Compounds > daunorubicin
Page last updated: 2024-08-23

daunorubicin and aclarubicin

daunorubicin has been researched along with aclarubicin in 130 studies

Research

Studies (130)

TimeframeStudies, this research(%)All Research%
pre-199061 (46.92)18.7374
1990's54 (41.54)18.2507
2000's10 (7.69)29.6817
2010's5 (3.85)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Binderup, L; Bols, M; Hansen, J; Rasmussen, P1
Berscheid, HG; Böttger, D; Hermentin, P; Hoffmann, D; Kraemer, HP; Sedlacek, HH1
Umezawa, H2
Matsushima, T; Sawamura, M; Sugimura, T; Umezawa, K1
Bourut, C; Dantchev, D; Hayat, M; Mathé, G; Paintrand, M; Slioussartchouk, V1
Hirano, S; Hori, S; Inui, T; Ishizuka, M; Oki, T; Shirai, M; Takeuchi, T; Tsukagoshi, S; Umezawa, H1
Fukushima, T; Nakamura, T; Ueda, T1
Araki, Y; Gomita, Y; Shinozawa, S1
Garnier-Suillerot, A; Tarasiuk, J1
Aoki, N; Goto, Y; Kanemoto, N1
Delius, M; Gambihler, S1
Matsumoto, H; Metori, K; Mineo, S; Satoh, T; Tanaka, T1
Demant, EJ; Friche, E; Hansen, HH; Jensen, PB; Jensen, PS; Sehested, M; Sørensen, BS; Vindeløv, L; Wassermann, K; Westergaard, O1
Hironaka, T; Horiike, S; Kashima, K; Misawa, S; Nakagawa, H; Nishigaki, H; Shizumi, Y; Takashima, T; Tanaka, S; Taniwaki, M1
Reinert, KE2
Izumi, H; Shirai, M; Yamagami, T1
Diatchkovskaya, RF; Ganieva, LKh; Konovalova, NP; Lapshin, IM; Shapiro, AB; Volkova, LM1
Gotohda, Y; Iwasaki, H; Kakinoki, Y; Katagiri, M; Kobayashi, T; Miyazaki, T; Morioka, M; Sakurada, K; Tanaka, M1
Dahle, M; Marquardt, H; Radenz, G; Schaefer, A; Steinheider, G1
Boesen, AM; Brincker, H; Christensen, BE; Drivsholm, A; Ellegaard, J; Hansen, OP; Hippe, E; Jans, H; Jensen, KB; Pedersen-Bjergaard, J1
Akazawa, K; Asano, Y; Harada, M; Morioka, E; Niho, Y; Okamura, S; Shibuya, T1
Frezard, F; Garnier-Suillerot, A1
Arai, N; Shirai, T; Umeda, M1
Sazuka, Y; Takino, Y; Tanizawa, H1
Demant, EJ; Hansen, HH; Jensen, PB; Roed, H; Sehested, M; Skovsgaard, T; Vindeløv, L1
Kyo, T; Maehama, S1
Akahoshi, Y; Asou, N; Fujimoto, K; Fukuda, S; Ishimaru, S; Kawano, F; Murai, C; Sawatari, T; Taen, A; Takatsuki, K1
Maruyama, Y; Nagata, K; Nakamura, S; Onozawa, Y; Sakamaki, H; Yahara, Y1
Bogdanić, V; Jaksić, B; Labar, B; Malesević, M; Minigo, H; Mrsić, M; Nemet, D1
Asano, Y; Hirota, Y; Morioka, E; Niho, Y; Okamura, S; Shibuya, T1
Raymond, V; Young, CW1
Boulé, D; Fourcade, A; Lampidis, TJ; Tapiero, H; Trincal, G1
Burres, NS; Myers, MT; Sartorelli, AC1
Nwankwoala, RN; West, WL1
Dohy, H; Kyo, T1
Chaires, JB; Crothers, DM; Dattagupta, N; Fritzsche, H; Schlessinger, FB; Wähnert, U1
Fink, FM; Gadner, H; Grümayer, ER; Kardos, G; Revesz, T; Schuler, D2
Fukutani, H; Kataoka, T; Takeyama, H; Watanabe, E; Yano, K1
Kadomoto, Y; Kajihara, H; Tahara, E; Yamahara, M; Yokozaki, H1
Kimura, I; Kitani, T; Masaoka, T; Meguro, S; Nagai, K; Ogawa, M; Ohnoshi, T; Sampi, K; Wakui, A; Yamada, K1
Aoki, N; Imai, Y; Murohashi, I; Nara, N; Tanikawa, S; Yamashita, Y1
