Page last updated: 2024-08-23

daunorubicin and cyclosporine

daunorubicin has been researched along with cyclosporine in 127 studies

Research

Studies (127)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	72 (56.69)	18.2507
2000's	43 (33.86)	29.6817
2010's	9 (7.09)	24.3611
2020's	3 (2.36)	2.80

Authors

Authors	Studies
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
Hargrove, P; Kim, RB; Lan, LB; Lecureur, V; Schuetz, EG; Schuetz, JD; Sun, D	1
Aubé, J; Borchardt, RT; Gao, J; Murase, O; Schowen, RL	1
Bates, S; Litman, T; Nagy, Z; Ozvegy, C; Sarkadi, B; Szakács, G; Váradi, A	1
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA	1
Adachi, Y; Sugiyama, Y; Suzuki, H	1
Borchardt, RT; Horie, K; Tang, F	2
Casciano, CN; Clement, RP; Johnson, WW; Wang, EJ	1
Globisch, C; Kassack, MU; Klinkhammer, W; Müller, H; Pajeva, IK; Wiese, M	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chen, X; Lin, X; Skolnik, S; Wang, J	1
Clardy, J; Derbyshire, ER; Mota, MM; Prudêncio, M	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bao, XZ; Cai, Y; Cui, ZN; Huang, Z; Li, YS; Liu, GJ; Wang, H; Wang, J; Wang, SJ; Wei, B; Wu, R; Yang, X; Ye, XY; Zhao, DS	1
Delmer, A; Helou, C; Marie, JP; Thevenin, D; Zittoun, R	1
Carpentier, Y; Desoize, B; Gorisse, MC	1
Osann, K; Slater, LM; Sweet, P	1
Friche, E; Jensen, PB; Nissen, NI	1
Cumber, PM; Hoy, T; Jacobs, A; Padua, RA; Tsuruo, T; Whittaker, JA	1
Bender-Götze, C; Dopfer, R; Ebell, W; Ehninger, G; Friedrich, W; Gadner, H; Henze, G; Klingebiel, T; Peters, C; Riehm, H	1
Arao, S; Fukumoto, M; Hiai, H; Hirai, M; Kakehi, Y; Kim, WJ; Yoshida, O	1
Cornblatt, B; Doyle, LA; Ross, DD; Tong, Y; Yang, W	1
Henry, TR; Solem, LE; Wallace, KB	1
Hirai, M; Hori, R; Kakehi, Y; Komano, T; Shimizu, T; Tanaka, K; Tanigawara, Y; Ueda, K; Yasuhara, M; Yoshida, O	1
Anzai, S; Fujimaki, K; Fujisawa, S; Fukawa, H; Hattori, M; Motomura, S; Okubo, T	1
Aszalos, A; Gottesman, MM; Pandey, R; Pine, PS	1
Berlion, M; Dieterlen, A; Lucas, C; Marchal, S; Merlin, JL; Poullain, MG; Ramacci, C; Schultz, G	1
Miller, DS	1
Ichimura, K; Kashiwagura, T; Kawahara, K; Koike, M; Matsui, W; Takeguchi, N	1
Christians, U; Demmer, A; Hoof, T; Tümmler, B	1
Bors, V; Dorent, R; Gandjbakhch, I; Ghoussoub, JJ; Nataf, P; Pavie, A; Tedy, G; Vaissier, E	1
Lucas, C; Marchal, S; Merlin, JL; Paraire, M; Poullain, MG; Ramacci, C	1
Bunge, A; Dietel, M; Hasmann, M; Herzig, I; Löser, R; Schaefer, B; Seidel, A; Steidtmann, K	1
Jiang, XR; Kelsey, SM; Newland, AC; Wu, YL	1
Chin-Yee, I; Crowther, MA; Daly, S; Keeney, M; Wright, L	1
Renfro, JL; Sussman-Turner, C	1
Coley, HM; Twentyman, PR; Workman, P	1
Boogaerts, MA; Van Acker, KL; Van Hove, LM	1
Jachez, B; Loor, F	1
Bhalla, K; Bullock, G; Huang, Y; Ibrado, AM; Mahoney, ME; Ponnathpur, V; Ray, S; Self, S; Tang, C; Tourkina, E	1
Björkholm, M; Gruber, A; Larsson, R; Nygren, P; Peterson, C	1
Boesch, D; Loor, F	1
Boesch, D; Emmer, G; Jachez, B; Loor, F	1
Braquet, P; Coulomb, H; Faussat-Suberville, AM; Marie, JP; Principe, P	1
al-Sabah, A; Baines, P; Burnett, A; Hoy, T; Limaye, M; Padua, RA; Whittaker, J	1
Böhme, M; Büchler, M; Jedlitschky, G; Keppler, D; Leier, I	1
Collins, PW; Jiang, XR; Macey, MG; Newland, AC	1
Faussat-Suberville, AM; Marie, JP; Zhou, D; Zittoun, R	1
Lee, EJ; Ordóñez, JV; Ross, DD; Schiffer, CA; Sridhara, R; Wooten, PJ	1
Baier, M; Dalton, W; Dorr, R; Futscher, B; Greer, J; Hutter, J; List, AF; Salmon, S; Spier, C; Wolff, S	1
Twentyman, PR; Wright, KA	1
Cornblatt, B; Lee, EJ; Levy, C; Ross, DD; Schiffer, CA; Sridhara, R; Tong, Y; Wooten, PJ	1
Barrand, MA; Center, MS; Rhodes, T; Twentyman, PR	1
Jelkmann, W; Wolff, M	1
Chihara, K; Kitazawa, F; Nagasawa, K; Natazuka, T; Nomiyama, M; Ohnishi, N; Takara, K; Tsumura, A; Yokoyama, T	1
Ayesh, S; Lan, LB; Lyubimov, E; Pashinsky, I; Stein, WD	1
Berlion, M; Kernaleguen, D; Le Bot, MA; Riché, C; Simon, I	1
Ríhová, B	1
Beglinger, C; Drewe, J; Fricker, G; Gutmann, H; Huwyler, J	1
Didier, A; Loor, F; Wenger, J	1
Alshammari, S; Anderson, L; Chin-Yee, I; Kadri, M; Keeney, M	1
Annable, T; Boni, JP; Citeralla, RV; Collins, KI; Greenberger, LM; Hallett, WA; Kramer, R; Lai, FM; May, MK; Powell, D	1
Gosland, M; Hoffman, T; Huang, L; Liu, Y; Vore, M	1
Algour, N; Ayesh, S; Lyubimov, E; Stein, WD	1
Abbadessa, V; Cajozzo, A; Gancitano, RA; Musso, M; Perricone, R; Porretto, F; Tolomeo, M	1
Chen, H; Choi, CH; Hedley, DW; Ling, V; Minden, MD; Xie, SX	1
Ford, PJ; Germann, UA; Harding, MW; Mason, VS; Shlyakhter, D	1
Hirai, M; Hori, R; Inui, K; Takano, M; Tanaka, K; Tanigawara, Y; Ueda, K	1
Choi, CH; Ling, V	1
Ashman, LK; Sincock, PM	1
Borg, AG; Burgess, R; Fisher, A; Grey, M; Wood, P; Yin, JA	1
Garnier-Suillerot, A; Mankhetkorn, S	1
Li, S; Wang, C; Yao, C	1
Fox, K; Lee, P; Ling, V; Shapiro, AB; Yang, YD	1
den Boer, ML; Henze, G; Janka-Schaub, GE; Kazemier, KM; Pieters, R; Veerman, AJ	1
Lang, J; Shen, K; Zhu, L	1
Aszalos, A; Weaver, JL	1
Bour, C; Colosetti, P; Guerci, AP; Guerci, O; Kataki, A; Marchal, S; Merlin, JL	1
Chi, XS; He, QY; Pang, DB; Xue, SB; Zhang, HQ	1
Barbui, T; Bassan, R; Chiodini, B	1
de Vries, EG; Eriks-Fluks, L; Franssen, EJ; Hendrikse, NH; Hospers, GA; Vaalburg, W; van der Graaf, WT; Willemsen, AT	1
Aszalos, A; Molnár, J; Ocsovszki, I; Szabó, D; Szabó, G	1
Elgie, AW; Lewandowicz, GM; Sargent, JM; Taylor, CG; Williamson, CJ	1
Langabeer, S; Pallis, M; Russell, NH; Turzanski, J	1
Calvo, F; Hantz, E; Kawakami, M; Larue, V; Le Moyec, L; Legrand, O; Marie, JP; Taillandier, E	1
Borst, P; Sarkadi, B; Smith, AJ; Szabo, K; Szakacs, G; van Helvoort, A; van Meer, G; Varadi, A; Welker, E	1
Atadja, P; Cohen, D; Roninson, IB; Uchiyama, N; Watanabe, T	1
Akasya, E; Büyükbabani, N; Diz-Küçükkaya, R; Oncü, S; Ozkaya-Bayazit, E; Pekçelen, Y	1
Landwojtowicz, E; Seelig, A	1
de Witte, T; Linssen, P; Masereeuw, R; Muus, P; Raymakers, R; Smeets, M; Vierwinden, G	1
Ashman, L; Cole, S; Ferrao, P; Sincock, P	1
Burnett, AK; Liu Yin, JA; Rees, JK; Wheatley, K	1
Azevedo, I; Keating, E; Martel, F	1
Lou, F; Pu, J; Zhou, Q	1
Appelbaum, FR; Doroshow, JH; Dorr, R; Head, DR; Hynes, HE; Karanes, C; Kopecky, KJ; List, AF; Persons, DL; Shurafa, M; Slovak, ML; Willman, CL	1
Appelbaum, FR	1
Albertioni, F; Eriksson, S; Lotfi, K; Månsson, E; Peterson, C	1
Eriksen, J; Friche, E; Maare, C; Nielsen, D; Skovsgaard, T	1
Ikeda, Y; Matsuzaki, M; Sakemi, T; Sano, M	1
Gruber, A; Knaust, E; Peterson, C; Porwit-MacDonald, A; Xu, D	1
Apostolidou, E; Cortes, J; Estey, E; Giles, FJ; Kantarjian, H; Tsimberidou, A	1
Litman, T; Skovsgaard, T; Stein, WD	1
Aubert, D; Bonhomme, A; Millot, JM; Pinon, JM; Sauvage, V	1
Corea, G; Di Pietro, A; Dumontet, C; Fattorusso, E; Lanzotti, V; Motti, R; Simon, PN	1
Takeshita, A	1
Cheng, HY; Li, SW; Xue, SB; Zhang, HQ	1
Garweg, JG; Goldblum, D; Wegmann-Burns, M	1
Fekete, MR; McBride, WH; Pajonk, F	1
Hua, DH; Lou, K; Perchellet, EM; Perchellet, JP; Wang, Y; Ward, MM	1
Bader, P; Boppana, S; Dormann, S; Fisch, P; Goebel, H; Jung, A; Kontny, U; Niemeyer, C; Peters, A; Strahm, B; Werner, M	1
Bacsó, Z; Fenyvesi, F; Goda, K; Juhász, I; Krasznai, Z; Márián, T; Megyeri, A; Nagy, H; Szabó, G; Vecsernyés, M	1
Asashi, S; Higuchi, T; Katoh, M; Suzuyama, N; Takeuchi, T; Yokoi, T; Yoshitomi, S	1
Gan, LS; Liu, N; Miwa, GT; Xia, CQ	1
Emel'yanov, MO; Korystov, YN; Korystova, AF; Kublik, LN; Shaposhnikova, VV	1
Hasegawa, H; Kitagawa, S; Nabekura, T; Tachikawa, E; Takahashi, T	1
Bayet, C; Darbour, N; Di Pietro, A; Dijoux-Franca, MG; Doreau, A; Dumontet, C; Guilet, D; Nguyen, VT; Phung, BH; Raad, I	1
Coburger, C; Hilgeroth, A; Lage, H; Molnár, J	1
Chen, SG; Li, GY; Liu, JZ; Wang, CB; Wang, LX; Zhang, B	1
Appelbaum, FR; Chauncey, TR; Chen, IM; Dakhil, SR; Erba, HP; Gundacker, H; Kopecky, KJ; List, AF; Shadman, M; Slovak, ML; Willman, CL	1
Arnoult, C; Barattin, R; Bourges, K; Boutonnat, J; D'Hardemare, AD; Gerby, B; Hardy, G; Olivares, J; Ronot, X	1
Fodor, Z; Galuska, L; Goda, K; Hernádi, Z; Krasznai, ZT; Mikecz, P; Szabó, G; Tóth, A	1
Imasaka, T; Kaneta, T; Mbuna, J	1
Berkowitz, J; Bernard, L; Hogge, DE; Kim, HP; Nitta, J	1
Wang, H; Wang, X; Yang, D; Zhang, R	1

