daunorubicin has been researched along with epirubicin in 98 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 25 (25.51) | 18.7374 |
1990's | 30 (30.61) | 18.2507 |
2000's | 23 (23.47) | 29.6817 |
2010's | 14 (14.29) | 24.3611 |
2020's | 6 (6.12) | 2.80 |
Authors | Studies |
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Arcamone, F; Bargiotii, A; Casazza, AM; Cassinelli, G; Dasdia, T; Di Marco, A; Hanessian, S; Necco, A; Redaelli, S; Reggiani, P; Supino, R | 1 |
Cole, SP; Deeley, RG; Grant, CE; Hipfner, DR; Loe, DW; Stride, BD | 1 |
Fenick, DJ; Koch, TH; Taatjes, DJ | 2 |
Dantzig, AH; Godinot, N; Iversen, PW; Perry, WL; Tabas, L; Williams, DC; Xia, X | 1 |
Cole, SP; Deeley, RG; Grant, CE; Nunoya, K; Zhang, D | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Benfenati, E; Raska, I; Toropov, AA; Toropova, AP | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Barthwal, R; Pandav, K; Raje, S | 1 |
Belov, L; Davey, MW; Davey, RA; Kidman, AD; Marks, DC | 1 |
Alfonso, A; Arnaez, E; Botana, LM; Louzao, MC; Vieytes, MR | 1 |
Lewis, W; Papoian, T | 1 |
Brunet, C; Cazin, JC; Cazin, M; Dine, T; Goudaliez, F; Gressier, B; Luyckx, M; Mallevais, ML; Toraub, I | 1 |
Ames, MM; Kuffel, MJ; Reid, JM | 1 |
Araki, Y; Gomita, Y; Shinozawa, S | 1 |
Irth, H; Reinhoud, NJ; Tjaden, UR; van der Greef, J | 1 |
Carlhant, D; Glaise, D; Guillouzo, A; Kernaleguen, D; Le Bot, MA; Ratanasavanh, D; Riche, C | 1 |
Cairo, MS; Sender, L; Toy, C; van de Ven, C | 1 |
Irwin, WJ; Scott, DK; Wood, MJ | 2 |
Amadori, D; Dollbaum, C; Hackett, AJ; Hiller, A; Lippman, M; Mayall, B; Smith, HS; Swain, S; Volpi, A; Zoli, W | 1 |
Cole, SP; Gerlach, JH; Mirski, SE | 1 |
Vile, GF; Winterbourn, CC | 1 |
Capalbo, MI; Stipani, I; Zara, V | 1 |
Robert, J; Schott, B | 1 |
Grankvist, K; Henriksson, R; Stendahl, U | 1 |
Cheng, E; Chuang, YJ; Niedzwiecki, D; Sordillo, PP; Sternberg, CN | 1 |
Chen, ZM; Colombo, T; Conforti, L; Fiedorowicz, RJ; Grazia Donelli, M; Latini, R; Marchi, S; Paolini, A; Riva, E; Zuanetti, G | 1 |
Raymond, V; Young, CW | 1 |
Clagett-Carr, K; Leyland-Jones, B; Russo, M; Sarosy, G; Weiss, RB | 1 |
Alcan, KE; Benua, RS; Graham, MC; Oliver, FH; Palestro, C; Robeson, W | 1 |
Falkson, G; Iturralde, MP; Vorobiof, DA | 1 |
Airiau, J; Bégué, JM; Guillouzo, A; Kernaleguen, D; Le Bot, MA; Ratanasavanh, D; Riché, C; Robert, J | 1 |
Robert, J | 1 |
Bonadonna, G; Bonfante, V; Brambilla, C; Crippa, F; Ferrari, L; Rossi, A; Valagussa, P; Villani, F | 1 |
Aoki, N; Imai, Y; Murohashi, I; Nara, N; Tanikawa, S; Yamashita, Y | 1 |
Berens, ME; Modest, EJ; Saito, T; Welander, CE | 1 |
Ganzina, F; Hurteloup, P | 1 |
Arcamone, F | 2 |
Ogawa, M | 1 |
Jasmin, C; Maral, R; Marzin, D; Mathe, G | 1 |
Horton, D; Priebe, W; Varela, O | 1 |
Bramwell, V; Bruntsch, U; Cavalli, F; Decoster, G; Dombernowsky, P; Høst, H; Renard, G; Rozencweig, M; ten Bokkel Huinink, W; Van Glabbeke, M | 1 |
Arcamone, F; Menozzi, M; Valentini, L; Vannini, E | 1 |
Hu, X; Pan, Q; Zheng, S | 1 |
Chen, WY; Hu, X | 2 |
Cowman, A; Hu, XF; Kantharidis, P; Parkin, JD; Slater, A; Wall, DM; Zalcberg, JR | 1 |
Konopa, J; Skladanowski, A | 1 |
Dorn, A; Graf, N; Pees, HW | 1 |
Bast, A; Boven, E; de Jong, J; Kuiper, CM; van der Vijgh, WJ | 1 |
Clausen, OP; De Angelis, P; Lehne, G; Rugstad, HE | 2 |
Yamori, T | 1 |
Horikawa, K; Okada, Y; Sano, M | 1 |
Baginski, M; Briggs, JM; Fogolari, F | 1 |
deSilva, M; El-Osta, A; Hu, XF; Kantharidis, P; Nadalin, G; Parkin, JD; Slater, A; Wall, DM; Zalcberg, JR | 1 |
Barbara, C; Bocci, G; Danesi, R; Del Tacca, M; Di Paolo, A; Fogli, S; Innocenti, F | 1 |
Harrington, DJ; Koch, TH; Podell, ER; Taatjes, DJ | 1 |
Lankelma, J; Westerhoff, HV; Wielinga, PR | 1 |
Garnier-Suillerot, A; Marbeuf-Gueye, C; Quidu, P; Salerno, M | 1 |
Aita, P; Bearz, A; Boiocchi, M; Colussi, AM; Corona, G; Crivellari, D; Robieux, I; Sorio, R; Stocco, F; Toffoli, G | 1 |
Brunetti, L; Michelotto, B; Orlando, G; Ragazzoni, E; Recinella, L; Vacca, M | 1 |
Davey, M; Davey, R; Locke, V | 1 |
Gatto, B; Moro, S; Palumbo, M; Sissi, C; Zagotto, G | 1 |
Bengala, C; Biadi, O; Conte, PF; Danesi, R; Del Tacca, M; Donati, S; Favre, C; Fogli, S; Guarneri, V; Innocenti, F; Mariani, M; Pazzagli, I | 1 |
