Page last updated: 2024-08-23

daunorubicin and razoxane

daunorubicin has been researched along with razoxane in 42 studies

Research

Studies (42)

Timeframe	Studies, this research(%)	All Research%
pre-1990	13 (30.95)	18.7374
1990's	9 (21.43)	18.2507
2000's	18 (42.86)	29.6817
2010's	2 (4.76)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Comelli, A; Massimo, L	1
Ardalan, B; Bier, C; Herman, E; Krop, S; Waravdekar, V	1
Kundv, D; Smith, BJ	1
Ferrans, VJ; Herman, EH	2
Monti, E; Sinha, BK	1
Fischer, VW; Hobart, NH; Wang, GM	1
Creighton, AM; el-Hage, AN; Ferrans, VJ; Herman, EH; Witiak, DT	1
El-Hage, AN; Ferrans, VJ; Herman, EH; Witiak, DT	1
Supino, R	1
Ardalan, B; Ferrans, VJ; Herman, EH; Jordan, W	1
Bruno, S; Macdonald, JS; Marsoni, S; Penta, J; Poster, DS	1
Fischer, VW; LaRose, LS; Wang, GM	1
Finch, M; Wang, GM	1
Finch, MD; Hellmann, K; Trevan, D; Wang, G	1
Demant, EJ; Friche, E; Holm, B; Jensen, PB; Sehested, M; Sørensen, BS	1
Besse, P; Bonoron-Adèle, S; Gouverneur, G; Pouna, P; Robert, J; Tariosse, L	1
Buss, JL; Hasinoff, BB; Ling, Y; Yalowich, JC	1
Lemez, P; Maresová, J	2
Arstall, MA; Fukazawa, R; Kelly, RA; Sawyer, DB	1
Bajgar, J; Cerman, J; Gersl, V; Hrdina, R; Machácková, J; Mazurová, Y; Suba, P	1
Bauer, FK; Burke, BE; Cusack, BJ; Gambliel, H; Olson, RD	1
Jensen, PB; Langer, SW; Sehested, M	1
Hellmann, K; Sargent, JM; Taylor, CG; Williamson, CJ; Yardley, C	1
Budman, DR; Calabro, A; Kreis, W	1
Balwierz, W; Kowalczyk, JR; Styczynski, J; Wysocki, M	1
Adamcová, M; Bukac, J; Gersl, V; Hrdina, R; Klimtová, I; Machácková, J; Simůnek, T; Vávrová, J	1
Higashihara, M; Honma, Y; Niitsu, N	1
Adamcová, M; Gersl, V; Hrdina, R; Klimtová, I; Machácková, J; Mazurová, Y; Simůnek, T	1
Adamcová, M; Gersl, V; Hrdina, R; Kaplanová, J; Klimtová, I; Mazurová, Y; Pelouch, V; Simůnek, T	1
Adamcová, M; Gersl, V; Hrdina, R; Kaplanová, J; Klimtová, I; Mazurová, Y; Simůnek, T; Sterba, M	1
Hasinoff, BB; Wu, X	1
Hofland, KF; Jensen, PB; Sehested, M; Thougaard, AV	1
Jensen, PB; Langer, SW; Sehested, M; Thougaard, AV	1
Blazek, B; Elbl, L; Hrstkova, H; Michalek, J; Tomaskova, I	1
Charlier, H; Cusack, BJ; Gambliel, H; Hadjokas, N; Musser, B; Olson, RD; Shadle, SE	1
Adamcová, M; Čajnáková, H; Gersl, V; Hrbatová, L; Ponka, P; Popelová, O; Potáčová, A; Šimůnek, T; Sterba, M	1
Bárdi, E; Bobok, I; Kappelmayer, J; Kiss, C; V Oláh, A	1
Adamcová, M; Aupperle, H; Geršl, V; Mazurová, Y; Popelová, O; Potáčová, A; Štěrba, M	1
Adamcová, M; Geršl, V; Hroch, M; Jirkovský, E; Lenčová-Popelová, O; Mazurová, Y; Mičuda, S; Šimůnek, T; Štěrba, M; Vávrová, J	1