Björkholm, M; Killander, A1
Ando, S; Kagawa, D; Nakamura, T; Sasada, M; Uchino, H; Ueda, T1
Marquardt, H; Steinheider, G; Westendorf, J1
Ehninger, G; Freund, M; Heil, G; Hoelzer, D; Kurrle, E; Link, H; Mitrou, PS1
Skovsgaard, T1
Horiuchi, A; Kawagoe, H; Kitani, T; Masaoka, T; Nagai, K; Oguma, S; Shibata, H; Yasunaga, K; Yonezawa, T1
Marie, JP; Thevenin, D; Zittoun, R1
Abdella, BR; Fisher, J; McLane, KE1
Asou, N; Kawano, F; Matsuoka, Y; Tajima, H; Takatsuki, K1
Kraemer, HP; Röthig, HJ; Sedlacek, HH1
Kurita, S; Masaoka, T; Ogawa, N; Ota, K; Uzuka, Y; Yamada, K1
Crooke, ST; DuVernay, VH; Mong, S; Strong, JE1
El-Hage, AN; Ferrans, VJ; Herman, EH; Kaliner, M; Kawanami, O; Riegel, EA1
Kawamura, S; Maekawa, I; Miyake, T; Sasaki, H1
Tanaka, N1
Jasmin, C; Maral, R; Marzin, D; Mathe, G1
Becvar, JE; Fisher, J; Ramakrishnan, K1
Brown, BJ; Marsh, JC; Nierenburg, MM1
Kobayashi, M; Tahara, T1
Hattori, M; Hayashi, Y; Honda, T; Sampi, K1
Erttmann, R1
Applefeld, MM; Bulkley, BH; Grochow, LB; Mader, LC; Taylor, AL; Wiernik, PH1
Bachur, NR; Bhatnagar, R; Egorin, MJ; Ito, Y; Nakazawa, H; Redwood, SM; Riggs, CE1
Tatsuta, K1
Brincker, H; Drivsholm, A; Ellegaard, J; Freund, L; Jensen, KB; Jensen, MK; Nissen, NI; Pedersen-Bjergaard, J1
Bachur, NR; Pan, SS; Pedersen, L1
Crooke, ST; Loth, H; Seeber, S1
Oka, S; Oki, T; Takeuchi, T; Umezawa, H1
Cradock, JC; Flora, KP; Poochikian, GK1
Hamami, T; Haruyama, H; Ijichi, H; Isemura, T; Nakagawa, M; Nakajima, Y; Shimazaki, C; Ura, Y1
Blum, RH; Muggia, FM; Wernz, JC1
Baurain, R; Trouet, A; Zenebergh, A1
Berg, G; Evdokimov, IuM; Salianov, VI1
Hamami, T; Haruyama, H; Ijichi, H; Isemura, T; Katsume, H; Nakagawa, M; Nakanishi, S; Nisio, A; Shimazaki, C1
Adachi, T; Endo, Y; Fujimoto, S; Hara, M; Kimura, I; Kitajima, K; Kohi, F; Lai, M; Oda, Y; Ohmoto, E; Sanada, H; Takahashi, I; Takaoka, K; Tokioka, M; Uchida, K; Watanabe, S; Yorimitsu, S1
Myers, CE; Ozols, RF; Young, RC1
Arima, N; Hidaka, S; Matsumoto, T; Matsushita, K; Ohtsubo, H; Tanaka, H1
Clausen, N; Ellegaard, J; Hokland, P; Langkjer, ST; Nørgaard, JM; Palshof, T1
den Boer, ML; Huismans, DR; Klumper, E; Loonen, AH; Pieters, R; Veerman, AJ1
Lampidis, TJ; Nguyen-Ba, G; Tapiero, H1
Nishimura, S; Saito, H; Sakurai, T; Sasaki, Y; Shibu, T; Sukekawa, H; Takeishi, Y; Tomoike, H1
Coley, HM; Twentyman, PR; Workman, P1
Hatake, K; Sakamoto, K; Wakabayashi, I; Yoshimoto, S1
Amaki, I; Kawashima, K; Kimura, K; Maekawa, T; Masaoka, T; Nagura, E; Ohta, K; Takaku, F; Uchino, H; Yamada, K1
Kaletin, GI; Pirogova, NA; Volkova, MA1
Perilov, AA; Poddubnaia, IV1
Dorn, A; Graf, N; Pees, HW1
Abe, Y; Hatanaka, T; Ito, T; Kamiya, O; Nagata, K; Ohara, K; Ono, Y; Saito, M1
Ikeda, K; Kubota, Y; Murata, M; Nagai, M; Ohnishi, H; Sasaki, K; Takahara, J; Tanaka, T; Taoka, T; Tasaka, T1
Hirakawa, K; Horiike, S; Kaneko, H; Kashima, K; Misawa, S; Nakai, H; Nakao, M; Taniwaki, M; Ueda, Y1
Elonen, E; Jokipii, A; Lautenschlager, I; Lyytikäinen, O; Ruutu, P; Tiittanen, L1
