daunorubicin has been researched along with melphalan in 47 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (46.81) | 18.7374 |
| 1990's | 11 (23.40) | 18.2507 |
| 2000's | 9 (19.15) | 29.6817 |
| 2010's | 5 (10.64) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Atassi, G; Baron, M; Bissery, MC; Cros, S; Gebel-Servolles, P; Giorgi-Renault, S; Lavelle, F; Paoletti, C; Renault, J | 1 |
| Hansch, C; Khwaja, TA; Selassie, CD | 1 |
| Barrows, LR; Ireland, CM; Kokoshka, JM | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Avdeef, A; Sun, N; Tam, KY; Tsinman, O | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Benfenati, E; Raska, I; Toropov, AA; Toropova, AP | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Borisov, VI | 1 |
| Sullivan, MP; Sutow, WW | 1 |
| Ames, BN; Baker, MS; Benedict, WF; Choi, E; Haroun, L | 1 |
| Bech-Hansen, NT; Ling, V; Sarangi, F; Sutherland, DJ | 1 |
| Davisson, PJ; Gregoriadis, G; Scott, S | 1 |
| Ascari, E; Danova, M; Giordano, M; Invernizzi, R; Luoni, R; Rastaldi, MP; Riccardi, A; Ucci, G; Zambelli, ML | 1 |
| Abdulkadyrov, KM; Bessmel'tsev, SS; Liubimova, NIu | 1 |
| Abdulkadyrov, KM; Bessmel'tsev, SS; Katsadze, IuL | 1 |
| Brusentsov, NA; Glazkova, TIu; Iavorskaia, NP; Iurchenko, NIa | 1 |
| Bell, JB; Gore, ME; Maitland, JA; McElwain, TJ; Millar, BC; Selby, PJ; Zuiable, A | 1 |
| Adams, EG; Bhuyan, BK; Crampton, SL; Johnson, M | 1 |
| Ishikawa, E; Kawakami, M; Kuraishi, Y; Meguro, S; Tanaka, H | 1 |
| Atanasian, LA; Savinova, VF; Toloknov, BO | 1 |
| Biondo, F; Caramia, G; Gebbia, N; Pavone-Macaluso, M; Rausa, L; Rizzo, FP | 1 |
| Zubrod, CG | 1 |
| Frei, E; Goldin, A; Schabel, FM | 1 |
| Parker, AC | 1 |
| Berndt, H; Rieche, K | 1 |
| Ravina, A | 1 |
| Donaldson, MH; Fernbach, DJ; Lane, DM; Lonsdale, D; Sutow, WW; Vietti, TJ | 1 |
| Molteni, P; Zearo, C | 1 |
| Dantas, M; Drebing, C; Glode, LM; Koeppler, H; Robinson, WA; Thomas, MR | 1 |
| Bizer, VA; Timukhina, VN | 2 |
| Kabiev, OK; Rakhimov, KD; Vermenichev, SM | 1 |
| Baral, E; Blomgren, H; Wasserman, J | 1 |
| Chatterjee, R; Goldstone, AH; Katz, M; McGarrigle, HH; Mills, W | 1 |
| Mikhalev, II; Molotkovskiĭ, IuG; Nikol'skiĭ, PIu; Vodovozova, EL | 1 |
| Hanada, R; Hongo, T; Horikoshi, Y; Sakurai, M; Yajima, S | 1 |
| Rekhtina, IG; Shchekochikhin, SM | 1 |
| Baranov, AE; Konchalovskiĭ, MV; Melkova, KN; Obukhova, EE; Tugova, SV | 1 |
| Binder, AB; Bohm, LJ; Serafin, AM | 1 |
| Bengala, C; Biadi, O; Conte, PF; Danesi, R; Del Tacca, M; Donati, S; Favre, C; Fogli, S; Guarneri, V; Innocenti, F; Mariani, M; Pazzagli, I | 1 |
| Damon, L; Demirer, T; Derigs, G; Ferrante, P; Kröger, N; Rosti, G; Wandt, H; Zander, AR | 1 |
| Anestål, K; Arnér, ES; Ehrsson, H; Jerremalm, E; Witte, AB | 1 |
| Azzam, K; Hasmann, M; Nüssler, V; Pelka-Fleischer, R; Pogrebniak, A; Schemainda, I | 1 |
| Binder, A; Bohm, L; Donninger, H; Parker, MI | 1 |
| Gullbo, J; Haglund, C; Hassan, SB; Höglund, M; Larsson, R; Strese, S; Velander, E | 1 |
4 review(s) available for daunorubicin and melphalan
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Soviet antitumor preparations.
