrin; Imidazoles; Indomethacin; Kidney; Male; Prostaglandins; Rats; Rats, Inbred Strains; Thromboxane B2

1982
Acute arterial thrombosis in rabbits: reduced platelet accumulation after treatment with thromboxane synthetase inhibitor dazoxiben hydrochloride, (UK-37, 248-01).
    Thrombosis research, 1982, Dec-01, Volume: 28, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Acute Disease; Animals; Aspirin; Carotid Artery Thrombosis; Cells, Cultured; Enzyme Inhibitors; Fibrinolytic Agents; Imidazoles; In Vitro Techniques; Oxidoreductases; Platelet Aggregation; Rabbits; Thromboxane B2; Thromboxane-A Synthase

1982
Prostacyclin is required for t-PA release after venous occlusion.
    The American journal of physiology, 1994, Volume: 266, Issue:2 Pt 2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Blood Pressure; Dose-Response Relationship, Drug; Fibrinolysis; Iloprost; Imidazoles; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains; Thromboxane-A Synthase; Tissue Plasminogen Activator; Vena Cava, Inferior

1994
[Changes in renal cortical thromboxane A2, prostaglandin F1 alpha and effects of dazoxiben, chuan xiong on in situ immune complex glomerulonephritis in rats].
    Zhonghua yi xue za zhi, 1993, Volume: 73, Issue:9

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Antigen-Antibody Complex; Drugs, Chinese Herbal; Glomerulonephritis; Imidazoles; Kidney Cortex; Male; Rats; Rats, Sprague-Dawley; Serum Albumin, Bovine; Thromboxane B2; Thromboxane-A Synthase

1993
Tissue eicosanoids and vascular permeability in rats with chronic biliary obstruction.
    Hepatology (Baltimore, Md.), 1993, Volume: 18, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Bile Ducts; Capillary Permeability; Cholestasis; Eicosanoids; Imidazoles; Kidney; Ligation; Liver Cirrhosis, Biliary; Lung; Male; Rats; Rats, Sprague-Dawley; Serum Albumin, Radio-Iodinated; Thromboxane A2; Thromboxane B2

1993
Effect of DT-TX 30, a combined thromboxane synthase inhibitor and thromboxane receptor antagonist, on retinal vascularity in experimental diabetes mellitus.
    Thrombosis research, 2000, Feb-01, Volume: 97, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Glucose; Chlorobenzenes; Collagen; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Enzyme Inhibitors; Imidazoles; Male; Platelet Aggregation; Pyridines; Rats; Rats, Wistar; Receptors, Thromboxane; Retinal Vessels; Thromboxane B2; Thromboxane-A Synthase

2000
Angiotensin II-induced contractions in human internal mammary artery: effects of cyclooxygenase and lipoxygenase inhibition.
    Cardiovascular research, 2000, Volume: 47, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Angiotensin II; Benzoquinones; Biphenyl Compounds; Cyclooxygenase Inhibitors; Depression, Chemical; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavanones; Flavonoids; Heptanoic Acids; Humans; Imidazoles; In Vitro Techniques; Indomethacin; Leukotrienes; Lipoxygenase Inhibitors; Mammary Arteries; Propionates; Pyrazoles; Quinolines; Receptors, Thromboxane; Substance P; Thromboxane B2; Thromboxane-A Synthase; Vasoconstriction

2000
Effects of the selective inhibition of platelet thromboxane synthesis on the platelet-subendothelium interaction.
    British journal of pharmacology, 2002, Volume: 137, Issue:7

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Animals; Aspirin; Blood Platelets; Chlorobenzenes; Cyclooxygenase Inhibitors; Dinoprost; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Imidazoles; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyridines; Rabbits; Receptors, Thromboxane; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

2002