McHowat, J; Sarvazyan, N; Swift, L | 1 |
Damon, L; Demirer, T; Derigs, G; Ferrante, P; Kröger, N; Rosti, G; Wandt, H; Zander, AR | 1 |
Chiam, AS; Huxham, LA; Kyle, AH; Minchinton, AI; Sim, DH | 1 |
Miura, T; Muraoka, S | 1 |
Seiter, K | 1 |
Fuerhacker, M; Lenz, K; Mader, RM; Mahnik, SN; Weissenbacher, N | 1 |
Chan, GC; Cheuk, DK; Chiang, AK; Ha, SY; Lau, YL; Shek, TW | 1 |
Lambert, WE; Maudens, KE; Wille, SM | 1 |
Hu, XF; Li, J; Vandervalk, S; Xing, PX; Yang, E | 1 |
Bárdi, E; Bobok, I; Kappelmayer, J; Kiss, C; V Oláh, A | 1 |
Richardson, DR; Sutak, R; Xu, X | 1 |
Agrawal, P; Barthwal, R; Govil, G; Jagannathan, NR; Sharma, U; Tripathi, AN | 1 |
Hao, Z; Weng, N; Xiao, B | 1 |
Lillquist, A; Lunte, CE; O'Connor, R; Pasas, SA; Regan, F; Smyth, MR; Whitaker, G | 1 |
Baubion, N; Buzyn, A; Decaudin, D; Delarue, R; Fourquet, A; Ghez, D; Hermine, O; Messas, E; Rubio, MT; Suarez, F; Varet, B; Willems, L | 1 |
Fujiwara, K; Matsunaga, H; Shin, M | 1 |
Bermingham, S; McMahon, GP; O'Connor, R; Regan, F | 1 |
Adam, E; Eksborg, S; Flaberg, E; Klein, E; Kozma, A; Markasz, L; Masszi, T; Miseta, A; Nagy, N; Otvos, R; Skribek, H; Szekely, L | 1 |
Firlej, A; Jelińska, A; Leśniewska, M; Oszczapowicz, I; Sobczak, A | 1 |
Ban, YH; Han, AR; Kim, BG; Kim, E; Kim, EJ; Lee, MK; Park, JW; Sohng, JK; Yoo, YJ; Yoon, YJ | 1 |
Bednarski, W; Dettlaff, K; Jelińska, A; Kaczmarek, A; Oszczapowicz, I; Paszel-Jaworska, A; Rybczyńska, M; Totoń, E | 1 |
Arshad, N; Nosheen, B; Nowsherwan, J; Perveen, F; Qureshi, R; Rafique, H; Sultan, A | 1 |
Bertrand, D; Bonnier, F; Byrne, HJ; Chourpa, I; Chtara, F; Makki, AA; Mohammed, E; Respaud, R; Tauber, C; Tfayli, A | 1 |
Han, J; Liu, M; Liu, T; Liu, Y; Pei, W; Sun, B; Wang, Q; Wu, Y; Zhao, Y | 1 |
Chybicka, K; Drobczyński, S; Frączkowska, K; Kaczorowska, A; Kałas, W; Kopaczyńska, M; Kraszewski, S; Lamperska, W; Masajada, J; Podbielska, H; Sobas, M; Tarkowski, R; Wróbel, T | 1 |
Bhatia, S; Borkhardt, A; Christianson, DW; Hansen, FK; Hauer, J; Kassack, MU; Osko, JD; Reßing, N; Schliehe-Diecks, J; Schöler, A; Skerhut, A; Sönnichsen, M | 1 |
Hepel, M; Herschkowitz, JI; Kurzątkowska, K; Pazos, MA | 1 |
Bonnabry, P; Fleury-Souverain, S; Guillarme, D; Maurin, J; Rudaz, S | 1 |
Bai, R; Chang, X; Li, L; Li, Y; Lin, R; Liu, N; Liu, X; Peng, X; Ruan, Y; Tang, R; Wang, X; Wen, S | 1 |
12 review(s) available for daunorubicin and epirubicin
Article | Year |
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DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Clinical assessment of the structure-activity relationship of anthracyclines and related synthetic derivatives.
Topics: Aclarubicin; Anthraquinones; Antibiotics, Antineoplastic; Breast Neoplasms; Carubicin; Cell Survival; Daunorubicin; Doxorubicin; Drug Evaluation; Epirubicin; Heart; Humans; Idarubicin; Leukemia; Menogaril; Mitoxantrone; Naphthacenes; Nogalamycin; Sarcoma; Structure-Activity Relationship | 1986 |
Anthracycline analogs: the past, present, and future.
Topics: Animals; Antibiotics, Antineoplastic; Cardiomyopathies; Clinical Trials as Topic; Daunorubicin; Doxorubicin; Epirubicin; Female; Guinea Pigs; Heart; Humans; Idarubicin; Male; Menogaril; Mice; Nogalamycin; Rabbits; Rats | 1986 |
[Pharmacokinetics of new anthracyclines].
Topics: Antibiotics, Antineoplastic; Daunorubicin; Doxorubicin; Epirubicin; Humans; Idarubicin | 1988 |
Clinical studies with new anthracyclines: epirubicin, idarubicin, esorubicin.
Topics: Antibiotics, Antineoplastic; Bone Marrow; Clinical Trials as Topic; Daunorubicin; Doxorubicin; Drug Evaluation; Epirubicin; Heart; Humans; Idarubicin; Neoplasms | 1986 |
[Current status of clinical results of new antitumor drugs].
Topics: Aminoacridines; Amsacrine; Anthracyclines; Anthraquinones; Antibiotics, Antineoplastic; Antineoplastic Agents; Aziridines; Benzoquinones; Carboplatin; Carubicin; Cisplatin; Daunorubicin; Doxorubicin; Eflornithine; Epirubicin; Humans; Idarubicin; Mitoxantrone; Naphthacenes; Neoplasms; Organoplatinum Compounds; Ornithine; Ribavirin | 1985 |
Anthracyclines: recent developments in their separation and quantitation.