Reviews

3 review(s) available for daunorubicin and cyclosporine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Antibody-targeted polymer-bound drugs. Folia microbiologica, 1995, Volume: 40, Issue:4 Topics: Acrylamides; Animals; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antineoplastic Agents; Chlorophyllides; Clinical Trials as Topic; Cyclosporine; Daunorubicin; Doxorubicin; Histocompatibility Antigens Class II; Humans; Immune System Diseases; Immunoconjugates; Immunosuppressive Agents; Lysosomes; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Polymethacrylic Acids; Porphyrins; Radiation-Sensitizing Agents; T-Lymphocyte Subsets; Thy-1 Antigens; Tissue Distribution	1995
[Recent advances in the treatment of acute myelogenous leukemia: a view of the new agents]. [Rinsho ketsueki] The Japanese journal of clinical hematology, 2003, Volume: 44, Issue:12 Topics: Alkyl and Aryl Transferases; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Benzoates; Cyclosporine; Cytarabine; Daunorubicin; Drug Design; Farnesyltranstransferase; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Neoplasm Recurrence, Local; Nucleosides; Oxides; Prognosis; Radioisotopes; Remission Induction; Tetrahydronaphthalenes; Topoisomerase Inhibitors; Tretinoin; Verapamil	2003

Trials

8 trial(s) available for daunorubicin and cyclosporine

Article	Year
Allogeneic bone marrow transplantation for childhood acute lymphoblastic leukemia in second remission after intensive primary and relapse therapy according to the BFM- and CoALL-protocols: results of the German Cooperative Study. Blood, 1991, Nov-15, Volume: 78, Issue:10 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Child; Child, Preschool; Cyclophosphamide; Cyclosporine; Daunorubicin; Etoposide; Follow-Up Studies; Graft vs Host Disease; Humans; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Recurrence; Time Factors; Transplantation, Homologous; Vincristine; Whole-Body Irradiation	1991
Phase I/II trial of cyclosporine as a chemotherapy-resistance modifier in acute leukemia. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1993, Volume: 11, Issue:9 Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Child; Child, Preschool; Cyclosporine; Daunorubicin; Drug Resistance; Female; Gene Expression; Humans; Leukemia, Myeloid; Male; Membrane Glycoproteins; Middle Aged; Neoplasm Proteins; Phenotype; Survival Analysis; Treatment Outcome	1993
Relevance of p-glycoprotein for the enteral absorption of cyclosporin A: in vitro-in vivo correlation. British journal of pharmacology, 1996, Volume: 118, Issue:7 Topics: Adult; Alkaline Phosphatase; Antibiotics, Antineoplastic; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Caco-2 Cells; Cyclosporine; Daunorubicin; Humans; Immunohistochemistry; Immunosuppressive Agents; Intestinal Absorption; Intubation, Gastrointestinal; Male; Middle Aged	1996
Comparison of 'sequential' versus 'standard' chemotherapy as re-induction treatment, with or without cyclosporine, in refractory/relapsed acute myeloid leukaemia (AML): results of the UK Medical Research Council AML-R trial. British journal of haematology, 2001, Volume: 113, Issue:3 Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclosporine; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Administration Schedule; Etoposide; Female; Humans; Immunosuppressive Agents; Leukemia, Myeloid; Male; Middle Aged; Remission Induction	2001
Benefit of cyclosporine modulation of drug resistance in patients with poor-risk acute myeloid leukemia: a Southwest Oncology Group study. Blood, 2001, Dec-01, Volume: 98, Issue:12 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Cytarabine; Cytogenetic Analysis; Daunorubicin; Disease-Free Survival; Drug Interactions; Drug Resistance, Neoplasm; Gene Expression; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Risk Factors	2001
Pilot study of gemtuzumab ozogamicin, liposomal daunorubicin, cytarabine and cyclosporine regimen in patients with refractory acute myelogenous leukemia. Leukemia research, 2003, Volume: 27, Issue:10 Topics: Adolescent; Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cyclosporine; Cytarabine; Daunorubicin; Female; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Liposomes; Male; Middle Aged; Pilot Projects; Remission Induction; Salvage Therapy; Treatment Outcome	2003
Cyclosporine diminishes multidrug resistance in K562/ADM cells and improves complete remission in patients with acute myeloid leukemia. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2009, Volume: 63, Issue:8 Topics: Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Survival; Cyclosporine; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Fluorescent Dyes; Humans; Idarubicin; Inhibitory Concentration 50; K562 Cells; Leukemia, Myeloid, Acute; Male; Rhodamine 123; Time Factors; Treatment Outcome; Verapamil	2009
Sequential phase II Southwest Oncology Group studies (S0112 and S0301) of daunorubicin and cytarabine by continuous infusion, without and with ciclosporin, in older patients with previously untreated acute myeloid leukaemia. British journal of haematology, 2010, Volume: 148, Issue:1 Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Cytarabine; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Epidemiologic Methods; Female; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Proteins; Treatment Outcome	2010

Other Studies

116 other study(ies) available for daunorubicin and cyclosporine

Article	Year
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023
Cloning and expression of murine sister of P-glycoprotein reveals a more discriminating transporter than MDR1/P-glycoprotein. Molecular pharmacology, 2000, Volume: 57, Issue:1 Topics: Amino Acid Sequence; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Cells, Cultured; Cloning, Molecular; DNA, Complementary; Humans; Karyotyping; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Sequence Homology, Amino Acid	2000
A functional assay for quantitation of the apparent affinities of ligands of P-glycoprotein in Caco-2 cells. Pharmaceutical research, 2001, Volume: 18, Issue:2 Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Biological Transport, Active; Caco-2 Cells; Drug Interactions; Humans; Ligands; Models, Theoretical; Paclitaxel; Tritium	2001
Functional characterization of the human multidrug transporter, ABCG2, expressed in insect cells. Biochemical and biophysical research communications, 2001, Jul-06, Volume: 285, Issue:1 Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Cell Membrane; Cloning, Molecular; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Neoplasm Proteins; Recombinant Proteins; Spodoptera; Tumor Cells, Cultured	2001
Rational use of in vitro P-glycoprotein assays in drug discovery. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2 Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera	2001
Comparative studies on in vitro methods for evaluating in vivo function of MDR1 P-glycoprotein. Pharmaceutical research, 2001, Volume: 18, Issue:12 Topics: Adenosine Triphosphate; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Caco-2 Cells; Cell Membrane Permeability; Dose-Response Relationship, Drug; Humans; Hydrolysis; LLC-PK1 Cells; Male; Mice; Mice, Knockout; Models, Biological; Pharmaceutical Preparations; Swine; Tissue Distribution; Transfection	2001
Are MDCK cells transfected with the human MDR1 gene a good model of the human intestinal mucosa? Pharmaceutical research, 2002, Volume: 19, Issue:6 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Cell Line; Digoxin; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Genes, MDR; Humans; Intestinal Mucosa; Transfection	2002
Are MDCK cells transfected with the human MRP2 gene a good model of the human intestinal mucosa? Pharmaceutical research, 2002, Volume: 19, Issue:6 Topics: Animals; Caco-2 Cells; Cell Line; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Intestinal Mucosa; Mitochondrial Proteins; Multidrug Resistance-Associated Protein 2; Ribosomal Proteins; Saccharomyces cerevisiae Proteins; Transfection; Vinblastine	2002
