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dazmegrel and 6-ketoprostaglandin f1 alpha

dazmegrel has been researched along with 6-ketoprostaglandin f1 alpha in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199024 (82.76)18.7374
1990's4 (13.79)18.2507
2000's1 (3.45)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bloch, KJ; Hoaglin, DC; Morel, DR; Robinson, DR; Skoskiewicz, M; Zapol, WM1
Aramburo, MJ; Hammerman, C; Hill, V1
Himmelstein, SI; Klotman, PE1
Demling, RH; LaLonde, C1
Chen, P; Raj, JU1
Apprill, P; Ashton, J; Buja, LM; Campbell, WB; Raheja, S; Schmitz, JM; Tilton, G; Willerson, JT1
Hammerman, C; Komar, K; Meadow, W; Strates, E1
Hardee, GE; Hardee, MM; Moore, JN2
Ghai, R; Lindsay, LA; Olson, RW; Sakane, Y; Smith, EF1
Brigham, KL; Ogletree, ML; Snapper, JR1
Clement, RE; Fiallo, V; Fink, MP; Gardiner, WM; Morrissey, PE; Stein, KL1
Angus, JA; Crabb, DJ; Knight, KR; Martin, TJ; Niall, M; O'Brien, BM1
Moore, JN; Semrad, SD1
Peskar, BA; Scheid, P; Shams, H1
Helmchen, U; Kudelka, S; Stahl, RA1
Cattell, V; Cook, HT; Moncada, S; Salmon, JA; Smith, J1
Bjøro, K; Hovig, T; Stokke, KT; Stray-Pedersen, S1
Brigham, KL; Butka, BJ; Newman, JH1
Beck, S; Brown, CB; Fox, M; Gibbons, CP; Lindsey, NJ; Preston, FE; Raftery, AT; Slater, DN; Wiley, KN1
Anner, H; Hechtman, HB; Kaufman, RP; Kobzik, L; Shepro, D; Valeri, CR1
Carpenter, LJ; Roth, RA1
Bennett, A; Carroll, MA; Corrigan, CJ; Melhuish, PB; Patel, S; Stamford, IF1
Zipser, RD1
Bernutz, C; Böhlig, B; Fischer, S; Struppler, M; Weber, PC; Wober, W1
Li, JX; Lu, CY; Oliver, JR; Philips, JB1
Grantham, KD; Gray, BM; Li, JX; Oliver, JR; Philips, JB; Pritchard, DG1
Ahmed, Y; Elder, MG; Sullivan, MH1
Arikawa, E; Galipeau, D; McNeill, JH; Sekirov, I1

Trials

2 trial(s) available for dazmegrel and 6-ketoprostaglandin f1 alpha

ArticleYear
Effects of selective inhibition of thromboxane synthesis on renal function in humans.
    The American journal of physiology, 1985, Volume: 248, Issue:6 Pt 2

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Double-Blind Method; Glomerular Filtration Rate; Humans; Imidazoles; Inulin; Kidney; Male; Oxidoreductases; p-Aminohippuric Acid; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1985
The influence of selective thromboxane synthetase inhibition with a novel imidazole derivative, UK-38,485, on prostanoid formation in man.
    Circulation, 1983, Volume: 68, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Adolescent; Adult; Blood Platelets; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Imidazoles; Male; Middle Aged; Oxidoreductases; Random Allocation; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1983

Other Studies

27 other study(ies) available for dazmegrel and 6-ketoprostaglandin f1 alpha

ArticleYear
Leukotrienes, thromboxane A2, and prostaglandins during systemic anaphylaxis in sheep.
    The American journal of physiology, 1991, Volume: 261, Issue:3 Pt 2