Topics: Antibiotics, Antineoplastic; Chromatography, High Pressure Liquid; Daunorubicin; Doxorubicin; Electrophoresis, Capillary; Epirubicin; Idarubicin; Spectrophotometry, Ultraviolet | 2001 |
Secondary acute leukemia following mitoxantrone-based high-dose chemotherapy for primary breast cancer patients.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Epirubicin; Female; Humans; Incidence; Leukemia, Myeloid; Leukemia, Myelomonocytic, Acute; Leukemia, Promyelocytic, Acute; Leukemia, Radiation-Induced; Lymphatic Metastasis; Melphalan; Middle Aged; Mitoxantrone; Neoplasms, Second Primary; Paclitaxel; Peripheral Blood Stem Cell Transplantation; Radiotherapy, Adjuvant; Thiotepa; Transplantation Conditioning; Transplantation, Autologous | 2003 |
Toxicity of the topoisomerase II inhibitors.
Topics: Antineoplastic Agents; Cardiovascular Diseases; Daunorubicin; Doxorubicin; Enzyme Inhibitors; Epirubicin; Etoposide; Humans; Idarubicin; Leukemia; Middle Aged; Mitoxantrone; Mucositis; Podophyllotoxin; Teniposide; Topoisomerase II Inhibitors; Vascular Diseases | 2005 |
Parotid acinar cell carcinoma in a long-term survivor of childhood acute lymphoblastic leukemia.
Topics: Adenoma, Sweat Gland; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Carcinoma, Acinar Cell; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Epirubicin; Etoposide; Follow-Up Studies; Humans; Male; Mercaptopurine; Methotrexate; Neoplasms, Radiation-Induced; Neoplasms, Second Primary; Parotid Neoplasms; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Recurrence; Remission Induction; Survivors; Sweat Gland Neoplasms; Vincristine; Whole-Body Irradiation | 2008 |
Impact of column temperature and mobile phase components on selectivity of hydrophilic interaction chromatography (HILIC).
Topics: Arginine; Choline; Chromatography, Liquid; Daunorubicin; Epirubicin; Glycine; Hydrogen Bonding; Phase Transition; Silicon Dioxide; Solvents; Tandem Mass Spectrometry; Temperature; Water | 2008 |
The Role of Mitochondrial Quality Control in Anthracycline-Induced Cardiotoxicity: From Bench to Bedside.
Topics: Anthracyclines; Antibiotics, Antineoplastic; Calcium; Cardiotoxicity; Daunorubicin; Doxorubicin; Epirubicin; Humans; Idarubicin; Mitochondria; Mitochondrial Proteins; Myocytes, Cardiac; Reactive Oxygen Species | 2022 |
5 trial(s) available for daunorubicin and epirubicin
Article | Year |
---|---|
Anthracycline analogs: the past, present, and future.
Topics: Animals; Antibiotics, Antineoplastic; Cardiomyopathies; Clinical Trials as Topic; Daunorubicin; Doxorubicin; Epirubicin; Female; Guinea Pigs; Heart; Humans; Idarubicin; Male; Menogaril; Mice; Nogalamycin; Rabbits; Rats | 1986 |
Clinical studies with new anthracyclines: epirubicin, idarubicin, esorubicin.
Topics: Antibiotics, Antineoplastic; Bone Marrow; Clinical Trials as Topic; Daunorubicin; Doxorubicin; Drug Evaluation; Epirubicin; Heart; Humans; Idarubicin; Neoplasms | 1986 |
Randomized phase II trial of carminomycin versus 4'-epidoxorubicin in advanced breast cancer.
Topics: Adult; Aged; Alopecia; Breast Neoplasms; Carubicin; Daunorubicin; Doxorubicin; Drug Evaluation; Epirubicin; Female; Follow-Up Studies; Heart Diseases; Humans; Leukopenia; Middle Aged; Nausea; Neoplasm Metastasis; Random Allocation; Vomiting | 1984 |
An improved HPLC method for therapeutic drug monitoring of daunorubicin, idarubicin, doxorubicin, epirubicin, and their 13-dihydro metabolites in human plasma.
Topics: Antibiotics, Antineoplastic; Chromatography, High Pressure Liquid; Daunorubicin; Doxorubicin; Drug Monitoring; Epirubicin; Humans; Idarubicin; Linear Models; Molecular Structure; Reference Values; Reproducibility of Results; Sensitivity and Specificity | 1999 |
Dose-finding and pharmacologic study of chronic oral idarubicin therapy in metastatic breast cancer patients.
Topics: Administration, Oral; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Breast Neoplasms; Cyclophosphamide; Daunorubicin; Docetaxel; Dose-Response Relationship, Drug; Doxorubicin; Epirubicin; Female; Fluorouracil; Humans; Idarubicin; Maximum Tolerated Dose; Methotrexate; Middle Aged; Neoplasm Metastasis; Paclitaxel; Taxoids; Time Factors | 2000 |
83 other study(ies) available for daunorubicin and epirubicin
Article | Year |
---|---|
Stereocontrolled glycosidation of daunomycinone. Synthesis and biological evaluation of 6-hydroxy-L-arabino analogues of antitumor anthracyclines.
Topics: Animals; Anthraquinones; Antineoplastic Agents; Arabinose; Cells, Cultured; Daunorubicin; Doxorubicin; Embryo, Mammalian; HeLa Cells; In Vitro Techniques; Mice; Moloney murine leukemia virus; Nucleosides; Sarcoma 180 | 1976 |
Pharmacological characterization of the murine and human orthologs of multidrug-resistance protein in transfected human embryonic kidney cells.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; ATP-Binding Cassette Transporters; Cells, Cultured; Culture Techniques; Drug Resistance, Neoplasm; Embryo, Mammalian; Estradiol; Glutathione; Humans; Isomerism; Kidney; Leukotriene C4; Membranes; Mice; Multidrug Resistance-Associated Proteins; Phenotype; Transfection; Vincristine | 1997 |
Epidoxoform: a hydrolytically more stable anthracycline-formaldehyde conjugate toxic to resistant tumor cells.