Amley, J; Chan, PK; Koller, CA; Qi, Y1
Harding, MM; Prakash, AS; Shelton, CJ1
Ezaki, K; Hirano, M; Ino, T; Miyazaki, H; Okamoto, M; Tsuzuki, M1
Clausen, N; Hokland, P; Langkjer, ST; Nørgaard, JM; Palshof, T; Pedersen, B1
Bartoshevich, IuE; Efremenkova, OV; Makhova, EV; Vasil'eva, SV1
Clausen, OP; De Angelis, P; Lehne, G; Rugstad, HE2
Boesen, AM; de Nully Brown, P; Grønbaek, K; Hansen, OP; Hippe, E; Hoffmann, T; Jensen, MK; Pedersen-Bjergaard, J; Storm, HH; Thorling, K1
Horikawa, K; Okada, Y; Sano, M1
Ezaki, K; Hirano, M; Ino, T; Kojima, H; Maruyama, F; Matsui, T; Miyazaki, H; Nomura, T; Okamoto, M; Tsuzuki, M; Yamaguchi, T1
Rajgarhia, VB; Strohl, WR1
Hanada, R; Hongo, T; Horikoshi, Y; Sakurai, M; Yajima, S1
Hakala, J; Mäntsälä, P; Skurnik, M; Torkkell, S; Ylihonko, K1
Tsuboi, M; Utsuno, K1
Asami, K; Eguchi, H; Fujimoto, T; Gushiken, T; Hirota, T; Hyakuna, N; Imaizumi, M; Kamitamari, A; Katano, N; Kawakami, K; Koizumi, S; Komatu, K; Miyake, M; Mugishima, H; Nakadate, N; Nishikawa, K; Shirahata, A; Takitani, K; Tsurasawa, M; Yanase, T1
Bukh, A; Clausen, N; Hokland, P; Langkjer, ST; Nørgaard, JM; Palshof, T1
Amemiya, Y; Furukawa, Y; Hoshino, M; Imagawa, S; Izumi, T; Kawano, C; Kirito, K; Komatsu, N; Kuribara, R; Miura, Y; Miyazato, A; Muroi, K; Omine, K; Otsuki, T; Shimizu, R; Suzuki, T; Tabata, M; Takahashi, H; Takatoku, M; Terui, Y; Tomizuka, H; Toshima, M; Tsunoda, J; Uchida, M; Yoshida, M1
Almqvist, A; Elonen, E; Hänninen, A; Jansson, SE; Järventie, G; Koistinen, P; Koivunen, E; Lahtinen, R; Lehtinen, M; Nousiainen, T; Pelliniemi, TT; Rajamäki, A; Remes, K; Ruutu, T; Timonen, T; Vilpo, J; Volin, L1
Hokland, P; Kristensen, JS; Nørgaard, JM; Olesen, G; Pedersen, B1
Bauer, E; Clark, M; Gieseler, F; Nuessler, V; Valsamas, S1
Hokland, P; Langkjer, ST; Nørgaard, JM; Palshof, T; Pedersen, B1
Monneret, C1
Bendix, K; Hokland, P; Kjeldsen, E; Kristensen, JS; Meyer, K; Nørgaard, JM; Olesen, G; Olesen, LH; Pedersen, B1
Björeman, M; Björkholm, M; Gahrton, G; Grimfors, G; Gruber, A; Hast, R; Killander, A; Lerner, R; Liliemark, J; Mattson, S; Oberg, G; Paul, C; Simonsson, B; Stalfelt, AM; Stenke, L; Tidefelt, U; Udén, AM1
Boldt, S; Dartsch, DC; Kolch, W; Marquardt, H; Schaefer, A1
Dragojew, S; Jóźwiak, Z; Kania, K1
Franco, A; Lehmann, M; Reguly, ML; Rodrigues de Andrade, HH; Vilar, Kde S1
Miura, T; Muraoka, S1
Khosla, C; Lee, TS; Tang, Y1
Chen, FY; Gu, CH; Ouyang, RR; Teng, Y; Wang, T; Zhong, H1
de Jong, J; Neefjes, J; Pang, B; Qiao, X; Wessels, LF1
Ding, C; Jiao, W; Li, X; Liu, L; Qu, Q; Wu, D; Zhang, Y1
Ashizawa, M; Fujiwara, S; Hatano, K; Ito, S; Kanda, Y; Kawasaki, Y; Mashima, K; Minakata, D; Muroi, K; Nakano, H; Oh, I; Ohmine, K; Okazuka, K; Sato, K; Sugimoto, M; Suzuki, T; Umino, K; Yamamoto, C; Yamasaki, R1
Chen, Y; Hu, J; Liu, T; Yang, T; Yang, X; Zheng, J; Zheng, X; Zheng, Z1
Huang, Y; Liu, DD; Lv, TT; Xu, J; Yuan, GL; Zhou, XF1