Fluorescent substrates of sister-P-glycoprotein (BSEP) evaluated as markers of active transport and inhibition: evidence for contingent unequal binding sites. Pharmaceutical research, 2003, Volume: 20, Issue:4 Topics: ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Binding Sites; Biological Transport, Active; Biomarkers; Cells, Cultured; Drug Interactions; Fluorescent Dyes; Humans	2003
New functional assay of P-glycoprotein activity using Hoechst 33342. Bioorganic & medicinal chemistry, 2007, Dec-01, Volume: 15, Issue:23 Topics: Adenosine Triphosphatases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Fluoresceins; Humans; Microscopy, Fluorescence; Molecular Structure; Principal Component Analysis; Time Factors	2007
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2 Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity	2011
Liver-stage malaria parasites vulnerable to diverse chemical scaffolds. Proceedings of the National Academy of Sciences of the United States of America, 2012, May-29, Volume: 109, Issue:22 Topics: Animals; Anopheles; Antimalarials; Drug Evaluation, Preclinical; Hep G2 Cells; Humans; Inhibitory Concentration 50; Insect Vectors; Life Cycle Stages; Liver; Malaria; Malaria, Falciparum; Male; Mice; Mice, Inbred C57BL; Plasmodium berghei; Plasmodium falciparum; Treatment Outcome	2012
Design, synthesis and bioactivity study on 5-phenylfuran derivatives as potent reversal agents against P-glycoprotein-mediated multidrug resistance in MCF-7/ADR cell. European journal of medicinal chemistry, 2021, Apr-15, Volume: 216 Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Cell Line, Tumor; Cell Proliferation; Doxorubicin; Drug Design; Drug Resistance, Neoplasm; Furans; Humans; Molecular Docking Simulation; Paclitaxel; Structure-Activity Relationship; Tetrahydroisoquinolines	2021
In vitro effect of P-glycoprotein (P-gp) modulators on drug sensitivity of leukemic progenitors (CFU-L) in acute myelogenous leukemia (AML). Experimental hematology, 1992, Volume: 20, Issue:5 Topics: Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cefoperazone; Cyclosporine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Membrane Glycoproteins; Middle Aged; Mitoxantrone; Stem Cells; Tumor Cells, Cultured; Verapamil	1992
Evaluation of a method for detection of cells with reduced drug retention in solid tumours. Cytometry, 1992, Volume: 13, Issue:6 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Breast Neoplasms; Cell Survival; Chromatography, High Pressure Liquid; Culture Media; Cyclosporine; Daunorubicin; Drug Resistance; Female; Flow Cytometry; Friend murine leukemia virus; Humans; Hydrogen-Ion Concentration; Leukemia, Erythroblastic, Acute; Membrane Glycoproteins; Mice; Neoplasm Proteins; Neoplasms; Nephelometry and Turbidimetry; Reference Standards; Reproducibility of Results; Treatment Outcome; Tumor Cells, Cultured; Verapamil	1992
Synergistic interaction of cyclosporin A and verapamil on vincristine and daunorubicin resistance in multidrug-resistant human leukemia cells in vitro. Cancer chemotherapy and pharmacology, 1992, Volume: 30, Issue:2 Topics: Cyclosporine; Daunorubicin; Drug Resistance; Drug Synergism; Humans; Kinetics; Leukemia-Lymphoma, Adult T-Cell; Tumor Cells, Cultured; Verapamil; Vincristine	1992
Comparison of cyclosporin A and SDZ PSC833 as multidrug-resistance modulators in a daunorubicin-resistant Ehrlich ascites tumor. Cancer chemotherapy and pharmacology, 1992, Volume: 30, Issue:3 Topics: Animals; Carcinoma, Ehrlich Tumor; Cyclosporine; Cyclosporins; Daunorubicin; Drug Interactions; Drug Resistance; Tumor Cells, Cultured; Vincristine	1992
Increased drug accumulation ex vivo with cyclosporin in chronic lymphatic leukemia and its relationship to epitope masking of P-glycoprotein. Leukemia, 1991, Volume: 5, Issue:12 Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Chlorambucil; Cyclosporine; Daunorubicin; Drug Resistance; Humans; In Vitro Techniques; Membrane Glycoproteins; Neuraminidase; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured	1991
Multidrug resistance-associated protein-mediated multidrug resistance modulated by cyclosporin A in a human bladder cancer cell line. Japanese journal of cancer research : Gann, 1995, Volume: 86, Issue:10 Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Biological Transport; Cell Nucleus; Cyclosporine; Daunorubicin; DNA Primers; DNA Topoisomerases, Type I; Drug Resistance, Multiple; Gene Expression; Humans; Molecular Sequence Data; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured; Urinary Bladder Neoplasms	1995
Susceptibility of idarubicin, daunorubicin, and their C-13 alcohol metabolites to transport-mediated multidrug resistance. Biochemical pharmacology, 1995, Nov-09, Volume: 50, Issue:10 Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Breast Neoplasms; Cell Survival; Culture Media; Cyclosporine; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Stability; HL-60 Cells; Humans; Idarubicin; Intracellular Fluid; Tumor Cells, Cultured	1995
Disruption of mitochondrial calcium homeostasis following chronic doxorubicin administration. Toxicology and applied pharmacology, 1994, Volume: 129, Issue:2 Topics: Analysis of Variance; Animals; Body Weight; Calcium; Cyclosporine; Daunorubicin; Doxorubicin; Homeostasis; Male; Membrane Potentials; Mitochondria, Heart; Mitochondrial Swelling; Organ Size; Oxygen Consumption; Rats; Rats, Inbred F344; Ruthenium Red; Time Factors	1994
Cepharanthin, a multidrug resistant modifier, is a substrate for P-glycoprotein. The Journal of pharmacology and experimental therapeutics, 1995, Volume: 275, Issue:1 Topics: Alkaloids; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzylisoquinolines; Biological Transport, Active; Cells, Cultured; Cyclosporine; Daunorubicin; Drug Resistance, Multiple; Drug Synergism; Kinetics; Vinblastine	1995
[Intermittent-dose ara-C/daunomycin therapy combined with cyclosporin-A and G-CSF led to a fourth remission in a patient with acute promyelocytic leukemia]. [Rinsho ketsueki] The Japanese journal of clinical hematology, 1995, Volume: 36, Issue:8 Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclosporine; Cytarabine; Daunorubicin; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Promyelocytic, Acute; Middle Aged; Recurrence; Remission Induction	1995
Behavior of N-acylated daunorubicins in MDR1 gene transfected and parental cells. Biochemical pharmacology, 1995, Sep-07, Volume: 50, Issue:6 Topics: 3T3 Cells; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Division; Cyclosporine; Daunorubicin; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance, Multiple; Humans; Mice; Transfection; Tumor Cells, Cultured	1995
Influence of S9788, a new modulator of multidrug resistance, on the cellular accumulation and subcellular distribution of daunorubicin in P-glycoprotein-expressing MCF7 human breast adenocarcinoma cells. Cytometry, 1995, Aug-01, Volume: 20, Issue:4 Topics: Adenocarcinoma; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Cell Nucleus; Cyclosporine; Daunorubicin; Drug Resistance, Multiple; Female; Flow Cytometry; Humans; Neoplasm Proteins; Piperidines; Subcellular Fractions; Triazines; Tumor Cells, Cultured; Verapamil	1995
Daunomycin secretion by killfish renal proximal tubules. The American journal of physiology, 1995, Volume: 269, Issue:2 Pt 2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Buffers; Cyclosporine; Daunorubicin; Hydrogen-Ion Concentration; Image Processing, Computer-Assisted; Kidney Tubules, Proximal; Killifishes; Microscopy, Fluorescence; Television; Tetraethylammonium; Tetraethylammonium Compounds; Verapamil	1995
Inhibition of the multidrug efflux pump in isolated hepatocyte couplets by immunosuppressants FK506 and cyclosporine. Transplantation, 1993, Volume: 55, Issue:3 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bile Canaliculi; Cyclosporine; Daunorubicin; Drug Resistance; Fluoresceins; Fluorescent Dyes; Fura-2; Liver; Membrane Glycoproteins; Microscopy, Fluorescence; Progesterone; Rats; Signal Processing, Computer-Assisted; Tacrolimus; Verapamil; Vinblastine	1993