Topics: Antibiotics, Antineoplastic; Cell Division; DNA Adducts; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Epirubicin; Humans; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Magnetic Resonance Spectroscopy; Mass Spectrometry; Oligonucleotides; Tumor Cells, Cultured | 1998 |
Cloning and functional characterization of the multidrug resistance-associated protein (MRP1/ABCC1) from the cynomolgus monkey.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Antibiotics, Antineoplastic; Cell Line, Transformed; Cloning, Molecular; Dogs; Drug Resistance, Multiple; Humans; Kidney; Leukotriene C4; Macaca fascicularis; Mice; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; RNA, Messenger; Sequence Homology, Amino Acid; Species Specificity; Transfection | 2003 |
Molecular cloning and pharmacological characterization of rat multidrug resistance protein 1 (mrp1).
Topics: Amino Acid Sequence; Animals; Carrier Proteins; Cell Line; Cloning, Molecular; DNA, Complementary; Doxorubicin; Embryo, Mammalian; Estradiol; Estradiol Congeners; Estrone; Gene Expression Regulation; Humans; Kidney; Leukotriene C4; Mice; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Mutagenesis, Site-Directed; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Amino Acid; Species Specificity; Substrate Specificity; Transfection; Tritium | 2003 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations.
Topics: Antineoplastic Agents; Models, Chemical; Octanols; Quantitative Structure-Activity Relationship; Water | 2010 |
Dual mode of binding of anti cancer drug epirubicin to G-quadruplex [d-(TTAGGGT)]
Topics: Antineoplastic Agents; Base Sequence; Circular Dichroism; DNA; Drug Design; Epirubicin; G-Quadruplexes; Hot Temperature; Humans; Molecular Structure; Nucleic Acid Conformation; Nucleic Acid Denaturation; Telomere | 2019 |
The MTT cell viability assay for cytotoxicity testing in multidrug-resistant human leukemic cells.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Survival; Coloring Agents; Daunorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Epirubicin; Humans; Membrane Glycoproteins; Tetrazolium Salts; Thiazoles; Trypan Blue; Verapamil; Vinblastine | 1992 |
Nonimmunological release of histamine from rat mast cells elicited by antineoplastic agents: effect of drug combinations.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Calcium; Dactinomycin; Daunorubicin; Doxorubicin; Epirubicin; Histamine Release; Mast Cells; p-Methoxy-N-methylphenethylamine; Peritoneal Cavity; Pleura; Rats; Rats, Sprague-Dawley | 1992 |
Anthracyclines selectively decrease alpha cardiac actin mRNA abundance in the rat heart.
Topics: Actin Cytoskeleton; Actins; Animals; Antibiotics, Antineoplastic; Daunorubicin; DNA; Doxorubicin; Electrophoresis, Agar Gel; Epirubicin; Female; Microscopy, Electron; Myocardium; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1992 |
Stability and compatibility of four anthracyclines: doxorubicin, epirubicin, daunorubicin and pirarubicin with PVC infusion bags.
Topics: Antibiotics, Antineoplastic; Chromatography, High Pressure Liquid; Daunorubicin; Doxorubicin; Drug Stability; Epirubicin; Infusion Pumps; Infusions, Intravenous; Polyvinyl Chloride; Solutions | 1992 |
Anthracyclines and their C-13 alcohol metabolites: growth inhibition and DNA damage following incubation with human tumor cells in culture.
Topics: Antibiotics, Antineoplastic; Cell Division; Daunorubicin; DNA Damage; DNA, Neoplasm; Doxorubicin; Epirubicin; Glioma; Humans; Idarubicin; Leukemia, Myeloid; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured | 1992 |
[Effects of anthracycline drugs (aclarubicin, daunorubicin, doxorubicin, epirubicin, pirarubicin) on mouse acute toxicity and rat liver microsomal lipid peroxidation].
Topics: Aclarubicin; Animals; Antibiotics, Antineoplastic; Body Weight; Daunorubicin; Doxorubicin; Epirubicin; Lipid Peroxidation; Male; Mice; Mice, Inbred ICR; Microsomes, Liver; Mitochondria, Liver; Rats; Rats, Inbred Strains | 1992 |
Bioanalysis of some anthracyclines in human plasma by capillary electrophoresis with laser-induced fluorescence detection.
Topics: Daunorubicin; Doxorubicin; Electrophoresis; Epirubicin; Humans; Lasers; Reproducibility of Results; Spectrometry, Fluorescence | 1992 |
Metabolism of doxorubicin, daunorubicin and epirubicin in human and rat hepatoma cells.
Topics: Animals; Biotransformation; Carcinoma, Hepatocellular; Chromatography, High Pressure Liquid; Daunorubicin; Doxorubicin; Epirubicin; Humans; Liver; Rats; Tumor Cells, Cultured | 1991 |
Effect of idarubicin and epirubicin on in vitro polymorphonuclear function: diminished superoxide radical formation compared to their parent compounds daunorubicin and doxorubicin.
Topics: Cyclosporins; Daunorubicin; Doxorubicin; Epirubicin; Free Radicals; Humans; Idarubicin; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Superoxides; Verapamil | 1990 |
Stability of doxorubicin, daunorubicin and epirubicin in plastic syringes and minibags.
Topics: Chromatography, High Pressure Liquid; Daunorubicin; Doxorubicin; Drug Stability; Drug Storage; Epirubicin; Infusions, Intravenous; Plastics; Syringes | 1990 |
Photodegradation of doxorubicin, daunorubicin and epirubicin measured by high-performance liquid chromatography.
Topics: Analysis of Variance; Chromatography, High Pressure Liquid; Daunorubicin; Doxorubicin; Drug Stability; Drug Storage; Epirubicin; Kinetics; Light; Photolysis; Solutions; Sunlight | 1990 |
Preliminary correlations of clinical outcome with in vitro chemosensitivity of second passage human breast cancer cells.
Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoma; Cell Survival; Cisplatin; Daunorubicin; Doxorubicin; Epirubicin; Humans; In Vitro Techniques; Prognosis; Tumor Cells, Cultured; Vinblastine | 1990 |
Multidrug resistance in a human small cell lung cancer cell line selected in adriamycin.
Topics: Animals; Antibodies, Monoclonal; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Small Cell; Cell Line; Colchicine; Daunorubicin; Doxorubicin; Drug Resistance; Enzyme-Linked Immunosorbent Assay; Epirubicin; Etoposide; Glycoproteins; Gramicidin; Humans; Immunosorbent Techniques; Isoxazoles; Lung Neoplasms; Menogaril; Mice; Mice, Inbred BALB C; Mitoxantrone; Nogalamycin; Phenotype; Vinblastine; Vincristine | 1987 |
Microsomal lipid peroxidation induced by adriamycin, epirubicin, daunorubicin and mitoxantrone: a comparative study.