    Topics: 6-Ketoprostaglandin F1 alpha; Anaphylaxis; Animals; Blood Pressure; Chromones; Cyclooxygenase Inhibitors; Dinitrophenols; Female; Histamine Release; Imidazoles; Leukotriene E4; Leukotrienes; Lung; Lymph; Male; Meclofenamic Acid; Prostaglandins; Pulmonary Circulation; Serum Albumin, Bovine; Sheep; SRS-A; Stroke Volume; Thromboxane B2; Thromboxane-A Synthase; Time Factors; Vascular Resistance

1991
Lipoxygenase and cyclooxygenase blockade by BW755C does not prevent the secondary phase of septic pulmonary hypertension.
    Prostaglandins, leukotrienes, and essential fatty acids, 1989, Volume: 37, Issue:2

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Cyclooxygenase Inhibitors; Heart Rate; Hemodynamics; Hypertension, Pulmonary; Imidazoles; Lipoxygenase Inhibitors; Pyrazoles; Swine; Thromboxane B2; Thromboxane-A Synthase; Time Factors

1989
The role of thromboxane in two-kidney, one-clip Goldblatt hypertension in rats.
    The American journal of physiology, 1989, Volume: 257, Issue:2 Pt 2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Biphenyl Compounds; Blood Pressure; Glomerular Filtration Rate; Heptanoic Acids; Hypertension, Renovascular; Imidazoles; Kidney; Male; Rats; Rats, Inbred Strains; Receptors, Prostaglandin; Receptors, Thromboxane; Reference Values; Regional Blood Flow; Renal Circulation; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1989
Inhibition of thromboxane synthetase accentuates hemodynamic instability and burn edema in the anesthetized sheep model.
    Surgery, 1989, Volume: 105, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Flow Velocity; Blood Volume; Burns; Cardiac Output; Disease Models, Animal; Edema; Hemodynamics; Imidazoles; Lymph; Oxygen Consumption; Sheep; Skin Diseases; Thromboxane-A Synthase; Vascular Resistance; Vasodilation

1989
Role of eicosanoids in hypoxic vasoconstriction in isolated lamb lungs.
    The American journal of physiology, 1987, Volume: 253, Issue:3 Pt 2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Chromones; Epoprostenol; Hypoxia; Imidazoles; In Vitro Techniques; Indomethacin; Lipoxygenase; Lung; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pulmonary Circulation; Receptors, Leukotriene; Receptors, Prostaglandin; Sheep; SRS-A; Thromboxane B2; Thromboxanes; Vasoconstriction

1987
Cyclic blood flow variations induced by platelet-activating factor in stenosed canine coronary arteries despite inhibition of thromboxane synthetase, serotonin receptors, and alpha-adrenergic receptors.
    Circulation, 1985, Volume: 72, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Adrenergic alpha-Antagonists; Animals; Arteriosclerosis; Coronary Circulation; Coronary Disease; Dogs; Hemodynamics; Imidazoles; Male; Platelet Activating Factor; Platelet Aggregation; Serotonin Antagonists; Thromboxane B2

1985
Selective inhibition of thromboxane synthetase reduces group-B-beta-hemolytic-streptococci-induced pulmonary hypertension in piglets.
    Developmental pharmacology and therapeutics, 1988, Volume: 11, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Animals, Newborn; Epoprostenol; Hypertension, Pulmonary; Imidazoles; Radioimmunoassay; Streptococcal Infections; Swine; Thromboxane B2; Thromboxane-A Synthase

1988
Modulation of arachidonic acid metabolism in endotoxic horses: comparison of flunixin meglumine, phenylbutazone, and a selective thromboxane synthetase inhibitor.
    American journal of veterinary research, 1986, Volume: 47, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Clonixin; Endotoxins; Escherichia coli; Horses; Imidazoles; Lactates; Male; Nicotinic Acids; Phenylbutazone; Thromboxane B2; Thromboxane-A Synthase

1986
Dazoxiben, UK 38,485 and aspirin: duration of effect for preventing thrombotic sudden death in rabbits.
    Thrombosis research, 1986, Jul-15, Volume: 43, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Imidazoles; Male; Rabbits; Thrombocytopenia; Thrombosis; Thromboxane B2; Time Factors