Topics: Animals; Antineoplastic Agents; Aziridines; Butylated Hydroxytoluene; Dactinomycin; Daunorubicin; Humans; Melphalan; Methylnitrosourea; Neoplasms, Experimental; Nitrogen Mustard Compounds; Olivomycins; Organophosphorus Compounds; Phenylalanine; Prospidium; Pyrimidines; Spiro Compounds; Streptonigrin; Tegafur; Triethylenephosphoramide; Uracil | 1977 |
[Burkitt's lymphoma and acute leukemias].
Topics: Acute Disease; Animals; Asparaginase; Burkitt Lymphoma; Child; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Fluorouracil; Humans; Leukemia; Melphalan; Mercaptopurine; Methotrexate; Mice; Oncogenic Viruses; Prednisolone; Prednisone; Vincristine | 1969 |
Secondary acute leukemia following mitoxantrone-based high-dose chemotherapy for primary breast cancer patients.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Epirubicin; Female; Humans; Incidence; Leukemia, Myeloid; Leukemia, Myelomonocytic, Acute; Leukemia, Promyelocytic, Acute; Leukemia, Radiation-Induced; Lymphatic Metastasis; Melphalan; Middle Aged; Mitoxantrone; Neoplasms, Second Primary; Paclitaxel; Peripheral Blood Stem Cell Transplantation; Radiotherapy, Adjuvant; Thiotepa; Transplantation Conditioning; Transplantation, Autologous | 2003 |
43 other study(ies) available for daunorubicin and melphalan
| Article | Year |
|---|---|
Heterocyclic quinones. 17. A new in vivo active antineoplastic drug: 6,7-bis(1-aziridinyl)-4-[[3-(N,N-dimethylamino)propyl]amino]-5,8- quinazolinedione.
Topics: Animals; Antineoplastic Agents; Aziridines; Breast Neoplasms; Cell Division; Cell Line; Drug Screening Assays, Antitumor; Female; Humans; Leukemia L1210; Leukemia, Experimental; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Molecular Structure; Neoplasms, Experimental; Quinazolines; Sarcoma, Experimental; Structure-Activity Relationship | 1991 |
Structure-activity relationships of antineoplastic agents in multidrug resistance.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured | 1990 |
Cell-based screen for identification of inhibitors of tubulin polymerization.
Topics: Animals; Brain Neoplasms; Bucladesine; Cell Differentiation; Drug Screening Assays, Antitumor; Formazans; Glioma; Rats; Tubulin; Tumor Cells, Cultured | 1996 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
The permeation of amphoteric drugs through artificial membranes--an in combo absorption model based on paracellular and transmembrane permeability.
Topics: Caco-2 Cells; Cell Membrane Permeability; Humans; Hydrogen-Ion Concentration; Membranes, Artificial; Molecular Structure; Pharmaceutical Preparations | 2010 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations.
Topics: Antineoplastic Agents; Models, Chemical; Octanols; Quantitative Structure-Activity Relationship; Water | 2010 |
Childhood cancer: the improving prognosis.
Topics: Asparaginase; Child; Cyclophosphamide; Cytosine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Hodgkin Disease; Humans; Infant; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Melphalan; Mercaptopurine; Methotrexate; Neoplasms; Nitrogen Mustard Compounds; Osteosarcoma; Prednisone; Procarbazine; Prognosis; Remission, Spontaneous; Rhabdomyosarcoma; Teniposide; Thioguanine; Vincristine; Wilms Tumor | 1976 |
Mutagenicity of cancer chemotherapeutic agents in the Salmonella/microsome test.
Topics: 2-Naphthylamine; Animals; Antineoplastic Agents; Carcinogens; Cisplatin; Cyclophosphamide; Daunorubicin; Doxorubicin; Drug Evaluation, Preclinical; Hycanthone; Ifosfamide; In Vitro Techniques; Male; Mechlorethamine; Melphalan; Mercaptopurine; Mesylates; Microsomes, Liver; Mutagens; Nitrogen Mustard Compounds; Propylamines; Rats; Salmonella typhimurium; Thiotepa; Tilorone; Uracil Mustard | 1977 |
Rapid assays for evaluating the drug sensitivity of tumor cells.