Topics: Animals; beta Carotene; Carotenoids; Catalysis; Cytochrome c Group; Daunorubicin; Doxorubicin; Epirubicin; Ferritins; Iron; Lipid Peroxidation; Microsomes, Liver; Mitoxantrone; Oxidation-Reduction; Oxygen; Partial Pressure; Rats; Rats, Inbred Strains; Vitamin E | 1989 |
Effect of anthracycline antibiotics on the reconstituted mitochondrial tricarboxylate carrier.
Topics: Animals; Antibiotics, Antineoplastic; Carrier Proteins; Citrates; Daunorubicin; Doxorubicin; Epirubicin; Idarubicin; Kinetics; Mitochondria, Liver; Rats | 1989 |
Comparative activity of anthracycline 13-dihydrometabolites against rat glioblastoma cells in culture.
Topics: Animals; Antibiotics, Antineoplastic; Cell Division; Daunorubicin; DNA, Neoplasm; Doxorubicin; Drug Resistance; Epirubicin; Glioma; Rats; Tumor Cells, Cultured | 1989 |
Comparative study of demethoxydaunorubicin with other anthracyclines on generation of oxygen radicals and clonogenic survival of fibroblasts.
Topics: Animals; Antibiotics, Antineoplastic; Catalase; Cell Line; Cell Survival; Chelating Agents; Clone Cells; Cricetinae; Daunorubicin; Doxorubicin; Electrodes; Epirubicin; Fibroblasts; Free Radicals; Idarubicin; Oxygen; Superoxide Dismutase | 1989 |
Evaluation of new anticancer agents against human pancreatic carcinomas in nude mice.
Topics: Adult; Aged; Alkaloids; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Carcinoma, Intraductal, Noninfiltrating; Daunorubicin; Doxorubicin; Drug Evaluation; Epirubicin; Female; Humans; Male; Menogaril; Mice; Mice, Nude; Microtubules; Neoplasm Transplantation; Nogalamycin; Paclitaxel; Pancreatic Neoplasms; Random Allocation; Transplantation, Heterologous | 1987 |
Effects of three new anthracyclines and doxorubicin on the rat isolated heart.
Topics: Animals; Antibiotics, Antineoplastic; Daunorubicin; Doxorubicin; Epirubicin; Heart; Idarubicin; Male; Myocardial Contraction; Myocardium; Rats; Rats, Inbred Strains | 1987 |
Early detection of anthracycline-induced cardiotoxicity by stress radionuclide cineangiography in conjunction with Fourier amplitude and phase analysis.
Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Cardiomyopathy, Dilated; Daunorubicin; Doxorubicin; Electrocardiography; Epirubicin; Female; Fourier Analysis; Heart Failure; Humans; Male; Middle Aged; Physical Exertion; Radionuclide Imaging; Sodium Pertechnetate Tc 99m | 1985 |
Radionuclide angiographic monitoring in patients treated with potentially cardiotoxic cytostatic drugs.
Topics: Amsacrine; Antibiotics, Antineoplastic; Daunorubicin; Doxorubicin; Electrocardiography; Epirubicin; Female; Heart; Humans; Idarubicin; Male; Mitoxantrone; Prospective Studies; Radionuclide Angiography; Stroke Volume | 1988 |
Different cytotoxicity and metabolism of doxorubicin, daunorubicin, epirubicin, esorubicin and idarubicin in cultured human and rat hepatocytes.
Topics: Adolescent; Adult; Animals; Cells, Cultured; Daunorubicin; Doxorubicin; Epirubicin; Epithelium; Humans; Idarubicin; L-Lactate Dehydrogenase; Liver; Male; Rats; Rats, Inbred Strains; Species Specificity | 1988 |
New anthracycline analogs in advanced breast cancer.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Breast Neoplasms; Daunorubicin; Doxorubicin; Drug Evaluation; Epirubicin; Female; Humans; Idarubicin; Middle Aged; Naphthacenes | 1986 |
Effects on leukemic clonogenic cells in murine myeloid leukemia of 1-beta-D-arabinofuranosylcytosine and the anthracyclines adriamycin, daunomycin, aclacinomycin A, and 4'-epidoxorubicin.
Topics: Aclarubicin; Animals; Antibiotics, Antineoplastic; Clone Cells; Colony-Forming Units Assay; Cytarabine; Daunorubicin; Doxorubicin; Epirubicin; Kinetics; Leukemia, Myeloid, Acute; Mice; Naphthacenes | 1987 |
Antitumor activity of new anthracycline analogues in combination with interferon alfa.
Topics: Cell Line; Colony-Forming Units Assay; Daunorubicin; Doxorubicin; Drug Synergism; Epirubicin; Female; Humans; Idarubicin; Interferon Type I; Tumor Stem Cell Assay | 1987 |
Properties of antitumor anthracyclines and new developments in their application: Cain memorial award lecture.
Topics: Antibiotics, Antineoplastic; Cell Survival; Daunorubicin; Doxorubicin; Epirubicin; Humans; Idarubicin; Kinetics; Metabolic Clearance Rate; Naphthacenes; Solubility; Structure-Activity Relationship; Tissue Distribution | 1985 |
Mutagenicity of eight anthracycline derivatives in five strains of Salmonella typhimurium.
Topics: Aclarubicin; Antibiotics, Antineoplastic; Daunorubicin; Doxorubicin; Epirubicin; Mutagenicity Tests; Mutagens; Naphthacenes; Salmonella typhimurium | 1983 |
3'-Deamino-4'-epi-3'-hydroxy-daunorubicin and -doxorubicin. Synthesis and antitumor activity.
Topics: Animals; Daunorubicin; Doxorubicin; Epirubicin; Leukemia P388; Mice; Structure-Activity Relationship | 1984 |
[Adriamycin and its analogs].
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Chemical Phenomena; Chemistry; Daunorubicin; DNA, Neoplasm; Doxorubicin; Epirubicin; Humans; Idarubicin; Stereoisomerism | 1984 |
Self-association of doxorubicin and related compounds in aqueous solution.
Topics: Chemistry, Pharmaceutical; Daunorubicin; Doxorubicin; Epirubicin; Idarubicin; Solutions; Spectrophotometry | 1984 |
[Reduced intracellular drug accumulation related to overexpression of P-glycoprotein cannot explain the complete drug resistance in MDR cell variant K562/Dox].
