daunorubicin has been researched along with mitoxantrone in 318 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 42 (13.21) | 18.7374 |
| 1990's | 114 (35.85) | 18.2507 |
| 2000's | 100 (31.45) | 29.6817 |
| 2010's | 56 (17.61) | 24.3611 |
| 2020's | 6 (1.89) | 2.80 |
| Authors | Studies |
|---|---|
| Angier, RB; Child, RG; Citarella, RV; Durr, FE; Fabio, PF; Murdock, KC; Wallace, RE | 1 |
| Denny, WA; Feigon, J; Kearns, DR; Leupin, W | 1 |
| Barrows, LR; Ireland, CM; Kokoshka, JM | 1 |
| Strassburg, CP; Tukey, RH | 1 |
| Bates, S; Litman, T; Nagy, Z; Ozvegy, C; Sarkadi, B; Szakács, G; Váradi, A | 1 |
| Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA | 1 |
| Baguley, BC; Deady, LW; Denny, WA; Rodemann, T; Zhuang, L | 1 |
| Bauer, KS; Doyle, LA; Fang, HB; Hassel, B; Nakanishi, T; Pumplin, DW; Ross, DD; Wei, Y; Wu, S | 1 |
| Gibbons, S; Kaatz, GW; Zloh, M | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Burkett, BA; Chan, KF; Chan, TH; Chow, LM; Wong, IL; Zhao, Y | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Benfenati, E; Raska, I; Toropov, AA; Toropova, AP | 1 |
| Ghosh, I; Manoharlal, R; Prakash, O; Prasad, R; Puri, N; Sharma, M | 1 |
| Ahn, G; Bailly, C; Baldeyrou, B; Couture, A; Goossens, JF; Grandclaudon, P; Lansiaux, A; Ryckebusch, A; Schifano-Faux, N | 1 |
| Chen, X; Lin, X; Skolnik, S; Wang, J | 1 |
| Ahn, G; Baldeyrou, B; Couture, A; Goossens, JF; Grandclaudon, P; Lansiaux, A; Ryckebusch, A; Schifano-Faux, N | 1 |
| Godlewska, J; Kaczmarek, L; Luniewski, W; Peczynska-Czoch, W; Piskozub, M; Switalska, M; Wietrzyk, J | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Fisher, GR; Gutierrez, PL; Oldcorne, MA; Patterson, LH | 1 |
| Borowski, E; Garnier-Suillerot, A; Stefańska, B; Tarasiuk, J | 1 |
| Sumner, AT | 1 |
| Glisson, BS; Killary, AM; Merta, P; Ross, WE; Siciliano, J; Siciliano, MJ | 1 |
| Damiani, D; Dinota, A; Fanin, R; Geromin, A; Michelutti, A; Michieli, M; Pileri, S; Raspadori, D; Russo, D; Visani, G | 1 |
| Delmer, A; Helou, C; Marie, JP; Thevenin, D; Zittoun, R | 1 |
| Legrand, O; Marie, JP; Russo, D; Suberville, AM; Zhou, D; Zittoun, R | 1 |
| Chiba, S; Hanazono, Y; Hirai, H; Miura, Y; Miyagawa, K; Miyazono, K; Piao, YF; Sakamoto, S; Taketazu, F; Yazaki, Y | 1 |
| Braunsteiner, H; Dietze, O; Herold, M; Nachbaur, K; Thaler, J; Vogel, W | 1 |
| Belin, T; Champlin, R; Gajewski, J; Lee, M; Nimer, S; Schiller, G; Territo, M | 1 |
| Akiyoshi, T; Hisano, S; Ishibashi, M; Kimura, N; Morioka, E; Okumura, M; Suzumiya, J; Uchida, T | 1 |
| Kimura, F; Mizukami, H; Motoyoshi, K; Nagata, N; Ohtsuki, T; Takagi, S; Takemura, Y; Yamamoto, K | 1 |
| Besterman, JM; George, JW; Ghate, S; Matson, SW | 1 |
| Berman, E | 1 |
| Resegotti, L | 1 |
| Bisserbe, S; Marie, JP; Wdowik, T; Zittoun, R | 1 |
| Gray, RG; Rees, JK | 1 |
| Wiernik, PH | 1 |
| Ito, T; Ito, Y; Kitaori, K; Nagai, T; Ohno, R; Okumura, M; Sugiura, I; Takeo, T; Yano, K; Yokomaku, S | 1 |
| Boeckmann, A; Freire, EA; Frisch, J; Hiddemann, W; Innig, G; Reuter, C; Rottmann, R; Schulz, G; Wörmann, B; Zühlsdorf, M | 1 |
| Bastida Vila, P; Giralt López, J; Javier Manchón, G; Olivé Oliveras, T; Ortega Aramburu, JJ; Sánchez, C | 1 |
| Boeckmann, A; Büchner, T; Freire, EA; Hiddemann, W; Innig, G; Koenigsmann, M; Ludwig, WD; Maschmeyer, G; Wörmann, B; Zühlsdorf, M | 1 |
| Andreoni, A; Colasanti, A; Malatesta, V; Riccio, P; Roberti, G | 1 |
| Hedenus, M; Hörnsten, P; Malm, C; Wahlin, A | 1 |
| Granada, I; Las Heras, G; Millá, F; Ribera, JM | 1 |
| Farhi, DC; Rosenthal, NS | 1 |
| Barzi, A; Lepri, E; Liberati, M; Menconi, E; Portuese, MG; Santucci, A | 1 |
| Budman, DR; Cuttner, J; Davey, F; Henderson, ES; Lee, EJ; Mayer, RJ; Mick, R; Paciucci, PA; Sobol, R; Weiss, RB | 1 |
| Potter, MN; Rogers, S; Slade, RR | 1 |
| Borowski, E; Kolodziejczyk, P; Tarasiuk, J | 1 |
| Arlin, Z; Cartwright, K; Case, DC; Desai, P; Feldman, E; Moore, J; Saletan, S; Sia, L; Wiernik, P | 1 |
| Appelt, M; Büchner, T; Eichelbaum, M; Grille, W; Hiddemann, W; Hossfeld, DK; Koslowski, B; Kraft, J; Kuse, R; Quabeck, K | 1 |
| Aul, HC; Donhuijsen-Ant, R; Grüneisen, T; Hiddemann, W; Köppler, H; Lathan, B; Ludwig, WD; Maschmeyer, G; Reichle, A; Urbanitz, D | 1 |
| Büchner, T; Hagemeister, B; Hiddemann, W; Kusnierz-Glaz, C; Reiser, M; van de Loo, J | 1 |
| Kühn, B; Löffler, H; Polchau, H; Rister, M; Suttorp, M | 1 |
| Büchner, T; Essink, ME; Hiddemann, W; van de Loo, J; von Eiff, M | 1 |
| Conway, BR; Ellis, AL; Gewirtz, DA; Randolph, JK | 1 |
| Cunningham, M | 1 |
| Bosanquet, AG | 1 |
| Arkin, H; Holland, JF; Ohnuma, T | 1 |
| Cole, SP; Gerlach, JH; Mirski, SE | 1 |
| Chan, HS; Estrov, Z; Freedman, MH; Weitzman, SS | 1 |
| Vile, GF; Winterbourn, CC | 1 |
| Demant, EJ; Hansen, HH; Jensen, PB; Roed, H; Sehested, M; Skovsgaard, T; Vindeløv, L | 1 |
| Hamada, H; Ishida, Y; Minato, K; Ohtsu, T; Shimoyama, M; Sugimoto, Y; Tobinai, K; Tsuruo, T | 1 |
| Kyo, T; Maehama, S | 1 |
| Stevens, RF; Wilkins, KM | 1 |
| Arlin, ZA | 1 |
| Ganapathi, R; Grabowski, D; Israel, M; Schmidt, H; Seshadri, R | 1 |
| Raymond, V; Young, CW | 1 |
| Capizzi, RL; Chandrasekaran, B; Dimling, J | 1 |
| Carmichael, AJ; Riesz, P | 1 |
| Kharasch, ED; Novak, RF | 3 |
| Davies, KJ; Doroshow, JH | 1 |
| de Vries, EG; Le, TK; Meijer, C; Mulder, NH; Timmer-Bosscha, H; Zijlstra, JG | 1 |
| Estey, E; Freireich, EJ; Kantarjian, HM; Keating, MJ; McCredie, KB; Smith, T; Walters, R | 1 |
| Falkson, G; Iturralde, MP; Vorobiof, DA | 1 |
| Gorin, NC; Isnard, F; Laporte, JP; Lemonnier, MP; Najman, A | 1 |
| Abramson, JJ; Buck, E; Casida, JE; Pessah, IN; Salama, G | 1 |
| Büchner, T; Gassmann, W; Hiddemann, W; Kreutzmann, H; Kuse, R; Löffler, H; Maschmeyer, G; Mohr, A; Urbanitz, D; Wendt, F | 1 |
| Amadori, S; Avvisati, G; Mandelli, F; Meloni, G; Petti, MC; Tafuri, A | 1 |
| Kimura, I; Kitani, T; Masaoka, T; Meguro, S; Nagai, K; Ogawa, M; Ohnoshi, T; Sampi, K; Wakui, A; Yamada, K | 1 |
| Löwenberg, B; Schölzel, C; van Putten, W | 1 |
| Bachur, NR; Bernstein, AL; Dodion, P; Fox, BM | 1 |
| Arlin, Z; Büchner, T; Donhuijsen-Ant, R; Hiddemann, W; Kreutzmann, H; Lengfelder, E; Ludwig, WD; Mertelsmann, R; Straif, K | 1 |
| Arlin, Z; Büchner, T; Donhuijsen-Ant, R; Hiddemann, W; Kreutzmann, H; Lengfelder, E; Ludwig, WD; Mertelsmann, R; Planker, M; Straif, K | 1 |
| Bauch, HJ; Pielken, HJ; Preusser, P | 1 |
| Krishnamoorthy, CR; Lown, JW; Smith, JC; Wilson, WD; Yen, SF | 1 |
| Horiuchi, A; Kawagoe, H; Kitani, T; Masaoka, T; Nagai, K; Oguma, S; Shibata, H; Yasunaga, K; Yonezawa, T | 1 |
| Ogawa, M | 1 |
| Hanck, KW; Motten, AG; Sinha, BK | 1 |
| Akao, Y; Sao, H; Tahara, T; Yoshikawa, H; Yoshikawa, S | 1 |
| Himori, T; Ohnuma, T; Wakui, A | 1 |
| Brown, JR; Gandecha, BM; Patterson, LH | 1 |
| Holland, JF; Richardson, CL; Roboz, J | 1 |
| Feldmann, L; Guerci, A; Guerci, O; Marchal, S; Merlin, JL; Missoum, N; Rose, C; Witz, F | 1 |
| Aster, JC; Inhorn, RC; Roach, SA; Slapak, CA; Soiffer, R; Stone, RM; Tantravahi, R | 1 |
| Abe, T; Hirao, A; Kawano, Y; Okamoto, Y; Saito, S; Sato, J; Shimizu, T; Suzue, T; Takaue, Y; Watanabe, T | 1 |
| Bergmann, L; Hoelzer, D; Jacobi, V; Lob, S; Müller, H | 1 |
| Calvert, L; Claxton, D; Durett, A; Giralt, S; Hamer, J; Kantarjian, H; Khouri, I; Liang, J; Talpaz, M; Tibbits, P | 1 |
| den Boer, ML; Huismans, DR; Klumper, E; Loonen, AH; Pieters, R; Veerman, AJ | 1 |
| Archim-Baud, E; Castaigne, S; Chastang, C; Chomienne, C; Degos, L; Fenaux, P; Fey, M; Link, H; Löwenberg, B; Sanz, M | 1 |
| Kule, C; Ondrejickova, O; Verner, K | 1 |
| Champlin, R; Gajewski, J; Ho, W; Lee, M; Schiller, G; Territo, M | 1 |
| Aul, C; Bartram, CR; Heyll, A; Hildebrandt, B; Ludwig, WD; Meckenstock, G; Runde, V; Schneider, EM; Schneider, W | 1 |
| Cianfriglia, M; Eisterer, W; Gotwald, M; Hilbe, W; Hofmann, J; Ludescher, C; Thaler, J; Zabernigg, A | 1 |
| Calvert, L; Deisseroth, AB; Feldman, E; Hester, J; Kantarjian, HM; Korbling, M; Liang, J; Rios, MB; Smith, TL; Talpaz, M | 1 |
| Altenberg, GA; Belli, JA; Eberle, RL; Sognier, MA; Sweet, KM; Zhang, Y | 1 |
| Fridborg, H; Killander, A; Kristensen, J; Larsson, R; Liliemark, J; Nygren, P; Oberg, G; Simonsson, B | 1 |
| Eppinger-Helft, M; Fernandez, I; Garcia Martinez, MA; Gonzalez Llaven, J; Ibarra, S; López-Hernández, M; Marin, A; Pavlovsky, S; Rubio, ME; Sobrevilla, P | 1 |
| Damon, LE; Linker, CA; Ries, CA; Rugo, HS | 1 |
| Batlle, J; López Fernández, MF; Rodríguez Gómez, M | 1 |
| Kaletin, GI; Pirogova, NA; Volkova, MA | 1 |
| Perilov, AA; Poddubnaia, IV | 1 |
| de Waal, FC; Hählen, K; Kaspers, GL; Klumper, E; Pieters, R; van Wering, ER; van Zantwijk, I; Veerman, AJ | 1 |
| Dorn, A; Graf, N; Pees, HW | 1 |
| Abe, Y; Hatanaka, T; Ito, T; Kamiya, O; Nagata, K; Ohara, K; Ono, Y; Saito, M | 1 |
| Kobayashi, K; Kyohda, K; Matano, S; Matsuda, T; Nakamura, S; Ohtake, S; Okabe, Y; Okumura, H; Yoshida, T | 1 |
| Chen, LM; Huang, SH; Hwang, WS; Tseng, MT; Wang, CC | 1 |
| Delmer, A; Marie, JP; Suberville, AM; Thevenin, D; Zittoun, R | 1 |
| Gondo, H; Harada, M; Matsuishi, H; Omori, F; Otsuka, T; Shibuya, T; Taniguchi, S; Teshima, T; Yamano, Y; Yamazaki, K | 1 |
| Becher, R; Fonatsch, C; Gassmann, W; Haase, D; Haferlach, T; Jürgensen, C; Löffler, H; Ludwig, WD; Noak, J; Thiel, E | 1 |
| Hirakawa, K; Horiike, S; Kaneko, H; Kashima, K; Misawa, S; Nakai, H; Nakao, M; Taniwaki, M; Ueda, Y | 1 |
| Groenewegen, A; Löwenberg, B; Sonneveld, P; Vellenga, E; Wielenga, JJ | 1 |
| Bow, EJ; Cheang, MS; Loewen, R; Schacter, B | 1 |
| Dann, EJ; Gillis, S; Rund, D | 1 |
| Elonen, E; Jokipii, A; Lautenschlager, I; Lyytikäinen, O; Ruutu, P; Tiittanen, L | 1 |
| Fey, MF; Hardegger, TP; Tobler, A; von Rohr, A | 1 |
| Ezaki, K; Hirano, M; Ino, T; Miyazaki, H; Okamoto, M; Tsuzuki, M | 1 |
| Clausen, N; Hokland, P; Langkjer, ST; Nørgaard, JM; Palshof, T; Pedersen, B | 1 |
| Huismans, DR; Klumper, E; Loonen, AH; Ossenkoppele, GJ; Pieters, R; Rottier, A; Veerman, AJ; Westra, G | 1 |
| Chong, SY; Hahn, JS; Ko, YW; Lee, JW; Lee, S; Min, YH | 1 |
| Appelbaum, FR; Bensinger, WI; Buckner, CD; Chauncey, T; Demirer, T; Fefer, A; Lilleby, K; Petersen, FB; Rowley, S; Sanders, J; Storb, R | 1 |
| Fukushima, T; Imamura, S; Kamiya, K; Kawai, Y; Nakamura, T; Nakayama, T; Tsutani, H; Ueda, T; Urasaki, Y; Yamauchi, T; Yoshida, A | 1 |
| Chim, CS; Kwong, YL | 1 |
| Gonzalez-Gonzalez, A; Pinilla, J; Requena, A; Velasco, JG | 1 |
| Ezaki, K; Hirano, M; Ino, T; Kojima, H; Maruyama, F; Matsui, T; Miyazaki, H; Nomura, T; Okamoto, M; Tsuzuki, M; Wakita, M; Yamaguchi, T | 1 |
| Bailly, C; Minnock, A; Waring, MJ | 1 |
| Archimbaud, E; Auzanneau, G; Cony-Makhoul, P; Cordonnier, C; Dombret, H; Dreyfus, F; Fenaux, P; Ffrench, M; Leblond, V; Marie, JP; Thomas, X; Tilly, H; Troussard, X | 1 |
| Flexner, JM; Goodman, S; Greer, JP; Stein, RS; Wolff, SN | 1 |
| Ando, T; Ariyoshi, K; Hikiji, K; Kobayashi, M; Shinohara, K; Toyosawa, M | 1 |
| Horikawa, K; Okada, Y; Sano, M | 1 |
| Ezaki, K; Hirano, M; Ino, T; Kojima, H; Maruyama, F; Matsui, T; Miyazaki, H; Nomura, T; Okamoto, M; Tsuzuki, M; Yamaguchi, T | 1 |
| Hanada, R; Hongo, T; Horikoshi, Y; Sakurai, M; Yajima, S | 1 |
| Belloc, F; Bernard, P; Besnard, S; Boisseau, MR; Dumain, P; Lacombe, F; Reiffers, J; Vial, JP | 1 |
| Brodsky, AL; Melero, MJ; Minissale, CJ; Sánchez Avalos, JC | 1 |
| Asschert, J; de Vries, E; Müller, M; van der Kolk, D; Vellenga, E | 1 |
| Ohnishi, K; Ohno, R; Shinjyo, K; Takeshita, A; Tobita, T; Yanagi, M | 1 |
| Borg, AG; Burgess, R; Fisher, A; Grey, M; Wood, P; Yin, JA | 1 |
| Cuttner, J; Davis, RB; Gottlieb, A; Holland, JF; Martelo, O; Paciucci, PA | 1 |
| Akashi, K; Eto, T; Fujisaki, T; Gondo, H; Harada, M; Harada, N; Hayashi, S; Hirota, Y; Kinukawa, N; Makino, S; Matsuishi, E; Miyamoto, T; Mizuno, S; Murakawa, M; Nagafuji, K; Niho, Y; Ohno, Y; Okamura, T; Shibuya, T; Takamatsu, Y; Takenaka, K; Taniguchi, S; Tanimoto, K; Teshima, T; Yamasaki, K | 1 |
| Bukh, A; Clausen, N; Hokland, P; Langkjer, ST; Nørgaard, JM; Palshof, T | 1 |
| Archimbaud, E; Berneman, ZN; de Cataldo, R; Dekker, AW; Fillet, G; Haak, H; Hagemeijer, A; Hayat, M; Löwenberg, B; Solbu, G; Sonneveld, P; Stryckmans, P; Suciu, S; Thyss, A; van der Lelie, J; Visani, G; Zittoun, R | 1 |
| Büchner, T; Kessler, T; Schumacher, A; van de Loo, J; Wewers, D | 1 |
| Gray, RG; Hann, IM; Stevens, RF; Wheatley, K | 1 |
| Bender-Götze, C; Creutzig, U; Körholz, D; Niemeyer, C; Ritter, J; Stollmann-Gibbels, B; Zimmermann, M | 1 |
| Lemez, P; Maresová, J | 1 |
| Bernasconi, C; Castagnola, C; Corso, A; Dabusti, M; Lazzarino, M; Lunghi, M; Tajana, M; Zappasodi, P | 1 |
| Baak, JP; Broxterman, HJ; Eekman, CA; Feller, N; Klumper, E; Kuiper, CM; Ossenkoppele, GJ; Pieters, R; Schuurhuis, GJ; van Heijningen, TH | 1 |
| Akan, H; Arat, M; Arslan, O; Beksaç, M; Gürman, G; Ilhan, O; Koç, H; Konuk, N; Ozcan, M; Uysal, A | 1 |
| De La Rubia, J; Gomis, F; González-García, Y; Jarque, I; Martín, G; Pérez-Sirvent, M; Sanz, MA; Sempere, A; Senent, L | 1 |
| Feliu, E; Hernández, JA; Millá, F; Navarro, JT; Oriol, A; Pujol, M; Ribera, JM; Sancho, JM | 1 |
| Dietel, M; Hütter, G; Köttgen, E; Lage, H; Schadendorf, D; Sinha, P | 1 |
| Bettaïeb, A; Jaffrézou, JP; Laurent, G; Levade, T; Mansat-De Mas, V; Plo, I; Quillet-Mary, A | 1 |
| Aguado, MJ; Arrieta, R; Bustos, JG; Canales, MA; Hernández-García, C; Hernández-Navarro, F | 1 |
| Diehl, V; Engert, A; Hegener, K; Hübel, K; Mansmann, G; Oberhäuser, F; Schnell, R; Staib, P | 1 |
| Aul, C; Büchner, T; Fonatsch, C; Gassmann, W; Haase, D; Haferlach, T; Heinecke, A; Heyll, A; Hiddemann, W; Hossfeld, D; Lengfelder, E; Löffler, H; Ludwig, WD; Maschmeyer, G; Sauerland, MC; Schoch, C; Wörmann, B | 1 |
| Ehninger, G; Illmer, T; Neubauer, A; Nowak, R; Oelschlägel, U; Renner, U; Schaich, M; Subat, S; Ziegs, B | 1 |
| Andreesen, R; Meidenbauer, N; Obermann, E; Reichle, A; Zeltner, R | 1 |
| Ghosh, K; Hiwase, D; Mitra, S | 1 |
| Fujii, S; Fukushi, Y; Futagami, M; Higuchi, T; Saito, Y; Sakamoto, T; Sato, S; Takami, H; Yokoyama, Y | 1 |
| Ezaki, K; Hasegawa, A; Hirano, M; Ino, T; Kojima, H; Maruyama, F; Matsui, T; Miyazaki, H; Okamoto, M; Tsuzuki, M | 1 |
| Eriksen, J; Friche, E; Kjaersgaard, E; Litman, T; Maare, C; Nielsen, D; Plesner, T; Skovsgaard, T | 1 |
| Bian, S; Luo, M; Xue, Y | 1 |
| Huismans, DR; Pieters, R; Schuurhuis, GJ; Styczynski, J; Veerman, AJ; Wysocki, M | 1 |