Reviews

6 review(s) available for daunorubicin and aclarubicin

ArticleYear
Acute erythroleukemia with t(3;5) accompanied by hepatocellular carcinoma.
    International journal of hematology, 1991, Volume: 54, Issue:3

    Topics: Aclarubicin; Adolescent; Adult; Aged; Anemia, Refractory, with Excess of Blasts; Carcinoma, Hepatocellular; Child; Chromosomes, Human, Pair 3; Chromosomes, Human, Pair 5; Cytarabine; Daunorubicin; Doxorubicin; Female; Hepatectomy; Hepatitis B; Humans; Leukemia, Erythroblastic, Acute; Liver Neoplasms; Male; Middle Aged; Mitomycin; Neoplasm Recurrence, Local; Neoplasms, Multiple Primary; Prednisolone; Remission Induction; Translocation, Genetic

1991
[Chronic myelocytic leukemia following chemotherapy of acute promyelocytic leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1989, Volume: 30, Issue:11

    Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisolone; Remission Induction

1989
Clinical assessment of the structure-activity relationship of anthracyclines and related synthetic derivatives.
    Cancer treatment reports, 1986, Volume: 70, Issue:1

    Topics: Aclarubicin; Anthraquinones; Antibiotics, Antineoplastic; Breast Neoplasms; Carubicin; Cell Survival; Daunorubicin; Doxorubicin; Drug Evaluation; Epirubicin; Heart; Humans; Idarubicin; Leukemia; Menogaril; Mitoxantrone; Naphthacenes; Nogalamycin; Sarcoma; Structure-Activity Relationship

1986
Pharmacodynamic aspects of aclarubicin with special reference to daunorubicin and doxorubicin.
    European journal of haematology. Supplementum, 1987, Volume: 47

    Topics: Aclarubicin; Animals; Antibiotics, Antineoplastic; Cell Differentiation; Daunorubicin; Doxorubicin; Drug Resistance; Naphthacenes; Nucleic Acids

1987
The anthracycline antineoplastic drugs.
    The New England journal of medicine, 1981, Jul-16, Volume: 305, Issue:3

    Topics: Aclarubicin; Animals; Antibiotics, Antineoplastic; Breast Neoplasms; Carubicin; Daunorubicin; Doxorubicin; Female; Glycosides; Hodgkin Disease; Humans; Leukemia; Lung Neoplasms; Lymphoma; Naphthacenes; Ovarian Neoplasms; Sarcoma

1981
Recent developments in the field of antitumour anthracyclines.
    European journal of medicinal chemistry, 2001, Volume: 36, Issue:6

    Topics: Aclarubicin; Amino Acid Sequence; Animals; Anthracyclines; Antineoplastic Agents; Carubicin; Daunorubicin; Doxorubicin; Drug Resistance, Neoplasm; Humans; Neoplasms

2001

Trials

12 trial(s) available for daunorubicin and aclarubicin

ArticleYear
Aclarubicin plus cytosine arabinoside versus daunorubicin plus cytosine arabinoside in previously untreated patients with acute myeloid leukemia: a Danish national phase III trial. The Danish Society of Hematology Study Group on AML, Denmark.
    Leukemia, 1991, Volume: 5, Issue:6

    Topics: Aclarubicin; Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Chi-Square Distribution; Cytarabine; Daunorubicin; Denmark; Drug Administration Schedule; Etoposide; Humans; Leukemia, Myeloid, Acute; Middle Aged; Regression Analysis; Remission Induction; Survival Rate

1991
Aclarubicin in the treatment of de-novo acute myelocytic leukaemia.
    Bone marrow transplantation, 1989, Volume: 4 Suppl 3

    Topics: Aclarubicin; Adolescent; Adult; Bone Marrow Transplantation; Combined Modality Therapy; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Randomized Controlled Trials as Topic

1989
Aclacinomycin-A in the induction treatment of childhood acute myelogenous leukemia.
    Haematology and blood transfusion, 1987, Volume: 30

    Topics: Aclarubicin; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Clinical Trials as Topic; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Naphthacenes; Prospective Studies; Remission Induction

1987
Aclarubicin: experimental and clinical experience.
    Drugs under experimental and clinical research, 1985, Volume: 11, Issue:2

    Topics: Aclarubicin; Animals; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colony-Forming Units Assay; Cytarabine; Daunorubicin; Doxorubicin; Humans; Leukemia L1210; Leukemia, Monocytic, Acute; Naphthacenes

1985
[Results of follow-up studies on prognosis after immunotherapy with bestatin in acute nonlymphocytic leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:4 Pt 1

    Topics: Aclarubicin; Acute Disease; Adjuvants, Immunologic; Adolescent; Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Follow-Up Studies; Humans; Leucine; Leukemia; Mercaptopurine; Middle Aged; Naphthacenes; Prednisolone; Prognosis; Random Allocation

