Page last updated: 2024-08-23

daunorubicin and dexrazoxane

daunorubicin has been researched along with dexrazoxane in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's6 (75.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Austin, CA; Bavlovič Piskáčková, H; Jirkovská, A; Jirkovský, E; Karabanovich, G; Korábečný, J; Kubeš, J; Kučera, T; Melnikova, I; Nováková, L; Roh, J; Šimůnek, T; Skalická, V; Škoda, J; Štěrba, M1
Haskova, P; Jansova, H; Machacek, M; Mackova, E; Simunek, T; Sterba, M; Tichotova, L; Vavrova, A1
Adamcová, M; Chládek, J; Geršl, V; Hroch, M; Jansová, H; Jirkovská-Vávrová, A; Jirkovský, E; Lenčová-Popelová, O; Mazurová, Y; Pokorná, Z; Šimůnek, T; Štěrba, M; Vostatková-Tichotová, L1
Bures, J; Jansova, H; Jirkovska, A; Karabanovich, G; Kovarikova, P; Roh, J; Sestak, V; Simunek, T; Sterba, M1
Caballero Romero, Á; Cabeza Barrera, J; Delgado Ureña, MT; Librada Porriño-Bustamante, M; Megías Fernández, MT; Salmerón García, A1

Reviews

2 review(s) available for daunorubicin and dexrazoxane

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Extravasation accidents with liposomal/liposomal pegylated anthracyclines treated with dexrazoxane: an overview and outcomes.
    Anti-cancer drugs, 2018, Volume: 29, Issue:9

    Topics: Animals; Anthracyclines; Antibiotics, Antineoplastic; Daunorubicin; Dexrazoxane; Doxorubicin; Extravasation of Diagnostic and Therapeutic Materials; Humans; Liposomes; Polyethylene Glycols

2018

Other Studies

6 other study(ies) available for daunorubicin and dexrazoxane

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Structure-Activity Relationship Study of Dexrazoxane Analogues Reveals ICRF-193 as the Most Potent Bisdioxopiperazine against Anthracycline Toxicity to Cardiomyocytes Due to Its Strong Topoisomerase IIβ Interactions.
    Journal of medicinal chemistry, 2021, 04-08, Volume: 64, Issue:7

    Topics: Animals; Animals, Newborn; Cardiotonic Agents; Cardiotoxicity; Cell Line, Tumor; Cell Proliferation; Daunorubicin; Diketopiperazines; DNA Topoisomerases, Type II; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Myocytes, Cardiac; Piperazines; Protein Binding; Rats, Wistar; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Structure-Activity Relationship; Topoisomerase II Inhibitors

2021
Catalytic inhibitors of topoisomerase II differently modulate the toxicity of anthracyclines in cardiac and cancer cells.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Animals; Animals, Newborn; Anthracyclines; Biocatalysis; Caspases; Cell Cycle; Cell Proliferation; Cell Survival; Cells, Cultured; Daunorubicin; Dexrazoxane; DNA Topoisomerases, Type II; Doxorubicin; Drug Interactions; Flow Cytometry; Glutathione; Glutathione Disulfide; HL-60 Cells; Humans; Myocytes, Cardiac; Piperazines; Rats; Rats, Wistar; Thiobarbiturates; Topoisomerase II Inhibitors

2013
Cardioprotective effects of inorganic nitrate/nitrite in chronic anthracycline cardiotoxicity: Comparison with dexrazoxane.
    Journal of molecular and cellular cardiology, 2016, Volume: 91

    Topics: Animals; Antibiotics, Antineoplastic; Cardiotonic Agents; Cardiotoxicity; Daunorubicin; Dexrazoxane; DNA Topoisomerases, Type II; DNA-Binding Proteins; Drug Administration Schedule; Infusions, Intravenous; Male; Myocardium; Myocytes, Cardiac; Nitrates; Rabbits; Sodium Nitrite

2016
Investigation of novel dexrazoxane analogue JR-311 shows significant cardioprotective effects through topoisomerase IIbeta but not its iron chelating metabolite.
    Toxicology, 2017, 12-01, Volume: 392

    Topics: Animals; Animals, Newborn; Anthracyclines; Cardiotonic Agents; Cardiotoxicity; Cell Proliferation; Cells, Cultured; Daunorubicin; Dexrazoxane; Diketopiperazines; DNA Topoisomerases, Type II; Iron; Iron Chelating Agents; Myocytes, Cardiac; Rats; Rats, Wistar; Structure-Activity Relationship

2017