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Daunorubicin; Doxorubicin; Drug Resistance, Multiple; Epirubicin; Humans; Leukemia, Erythroblastic, Acute; Tumor Cells, Cultured | 1995 |
Restoration of intracellular drug accumulation in MDR cell line K562r does not mean reversal of its drug resistance.
Topics: Antineoplastic Combined Chemotherapy Protocols; Daunorubicin; Doxorubicin; Drug Resistance, Multiple; Epirubicin; Humans; Leukemia, Erythroblastic, Acute; Tumor Cells, Cultured | 1994 |
Rapid up-regulation of mdr1 expression by anthracyclines in a classical multidrug-resistant cell line.
Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Northern; Daunorubicin; Doxorubicin; Drug Resistance, Multiple; Epirubicin; Flow Cytometry; Gene Expression Regulation, Leukemic; Humans; Leukemia-Lymphoma, Adult T-Cell; RNA, Messenger; Tumor Cells, Cultured; Up-Regulation; Vinblastine; Vincristine | 1995 |
[Intracellular accumulation, retention, and distribution of anthracyclines in a multidrug-resistant variant K562r].
Topics: Antibiotics, Antineoplastic; Cell Nucleus; Chromatography, High Pressure Liquid; Cytoplasm; Daunorubicin; Doxorubicin; Drug Resistance; Epirubicin; Humans; Leukemia, Erythroblastic, Acute; Tumor Cells, Cultured; Verapamil | 1994 |
Interstrand DNA crosslinking induced by anthracyclines in tumour cells.
Topics: Antibiotics, Antineoplastic; Biotransformation; Cell Death; Cross-Linking Reagents; Daunorubicin; DNA; Epirubicin; HeLa Cells; Humans; Kinetics | 1994 |
[Intracellular measurement of anthracyclines with flow cytometry].
Topics: Aclarubicin; Antibiotics, Antineoplastic; Cells, Cultured; Daunorubicin; Doxorubicin; Epirubicin; Flow Cytometry; Humans; Leukocytes; Mitoxantrone | 1993 |
Relationship between the tumour tissue pharmacokinetics and the antiproliferative effects of anthracyclines and their metabolites.
Topics: Animals; Antibiotics, Antineoplastic; Cell Division; Daunorubicin; Doxorubicin; Epirubicin; Female; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Ovarian Neoplasms; Transplantation, Heterologous; Tumor Cells, Cultured | 1996 |
Human hepatoma cells rich in P-glycoprotein are sensitive to aclarubicin and resistant to three other anthracyclines.
Topics: Aclarubicin; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Hepatocellular; Cell Division; Cell Membrane; Daunorubicin; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Epirubicin; Humans; Liver Neoplasms; Microscopy, Confocal; Tumor Cells, Cultured | 1996 |
[A human cell line panel for screening anti-cancer drugs].
Topics: Animals; Antibiotics, Antineoplastic; Daunorubicin; Doxorubicin; Drug Screening Assays, Antitumor; Epirubicin; Humans; Mice; Software; Tumor Cells, Cultured | 1997 |
[Echocardiographic evaluation of cardiotoxicity induced by anthracycline therapy].
Topics: Aclarubicin; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Breast Neoplasms; Daunorubicin; Doxorubicin; Echocardiography; Epirubicin; Female; Heart; Hematologic Diseases; Humans; Male; Middle Aged; Mitoxantrone; Radionuclide Imaging; Stroke Volume | 1997 |
Electrostatic and non-electrostatic contributions to the binding free energies of anthracycline antibiotics to DNA.
Topics: Antibiotics, Antineoplastic; Daunorubicin; DNA; Doxorubicin; Epirubicin; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Naphthacenes; Nucleic Acid Conformation; Salts; Thermodynamics | 1997 |
Differential resistance to anthracyclines in P-glycoprotein-expressing human hepatoma cells.
Topics: Aclarubicin; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Hepatocellular; Cyclosporins; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Epirubicin; Humans; Liver Neoplasms; Tumor Cells, Cultured | 1998 |
Altered methylation of the human MDR1 promoter is associated with acquired multidrug resistance.
Topics: Antimetabolites, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azacitidine; Blotting, Southern; Daunorubicin; Decitabine; Dinucleoside Phosphates; DNA Methylation; Drug Resistance, Multiple; Epirubicin; Exons; Humans; Introns; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, T-Cell; Promoter Regions, Genetic; Restriction Mapping; Transcription, Genetic; Tumor Cells, Cultured; Verapamil | 1997 |
Nuclear targeting and nuclear retention of anthracycline-formaldehyde conjugates implicates DNA covalent bonding in the cytotoxic mechanism of anthracyclines.
Topics: Alkylation; Antineoplastic Agents; Cell Nucleus; Daunorubicin; DNA, Neoplasm; Doxorubicin; Epirubicin; Formaldehyde; Humans; RNA, Neoplasm; Spectrometry, Fluorescence; Tumor Cells, Cultured | 1999 |
Crystal structure of epidoxorubicin-formaldehyde virtual crosslink of DNA and evidence for its formation in human breast-cancer cells.
Topics: Antineoplastic Agents; Breast Neoplasms; Cross-Linking Reagents; Crystallography, X-Ray; Daunorubicin; DNA Adducts; DNA, Neoplasm; Epirubicin; Humans; Intercalating Agents; Nucleic Acid Conformation; Oligonucleotides; Tissue Distribution; Tumor Cells, Cultured | 1999 |
The relative importance of passive and P-glycoprotein mediated anthracycline efflux from multidrug-resistant cells.
Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Biological Transport, Active; Cell Compartmentation; Cell Line; Cell Membrane Permeability; Daunorubicin; Digitonin; Doxorubicin; Drug Resistance, Multiple; Epirubicin; Humans; Idarubicin; Kinetics; Verapamil | 2000 |
Inhibition of the P-glycoprotein- and multidrug resistance protein-mediated efflux of anthracyclines and calceinacetoxymethyl ester by PAK-104P.
Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Cyclic P-Oxides; Daunorubicin; Depression, Chemical; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Epirubicin; Fluoresceins; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Nicotinic Acids; Tumor Cells, Cultured | 2000 |
A possible prolactin-related adverse effect of certain antineoplastic anthracyclines.