Topics: Antineoplastic Agents; Ascitic Fluid; Cell Division; Cell Line; Daunorubicin; DNA, Neoplasm; Doxorubicin; Drug Evaluation, Preclinical; Drug Resistance; Humans; In Vitro Techniques; Melphalan; Methotrexate; Neoplasms; Phenotype; Pleural Effusion; Puromycin; RNA, Neoplasm; Vinblastine | 1977 |
Binding of drugs to liposome-entrapped macromolecules prevents diffusion of drugs from liposomes in vitro and in vivo [proceedings].
Topics: Animals; Daunorubicin; Diffusion; Kinetics; Liposomes; Melphalan; Rats | 1977 |
[p170 in multiple myeloma and acute leukemia].
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biomarkers, Tumor; Colonic Neoplasms; Cytarabine; Daunorubicin; Drug Resistance; Female; Gene Expression Regulation, Neoplastic; Humans; Leukemia; Male; Melphalan; Membrane Glycoproteins; Middle Aged; Multiple Myeloma; Neoplasm Proteins; Neoplastic Stem Cells; Peptichemio; Plasma Cells; Prednisone; Remission Induction; Survival Rate; Tumor Cells, Cultured; Vincristine | 1991 |
[Immunological and rheological disorders in multiple myeloma patients].
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood Viscosity; Chronic Disease; Cyclophosphamide; Daunorubicin; Female; Heart Failure; Humans; Immunity, Cellular; Kidney Failure, Chronic; Male; Melphalan; Middle Aged; Multiple Myeloma; Nitrogen Mustard Compounds; Prednisolone; Vincristine | 1991 |
[The effect of different programs of cytostatic therapy on the blood coagulation and rheological properties in multiple myeloma patients].
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood Coagulation; Blood Viscosity; Chronic Disease; Cyclophosphamide; Daunorubicin; Drug Evaluation; Female; Humans; Male; Melphalan; Middle Aged; Multiple Myeloma; Nitrogen Mustard Compounds; Prednisolone; Vincristine | 1991 |
[Antineoplastic activity of combinations of cytostatics and dextran-ferrite administered to mice with leukemia P-388].
Topics: Animals; Antineoplastic Agents; Cisplatin; Cyclophosphamide; Dactinomycin; Daunorubicin; Doxorubicin; Drug Combinations; Fluorouracil; Iron-Dextran Complex; Leukemia P388; Melphalan; Methotrexate; Mice; Tegafur | 1990 |
In vitro studies of ways to overcome resistance to VAMP--high dose melphalan in the treatment of multiple myeloma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cell Survival; Colony-Forming Units Assay; Daunorubicin; Doxorubicin; Drug Resistance; Humans; Melphalan; Methylprednisolone; Multiple Myeloma; Tumor Cells, Cultured; Tumor Stem Cell Assay; Verapamil; Vincristine | 1989 |
Synergistic combination of menogarol and melphalan and other two drug combinations.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cell Survival; Cells, Cultured; Daunorubicin; Doxorubicin; Drug Synergism; Melanoma; Melphalan; Menogaril; Mice; Nogalamycin | 1985 |
A comparative pathological study of liver injury after different combination chemotherapies for leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Liver; Melphalan; Prednisolone; Prednisone; Thioguanine | 1988 |
[Treatment of isolated metastases from choriocarcinoma of the uterus to the lung].
Topics: Adult; Antineoplastic Agents; Choriocarcinoma; Colchicine; Dactinomycin; Daunorubicin; Female; Flavonoids; Humans; Lung Neoplasms; Melphalan; Mercaptopurine; Methotrexate; Middle Aged; Mitomycins; Neoplasm Metastasis; Olivomycins; Pneumonectomy; Pregnancy; Uterine Neoplasms; Vinblastine | 1974 |
Experimental techniques for testing the sensitivity of bladder tumours to antineoplastic drugs.
Topics: Administration, Topical; Animals; Antineoplastic Agents; Carcinoma, Transitional Cell; Cell Nucleus; Cricetinae; Cytotoxicity Tests, Immunologic; Daunorubicin; Demecolcine; DNA, Neoplasm; Doxorubicin; Drug Resistance; Fluorescence; Glycosides; Humans; Melphalan; Microscopy, Fluorescence; Neoplasm Transplantation; Oxidoreductases; Podophyllotoxin; Protein Biosynthesis; Thiophenes; Thiotepa; Transplantation, Heterologous; Urinary Bladder Neoplasms | 1973 |
Acute leukemias and Burkitt's lymphoma. Present status of therapy.
Topics: Antineoplastic Agents; Asparaginase; Burkitt Lymphoma; Choriocarcinoma; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Female; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Melphalan; Mercaptopurine; Methotrexate; Prednisone; Pregnancy; Vincristine; Wilms Tumor | 1968 |
Comparative chemotherapy of AKR lymphoma and human hematological neoplasia.