1986
Noninvasive identification of anthracycline cardiotoxicity: comparison of 123I-MIBG and 123I-BMIPP imaging.
    Annals of nuclear medicine, 1994, Volume: 8, Issue:3

    Topics: 3-Iodobenzylguanidine; Aclarubicin; Adult; Aged; Antibiotics, Antineoplastic; Daunorubicin; Doxorubicin; Echocardiography; Fatty Acids; Female; Heart; Humans; Iodine Radioisotopes; Iodobenzenes; Male; Middle Aged; Neoplasms; Radionuclide Imaging

1994
Nationwide randomized comparative study of daunorubicin and aclarubicin in combination with behenoyl cytosine arabinoside, 6-mercaptopurine, and prednisolone for previously untreated acute myeloid leukemia.
    Cancer chemotherapy and pharmacology, 1994, Volume: 34, Issue:1

    Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Male; Mercaptopurine; Middle Aged; Prednisolone; Prospective Studies; Survival Analysis

1994
Long-term survival and development of secondary malignancies in patients with acute myeloid leukemia treated with aclarubicin or daunorubicin plus cytosine arabinoside followed by intensive consolidation chemotherapy in a Danish national phase III trial.
    Leukemia, 1997, Volume: 11, Issue:1

    Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Age Factors; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Follow-Up Studies; Humans; Leukemia, Myeloid; Male; Middle Aged; Neoplasms, Second Primary; Recurrence; Remission Induction; Survival Rate; Survivors

1997
[Short-term intensive treatment for acute myelogenous leukemia (excluding M3 subtype) in adults].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1997, Volume: 38, Issue:3

    Topics: Aclarubicin; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Middle Aged; Mitoxantrone; Time Factors; Vinblastine; Vincristine

1997
[Treatment results of intermittent and cyclic regimen with ATRA and chemotherapy in childhood acute promyelocytic leukemia. Children's Cancer and Leukemia Study Group].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1997, Volume: 38, Issue:11

    Topics: Aclarubicin; Administration, Oral; Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Drug Administration Schedule; Female; Humans; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Prednisolone; Tretinoin; Vincristine

1997
Comparison between four and eight cycles of intensive chemotherapy in adult acute myeloid leukemia: a randomized trial of the Finnish Leukemia Group.
    Leukemia, 1998, Volume: 12, Issue:7

    Topics: Aclarubicin; Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Administration Schedule; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisolone; Prospective Studies; Remission Induction; Vincristine

1998
Long-term follow-up of patients >or=60 yr old with acute myeloid leukaemia treated with intensive chemotherapy.
    European journal of haematology, 2002, Volume: 68, Issue:6

    Topics: Aclarubicin; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Middle Aged; Survival Rate; Thioguanine; Time Factors

2002

Other Studies

112 other study(ies) available for daunorubicin and aclarubicin

ArticleYear
Inhibition of collagenase by aranciamycin and aranciamycin derivatives.
    Journal of medicinal chemistry, 1992, Jul-24, Volume: 35, Issue:15

    Topics: Animals; Anthracyclines; Antibiotics, Antineoplastic; Magnetic Resonance Spectroscopy; Microbial Collagenase; Pancreatic Elastase; Rats; Sarcoma, Experimental; Streptomyces; Trypsin Inhibitors; Tumor Cells, Cultured

1992
Structure-activity relationship of anthracyclines in vitro.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:1

    Topics: Animals; Antibiotics, Antineoplastic; Chemical Phenomena; Chemistry, Physical; Colonic Neoplasms; DNA; Humans; Leukemia L1210; Molecular Structure; Neoplasms; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured

1990
Recent advances in antitumor antibiotics.
    Antibiotics and chemotherapy, 1978, Volume: 23

    Topics: Aclarubicin; Animals; Anthraquinones; Antibiotics, Antineoplastic; Bleomycin; Daunorubicin; DNA; Glycosides; Humans; Neoplasms; Structure-Activity Relationship; Zinostatin

1978
Mutagenicity of aclacinomycin A and daunomycin derivatives.
    Cancer research, 1978, Volume: 38, Issue:6

    Topics: Aclarubicin; Antibiotics, Antineoplastic; Daunorubicin; Glycosides; Mutagens; Mutation; Naphthacenes; Salmonella typhimurium; Structure-Activity Relationship

1978
Electron microscopic studies of the heart and light microscopic studies of the skin after treatment of golden hamsters with adriamycin, detorubicin, AD-32, and aclacinomycin.
    Cancer treatment reports, 1979, Volume: 63, Issue:5

    Topics: Aclarubicin; Animals; Antibiotics, Antineoplastic; Cricetinae; Daunorubicin; Doxorubicin; Drug Administration Schedule; Heart; Leukemia L1210; Mesocricetus; Microscopy, Electron; Myocardium; Naphthacenes; Skin

1979
Antitumor activity of new anthracycline antibiotics, aclacinomycin-A and its analogs, and their toxicity.
    Gan, 1977, Volume: 68, Issue:5