| Aivado, M; Aul, C; Gattermann, N; Germing, U; Haas, R; Kobbe, G; Rieth, C; Rong, A | 1 |
| Büchner, T; Fonatsch, C; Haase, D; Haferlach, T; Heinecke, A; Hiddemann, W; Löffler, H; Sauerland, MC; Schlegelberger, B; Schoch, C; Staib, P | 1 |
| Buckley, DA; du Vivier, AW; Hopster, D; Keane, FM; Mufti, GJ; Munn, SE | 1 |
| Cabrera, ME; Ducach, G; Etcheverry, R; Puga, BL; Toledo, H; Undurraga, MS; Vacarezza, R | 1 |
| Hokland, P; Langkjer, ST; Nørgaard, JM; Palshof, T; Pedersen, B | 1 |
| Berthold, F; Creutzig, U; Gadner, H; Havers, W; Henze, G; Hermann, J; Jürgens, H; Kabisch, H; Kluba, U; Niggli, F; Reinhardt, D; Reiter, A; Ritter, J; Zimmermann, M | 1 |
| Fletcher, BD; Harrison, PL; Kaste, SC; Kennedy, W; Neel, MD; Pui, CH; Razzouk, BI; Relling, MV; Ribeiro, RC; Rubnitz, JE; Sandlund, JT | 1 |
| Bernasconi, P; Boni, M; Castoldi, GL; Ciolli, S; Clavio, M; Cox, MC; Cuneo, A; Del Poeta, G; Dini, D; Falzetti, D; Fanin, R; Gobbi, M; Isidori, A; Leoni, F; Liso, V; Malagola, M; Mandelli, F; Martinelli, G; Mecucci, C; Petti, MC; Piccaluga, PP; Rondelli, R; Russo, D; Sessarego, M; Specchia, G; Testoni, N; Torelli, G; Tura, S; Visani, G | 1 |
| Glimelius, B; Kimby, E; Nygren, P | 1 |
| Andreeff, M; Brenner, MK; Goodell, MA; Kuehnle, I; Marini, F; Wang, RY; Weidner, D; Wulf, GG | 1 |
| Burnett, AK; Clark, RE; Goldstone, AH; Hutchinson, RM; Smith, AG; Wheatley, K | 1 |
| Budman, DR; Calabro, A; Kreis, W | 1 |
| Chen, Y; Pant, AC; Rajagopal, A; Simon, SM | 1 |
| Appelbaum, FR | 1 |
| Dan, K; Inami, M; Inokuchi, K; Miyata, J; Tajika, K; Watanabe, A; Yamaguchi, H; Yokomizo, E | 1 |
| Bendix, K; Hokland, P; Kjeldsen, E; Kristensen, JS; Meyer, K; Nørgaard, JM; Olesen, G; Olesen, LH; Pedersen, B | 1 |
| Kowalski, P; Lage, H; Scheffer, GL; Stein, U | 1 |
| Dietel, M; Lage, H | 1 |
| Gaidarova, S; Jiménez, SA | 1 |
| Handa, H; Isozumi, K; Komatsumoto, S; Motohashi, S; Nara, M | 1 |
| Anderson, JE; Appelbaum, FR; Balcerzak, SP; Chen, IM; Head, D; Johnson, DB; Kopecky, KJ; Luthardt, FW; Norwood, TH; O'Donnell, MR; Willman, CL | 1 |
| Borker, A; Ode, D; Yu, L | 1 |
| Andersson, PO; Brune, M; Gustavsson, B; Stockelberg, D; Wadenvik, H; Wernstedt, P | 1 |
| Lage, H; Poland, J; Sinha, P; Tönnies, H | 1 |
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| Diehl, V; Glossmann, JP; Josting, A; Staak, JO; Wickenhauser, C | 1 |
| Herrmann, A; Lage, H; Osada, H; Woehlecke, H | 1 |
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| Graf, M; Hecht, K; Nuessler, V; Pelka-Fleischer, R; Pfister, K; Reif, S; Schmetzer, H | 1 |
| Júźwiak, Z; Krykowski, E; Marczak, A; Robak, T; Wrzesień-Kuś, A | 1 |
| Aul, C; Berdel, WE; Büchner, T; Fonatsch, C; Frickhofen, N; Gruneisen, A; Haferlach, T; Heinecke, A; Hiddemann, W; Kern, W; Lengfelder, E; Löffler, H; Ludwig, WD; Maschmeyer, G; Mesters, RM; Sauerland, MC; Schoch, C; Serve, HL; Staib, P; Wörmann, B | 1 |
| Babu, K; Bhattacharjee, H; Bhattacharjee, K; Biswas, J; Das, D; Krishnakumar, S; Mahesh, L | 1 |
| Kondo, T; Mikami, M; Nakanishi, H; Otsuki, T; Suemori, S; Suetsugu, Y; Sugihara, T; Tsujioka, T; Wada, H; Yamamori, S | 1 |
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| Haferlach, T; Hiddemann, W; Kern, W; Schnittger, S; Schoch, C; Voskova, D | 1 |
| Berdel, WE; Büchner, T; Hiddemann, W | 1 |
| Chiam, AS; Huxham, LA; Kyle, AH; Minchinton, AI; Sim, DH | 1 |
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| Kalaycio, M | 1 |
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| Czyz, A; Gwizdek-Wiśniewska, A; Ochociński, J; Piosik, J; Ulanowska, K; Wegrzyn, G | 1 |
| Abdul-Ghani, R; Dietel, M; Garber, M; Györffy, B; Jürchott, K; Lage, H; Petersen, I; Schäfer, R; Serra, V; Stein, U | 1 |
| Bloomfield, CD; Carroll, AJ; Edwards, CG; Kolitz, JE; Larson, RA; Maharry, K; Marcucci, G; Mayer, RJ; Moore, JO; Mrózek, K; Pettenati, MJ; Powell, BL; Ruppert, AS; Schiffer, CA; Sterling, LJ; Vardiman, JW | 1 |
| Lemez, P; Urbánek, V | 1 |
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| de Graaf, SS; Gibson, BE; Hann, IM; Hills, RK; O'Marcaigh, A; Rao, A; Stiller, C; Webb, DK; Wheatley, K | 1 |
| Aung, L; Kirk, RC; Liang, S; Quah, TC; Tan, RM; Yeoh, AE | 1 |
| Ishikawa, T; Kamachi, T; Nakagawa, H; Okura, I; Saito, H; Tamura, A; Watanabe, M | 1 |
| Campbell, KJ; O'Shea, JM; Perkins, ND | 1 |
| Jekerle, V; Klinkhammer, W; Piquette-Miller, M; Reilly, RM; Wiese, M | 1 |
| Cheng, JH; Liu, F; Wu, YH; Zhang, M; Zou, P | 1 |
| Breitbach, K; Jekerle, V; Klinkhammer, W; Piquette-Miller, M; Reilly, RM; Scollard, DA; Wiese, M | 1 |
| Do, DV; Han, HC; Khoo, YT; Lim, IJ; Mukhopadhyay, A; Ong, CT; Phan, TT | 1 |
| Braess, J; Haferlach, T; Holdenrieder, S; Mueller, S; Nagel, D; Schalhorn, A; Seidel, D; Stieber, P | 1 |
| Salonen, JH | 1 |
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| Martin, PL; McLean, TW; White, MS | 1 |
| Do, DV; Han, HC; Khoo, YT; Lim, IJ; Mukhopadhyay, A; Ong, CT; Phan, TT; Tan, EK | 1 |
| Arnaud, P; Botton, Sd; Bourhis, JH; Castaigne, S; Cordonnier, C; Corront, B; de Revel, T; Dombret, H; Elhamri, M; Fenaux, P; Gardin, C; Le, QH; Michallet, M; Pautas, C; Preudhomme, C; Quesnel, B; Raffoux, E; Reman, O; Terré, C; Thomas, X | 1 |
| Chen, H; Han, W; Huang, XJ; Liu, DH; Liu, KY; Xu, LP | 1 |
| Haferlach, C; Hiddemann, W; Schnittger, S; Weisser, M | 1 |
| Amadori, S; Buccisano, F; Consalvo, MI; De Fabritiis, P; Del Poeta, G; Del Principe, MI; Fraboni, D; Maurillo, L; Mazzone, C; Neri, B; Ottaviani, L; Panetta, P; Sarlo, C; Spagnoli, A; Tamburini, A; Venditti, A | 1 |
| Davies, DB; Evstigneev, MP; Kostjukov, VV; Lantushenko, AO | 1 |
| Fujiwara, M; Higashimura, M; Izumi, N; Koike, T; Satou, N; Shibasaki, Y; Tsukada, N | 1 |
| Becton, D; Chang, MN; Dahl, GV; Massey, GV; O'Brien, MM; Raimondi, SC; Ravindranath, Y; Stine, KC; Taub, JW | 1 |
| Bian, S; Liu, S; Meng, Q; Mi, Y; Wang, J; Xue, Y; Yu, W; Zhao, Y | 1 |
| Kurahashi, S; Narimatsu, H; Sugimoto, T; Sugiura, I; Yamamoto, F | 1 |
| Comijn, EM; Hubeek, I; Kaspers, GJ; Merriman, RL; Padron, JM; Peters, GJ; Van der Wilt, CL | 1 |
| Beverloo, HB; Cornelissen, JJ; Deenik, W; Valk, PJ; van der Poel-van de Luytgaarde, SC; van Esser, JW; Wattel, MM | 1 |
| Karp, J | 1 |
| Horacek, JM; Jakl, M; Jebavy, L; Pudil, R | 1 |
| Li, Y; Mi, Y; Qiu, L; Wang, J; Zhao, Y; Zou, D | 1 |
| Darzynkiewicz, Z; Halicka, HD; Jayabose, S; Kajstura, M; Levendoglu-Tugal, O; Ozkaynak, MF; Sandoval, C; Seiter, K; Traganos, F | 1 |
| Betancourt-García, RD; Castro, J; Fernández, AC; Fradera, J; López-Enríquez, A; Pacheco, E | 1 |
| Hu, NP; Hu, XM; Li, L; Liu, C; Liu, F; Ma, R; Wang, HZ; Xiao, HY; Xu, YG; Yang, XH; Zhang, SS; Zheng, CM | 1 |
| de Bont, ES; Kamps, WA; Koetse, HA; Rings, EH; Stellaard, F; Tissing, WJ; van Vliet, MJ | 1 |
| Amadori, S; Baila, L; de Witte, T; Di Raimondo, F; Fazi, P; Ferrara, F; Labar, B; Liso, V; Mandelli, F; Marie, JP; Marmont, F; Meloni, G; Muus, P; Petti, MC; Stasi, R; Suciu, S; Thomas, X; Vignetti, M; Willemze, R; Zittoun, R | 1 |
| Akutsu, M; Furukawa, Y; Izumi, T; Kano, Y; Mano, H; Miyawaki, S; Tanaka, M; Tsunoda, S; Yazawa, Y | 1 |
| Burnett, AK; Duncombe, A; Gibson, B; Goldstone, AH; Hills, RK; McMullin, MF; Milligan, DW; Prentice, AG; Wheatley, K | 1 |
| Dessalvi, P; Di Tucci, AA; Emanuele, A; Pettinau, M; Romani, C | 1 |
| Dvoráková, D; Gáliková, J; Lemez, P; MacWhannell, A; Michalová, K; Stejskal, J; Zemanová, Z | 1 |
| Bubanska, E; Hrebik, M; Mladosievicova, B; Urbanova, D | 1 |
| Briel, J; Gocke, CD; Hess, AD; Kanakry, CG; Karp, JE; Kos, F; Levitsky, H; Luznik, L; Meyer, C; Smith, BD; Thoburn, C | 1 |
| Berdel, WE; Braess, J; Büchner, T; Ehninger, G; Haferlach, C; Haferlach, T; Heinecke, A; Hiddemann, W; Koschmieder, A; Koschmieder, S; Kramer, M; Krug, U; Müller-Tidow, C; Rohde, C; Röllig, C; Sauerland, MC; Schaich, M; Serve, H; Spiekermann, K; Thiede, C; Wörmann, B | 1 |
| Pham, XH; Tran, NQ; Tuteja, N; Tuteja, R | 1 |
| Czarnik-Matusewicz, H; Ganczarski, G; Gąsiorowski, J; Głowacka, K; Kuliczkowski, K; Orzechowska-Juzwenko, K; Wiela-Hojeńska, A; Wołowiec, D; Łapiński, Ł | 1 |
| Barbier, P; Bourgarel-Rey, V; Boutonnat, J; Combes, S; Douillard, S; Fedorov, AY; Finet, JP; McLeer-Florin, A; Peyrot, V; Pierson, JT | 1 |
| Che, S; Xing, L; Zheng, H | 1 |
| Belinka, BA; Gupta, A; Kachlany, SC; Le, A | 1 |
| Beck, WT; Bleeker, NP; Das, SG; Doshi, JM; Hermanson, DL; Srinivasan, B; Tang, R; Xing, C | 1 |
| De Graaf, SS; Gibson, BE; Harrison, CJ; Howman, AJ; Webb, DK; Wheatley, K | 1 |
| Abe, M; Amou, H; Cui, Q; El Sayed, SM; Fujii, S; Harada, T; Ikegame, A; Itoh, K; Kagawa, K; Matsumoto, T; Miki, H; Nakamura, S; Nakamura, T; Nakano, A; Oda, A; Okano, K; Ozaki, S; Sakai, A; Takeuchi, K; Tsuji, D | 1 |
| Atenafu, EG; Brandwein, JM; Gupta, V; Minden, MD; Murray, C; Nixon, S; Saini, L; Schimmer, AD; Schuh, AC; Yee, KW | 1 |
| Burnett, AK | 1 |
| Qiu, HY; Sun, AN; Wang, WJ | 1 |
| Berkowitz, J; Bernard, L; Hogge, DE; Kim, HP; Nitta, J | 1 |
| Appelbaum, FR; Geraghty, DE; Godwin, JE; Ho, PA; Kutny, M; Meshinchi, S; Ostronoff, F; Othus, M; Petersdorf, SH; Radich, JP; Stirewalt, DL; Willman, CL | 1 |
| Aul, C; Berdel, WE; Braess, J; Büchner, T; Erben, P; Haferlach, C; Haferlach, T; Hanfstein, B; Hehlmann, R; Heinecke, A; Hiddemann, W; Hofmann, WK; Horst, HA; Kreuzer, KA; Krug, U; Lengfelder, E; Müller-Tidow, C; Sauerland, C; Schneider, S; Schnittger, S; Schultheis, B; Serve, H; Spiekermann, K; Wörmann, B | 1 |
| Chen, H; Liu, J; Liu, L; Liu, M; Shi, B; Ye, L; Yu, L; Zhang, Y | 1 |
| Atenafu, EG; Brandwein, JM; Gupta, V; Hassanein, M; Minden, MD; Schimmer, AD; Schuh, AC; Yee, KW | 1 |
| Chen, H; Hu, J; Hu, L; Jiang, M; Li, B; Li, Y; Lou, X; Ning, H; Wang, J; Xu, C; Yu, Z | 1 |
| Aulitzky, W; Baldus, CD; Berdel, WE; Bornhäuser, M; Ehninger, G; Einsele, H; Hänel, M; Ho, AD; Illmer, T; Kramer, M; Krause, SW; Mayer, J; Neubauer, A; Parmentier, S; Röllig, C; Schäfer-Eckart, K; Schaich, M; Schetelig, J; Schmitz, N; Serve, H; Stölzel, F; Thiede, C | 1 |
| Cho, BS; Cho, SG; Eom, KS; Kim, DW; Kim, HJ; Kim, JH; Kim, YJ; Lee, JW; Lee, S; Lee, SE; Min, CK; Min, WS; Park, CW; Shin, SH; Yahng, SA; Yoon, JH | 1 |
| Beyer, F; Franke, M; Persigehl, T; Theurich, S | 1 |
| Bergsagel, J; Cooper, T; Daves, M; Keller, F; Lew, G; Nickel, RS; Sabnis, H | 1 |
| Chung, NG; Jang, W; Kim, M; Lee, JW | 1 |
| Deng, Z; Ding, B; Li, Y; Shi, Y; Zho, J | 1 |
| Batár, P; Bedekovics, J; Hevessy, Z; Illés, A; Kiss, A; Márton, A; Pinczés, L; Rejtő, L; Reményi, G; Selmeczi, A; Szász, R; Telek, B; Udvardy, M; Ujfalusi, A; Ujj, Z | 1 |
| Iacoboni, G; Montesinos, P; Sanz, MA | 1 |
| Cortes, JE; Feldman, EJ; Goldberg, SL; Hogge, DE; Kantarjian, H; Kolitz, JE; Larson, M; Louie, AC; Pigneux, A; Recher, C; Rizzeri, DA; Schiller, G; Warzocha, K | 1 |
| Berdel, WE; Braess, J; Buechner, T; Greif, PA; Heinecke, A; Hiddemann, W; Krug, U; Ksienzyk, B; Mellert, G; Pastore, F; Sauerland, CM; Schneider, S; Spiekermann, K; Woermann, B; Zellmeier, E | 1 |
| Drokov, MIu; Galstian, GM; Kessel'man, SA; Kliasova, GA; Kulikov, SM; Kuz'mina, LA; Obukhova, TN; Paramonova, EV; Parovichnikova, EN; Savchenko, VG; Sokolov, AN; Troitskaia, VV; Vasil'eva, VA | 1 |
| Blackford, AL; Bose, P; Doyle, LA; Foster, MC; Gocke, CD; Gojo, I; Karp, JE; Lancet, JE; Levy, MY; Little, RF; Litzow, MR; Morris, LE; Rosner, GL; Smith, BD; Strickland, SA; Tibes, R; Wright, JJ; Zeidner, JF | 2 |
| Chen, J; Li, X; Tan, Y; Xu, S | 1 |
| Bremer, S; Chaudhari, U; Ellis, JK; Gaspar, JA; Hengstler, JG; Hescheler, J; Keun, HC; Louisse, J; Nemade, H; Nguemo, F; Sachinidis, A; Spitkovski, D; Srinivasan, SP; Wagh, V | 1 |
| Bochennek, K; Creutzig, U; Gilfert, J; Hassler, A; Lehrnbecher, T; Perner, C; Reinhardt, D; Schöning, S | 1 |
| Atisha-Fregoso, Y; Baños-Peláez, M; Contreras-Yáñez, I; Fragoso-Loyo, H; Jakez-Ocampo, J; Lima, G; Llorente, L; Pascual-Ramos, V | 1 |
| Alexander, TB; Inaba, H; Pounds, S; Pui, CH; Ribeiro, RC; Rubnitz, JE; Triplett, BM; Wang, L | 1 |
| Amiri, AH; Dalir Abdolahinia, E; Elahian, F; Ghamghami, M; Gholamian Dehkordi, N; Mirzaei, SA | 1 |
| Berdel, WE; Bornhäuser, M; Ehninger, G; Einsele, H; Fetscher, S; Gabrecht, M; Hänel, M; Heits, F; Herbst, R; Kaiser, U; Krämer, A; Kramer, M; Krümpelmann, U; Kullmer, J; Link, H; Mantovani-Löffler, L; Mohr, B; Neuhaus, T; Platzbecker, U; Ritter, B; Röllig, C; Schäfer-Eckart, K; Schaich, M; Schetelig, J; Schmitz, N; Schuler, US; Serve, H; Thiede, C | 1 |
| Huang, Y; Liu, DD; Lv, TT; Xu, J; Yuan, GL; Zhou, XF | 1 |
| Alonzo, T; Aplenc, R; Gamis, A; Gerbing, RB; Getz, KD; Ky, B; Leahy, AB; Leger, KJ; Sack, L; Sung, L; Woods, WG | 1 |
| Baskhaeva, GA; Davidiva, JO; Drokov, MY; Dvirnik, VN; Fidarova, ZT; Galtseva, IV; Gavrilina, OA; Kokhno, AV; Kulikov, SM; Kuzmina, LA; Kuznetsova, SA; Lobaova, TI; Loukianova, IA; Obukhova, TN; Parovichnikova, EN; Savchenko, VG; Sokolov, AN; Sudarikov, AB; Troitskaya, VV; Vasilyeva, VA | 1 |
| Ayatollahi, H; Bagheryan, Z; Colagar, AH; Zidanloo, SG | 1 |
| Amin, S; Cabot, MC; Claxton, DF; Conaway, MR; Desai, D; Doi, K; Dunton, W; Feith, DJ; Fox, TE; Kester, M; Liu, X; Loughran, TP; Morad, SAF; Tan, SF; Wang, HG | 1 |
| Cai, B; Deng, L; Ying, S; Zhang, C; Zhou, F | 1 |
| Chavez-Blanco, A; Diaz-Chavez, J; Dominguez-Gomez, G; Duenas-Gonzalez, A; Hua, S; Juarez, M; Lai, D; Perez-Montiel, D; Ponce-Toledo, RI; Schcolnik-Cabrera, A; Torres, N; Tovar, AR; Vargas-Castillo, A | 1 |
| Aali, E; Darzi, S; Elahian, F; Mirzaei, SA; Peymani, A; Pishkhan Dibazar, S; Rahmani, B; Shakeri Chaleshtori, L; Shirian, S | 1 |
| Ahmed, F; Ceckova, M; Hofman, J; Sorf, A; Vagiannis, D | 1 |
| Al-Ali, HK; Aul, C; Balleisen, L; Berdel, WE; Cross, M; Dörken, B; Dreger, P; Eimermacher, H; Florschütz, A; Giagounidis, A; Hähling, D; Hegenbart, U; Hehlmann, R; Heinicke, T; Heyn, S; Hiddemann, W; Hirt, C; Hochhaus, A; Hoffmann, VS; Jentzsch, M; Junghanss, C; Kahl, C; Kiehl, M; Krahl, R; Krämer, A; Krug, U; Lang, T; Lengfelder, E; Maschmeyer, G; Mügge, LO; Müller-Tidow, C; Naumann, R; Niederwieser, D; Oldenkott, B; Opitz, B; Peter, N; Pfirrmann, M; Pönisch, W; Reifenrath, K; Sauerland, C; Sayer, H; Schliemann, C; Scholl, S; Schulze, A; Schütte, W; Schwind, S; Serve, H; Späth, C; Staib, P; Vucinic, V; Wolf, HH; Wörmann, B; Zojer, N | 1 |
23 review(s) available for daunorubicin and mitoxantrone
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
New drugs in acute myelogenous leukemia: a review.
