Page last updated: 2024-08-23

daunorubicin and formaldehyde

daunorubicin has been researched along with formaldehyde in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (75.00)18.2507
2000's2 (16.67)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Gao, YG; Li, YK; Liaw, YC; Wang, AH1
Gao, YG; Li, YK; Liaw, YC; van Boom, JH; van der Marel, GA; Wang, AH1
Rutherford, AV; Willingham, MC1
Gao, YG; van Boom, JH; van der Marel, GA; Wang, AH; Zhang, H1
Gaudiano, G; Koch, TH; Resing, K; Taatjes, DJ1
Fenick, DJ; Koch, TH; Taatjes, DJ2
Gaudiano, G; Koch, TH; Taatjes, DJ1
Dutta, R; Gao, YG; Priebe, W; Wang, AH1
Bierbaum, VM; Burke, PJ; Fenick, DJ; Kato, S; Koch, TH; Taatjes, DJ1
Anizon, F; Bailly, C; Chaires, JB; Goossens, JF; Laine, W; Prudhomme, M; Ren, J1

Other Studies

12 other study(ies) available for daunorubicin and formaldehyde

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Formaldehyde cross-links daunorubicin and DNA efficiently: HPLC and X-ray diffraction studies.
    Biochemistry, 1991, Apr-23, Volume: 30, Issue:16

    Topics: Base Sequence; Chromatography, High Pressure Liquid; Daunorubicin; DNA; Formaldehyde; Models, Molecular; Molecular Conformation; Nucleic Acid Conformation; Oligodeoxyribonucleotides; X-Ray Diffraction

1991
Facile formation of a crosslinked adduct between DNA and the daunorubicin derivative MAR70 mediated by formaldehyde: molecular structure of the MAR70-d(CGTnACG) covalent adduct.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, Jun-01, Volume: 88, Issue:11

    Topics: Antineoplastic Agents; Base Sequence; Cross-Linking Reagents; Daunorubicin; DNA; Formaldehyde; Models, Molecular; Molecular Conformation; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Structure-Activity Relationship

1991
Ultrastructural localization of daunomycin in multidrug-resistant cultured cells with modulation of the multidrug transporter.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1993, Volume: 41, Issue:10

    Topics: 3T3 Cells; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Cell Nucleus; Daunorubicin; Drug Resistance; Endoplasmic Reticulum; Fixatives; Formaldehyde; Glutaral; Humans; Lysosomes; Membrane Glycoproteins; Mice; Microscopy, Electron; Microscopy, Fluorescence; Nuclear Envelope; Photochemistry; Verapamil

1993
Simultaneous incorporations of two anticancer drugs into DNA. The structures of formaldehyde-cross-linked adducts of daunorubicin-d(CG(araC)GCG) and doxorubicin-d(CA(araC)GTG) complexes at high resolution.
    The Journal of biological chemistry, 1993, May-15, Volume: 268, Issue:14

    Topics: Base Sequence; Cross-Linking Reagents; Cytarabine; Daunorubicin; DNA; Doxorubicin; Formaldehyde; Models, Molecular; Molecular Structure; Nucleic Acid Conformation; Oligodeoxyribonucleotides; X-Ray Diffraction

1993
Alkylation of DNA by the anthracycline, antitumor drugs adriamycin and daunomycin.
    Journal of medicinal chemistry, 1996, Oct-11, Volume: 39, Issue:21

    Topics: Alkylation; Animals; Antibiotics, Antineoplastic; Chromatography, High Pressure Liquid; Daunorubicin; Dithiothreitol; DNA; Doxorubicin; Formaldehyde; Humans; Hydrogen Peroxide; Mass Spectrometry; Oxidants; Spectrophotometry, Ultraviolet; Sulfhydryl Reagents

1996
Doxoform and Daunoform: anthracycline-formaldehyde conjugates toxic to resistant tumor cells.
    Journal of medicinal chemistry, 1997, Aug-01, Volume: 40, Issue:16

    Topics: Alkylation; Catalysis; Chromatography, High Pressure Liquid; Daunorubicin; Dimerization; DNA; Doxorubicin; Drug Resistance, Neoplasm; Formaldehyde; Humans; Hydrolysis; Mass Spectrometry; Models, Chemical; Oxazoles; Tumor Cells, Cultured

1997
Production of formaldehyde and DNA-adriamycin or DNA-daunomycin adducts, initiated through redox chemistry of dithiothreitol/iron, xanthine oxidase/NADH/iron, or glutathione/iron.
    Chemical research in toxicology, 1997, Volume: 10, Issue:9

    Topics: Anaerobiosis; Antibiotics, Antineoplastic; Buffers; Chromatography, High Pressure Liquid; Daunorubicin; Dithiothreitol; DNA Adducts; Doxorubicin; Formaldehyde; Glutathione; Hydrogen Peroxide; Indicators and Reagents; Iron; NAD; Oxidation-Reduction; Xanthine Oxidase

1997
Binding of the modified daunorubicin WP401 adjacent to a T-G base pair induces the reverse Watson-Crick conformation: crystal structures of the WP401-TGGCCG and WP401-CGG[br5C]CG complexes.
    Nucleic acids research, 1998, Jun-15, Volume: 26, Issue:12

    Topics: Antibiotics, Antineoplastic; Base Composition; Cross-Linking Reagents; Crystallography, X-Ray; Daunorubicin; DNA; Formaldehyde; Models, Molecular; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; Oligodeoxyribonucleotides

1998
Nuclear targeting and nuclear retention of anthracycline-formaldehyde conjugates implicates DNA covalent bonding in the cytotoxic mechanism of anthracyclines.
    Chemical research in toxicology, 1999, Volume: 12, Issue:7

    Topics: Alkylation; Antineoplastic Agents; Cell Nucleus; Daunorubicin; DNA, Neoplasm; Doxorubicin; Epirubicin; Formaldehyde; Humans; RNA, Neoplasm; Spectrometry, Fluorescence; Tumor Cells, Cultured

1999
Mass spectrometric measurement of formaldehyde generated in breast cancer cells upon treatment with anthracycline antitumor drugs.
    Chemical research in toxicology, 2000, Volume: 13, Issue:6

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Cross-Linking Reagents; Daunorubicin; Doxorubicin; Female; Formaldehyde; Humans; Mass Spectrometry; Tumor Cells, Cultured

2000
Formaldehyde-induced alkylation of a 2'-aminoglucose rebeccamycin derivative to both A.T and G.C base pairs in DNA.
    Journal of medicinal chemistry, 2000, Nov-30, Volume: 43, Issue:24

    Topics: Alkylation; Aminoglycosides; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Carbazoles; Cross-Linking Reagents; Daunorubicin; DNA; Electrophoresis, Polyacrylamide Gel; Fluorescence; Formaldehyde; Indoles; Nucleic Acid Denaturation

2000