Compounds > daunorubicin
Page last updated: 2024-08-23

daunorubicin and piperidines

daunorubicin has been researched along with piperidines in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (40.00)18.2507
2000's5 (25.00)29.6817
2010's7 (35.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Berlion, M; Dieterlen, A; Lucas, C; Marchal, S; Merlin, JL; Poullain, MG; Ramacci, C; Schultz, G1
Lucas, C; Marchal, S; Merlin, JL; Paraire, M; Poullain, MG; Ramacci, C1
Berlion, M; Kernaleguen, D; Le Bot, MA; Riché, C; Simon, I1
Demmer, A; Dunn, T; Hoof, T; Kubesch, P; Tümmler, B1
Ford, PJ; Germann, UA; Harding, MW; Mason, VS; Shlyakhter, D1
Cayre, A; Finat-Duclos, F; Maublant, J; Moins, N; Verrelle, P2
Bour-Dill, C; Giroux, B; Marchal, S; Merlin, JL; Poullain, MG; Ramacci, C1
Casciano, CN; Clement, RP; Johnson, WW; Wang, E1
Bishop, WR; Nakajima, A; Ohyashiki, K; Sumi, M; Tauchi, T1
Azzam, K; Hasmann, M; Nüssler, V; Pelka-Fleischer, R; Pogrebniak, A; Schemainda, I1
Karp, J1
Briel, J; Gocke, CD; Hess, AD; Kanakry, CG; Karp, JE; Kos, F; Levitsky, H; Luznik, L; Meyer, C; Smith, BD; Thoburn, C1
Bolaños-Meade, J; Villela, L1
Boddy, N; Burrows, F; Pallis, M; Russell, N; Seedhouse, C; Whittall, A1
Blackford, AL; Bose, P; Doyle, LA; Foster, MC; Gocke, CD; Gojo, I; Karp, JE; Lancet, JE; Levy, MY; Little, RF; Litzow, MR; Morris, LE; Rosner, GL; Smith, BD; Strickland, SA; Tibes, R; Wright, JJ; Zeidner, JF2
Abdul-Aziz, A; Bowles, KM; Lawes, M; MacEwan, DJ; Pillinger, G; Rushworth, SA; Zaitseva, L1
Gronda, M; Hurren, R; Minden, MD; Rotin, LE; Schimmer, AD; Slassi, M; Wang, X1

Reviews

1 review(s) available for daunorubicin and piperidines

ArticleYear
Acute myeloid leukaemia: optimal management and recent developments.
    Drugs, 2011, Aug-20, Volume: 71, Issue:12

    Topics: Adenine Nucleotides; Antibodies, Monoclonal; Antineoplastic Agents; Arabinonucleosides; Clofarabine; Daunorubicin; Flavonoids; Humans; Leukemia, Myeloid, Acute; Piperidines

2011

Trials

2 trial(s) available for daunorubicin and piperidines

ArticleYear
Randomized multicenter phase II study of flavopiridol (alvocidib), cytarabine, and mitoxantrone (FLAM) versus cytarabine/daunorubicin (7+3) in newly diagnosed acute myeloid leukemia.
    Haematologica, 2015, Volume: 100, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Flavonoids; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Piperidines; Survival Rate

2015
Final results of a randomized multicenter phase II study of alvocidib, cytarabine, and mitoxantrone versus cytarabine and daunorubicin (7 + 3) in newly diagnosed high-risk acute myeloid leukemia (AML).
    Leukemia research, 2018, Volume: 72

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Flavonoids; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Piperidines; Risk Factors

2018

Other Studies

17 other study(ies) available for daunorubicin and piperidines

ArticleYear
Influence of S9788, a new modulator of multidrug resistance, on the cellular accumulation and subcellular distribution of daunorubicin in P-glycoprotein-expressing MCF7 human breast adenocarcinoma cells.
    Cytometry, 1995, Aug-01, Volume: 20, Issue:4

    Topics: Adenocarcinoma; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Cell Nucleus; Cyclosporine; Daunorubicin; Drug Resistance, Multiple; Female; Flow Cytometry; Humans; Neoplasm Proteins; Piperidines; Subcellular Fractions; Triazines; Tumor Cells, Cultured; Verapamil