Topics: Animals; Antibiotics, Antineoplastic; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Epirubicin; Male; Prolactin; Rats; Rats, Wistar | 2000 |
Paclitaxel sensitization of multidrug-resistant cells to chemotherapy is independent of the cell cycle.
Topics: Amsacrine; Antineoplastic Agents; Camptothecin; Carcinoma, Small Cell; Cell Cycle; Cell Survival; Chlorambucil; Cisplatin; Daunorubicin; Drug Resistance, Multiple; Epirubicin; Genistein; Humans; Lung Neoplasms; Paclitaxel; Tumor Cells, Cultured; Vinblastine; Vinorelbine | 2001 |
High-dose consolidation chemotherapy with Idarubicin and alkylating agents following induction with gemcitabine-epirubicin-paclitaxel in metastatic breast cancer: a dose finding study.
Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Daunorubicin; Deoxycytidine; Disease Progression; Disease-Free Survival; Dose-Response Relationship, Drug; Epirubicin; Female; Humans; Idarubicin; Melphalan; Middle Aged; Neoplasm Metastasis; Paclitaxel; Remission Induction; Taxoids; Thiotepa; Time Factors; Transplantation Conditioning; Treatment Outcome | 2003 |
Inhibition of membrane-associated calcium-independent phospholipase A2 as a potential culprit of anthracycline cardiotoxicity.
Topics: Animals; Anthracyclines; Antibiotics, Antineoplastic; Cardiomyopathies; Cells, Cultured; Daunorubicin; Doxorubicin; Epirubicin; Group VI Phospholipases A2; Heart Ventricles; Idarubicin; Myocytes, Cardiac; Oxidative Stress; Phospholipases A; Phospholipases A2; Rats; Rats, Sprague-Dawley | 2003 |
Direct assessment of drug penetration into tissue using a novel application of three-dimensional cell culture.
Topics: Anthracyclines; Antibiotics, Antineoplastic; Colorectal Neoplasms; Daunorubicin; Doxorubicin; Epirubicin; HCT116 Cells; Humans; Hydrogen-Ion Concentration; Kinetics; Mitoxantrone; Spectrometry, Fluorescence; Tumor Cells, Cultured | 2004 |
Thiol oxidation induced by oxidative action of adriamycin.
Topics: Aclarubicin; Antibiotics, Antineoplastic; Benzoquinones; Creatine Kinase; Daunorubicin; Doxorubicin; Electron Spin Resonance Spectroscopy; Epirubicin; Free Radicals; Glutathione; Horseradish Peroxidase; Hydrogen Peroxide; Hypoxanthine; Idarubicin; Oxidation-Reduction; Sulfhydryl Compounds; Xanthine Oxidase | 2004 |
Fate of 5-fluorouracil, doxorubicin, epirubicin, and daunorubicin in hospital wastewater and their elimination by activated sludge and treatment in a membrane-bio-reactor system.
Topics: Bioreactors; Daunorubicin; Doxorubicin; Epirubicin; Fluorouracil; Hospitals; Medical Waste Disposal; Molecular Structure; Pharmaceutical Preparations; Reproducibility of Results; Sewage; Waste Disposal, Fluid; Water Purification | 2007 |
Traces of phosgene in chloroform: consequences for extraction of anthracyclines.
Topics: Amines; Anthracyclines; Chloroform; Chromatography, Liquid; Daunorubicin; Doxorubicin; Epirubicin; Ethanol; Idarubicin; Molecular Structure; Phosgene; Reproducibility of Results; Solvents; Spectrometry, Fluorescence | 2007 |
Anti-Cripto Mab inhibit tumour growth and overcome MDR in a human leukaemia MDR cell line by inhibition of Akt and activation of JNK/SAPK and bad death pathways.
Topics: Animals; Antibodies, Monoclonal; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; bcl-Associated Death Protein; bcl-X Protein; Caspase 9; Cell Growth Processes; Cell Line, Tumor; Cytarabine; Daunorubicin; Drug Synergism; Enzyme Activation; Epirubicin; Female; Humans; Intercellular Signaling Peptides and Proteins; Leukemia; MAP Kinase Kinase 4; Mice; Mice, SCID; Mitogen-Activated Protein Kinases; Oncogene Protein v-akt; Proto-Oncogene Proteins c-bcl-2 | 2007 |
Anthracycline antibiotics induce acute renal tubular toxicity in children with cancer.
Topics: Acetylglucosaminidase; Adolescent; Adult; Albuminuria; Anthracyclines; Antibiotics, Antineoplastic; Antineoplastic Agents; Child; Child, Preschool; Creatinine; Daunorubicin; Doxorubicin; Epirubicin; Female; Humans; Idarubicin; Infant; Kidney Diseases; Kidney Tubules, Proximal; Lymphoma, Non-Hodgkin; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Razoxane; Retrospective Studies | 2007 |
Iron chelation by clinically relevant anthracyclines: alteration in expression of iron-regulated genes and atypical changes in intracellular iron distribution and trafficking.
Topics: Animals; Anthracyclines; Antibiotics, Antineoplastic; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Cell Survival; Daunorubicin; Deferoxamine; Dose-Response Relationship, Drug; Doxorubicin; Embryo, Mammalian; Epirubicin; Fibroblasts; Gene Expression Regulation; Humans; Intracellular Signaling Peptides and Proteins; Iron; Iron Chelating Agents; Kinetics; Mice; Mice, Knockout; Molecular Structure; Myocytes, Cardiac; Protein Binding; Protein Transport; Receptors, Transferrin; RNA, Messenger; Siderophores | 2008 |
Structural elucidation of 4'-epiadriamycin by nuclear magnetic resonance spectroscopy and comparison with adriamycin and daunomycin using quantum mechanical and restrained molecular dynamics approach.
Topics: Daunorubicin; Doxorubicin; Epirubicin; Magnetic Resonance Spectroscopy; Molecular Structure; Quantum Theory | 2008 |
CE-LIF method for the separation of anthracyclines: application to protein binding analysis in plasma using ultrafiltration.
Topics: Anthracyclines; Antibiotics, Antineoplastic; Antineoplastic Agents; Borates; Daunorubicin; Doxorubicin; Electrophoresis, Capillary; Epirubicin; Humans; Methanol; Models, Chemical; Protein Binding; Reproducibility of Results; Spectrometry, Fluorescence; Ultrafiltration | 2008 |
[High risk of cardiac dysfunction after treatment of secondary acute myeloid leukemia following chemotherapy and radiotherapy for breast cancer].