Trials

3 trial(s) available for daunorubicin and razoxane

Article	Year
Bis-diketopiperazine derivatives in clinical oncology: ICRF-159. Cancer clinical trials, 1980, Volume: 3, Issue:4 Topics: Animals; Antineoplastic Agents; Clinical Trials as Topic; Daunorubicin; Doxorubicin; Drug Evaluation; Drug Interactions; Head and Neck Neoplasms; Humans; Lymphoma; Mice; Neoplasm Metastasis; Neoplasms; Piperazines; Razoxane	1980
Efficacy of dexrazoxane as a cardioprotective agent in patients receiving mitoxantrone- and daunorubicin-based chemotherapy. Seminars in oncology, 1998, Volume: 25, Issue:4 Suppl 10 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cardiovascular Agents; Daunorubicin; Female; Heart Diseases; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Razoxane	1998
Long-term serial echocardiographic examination of late anthracycline cardiotoxicity and its prevention by dexrazoxane in paediatric patients. European journal of pediatrics, 2005, Volume: 164, Issue:11 Topics: Adolescent; Anthracyclines; Antineoplastic Agents; Blood Pressure; Body Mass Index; Cardiovascular Agents; Child; Child, Preschool; Czech Republic; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Echocardiography, Stress; Female; Follow-Up Studies; Heart; Heart Rate; Humans; Infant; Male; Neoplasms; Prospective Studies; Razoxane; Time Factors; Treatment Outcome	2005