1995
[Effect of the modality of exposure on the action of S9788 on the modulation of multidrug resistance of human tumor cell lines].
    Bulletin du cancer, 1994, Volume: 81, Issue:10

    Topics: Adenocarcinoma; Antineoplastic Agents; Breast Neoplasms; Cyclosporine; Daunorubicin; Drug Resistance, Multiple; Humans; Leukemia; Piperidines; Triazines; Tumor Cells, Cultured; Verapamil

1994
[Pharmacological properties of S9788, a new modulator of multidrug resistance].
    Bulletin du cancer, 1994, Volume: 81, Issue:2

    Topics: Adjuvants, Immunologic; Antineoplastic Agents; Cyclosporine; Daunorubicin; Doxorubicin; Drug Resistance, Multiple; Humans; Piperidines; Spectrometry, Fluorescence; Triazines; Tumor Cells, Cultured; Vinblastine; Vincristine

1994
[Effect of S9788, cyclosporin A and verapamil on intracellular accumulation of doxorubicin, daunorubicin and daunorubicinol in primary rat hepatocyte culture].
    Annales de biologie clinique, 1996, Volume: 54, Issue:1

    Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Cyclosporine; Daunorubicin; Doxorubicin; Drug Resistance, Multiple; Liver; Piperidines; Rats; Rats, Sprague-Dawley; Triazines; Verapamil

1996
Competitive inhibition of photoaffinity labelling of P-glycoprotein by anticancer drugs and modulators including S9788.
    European journal of pharmacology, 1996, Nov-21, Volume: 315, Issue:3

    Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cricetinae; Daunorubicin; Drug Resistance, Multiple; Piperidines; Triazines

1996
Chemosensitization and drug accumulation effects of VX-710, verapamil, cyclosporin A, MS-209 and GF120918 in multidrug resistant HL60/ADR cells expressing the multidrug resistance-associated protein MRP.
    Anti-cancer drugs, 1997, Volume: 8, Issue:2

    Topics: Acridines; Affinity Labels; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Cyclosporine; Daunorubicin; Doxorubicin; Drug Resistance, Multiple; Etoposide; Fluoresceins; HL-60 Cells; Humans; Isoquinolines; Multidrug Resistance-Associated Proteins; Piperidines; Pyridines; Quinolines; Tetrahydroisoquinolines; Tritium; Verapamil; Vincristine

1997
Comparison between technetium-99m-sestamibi and hydrogen-3-daunomycin myocardial cellular retention in vitro.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1997, Volume: 38, Issue:11

    Topics: Animals; Animals, Newborn; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Cyclosporins; Daunorubicin; Drug Resistance, Neoplasm; Genes, MDR; Heart; In Vitro Techniques; Myocardium; Piperidines; Radionuclide Imaging; Rats; Rats, Wistar; Technetium Tc 99m Sestamibi; Triazines; Tritium; Verapamil

1997
Comparative 99mTc-sestamibi and 3H-daunomycin uptake in human carcinoma cells: relation to the MDR phenotype and effects of reversing agents.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1999, Volume: 40, Issue:4

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Cyclosporins; Daunorubicin; Drug Resistance, Multiple; Humans; Piperidines; Radiopharmaceuticals; Reverse Transcriptase Polymerase Chain Reaction; Technetium Tc 99m Sestamibi; Triazines; Tritium; Tumor Cells, Cultured; Verapamil

1999
Modulation of daunorubicin cellular resistance by combination of P-glycoprotein blockers acting on drug efflux and intracellular drug sequestration in Golgi vesicles.
    Cytometry, 2000, Sep-01, Volume: 41, Issue:1

    Topics: Adenocarcinoma; Antibiotics, Antineoplastic; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; beta 2-Microglobulin; Biological Transport; Breast Neoplasms; Cyclosporins; Daunorubicin; DNA Primers; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Gene Expression Regulation, Neoplastic; Golgi Apparatus; Humans; Microscopy, Fluorescence; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Phenotype; Piperidines; Triazines; Tumor Cells, Cultured; Vault Ribonucleoprotein Particles