Topics: Amsacrine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Evaluation; Humans; Idarubicin; Isomerism; Leukemia, Myeloid, Acute; Mitoxantrone; Remission Induction; Survival Rate; Tretinoin | 1992 |
New agents in the treatment of acute myeloid leukemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cytarabine; Daunorubicin; Drug Evaluation; Etoposide; Humans; Idarubicin; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Remission Induction; Tretinoin | 1991 |
Nonhematologic toxicities of selected chemotherapeutic agents used in the treatment of adult leukemia.
Topics: Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia; Mitoxantrone; Nursing Assessment | 1990 |
Stability of solutions of antineoplastic agents during preparation and storage for in vitro assays. II. Assay methods, adriamycin and the other antitumour antibiotics.
Topics: Adsorption; Anthraquinones; Antibiotics, Antineoplastic; Biological Assay; Bleomycin; Daunorubicin; Doxorubicin; Drug Packaging; Drug Stability; Freezing; Light; Metals; Methods; Micropore Filters; Mitoxantrone; Solutions | 1986 |
Mitoxantrone and amsacrine: two important agents for the treatment of acute myelogenous leukemia (AML) and acute lymphoblastic leukemia (ALL).
Topics: Amsacrine; Daunorubicin; Drug Evaluation; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction | 1989 |
Clinical assessment of the structure-activity relationship of anthracyclines and related synthetic derivatives.
Topics: Aclarubicin; Anthraquinones; Antibiotics, Antineoplastic; Breast Neoplasms; Carubicin; Cell Survival; Daunorubicin; Doxorubicin; Drug Evaluation; Epirubicin; Heart; Humans; Idarubicin; Leukemia; Menogaril; Mitoxantrone; Naphthacenes; Nogalamycin; Sarcoma; Structure-Activity Relationship | 1986 |
[Current status of clinical results of new antitumor drugs].
Topics: Aminoacridines; Amsacrine; Anthracyclines; Anthraquinones; Antibiotics, Antineoplastic; Antineoplastic Agents; Aziridines; Benzoquinones; Carboplatin; Carubicin; Cisplatin; Daunorubicin; Doxorubicin; Eflornithine; Epirubicin; Humans; Idarubicin; Mitoxantrone; Naphthacenes; Neoplasms; Organoplatinum Compounds; Ornithine; Ribavirin | 1985 |
A syndrome of lymphoblastic lymphoma, eosinophilia, and myeloid hyperplasia/malignancy associated with t(8;13)(p11;q11): description of a distinctive clinicopathologic entity.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Carboplatin; Chromosomes, Human, Pair 13; Chromosomes, Human, Pair 8; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Eosinophilia; Etoposide; Fatal Outcome; Female; Humans; Hydroxyurea; Hyperplasia; Ifosfamide; Leukemia, Myeloid; Lymph Nodes; Male; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Pregnancy; Pregnancy Complications, Neoplastic; Remission Induction; Syndrome; Translocation, Genetic; Vincristine | 1995 |
Treatment of newly diagnosed acute promyelocytic leukemia (APL) by all transretinoic acid (ATRA) combined with chemotherapy: The European experience. European APL Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cell Differentiation; China; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Europe; Humans; Immunologic Factors; Leukemia, Promyelocytic, Acute; Leukocytosis; Life Tables; Middle Aged; Mitoxantrone; New York; Pilot Projects; Remission Induction; Survival Rate; Treatment Outcome; Tretinoin | 1995 |
The prognostic value of cytogenetics is reinforced by the kind of induction/consolidation therapy in influencing the outcome of acute myeloid leukemia--analysis of 848 patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosome Deletion; Chromosome Inversion; Chromosomes, Human; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Hepatomegaly; Humans; Idarubicin; Karyotyping; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Prognosis; Remission Induction; Retrospective Studies; Splenomegaly; Survival Analysis; Translocation, Genetic; Treatment Outcome | 2001 |
A systematic overview of chemotherapy effects in acute myeloid leukaemia.
Topics: Acute Disease; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Humans; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Neoplasms, Second Primary; Prognosis; Prospective Studies; Randomized Controlled Trials as Topic; Retrospective Studies; Treatment Outcome | 2001 |
Philadelphia chromosome-positive acute myeloid leukemia with tetraploidy.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cytarabine; Daunorubicin; Fusion Proteins, bcr-abl; Humans; Karyotyping; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Mercaptopurine; Middle Aged; Mitoxantrone; Polyploidy; Prednisolone; Remission Induction; RNA, Messenger; RNA, Neoplasm | 2002 |
Prognosis of inv(16)/t(16;16) acute myeloid leukemia (AML): a survey of 110 cases from the French AML Intergroup.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Chromosome Inversion; Chromosomes, Human, Pair 16; Clinical Trials as Topic; Cytarabine; Daunorubicin; Disease-Free Survival; Female; France; Humans; Idarubicin; Infant; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Life Tables; Male; Middle Aged; Mitoxantrone; Multicenter Studies as Topic; Prognosis; Randomized Controlled Trials as Topic; Remission Induction; Retrospective Studies; Risk Factors; Survival Analysis; Treatment Outcome | 2003 |
Secondary acute leukemia following mitoxantrone-based high-dose chemotherapy for primary breast cancer patients.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Epirubicin; Female; Humans; Incidence; Leukemia, Myeloid; Leukemia, Myelomonocytic, Acute; Leukemia, Promyelocytic, Acute; Leukemia, Radiation-Induced; Lymphatic Metastasis; Melphalan; Middle Aged; Mitoxantrone; Neoplasms, Second Primary; Paclitaxel; Peripheral Blood Stem Cell Transplantation; Radiotherapy, Adjuvant; Thiotepa; Transplantation Conditioning; Transplantation, Autologous | 2003 |
Toxicity of the topoisomerase II inhibitors.
Topics: Antineoplastic Agents; Cardiovascular Diseases; Daunorubicin; Doxorubicin; Enzyme Inhibitors; Epirubicin; Etoposide; Humans; Idarubicin; Leukemia; Middle Aged; Mitoxantrone; Mucositis; Podophyllotoxin; Teniposide; Topoisomerase II Inhibitors; Vascular Diseases | 2005 |
Acquired acute myelogenous leukemia after therapy for acute promyelocytic leukemia with t(15;17): a case report and review of the literature.
Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 3; Chromosomes, Human, Pair 7; Cytarabine; Daunorubicin; Drug Synergism; Fatal Outcome; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Methotrexate; Mitoxantrone; Monosomy; Neoplasms, Second Primary; Translocation, Genetic; Tretinoin | 2009 |
New induction and postinduction strategies in acute myeloid leukemia.
Topics: Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Gemtuzumab; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Mitoxantrone; Prognosis | 2012 |
[A systematic review of MA versus IA regimen for patients with acute myelogenous leukemia].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Young Adult | 2011 |
Conventional induction and post-remission therapy in APL: have we arrived?
Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Clinical Trials as Topic; Consolidation Chemotherapy; Daunorubicin; Harringtonines; Homoharringtonine; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Maintenance Chemotherapy; Mercaptopurine; Methotrexate; Mitoxantrone; Multicenter Studies as Topic; Oxides; Remission Induction; Tretinoin | 2014 |
The effects of idarubicin versus other anthracyclines for induction therapy of patients with newly diagnosed leukaemia.
Topics: Anthracyclines; Antibiotics, Antineoplastic; Daunorubicin; Doxorubicin; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Mitoxantrone; Randomized Controlled Trials as Topic | 2015 |
Effect of Dose Ratio on Mitoxantrone and Daunorubicin in Acute Myeloid Leukemia: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Randomized Controlled Trials as Topic | 2021 |
65 trial(s) available for daunorubicin and mitoxantrone
| Article | Year |
|---|---|
Treatment of acute nonlymphocytic leukemia by combination of recombinant human granulocyte colony-stimulating factor and cytotoxic agents: a report of six cases.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Cytarabine; Daunorubicin; Drug Evaluation; Drug Resistance; Drug Synergism; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Immunologic Factors; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Mitoxantrone; Recombinant Proteins; Remission Induction | 1992 |
Long-term outcome of high-dose cytarabine-based consolidation chemotherapy for adults with acute myelogenous leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Daunorubicin; Drug Administration Schedule; Etoposide; Female; Follow-Up Studies; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Survival Analysis; Time Factors | 1992 |
Treatment of acute non lymphoid leukemia (ANLL) in elderly patients. The GIMEMA experience.
Topics: Age Factors; Aged; Aged, 80 and over; Anemia, Aplastic; Antineoplastic Combined Chemotherapy Protocols; Cause of Death; Cytarabine; Daunorubicin; Drug Administration Schedule; Feasibility Studies; Humans; Idarubicin; Infusions, Intravenous; Italy; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Remission Induction; Thioguanine | 1992 |
Remission induction and postremission therapy in acute myelogenous leukemia: British MRC Study.
Topics: Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dacarbazine; Daunorubicin; Doxorubicin; Drug Combinations; Etoposide; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Multicenter Studies as Topic; Nimustine; Prednisone; Randomized Controlled Trials as Topic; Remission Induction; Survival Rate; Thioguanine; United Kingdom; Vincristine | 1990 |
New agents in the treatment of acute myeloid leukemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cytarabine; Daunorubicin; Drug Evaluation; Etoposide; Humans; Idarubicin; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Remission Induction; Tretinoin | 1991 |
In vitro and in vivo effects of rh GM-CSF in acute myeloid leukemia (AML).
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cell Division; Cytarabine; Daunorubicin; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Infusions, Intravenous; Leukemia, Myeloid; Mitoxantrone; Recombinant Proteins; Thioguanine; Tumor Stem Cell Assay | 1991 |
Mitoxantrone and cytarabine versus daunorubicin and cytarabine in previously untreated patients with acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Prospective Studies; Remission Induction | 1991 |
Phase III trial of brief intensive treatment of adult acute lymphocytic leukemia comparing daunorubicin and mitoxantrone: a CALGB Study.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Daunorubicin; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Injections, Spinal; Male; Methotrexate; Middle Aged; Mitoxantrone; Nervous System Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1991 |
Randomized multicenter trial of cytosine arabinoside with mitoxantrone or daunorubicin in previously untreated adult patients with acute nonlymphocytic leukemia (ANLL). Lederle Cooperative Group.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Multicenter Studies as Topic; Remission Induction; Survival Rate | 1990 |
Effects of verapamil on anthracycline-induced cardiomyopathy: preliminary results of a prospective multicenter trial.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cardiomyopathies; Cytarabine; Daunorubicin; Hemodynamics; Humans; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Middle Aged; Mitoxantrone; Multicenter Studies as Topic; Prospective Studies; Randomized Controlled Trials as Topic; Thioguanine; Verapamil | 1990 |
Proposal for the classification of relapsed and refractory acute myeloid leukemias as the basis for an age-adjusted randomized comparison of sequentially applied high-dose versus intermediate-dose cytosine arabinoside in combination with mitoxantrone (S-H
Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Austria; Child; Cytarabine; Daunorubicin; Drug Resistance; Germany, West; Humans; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Middle Aged; Mitoxantrone; Multicenter Studies as Topic; Neoplasm Recurrence, Local; Prospective Studies; Randomized Controlled Trials as Topic; Thioguanine | 1990 |
Postinduction and preremission chemotherapy alternatives for adult AML: three multicenter studies of the AML Cooperative Group.
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Germany, West; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Random Allocation; Remission Induction; Thioguanine | 1987 |
Treatment of newly diagnosed acute promyelocytic leukemia (APL) by all transretinoic acid (ATRA) combined with chemotherapy: The European experience. European APL Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cell Differentiation; China; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Europe; Humans; Immunologic Factors; Leukemia, Promyelocytic, Acute; Leukocytosis; Life Tables; Middle Aged; Mitoxantrone; New York; Pilot Projects; Remission Induction; Survival Rate; Treatment Outcome; Tretinoin | 1995 |
A randomized study of mitoxantrone plus cytarabine versus daunomycin plus cytarabine in the treatment of previously untreated adult patients with acute nonlymphocytic leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Time Factors | 1994 |
[Study on the inhibitory effect of oral granisetron against nausea/vomiting induced by cytosine arabinoside containing chemotherapy for tumors in the hematopoietic organs].
Topics: Administration, Oral; Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Granisetron; Humans; Indazoles; Lymphoma; Male; Middle Aged; Mitoxantrone; Nausea; Vomiting | 1993 |
Clinical aspects of acute myeloid leukemias of the FAB types M3 and M4Eo. The AML Cooperative Group.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cause of Death; Cytarabine; Daunorubicin; Humans; Leukemia, Myelomonocytic, Acute; Leukemia, Promyelocytic, Acute; Middle Aged; Mitoxantrone; Recurrence; Remission Induction; Thioguanine | 1993 |
Recombinant human interleukin-3 (rH IL-3) in combination with remission induction chemotherapy in patients with relapsed acute myelogenous leukemia (AML): a phase I/II study.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Daunorubicin; Female; Humans; Interleukin-3; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Mitoxantrone; Platelet Count; Recombinant Proteins; Recurrence; Remission Induction | 1996 |
[Treatment results for unselected patients with acute myelogenous leukemia. During a 10-year period, August 1984 to July 1994].
Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Mitoxantrone; Patient Selection; Prednisolone; Remission Induction; Retrospective Studies; Treatment Outcome | 1996 |
Timed sequential chemotherapy for advanced acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone | 1996 |
Etoposide and mitoxantrone as a second cycle of consolidation therapy following high dose cytosine arabinoside and daunorubicin in patients with acute non-lymphocytic leukemia in remission: a pilot study.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Etoposide; Female; Follow-Up Studies; Humans; Male; Middle Aged; Mitoxantrone; Pilot Projects; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Remission Induction; Salvage Therapy | 1996 |
[Short-term intensive treatment for acute myelogenous leukemia (excluding M3 subtype) in adults].
Topics: Aclarubicin; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Middle Aged; Mitoxantrone; Time Factors; Vinblastine; Vincristine | 1997 |
[Chemotherapy schedules and bacteremia in adult patients with acute leukemia].
Topics: Acute Disease; Adolescent; Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bacteremia; Cytarabine; Daunorubicin; Drug Therapy, Combination; Etoposide; Female; Humans; Leukemia; Male; Mitoxantrone; Neutropenia; Risk Factors | 1996 |
Sequential mitoxantrone, daunorubicin, and cytosine arabinoside for patients with newly diagnosed acute myelocytic leukemia.
Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Pilot Projects | 1997 |
Autologous peripheral blood stem cell transplantation for acute myelogenous leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Leukocyte Count; Life Tables; Male; Middle Aged; Mitoxantrone; Neoplasm Recurrence, Local; Proportional Hazards Models; Prospective Studies; Remission Induction; Treatment Outcome | 1997 |
Mitoxantrone versus daunorubicin in induction-consolidation chemotherapy--the value of low-dose cytarabine for maintenance of remission, and an assessment of prognostic factors in acute myeloid leukemia in the elderly: final report. European Organization
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Prognosis; Remission Induction; Survival Analysis | 1998 |
Quality of life in adult patients with acute myeloid leukemia receiving intensive and prolonged chemotherapy -- a longitudinal study.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Longitudinal Studies; Male; Middle Aged; Mitoxantrone; Quality of Life; Thioguanine | 1998 |
Marked improvements in outcome with chemotherapy alone in paediatric acute myeloid leukemia: results of the United Kingdom Medical Research Council's 10th AML trial. MRC Childhood Leukaemia Working Party.
Topics: Acute Disease; Adolescent; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Humans; Infant; Infant, Newborn; Leukemia, Myeloid; Male; Mitoxantrone; Patient Compliance; Recurrence; Remission Induction; Survival Rate; Thioguanine; Transplantation, Autologous; Transplantation, Homologous; Treatment Outcome | 1998 |
Efficacy of dexrazoxane as a cardioprotective agent in patients receiving mitoxantrone- and daunorubicin-based chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cardiovascular Agents; Daunorubicin; Female; Heart Diseases; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Razoxane | 1998 |
Randomised unicenter trial for comparison of three regimens in de novo adult acute nonlymphoblastic leukaemia.