Reversal of multidrug resistance in Chinese hamster ovary cells by the immunosuppressive agent rapamycin. European journal of pharmacology, 1993, Jun-15, Volume: 246, Issue:1 Topics: Affinity Labels; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Cell Division; Cell Membrane; CHO Cells; Cricetinae; Cricetulus; Cyclosporine; Daunorubicin; Drug Resistance; Immunosuppressive Agents; Membrane Glycoproteins; Polyenes; Sirolimus; Succinimides; Tacrolimus; Vinca Alkaloids	1993
Heart transplantation is a valid therapeutic option for anthracycline cardiomyopathy. Transplantation proceedings, 1995, Volume: 27, Issue:2 Topics: Actuarial Analysis; Adult; Azathioprine; Cardiomyopathies; Cyclosporine; Daunorubicin; Doxorubicin; Female; Heart Transplantation; Humans; Immunosuppression Therapy; Male; Neoplasms; Prednisolone; Survival Rate	1995
[Effect of the modality of exposure on the action of S9788 on the modulation of multidrug resistance of human tumor cell lines]. Bulletin du cancer, 1994, Volume: 81, Issue:10 Topics: Adenocarcinoma; Antineoplastic Agents; Breast Neoplasms; Cyclosporine; Daunorubicin; Drug Resistance, Multiple; Humans; Leukemia; Piperidines; Triazines; Tumor Cells, Cultured; Verapamil	1994
Intracellular localization, vesicular accumulation and kinetics of daunorubicin in sensitive and multidrug-resistant gastric carcinoma EPG85-257 cells. Virchows Archiv : an international journal of pathology, 1995, Volume: 426, Issue:3 Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Cytochalasin B; Daunorubicin; Drug Resistance, Multiple; Flow Cytometry; Humans; Nocodazole; Polymerase Chain Reaction; RNA, Messenger; Stomach Neoplasms; Tumor Cells, Cultured	1995
Circumvention of P-glycoprotein-mediated drug resistance in human leukaemic cells by non-immunosuppressive cyclosporin D analogue, SDZ PSC 833. British journal of haematology, 1995, Volume: 90, Issue:2 Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Survival; Cyclosporine; Cyclosporins; Daunorubicin; Drug Resistance, Multiple; Fluorescent Antibody Technique; Humans; Leukemia, Erythroblastic, Acute; Leukemia, T-Cell; Tumor Cells, Cultured	1995
Validation of a single point flow cytometric assay for determining P-glycoprotein activity in multidrug resistant cell lines. Clinical and laboratory haematology, 1994, Volume: 16, Issue:3 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; CHO Cells; Cricetinae; Cricetulus; Cyclosporine; Daunorubicin; Drug Resistance, Multiple; Flow Cytometry; Fluorometry; Humans; Neoplasm Proteins; Tumor Cells, Cultured; Verapamil	1994
Heat-shock-stimulated transepithelial daunomycin secretion by flounder renal proximal tubule primary cultures. The American journal of physiology, 1995, Volume: 268, Issue:1 Pt 2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cells, Cultured; Cycloheximide; Cyclosporine; Daunorubicin; Epithelial Cells; Epithelium; Flounder; Hot Temperature; Immunohistochemistry; Kidney Tubules, Proximal; Kinetics; Microvilli; p-Aminohippuric Acid; Tetraethylammonium; Tetraethylammonium Compounds; Verapamil; Vinblastine	1995
[Pharmacological properties of S9788, a new modulator of multidrug resistance]. Bulletin du cancer, 1994, Volume: 81, Issue:2 Topics: Adjuvants, Immunologic; Antineoplastic Agents; Cyclosporine; Daunorubicin; Doxorubicin; Drug Resistance, Multiple; Humans; Piperidines; Spectrometry, Fluorescence; Triazines; Tumor Cells, Cultured; Vinblastine; Vincristine	1994
The efflux of anthracyclines in multidrug-resistant cell lines. Biochemical pharmacology, 1993, Oct-19, Volume: 46, Issue:8 Topics: Aclarubicin; Animals; Anthracyclines; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Cyclosporine; Daunorubicin; Doxorubicin; Drug Resistance; Humans; Membrane Glycoproteins; Mice; Phenotype; Tumor Cells, Cultured; Verapamil	1993
Evaluation of flow cytometry for multidrug resistance detection in low resistance K562 cells using daunorubicin and monoclonal antibodies. Cytometry, 1993, Volume: 14, Issue:7 Topics: Antibodies, Monoclonal; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Cyclosporine; Daunorubicin; Drug Resistance; Flow Cytometry; Gene Expression; Humans; Leukemia, Erythroblastic, Acute; Membrane Glycoproteins; Methotrexate; Neoplasm Proteins; Tumor Cells, Cultured; Verapamil; Vinblastine	1993
Atypical multi-drug resistance (MDR): low sensitivity of a P-glycoprotein-expressing human T lymphoblastoid MDR cell line to classical P-glycoprotein-directed resistance-modulating agents. Anti-cancer drugs, 1993, Volume: 4, Issue:6 Topics: Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Cell Division; Cyclosporine; Cyclosporins; Daunorubicin; Drug Resistance; Flow Cytometry; Humans; Leukemia-Lymphoma, Adult T-Cell; Membrane Glycoproteins; Peptides, Cyclic; Tumor Cells, Cultured; Verapamil	1993
Characterization of a human myeloid leukemia cell line highly resistant to taxol. Leukemia, 1994, Volume: 8, Issue:3 Topics: Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Cell Division; Cyclosporine; Daunorubicin; DNA, Neoplasm; Drug Resistance; Humans; Leukemia, Myeloid; Membrane Glycoproteins; Microtubules; Paclitaxel; Tumor Cells, Cultured; Verapamil	1994
A non-P-glycoprotein-mediated mechanism of vincristine transport which is affected by resistance modifiers and present in chemosensitive cells. Leukemia, 1994, Volume: 8, Issue:6 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Carrier Proteins; Cell Survival; Cells, Cultured; Cyclosporine; Daunorubicin; Drug Interactions; Drug Resistance; Drug Screening Assays, Antitumor; Gene Expression; Heart; Humans; Leukemia, Experimental; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Membrane Glycoproteins; Myocardium; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured; Verapamil; Vincristine	1994
Extent and persistence of P-glycoprotein inhibition in multidrug-resistant P388 cells after exposure to resistance-modifying agents. Anti-cancer drugs, 1994, Volume: 5, Issue:2 Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Cyclosporine; Cyclosporins; Daunorubicin; Drug Resistance; Extracellular Space; Leukemia P388; Membrane Glycoproteins; Mice; Molecular Sequence Data; Peptides, Cyclic; Verapamil	1994
SDZ 280-125: a cyclopeptolide endowed with an in vitro cyclosporin A-like profile of activity for the reversion of the P-glycoprotein-mediated multidrug resistance of tumor cells. Anti-cancer drugs, 1994, Volume: 5, Issue:3 Topics: Amino Acid Sequence; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; CHO Cells; Cricetinae; Cyclosporine; Daunorubicin; Drug Interactions; Drug Resistance; Drug Screening Assays, Antitumor; Humans; KB Cells; Leukemia P388; Mice; Molecular Sequence Data; Neoplasms, Experimental; Peptides, Cyclic; Tumor Cells, Cultured	1994
Flow cytometric monitoring of anthracycline accumulation after anti-neoplastic ether phospholipid treatment. Anti-cancer drugs, 1994, Volume: 5, Issue:3 Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Daunorubicin; Drug Interactions; Drug Screening Assays, Antitumor; Flow Cytometry; Humans; Leukemia, Myeloid; Leukemia, T-Cell; Phospholipid Ethers; Tumor Cells, Cultured; Verapamil	1994
In vitro drug resistance in acute myeloid and chronic B-lymphocytic leukaemic blasts and in normal blood and marrow populations. Leukemia research, 1994, Volume: 18, Issue:9 Topics: Acute Disease; Adult; Aged; Aged, 80 and over; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blast Crisis; Bone Marrow; Bone Marrow Cells; Cell Survival; Cells, Cultured; Cyclosporine; Daunorubicin; Drug Resistance; Drug Resistance, Multiple; Female; Fluorescent Antibody Technique; Humans; Idarubicin; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid; Male; Middle Aged; Monocytes; Reference Values	1994