2000
The farnesyl protein transferase inhibitor SCH66336 is a potent inhibitor of MDR1 product P-glycoprotein.
    Cancer research, 2001, Oct-15, Volume: 61, Issue:20

    Topics: 3T3 Cells; Adenosine Triphosphate; Alkyl and Aryl Transferases; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Cell Line; CHO Cells; Cricetinae; Daunorubicin; Drug Synergism; Enzyme Inhibitors; Farnesyltranstransferase; Genes, MDR; Humans; Hydrolysis; Mice; Paclitaxel; Piperidines; Pyridines; Rhodamine 123; Tamoxifen; Vinblastine

2001
Efficacy of SCH66336, a farnesyl transferase inhibitor, in conjunction with imatinib against BCR-ABL-positive cells.
    Molecular cancer therapeutics, 2003, Volume: 2, Issue:3

    Topics: Alkyl and Aryl Transferases; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzamides; Cell Division; Colony-Forming Units Assay; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Farnesyltranstransferase; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Interleukin-3; Leukemia, Myeloid, Acute; Piperazines; Piperidines; Protein-Tyrosine Kinases; Pyridines; Pyrimidines; Transfection; Treatment Outcome; Tumor Cells, Cultured

2003
Chemopotentiating effects of a novel NAD biosynthesis inhibitor, FK866, in combination with antineoplastic agents.
    European journal of medical research, 2006, Aug-30, Volume: 11, Issue:8

    Topics: Acrylamides; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Cell Death; Cell Line, Tumor; Cell Survival; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Combinations; Humans; K562 Cells; Leukemia, Myeloid, Acute; Melphalan; Methylnitronitrosoguanidine; Monocytes; NAD; Piperidines

2006
Future research directions for the treatment of AML.
    Clinical advances in hematology & oncology : H&O, 2008, Volume: 6, Issue:11

    Topics: Antineoplastic Agents; Azacitidine; Biomedical Research; Carbazoles; Carboplatin; Cytarabine; Daunorubicin; Decitabine; Enzyme Inhibitors; Etoposide; Flavonoids; Furans; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Piperidines; Quinolones; Staurosporine; Topotecan; Tretinoin

2008
Early lymphocyte recovery after intensive timed sequential chemotherapy for acute myelogenous leukemia: peripheral oligoclonal expansion of regulatory T cells.
    Blood, 2011, Jan-13, Volume: 117, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cell Separation; Cytarabine; Cytosine; Daunorubicin; Etoposide; Female; Flavonoids; Flow Cytometry; Gene Expression Profiling; Humans; Immunophenotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Piperidines; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocyte Subsets; T-Lymphocytes, Regulatory; Vidarabine; Young Adult

2011
Efficacy of RNA polymerase II inhibitors in targeting dormant leukaemia cells.
    BMC pharmacology & toxicology, 2013, Jun-15, Volume: 14

    Topics: Acute Disease; Adenine Nucleotides; Antineoplastic Agents; Apoptosis; Arabinonucleosides; Azacitidine; Cell Line, Tumor; Cell Survival; Clofarabine; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Etoposide; Flavonoids; Heterocyclic Compounds, 4 or More Rings; Humans; Leukemia, Myeloid; Piperidines; Purines; RNA Polymerase II; RNA, Neoplasm; Roscovitine; Sirolimus; TOR Serine-Threonine Kinases

2013
Targeting BTK for the treatment of FLT3-ITD mutated acute myeloid leukemia.
    Scientific reports, 2015, Aug-21, Volume: 5

    Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Apoptosis; Blast Crisis; Cell Line, Tumor; Cell Survival; Daunorubicin; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Mutation; Piperidines; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Pyrazoles; Pyrimidines; RNA, Small Interfering; Signal Transduction

2015
Investigating the synergistic mechanism between ibrutinib and daunorubicin in acute myeloid leukemia cells.
    Leukemia & lymphoma, 2016, Volume: 57, Issue:10

    Topics: Adenine; Cytarabine; Daunorubicin; Leukemia, Myeloid, Acute; Piperidines; Pyrazoles; Pyrimidines

2016