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Daunorubicin; Epirubicin; Female; Fluorouracil; Heart Diseases; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Middle Aged; Neoplasms, Second Primary; Remission Induction; Stroke Volume | 2010 |
Differences in accumulation of anthracyclines daunorubicin, doxorubicin and epirubicin in rat tissues revealed by immunocytochemistry.
Topics: Animals; Anthracyclines; Antineoplastic Agents; Daunorubicin; Doxorubicin; Epirubicin; Immunohistochemistry; Kidney Tubules, Proximal; Male; Rats; Rats, Wistar | 2010 |
Simultaneous determination of anthracyclines and taxanes in human serum using online sample extraction coupled to high performance liquid chromatography with UV detection.
Topics: Anthracyclines; Antineoplastic Agents; Blood Proteins; Calibration; Chemistry, Pharmaceutical; Chromatography; Chromatography, High Pressure Liquid; Daunorubicin; Docetaxel; Doxorubicin; Epirubicin; Humans; Paclitaxel; Sensitivity and Specificity; Taxoids | 2010 |
Chronic lymphoid leukemia cells are highly sensitive to the combination of prednisolone and daunorubicin, but much less to doxorubicin or epirubicin.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Cluster Analysis; Daunorubicin; Doxorubicin; Epirubicin; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Prednisolone | 2010 |
Stability of epidoxorubicin in solid state.
Topics: Algorithms; Antibiotics, Antineoplastic; Chromatography, High Pressure Liquid; Daunorubicin; Doxorubicin; Drug Stability; Epirubicin; Hot Temperature; Humidity; Kinetics; Powders; Technology, Pharmaceutical; Thermodynamics | 2011 |
Development of a Streptomyces venezuelae-based combinatorial biosynthetic system for the production of glycosylated derivatives of doxorubicin and its biosynthetic intermediates.
Topics: Anthracyclines; Daunorubicin; Doxorubicin; Epirubicin; Genetic Engineering; Glycosylation; Glycosyltransferases; Multigene Family; Plasmids; Streptomyces | 2011 |
Increased proapoptotic activity of electron beam irradiated doxorubicin and epirubicin in multidrug-resistant human leukemic cells.
Topics: Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Blotting, Western; Caspases; Cell Line, Tumor; Daunorubicin; Doxorubicin; Drug Resistance, Multiple; Electron Spin Resonance Spectroscopy; Electrons; Epirubicin; Free Radicals; Humans; NF-kappa B; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Suppressor Protein p53 | 2016 |
Electrochemical, spectroscopic and theoretical monitoring of anthracyclines' interactions with DNA and ascorbic acid by adopting two routes: Cancer cell line studies.
Topics: Antibiotics, Antineoplastic; Antioxidants; Ascorbic Acid; Cardiotoxicity; Cell Line, Tumor; Cell Proliferation; Daunorubicin; DNA; Doxorubicin; Drug Interactions; Epirubicin; Humans; Hydrogen-Ion Concentration; Molecular Docking Simulation; Neoplasms | 2018 |
COMMON STEM. -rubicin.
Topics: Anthracyclines; Daunorubicin; Doxorubicin; Epirubicin; Humans; Idarubicin; Terminology as Topic | 2016 |
Qualitative and quantitative analysis of therapeutic solutions using Raman and infrared spectroscopy.
Topics: Antibiotics, Antineoplastic; Daunorubicin; Discriminant Analysis; Doxorubicin; Epirubicin; Principal Component Analysis; Solutions; Spectrophotometry, Infrared; Spectrum Analysis, Raman | 2019 |
High payload and targeted release of anthracyclines by aptamer-tethered DNA nanotrains - Thermodynamic and release kinetic study.
Topics: Anthracyclines; Antineoplastic Agents; Aptamers, Nucleotide; Cell Line, Tumor; Cell Survival; Daunorubicin; DNA; Doxorubicin; Drug Carriers; Drug Delivery Systems; Epirubicin; HeLa Cells; Humans; Nanostructures | 2020 |
Profound Nanoscale Structural and Biomechanical Changes in DNA Helix upon Treatment with Anthracycline Drugs.
Topics: Anthracyclines; Antibiotics, Antineoplastic; Cell Nucleus; Computer Simulation; Daunorubicin; DNA, Single-Stranded; Doxorubicin; Epirubicin; Humans; Intercalating Agents; Microscopy, Atomic Force; Molecular Dynamics Simulation; Nucleic Acid Conformation; Optical Tweezers | 2020 |
Multicomponent Synthesis, Binding Mode, and Structure-Activity Relationship of Selective Histone Deacetylase 6 (HDAC6) Inhibitors with Bifurcated Capping Groups.
Topics: Animals; Antineoplastic Agents; Bortezomib; Cell Line, Tumor; Daunorubicin; Drug Screening Assays, Antitumor; Drug Synergism; Epirubicin; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Humans; Microsomes, Liver; Molecular Structure; Protein Binding; Structure-Activity Relationship; Tetrazoles | 2020 |
Cancer-Targeted Controlled Delivery of Chemotherapeutic Anthracycline Derivatives Using Apoferritin Nanocage Carriers.
Topics: Anthracyclines; Antibiotics, Antineoplastic; Apoferritins; Cell Line, Tumor; Daunorubicin; Delayed-Action Preparations; Doxorubicin; Drug Delivery Systems; Epirubicin; HeLa Cells; Humans; Hydrophobic and Hydrophilic Interactions; Nanostructures; Neoplasms | 2021 |
Development and application of a liquid chromatography coupled to mass spectrometry method for the simultaneous determination of 23 antineoplastic drugs at trace levels.
Topics: Antineoplastic Agents; Busulfan; Carboplatin; Chromatography, Liquid; Cyclophosphamide; Cytarabine; Dacarbazine; Daunorubicin; Docetaxel; Doxorubicin; Epirubicin; Etoposide; Fluorouracil; Ganciclovir; Humans; Idarubicin; Ifosfamide; Irinotecan; Methanol; Methotrexate; Oxaliplatin; Paclitaxel; Pemetrexed; Tandem Mass Spectrometry; Topotecan; Vinblastine; Vincristine; Water | 2022 |