ATP-dependent export pumps and their inhibition by cyclosporins. Advances in enzyme regulation, 1994, Volume: 34 Topics: Adenosine Triphosphate; Animals; Bile; Bile Canaliculi; Biological Transport, Active; Carrier Proteins; Cell Membrane; Cyclosporine; Cyclosporins; Daunorubicin; Drug Resistance, Multiple; Immunosuppression Therapy; Leukotriene C4; Male; Rats; Rats, Wistar; Taurocholic Acid	1994
Characterization and modulation of drug transport kinetics in K562 c1.6 daunorubicin-resistant cell line. British journal of haematology, 1994, Volume: 86, Issue:3 Topics: Antineoplastic Agents; Azides; Cell Survival; Cyclosporine; Daunorubicin; Drug Interactions; Drug Resistance; Glucose; Humans; Leukemia; Sodium Azide; Tumor Cells, Cultured	1994
Daunorubicin uptake by leukemic cells: correlations with treatment outcome and mdr1 expression. Leukemia, 1993, Volume: 7, Issue:6 Topics: Acute Disease; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Carrier Proteins; Cyclosporine; Daunorubicin; Drug Resistance; Gene Expression; Humans; In Vitro Techniques; Leukemia, Myeloid; Membrane Glycoproteins; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured	1993
Enhancement of daunorubicin accumulation, retention, and cytotoxicity by verapamil or cyclosporin A in blast cells from patients with previously untreated acute myeloid leukemia. Blood, 1993, Aug-15, Volume: 82, Issue:4 Topics: Adult; Aged; Aged, 80 and over; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Carrier Proteins; Cell Survival; Cyclosporine; Daunorubicin; Drug Resistance; Female; Humans; Leukemia, Myeloid, Acute; Male; Membrane Glycoproteins; Middle Aged; Tumor Cells, Cultured; Verapamil	1993
Derivation and characterisation of a mouse tumour cell line with acquired resistance to cyclosporin A. European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:3 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinosarcoma; Carrier Proteins; Cyclosporine; Daunorubicin; DNA, Neoplasm; Doxorubicin; Drug Resistance; Mammary Neoplasms, Experimental; Membrane Glycoproteins; Mice; Tumor Cells, Cultured; Verapamil; Vincristine	1993
Synergistic reversal of multidrug-resistance phenotype in acute myeloid leukemia cells by cyclosporin A and cremophor EL. Blood, 1994, Mar-01, Volume: 83, Issue:5 Topics: Cell Survival; Cyclosporine; Daunorubicin; Drug Resistance; Drug Synergism; Female; Glycerol; Humans; Leukemia, Myeloid, Acute; Male; Tumor Cells, Cultured	1994
Chemosensitisation and drug accumulation effects of cyclosporin A, PSC-833 and verapamil in human MDR large cell lung cancer cells expressing a 190k membrane protein distinct from P-glycoprotein. European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:3 Topics: Carcinoma, Non-Small-Cell Lung; Cyclosporine; Cyclosporins; Daunorubicin; Humans; Lung Neoplasms; Membrane Proteins; Molecular Weight; Neoplasm Proteins; Tumor Cells, Cultured; Verapamil; Vincristine	1993
Effects of chemotherapeutic and immunosuppressive drugs on the production of erythropoietin in human hepatoma cultures. Annals of hematology, 1993, Volume: 66, Issue:1 Topics: Animals; Antineoplastic Agents; Azathioprine; Colchicine; Cyclophosphamide; Cyclosporine; Cytarabine; Daunorubicin; Erythropoietin; Humans; Ifosfamide; Immunosuppressive Agents; L-Lactate Dehydrogenase; Liver Neoplasms, Experimental; Methotrexate; Organoplatinum Compounds; Tetrazolium Salts; Tumor Cells, Cultured; Vincristine	1993
Transport mechanism of anthracycline derivatives in human leukemia cell lines: uptake and efflux of pirarubicin in HL60 and pirarubicin-resistant HL60 cells. Cancer chemotherapy and pharmacology, 1996, Volume: 37, Issue:4 Topics: Analysis of Variance; Antibiotics, Antineoplastic; Antineoplastic Agents; Biological Transport, Active; Blotting, Northern; Cyclosporine; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Gene Expression Regulation, Neoplastic; Genistein; HL-60 Cells; Humans; Isoflavones; Leukemia; RNA, Messenger; RNA, Neoplasm; Temperature; Time Factors; Tumor Cells, Cultured; Verapamil	1996
Kinetic parameters for reversal of the multidrug pump as measured for drug accumulation and cell killing. Cancer chemotherapy and pharmacology, 1996, Volume: 38, Issue:2 Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Cell Survival; Cyclosporine; Cytotoxins; Daunorubicin; Drug Resistance, Multiple; Humans; Propafenone; Trifluoperazine; Vinblastine	1996
[Effect of S9788, cyclosporin A and verapamil on intracellular accumulation of doxorubicin, daunorubicin and daunorubicinol in primary rat hepatocyte culture]. Annales de biologie clinique, 1996, Volume: 54, Issue:1 Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Cyclosporine; Daunorubicin; Doxorubicin; Drug Resistance, Multiple; Liver; Piperidines; Rats; Rats, Sprague-Dawley; Triazines; Verapamil	1996
Decreased uptake of cyclosporin A by P-glycoprotein (Pgp) expressing CEM leukemic cells and restoration of normal retention by Pgp blockers. Anti-cancer drugs, 1995, Volume: 6, Issue:5 Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Cyclosporins; Daunorubicin; Doxorubicin; Drug Resistance, Multiple; Flow Cytometry; Humans; Immunosuppressive Agents; Leukemia, Monocytic, Acute; Leukemia, T-Cell; Mice; Peptides, Cyclic; Rhodamines; Tumor Cells, Cultured; Verapamil; Vinblastine	1995
Comparison of two methods to detect P-glycoprotein in patients with chronic lymphocytic leukaemia. Clinical and laboratory haematology, 1996, Volume: 18, Issue:2 Topics: Adult; Aged; Antibodies, Monoclonal; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Membrane; Cyclosporine; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Epitopes; Flow Cytometry; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Middle Aged; Reproducibility of Results; Sensitivity and Specificity	1996
alpha-(3,4-dimethyoxyphenyl)-3,4-dihydro-6,7-dimethoxy-alpha- [(4-methylphenyl)thio]-2(1H)-isoquinolineheptanenitrile (CL 329,753): a novel chemosensitizing agent for P-glycoprotein-mediated resistance with improved biological properties compared with ver Oncology research, 1996, Volume: 8, Issue:5 Topics: Affinity Labels; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Survival; Cyclosporine; Daunorubicin; Drug Resistance, Multiple; Humans; Isoquinolines; Transfection; Tumor Cells, Cultured; Verapamil	1996
MDR1 substrates/modulators protect against beta-estradiol-17beta-D-glucuronide cholestasis in rat liver. Cancer research, 1996, Nov-01, Volume: 56, Issue:21 Topics: Animals; Anion Transport Proteins; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bile; Carrier Proteins; Cholestasis; Chromatography, High Pressure Liquid; Cyclosporine; Daunorubicin; Estradiol; Male; Paclitaxel; Rats; Rats, Sprague-Dawley	1996
Reversal of P-glycoprotein is greatly reduced by the presence of plasma but can be monitored by an ex vivo clinical assay. Anti-cancer drugs, 1996, Volume: 7, Issue:6 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Daunorubicin; Drug Screening Assays, Antitumor; Humans; Kidney; Leukemia P388; Mice; Plasma; Quinidine; Verapamil; Vinblastine	1996
Comparative activity of idarubicin and idarubicinol in combination with cyclosporin A in multidrug-resistant leukemia cells. Cancer chemotherapy and pharmacology, 1996, Volume: 39, Issue:1-2 Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cyclosporine; Daunorubicin; Drug Resistance, Multiple; Flow Cytometry; Idarubicin; Immunosuppressive Agents; Tumor Cells, Cultured	1996
A novel energy dependent mechanism reducing daunorubicin accumulation in acute myeloid leukemia. Leukemia, 1997, Volume: 11, Issue:1 Topics: Acute Disease; Adenosine Triphosphate; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blast Crisis; Cyclosporine; Daunorubicin; Flow Cytometry; Humans; Leukemia, Myeloid; Potassium Cyanide; RNA, Messenger; Tumor Cells, Cultured	1997
