dauricine has been researched along with ketoconazole in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, X; Wang, Y; Zheng, J; Zhong, D | 1 |
| Chen, X; Dai, J; Gu, Y; Jin, H; Liu, J; Zheng, J; Zhong, D | 1 |
| Chen, X; Jin, H; Shen, S; Zheng, J; Zhong, D | 1 |
3 other study(ies) available for dauricine and ketoconazole
| Article | Year |
|---|---|
Identification of quinone methide metabolites of dauricine in human liver microsomes and in rat bile.
Topics: Administration, Oral; Animals; Benzylisoquinolines; Bile; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Glutathione; Humans; Indolequinones; Ketoconazole; Microsomes, Liver; Rats; Spectrometry, Mass, Electrospray Ionization; Tetrahydroisoquinolines | 2009 |
Pulmonary toxicity and metabolic activation of dauricine in CD-1 mice.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Benzylisoquinolines; Biotransformation; Blood Urea Nitrogen; Bronchoalveolar Lavage Fluid; Cell Line; Cell Membrane; Cell Membrane Permeability; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Hemorrhage; Humans; In Vitro Techniques; Ketoconazole; L-Lactate Dehydrogenase; Lung; Male; Mice; Microsomes; Pulmonary Edema; Recombinant Proteins; Tetrahydroisoquinolines; Tissue Distribution | 2010 |
CYP3A-mediated apoptosis of dauricine in cultured human bronchial epithelial cells and in lungs of CD-1 mice.
Topics: Animals; Apoptosis; bcl-Associated Death Protein; Benzylisoquinolines; Blotting, Western; Bronchi; Buthionine Sulfoximine; Caspase 3; Cell Survival; Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Cytochromes c; Enzyme Inhibitors; Epithelial Cells; Flow Cytometry; Glutathione; Humans; In Situ Nick-End Labeling; Ketoconazole; Lung; Male; Mice; Tetrahydroisoquinolines | 2012 |