    Topics: Aclarubicin; Animals; Anthraquinones; Antibiotics, Antineoplastic; Cricetinae; Daunorubicin; Doxorubicin; Electrocardiography; Glycosides; Heart; Leukemia L1210; Leukemia, Experimental; Lymphoma, Non-Hodgkin; Male; Mesocricetus; Mice; Mice, Inbred Strains; Sarcoma 180; Sarcoma, Experimental; Streptomyces

1977
[Pharmacokinetics and action mechanism of anthracyclines].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:4

    Topics: Aclarubicin; Acute Disease; Antibiotics, Antineoplastic; Daunorubicin; DNA; DNA Damage; DNA Replication; Doxorubicin; Humans; Leukemia, Myeloid

1992
[Effects of anthracycline drugs (aclarubicin, daunorubicin, doxorubicin, epirubicin, pirarubicin) on mouse acute toxicity and rat liver microsomal lipid peroxidation].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:6

    Topics: Aclarubicin; Animals; Antibiotics, Antineoplastic; Body Weight; Daunorubicin; Doxorubicin; Epirubicin; Lipid Peroxidation; Male; Mice; Mice, Inbred ICR; Microsomes, Liver; Mitochondria, Liver; Rats; Rats, Inbred Strains

1992
Thermodynamics of the anthracycline-nuclei interactions in drug-resistant and drug-sensitive K562 cells.
    Biochemical pharmacology, 1992, Jun-23, Volume: 43, Issue:12

    Topics: Aclarubicin; Base Composition; Cell Line; Cell Nucleus; Daunorubicin; DNA; Drug Resistance; Pyrans; Temperature; Thermodynamics

1992
Electrical alternans of the T-U wave without change in the QRS complex.
    Internal medicine (Tokyo, Japan), 1992, Volume: 31, Issue:4

    Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; Arrhythmias, Cardiac; Cytarabine; Daunorubicin; Electrocardiography; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged

1992
In vitro interaction of lithotripter shock waves and cytotoxic drugs.
    British journal of cancer, 1992, Volume: 66, Issue:1

    Topics: Aclarubicin; Animals; Antineoplastic Agents; Cell Survival; Cisplatin; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Leukemia L1210; Lithotripsy; Mice; Tumor Cells, Cultured

1992
[Studies on collagenase inhibitors. III. Inhibitory effects of anthracyclines on bacterial collagenase].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1991, Volume: 111, Issue:1

    Topics: Aclarubicin; Antibiotics, Antineoplastic; Bacteria; Daunorubicin; Doxorubicin; Microbial Collagenase

1991
Antagonistic effect of aclarubicin on daunorubicin-induced cytotoxicity in human small cell lung cancer cells: relationship to DNA integrity and topoisomerase II.
    Cancer research, 1991, Oct-01, Volume: 51, Issue:19

    Topics: Aclarubicin; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Ehrlich Tumor; Carcinoma, Small Cell; Colony-Forming Units Assay; Daunorubicin; DNA; DNA Damage; DNA Replication; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Drug Antagonism; Humans; In Vitro Techniques; Lung Neoplasms; Mice; Verapamil

1991
DNA-helix bending, stiffening and elongation on ligand binding; analysis for several DNA-drug systems, general viscometric DNA response and stereochemical implications.
    Journal of biomolecular structure & dynamics, 1991, Volume: 9, Issue:2

    Topics: Aclarubicin; Antibiotics, Antineoplastic; Dactinomycin; Daunorubicin; DNA; Intercalating Agents; Ligands; Mitomycin; Models, Molecular; Nucleic Acid Conformation; Viscosity

1991
Experimental transplantation models of mouse sarcoma 180 in ICR mice for evaluation of anti-tumor drugs.
    The Journal of veterinary medical science, 1991, Volume: 53, Issue:4

    Topics: Aclarubicin; Animals; Antineoplastic Agents; Daunorubicin; Disease Models, Animal; Doxorubicin; Lung Neoplasms; Male; Mice; Mice, Inbred ICR; Neoplasm Transplantation; Sarcoma 180; Skin Neoplasms; Specific Pathogen-Free Organisms

1991
Subrenal capsule assay of human tumor chemosensitivity.
    Neoplasma, 1991, Volume: 38, Issue:3

    Topics: Aclarubicin; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Colonic Neoplasms; Cyclophosphamide; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Evaluation Studies as Topic; Fluorouracil; Humans; Mice; Neoplasm Transplantation; Subrenal Capsule Assay

1991
[Torsade de pointes ventricular tachycardia in a patient with acute myelocytic leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1991, Volume: 32, Issue:9

    Topics: Aclarubicin; Adult; Antineoplastic Combined Chemotherapy Protocols; Daunorubicin; Electrocardiography; Female; Humans; Leukemia, Myeloid, Acute; Tachycardia