Topics: Animals; Antineoplastic Agents; Biological Assay; Carmustine; Cyclohexanes; Cyclophosphamide; Cytarabine; Daunorubicin; Disease Models, Animal; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Fluorouracil; Hodgkin Disease; Humans; Leukemia; Leukemia L1210; Leukemia, Experimental; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Male; Mechlorethamine; Melphalan; Mice; Mice, Inbred AKR; Multiple Myeloma; Nitrosourea Compounds; Prednisone; Remission, Spontaneous; Vinblastine; Vincristine | 1974 |
A case of acute myelomonocytic leukaemia associated with myelomatosis.
Topics: Aged; Autopsy; Blood Cell Count; Blood Protein Disorders; Blood Protein Electrophoresis; Bone Marrow; Bone Marrow Cells; Cytarabine; Daunorubicin; Humans; Immunoelectrophoresis; Immunoglobulin G; Leukemia, Myeloid; Male; Melphalan; Multiple Myeloma; Prednisone | 1973 |
[Chemotherapy of cancer. Hints for continuing medical education].
Topics: Antineoplastic Agents; Busulfan; Chlorambucil; Cyclophosphamide; Cytarabine; Daunorubicin; Education, Medical, Continuing; Fluorouracil; Humans; Melphalan; Mercaptopurine; Methotrexate; Neoplasms; Procarbazine; Triaziquone; Vinblastine; Vincristine | 1974 |
Evaluation of chemotherapy in children with metastatic Ewing's sarcoma and osteogenic sarcoma.
Topics: Adolescent; Amines; Antineoplastic Agents; Child; Child, Preschool; Cyclophosphamide; Daunorubicin; Female; Humans; Hydroxyurea; Male; Melphalan; Neoplasm Metastasis; Nitrosourea Compounds; Osteosarcoma; Sarcoma, Ewing; Triazines; Uracil Mustard; Vincristine | 1971 |
[Oral cytology during antiblastic treatment].
Topics: Antineoplastic Agents; Cyclophosphamide; Dactinomycin; Daunorubicin; Female; Genital Neoplasms, Female; Humans; Melphalan; Methotrexate; Mouth Mucosa | 1969 |
Autologous marrow transplantation for patients with chronic myelogenous leukemia (CML) in blast crisis.
Topics: Adult; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Doxorubicin; Female; Freezing; Humans; Hydroxyurea; Leukemia, Myeloid; Male; Melphalan; Middle Aged; Teniposide; Thioguanine; Tissue Preservation; Transplantation, Autologous | 1984 |
[Treatment results in osteogenic sarcoma in children and adolescents with the use of karminomycin].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carubicin; Child; Child, Preschool; Combined Modality Therapy; Daunorubicin; Drug Evaluation; Follow-Up Studies; Humans; Lung Neoplasms; Lymphatic Metastasis; Melphalan; Osteosarcoma; Time Factors; Vincristine | 1984 |
[Hematopoietic resistance to the damaging action of cytostatics in the occurrence of tumor drug resistance].
Topics: Animals; Daunorubicin; Drug Evaluation, Preclinical; Drug Resistance; Drug Therapy, Combination; Flavonoids; Fluorouracil; Hematopoiesis; Lymphoma, Non-Hodgkin; Male; Melphalan; Neoplasm Transplantation; Neoplasms, Experimental; Rats | 1981 |
The effect of some cytotoxic agents on lymphocyte subpopulations in vitro.
Topics: Adult; Cell Survival; Cells, Cultured; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Female; Humans; Leukocyte Count; Lymphocytes; Male; Melphalan; Middle Aged; Rosette Formation; T-Lymphocytes | 1980 |
[Polychemotherapy using carminomycin in the combined treatment of the disseminated form of Ewing's sarcoma in children].
Topics: Adolescent; Carubicin; Child; Child, Preschool; Cyclophosphamide; Daunorubicin; Drug Evaluation; Drug Therapy, Combination; Humans; Melphalan; Neoplasm Metastasis; Radiotherapy Dosage; Sarcoma, Ewing | 1981 |
Induction of ovarian function by using short-term human menopausal gonadotrophin in patients with ovarian failure following cytotoxic chemotherapy for haematological malignancy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow Transplantation; Carmustine; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Female; Follicle Stimulating Hormone; Hodgkin Disease; Humans; Leukemia, Myelomonocytic, Acute; Luteinizing Hormone; Melphalan; Menotropins; Ovulation Induction; Podophyllotoxin; Prednisone; Pregnancy; Pregnancy, Multiple; Primary Ovarian Insufficiency; Remission Induction; Teniposide; Thioguanine; Vincristine | 1993 |
[Lipid derivatives of sarcolysin, methotrexate and rubomycin].