Topics: Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Remission Induction; Survival Analysis | 1998 |
Double induction strategy for acute myeloid leukemia: the effect of high-dose cytarabine with mitoxantrone instead of standard-dose cytarabine with daunorubicin and 6-thioguanine: a randomized trial by the German AML Cooperative Group.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cytarabine; Daunorubicin; Humans; Karyotyping; L-Lactate Dehydrogenase; Leukemia, Myeloid, Acute; Leukocyte Count; Middle Aged; Mitoxantrone; Prognosis; Remission Induction; Thioguanine; Treatment Outcome | 1999 |
Patients with de novo acute myeloid leukaemia and complex karyotype aberrations show a poor prognosis despite intensive treatment: a study of 90 patients.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Chromosome Aberrations; Cytarabine; Cytogenetic Analysis; Daunorubicin; Disease-Free Survival; Female; Follow-Up Studies; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Prognosis; Remission Induction; Thioguanine | 2001 |
Improved treatment results in high-risk pediatric acute myeloid leukemia patients after intensification with high-dose cytarabine and mitoxantrone: results of Study Acute Myeloid Leukemia-Berlin-Frankfurt-Münster 93.
Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Idarubicin; Infant; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Risk Factors; Survival Rate | 2001 |
Attempts to improve treatment outcomes in acute myeloid leukemia (AML) in older patients: the results of the United Kingdom Medical Research Council AML11 trial.
Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Administration Schedule; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Immunologic Factors; Interferon-alpha; Lenograstim; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Prednisone; Recombinant Proteins; Remission Induction; Survival Analysis; Thioguanine; Treatment Outcome; United Kingdom; Vincristine | 2001 |
Outcome after induction chemotherapy for older patients with acute myeloid leukemia is not improved with mitoxantrone and etoposide compared to cytarabine and daunorubicin: a Southwest Oncology Group study.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Remission Induction; Survival Analysis; Survival Rate; Treatment Outcome | 2002 |
6-Thioguanine, cytarabine, and daunorubicin (TAD) and high-dose cytarabine and mitoxantrone (HAM) for induction, TAD for consolidation, and either prolonged maintenance by reduced monthly TAD or TAD-HAM-TAD and one course of intensive consolidation by seq
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Prognosis; Proportional Hazards Models; Survival Analysis; Thioguanine | 2003 |
Priming with granulocyte colony-stimulating factor--relation to high-dose cytarabine in acute myeloid leukemia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Stem Cell Transplantation; Survival Analysis; Thioguanine | 2004 |
Outcome of induction and postremission therapy in younger adults with acute myeloid leukemia with normal karyotype: a cancer and leukemia group B study.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Aziridines; Benzoquinones; Cyclophosphamide; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Karyotyping; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Prognosis; Recurrence; Splenomegaly; Survival Analysis; Treatment Outcome | 2005 |
Induction chemotherapy for acute myelogenous leukemia.
Topics: Acute Disease; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Administration Schedule; Etoposide; Humans; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Remission Induction; Survival Analysis; Treatment Outcome | 2005 |
Prediction of individual response to chemotherapy in patients with acute myeloid leukaemia using the chemosensitivity index Ci.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Screening Assays, Antitumor; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Predictive Value of Tests; Prospective Studies; Sensitivity and Specificity; Survival Analysis; Thioguanine; Treatment Outcome; Tumor Cells, Cultured | 2005 |
A randomized, postremission comparison of four courses of standard-dose consolidation therapy without maintenance therapy versus three courses of standard-dose consolidation with maintenance therapy in adults with acute myeloid leukemia: the Japan Adult L
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Mitoxantrone; Probability; Remission Induction; Risk Assessment; Treatment Outcome; Vincristine; Vindesine | 2005 |
Treatment for myeloid leukaemia of Down syndrome: population-based experience in the UK and results from the Medical Research Council AML 10 and AML 12 trials.
Topics: Adolescent; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Cytogenetic Analysis; Daunorubicin; Down Syndrome; Drug Administration Schedule; Etoposide; Female; Humans; Infant; Leukemia, Myeloid; Leukocyte Count; Male; Mitoxantrone; Thioguanine; Treatment Outcome; United Kingdom | 2006 |
Early prediction of therapy response in patients with acute myeloid leukemia by nucleosomal DNA fragments.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cytarabine; Daunorubicin; DNA Fragmentation; Female; Humans; L-Lactate Dehydrogenase; Leukemia, Myeloid; Leukocytes; Male; Middle Aged; Mitoxantrone; Nucleosomes; Predictive Value of Tests; Prognosis; Thioguanine; Thymidine Kinase; Treatment Outcome | 2006 |
Less toxicity by optimizing chemotherapy, but not by addition of granulocyte colony-stimulating factor in children and adolescents with acute myeloid leukemia: results of AML-BFM 98.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cranial Irradiation; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Administration Schedule; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Infant; Infections; Leukemia, Myeloid; Male; Mitoxantrone; Neutropenia; Radiotherapy, Adjuvant; Risk Assessment; Risk Factors; Survival Analysis; Treatment Outcome | 2006 |
Effect of priming with granulocyte-macrophage colony-stimulating factor in younger adults with newly diagnosed acute myeloid leukemia: a trial by the Acute Leukemia French Association (ALFA) Group.
Topics: Acute Disease; Adolescent; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Administration Schedule; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neoplastic Stem Cells; Premedication; Proportional Hazards Models; Recombinant Proteins; Risk; Salvage Therapy; Stimulation, Chemical; Transplantation, Homologous; Treatment Outcome | 2007 |
Donor lymphocyte infusion for the treatment of leukemia relapse after HLA-mismatched/haploidentical T-cell-replete hematopoietic stem cell transplantation.
Topics: Adolescent; Adult; Antineoplastic Agents; Benzamides; Child; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Graft vs Host Disease; Graft vs Leukemia Effect; Haplotypes; Histocompatibility; HLA Antigens; Humans; Imatinib Mesylate; Immunosuppressive Agents; Kaplan-Meier Estimate; Leukemia; Lymphocyte Transfusion; Male; Methotrexate; Mitoxantrone; Pancytopenia; Peripheral Blood Stem Cell Transplantation; Piperazines; Pyrimidines; Recurrence; Remission Induction; Salvage Therapy; Tissue Donors; Treatment Outcome | 2007 |
The quality of molecular response to chemotherapy is predictive for the outcome of AML1-ETO-positive AML and is independent of pretreatment risk factors.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Core Binding Factor Alpha 2 Subunit; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Oncogene Proteins, Fusion; Prognosis; Remission Induction; Risk Factors; RNA, Messenger; RUNX1 Translocation Partner 1 Protein; Thioguanine | 2007 |
Effect and prognostic analysis of treatment for acute myeloid leukemia using Chinese drugs combined with chemotherapy.
Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Child; Chromosome Aberrations; Cytarabine; Daunorubicin; Drugs, Chinese Herbal; Etoposide; Female; Humans; Immunophenotyping; Integrative Medicine; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Prognosis; Treatment Outcome; Young Adult | 2009 |
Citrulline as a marker for chemotherapy induced mucosal barrier injury in pediatric patients.
Topics: Acute Disease; Adolescent; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Carbohydrates; Cell Death; Child; Child, Preschool; Citrulline; Cytarabine; Daunorubicin; DNA; Enterocytes; Etoposide; Feces; Female; Humans; Infant; Interleukin-8; Intestinal Absorption; Leukemia, Myeloid; Leukocyte L1 Antigen Complex; Male; Mitoxantrone; Models, Biological; Mucositis; Stomatitis | 2009 |
Daunorubicin versus mitoxantrone versus idarubicin as induction and consolidation chemotherapy for adults with acute myeloid leukemia: the EORTC and GIMEMA Groups Study AML-10.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Remission Induction; Survival Analysis; Survival Rate; Treatment Outcome; Young Adult | 2009 |
Attempts to optimize induction and consolidation treatment in acute myeloid leukemia: results of the MRC AML12 trial.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Neoplasm Staging; Prognosis; Remission Induction; Survival Rate; Thioguanine; Treatment Outcome; Tretinoin; Young Adult | 2010 |
Influence of anticancer therapy on oxidation phenotype and acetylation phenotype in patients with acute myeloblastic leukemia.
Topics: Acetylation; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Cytochrome P-450 CYP2D6; Daunorubicin; Drug Interactions; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Oxidation-Reduction; Phenotype; Young Adult | 2011 |
Results of a randomized trial in children with Acute Myeloid Leukaemia: medical research council AML12 trial.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Humans; Induction Chemotherapy; Infant; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Prognosis; Survival Analysis; Thioguanine; Treatment Outcome | 2011 |
Mutations in the DNMT3A exon 23 independently predict poor outcome in older patients with acute myeloid leukemia: a SWOG report.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; Etoposide; Exons; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Mutation; Neoplasm Staging; Prognosis; Survival Rate | 2013 |
High-dose cytarabine-based consolidation shows superior results for older AML patients with intermediate risk cytogenetics in first complete remission.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Follow-Up Studies; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Retrospective Studies; Risk Factors; Survival Rate | 2013 |
High-dose cytarabine consolidation with or without additional amsacrine and mitoxantrone in acute myeloid leukemia: results of the prospective randomized AML2003 trial.
Topics: Adolescent; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Prospective Studies; Remission Induction; Survival Analysis; Treatment Outcome; Young Adult | 2013 |
Homoharringtonine combined with cytarabine to treat chronic myelogenous leukemia in myeloid blast crisis and its impact on bone marrow CD34+CD7+ cells.
Topics: Adolescent; Adult; Antigens, CD34; Antigens, CD7; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Bone Marrow; Cell Count; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Harringtonines; Hematologic Diseases; Homoharringtonine; Humans; Immunophenotyping; Leukemia, Myeloid, Accelerated Phase; Male; Middle Aged; Mitoxantrone; Myeloid Cells; Neoplastic Stem Cells; Remission Induction; Young Adult | 2014 |
Phase II, multicenter, randomized trial of CPX-351 (cytarabine:daunorubicin) liposome injection versus intensive salvage therapy in adults with first relapse AML.
Topics: Adult; Aged; Aminoglycosides; Amsacrine; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Gemtuzumab; Humans; Injections; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Liposomes; Male; Middle Aged; Mitoxantrone; Recurrence; Remission Induction; Risk Assessment; Salvage Therapy; Treatment Outcome; Vidarabine | 2015 |
The NPM1 mutation type has no impact on survival in cytogenetically normal AML.
Topics: Adult; Aged; Antineoplastic Agents; Cytarabine; Daunorubicin; Female; fms-Like Tyrosine Kinase 3; Gene Expression; Humans; Induction Chemotherapy; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Mutation; Nuclear Proteins; Nucleophosmin; Prognosis; Remission Induction; Risk Factors; Survival Analysis; Thioguanine; Treatment Outcome | 2014 |
[Treating patients with acute myeloid leukemias (AML) according to the protocol of the AML-01.10 Russian multicenter randomized trial: the coordinating center's results].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Maintenance Chemotherapy; Male; Mitoxantrone; Russia | 2014 |
Randomized multicenter phase II study of flavopiridol (alvocidib), cytarabine, and mitoxantrone (FLAM) versus cytarabine/daunorubicin (7+3) in newly diagnosed acute myeloid leukemia.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Flavonoids; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Piperidines; Survival Rate | 2015 |
Infectious Complications in Children With Acute Myeloid Leukemia and Down Syndrome: Analysis of the Prospective Multicenter Trial AML-BFM 2004.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Down Syndrome; Etoposide; Female; Humans; Idarubicin; Infant; Infections; Leukemia, Myeloid, Acute; Male; Mitoxantrone | 2016 |
Decreased relapsed rate and treatment-related mortality contribute to improved outcomes for pediatric acute myeloid leukemia in successive clinical trials.
Topics: Adolescent; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cladribine; Clinical Protocols; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Gemtuzumab; Hematopoietic Stem Cell Transplantation; Humans; Induction Chemotherapy; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Neoplasm, Residual; Recurrence; Retrospective Studies; Survival Analysis; Time Factors; Treatment Outcome; Young Adult | 2017 |
Intermediate-dose cytarabine plus mitoxantrone versus standard-dose cytarabine plus daunorubicin for acute myeloid leukemia in elderly patients.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Remission Induction; Survival Analysis | 2018 |
Final results of a randomized multicenter phase II study of alvocidib, cytarabine, and mitoxantrone versus cytarabine and daunorubicin (7 + 3) in newly diagnosed high-risk acute myeloid leukemia (AML).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Flavonoids; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Piperidines; Risk Factors | 2018 |
Occurrence of Treatment-Related Cardiotoxicity and Its Impact on Outcomes Among Children Treated in the AAML0531 Clinical Trial: A Report From the Children's Oncology Group.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cardiotoxicity; Child; Child, Preschool; Daunorubicin; Disease-Free Survival; Echocardiography; Humans; Incidence; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Mitoxantrone; Proportional Hazards Models; Risk Factors; Survival Rate; Treatment Outcome | 2019 |
232 other study(ies) available for daunorubicin and mitoxantrone
| Article | Year |
|---|---|
Antitumor agents. 1. 1,4-Bis[(aminoalkyl)amino]-9,10-anthracenediones.
Topics: Animals; Anthracenes; Antineoplastic Agents; Leukemia, Experimental; Mice; Neoplasms, Experimental; Structure-Activity Relationship | 1979 |
Interactions of antitumor drugs with natural DNA: 1H NMR study of binding mode and kinetics.
Topics: Antineoplastic Agents; Base Composition; Chemical Phenomena; Chemistry; DNA; Hydrogen Bonding; Intercalating Agents; Kinetics; Magnetic Resonance Spectroscopy; Structure-Activity Relationship | 1984 |
Cell-based screen for identification of inhibitors of tubulin polymerization.
Topics: Animals; Brain Neoplasms; Bucladesine; Cell Differentiation; Drug Screening Assays, Antitumor; Formazans; Glioma; Rats; Tubulin; Tumor Cells, Cultured | 1996 |
Functional characterization of the human multidrug transporter, ABCG2, expressed in insect cells.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Cell Membrane; Cloning, Molecular; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Neoplasm Proteins; Recombinant Proteins; Spodoptera; Tumor Cells, Cultured | 2001 |
Rational use of in vitro P-glycoprotein assays in drug discovery.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera | 2001 |
Synthesis and cytotoxic activity of carboxamide derivatives of benzo[b][1,6]naphthyridines.
Topics: Animals; Antineoplastic Agents; Cell Division; Drug Screening Assays, Antitumor; Humans; Mice; Naphthyridines; Neoplasm Transplantation; Neoplasms, Experimental; Structure-Activity Relationship; Transplantation, Heterologous; Tumor Cells, Cultured | 2003 |
Functional characterization of human breast cancer resistance protein (BCRP, ABCG2) expressed in the oocytes of Xenopus laevis.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Oocytes; Xenopus laevis | 2003 |
Inhibitors of multidrug resistance (MDR) have affinity for MDR substrates.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Cell Membrane; Drug Resistance, Microbial; Drug Resistance, Multiple; Ligands; Models, Molecular | 2004 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Flavonoid dimers as bivalent modulators for P-glycoprotein-based multidrug resistance: synthetic apigenin homodimers linked with defined-length poly(ethylene glycol) spacers increase drug retention and enhance chemosensitivity in resistant cancer cells.
Topics: Adenosine Triphosphatases; Animals; Antineoplastic Agents; Apigenin; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Dimerization; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Mice; Paclitaxel; Polyethylene Glycols; Structure-Activity Relationship; Vinblastine | 2006 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations.
Topics: Antineoplastic Agents; Models, Chemical; Octanols; Quantitative Structure-Activity Relationship; Water | 2010 |
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.
Topics: Candida albicans; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity | 2010 |
Indeno[1,2-c]isoquinolin-5,11-diones conjugated to amino acids: Synthesis, cytotoxicity, DNA interaction, and topoisomerase II inhibition properties.
Topics: Amino Acids; Antineoplastic Agents; Arginine; Cell Line, Tumor; DNA; DNA Topoisomerases, Type II; Humans; Indenes; Isoquinolines; Mutation; Structure-Activity Relationship; Topoisomerase II Inhibitors; Transition Temperature | 2010 |
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity | 2011 |
Synthesis, cytotoxicity and topoisomerase inhibition properties of multifarious aminoalkylated indeno[1,2-c]isoquinolin-5,11-diones.
Topics: Antineoplastic Agents; Cell Line, Tumor; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Humans; Isoquinolines; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Transition Temperature | 2011 |
New derivatives of 11-methyl-6-[2-(dimethylamino)ethyl]-6H-indolo[2,3-b]quinoline as cytotoxic DNA topoisomerase II inhibitors.
Topics: Animals; Antineoplastic Agents; BALB 3T3 Cells; Cell Cycle; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Fibroblasts; HL-60 Cells; Humans; Indoles; Jurkat Cells; Male; MCF-7 Cells; Mice; Molecular Structure; Quinolines; Structure-Activity Relationship; Topoisomerase II Inhibitors | 2012 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
NAD(P)H (quinone acceptor) oxidoreductase (DT-diaphorase)-mediated two-electron reduction of anthraquinone-based antitumour agents and generation of hydroxyl radicals.
Topics: Animals; Anthraquinones; Antineoplastic Agents; Daunorubicin; Dose-Response Relationship, Drug; Hydroxides; Hydroxyl Radical; Kinetics; Liver; Mitoxantrone; NAD(P)H Dehydrogenase (Quinone); NADP; Oxidation-Reduction; Rats; Structure-Activity Relationship; Superoxides | 1992 |
The essential role of anthraquinones as substrates for NADH dehydrogenase in their redox cycling activity.
Topics: Anthraquinones; Antineoplastic Agents; Daunorubicin; Electrochemistry; Mitoxantrone; NAD; NADH Dehydrogenase; Oxidation-Reduction; Substrate Specificity; Superoxides | 1992 |
Inhibitors of topoisomerases do not block the passage of human lymphocyte chromosomes through mitosis.
Topics: Amsacrine; Camptothecin; Chromosome Aberrations; Chromosomes, Human; Daunorubicin; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Ellipticines; Ethidium; Etoposide; Humans; In Vitro Techniques; Lymphocytes; Mitosis; Mitoxantrone; Nalidixic Acid; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors | 1992 |
Dissociation of cytotoxicity and DNA cleavage activity induced by topoisomerase II-reactive intercalating agents in hamster-human somatic cell hybrids.
Topics: Animals; CHO Cells; Chromosome Mapping; Chromosomes, Human, Pair 17; Colony-Forming Units Assay; Cricetinae; Daunorubicin; DNA Damage; DNA Topoisomerases, Type II; DNA, Single-Stranded; Doxorubicin; Etoposide; Genes; Humans; Hybrid Cells; Mitoxantrone | 1992 |
Overexpression of multidrug resistance-associated p170-glycoprotein in acute non-lymphocytic leukemia.
Topics: Adolescent; Adult; Aged; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Marrow; Cytarabine; Daunorubicin; Drug Resistance; Gene Expression; Humans; Leukemia, Myeloid, Acute; Membrane Glycoproteins; Middle Aged; Mitoxantrone; Neoplasm Recurrence, Local; Remission Induction | 1992 |
In vitro effect of P-glycoprotein (P-gp) modulators on drug sensitivity of leukemic progenitors (CFU-L) in acute myelogenous leukemia (AML).
Topics: Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cefoperazone; Cyclosporine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Membrane Glycoproteins; Middle Aged; Mitoxantrone; Stem Cells; Tumor Cells, Cultured; Verapamil | 1992 |
Multidrug resistance (MDR) gene expression in acute non lymphoblastic leukemia: sequential analysis.