1986
Direct and indirect effects of leukotriene D4 on the lungs of unanesthetized sheep.
    Respiration; international review of thoracic diseases, 1987, Volume: 51, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Anesthesia; Animals; Arachidonate 5-Lipoxygenase; Blood Pressure; Female; Hypertension, Pulmonary; Ibuprofen; Imidazoles; Lung; Lung Compliance; Lymph; Male; Meclofenamic Acid; Prostaglandin-Endoperoxide Synthases; Pulmonary Wedge Pressure; Sheep; SRS-A; Thromboxane B2; Thromboxane-A Synthase

1987
Systemic and regional hemodynamic effects of cyclo-oxygenase and thromboxane synthetase inhibition in normal and hyperdynamic endotoxemic rabbits.
    Circulatory shock, 1988, Volume: 26, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cyclooxygenase Inhibitors; Disease Models, Animal; Endotoxins; Escherichia coli; Hemodynamics; Imidazoles; Indomethacin; Lipopolysaccharides; Male; Prostaglandins; Rabbits; Shock, Septic; Thromboxane A2; Thromboxane-A Synthase

1988
Pharmacologic modification of blood flow in the rabbit microvasculature with prostacyclin and related drugs.
    Plastic and reconstructive surgery, 1985, Volume: 75, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Abdominal Muscles; Animals; Blood Flow Velocity; Blood Pressure; Cyclooxygenase Inhibitors; Epoprostenol; Imidazoles; Indomethacin; Microcirculation; Platelet Aggregation; Pyrazoles; Pyrazolones; Rabbits; Regional Blood Flow; Surgical Flaps; Thromboxane-A Synthase; Vasoconstriction; Vasodilation

1985
Effects of a specific thromboxane synthetase inhibitor in equine endotoxaemia.
    Research in veterinary science, 1987, Volume: 43, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Endotoxins; Escherichia coli; Female; Horses; Imidazoles; Male; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase

1987
Acid infusion elicits thromboxane A2-mediated effects on respiration and pulmonary hemodynamics in the cat.
    Respiration physiology, 1988, Volume: 71, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Cats; Female; Hydrochloric Acid; Imidazoles; Infusions, Intravenous; Male; Prostaglandin Endoperoxides, Synthetic; Pulmonary Circulation; Respiration; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase

1988
High protein intake stimulates glomerular prostaglandin formation in remnant kidneys.
    The American journal of physiology, 1987, Volume: 252, Issue:6 Pt 2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Body Weight; Dietary Proteins; Dinoprostone; Imidazoles; Indomethacin; Inulin; Kidney Glomerulus; Organ Size; Prostaglandins; Prostaglandins E; Rats; Rats, Inbred Strains; Thromboxane B2

1987
Effect of a thromboxane synthetase inhibitor on eicosanoid synthesis and glomerular injury during acute unilateral glomerulonephritis in the rat.
    Clinical nephrology, 1986, Volume: 26, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Dinoprostone; Glomerulonephritis; Imidazoles; Kidney Glomerulus; Prostaglandins E; Radioimmunoassay; Rats; Rats, Inbred Lew; Thromboxane B2; Thromboxane-A Synthase

1986
Effects of flunixin meglumine, phenylbutazone and a selective thromboxane synthetase inhibitor (UK-38,485) on thromboxane and prostacyclin production in healthy horses.
    Research in veterinary science, 1986, Volume: 40, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Clonixin; Epoprostenol; Horses; Imidazoles; Male; Nicotinic Acids; Orchiectomy; Phenylbutazone; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase

1986
Formation of prostanoids in human umbilical vessels perfused in vitro.
    Prostaglandins, 1986, Volume: 31, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Dinoprost; Dinoprostone; Humans; Imidazoles; Immunologic Techniques; In Vitro Techniques; Indomethacin; Prostaglandins; Prostaglandins E; Prostaglandins F; Radioimmunoassay; Thromboxane B2; Umbilical Arteries; Umbilical Veins