Other Studies

39 other study(ies) available for daunorubicin and razoxane

Article	Year
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
[New drugs for the therapy of acute leukemia]. Minerva medica, 1975, Jul-28, Volume: 66, Issue:52 Topics: Acute Disease; Antineoplastic Agents; Azacitidine; Cytarabine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Guanazole; Humans; Leukemia; Lomustine; Peptichemio; Podophyllotoxin; Razoxane; Zinostatin	1975
Reduction of daunorubicin lethality and myocardial cellular alterations by pretreatment with ICRF-187 in Syrian golden hamsters. Cancer treatment reports, 1979, Volume: 63, Issue:1 Topics: Animals; Body Weight; Chemical and Drug Induced Liver Injury; Cricetinae; Daunorubicin; Heart Diseases; Liver; Liver Diseases; Male; Mesocricetus; Myocardium; Piperazines; Rats; Razoxane; Stereoisomerism; Time Factors	1979
Letter: Digoxin does not prevent daunorubicin or adriamycin from binding to rat heart muscle. British journal of cancer, 1976, Volume: 33, Issue:2 Topics: Animals; Binding Sites; Daunorubicin; Digitoxin; Digoxin; Doxorubicin; Heart; Male; Myocardium; Propranolol; Rats; Razoxane	1976
Examination of the potential long-lasting protective effect of ICRF-187 against anthracycline-induced chronic cardiomyopathy. Cancer treatment reviews, 1990, Volume: 17, Issue:2-3 Topics: Animals; Cardiomyopathies; Chronic Disease; Daunorubicin; Male; Myocardium; Myofibrils; Rabbits; Razoxane; Time Factors; Vacuoles	1990
Potentiation of doxorubicin cytotoxicity by (+)-1,2-bis-(3,5-dioxopiperazinyl-1-yl) propane (ICRF-187) in human leukemic HL-60 cells. Cancer communications, 1990, Volume: 2, Issue:4 Topics: Biological Transport; Cell Line; Cell Survival; Daunorubicin; Doxorubicin; Drug Synergism; Electron Spin Resonance Spectroscopy; Humans; Leukemia, Promyelocytic, Acute; Piperazines; Razoxane; Stereoisomerism; Tumor Cells, Cultured	1990
Mitigation of an anthracycline-induced cardiomyopathy by pretreatment with razoxane: a quantitative morphological assessment. Virchows Archiv. B, Cell pathology including molecular pathology, 1986, Volume: 51, Issue:4 Topics: Animals; Cardiomyopathies; Daunorubicin; Drug Administration Schedule; Intracellular Membranes; Male; Mice; Microscopy, Electron; Mitochondria, Heart; Myocardium; Piperazines; Razoxane; Sarcoplasmic Reticulum; Time Factors	1986
Pretreatment with ICRF-187 provides long-lasting protection against chronic daunorubicin cardiotoxicity in rabbits. Cancer chemotherapy and pharmacology, 1986, Volume: 16, Issue:2 Topics: Animals; Blood Cell Count; Body Weight; Cardiomyopathies; Daunorubicin; Drug Administration Schedule; Drug Interactions; Hemoglobins; Injections, Intraperitoneal; Injections, Intravenous; Male; Piperazines; Rabbits; Razoxane	1986
Comparison of the protective effect of ICRF-187 and structurally related analogues against acute daunorubicin toxicity in Syrian golden hamsters. Research communications in chemical pathology and pharmacology, 1985, Volume: 48, Issue:1 Topics: Animals; Body Weight; Cricetinae; Daunorubicin; Male; Mesocricetus; Piperazines; Razoxane; Stereoisomerism; Structure-Activity Relationship	1985
Reduction by ICRF-187 of acute daunorubicin toxicity in Syrian golden hamsters. Research communications in chemical pathology and pharmacology, 1983, Volume: 40, Issue:2 Topics: Animals; Body Weight; Cricetinae; Daunorubicin; Male; Mesocricetus; Piperazines; Razoxane; Time Factors	1983
Influence of ICRF-159 or ICRF-186 on cytotoxicity of daunorubicin and doxorubicin. Tumori, 1984, Apr-30, Volume: 70, Issue:2 Topics: Colony-Forming Units Assay; Daunorubicin; Doxorubicin; Drug Synergism; HeLa Cells; Humans; In Vitro Techniques; Piperazines; Razoxane; Stereoisomerism	1984
Reduction of chronic daunorubicin cardiotoxicity by ICRF-187 in rabbits. Research communications in chemical pathology and pharmacology, 1981, Volume: 31, Issue:1 Topics: Animals; Antineoplastic Agents; Blood Chemical Analysis; Body Weight; Calcium; Daunorubicin; Heart; Male; Myocardium; Piperazines; Rabbits; Razoxane	1981
Mitigating effects of ICRF-159 (razoxane) on a daunomycin-induced cardiomyopathy in mice. Drug and chemical toxicology, 1982, Volume: 5, Issue:2 Topics: Animals; Cardiomyopathies; Daunorubicin; Mice; Myocardium; Piperazines; Razoxane	1982
Effect of razoxane (ICRF 159) on daunomycin (NSC 82151) metabolism and DNA complexation. Drug and chemical toxicology, 1980, Volume: 3, Issue:2 Topics: Animals; Daunorubicin; DNA; Doxorubicin; In Vitro Techniques; Liver; Male; Mice; Piperazines; Rats; Razoxane	1980
Reduction of daunomycin toxicity by razoxane. British journal of cancer, 1981, Volume: 43, Issue:6 Topics: Animals; Body Weight; Daunorubicin; Dose-Response Relationship, Drug; Female; Intestines; Mice; Piperazines; Razoxane	1981
Antagonistic effect of the cardioprotector (+)-1,2-bis(3,5-dioxopiperazinyl-1-yl)propane (ICRF-187) on DNA breaks and cytotoxicity induced by the topoisomerase II directed drugs daunorubicin and etoposide (VP-16). Biochemical pharmacology, 1993, Aug-03, Volume: 46, Issue:3 Topics: Cell Survival; Daunorubicin; DNA Damage; DNA Topoisomerases, Type II; DNA, Single-Stranded; Drug Interactions; Etoposide; Humans; Razoxane; Tumor Cells, Cultured	1993