Topics: Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Gene Expression Regulation, Leukemic; Humans; Leukemia, Myeloid, Acute; Male; Membrane Glycoproteins; Middle Aged; Mitoxantrone; Neoplasm Proteins; Remission Induction | 1992 |
Fulminant hepatic failure after high-dose cytosine arabinoside and mitoxantrone treatment for relapse of acute myelogenous leukaemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Liver; Liver Failure, Acute; Mitoxantrone; Necrosis; Recurrence; Thioguanine | 1992 |
[A case report of an acute promyelocytic leukemia patient showing remarkable thrombopoiesis prior to granulopoiesis by hM-CSF treatment after chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Granulocytes; Hematopoiesis; Humans; Leukemia, Promyelocytic, Acute; Macrophage Colony-Stimulating Factor; Male; Middle Aged; Mitoxantrone | 1992 |
Serial changes of the serum macrophage colony-stimulating factor level after cytoreductive chemotherapy.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Enzyme-Linked Immunosorbent Assay; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Leukocyte Count; Leukopenia; Macrophage Colony-Stimulating Factor; Male; Mercaptopurine; Middle Aged; Mitoxantrone; Predictive Value of Tests; Prednisone; Remission Induction; Vindesine | 1992 |
Inhibition of DNA helicase II unwinding and ATPase activities by DNA-interacting ligands. Kinetics and specificity.
Topics: Adenosine Triphosphatases; Daunorubicin; DNA; DNA Helicases; DNA, Single-Stranded; Escherichia coli; Escherichia coli Proteins; Intercalating Agents; Kinetics; Ligands; Mitoxantrone; Nogalamycin; Substrate Specificity | 1992 |
Cost of complete remission induction in acute myeloblastic leukemia: evaluation of the cost-effectiveness of a new drug.
Topics: Antineoplastic Combined Chemotherapy Protocols; Costs and Cost Analysis; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Mitoxantrone | 1992 |
Intensive individualized induction therapy with behenoyl cytarabine, daunorubicin and 6-mercaptopurine followed by intensive consolidation including intermediate-dose continuous cytarabine, mitoxantron, etoposide and vinca alkaloids in acute myeloid leuke
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Mercaptopurine; Mitoxantrone; Vinca Alkaloids | 1991 |
[Intensification chemotherapy followed by allogenieic and autologous bone marrow transplantation in acute non-lymphoblastic leukemia in children].
Topics: Adolescent; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Daunorubicin; Etoposide; Evaluation Studies as Topic; Female; Humans; Infant; Leukemia, Myeloid, Acute; Life Tables; Male; Methotrexate; Mitoxantrone; Remission Induction; Survival Rate; Thioguanine; Transplantation, Autologous; Transplantation, Homologous | 1991 |
Recombinant human granulocyte-macrophage colony-stimulating factor after chemotherapy in patients with acute myeloid leukemia at higher age or after relapse.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Neutropenia; Recombinant Proteins; Remission Induction; Thioguanine | 1991 |
Enhancement of antitumor drug cytotoxicity via laser photoactivation.
Topics: Animals; Cell Line; Cell Survival; Daunorubicin; Lasers; Mitoxantrone; Radiation-Sensitizing Agents; Rats; Structure-Activity Relationship; Thyroid Gland | 1991 |
[Acute myeloblastic leukemia 5q-. Clinical and cytogenetic remission by means of intensive chemotherapy].
Topics: Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Chromosome Deletion; Chromosomes, Human, Pair 5; Cytarabine; Daunorubicin; Etoposide; Humans; Leukemia, Megakaryoblastic, Acute; Male; Middle Aged; Mitoxantrone; Mosaicism; Remission Induction | 1991 |
Dysmegakaryopoiesis resembling acute megakaryoblastic leukemia in treated acute myeloid leukemia.
Topics: Acute Disease; Antigens, CD; Bone Marrow; Cytarabine; Daunorubicin; Diagnosis, Differential; Doxorubicin; Etoposide; Humans; Hyperplasia; Immunophenotyping; Leukemia, Megakaryoblastic, Acute; Leukemia, Myeloid; Megakaryocytes; Mitoxantrone; Myelodysplastic Syndromes; Prognosis; Time Factors | 1991 |
In vitro chemosensitivity of newly diagnosed and relapsing acute non-lymphoid leukemia patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Resistance; Drug Screening Assays, Antitumor; Female; Humans; Idoxuridine; Iodine Radioisotopes; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Tumor Cells, Cultured | 1991 |
Aspergillus appendicitis in acute myeloid leukaemia.
Topics: Adult; Amphotericin B; Antineoplastic Combined Chemotherapy Protocols; Appendicitis; Appendix; Aspergillosis; Combined Modality Therapy; Cytarabine; Daunorubicin; Humans; Ileal Diseases; Iliac Vein; Intestinal Perforation; Ischemia; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Neutropenia; Thrombosis | 1990 |
Enzymatic studies of the effect of Cu (II) on oxygen radical production stimulated by daunorubicin and ametantrone.
Topics: Animals; Antineoplastic Agents; Copper; Cytochrome Reductases; Daunorubicin; Free Radicals; Mitoxantrone; NAD; NADH Dehydrogenase; Oxidation-Reduction; Oxygen; Superoxides | 1990 |
Magnetic resonance imaging follow-up in patients with acute leukemia during induction chemotherapy.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Daunorubicin; Humans; Leukemia; Magnetic Resonance Imaging; Middle Aged; Mitoxantrone; Remission Induction; Thioguanine | 1990 |
Acute megakaryoblastic leukemia (FAB-M7) in an infant presenting with orbital chloroma and meningeal involvement.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Etoposide; Exophthalmos; Humans; Infant; Leukemia, Megakaryoblastic, Acute; Male; Meningeal Neoplasms; Mitoxantrone; Orbital Neoplasms; Prednisone; Thioguanine; Vincristine | 1990 |
Effect of antifungal therapy on hematological recovery after intensive antileukemic chemotherapy.
Topics: Agranulocytosis; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Depression, Chemical; Hematopoiesis; Humans; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Life Tables; Mitoxantrone; Mycoses; Thioguanine; Thrombocytopenia | 1990 |
Biochemical lesions in DNA associated with the antiproliferative effects of mitoxantrone in the hepatoma cell.
Topics: Animals; Cell Division; Daunorubicin; DNA; DNA Damage; DNA, Single-Stranded; Doxorubicin; Free Radicals; Hydrogen-Ion Concentration; Mitoxantrone; Protein Biosynthesis; Rats; Tumor Cells, Cultured | 1990 |
Effects of cell density on drug-induced cell kill kinetics in vitro (inoculum effect).
Topics: Antineoplastic Agents; Bleomycin; Burkitt Lymphoma; Carboplatin; Cell Count; Cell Survival; Cisplatin; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Mitoxantrone; Organoplatinum Compounds; Vincristine | 1986 |
Multidrug resistance in a human small cell lung cancer cell line selected in adriamycin.
Topics: Animals; Antibodies, Monoclonal; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Small Cell; Cell Line; Colchicine; Daunorubicin; Doxorubicin; Drug Resistance; Enzyme-Linked Immunosorbent Assay; Epirubicin; Etoposide; Glycoproteins; Gramicidin; Humans; Immunosorbent Techniques; Isoxazoles; Lung Neoplasms; Menogaril; Mice; Mice, Inbred BALB C; Mitoxantrone; Nogalamycin; Phenotype; Vinblastine; Vincristine | 1987 |
The value of intensive combination chemotherapy for juvenile chronic myelogenous leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Child, Preschool; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Infant; Leukemia, Myeloid; Male; Mercaptopurine; Mitoxantrone; Thioguanine | 1987 |
Microsomal lipid peroxidation induced by adriamycin, epirubicin, daunorubicin and mitoxantrone: a comparative study.
Topics: Animals; beta Carotene; Carotenoids; Catalysis; Cytochrome c Group; Daunorubicin; Doxorubicin; Epirubicin; Ferritins; Iron; Lipid Peroxidation; Microsomes, Liver; Mitoxantrone; Oxidation-Reduction; Oxygen; Partial Pressure; Rats; Rats, Inbred Strains; Vitamin E | 1989 |
In vitro evaluation of the potential of aclarubicin in the treatment of small cell carcinoma of the lung (SCCL).
Topics: Aclarubicin; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood Proteins; Carcinoma, Small Cell; Daunorubicin; Doxorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Humans; In Vitro Techniques; Lung Neoplasms; Membrane Glycoproteins; Mitoxantrone; Tumor Stem Cell Assay | 1989 |
Multidrug resistance in cultured human leukemia and lymphoma cell lines detected by a monoclonal antibody, MRK16.
Topics: Antibodies, Monoclonal; ATP Binding Cassette Transporter, Subfamily B, Member 1; Dactinomycin; Daunorubicin; Doxorubicin; Drug Resistance; Etoposide; Gene Expression; Humans; Leukemia; Lymphoma; Membrane Glycoproteins; Mitoxantrone; RNA, Messenger; Tumor Cells, Cultured; Vinblastine; Vincristine; Vindesine | 1989 |
[Chemotherapy of adult ANLL].
Topics: Aclarubicin; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Daunorubicin; Drug Evaluation; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Mitoxantrone; Prednisolone; Remission Induction; Survival Rate; Vincristine | 1989 |
Use of cytotoxic drugs with an end-line filter--a study of four drugs commonly administered to paediatric patients.
Topics: Antineoplastic Agents; Daunorubicin; Doxorubicin; Filtration; Infusion Pumps; Methotrexate; Mitoxantrone; Pediatrics; Spectrophotometry | 1989 |
Calmodulin inhibitor trifluoperazine selectively enhances cytotoxic effects of strong vs weak DNA binding antitumor drugs in doxorubicin-resistant P388 mouse leukemia cells.
Topics: Aminoacridines; Amsacrine; Animals; Anthraquinones; Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Line; Dactinomycin; Daunorubicin; DNA; Doxorubicin; Drug Interactions; Drug Resistance; Leukemia P388; Leukemia, Experimental; Menogaril; Mice; Mitoxantrone; Naphthacenes; Nogalamycin; Trifluoperazine | 1985 |
Cross-resistance of menogaril and mitoxantrone in a subline of P388 leukemia resistant to doxorubicin.
Topics: Animals; Antineoplastic Agents; Body Weight; Cell Line; Daunorubicin; Doxorubicin; Drug Resistance; Leukemia P388; Life Expectancy; Menogaril; Mice; Mice, Inbred Strains; Mitoxantrone; Nogalamycin | 1987 |
Photoinduced reactions of anthraquinone antitumor agents with peptides and nucleic acid bases: an electron spin resonance and spin trapping study.
Topics: Anthraquinones; Daunorubicin; Decarboxylation; DNA; Doxorubicin; Electron Spin Resonance Spectroscopy; Free Radicals; Mitoxantrone; Nitroso Compounds; Oxygen; Peptides; Photochemistry; Pyrimidines; Solutions; Spin Labels | 1985 |
Mitoxantrone: propensity for free radical formation and lipid peroxidation--implications for cardiotoxicity.
Topics: Animals; Anthraquinones; Daunorubicin; Doxorubicin; Free Radicals; Heart; Hydrogen Peroxide; Lipid Peroxides; Mitoxantrone; Myocardium; NADP; Rabbits; Subcellular Fractions; Superoxides | 1985 |
Redox cycling of anthracyclines by cardiac mitochondria. II. Formation of superoxide anion, hydrogen peroxide, and hydroxyl radical.
Topics: Animals; Anthraquinones; Antibiotics, Antineoplastic; Cattle; Chemical Phenomena; Chemistry; Daunorubicin; Doxorubicin; Electron Spin Resonance Spectroscopy; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Methane; Mitochondria, Heart; Mitomycin; Mitomycins; Mitoxantrone; NAD; NADP; Naphthacenes; Oxidation-Reduction; Oxygen Consumption; Rotenone; Superoxides | 1986 |
Activity of (7) anthracycline related compounds in an doxorubicin sensitive human small cell lung cancer line and its doxorubicin resistant descendant. Activity of doxorubicin, daunorubicin, 4-deoxyrubicin, 4-demethoxydaunorubicin, detorubicin, 4'-epidoxo
Topics: Antibiotics, Antineoplastic; Carcinoma, Small Cell; Daunorubicin; Doxorubicin; Drug Resistance; Humans; Idarubicin; Lung Neoplasms; Mitoxantrone; Naphthacenes; Tumor Stem Cell Assay | 1987 |
Comparison of results of salvage therapy in adult acute myelogenous leukemia.
Topics: Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Doxorubicin; Drug Evaluation; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Prednisone; Prognosis; Prospective Studies; Recurrence; Regression Analysis; Retrospective Studies; Vincristine | 1987 |
Radionuclide angiographic monitoring in patients treated with potentially cardiotoxic cytostatic drugs.
Topics: Amsacrine; Antibiotics, Antineoplastic; Daunorubicin; Doxorubicin; Electrocardiography; Epirubicin; Female; Heart; Humans; Idarubicin; Male; Mitoxantrone; Prospective Studies; Radionuclide Angiography; Stroke Volume | 1988 |
A new combination of two intercalating agents (mitoxantrone + daunomycin) in adult refractory acute leukemia: the DON protocol.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Daunorubicin; Female; Humans; Intercalating Agents; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Vincristine | 1988 |
Mechanism of anthraquinone-induced calcium release from skeletal muscle sarcoplasmic reticulum.
Topics: Adenosine Triphosphate; Animals; Anthraquinones; Binding Sites; Caffeine; Calcium; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Magnesium; Mathematics; Mitoxantrone; Muscle Contraction; Muscles; Rabbits; Ryanodine; Sarcoplasmic Reticulum | 1988 |
Sequential pilot studies of intensive postremission chemotherapy for acute nonlymphocytic leukemia.
Topics: Acute Disease; Adolescent; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; Combined Modality Therapy; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia; Male; Middle Aged; Mitoxantrone; Pilot Projects; Thioguanine | 1987 |
Mitoxantrone.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cytarabine; Daunorubicin; DNA; Drug Administration Schedule; Humans; Leukemia; Mitoxantrone | 1988 |
[Phase II trial of mitoxantrone in patients with relapsed and refractory acute leukemia].
Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Aged; Blast Crisis; Child; Daunorubicin; Drug Evaluation; Drug Resistance; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Naphthacenes | 1986 |
A comparison of in vitro sensitivity of acute myeloid leukemia precursors to mitoxantrone, 4'deoxydoxorubicin, 4-demethoxydaunorubicin and daunorubicin.
Topics: Adult; Antineoplastic Agents; Colony-Forming Units Assay; Daunorubicin; Doxorubicin; Humans; Idarubicin; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Tumor Stem Cell Assay | 1986 |
Loss of fluorescence by anthracycline antibiotics: effects of xanthine oxidase and identification of the nonfluorescent metabolites.
Topics: Anaerobiosis; Animals; Anthracyclines; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Daunorubicin; Doxorubicin; Kinetics; Liver; Male; Mitoxantrone; NAD; NADP; Naphthacenes; Rats; Rats, Inbred Strains; Xanthine Oxidase | 1987 |
High-dose cytosine arabinoside and mitoxantrone: a highly effective regimen in refractory acute myeloid leukemia.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Evaluation; Drug Resistance; Heart Diseases; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Prognosis; Thioguanine | 1987 |
High-dose cytosine arabinoside in combination with mitoxantrone for the treatment of refractory acute myeloid and lymphoblastic leukemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Thioguanine | 1987 |
Pharmacokinetic study of cytosine arabinoside in patients with acute myelogeneous leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosyluracil; Cytarabine; Daunorubicin; Humans; Kinetics; Leukemia, Myeloid, Acute; Mitoxantrone; Thioguanine | 1987 |
Stopped-flow kinetic analysis of the interaction of anthraquinone anticancer drugs with calf thymus DNA, poly[d(G-C)].poly[d(G-C)], and poly[d(A-T)].poly[d(A-T)].
Topics: Anthraquinones; Antineoplastic Agents; Daunorubicin; DNA; Kinetics; Mitoxantrone; Poly dA-dT; Polydeoxyribonucleotides; Structure-Activity Relationship | 1986 |
A phase II study of mitoxantrone in acute leukemia.
Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Alanine Transaminase; Anthraquinones; Antineoplastic Agents; Child; Daunorubicin; Doxorubicin; Drug Evaluation; Drug Resistance; Electrocardiography; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukocyte Count; Male; Middle Aged; Mitoxantrone; Naphthacenes | 1985 |
Anthracenedione activation by NADPH-cytochrome P-450 reductase; comparison with anthracyclines.
Topics: Animals; Anthracenes; Anthraquinones; Antibiotics, Antineoplastic; Antineoplastic Agents; Cytochrome Reductases; Daunorubicin; Doxorubicin; Kinetics; Microsomes, Liver; Mitoxantrone; NADH Dehydrogenase; NADP; Naphthacenes; Rabbits; Superoxides | 1981 |
The electrochemical reduction of 1,4-bis-(2-[(2-hydroxyethyl)-amino] ethylamino)-anthracenedione and daunomycin: biochemical significance in superoxide formation.
Topics: Animals; Anthraquinones; Antineoplastic Agents; Daunorubicin; Electrochemistry; Electron Spin Resonance Spectroscopy; Kinetics; Male; Microsomes, Liver; Mitoxantrone; Oxidation-Reduction; Oxygen; Oxygen Consumption; Rats; Structure-Activity Relationship; Superoxides | 1983 |
[A case of refractory acute lymphocytic leukemia who achieved a complete remission by mitoxantrone].
Topics: Adult; Anthraquinones; Antineoplastic Combined Chemotherapy Protocols; Carbazilquinone; Cyclophosphamide; Daunorubicin; Drug Administration Schedule; Drug Resistance; Humans; Leukemia, Lymphoid; Male; Mitoxantrone; Nimustine; Nitrosourea Compounds; Prednisolone; Procarbazine; Vinblastine; Vincristine; Vindesine | 1984 |
[Differential cell growth inhibition and terminal differentiation induction by chemotherapeutic agents of a human acute myelogenous leukemia cell line (HL-60) in vitro].
Topics: Anthraquinones; Antineoplastic Agents; Cell Differentiation; Cell Division; Cell Line; Cell Survival; Cytarabine; Dactinomycin; Daunorubicin; Doxorubicin; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Phagocytes; Thioguanine; Vincristine | 1984 |
1,4-Bis(2-[(2-hydroxyethyl)amino]ethylamino)-9,10-anthracenedione, an anthraquinone antitumour agent that does not cause lipid peroxidation in vivo; comparison with daunorubicin.
Topics: Animals; Anthraquinones; Antineoplastic Agents; Daunorubicin; Glutathione; Lipid Peroxides; Liver; Mice; Mitoxantrone; Myocardium; Oxidation-Reduction; Oxygen Consumption | 1983 |
Inhibitory effects of anthracenedione antineoplastic agents on hepatic and cardiac lipid peroxidation.
Topics: Animals; Anthraquinones; Antineoplastic Agents; Daunorubicin; Doxorubicin; Lipid Peroxides; Liver; Male; Mitoxantrone; Myocardium; Rabbits; Rats; Rats, Inbred Strains | 1983 |
Competitive fluorescence polarization study of the binding of 1,4-dihydroxy-5,8-bis[(2-[(2-hydroxyethyl) amino] ethyl]amino] 9-10-anthracenedione to DNA.
Topics: Acridine Orange; Anthracenes; Antineoplastic Agents; Binding, Competitive; Chemical Phenomena; Chemistry; Dactinomycin; Daunorubicin; DNA; DNA, Bacterial; Doxorubicin; Fluorescence Polarization; Micrococcus; Mitoxantrone | 1980 |
Predictive value for treatment outcome in acute myeloid leukemia of cellular daunorubicin accumulation and P-glycoprotein expression simultaneously determined by flow cytometry.