1986
Thromboxane A2 and prostacyclin do not modulate pulmonary hemodynamics during exercise in sheep.
    Journal of applied physiology (Bethesda, Md. : 1985), 1986, Volume: 61, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Cardiac Output; Epoprostenol; Hemodynamics; Hypoxia; Ibuprofen; Imidazoles; Lung; Lymph; Meclofenamic Acid; Physical Exertion; Pulmonary Artery; Sheep; Thromboxane A2; Vascular Resistance

1986
Cortical and vascular prostaglandin synthesis during renal allograft rejection in the rat.
    Transplantation, 1987, Volume: 43, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Platelets; Blood Vessels; Creatinine; Graft Rejection; Imidazoles; Indomethacin; Kidney; Kidney Cortex; Kidney Transplantation; Prostaglandins; Rats; Rats, Inbred Strains; Thromboxane B2

1987
A high plasma prostaglandin to thromboxane ratio protects against renal ischemia.
    Surgery, gynecology & obstetrics, 1987, Volume: 165, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Benzofurans; Creatinine; Evaluation Studies as Topic; Ibuprofen; Imidazoles; Ischemia; Kidney; Kidney Tubular Necrosis, Acute; Male; Methacrylates; Pyridines; Rats; Thromboxane B2; Thromboxane-A Synthase

1987
Involvement of thromboxane in injury to isolated rat lungs perfused with phorbol myristate acetate in the presence and absence of neutrophils.
    Toxicology and applied pharmacology, 1987, Volume: 91, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Imidazoles; Indomethacin; Lung; Male; Neutrophils; Organ Size; Perfusion; Pressure; Pulmonary Edema; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Thromboxane B2; Thromboxane-A Synthase

1987
Survival of mice with NC carcinoma is unchanged by drugs that are thought to inhibit thromboxane synthesis or increase prostacyclin formation.
    British journal of cancer, 1986, Volume: 54, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Antineoplastic Agents; Female; Imidazoles; Mammary Neoplasms, Experimental; Mice; Prostaglandins E; Pyrazoles; Pyrazolones; Thromboxane B2; Thromboxane-A Synthase

1986
Delayed thromboxane or tumor necrosis factor-alpha, but not leukotriene inhibition, attenuates prolonged pulmonary hypertension in endotoxemia.
    The American journal of the medical sciences, 1995, Volume: 310, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Endotoxins; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Imidazoles; Leukotriene Antagonists; Leukotrienes; Lipoxygenase; Masoprocol; Pentoxifylline; Sepsis; Swine; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Toxemia; Tumor Necrosis Factor-alpha

1995
Capsular type-specific polysaccharide partially inhibits group B Streptococcus-induced pulmonary hypertension.
    The American review of respiratory disease, 1993, Volume: 148, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Analysis of Variance; Animals; Bacterial Capsules; Disease Models, Animal; Drug Evaluation, Preclinical; Hemodynamics; Hypertension, Pulmonary; Imidazoles; Polysaccharides, Bacterial; Streptococcal Infections; Streptococcus agalactiae; Swine; Thromboxane B2; Thromboxane-A Synthase

1993
Effects of a thromboxane synthetase inhibitor on platelet function; possible risks of use in pregnancy.
    Prostaglandins, 1993, Volume: 46, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Blood Platelets; Cells, Cultured; Collagen; Contraindications; Dinoprostone; Eicosanoids; Female; Humans; Imidazoles; Platelet Aggregation; Pregnancy; Thromboxane B2; Thromboxane-A Synthase

1993
Chronic thromboxane synthase inhibition prevents fructose-induced hypertension.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta; Blood Glucose; Blood Pressure; Enzyme Inhibitors; Epoprostenol; Fructose; Hypertension; Imidazoles; Insulin; Rats; Rats, Wistar; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes; Triglycerides

2001