Chemosensitization and drug accumulation effects of VX-710, verapamil, cyclosporin A, MS-209 and GF120918 in multidrug resistant HL60/ADR cells expressing the multidrug resistance-associated protein MRP. Anti-cancer drugs, 1997, Volume: 8, Issue:2 Topics: Acridines; Affinity Labels; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Cyclosporine; Daunorubicin; Doxorubicin; Drug Resistance, Multiple; Etoposide; Fluoresceins; HL-60 Cells; Humans; Isoquinolines; Multidrug Resistance-Associated Proteins; Piperidines; Pyridines; Quinolines; Tetrahydroisoquinolines; Tritium; Verapamil; Vincristine	1997
Relationship between expression level of P-glycoprotein and daunorubicin transport in LLC-PK1 cells transfected with human MDR1 gene. Biochemical pharmacology, 1997, Mar-07, Volume: 53, Issue:5 Topics: Animals; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cyclosporine; Daunorubicin; Dose-Response Relationship, Drug; Humans; LLC-PK1 Cells; Swine; Transfection	1997
Isolation and characterization of daunorubicin-resistant AML-2 sublines. Molecules and cells, 1997, Apr-30, Volume: 7, Issue:2 Topics: Adenosine Triphosphate; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Cell Separation; Cyanides; Cyclosporine; Daunorubicin; DNA Primers; Drug Resistance, Multiple; Humans; Leukemia, Myeloid, Acute; Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured	1997
Expression of c-Kit and functional drug efflux are correlated in de novo acute myeloid leukaemia. Leukemia, 1997, Volume: 11, Issue:11 Topics: Acute Disease; Antimetabolites, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Daunorubicin; Drug Resistance, Multiple; Fluorescent Antibody Technique, Indirect; Humans; Immunosuppressive Agents; Leukemia, Myeloid; Phenotype; Proto-Oncogene Proteins c-kit; Rhodamine 123; Rhodamines; Tumor Cells, Cultured	1997
Effect on cell kill of addition of multidrug resistance modifiers cyclosporin A and PSC 833 to cytotoxic agents in acute myeloid leukaemia. Leukemia research, 1997, Volume: 21, Issue:9 Topics: Acute Disease; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Survival; Coloring Agents; Cyclosporine; Cyclosporins; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Drug Synergism; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured	1997
The ability of verapamil to restore intracellular accumulation of anthracyclines in multidrug resistant cells depends on the kinetics of their uptake. European journal of pharmacology, 1998, Feb-19, Volume: 343, Issue:2-3 Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Daunorubicin; Doxorubicin; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Humans; Idarubicin; Leukemia; Tumor Cells, Cultured; Verapamil	1998
[Detection of multidrug resistance in patients with leukemia by using flow cytometry and RNA in situ hybridization]. Zhonghua nei ke za zhi, 1996, Volume: 35, Issue:9 Topics: Adult; Cyclosporine; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Flow Cytometry; Gene Expression; Genes, MDR; Humans; Immunosuppressive Agents; In Situ Hybridization; Leukemia, Myeloid, Accelerated Phase; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured	1996
Functional intracellular P-glycoprotein. International journal of cancer, 1998, Jun-10, Volume: 76, Issue:6 Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; Cell Line; Cyclosporine; Daunorubicin; Drug Resistance	1998
The modulating effect of PSC 833, cyclosporin A, verapamil and genistein on in vitro cytotoxicity and intracellular content of daunorubicin in childhood acute lymphoblastic leukemia. Leukemia, 1998, Volume: 12, Issue:6 Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Cell Survival; Cyclosporine; Cyclosporins; Daunorubicin; Drug Resistance, Neoplasm; Genistein; Humans; In Vitro Techniques; Multidrug Resistance-Associated Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Verapamil	1998
[The relationship between multi-drug resistance gene expression and drug resistance of ovarian carcinoma]. Zhonghua fu chan ke za zhi, 1997, Volume: 32, Issue:8 Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Cyclosporine; Daunorubicin; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Genes, MDR; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Ovarian Neoplasms; Random Allocation; Tumor Cells, Cultured; Vincristine	1997
Estimation of drug resistance by flow cytometry. Methods in molecular biology (Clifton, N.J.), 1998, Volume: 91 Topics: 3T3 Cells; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Daunorubicin; Drug Resistance, Multiple; Flow Cytometry; Genistein; Leukemia L5178; Mice; Probenecid; Recombinant Proteins; Rhodamine 123; Rhodamines; Transfection; Tumor Cells, Cultured; Verapamil	1998
Influence of SDZ-PSC833 on daunorubicin intracellular accumulation in bone marrow specimens from patients with acute myeloid leukaemia. British journal of haematology, 1998, Volume: 103, Issue:2 Topics: Acute Disease; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Marrow; Cyclosporine; Cyclosporins; Daunorubicin; Drug Interactions; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Immunosuppressive Agents; Leukemia, Myeloid; Tumor Cells, Cultured	1998
[Retardation of human drug-resistant HL-60 cell in G1 phase and induction of sensitive cell to apoptosis by cyclosporine A]. Yao xue xue bao = Acta pharmaceutica Sinica, 1996, Volume: 31, Issue:10 Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Division; Cyclosporine; Daunorubicin; Drug Resistance, Neoplasm; G1 Phase; Harringtonines; HL-60 Cells; Humans	1996
Cellular uptake and antiproliferative effects of therapeutic concentrations of idarubicin or daunorubicin and their alcohol metabolites, with or without cyclosporin A, in MDR1+ human leukemic cells. Leukemia & lymphoma, 1999, Volume: 33, Issue:5-6 Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Division; Cyclosporine; Daunorubicin; Drug Resistance, Multiple; Drug Therapy, Combination; Humans; Idarubicin; Immunosuppressive Agents; Leukemia; Tumor Cells, Cultured	1999
A new in vivo method to study P-glycoprotein transport in tumors and the blood-brain barrier. Cancer research, 1999, May-15, Volume: 59, Issue:10 Topics: Animals; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain Chemistry; Calcium Channel Blockers; Carcinoma, Small Cell; Cyclosporine; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Lung Neoplasms; Male; Metabolic Clearance Rate; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms; Rats; Rats, Nude; Recombinant Fusion Proteins; Tissue Distribution; Tumor Cells, Cultured; Verapamil	1999
Anti-psychotic drugs reverse multidrug resistance of tumor cell lines and human AML cells ex-vivo. Cancer letters, 1999, May-03, Volume: 139, Issue:1 Topics: Antipsychotic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Daunorubicin; Drug Interactions; Drug Resistance, Multiple; Enzyme Inhibitors; Humans; Leukemia, Myeloid; Rhodamine 123; Tumor Cells, Cultured	1999
Comparison of P-glycoprotein expression and function with in vitro sensitivity to anthracyclines in AML. Advances in experimental medicine and biology, 1999, Volume: 457 Topics: Acridines; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blast Crisis; Bone Marrow; Cell Survival; Cyclosporine; Daunorubicin; Gene Expression Regulation, Neoplastic; Humans; Isoquinolines; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Recurrence; Tetrahydroisoquinolines; Tumor Cells, Cultured	1999
Reproducible flow cytometric methodology for measuring multidrug resistance in leukaemic blasts. Advances in experimental medicine and biology, 1999, Volume: 457 Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Blast Crisis; Bone Marrow Cells; Cyclosporine; Cyclosporins; Daunorubicin; Drug Resistance, Multiple; Flow Cytometry; Genes, MDR; Humans; Leukemia, Myeloid, Acute; Multidrug Resistance-Associated Proteins; Reproducibility of Results	1999
Magnetic resonance spectroscopy of cellular lipid extracts from sensitive, resistant and reverting K562 cells and flow cytometry for investigating the P-glycoprotein function in resistance reversion. NMR in biomedicine, 2000, Volume: 13, Issue:2 Topics: Adenine Nucleotides; Amino Acids; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Division; Cyclosporine; Daunorubicin; Doxorubicin; Drug Resistance, Multiple; Flow Cytometry; Humans; K562 Cells; Magnetic Resonance Spectroscopy; Phospholipids	2000