Topics: Acute Disease; Adolescent; Adult; Aged; Antigens, CD; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blast Crisis; Blood Cell Count; Bone Marrow; Chromosome Deletion; Chromosomes, Human, Pair 7; Cytarabine; Daunorubicin; Drug Resistance, Multiple; Female; Flow Cytometry; Gene Expression; Humans; Idarubicin; Karyotyping; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Monosomy; Myelodysplastic Syndromes; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplastic Stem Cells; Prognosis; Prospective Studies; Quinine; Remission Induction; Risk; Salvage Therapy; Treatment Outcome | 1995 |
Granulocyte colony-stimulating factor (CSF), macrophage-CSF, granulocyte-macrophage CSF, interleukin-3, and interleukin-6 levels in sera from children undergoing blood stem cell autografts.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Child; Cytarabine; Daunorubicin; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Interleukin-6; Leukemia, Myeloid, Acute; Leukocyte Count; Lymphoma, Non-Hodgkin; Macrophage Colony-Stimulating Factor; Male; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stem Cell Transplantation; Time Factors; Transplantation, Autologous | 1993 |
[Pleomorphic T-cell lymphoma. The diagnostic problems, therapeutic possibilities and infection-induced complications].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bleomycin; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Humans; Interferon-alpha; Lymphoma, T-Cell, Peripheral; Male; Mercaptopurine; Methotrexate; Mitoxantrone; Neoplasm Recurrence, Local; Prednisone; Procarbazine; Remission Induction; Time Factors; Vincristine | 1993 |
Percentage of Philadelphia chromosome (Ph)-negative and Ph-positive cells found after autologous transplantation for chronic myelogenous leukemia depends on percentage of diploid cells induced by conventional-dose chemotherapy before collection of autolog
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Bone Marrow Transplantation; Cell Survival; Colony-Forming Units Assay; Combined Modality Therapy; Cyclophosphamide; Daunorubicin; Diploidy; Etoposide; Female; Genetic Markers; Hematopoietic Stem Cells; Humans; Idarubicin; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Accelerated Phase; Leukemia, Myeloid, Chronic-Phase; Male; Middle Aged; Mitoxantrone; Neoplastic Stem Cells; Philadelphia Chromosome; Remission Induction; Survival Rate; Vidarabine; Whole-Body Irradiation | 1995 |
In vitro anthracycline cross-resistance pattern in childhood acute lymphoblastic leukaemia.
Topics: Aclarubicin; Antibiotics, Antineoplastic; Bone Marrow; Child; Daunorubicin; Dose-Response Relationship, Drug; Drug Resistance; Humans; Idarubicin; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence | 1995 |
Doxorubicin, daunorubicin, and mitoxantrone cytotoxicity in yeast.
Topics: Daunorubicin; Doxorubicin; Electron Transport Complex IV; Mitoxantrone; Saccharomyces cerevisiae; Superoxide Dismutase | 1994 |
Benefit of high-dose cytarabine-based consolidation chemotherapy for adults with acute myelogenous leukemia.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; California; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Leukemia, Myeloid; Life Tables; Male; Middle Aged; Mitoxantrone; Preleukemia; Remission Induction; Survival Analysis; Thioguanine; Treatment Outcome | 1994 |
Acute leukemia coexpressing myeloid, B- and T-lineage associated markers: multiparameter analysis of criteria defining lineage commitment and maturational stage in a case of undifferentiated leukemia.
Topics: Acute Disease; Antigens, CD; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Marrow; Cytarabine; Daunorubicin; Fatal Outcome; Female; Hematopoietic Cell Growth Factors; Humans; Immunophenotyping; Leukemia; Middle Aged; Mitoxantrone; Neoplastic Stem Cells; Remission Induction; Thioguanine; Tumor Stem Cell Assay | 1995 |
Low frequency of activity of P-glycoprotein (P-170) in acute lymphoblastic leukemia compared to acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Marrow; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Resistance, Multiple; Female; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neoplasm Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Remission Induction; Rhodamine 123; Rhodamines; Survival Analysis | 1995 |
Collection of peripheral-blood diploid cells from chronic myelogenous leukemia patients early in the recovery phase from myelosuppression induced by intensive-dose chemotherapy.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cell Separation; Cytarabine; Daunorubicin; Diploidy; Female; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Mitoxantrone; Remission Induction; Vidarabine | 1995 |
Sequestration of doxorubicin in vesicles in a multidrug-resistant cell line (LZ-100).
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Cell Line; Cell Survival; Cricetinae; Cricetulus; Daunorubicin; Doxorubicin; Drug Resistance; Membrane Glycoproteins; Mitoxantrone | 1994 |
Interactions between cladribine (2-chlorodeoxyadenosine) and standard antileukemic drugs in primary cultures of human tumor cells from patients with acute myelocytic leukemia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amsacrine; Antineoplastic Agents; Cladribine; Cytarabine; Daunorubicin; Drug Interactions; Drug Screening Assays, Antitumor; Drug Synergism; Etoposide; Female; Fluoresceins; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Tumor Cells, Cultured | 1994 |
Post-remission cytopenias following intense induction chemotherapy for acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Anemia; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Neutropenia; Recurrence; Remission Induction; Thrombocytopenia; Time Factors; Treatment Outcome | 1994 |
[Therapy of disseminated intravascular coagulation in acute promyelocytic leukemias. Apropos of 19 cases].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Antithrombin III; Blood Coagulation Tests; Child, Preschool; Combined Modality Therapy; Cytarabine; Daunorubicin; Disseminated Intravascular Coagulation; Hemorrhage; Heparin; Humans; Leukemia, Promyelocytic, Acute; Middle Aged; Mitoxantrone; Plasma; Platelet Transfusion; Remission Induction; Treatment Outcome | 1993 |
[The comparative evaluation of the efficacy of different therapeutic plans in acute nonlymphocytic leukemias].
Topics: Aclarubicin; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Doxorubicin; Drug Evaluation; Hematopoiesis; Humans; Idarubicin; Leukemia, Myeloid, Acute; Mitoxantrone; Prednisolone; Remission Induction; Time Factors; Vincristine | 1993 |
[The current chemotherapy of acute myeloid leukemias in adults].
Topics: Aclarubicin; Acute Disease; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Humans; Idarubicin; Leukemia, Myeloid; Mitoxantrone; Prognosis; Remission Induction; Time Factors | 1993 |
In vitro cytotoxicity of mitoxantrone, daunorubicin and doxorubicin in untreated childhood acute leukemia.
Topics: Adolescent; Antineoplastic Agents; Child; Child, Preschool; Daunorubicin; Doxorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Female; Humans; Infant; Male; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured | 1994 |
[Intracellular measurement of anthracyclines with flow cytometry].
Topics: Aclarubicin; Antibiotics, Antineoplastic; Cells, Cultured; Daunorubicin; Doxorubicin; Epirubicin; Flow Cytometry; Humans; Leukocytes; Mitoxantrone | 1993 |
[Short-term intensive consolidation chemotherapy in the treatment of acute nonlymphocytic leukemia].
Topics: Aclarubicin; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Prognosis; Survival Rate; Vinblastine; Vincristine | 1994 |
Hemolytic uremic syndrome developing during remission of acute myelomonocytic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Hemolytic-Uremic Syndrome; Humans; Leukemia, Myelomonocytic, Acute; Middle Aged; Mitoxantrone; Plasma Exchange; Platelet Aggregation Inhibitors; Prednisolone; Remission Induction; Zinostatin | 1993 |
Prediction of chemotherapy response in human leukemia using in vitro chemosensitivity test.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Coloring Agents; Cytarabine; Daunorubicin; Drug Screening Assays, Antitumor; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Tetrazolium Salts; Thiazoles | 1993 |
Treatment of relapsing and refractory adult acute myeloid leukemia according to in vitro clonogenic leukemic cell drug sensitivity.
Topics: Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Humans; In Vitro Techniques; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Pilot Projects; Prospective Studies; Recurrence; Salvage Therapy; Tumor Stem Cell Assay | 1993 |
Double mutations of the N-ras gene in a patient with acute myelomonocytic leukemia.
Topics: Aclarubicin; Alleles; Antineoplastic Combined Chemotherapy Protocols; Chromosome Deletion; Chromosomes, Human, Pair 12; Chromosomes, Human, Pair 9; Codon; Cytarabine; Daunorubicin; Disease Progression; Doxorubicin; Etoposide; Fatal Outcome; Genes, ras; Genetic Vectors; Humans; Karyotyping; Leukemia, Myelomonocytic, Acute; Male; Mercaptopurine; Middle Aged; Mitoxantrone; Point Mutation; Prednisolone; Vinblastine; Vincristine | 1995 |
Invasive fungal disease in adults undergoing remission-induction therapy for acute myeloid leukemia: the pathogenetic role of the antileukemic regimen.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Fungemia; Fungi; Humans; Intestinal Mucosa; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Mycoses; Remission Induction; Retrospective Studies | 1995 |
Selective discharge of patients with acute myeloid leukemia during chemotherapy-induced neutropenia.
Topics: Acute Disease; Adult; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections; Catheterization, Central Venous; Cross Infection; Cytarabine; Daunorubicin; Disease Susceptibility; Etoposide; Female; Fever; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neutropenia; Patient Discharge; Safety; Treatment Outcome | 1996 |
Pneumocystis carinii pneumonia in adults with acute leukaemia: is there a need for primary chemoprophylaxis?
Topics: Aclarubicin; Acute Disease; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cohort Studies; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Etoposide; Female; Finland; Humans; Immunocompromised Host; Incidence; Leukemia; Male; Mercaptopurine; Methotrexate; Middle Aged; Mitoxantrone; Pneumonia, Pneumocystis; Prednisone; Premedication; Retrospective Studies; Thioguanine; Trimethoprim, Sulfamethoxazole Drug Combination; Vincristine | 1996 |
Intensive induction and consolidation chemotherapy in a young woman with acute myeloid leukemia and severe chronic renal failure.
Topics: Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Contraindications; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Kidney Failure, Chronic; Leukemia, Myeloid, Acute; Mitoxantrone | 1996 |
[Long-term selective beta 1-blockade therapy for a patient with anthracycline-induced cardiomyopathy].
Topics: Aclarubicin; Adrenergic beta-Antagonists; Adult; Antibiotics, Antineoplastic; Cardiomyopathy, Hypertrophic; Chronic Disease; Daunorubicin; Drug Administration Schedule; Female; Heart Failure; Humans; Leukemia, Myelomonocytic, Acute; Metoprolol; Mitoxantrone | 1995 |
Relation of blast cell survival and proliferation to chemotherapy resistance in AML.
Topics: Aclarubicin; Adolescent; Adult; Aged; Antineoplastic Agents; Cell Differentiation; Cell Survival; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Female; Humans; Infant; Infant, Newborn; Leukemia, Myeloid; Leukocyte Count; Male; Middle Aged; Mitoxantrone; Treatment Outcome; Tumor Cells, Cultured | 1996 |
In vitro resistance to cytosine arabinoside, not to daunorubicin, is associated with the risk of relapse in de novo acute myeloid leukaemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Amsacrine; Antigens, CD34; Antineoplastic Agents; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Recurrence; Risk Factors; Treatment Outcome | 1996 |
Expression of Fas antigen in acute myeloid leukaemia is associated with therapeutic response to chemotherapy.
Topics: Acute Disease; Adult; Antineoplastic Agents; Bone Marrow; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; fas Receptor; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Thioguanine; Treatment Outcome | 1996 |
Autologous transplantation with peripheral blood stem cells collected after granulocyte colony-stimulating factor in patients with acute myelogenous leukemia.
Topics: Acute Disease; Adolescent; Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Blood Cells; Bone Marrow; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Disease-Free Survival; Etoposide; Graft Survival; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Life Tables; Middle Aged; Mitoxantrone; Recombinant Proteins; Remission Induction; Retrospective Studies; Salvage Therapy; Survival Analysis; Thioguanine; Transplantation Conditioning; Transplantation, Autologous; Treatment Outcome; Whole-Body Irradiation | 1996 |
Superior cytotoxic potency of mitoxantrone in interaction with DNA: comparison with that of daunorubicin.
Topics: Antineoplastic Agents; Cell Division; Daunorubicin; DNA Damage; DNA-Directed DNA Polymerase; DNA, Neoplasm; Electrophoresis, Gel, Pulsed-Field; HL-60 Cells; Humans; Mitoxantrone | 1996 |
Cerebellar toxicity with medium-dose cytarabine in a young patient with renal insufficiency.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Diseases; Cytarabine; Daunorubicin; Female; Humans; Kidney; Kidney Failure, Chronic; Leukemia, Myeloid; Lupus Nephritis; Mitoxantrone | 1996 |
Acute leukemia during pregnancy: obstetric management and perinatal outcome of two cases.
Topics: Abnormalities, Drug-Induced; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Etoposide; Fatal Outcome; Female; Humans; Leukemia, Promyelocytic, Acute; Mitoxantrone; Pregnancy; Pregnancy Complications, Neoplastic; Pregnancy Outcome; Recurrence; Thioguanine | 1995 |
A simple ligation assay to detect effects of drugs on the curvature/flexibility of DNA.
Topics: Amsacrine; Antibiotics, Antineoplastic; Antineoplastic Agents; Daunorubicin; DNA; DNA Ligases; DNA, Circular; Intercalating Agents; Mitoxantrone; Nucleic Acid Conformation; Plasmids | 1996 |
[The detection of minimal residual disease by DEK/CAN chimeric m-RNA in a case of AML M2 with translocation t(6;9) (p23;q34) after chemotherapy and peripheral blood stem cell transplantation].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 6; Chromosomes, Human, Pair 9; Combined Modality Therapy; Cytarabine; Daunorubicin; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Mitoxantrone; Neoplasm, Residual; Oncogene Proteins; Oncogene Proteins, Fusion; Polymerase Chain Reaction; Prednisolone; Recombinant Fusion Proteins; RNA, Messenger; Translocation, Genetic | 1997 |
[Echocardiographic evaluation of cardiotoxicity induced by anthracycline therapy].
Topics: Aclarubicin; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Breast Neoplasms; Daunorubicin; Doxorubicin; Echocardiography; Epirubicin; Female; Heart; Hematologic Diseases; Humans; Male; Middle Aged; Mitoxantrone; Radionuclide Imaging; Stroke Volume | 1997 |
In vitro drug sensitivity testing can predict induction failure and early relapse of childhood acute lymphoblastic leukemia.
Topics: Aclarubicin; Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bleomycin; Bone Marrow; Cell Survival; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Disease-Free Survival; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Etoposide; Follow-Up Studies; Humans; Infant; Infant, Newborn; Life Tables; Melphalan; Methotrexate; Mitomycin; Mitoxantrone; Neoplastic Stem Cells; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Recurrence; Remission Induction; Tumor Cells, Cultured; Vincristine | 1997 |
Study of the apoptosis induced in vitro by antitumoral drugs on leukaemic cells.
Topics: Acute Disease; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Cell Cycle; Cytarabine; Daunorubicin; Drug Screening Assays, Antitumor; Flow Cytometry; Humans; Idarubicin; Kinetics; Leukemia; Mitoxantrone | 1997 |
The combined effects of IL-3 and PSC 833 on daunorubicin- and mitoxantrone cytotoxicity in two growth factor-dependent leukemic cell lines.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Survival; Cyclosporins; Daunorubicin; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance, Multiple; Drug Synergism; Humans; Interleukin-3; Kinetics; Leukemia; Mitoxantrone; Tumor Cells, Cultured | 1997 |
Relapse in the external auditory canal of acute promyelocytic leukemia after treatment with all-trans retinoic acid.
Topics: Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Combined Modality Therapy; Cytarabine; Daunorubicin; Ear Canal; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Mercaptopurine; Middle Aged; Mitoxantrone; Neoplasm Proteins; Oncogene Proteins, Fusion; Radiotherapy; Recurrence; Remission Induction; Salvage Therapy; Tretinoin; Vindesine | 1997 |
Effect on cell kill of addition of multidrug resistance modifiers cyclosporin A and PSC 833 to cytotoxic agents in acute myeloid leukaemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Survival; Coloring Agents; Cyclosporine; Cyclosporins; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Drug Synergism; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1997 |
MDR1 gene expression and drug resistance of AML cells.
Topics: Aclarubicin; Acute Disease; Antineoplastic Agents; Cytarabine; Daunorubicin; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Gene Expression; Genes, MDR; Humans; Lethal Dose 50; Leukemia, Myeloid; Mitoxantrone; Tumor Cells, Cultured | 1998 |
The role of intensive AML-specific therapy in treatment of children with RAEB and RAEB-t.
Topics: Adolescent; Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cell Transformation, Neoplastic; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Infant; Male; Mitoxantrone; Remission Induction | 1998 |
Management of acute promyelocytic leukemia relapse in the ATRA era.
Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Mitoxantrone; Recurrence; Remission Induction; Salvage Therapy; Thioguanine; Treatment Outcome; Tretinoin | 1998 |
Functional multidrug resistance phenotype associated with combined overexpression of Pgp/MDR1 and MRP together with 1-beta-D-arabinofuranosylcytosine sensitivity may predict clinical response in acute myeloid leukemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Biological Transport; Cytarabine; Daunorubicin; Doxorubicin; Drug Resistance, Multiple; Etoposide; Humans; KB Cells; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Multidrug Resistance-Associated Proteins; Phenotype; Prognosis; Treatment Outcome; Tumor Cells, Cultured | 1995 |
P-glycoprotein expression and prognostic value in acute myeloid leukemia.
Topics: Actuarial Analysis; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Child; Cohort Studies; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Female; Genes, MDR; Humans; Leukemia, Myeloid; Leukocyte Count; Male; Middle Aged; Mitoxantrone; Neoplasm Proteins; Neoplastic Stem Cells; Prognosis; Remission Induction | 1998 |
Prophylactic platelet transfusion threshold during therapy for adult acute myeloid leukemia: 10,000/microL versus 20,000/microL.
Topics: Acute Disease; Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Hemorrhage; Humans; Idarubicin; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Pancytopenia; Platelet Count; Platelet Transfusion; Retrospective Studies; Spain; Thrombocytopenia | 1998 |
Increased expression of annexin I and thioredoxin detected by two-dimensional gel electrophoresis of drug resistant human stomach cancer cells.
Topics: Annexin A1; Antibiotics, Antineoplastic; Antineoplastic Agents; Daunorubicin; Drug Resistance, Multiple; Electrophoresis, Gel, Two-Dimensional; Humans; Image Processing, Computer-Assisted; Mitoxantrone; Sequence Analysis, DNA; Stomach Neoplasms; Thioredoxins; Tumor Cells, Cultured | 1998 |
Daunorubicin- and mitoxantrone-triggered phosphatidylcholine hydrolysis: implication in drug-induced ceramide generation and apoptosis.
Topics: Apoptosis; Bridged-Ring Compounds; Ceramides; Daunorubicin; Diglycerides; DNA Fragmentation; Humans; Hydrolysis; Mitoxantrone; Norbornanes; Phosphatidylcholines; Protein Kinase C; Thiocarbamates; Thiones; Tumor Cells, Cultured | 1999 |
A single apheresis to achieve a high number of peripheral blood CD34+ cells in a lithium-treated patient with acute myeloid leukaemia.
Topics: Adult; Antigens, CD34; Antimanic Agents; Antineoplastic Combined Chemotherapy Protocols; Bipolar Disorder; Blood Cell Count; Cytarabine; Daunorubicin; Drug Synergism; Etoposide; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cells; Humans; Idarubicin; Leukapheresis; Leukemia, Monocytic, Acute; Lithium Carbonate; Mitoxantrone; Recombinant Proteins; Remission Induction; Thioguanine | 1999 |
Suppressed neutrophil function as a risk factor for severe infection after cytotoxic chemotherapy in patients with acute nonlymphocytic leukemia.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Fever; Humans; Idarubicin; Immunocompromised Host; Infections; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Mitoxantrone; N-Formylmethionine Leucyl-Phenylalanine; Neutropenia; Neutrophils; Phagocytosis; Respiratory Burst; Retrospective Studies; Risk Factors; Thioguanine; Vidarabine | 1999 |
A new PCR MIMIC strategy to quantify low mdr1 mRNA levels in drug resistant cell lines and AML blast samples.
Topics: Acute Disease; Adolescent; Adult; Aged; Antigens, CD34; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Chromosome Banding; Cytarabine; Daunorubicin; DNA, Complementary; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation, Leukemic; Genes, MDR; Humans; K562 Cells; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Neoplasm Proteins; Neoplastic Stem Cells; Oligonucleotide Probes; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Sensitivity and Specificity; Tumor Cells, Cultured | 1999 |
Multifocal reversible epithelial dysplasia mimicking carcinoma in situ after conditioning therapy with busulfan and cyclophosphamide.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Carcinoma in Situ; Cyclophosphamide; Cytarabine; Daunorubicin; Diagnosis, Differential; Female; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Monocytic, Acute; Mitoxantrone; Remission Induction; Thioguanine; Transplantation, Autologous; Uterine Cervical Dysplasia | 1999 |
Choroidal infiltrates simulating fundal changes of acute leukemia during hematological recovery following high-dose chemotherapy in acute myelomonocytic leukemia in remission.
Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cerebrospinal Fluid; Choroid; Cytarabine; Cytoplasmic Granules; Daunorubicin; Female; Humans; Leukemia, Myelomonocytic, Acute; Leukocyte Count; Mitoxantrone; Monocytes; Remission Induction | 2000 |
Secondary acute nonlymphocytic leukemia following successful chemotherapy combining cisplatin, doxorubicin, and cyclophosphamide for stage IV epithelial ovarian cancer.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Marrow; Cisplatin; Cyclophosphamide; Cystadenocarcinoma, Mucinous; Cytarabine; Daunorubicin; Doxorubicin; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Liver Neoplasms; Middle Aged; Mitoxantrone; Ovarian Neoplasms; Prednisolone; Remission Induction; Reoperation | 2000 |
[Retrospective study of acute myelogenous leukemia in elderly patients: treatment and outcome of 83 consecutive patients].
Topics: Age Factors; Aged; Aged, 80 and over; Chromosomes, Human, Pair 5; Chromosomes, Human, Pair 7; Cytarabine; Daunorubicin; Drug Therapy, Combination; Gene Deletion; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Remission Induction; Retrospective Studies; Treatment Outcome; Tretinoin | 2000 |
Characterisation of non-P-glycoprotein multidrug-resistant Ehrlich ascites tumour cells selected for resistance to mitoxantrone.
Topics: Adenosine Triphosphatases; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Biological Transport; Carcinoma, Ehrlich Tumor; Daunorubicin; DNA Topoisomerases, Type II; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Immunoassay; Mice; Mitoxantrone; Multidrug Resistance-Associated Proteins; Subcellular Fractions; Tumor Cells, Cultured | 2000 |
[Study on combined chemosensitivity test in acute non-lymphocytic leukemia].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Harringtonines; Homoharringtonine; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Tumor Cells, Cultured | 1998 |
In vitro drug resistance profiles of adult versus childhood acute lymphoblastic leukaemia.
Topics: Adolescent; Adult; Age Factors; Antineoplastic Agents; Asparaginase; Bone Marrow Cells; Child; Child, Preschool; Cytarabine; Daunorubicin; Dexamethasone; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Idarubicin; Ifosfamide; Infant; Leukemia, Prolymphocytic; Leukemia, T-Cell; Male; Mercaptopurine; Middle Aged; Mitoxantrone; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Statistics, Nonparametric; Teniposide; Thioguanine; Vincristine | 2000 |
Long-term remission after intensive chemotherapy in advanced myelodysplastic syndromes is generally associated with restoration of polyclonal haemopoiesis.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Daunorubicin; Dosage Compensation, Genetic; Female; Follow-Up Studies; Hematopoiesis; Humans; Idarubicin; Middle Aged; Mitoxantrone; Myelodysplastic Syndromes; Retrospective Studies; Thioguanine; Time Factors | 2000 |
Neutrophilic eccrine hidradenitis in two neutropaenic patients.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Hidradenitis; Humans; Leukemia, Myeloid; Mitoxantrone | 2001 |
[Acute myeloid leukemia in the adult. Results of the National Antineoplastic Drug Protocol at the Hospital del Salvador, 1990-1998].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Idarubicin; Immunophenotyping; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Mitoxantrone; Prognosis; Retrospective Studies; Treatment Outcome | 2000 |
Pretreatment leukaemia cell drug resistance is correlated to clinical outcome in acute myeloid leukaemia.
Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neoplastic Stem Cells; Prognosis; Remission Induction; Survival Analysis; Thioguanine; Treatment Outcome; Tumor Cells, Cultured | 2001 |
Magnetic resonance imaging detection of avascular necrosis of the bone in children receiving intensive prednisone therapy for acute lymphoblastic leukemia or non-Hodgkin lymphoma.
Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Arthralgia; Arthroplasty, Replacement, Hip; Asparaginase; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Etoposide; Female; Femur Head Necrosis; Humans; Lymphoma, Non-Hodgkin; Magnetic Resonance Imaging; Male; Mercaptopurine; Methotrexate; Mitoxantrone; Osteonecrosis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Risk Factors; Treatment Outcome; Vincristine | 2001 |
A leukemic stem cell with intrinsic drug efflux capacity in acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Benzimidazoles; Cell Separation; Child; Child, Preschool; Daunorubicin; Drug Resistance; Female; Humans; Immunophenotyping; Infant; Leukemia, Myeloid; Leukocytes, Mononuclear; Male; Mice; Mice, Inbred NOD; Middle Aged; Mitoxantrone; Myelodysplastic Syndromes; Neoplasm Transplantation; Neoplasms, Second Primary; Stem Cell Transplantation; Stem Cells; Tumor Cells, Cultured | 2001 |
In vitro effects of dexrazoxane (Zinecard) and classical acute leukemia therapy: time to consider expanded clinical trials?
Topics: Acute Disease; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cell Death; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Humans; Inhibitory Concentration 50; Leukemia; Mitoxantrone; Razoxane; Tumor Cells, Cultured | 2001 |
In vivo analysis of human multidrug resistance protein 1 (MRP1) activity using transient expression of fluorescently tagged MRP1.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bacterial Proteins; Daunorubicin; Doxorubicin; Green Fluorescent Proteins; HeLa Cells; Humans; Luminescent Proteins; Microtubules; Mitoxantrone; Protein Folding; Recombinant Fusion Proteins; Transfection | 2002 |
Hematopoietic cell transplantation beyond first remission.
Topics: Acute Disease; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Comorbidity; Cyclosporine; Cytarabine; Daunorubicin; Disease-Free Survival; Follow-Up Studies; Graft Survival; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Nuclear Family; Prospective Studies; Randomized Controlled Trials as Topic; Remission Induction; Salvage Therapy; Survival Rate; Tissue Donors; Transplantation, Homologous; Treatment Outcome; Vidarabine | 2002 |
FAB M4 and high CD14 surface expression is associated with high cellular resistance to Ara-C and daunorubicin: implications for clinical outcome in acute myeloid leukaemia.
Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Amsacrine; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cohort Studies; Cytarabine; Daunorubicin; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid; Leukemia, Myelomonocytic, Acute; Lipopolysaccharide Receptors; Male; Middle Aged; Mitoxantrone; Multivariate Analysis; Neoplastic Stem Cells; Thioguanine; Treatment Outcome | 2001 |
Modulation of the atypical multidrug-resistant phenotype by a hammerhead ribozyme directed against the ABC transporter BCRP/MXR/ABCG2.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Base Sequence; Cell Division; Cell Survival; Cell-Free System; Cisplatin; Daunorubicin; Drug Resistance, Neoplasm; Etoposide; Flow Cytometry; Humans; Mitoxantrone; Molecular Sequence Data; Neoplasm Proteins; Peptides; Phenotype; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; RNA, Catalytic; RNA, Messenger; Stomach Neoplasms; Time Factors; Transfection; Tumor Cells, Cultured | 2002 |
Multiple mechanisms confer different drug-resistant phenotypes in pancreatic carcinoma cells.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Survival; Daunorubicin; DNA Topoisomerases, Type II; Drug Resistance, Neoplasm; Humans; Kinetics; Mitoxantrone; Pancreatic Neoplasms; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 2002 |
Inhibition of basal and transforming growth factor-beta-induced stimulation of COL1A1 transcription by the DNA intercalators, mitoxantrone and WP631, in cultured human dermal fibroblasts.
Topics: Antineoplastic Agents; Apoptosis; Cell Survival; Cells, Cultured; Collagen; Collagen Type I; Collagen Type I, alpha 1 Chain; Daunorubicin; Dermis; Fibroblasts; Fibronectins; Humans; Intercalating Agents; Mitoxantrone; Promoter Regions, Genetic; Protein Binding; RNA Stability; Sp1 Transcription Factor; Transcription, Genetic; Transforming Growth Factor beta | 2002 |
CD7+ and CD56+ myeloid/natural killer cell precursor acute leukemia treated with idarubicin and cytosine arabinoside.
Topics: Acute Disease; Aged; Antigens, CD; Antigens, CD7; Antigens, Differentiation, Myelomonocytic; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; CD56 Antigen; Cytarabine; Daunorubicin; Diagnosis, Differential; Etoposide; Fatal Outcome; Humans; Idarubicin; Killer Cells, Natural; Leukemia, Myeloid; Leukemic Infiltration; Lymphoma, Non-Hodgkin; Male; Mercaptopurine; Mitoxantrone; Myeloid Cells; Neoplastic Stem Cells; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sarcoma, Myeloid; Sialic Acid Binding Ig-like Lectin 3 | 2002 |
Blast crisis of chronic myeloid leukemia: diagnosis prompted by T(8;9).
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Bone Marrow Transplantation; Child, Preschool; Chromosomes, Human, Pair 8; Chromosomes, Human, Pair 9; Combined Modality Therapy; Cytarabine; Daunorubicin; Ethmoid Sinus; Etoposide; Fusion Proteins, bcr-abl; Humans; Karyotyping; Leukemia, Myeloid, Accelerated Phase; Male; Meninges; Mitoxantrone; Remission Induction; Sacrococcygeal Region; Sarcoma, Myeloid; Thioguanine; Translocation, Genetic | 2002 |
Favorable outcome with STI571 (imatinib mesylate) and allogeneic stem cell transplantation in a case of Ph+ chemorefractory acute lymphocytic leukaemia.
Topics: Adult; Amsacrine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Betamethasone; Biomarkers, Tumor; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Female; Fusion Proteins, bcr-abl; Graft vs Host Disease; Humans; Imatinib Mesylate; Immunosuppressive Agents; Mitoxantrone; Neoplasm, Residual; Peripheral Blood Stem Cell Transplantation; Piperazines; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyrimidines; Remission Induction; Reverse Transcriptase Polymerase Chain Reaction; Transplantation, Homologous; Vincristine | 2002 |
Association of genomic imbalances with drug resistance and thermoresistance in human gastric carcinoma cells.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Chromosome Aberrations; Daunorubicin; DNA Probes; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Gene Amplification; Gene Deletion; Gene Expression Regulation; Genes, MDR; Hot Temperature; Humans; Mitoxantrone; Molecular Chaperones; Nucleic Acid Hybridization; Stomach Neoplasms; Tumor Cells, Cultured | 2003 |
Extramedullary acute myeloid leukemia (granulocytic sarcoma) with arm paresis, maculopapular exanthema and organ involvement.
Topics: Aged; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Arm; Biomarkers, Tumor; Carboxylic Ester Hydrolases; Cerebral Hemorrhage; Cytarabine; Daunorubicin; Exanthema; Fatal Outcome; Humans; Leukosialin; Male; Mitoxantrone; Neoplasm Proteins; Paresis; Sarcoma, Myeloid; Sialoglycoproteins; Skin; Stomach; Testis; Thioguanine; Vimentin | 2003 |
Reversal of breast cancer resistance protein-mediated drug resistance by tryprostatin A.
Topics: Acridines; Antineoplastic Agents; Breast Neoplasms; Cell Division; Daunorubicin; Drug Resistance, Multiple; Female; Humans; Indole Alkaloids; Kinetics; Mitoxantrone; Piperazines; Stomach Neoplasms; Tetrahydroisoquinolines; Tumor Cells, Cultured | 2003 |
Low L-selectin (CD62L) expression in acute myeloid leukemia correlates with a bad cytogenetic risk.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Chromosome Aberrations; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; L-Selectin; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neoplasm Proteins; Neoplastic Stem Cells; Remission Induction; Risk; Thioguanine; Treatment Outcome; Tretinoin | 2003 |
The interaction of daunorubicin and mitoxantrone with the red blood cells of acute myeloid leukemia patients.
Topics: Acute Disease; Adult; Aged; Daunorubicin; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Erythrocytes; Humans; Leukemia, Myeloid; Lipid Bilayers; Membrane Fluidity; Middle Aged; Mitoxantrone | 2003 |
Chloroma of the orbit in a non-leukemic adult: A case report.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Diagnosis, Differential; Humans; Male; Mitoxantrone; Orbital Neoplasms; Sarcoma, Myeloid | 2003 |
MLL/AF-1p fusion in therapy-related early pre-B acute lymphoblastic leukemia with t(1;11)(p32;q23) translocation developing in the relapse phase of acute promyelocytic leukemia.
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 11; Cytarabine; Daunorubicin; Enzyme Inhibitors; Etoposide; Fatal Outcome; Humans; Idarubicin; In Situ Hybridization, Fluorescence; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Mitoxantrone; Myeloid-Lymphoid Leukemia Protein; Neoplasm Proteins; Neoplasms, Second Primary; Oncogene Proteins, Fusion; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Topoisomerase II Inhibitors; Translocation, Genetic; Tretinoin | 2003 |
Broad-spectrum modulation of ATP-binding cassette transport proteins by the taxane derivatives ortataxel (IDN-5109, BAY 59-8862) and tRA96023.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Bridged-Ring Compounds; Cell Line, Tumor; Daunorubicin; Doxorubicin; Drug Resistance, Multiple; Humans; Mitoxantrone; Taxoids | 2004 |
Prognostic impact of early response to induction therapy as assessed by multiparameter flow cytometry in acute myeloid leukemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Cytarabine; Daunorubicin; Female; Flow Cytometry; Humans; Immunophenotyping; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neoplasm, Residual; Prognosis; Remission Induction; Stem Cell Transplantation; Survival Analysis; Thioguanine | 2004 |
Direct assessment of drug penetration into tissue using a novel application of three-dimensional cell culture.
Topics: Anthracyclines; Antibiotics, Antineoplastic; Colorectal Neoplasms; Daunorubicin; Doxorubicin; Epirubicin; HCT116 Cells; Humans; Hydrogen-Ion Concentration; Kinetics; Mitoxantrone; Spectrometry, Fluorescence; Tumor Cells, Cultured | 2004 |
Breast cancer resistance protein and P-glycoprotein in 149 adult acute myeloid leukemias.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Proliferation; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Gene Expression Regulation, Leukemic; Humans; Idarubicin; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Neoplasm Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Survival Rate | 2004 |
Acute myeloid leukemia in the elderly: etoposide when anthracyclins are contraindicated.
Topics: Aged; Aged, 80 and over; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Contraindications; Cytarabine; Daunorubicin; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Remission Induction; Retrospective Studies; Survival Analysis | 2005 |
Hypoxia-induced acidification causes mitoxantrone resistance not mediated by drug transporters in human breast cancer cells.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Glycolysis; Humans; Hydrogen-Ion Concentration; Hypoxia; Immunoblotting; Inhibitory Concentration 50; Mitoxantrone | 2005 |
Effects of peroxidase substrates on the Amplex red/peroxidase assay: antioxidant properties of anthracyclines.
Topics: Acetaminophen; Anthracyclines; Antioxidants; Daunorubicin; Doxorubicin; Electron Spin Resonance Spectroscopy; Horseradish Peroxidase; Hydrogen Peroxide; Hydroquinones; Mitoxantrone; Oxazines; Peroxidase | 2005 |
Methylxanthines (caffeine, pentoxifylline and theophylline) decrease the mutagenic effect of daunomycin, doxorubicin and mitoxantrone.
Topics: Antimutagenic Agents; Caffeine; Cell Survival; Daunorubicin; Doxorubicin; Mitoxantrone; Mutagenicity Tests; Pentoxifylline; Structure-Activity Relationship; Theophylline; Vibrio; Xanthenes | 2005 |
Prediction of doxorubicin sensitivity in breast tumors based on gene expression profiles of drug-resistant cell lines correlates with patient survival.
Topics: Algorithms; Antibiotics, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Colonic Neoplasms; Daunorubicin; Doxorubicin; Drug Resistance, Neoplasm; Female; Forecasting; Gene Expression Profiling; Humans; Mitoxantrone; Oligonucleotide Array Sequence Analysis; Predictive Value of Tests; Prognosis; Stomach Neoplasms; Survival Analysis | 2005 |
Prognostic factors and outcome of core binding factor acute myeloid leukemia patients with t(8;21) differ from those of patients with inv(16): a Cancer and Leukemia Group B study.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Aziridines; Benzoquinones; Chromosome Aberrations; Cyclophosphamide; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Prognosis; Proportional Hazards Models; Prospective Studies; Remission Induction; Statistics, Nonparametric; Survival Analysis | 2005 |
Chemotherapy for acute myeloid leukemias with cytosine arabinoside, daunorubicin, etoposide, and mitoxantrone may cause permanent oligoasthenozoospermia or amenorrhea in middle-aged patients.
Topics: Acute Disease; Adult; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Oligospermia; Sperm Motility; Spermatozoa | 2005 |
Acute myeloid leukemia treatment in patients over 60 years of age. Comparison of symptomatic, palliative, and aggressive therapy.
Topics: Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Hematopoietic Stem Cell Transplantation; Hospitalization; Humans; Hydroxyurea; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Palliative Care; Prognosis; Remission Induction; Retrospective Studies; Survival Analysis; Treatment Outcome | 2005 |
Rapid collapse of mitochondrial transmembrane potential in HL-60 cells and isolated mitochondria treated with anti-tumor 1,4-anthracenediones.
Topics: Alamethicin; Animals; Anthraquinones; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bongkrekic Acid; Calcium Chloride; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cyclosporine; Cysteine Proteinase Inhibitors; Daunorubicin; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Female; Gramicidin; HL-60 Cells; Humans; Intracellular Membranes; Ion Channels; Membrane Potentials; Mice; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitoxantrone; Ruthenium Red; Staurosporine; Ubiquinone | 2005 |
Improved outcome in childhood acute myeloid leukemia in Singapore with the MRC AML 10 protocol.
Topics: Acute Disease; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Cytarabine; Daunorubicin; Developing Countries; Disease-Free Survival; Drug Evaluation; Etoposide; Female; Gastrointestinal Diseases; Heart Diseases; Hematologic Diseases; Humans; Infant; Infections; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Mercaptopurine; Methotrexate; Mitoxantrone; Prednisone; Remission Induction; Retrospective Studies; Singapore; Survival Analysis; Thioguanine; Treatment Outcome; Vincristine | 2007 |
Functional validation of the genetic polymorphisms of human ATP-binding cassette (ABC) transporter ABCG2: identification of alleles that are defective in porphyrin transport.
Topics: Adenosine Triphosphate; Alleles; Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Camptothecin; Cell Line; Cell Survival; Chlorophyll; Daunorubicin; Doxorubicin; Drug Resistance; Hematoporphyrins; Humans; Irinotecan; Kinetics; Methotrexate; Mitoxantrone; Mutant Proteins; Mutation; Neoplasm Proteins; Polymorphism, Single Nucleotide; Porphyrins; Spodoptera; Transfection | 2006 |
Differential regulation of NF-kappaB activation and function by topoisomerase II inhibitors.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Catechin; Cell Line, Tumor; Daunorubicin; DNA Damage; Doxorubicin; Enzyme Inhibitors; Free Radicals; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Intercalating Agents; Mitoxantrone; NF-kappa B; Osteosarcoma; Oxidation-Reduction; Prognosis; Reverse Transcriptase Polymerase Chain Reaction; Topoisomerase II Inhibitors; Transcription, Genetic | 2006 |
Novel tetrahydroisoquinolin-ethyl-phenylamine based multidrug resistance inhibitors with broad-spectrum modulating properties.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Benzamides; Cell Line, Tumor; Cell Survival; Daunorubicin; Drug Design; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Isoquinolines; Mitoxantrone; Neoplasm Proteins; ortho-Aminobenzoates; Phthalic Acids; Quinolines; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2007 |
[Alteration of expression of survivin in HL-60 cells treated with chemotherapeutic drugs].
Topics: Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Daunorubicin; Drug Resistance, Neoplasm; HL-60 Cells; Humans; Inhibitor of Apoptosis Proteins; Microtubule-Associated Proteins; Mitoxantrone; Neoplasm Proteins; Oxides; RNA, Messenger; Survivin | 2006 |
In vitro and in vivo evaluation of WK-X-34, a novel inhibitor of P-glycoprotein and BCRP, using radio imaging techniques.