Topics: Daunorubicin; Lipids; Magnetic Resonance Spectroscopy; Mass Spectrometry; Melphalan; Methotrexate; Spectrophotometry, Ultraviolet | 1996 |
In vitro drug sensitivity testing can predict induction failure and early relapse of childhood acute lymphoblastic leukemia.
Topics: Aclarubicin; Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bleomycin; Bone Marrow; Cell Survival; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Disease-Free Survival; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Etoposide; Follow-Up Studies; Humans; Infant; Infant, Newborn; Life Tables; Melphalan; Methotrexate; Mitomycin; Mitoxantrone; Neoplastic Stem Cells; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Recurrence; Remission Induction; Tumor Cells, Cultured; Vincristine | 1997 |
[A case of the successful treatment of acute plasmablastic leukemia].
Topics: Acute Disease; Adult; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Daunorubicin; Diuretics; Drug Therapy, Combination; Female; Humans; Leukemia, Plasma Cell; Melphalan; Prednisolone; Time Factors; Vasodilator Agents; Vincristine | 1997 |
[A second allogeneic transplantation with a mild conditioning regimen in a patient with a posttransplantation relapse of lymphoblastic lymphoma after achieving aplasia with Daunoxome and alkeran].
Topics: Adult; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Bone Marrow Transplantation; Combined Modality Therapy; Daunorubicin; Humans; Liposomes; Male; Melphalan; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Retreatment; Time Factors; Transplantation Conditioning; Transplantation, Homologous | 2000 |
Abrogation of G(2)/M-phase block enhances the cytotoxicity of daunorubicin, melphalan and cisplatin in TP53 mutant human tumor cells.
Topics: Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cell Count; Cell Cycle; Cell Survival; Cisplatin; Daunorubicin; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Flow Cytometry; G2 Phase; Humans; Melanoma; Melphalan; Mitosis; Mutation; Pentoxifylline; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2000 |
High-dose consolidation chemotherapy with Idarubicin and alkylating agents following induction with gemcitabine-epirubicin-paclitaxel in metastatic breast cancer: a dose finding study.
Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Daunorubicin; Deoxycytidine; Disease Progression; Disease-Free Survival; Dose-Response Relationship, Drug; Epirubicin; Female; Humans; Idarubicin; Melphalan; Middle Aged; Neoplasm Metastasis; Paclitaxel; Remission Induction; Taxoids; Thiotepa; Time Factors; Transplantation Conditioning; Treatment Outcome | 2003 |
Inhibition of thioredoxin reductase but not of glutathione reductase by the major classes of alkylating and platinum-containing anticancer compounds.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antioxidants; Binding Sites; Busulfan; Chlorambucil; Cisplatin; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Drug Screening Assays, Antitumor; Glutathione Reductase; Melphalan; Organoplatinum Compounds; Oxaliplatin; Rats; Spectrophotometry; Substrate Specificity; Thioredoxin-Disulfide Reductase; Time Factors | 2005 |
Chemopotentiating effects of a novel NAD biosynthesis inhibitor, FK866, in combination with antineoplastic agents.
Topics: Acrylamides; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Cell Death; Cell Line, Tumor; Cell Survival; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Combinations; Humans; K562 Cells; Leukemia, Myeloid, Acute; Melphalan; Methylnitronitrosoguanidine; Monocytes; NAD; Piperidines | 2006 |
Differential effects of novel tumour-derived p53 mutations on the transformation of NIH-3T3 cells.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Blotting, Western; Cell Cycle; Cell Division; Cell Survival; Cell Transformation, Neoplastic; Cisplatin; Daunorubicin; DNA, Complementary; Immunohistochemistry; Kinetics; Melphalan; Mice; Models, Molecular; Mutation; NIH 3T3 Cells; Protein Conformation; Transfection; Tumor Suppressor Protein p53 | 2008 |
In vitro and in vivo anti-leukemic activity of the peptidase-potentiated alkylator melflufen in acute myeloid leukemia.
Topics: Animals; Antigens, CD34; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Synergism; Female; HL-60 Cells; Humans; Inhibitory Concentration 50; Leukemia, Myeloid, Acute; Male; Melphalan; Mice, SCID; Middle Aged; Neoplastic Stem Cells; Phenylalanine; Time Factors; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2017 |