MDR3 P-glycoprotein, a phosphatidylcholine translocase, transports several cytotoxic drugs and directly interacts with drugs as judged by interference with nucleotide trapping. The Journal of biological chemistry, 2000, Aug-04, Volume: 275, Issue:31 Topics: Adenosine Triphosphate; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Biological Transport; Cell Polarity; Cells, Cultured; Cyclosporine; Cyclosporins; Cytotoxins; Daunorubicin; Digoxin; Epithelial Cells; Humans; Ivermectin; Kidney; Paclitaxel; Pharmaceutical Preparations; Phosphatidylcholines; Recombinant Proteins; Spodoptera; Swine; Verapamil; Vinblastine	2000
Altered activity of MDR-reversing agents on KB3-1 cells transfected with Gly(185)-->Val human P-glycoprotein. International journal of oncology, 2000, Volume: 17, Issue:3 Topics: Adenosine Triphosphatases; Amino Acid Substitution; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Calcium Channel Blockers; Carcinoma, Squamous Cell; Colchicine; Cyclosporine; Cyclosporins; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Neoplasm Proteins; Paclitaxel; Point Mutation; Structure-Activity Relationship; Transfection; Tumor Cells, Cultured; Verapamil; Vinblastine	2000
Bullous acral erythema and concomitant pigmentation on the face and occluded skin. Journal of the European Academy of Dermatology and Venereology : JEADV, 2000, Volume: 14, Issue:2 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclosporine; Cytarabine; Daunorubicin; Drug Eruptions; Erythema; Female; Hand Dermatoses; Humans; Hyperpigmentation; Leukemia, Myeloid; Skin Diseases, Vesiculobullous	2000
Structure-activity relationship of P-glycoprotein substrates and modifiers. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2000, Volume: 12, Issue:1 Topics: Adenosine Triphosphatases; Amiodarone; Amitriptyline; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; CHO Cells; Colchicine; Cricetinae; Cyclosporine; Daunorubicin; Diltiazem; Kinetics; Micelles; Progesterone; Propranolol; Structure-Activity Relationship; Verapamil; Vinblastine	2000
Cyclosporin increases cellular idarubicin and idarubicinol concentrations in relapsed or refractory AML mainly due to reduced systemic clearance. Leukemia, 2001, Volume: 15, Issue:1 Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclosporine; Daunorubicin; Female; Humans; Idarubicin; Immunosuppressive Agents; Leukemia, Myeloid; Male; Middle Aged; Pilot Projects; Prospective Studies; Recurrence	2001
Intracellular P-gp contributes to functional drug efflux and resistance in acute myeloid leukaemia. Leukemia research, 2001, Volume: 25, Issue:5 Topics: Acute Disease; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Cell Death; Cell Survival; Cyclosporine; Daunorubicin; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance, Multiple; Flow Cytometry; HL-60 Cells; Humans; K562 Cells; Leukemia, Myeloid; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; RNA, Messenger; Vault Ribonucleoprotein Particles; Verapamil	2001
Effect of P-glycoprotein modulators on the human extraneuronal monoamine transporter. European journal of pharmacology, 2001, Jun-22, Volume: 422, Issue:1-3 Topics: 1-Methyl-4-phenylpyridinium; Arginine; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Carrier Proteins; Cations; Cell Line; Cyclosporine; Daunorubicin; Dose-Response Relationship, Drug; Histidine; Humans; Organic Cation Transport Proteins; Rhodamine 123; Time Factors; Tritium; Tyramine; Verapamil; Vinblastine	2001
[In vitro reversal effect of cyclosporin A in combination with cytokines on multidrug resistant cell line K562/A02]. Zhonghua yi xue za zhi, 1999, Volume: 79, Issue:3 Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Cytokines; Daunorubicin; Drug Interactions; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Immunosuppressive Agents; Interferon-alpha; K562 Cells	1999
Hematopoietic cell transplantation beyond first remission. Leukemia, 2002, Volume: 16, Issue:2 Topics: Acute Disease; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Comorbidity; Cyclosporine; Cytarabine; Daunorubicin; Disease-Free Survival; Follow-Up Studies; Graft Survival; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Nuclear Family; Prospective Studies; Randomized Controlled Trials as Topic; Remission Induction; Salvage Therapy; Survival Rate; Tissue Donors; Transplantation, Homologous; Treatment Outcome; Vidarabine	2002
Low level of mitochondrial deoxyguanosine kinase is the dominant factor in acquired resistance to 9-beta-D-arabinofuranosylguanine cytotoxicity. Biochemical and biophysical research communications, 2002, May-24, Volume: 293, Issue:5 Topics: Anthracyclines; Antineoplastic Agents; Arabinonucleosides; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cells, Cultured; Cyclosporine; Daunorubicin; Deoxycytidine Kinase; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Electrophoresis, Polyacrylamide Gel; Flow Cytometry; Fluoresceins; Humans; Mitochondria; Nucleosides; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured	2002
Influence of chemosensitizers on resistance mechanisms in daunorubicin-resistant Ehrlich ascites tumour cells. Cancer chemotherapy and pharmacology, 2002, Volume: 49, Issue:6 Topics: Animals; Antigens, Neoplasm; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Carcinoma, Ehrlich Tumor; Cyclosporine; Daunorubicin; DNA Primers; DNA Topoisomerases, Type II; DNA-Binding Proteins; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Verapamil; Vincristine	2002
Acute myelogenous leukemia following treatment with cyclosporin A in a nephrotic patient. Internal medicine (Tokyo, Japan), 2002, Volume: 41, Issue:9 Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cyclosporine; Cytarabine; Daunorubicin; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Male; Nephrotic Syndrome; Treatment Outcome	2002
Different effects of metabolic inhibitors and cyclosporin A on daunorubicin transport in leukemia cells from patients with AML. Leukemia research, 2003, Volume: 27, Issue:2 Topics: Acute Disease; Adult; Aged; Aged, 80 and over; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Cyclosporine; Daunorubicin; Enzyme Inhibitors; Female; Humans; Iodoacetates; Leukemia, Myeloid; Male; Middle Aged; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; RNA, Messenger; Sodium Azide; Vault Ribonucleoprotein Particles	2003
Pumping of drugs by P-glycoprotein: a two-step process? The Journal of pharmacology and experimental therapeutics, 2003, Volume: 307, Issue:3 Topics: Algorithms; Animals; Anti-Bacterial Agents; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Calcium Channel Blockers; Carcinoma, Ehrlich Tumor; Cell Line, Tumor; Cyclosporine; Daunorubicin; Fluoresceins; Humans; Immunosuppressive Agents; Kinetics; Models, Biological; Pharmaceutical Preparations; Quinolines; Verapamil; Vinblastine	2003
P-glycoprotein inhibitors modulate accumulation and efflux of xenobiotics in extra and intracellular Toxoplasma gondii. Molecular and biochemical parasitology, 2004, Volume: 134, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; Biological Transport, Active; Carbocyanines; Cell Line; Cyclosporine; Daunorubicin; Drug Resistance, Multiple; Fluorescent Dyes; Humans; Membrane Transport Proteins; Protozoan Proteins; Toxoplasma; Vacuoles; Verapamil; Xenobiotics	2004
Jatrophane diterpenes as modulators of multidrug resistance. Advances of structure-activity relationships and discovery of the potent lead pepluanin A. Journal of medicinal chemistry, 2004, Feb-12, Volume: 47, Issue:4 Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Line, Tumor; Cyclosporine; Daunorubicin; Diterpenes; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Magnetic Resonance Spectroscopy; Nicotinic Acids; Structure-Activity Relationship	2004