Development of the model of rat isolated perfused heart for the evaluation of anthracycline cardiotoxicity and its circumvention. British journal of pharmacology, 1996, Volume: 117, Issue:7 Topics: Animals; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Cancer, Regional Perfusion; Daunorubicin; Drug Evaluation, Preclinical; Heart; Heart Diseases; In Vitro Techniques; Liposomes; Male; Myocardium; Rats; Rats, Sprague-Dawley; Razoxane; Ventricular Function, Left; Ventricular Pressure	1996
The effect of dexrazoxane (ICRF-187) on doxorubicin- and daunorubicin-mediated growth inhibition of Chinese hamster ovary cells. Anti-cancer drugs, 1996, Volume: 7, Issue:5 Topics: Animals; Antineoplastic Agents; Cell Division; CHO Cells; Cricetinae; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Drug Antagonism; Drug Synergism; Razoxane	1996
Protective effects of cardioxane against anthracycline-induced cardiotoxicity in relapsed acute myeloid leukemias. Neoplasma, 1996, Volume: 43, Issue:6 Topics: Acute Disease; Antibiotics, Antineoplastic; Antineoplastic Agents; Cardiovascular Agents; Cytarabine; Daunorubicin; Female; Heart; Humans; Leukemia, Myeloid; Male; Middle Aged; Razoxane; Recurrence	1996
Daunorubicin-induced apoptosis in rat cardiac myocytes is inhibited by dexrazoxane. Circulation research, 1999, Feb-19, Volume: 84, Issue:3 Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Cardiovascular Agents; Cells, Cultured; Daunorubicin; Dose-Response Relationship, Drug; Heart; Necrosis; Oxidative Stress; Rats; Rats, Sprague-Dawley; Razoxane; Superoxides	1999
Cholinesterases in dexrazoxane-treated daunorubicin cardiomyopathy in rabbits. General physiology and biophysics, 1999, Volume: 18, Issue:4 Topics: Acetylcholinesterase; Animals; Antibiotics, Antineoplastic; Body Weight; Butyrylcholinesterase; Cardiomyopathies; Cardiovascular Agents; Daunorubicin; Heart; Male; Myocardium; Rabbits; Razoxane; Ventricular Function, Left	1999
Prevention by dexrazoxane of down-regulation of ryanodine receptor gene expression in anthracycline cardiomyopathy in the rat. British journal of pharmacology, 2000, Volume: 131, Issue:1 Topics: Animals; Antibiotics, Antineoplastic; Cardiomyopathies; Daunorubicin; Down-Regulation; Gene Expression Regulation; Glyceraldehyde-3-Phosphate Dehydrogenases; Male; Rats; Rats, Inbred F344; Razoxane; RNA, Messenger; Ryanodine Receptor Calcium Release Channel	2000
Treatment of anthracycline extravasation with dexrazoxane. Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:9 Topics: Animals; Antibiotics, Antineoplastic; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Enzyme Inhibitors; Extravasation of Diagnostic and Therapeutic Materials; Female; Idarubicin; Mice; Razoxane; Skin Diseases; Topoisomerase II Inhibitors	2000
Dexrazoxane significantly impairs the induction of doxorubicin resistance in the human leukaemia line, K562. British journal of cancer, 2001, Apr-06, Volume: 84, Issue:7 Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporins; Daunorubicin; Doxorubicin; Drug Interactions; Drug Resistance, Neoplasm; Gene Expression Regulation; Humans; K562 Cells; Phenotype; Razoxane; RNA, Messenger	2001
In vitro effects of dexrazoxane (Zinecard) and classical acute leukemia therapy: time to consider expanded clinical trials? Leukemia, 2001, Volume: 15, Issue:10 Topics: Acute Disease; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cell Death; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Humans; Inhibitory Concentration 50; Leukemia; Mitoxantrone; Razoxane; Tumor Cells, Cultured	2001
Dexrazoxane has no impact on sensitivity of childhood leukemic blasts to daunorubicin. Leukemia, 2002, Volume: 16, Issue:5 Topics: Adolescent; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Survival; Child; Child, Preschool; Daunorubicin; Drug Interactions; Drug Resistance, Neoplasm; Flow Cytometry; HL-60 Cells; Humans; Infant; K562 Cells; Leukemia; Razoxane; Tumor Cells, Cultured	2002
Troponins in experimental studies. Acta medica (Hradec Kralove), 2002, Volume: 45, Issue:1 Topics: Animals; Antibiotics, Antineoplastic; Biomarkers; Cardiomyopathies; Daunorubicin; Heart; Male; Protective Agents; Rabbits; Razoxane; Troponin T	2002
The catalytic DNA topoisomerase II inhibitor ICRF-193 and all-trans retinoic acid cooperatively induce granulocytic differentiation of acute promyelocytic leukemia cells: candidate drugs for chemo-differentiation therapy against acute promyelocytic leukem Experimental hematology, 2002, Volume: 30, Issue:11 Topics: Antineoplastic Agents; Catalysis; Cell Cycle; Cell Differentiation; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cytarabine; Daunorubicin; Deoxycytidine; Diketopiperazines; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Inhibitors; Granulocytes; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Neoplasm Proteins; Neoplastic Stem Cells; Piperazines; Razoxane; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; RNA, Messenger; RNA, Neoplasm; Topoisomerase II Inhibitors; Tretinoin; Tumor Cells, Cultured; U937 Cells	2002