1991
Structure-activity relationship between anthracycline-induced differentiation and inhibition of glycoprotein synthesis in Friend erythroleukemia cells.
    Leukemia, 1991, Volume: 5, Issue:2

    Topics: Aclarubicin; Animals; Anthracyclines; Antibiotics, Antineoplastic; Cell Differentiation; Cell Line; Cell Survival; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Friend murine leukemia virus; Glycoproteins; Hemoglobins; Leukemia, Erythroblastic, Acute; Mannose; Mice; Tunicamycin

1991
Drug sensitivity test for acute myeloblastic leukemia by an efficient leukemic blast colony assay using 5637-conditioned medium as a stimulator.
    Journal of medicine, 1990, Volume: 21, Issue:6

    Topics: Aclarubicin; Adult; Aged; Aged, 80 and over; Culture Media; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Tumor Stem Cell Assay

1990
Comparison of the binding of anthracycline derivatives to purified DNA and to cell nuclei.
    Biochimica et biophysica acta, 1990, Nov-09, Volume: 1036, Issue:2

    Topics: Aclarubicin; Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Nucleus; Daunorubicin; DNA; Doxorubicin; Kinetics; Molecular Structure; Structure-Activity Relationship

1990
[The uptake of daunorubicin, adriamycin and aclarubicin into leukemic cells measured by flow cytometry].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:5

    Topics: Aclarubicin; Daunorubicin; Doxorubicin; Flow Cytometry; Humans; Leukemia, Lymphoid; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Tumor Cells, Cultured

1990
Effect of adriamycin on DNA, RNA and protein biosyntheses in mouse tissues, in connection with its cardiotoxicity.
    Japanese journal of cancer research : Gann, 1989, Volume: 80, Issue:10

    Topics: Aclarubicin; Animals; Carcinoma, Ehrlich Tumor; Daunorubicin; DNA; Doxorubicin; Glutathione Peroxidase; Heart Diseases; Kidney; Lipid Peroxidation; Liver; Lung; Male; Mice; Myocardium; Protein Biosynthesis; RNA

1989
In vitro evaluation of the potential of aclarubicin in the treatment of small cell carcinoma of the lung (SCCL).
    British journal of cancer, 1989, Volume: 60, Issue:6

    Topics: Aclarubicin; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood Proteins; Carcinoma, Small Cell; Daunorubicin; Doxorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Humans; In Vitro Techniques; Lung Neoplasms; Membrane Glycoproteins; Mitoxantrone; Tumor Stem Cell Assay

1989
[Chemotherapy of adult ANLL].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1989, Volume: 30, Issue:8

    Topics: Aclarubicin; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Daunorubicin; Drug Evaluation; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Mitoxantrone; Prednisolone; Remission Induction; Survival Rate; Vincristine

1989
[Relapse of gingival tumor during hematological remission in acute promyelocytic leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1989, Volume: 30, Issue:11

    Topics: Aclarubicin; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Gingival Neoplasms; Humans; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Middle Aged; Prednisolone; Recurrence; Remission Induction; Vinblastine; Vincristine

1989
Development of drug resistance in cultured clonogenic leukemic blast cells during the clinical course of myeloblastic leukemia.
    Oncology, 1989, Volume: 46, Issue:5

    Topics: Aclarubicin; Adult; Aged; Daunorubicin; Drug Resistance; Female; Humans; Leukemia, Myeloid, Acute; Male; Neoplastic Stem Cells; Tumor Cells, Cultured

1989
Potentiation of adriamycin accumulation and effectiveness in adriamycin-resistant cells by aclacinomycin A.
    Leukemia research, 1988, Volume: 12, Issue:5

    Topics: Aclarubicin; Animals; Antibiotics, Antineoplastic; Breast Neoplasms; Daunorubicin; Doxorubicin; Drug Resistance; Drug Synergism; Epithelial Cells; Humans; Kidney; Leukemia, Experimental; Naphthacenes; Tumor Cells, Cultured

1988
Evidence of multifactorial mechanisms in an adriamycin-resistant HL-60 promyelocytic leukemia cell line.
    Cancer biochemistry biophysics, 1988, Volume: 10, Issue:1

    Topics: Aclarubicin; Antibiotics, Antineoplastic; Biological Transport; Cell Differentiation; Cell Division; Cell Line; Daunorubicin; DNA, Neoplasm; Doxorubicin; Humans; Kinetics; Leukemia, Promyelocytic, Acute

1988
Inhibition of alpha-tocopherol and calcium calmodulin-stimulated phosphodiesterase activity in vitro by anthracyclines.
    Clinical and experimental pharmacology & physiology, 1988, Volume: 15, Issue:11

    Topics: Aclarubicin; Animals; Antibiotics, Antineoplastic; Brain; Calmodulin; Cattle; Daunorubicin; Doxorubicin; Male; Phosphodiesterase Inhibitors; Rats; Rats, Inbred Strains; Vitamin E