Topics: Antineoplastic Agents; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Benzamides; Cell Line, Tumor; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Flow Cytometry; Fluorescence; Gene Expression Regulation, Neoplastic; Humans; Mitoxantrone; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Ovarian Neoplasms; Radiopharmaceuticals; Technetium Tc 99m Sestamibi; Time Factors; Tissue Distribution; Transplantation, Heterologous; Up-Regulation | 2006 |
Upregulation of secretory connective tissue growth factor (CTGF) in keratinocyte-fibroblast coculture contributes to keloid pathogenesis.
Topics: Benzamides; Chromones; Coculture Techniques; Connective Tissue Growth Factor; Culture Media, Conditioned; Daunorubicin; Dioxoles; Enzyme Inhibitors; Fibroblasts; Humans; Immediate-Early Proteins; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Keloid; Keratinocytes; Mitoxantrone; Morpholines; Up-Regulation | 2006 |
Successful management of cerebral and pulmonary mucormycosis with liposomal amphotericin B in a 28-year-old woman with acute lymphoblastic leukemia.
Topics: Adult; Amphotericin B; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Brain Abscess; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Cytomegalovirus Infections; Daunorubicin; Dexamethasone; Etoposide; Fatal Outcome; Female; Humans; Immunocompromised Host; Liposomes; Lung Diseases, Fungal; Mercaptopurine; Mitoxantrone; Mucormycosis; Pneumonia, Viral; Postoperative Complications; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Transplantation, Homologous; Vincristine | 2006 |
Multiple drugbinding sites on the R482G isoform of the ABCG2 transporter.
Topics: Amino Acid Substitution; Animals; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Benzimidazoles; Binding Sites; Biological Transport; Cell Line; Cell Membrane; Daunorubicin; Dose-Response Relationship, Drug; Kinetics; Mitoxantrone; Neoplasm Proteins; Polymorphism, Genetic; Prazosin; Protein Binding; Protein Isoforms; Radioligand Assay; Spodoptera; Temperature; Tritium | 2006 |
Acute myelogenous leukemia associated with Ollier disease.
Topics: Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Chromosomes, Human, Pair 14; Chromosomes, Human, Pair 21; Cytarabine; Daunorubicin; Enchondromatosis; Etoposide; Gemtuzumab; Graft vs Host Disease; Humans; Infant; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Neoplastic Syndromes, Hereditary; Translocation, Genetic | 2008 |
Epithelial-mesenchymal interactions in keloid pathogenesis modulate vascular endothelial growth factor expression and secretion.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Differentiation; Cell Proliferation; Coculture Techniques; Culture Media, Conditioned; Daunorubicin; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Fibroblasts; Humans; Immunohistochemistry; Keloid; Keratinocytes; Mesoderm; Mitoxantrone; Neovascularization, Pathologic; Sirolimus; Statistics, Nonparametric; Up-Regulation; Vascular Endothelial Growth Factor A; Wound Healing | 2007 |
Monitoring of minimal residual disease in adult acute myeloid leukemia using peripheral blood as an alternative source to bone marrow.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Cells; Bone Marrow Examination; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Flow Cytometry; Humans; Idarubicin; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neoplasm, Residual; Organ Specificity; Randomized Controlled Trials as Topic; Remission Induction; Survival Analysis; Treatment Outcome | 2007 |
On the origin of the decrease in stability of the DNA hairpin d(GCGAAGC) on complexation with aromatic drugs.
Topics: Base Sequence; Binding Sites; Daunorubicin; DNA; Ethidium; Hot Temperature; Hydrocarbons, Aromatic; Mitoxantrone; Nucleic Acid Conformation; Nucleic Acid Denaturation; Pharmaceutical Preparations; Proflavine; Thermodynamics; Water | 2007 |
[A short duration treatment with intensive consolidation therapy for patients with acute myelogenous leukemia--13 year experience in a single institute].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Etoposide; Evidence-Based Medicine; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Mitoxantrone; Prednisolone; Prednisone; Quality of Life; Retrospective Studies; Survival Rate; Vincristine | 2007 |
Cardiomyopathy in children with Down syndrome treated for acute myeloid leukemia: a report from the Children's Oncology Group Study POG 9421.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cardiomyopathies; Child, Preschool; Daunorubicin; Disease-Free Survival; Down Syndrome; Female; Heart; Humans; Leukemia, Myeloid; Male; Mitoxantrone; Prospective Studies; Remission Induction; Retrospective Studies; Treatment Outcome | 2008 |
Therapeutic experience of adult acute myeloid leukemia in a single institution of China and its relationship with chromosome karyotype.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; China; Cytarabine; Cytogenetic Analysis; Daunorubicin; Female; Harringtonines; Homoharringtonine; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Prognosis; Remission Induction; Retrospective Studies; Survival Analysis | 2008 |
Difficulty of peripheral blood stem cell collection after multiple consolidation therapy in acute myeloid leukemia.
Topics: Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Lenograstim; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Neoplasm, Residual; Peripheral Blood Stem Cell Transplantation; Recombinant Proteins; Tissue and Organ Harvesting | 2008 |
CI-994 (N-acetyl-dinaline) in combination with conventional anti-cancer agents is effective against acute myeloid leukemia in vitro and in vivo.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Blood Cell Count; Cell Proliferation; Cytarabine; Daunorubicin; In Vitro Techniques; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Phenylenediamines; Rats; Rats, Inbred BN | 2008 |
Rapid complete cytogenetic remission after upfront dasatinib monotherapy in a patient with a NUP214-ABL1-positive T-cell acute lymphoblastic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Combined Modality Therapy; Cytarabine; Dasatinib; Daunorubicin; Granulocyte Colony-Stimulating Factor; Humans; In Situ Hybridization, Fluorescence; Male; Methotrexate; Mitoxantrone; Neoplasm Proteins; Neutropenia; Oncogene Proteins, Fusion; Peripheral Blood Stem Cell Transplantation; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Pyrimidines; Remission Induction; Splenic Rupture; Thiazoles; Vincristine; Young Adult | 2009 |
Future research directions for the treatment of AML.
Topics: Antineoplastic Agents; Azacitidine; Biomedical Research; Carbazoles; Carboplatin; Cytarabine; Daunorubicin; Decitabine; Enzyme Inhibitors; Etoposide; Flavonoids; Furans; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Piperidines; Quinolones; Staurosporine; Topotecan; Tretinoin | 2008 |
Continuous 24-h monitoring of electrocardiogram during anthracycline-based therapy in acute leukemia.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cardiotoxins; Cytarabine; Daunorubicin; Electrocardiography; Female; Heart Diseases; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Monitoring, Physiologic | 2009 |
Additional chromosomal abnormalities and their prognostic significance in adult Philadelphia-positive acute lymphoblastic leukemia: with or without imatinib in chemotherapy.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Benzamides; Chromosome Aberrations; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Kaplan-Meier Estimate; Male; Mercaptopurine; Methotrexate; Middle Aged; Mitoxantrone; Piperazines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Pyrimidines; Salvage Therapy; Vincristine; Vindesine; Young Adult | 2009 |
DNA damage response as a biomarker in treatment of leukemias.
Topics: Adolescent; Adult; Aged; Ataxia Telangiectasia Mutated Proteins; Biomarkers; Cell Cycle Proteins; Child; Daunorubicin; DNA Damage; DNA Topoisomerases; DNA-Binding Proteins; Enzyme Inhibitors; Histones; Humans; Idarubicin; Leukemia, Myeloid, Acute; Mitoxantrone; Phosphorylation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Serine-Threonine Kinases; Topoisomerase Inhibitors; Tumor Suppressor Proteins | 2009 |
The cytotoxic effects of gemtuzumab ozogamicin (mylotarg) in combination with conventional antileukemic agents by isobologram analysis in vitro.
Topics: Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Etoposide; Gemtuzumab; HL-60 Cells; Humans; Idarubicin; Immunotoxins; Leukemia; Mercaptopurine; Methotrexate; Mitoxantrone; Sialic Acid Binding Ig-like Lectin 3; U937 Cells; Vincristine | 2009 |
Intrathecal chemotherapy and meningeal relapses in myelomonocytic AML. A single institution experience.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Idarubicin; Injections, Spinal; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemic Infiltration; Male; Meninges; Middle Aged; Mitoxantrone; Testis; Young Adult | 2010 |
[Patients older than 80 years with de novo acute myeloid leukemias without erythroblastic and/or megakaryocytic dysplasia achieve complete remission and longer survival after classical chemotherapy 3 + 7].
Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Erythroblasts; Female; Humans; Leukemia, Myeloid, Acute; Male; Megakaryocytes; Mitoxantrone; Remission Induction; Survival Rate | 2010 |
Heart transplant in a childhood leukemia survivor: a case report.
Topics: Antineoplastic Agents; Bone Marrow Transplantation; Combined Modality Therapy; Daunorubicin; Heart Failure; Heart Transplantation; Humans; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Treatment Outcome; Young Adult | 2010 |
Early lymphocyte recovery after intensive timed sequential chemotherapy for acute myelogenous leukemia: peripheral oligoclonal expansion of regulatory T cells.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cell Separation; Cytarabine; Cytosine; Daunorubicin; Etoposide; Female; Flavonoids; Flow Cytometry; Gene Expression Profiling; Humans; Immunophenotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Piperidines; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocyte Subsets; T-Lymphocytes, Regulatory; Vidarabine; Young Adult | 2011 |
Complete remission and early death after intensive chemotherapy in patients aged 60 years or older with acute myeloid leukaemia: a web-based application for prediction of outcomes.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Germany; Humans; Internet; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Multivariate Analysis; Predictive Value of Tests; Prognosis; Regression Analysis; Remission Induction; Risk Assessment; Risk Factors; Surveys and Questionnaires; Time Factors | 2010 |
Inhibition of unwinding and ATPase activities of pea MCM6 DNA helicase by actinomycin and nogalamycin.
Topics: Adenosine Triphosphatases; Camptothecin; Cisplatin; Dactinomycin; Daunorubicin; DNA Helicases; Ellipticines; Enzyme Inhibitors; Etoposide; Intercalating Agents; Mitoxantrone; Nogalamycin; Novobiocin; Pisum sativum; Plant Proteins | 2011 |
Synthesis and biological evaluation of 4-arylcoumarin analogues of combretastatins. Part 2.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Division; Cell Line; Cell Line, Tumor; Coumarins; Crystallography, X-Ray; Daunorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; G2 Phase; Humans; Mitoxantrone; Models, Molecular; Neoplasm Proteins; Stilbenes; Structure-Activity Relationship; Tubulin; Tubulin Modulators | 2011 |
A pH-responsive cleavage route based on a metal-organic coordination bond.
Topics: Anthraquinones; Daunorubicin; Doxorubicin; Drug Delivery Systems; Hydrogen-Ion Concentration; Metals; Mitoxantrone; Models, Molecular; Nanoparticles; Phenanthrolines | 2011 |
In vitro synergism between LFA-1 targeting leukotoxin (Leukothera™) and standard chemotherapeutic agents in leukemia cells.
Topics: Adenosine Triphosphate; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzamides; Busulfan; Cell Line, Tumor; Daunorubicin; Drug Interactions; Drug Synergism; Etoposide; Exotoxins; Flow Cytometry; Humans; Imatinib Mesylate; Immunosuppressive Agents; Leukemia; Leukocytes; Lymphocyte Function-Associated Antigen-1; Membrane Potential, Mitochondrial; Mitoxantrone; Piperazines; Pyrimidines; Tumor Cells, Cultured | 2011 |
Structure-activity relationship and molecular mechanisms of ethyl 2-amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (CXL017) and its analogues.
Topics: Antineoplastic Agents; Benzopyrans; Cell Line, Tumor; Cell Survival; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; HCT116 Cells; HL-60 Cells; HT29 Cells; Humans; Inhibitory Concentration 50; K562 Cells; Mitoxantrone; Molecular Structure; Neoplasms; Paclitaxel; Stereoisomerism; Structure-Activity Relationship; Vincristine | 2011 |
Glycolysis inhibition inactivates ABC transporters to restore drug sensitivity in malignant cells.
Topics: Adenosine Triphosphate; Antineoplastic Agents; ATP-Binding Cassette Transporters; Base Sequence; Cell Line, Tumor; Daunorubicin; DNA Primers; Doxorubicin; Flow Cytometry; Glycolysis; Humans; Mitoxantrone; Real-Time Polymerase Chain Reaction | 2011 |
Feasibility of outpatient consolidation chemotherapy in older versus younger patients with acute myeloid leukemia.
Topics: Acute Disease; Adult; Age Factors; Aged; Aged, 80 and over; Ambulatory Care; Anti-Infective Agents; Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Etoposide; Feasibility Studies; Female; Humans; Infections; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neutropenia; Outpatients; Patient Readmission | 2012 |
Flow cytometry-based assessment of mitoxantrone efflux from leukemic blasts varies with response to induction chemotherapy in acute myeloid leukemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cyclosporine; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Female; Flow Cytometry; Humans; Induction Chemotherapy; Karyotype; Leukemia, Myeloid, Acute; Lymphoid Progenitor Cells; Male; Middle Aged; Mitoxantrone; Neoplasm Proteins; Statistics, Nonparametric; Young Adult | 2012 |
Outcome of elderly patients with acute promyelocytic leukemia: results of the German Acute Myeloid Leukemia Cooperative Group.
Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Bone Marrow; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Follow-Up Studies; Germany; Humans; Kaplan-Meier Estimate; Leukemia, Promyelocytic, Acute; Leukocyte Count; Maintenance Chemotherapy; Male; Middle Aged; Mitoxantrone; Multicenter Studies as Topic; Oxides; Prognosis; Randomized Controlled Trials as Topic; Remission Induction; Risk; Thioguanine; Treatment Outcome; Tretinoin | 2013 |
A case report of acute myeloid leukemia after liver transplantation.
Topics: Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Bone Marrow; Cytarabine; Daunorubicin; Hepatitis B; Humans; Leukemia, Myeloid, Acute; Liver Cirrhosis; Liver Transplantation; Male; Middle Aged; Mitoxantrone; Oxides; Tretinoin | 2013 |
Dermatic Scedosporium apiospermum infection after autologous bone marrow transplantation.
Topics: Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Dermatomycoses; Drugs, Chinese Herbal; Humans; Immunocompromised Host; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Male; Mitoxantrone; Opportunistic Infections; Postoperative Complications; Pyrimidines; Scedosporium; Skin Ulcer; Transplantation Conditioning; Transplantation, Autologous; Triazoles; Voriconazole; Young Adult | 2013 |
Outcomes of elderly de novo acute myeloid leukemia treated by a risk-adapted approach based on age, comorbidity, and performance status.
Topics: Aged; Aged, 80 and over; Allografts; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Comorbidity; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Etoposide; Female; Gemtuzumab; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Remission Induction; Risk; Severity of Illness Index; Treatment Outcome | 2013 |
[Pulmonary differentiation -/ATRA syndrome within the scope of therapy of acute promyelocytic leukemia (APL)].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Diagnosis, Differential; Dyspnea; Female; Follow-Up Studies; Humans; Induction Chemotherapy; Leukemia, Promyelocytic, Acute; Middle Aged; Mitoxantrone; Pleural Effusion; Pulmonary Edema; Thioguanine; Tomography, X-Ray Computed; Tretinoin | 2014 |
Mitoxantrone as a substitute for daunorubicin during induction in newly diagnosed lymphoblastic leukemia and lymphoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Daunorubicin; Dexamethasone; Drug Substitution; Female; Follow-Up Studies; Humans; Male; Mitoxantrone; Polyethylene Glycols; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Remission Induction; Vincristine | 2014 |
Acute myeloid leukemia of mixed megakaryocytic and erythroid origin following chemotherapy for T-cell lymphoblastic lymphoma.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cytarabine; Daunorubicin; Dexamethasone; Erythroid Cells; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Mediastinal Neoplasms; Megakaryocytes; Mitoxantrone; Neoplasms, Second Primary; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Vincristine | 2014 |
[Treatment of acute myeloid leukemia -- a single center experience (2007-2013)].
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Cytarabine; Daunorubicin; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Hungary; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Neoplasm, Residual; Palliative Care; Prognosis; Pyrazines; Retrospective Studies; Survival Analysis; Survival Rate; Transplantation, Homologous; Treatment Outcome; Vidarabine | 2014 |
Identification of genomic biomarkers for anthracycline-induced cardiotoxicity in human iPSC-derived cardiomyocytes: an in vitro repeated exposure toxicity approach for safety assessment.
Topics: Anthracyclines; Antibiotics, Antineoplastic; Biomarkers, Pharmacological; Cardiotoxins; Cells, Cultured; Computational Biology; Daunorubicin; Doxorubicin; Drug Evaluation, Preclinical; Drugs, Investigational; Gene Expression Profiling; Gene Expression Regulation; Humans; Induced Pluripotent Stem Cells; Mitoxantrone; Molecular Sequence Annotation; Myocytes, Cardiac; Oligonucleotide Array Sequence Analysis; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Topoisomerase II Inhibitors; Toxicity Tests, Chronic | 2016 |
Rheumatoid Arthritis Disease Activity Is Determinant for ABCB1 and ABCG2 Drug-Efflux Transporters Function.
Topics: Adult; Arthritis, Rheumatoid; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; Biological Transport; Daunorubicin; Demography; Female; Flow Cytometry; Follow-Up Studies; Humans; Linear Models; Male; Mitoxantrone; Neoplasm Proteins; Remission Induction; Young Adult | 2016 |
ABC-transporter blockage mediated by xanthotoxin and bergapten is the major pathway for chemosensitization of multidrug-resistant cancer cells.
Topics: 5-Methoxypsoralen; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Proliferation; Cell Survival; Cisplatin; Daunorubicin; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Kinetics; MCF-7 Cells; Methoxsalen; Mitoxantrone; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Neoplasms | 2017 |
Efficacy of common salvage chemotherapy regimens in patients with refractory or relapsed acute myeloid leukemia: A retrospective cohort study.
Topics: Aclarubicin; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cohort Studies; Cytarabine; Daunorubicin; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Harringtonines; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Retrospective Studies; Salvage Therapy; Survival Rate; Treatment Outcome; Vidarabine; Young Adult | 2018 |
Results of program acute myeloid leukemia therapy use in National Medical Research Center for Hematology of the Ministry of Health of Russian Federation.
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Prognosis; Russia; Survival Rate; Young Adult | 2018 |
G-quadruplex forming region within WT1 promoter is selectively targeted by daunorubicin and mitoxantrone: A possible mechanism for anti-leukemic effect of drugs.
Topics: Cell Line, Tumor; Circular Dichroism; Daunorubicin; Electrophoresis, Polyacrylamide Gel; Electrophoretic Mobility Shift Assay; G-Quadruplexes; Gene Expression Regulation, Leukemic; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Promoter Regions, Genetic; WT1 Proteins | 2019 |
Acid ceramidase promotes drug resistance in acute myeloid leukemia through NF-κB-dependent P-glycoprotein upregulation.
Topics: Acid Ceramidase; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cell Survival; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Flow Cytometry; HEK293 Cells; HL-60 Cells; Humans; In Vitro Techniques; Lentivirus; Leukemia, Myeloid, Acute; Mitoxantrone; NF-kappa B; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Tandem Mass Spectrometry | 2019 |
Pharmacological inhibition of tumor anabolism and host catabolism as a cancer therapy.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Daunorubicin; Energy Metabolism; Gene Expression Regulation, Neoplastic; Glycolysis; Growth Hormone; Humans; Indazoles; Indomethacin; Insulin; Metabolic Networks and Pathways; Metabolism; Mice; Mitoxantrone; Orlistat; Oxidative Phosphorylation; Vincristine | 2021 |
Improvement of cytotoxicity of mitoxantrone and daunorubicin by candidone, tephrosin, and bavachinin.
Topics: Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Cytotoxins; Daunorubicin; Female; Flavonoids; Humans; MCF-7 Cells; Mitoxantrone; Neoplasm Proteins; Rotenone; Stomach Neoplasms | 2021 |
Dabrafenib inhibits ABCG2 and cytochrome P450 isoenzymes; potential implications for combination anticancer therapy.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; Cell Line, Tumor; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Daunorubicin; Dogs; Drug Therapy, Combination; Gene Expression Regulation; Humans; Imidazoles; Mitoxantrone; Oximes; RNA, Messenger | 2022 |
Different treatment strategies versus a common standard arm (CSA) in patients with newly diagnosed AML over the age of 60 years: a randomized German inter-group study.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Prognosis; Remission Induction | 2023 |