Page last updated: 2024-08-23

daunorubicin and digoxin

daunorubicin has been researched along with digoxin in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19908 (32.00)18.7374
1990's1 (4.00)18.2507
2000's10 (40.00)29.6817
2010's5 (20.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Hargrove, P; Kim, RB; Lan, LB; Lecureur, V; Schuetz, EG; Schuetz, JD; Sun, D1
Komada, F; Nishiguchi, K; Okumura, K; Sakaeda, T; Takara, K; Tanigawara, Y1
Adachi, Y; Sugiyama, Y; Suzuki, H1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, X; Lin, X; Skolnik, S; Wang, J1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Burns, JH; Dow, JW2
Bódis, L; Herr, G; Nagy, L; Patakfalvi, A1
Kundv, D; Smith, BJ1
Burns, JH; Capps, NE; Dow, JW; Nigdikar, S; Walker, EJ1
Dienstl, F; Gmeiner, R; Knapp, E; Schwingshackl, A; Schwingshackl, H1
Jacobs, P; Opie, LH; Saman, S1
Bossa, R; Galatulas, I; Spiti, R1
Borst, P; Sarkadi, B; Smith, AJ; Szabo, K; Szakacs, G; van Helvoort, A; van Meer, G; Varadi, A; Welker, E1
Katoh, M; Nakajima, M; Yamazaki, H; Yokoi, T2
Kakumoto, M; Kita, T; Kobayashi, H; Nakamura, T; Okamura, N; Okumura, K; Sakaeda, T; Takara, K; Yagami, T1
Asashi, S; Higuchi, T; Katoh, M; Suzuyama, N; Takeuchi, T; Yokoi, T; Yoshitomi, S1
Kakumoto, M; Kobayashi, H; Ohnishi, N; Okumura, K; Sakaeda, T; Takara, K; Tanigawara, Y; Yokoyama, T1
Kim, HS; Kim, JH; Kim, SR; Ko, SG; Lee, JH; Shin, HJ; Shin, YC; Song, IS1
Cai, YD; Chen, L; Huang, T; Kong, X; Yang, J; Zheng, M1
Aalikhani, M; Alikhani, M; Bazi, Z; Oladnabi, M; Shamsabadi, F1

Reviews

1 review(s) available for daunorubicin and digoxin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

24 other study(ies) available for daunorubicin and digoxin

ArticleYear
Cloning and expression of murine sister of P-glycoprotein reveals a more discriminating transporter than MDR1/P-glycoprotein.
    Molecular pharmacology, 2000, Volume: 57, Issue:1

    Topics: Amino Acid Sequence; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Cells, Cultured; Cloning, Molecular; DNA, Complementary; Humans; Karyotyping; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Sequence Homology, Amino Acid

2000
Cellular pharmacokinetic aspects of reversal effect of itraconazole on P-glycoprotein-mediated resistance of anticancer drugs.
    Biological & pharmaceutical bulletin, 1999, Volume: 22, Issue:12

    Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Biological Transport; Cells, Cultured; Daunorubicin; Dihydropyridines; Doxorubicin; Drug Interactions; Drug Resistance, Neoplasm; Humans; Itraconazole; Photoaffinity Labels; Swine; Transfection; Tritium; Vinblastine

1999
Comparative studies on in vitro methods for evaluating in vivo function of MDR1 P-glycoprotein.
    Pharmaceutical research, 2001, Volume: 18, Issue:12

    Topics: Adenosine Triphosphate; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Caco-2 Cells; Cell Membrane Permeability; Dose-Response Relationship, Drug; Humans; Hydrolysis; LLC-PK1 Cells; Male; Mice; Mice, Knockout; Models, Biological; Pharmaceutical Preparations; Swine; Tissue Distribution; Transfection

2001
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity

2011
Uncoupling of work and adenosine triphosphate utilization in Daunorubicin cardiotoxicity.
    Biochemical Society transactions, 1978, Volume: 6, Issue:5

    Topics: Adenosine Triphosphate; Animals; Daunorubicin; Digoxin; In Vitro Techniques; Male; Mitochondria, Heart; Myocardial Contraction; Myocardium; Phosphocreatine; Rats

1978
[Possibility for the prevention of cardio toxic effect of Cerubidin].
    Orvosi hetilap, 1975, Aug-24, Volume: 116, Issue:34

    Topics: Daunorubicin; Digoxin; Heart; Heart Diseases; Humans; Leukemia, Myeloid, Acute

1975
Letter: Digoxin does not prevent daunorubicin or adriamycin from binding to rat heart muscle.
    British journal of cancer, 1976, Volume: 33, Issue:2

    Topics: Animals; Binding Sites; Daunorubicin; Digitoxin; Digoxin; Doxorubicin; Heart; Male; Myocardium; Propranolol; Rats; Razoxane

1976
Characterization of digoxin binding and daunorubicin uptake by isolated mature rat cardiac myocytes.
    Biochemical pharmacology, 1985, Jun-01, Volume: 34, Issue:11

    Topics: Amino Acids; Animals; Binding Sites; Calmodulin; Daunorubicin; Digoxin; In Vitro Techniques; Myocardium; Protein Biosynthesis; Rats; Rats, Inbred Strains

1985
[The effect of cytostatic therapy on hemodynamics (author's transl)].
    Medizinische Klinik, 1974, Feb-15, Volume: 69, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents; Blood Circulation Time; Blood Pressure; Cardiac Output; Cardiac Volume; Child; Child, Preschool; Cortisone; Cytarabine; Daunorubicin; Digoxin; Electrocardiography; Female; Heart Failure; Heart Function Tests; Hemodynamics; Hodgkin Disease; Humans; Leukemia, Lymphoid; Lymphoma, Non-Hodgkin; Male; Middle Aged; Sex Factors; Time Factors; Vincristine