Effect of sodium 2,3-dimercaptopropane-1-sulphonate (DMPS) on chronic daunorubicin toxicity in rabbits: comparison with dexrazoxane. Acta medica (Hradec Kralove), 2002, Volume: 45, Issue:3 Topics: Animals; Antibiotics, Antineoplastic; Calcium; Chelating Agents; Daunorubicin; Heart; Iron; Male; Myocardium; Rabbits; Razoxane; Unithiol	2002
Protein profiling in daunorubicin-induced cardiomyopathy. General physiology and biophysics, 2003, Volume: 22, Issue:3 Topics: Animals; Antibiotics, Antineoplastic; Cardiomyopathies; Cardiotonic Agents; Daunorubicin; Heart Ventricles; Male; Proteins; Rabbits; Razoxane	2003
Rabbit model for in vivo study of anthracycline-induced heart failure and for the evaluation of protective agents. European journal of heart failure, 2004, Volume: 6, Issue:4 Topics: Animals; Anthracyclines; Antibiotics, Antineoplastic; Biomarkers; Body Weight; Cardiovascular Agents; Daunorubicin; Disease Models, Animal; Dose-Response Relationship, Drug; Echocardiography; Erythrocyte Indices; Heart Failure; Heart Rate; Heart Ventricles; Male; Models, Cardiovascular; Myocardium; Myocytes, Cardiac; Rabbits; Razoxane; Stroke Volume; Time Factors	2004
The antitumor anthracyclines doxorubicin and daunorubicin do not inhibit cell growth through the formation of iron-mediated reactive oxygen species. Anti-cancer drugs, 2005, Volume: 16, Issue:1 Topics: Animals; Anthracyclines; Antibiotics, Antineoplastic; Cardiovascular Agents; Cell Culture Techniques; Cell Proliferation; Daunorubicin; Doxorubicin; Enzyme Inhibitors; Iron; Models, Animal; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Razoxane; Reactive Oxygen Species; Topoisomerase II Inhibitors	2005
Dexrazoxane protects against myelosuppression from the DNA cleavage-enhancing drugs etoposide and daunorubicin but not doxorubicin. Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, May-15, Volume: 11, Issue:10 Topics: Anemia; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Cardiovascular Agents; Cell Culture Techniques; Colony-Forming Units Assay; Daunorubicin; Doxorubicin; Etoposide; Female; Leukopenia; Mice; Neutropenia; Razoxane; Thrombocytopenia	2005
Treatment of anthracycline extravasation in mice with dexrazoxane with or without DMSO and hydrocortisone. Cancer chemotherapy and pharmacology, 2006, Volume: 57, Issue:1 Topics: Administration, Topical; Animals; Antibiotics, Antineoplastic; Daunorubicin; Dimethyl Sulfoxide; Drug Therapy, Combination; Extravasation of Diagnostic and Therapeutic Materials; Female; Hydrocortisone; Injections, Intralesional; Injections, Intraperitoneal; Mice; Mice, Inbred Strains; Razoxane	2006
Prevention of chronic anthracycline cardiotoxicity in the adult Fischer 344 rat by dexrazoxane and effects on iron metabolism. Cancer chemotherapy and pharmacology, 2006, Volume: 58, Issue:4 Topics: Animals; Antibiotics, Antineoplastic; Chelating Agents; Daunorubicin; Heart Diseases; Iron Regulatory Protein 1; Iron-Regulatory Proteins; Male; Rats; Rats, Inbred F344; Razoxane	2006
Evaluation of ECG time intervals in a rabbit model of anthracycline-induced cardiomyopathy: a useful tool for assessment of cardioprotective agents. Physiological research, 2007, Volume: 56, Issue:2 Topics: Aldehydes; Animals; Cardiomyopathies; Cardiotonic Agents; Chronic Disease; Daunorubicin; Disease Models, Animal; Drug Evaluation, Preclinical; Electrocardiography; Heart Conduction System; Hydrazones; Iron Chelating Agents; Male; Myocardial Contraction; Pyridoxal; Rabbits; Razoxane; Time Factors; Troponin T	2007
Anthracycline antibiotics induce acute renal tubular toxicity in children with cancer. Pathology oncology research : POR, 2007, Volume: 13, Issue:3 Topics: Acetylglucosaminidase; Adolescent; Adult; Albuminuria; Anthracyclines; Antibiotics, Antineoplastic; Antineoplastic Agents; Child; Child, Preschool; Creatinine; Daunorubicin; Doxorubicin; Epirubicin; Female; Humans; Idarubicin; Infant; Kidney Diseases; Kidney Tubules, Proximal; Lymphoma, Non-Hodgkin; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Razoxane; Retrospective Studies	2007
Cardiac remodeling and MMPs on the model of chronic daunorubicin-induced cardiomyopathy in rabbits. Physiological research, 2010, Volume: 59, Issue:5 Topics: Animals; Antibiotics, Antineoplastic; Cardiomyopathies; Cardiovascular Agents; Chronic Disease; Collagen; Daunorubicin; Disease Models, Animal; Drug Interactions; Fibrosis; Hydroxyproline; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Myocardium; Rabbits; Razoxane; Ventricular Remodeling	2010
Early and delayed cardioprotective intervention with dexrazoxane each show different potential for prevention of chronic anthracycline cardiotoxicity in rabbits. Toxicology, 2013, Sep-15, Volume: 311, Issue:3 Topics: Animals; Antibiotics, Antineoplastic; Cardiotonic Agents; Citrate (si)-Synthase; Daunorubicin; Heart Diseases; Male; NF-E2-Related Factor 2; Oxidative Stress; Rabbits; Razoxane; Troponin T; Ventricular Function, Left	2013