[Inducing effect of cyclosporin A on apoptosis of multidrug resistant cell lines HR20 and HT9]. Ai zheng = Aizheng = Chinese journal of cancer, 2004, Volume: 23, Issue:12 Topics: Apoptosis; Apoptosis Regulatory Proteins; Caspase 3; Caspases; Cell Nucleus; Cyclosporine; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; HL-60 Cells; Humans; Proteins; Vincristine	2004
Effects of daunorubicin, mitomycin C, azathioprine and cyclosporin A on human retinal pigmented epithelial, corneal endothelial and conjunctival cell lines. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2006, Volume: 244, Issue:3 Topics: Antimetabolites; Azathioprine; Cell Count; Cell Line; Cell Proliferation; Conjunctiva; Cyclosporine; Daunorubicin; Endothelium, Corneal; Epithelial Cells; Fluoresceins; Humans; Immunosuppressive Agents; Mitomycin; Pigment Epithelium of Eye; Propidium	2006
Anthracyclines, proteasome activity and multi-drug-resistance. BMC cancer, 2005, Sep-13, Volume: 5 Topics: Anthracyclines; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Chymotrypsin; Cyclosporine; Cysteine Proteinase Inhibitors; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Leupeptins; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Transfection	2005
Rapid collapse of mitochondrial transmembrane potential in HL-60 cells and isolated mitochondria treated with anti-tumor 1,4-anthracenediones. Anti-cancer drugs, 2005, Volume: 16, Issue:9 Topics: Alamethicin; Animals; Anthraquinones; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bongkrekic Acid; Calcium Chloride; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cyclosporine; Cysteine Proteinase Inhibitors; Daunorubicin; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Female; Gramicidin; HL-60 Cells; Humans; Intracellular Membranes; Ion Channels; Membrane Potentials; Mice; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitoxantrone; Ruthenium Red; Staurosporine; Ubiquinone	2005
Post-transplantation lymphoproliferative disorder of recipient origin in a boy with acute T-cell leukemia with detection of B-cell clonality 3 months before stem cell transplantation. Haematologica, 2005, Volume: 90 Suppl Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; B-Lymphocytes; Child; Clone Cells; Combined Modality Therapy; Cyclophosphamide; Cyclosporine; Cytarabine; Daunorubicin; Dexamethasone; Epstein-Barr Virus Infections; Etoposide; Fatal Outcome; Glucocorticoids; Graft vs Host Disease; Herpesvirus 4, Human; Humans; Immunosuppressive Agents; Leukemia-Lymphoma, Adult T-Cell; Lymphocyte Transfusion; Lymphoproliferative Disorders; Male; Postoperative Complications; Prednisolone; Rituximab; Time Factors; Transplantation Chimera; Transplantation Conditioning; Vincristine; Virus Activation; Whole-Body Irradiation	2005
Complete inhibition of P-glycoprotein by simultaneous treatment with a distinct class of modulators and the UIC2 monoclonal antibody. The Journal of pharmacology and experimental therapeutics, 2007, Volume: 320, Issue:1 Topics: Animals; Antibodies, Monoclonal; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Cyclosporins; Daunorubicin; Fluoresceins; Humans; Mice; NIH 3T3 Cells; Vinblastine	2007
Species differences of inhibitory effects on P-glycoprotein-mediated drug transport. Journal of pharmaceutical sciences, 2007, Volume: 96, Issue:6 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cyclosporine; Daunorubicin; Digoxin; Dogs; Dose-Response Relationship, Drug; Humans; Mice; Quinidine; Rats; Species Specificity; Verapamil	2007
Interactions of cyclosporin a with breast cancer resistance protein. Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:4 Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line; Cell Membrane; Cell Membrane Permeability; Cyclosporine; Daunorubicin; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Estrone; Female; Humans; Immunosuppressive Agents; Methotrexate; Mutation; Neoplasm Proteins; Transfection	2007
Modification of multidrug resistance of tumor cells by ionizing radiation. Cancer chemotherapy and pharmacology, 2008, Volume: 61, Issue:1 Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Cell Count; Cell Line, Tumor; Combined Modality Therapy; Cyclosporine; Daunorubicin; Dose-Response Relationship, Radiation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Laryngeal Neoplasms; Paclitaxel; Radiation, Ionizing; Reactive Oxygen Species; Rhodamine 123; Time Factors; Vincristine	2008
Inhibitory effects of ginsenosides and their hydrolyzed metabolites on daunorubicin transport in KB-C2 cells. Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:10 Topics: Adenosine Triphosphatases; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Calcium Channel Blockers; Cell Membrane; Colchicine; Cyclosporine; Dammaranes; Daunorubicin; Drug Resistance, Neoplasm; Ginsenosides; Humans; Hydrolysis; KB Cells; Multidrug Resistance-Associated Proteins; Structure-Activity Relationship; Triterpenes; Verapamil	2007
Selective modulation of P-glycoprotein activity by steroidal saponines from Paris polyphylla. Fitoterapia, 2009, Volume: 80, Issue:1 Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cyclosporine; Daunorubicin; Diosgenin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Ecdysteroids; Ecdysterone; Humans; Immunosuppressive Agents; K562 Cells; Leukemia; Magnoliopsida; Membrane Transport Modulators; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Plant Extracts; Rhizome; Saponins; Spirostans; Steroids	2009
Impact of novel MDR modulators on human cancer cells: reversal activities and induction studies. Pharmaceutical research, 2009, Volume: 26, Issue:1 Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Northern; Blotting, Western; Cell Line, Tumor; Cyclosporine; Data Interpretation, Statistical; Daunorubicin; Flow Cytometry; Fluorescent Dyes; Humans; Immunosuppressive Agents; Membrane Transport Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger	2009
Iodination increases the activity of verapamil derivatives in reversing PGP multidrug resistance. Anticancer research, 2010, Volume: 30, Issue:7 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Cycle; Cyclosporine; Daunorubicin; Drug Resistance, Neoplasm; Drug Synergism; Humans; K562 Cells; Male; Myocytes, Cardiac; Rats; Rats, Wistar; Rhodamine 123; Verapamil	2010
Pgp inhibition by UIC2 antibody can be followed in vitro by using tumor-diagnostic radiotracers, 99mTc-MIBI and 18FDG. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2010, Dec-23, Volume: 41, Issue:5 Topics: Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cyclosporine; Daunorubicin; Drug Resistance, Multiple; Female; Fluorodeoxyglucose F18; Glucose; Humans; Ovarian Neoplasms; Paclitaxel; Protein Binding; Rhodamine 123; Technetium Tc 99m Sestamibi; Tumor Cells, Cultured	2010
Micellar electrokinetic chromatographic analysis for in vitro accumulation of anthracyclines enhanced by inhibitors of cell membrane transporter-proteins in cancer cells. Biomedical chromatography : BMC, 2011, Volume: 25, Issue:10 Topics: Biological Transport, Active; Cell Line, Tumor; Cellular Structures; Chromatography, Micellar Electrokinetic Capillary; Cyclosporine; Daunorubicin; Humans; Membrane Transport Modulators; Membrane Transport Proteins; Probenecid; Verapamil	2011
Flow cytometry-based assessment of mitoxantrone efflux from leukemic blasts varies with response to induction chemotherapy in acute myeloid leukemia. Cytometry. Part B, Clinical cytometry, 2012, Volume: 82, Issue:5 Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cyclosporine; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Female; Flow Cytometry; Humans; Induction Chemotherapy; Karyotype; Leukemia, Myeloid, Acute; Lymphoid Progenitor Cells; Male; Middle Aged; Mitoxantrone; Neoplasm Proteins; Statistics, Nonparametric; Young Adult	2012
Discrimination of Multidrug Resistance in Cancer Cells Achieved Using Single-Cell Analysis. Methods in molecular biology (Clifton, N.J.), 2023, Volume: 2689 Topics: Biological Transport; Coloring Agents; Cyclosporine; Daunorubicin; Drug Resistance, Multiple; Female; Humans; Ovarian Neoplasms; Single-Cell Analysis	2023