1974
Mechanism of acute anthracycline cardiotoxicity in isolated rat hearts: carminomycin versus daunomycin.
    Cancer research, 1984, Volume: 44, Issue:4

    Topics: Animals; Atrial Function; Calcium; Carubicin; Coenzymes; Daunorubicin; Digoxin; Heart; Heart Atria; In Vitro Techniques; Isoproterenol; Male; Rats; Ubiquinone

1984
Effect of daunomycin on myocardial contractility and on the action of beta-methyldigoxin.
    Pharmacology, 1980, Volume: 21, Issue:6

    Topics: Animals; Daunorubicin; Digoxin; Dose-Response Relationship, Drug; Guinea Pigs; Medigoxin; Myocardial Contraction

1980
Daunorubicin-induced myocardial failure: reversal by digoxin of an inability to use ATP for contraction.
    Journal of molecular and cellular cardiology, 1980, Volume: 12, Issue:1

    Topics: Adenosine Triphosphate; Animals; Blood Pressure; Daunorubicin; Digoxin; Heart; Male; Myocardial Contraction; Perfusion; Rats

1980
MDR3 P-glycoprotein, a phosphatidylcholine translocase, transports several cytotoxic drugs and directly interacts with drugs as judged by interference with nucleotide trapping.
    The Journal of biological chemistry, 2000, Aug-04, Volume: 275, Issue:31

    Topics: Adenosine Triphosphate; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Biological Transport; Cell Polarity; Cells, Cultured; Cyclosporine; Cyclosporins; Cytotoxins; Daunorubicin; Digoxin; Epithelial Cells; Humans; Ivermectin; Kidney; Paclitaxel; Pharmaceutical Preparations; Phosphatidylcholines; Recombinant Proteins; Spodoptera; Swine; Verapamil; Vinblastine

2000
Inhibitory potencies of 1,4-dihydropyridine calcium antagonists to P-glycoprotein-mediated transport: comparison with the effects on CYP3A4.
    Pharmaceutical research, 2000, Volume: 17, Issue:10

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Calcium Channel Blockers; Cell Line; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Daunorubicin; Digoxin; Dihydropyridines; Humans; Mixed Function Oxygenases; Substrate Specificity; Transfection; Tritium

2000
Inhibitory effects of CYP3A4 substrates and their metabolites on P-glycoprotein-mediated transport.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2001, Volume: 12, Issue:4

    Topics: Amiodarone; Animals; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Daunorubicin; Digoxin; Enzyme Inhibitors; GABA Modulators; Gonadal Steroid Hormones; Humans; LLC-PK1 Cells; Midazolam; Mixed Function Oxygenases; Nifedipine; Phthalazines; Swine; Testosterone

2001
Effects of carvedilol on MDR1-mediated multidrug resistance: comparison with verapamil.
    Cancer science, 2003, Volume: 94, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Calcium Channel Blockers; Carbazoles; Carvedilol; Cell Division; Cell Line; Daunorubicin; Digoxin; DNA, Complementary; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Epithelial Cells; Fluorouracil; HeLa Cells; Humans; Inhibitory Concentration 50; Kidney; Paclitaxel; Propanolamines; Swine; Transfection; Verapamil; Vinblastine

2003
Species differences of inhibitory effects on P-glycoprotein-mediated drug transport.
    Journal of pharmaceutical sciences, 2007, Volume: 96, Issue:6

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cyclosporine; Daunorubicin; Digoxin; Dogs; Dose-Response Relationship, Drug; Humans; Mice; Quinidine; Rats; Species Specificity; Verapamil

2007
Effects of alpha-adrenoceptor antagonist doxazosin on MDR1-mediated multidrug resistance and transcellular transport.
    Oncology research, 2009, Volume: 17, Issue:11-12

    Topics: Adrenergic alpha-Antagonists; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Daunorubicin; Digoxin; Doxazosin; Drug Resistance, Multiple; HeLa Cells; Humans; Neoplasm Proteins; Prazosin; Vinblastine

2009
Different transport activity of human triallelic MDR1 893Ala/Ser/Thr variant and its association with herb extracts.
    Phytotherapy research : PTR, 2011, Volume: 25, Issue:8

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Daunorubicin; Dictamnus; Digoxin; Genes, MDR; Genetic Variation; Herb-Drug Interactions; Humans; LLC-PK1 Cells; Oocytes; Plant Extracts; Poria; Rhus; Swine; Xenopus laevis

2011
The Use of Chemical-Chemical Interaction and Chemical Structure to Identify New Candidate Chemicals Related to Lung Cancer.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Animals; Antineoplastic Agents; Arsenicals; Berberine; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Colchicine; Daunorubicin; Digoxin; Drug Discovery; Humans; Lung; Lung Neoplasms; Ouabain; Prednisone; Small Cell Lung Carcinoma; Tretinoin

2015
In silico drug repurposing for the treatment of heart diseases using gene expression data and molecular docking techniques.
    Biochemical and biophysical research communications, 2021, 10-01, Volume: 572

    Topics: Aminoisobutyric Acids; Aminopterin; Bridged Bicyclo Compounds, Heterocyclic; Cyclopropanes; Daunorubicin; Digoxin; Drug Repositioning; Gene Expression; Heart Diseases; Humans; Lactams, Macrocyclic; Leucine; Ligands; Methylergonovine; Molecular Docking Simulation; Morpholines; Proline; Quinoxalines; Sulfonamides

2021