1988
Treatment of acute non-lymphocytic leukemia with alternating non-cross resistant chemotherapy.
    Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society, 1988, Volume: 51, Issue:8

    Topics: Aclarubicin; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Resistance; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisolone; Prognosis; Remission Induction; Vincristine

1988
Anthracycline antibiotics. Interaction with DNA and nucleosomes and inhibition of DNA synthesis.
    Biochemistry, 1987, Apr-07, Volume: 26, Issue:7

    Topics: Aclarubicin; Aminoglycosides; Anthracyclines; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Daunorubicin; DNA; DNA Polymerase I; DNA Replication; Escherichia coli; Kinetics; Naphthacenes; Nucleosomes

1987
[Mucosal injury of aclacinomycin A in patients with adult acute leukemia--comparison of BH-AC. AMP therapy and BH-AC. DMP therapy].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1986, Volume: 27, Issue:4

    Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Hemorrhage; Humans; Leukemia; Male; Mercaptopurine; Middle Aged; Mucous Membrane; Naphthacenes; Prednisolone; Urinary Bladder Diseases

1986
Anthracycline induced myocardial damage. An analysis of 16 autopsy cases.
    Pathology, research and practice, 1986, Volume: 181, Issue:4

    Topics: Aclarubicin; Adult; Aged; Antibiotics, Antineoplastic; Cardiomyopathies; Daunorubicin; Doxorubicin; Female; Humans; Male; Middle Aged; Myocardium; Naphthacenes

1986
[Phase II trial of mitoxantrone in patients with relapsed and refractory acute leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:10

    Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Aged; Blast Crisis; Child; Daunorubicin; Drug Evaluation; Drug Resistance; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Naphthacenes

1986
Effects on leukemic clonogenic cells in murine myeloid leukemia of 1-beta-D-arabinofuranosylcytosine and the anthracyclines adriamycin, daunomycin, aclacinomycin A, and 4'-epidoxorubicin.
    Cancer research, 1987, May-01, Volume: 47, Issue:9

    Topics: Aclarubicin; Animals; Antibiotics, Antineoplastic; Clone Cells; Colony-Forming Units Assay; Cytarabine; Daunorubicin; Doxorubicin; Epirubicin; Kinetics; Leukemia, Myeloid, Acute; Mice; Naphthacenes

1987
Daunorubicin versus aclarubicin in combination with cytarabine and thioguanine in elderly patients with acute nonlymphocytic leukemia, a preliminary report.
    European journal of haematology. Supplementum, 1987, Volume: 47

    Topics: Aclarubicin; Acute Disease; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Male; Middle Aged; Naphthacenes; Thioguanine

1987
Interaction of aclarubicin with DNA as compared with daunorubicin and doxorubicin.
    Nihon Gan Chiryo Gakkai shi, 1986, Dec-20, Volume: 21, Issue:10

    Topics: Aclarubicin; Animals; Antibiotics, Antineoplastic; Binding Sites; Cattle; Cells, Cultured; Daunorubicin; DNA; Doxorubicin; Drug Interactions; Female; Leukemia L1210; Mice; Naphthacenes

1986
Induction of chromosomal aberrations by the anthracycline antitumor antibiotics N,N-dimethyldaunomycin and aclacinomycin A.
    Experientia, 1987, May-15, Volume: 43, Issue:5

    Topics: Aclarubicin; Animals; Antibiotics, Antineoplastic; Cell Line; Chromosome Aberrations; Daunorubicin; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Mice; Mutation; Naphthacenes

1987
Age adapted induction and intensified consolidation therapy in acute myelogenous leukemia.
    Onkologie, 1986, Volume: 9, Issue:3

    Topics: Aclarubicin; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Naphthacenes; Prognosis

1986
Aclacinomycin-A in the induction treatment of childhood AML.
    Onkologie, 1986, Volume: 9, Issue:3

    Topics: Aclarubicin; Adolescent; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Etoposide; Female; Follow-Up Studies; Humans; Infant; Infusions, Parenteral; Leukemia, Myeloid, Acute; Male; Naphthacenes; Thioguanine

1986
A phase II study of mitoxantrone in acute leukemia.
    Investigational new drugs, 1985, Volume: 3, Issue:2

    Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Alanine Transaminase; Anthraquinones; Antineoplastic Agents; Child; Daunorubicin; Doxorubicin; Drug Evaluation; Drug Resistance; Electrocardiography; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukocyte Count; Male; Middle Aged; Mitoxantrone; Naphthacenes

1985
In vitro sensitivity of leukemic clonogenic cells to four anthracyclines (adriamycin, daunorubicin, rubidazone and aclacinomycin) in human acute myeloid leukemia.
    Nouvelle revue francaise d'hematologie, 1985, Volume: 27, Issue:3

    Topics: Aclarubicin; Aged; Bone Marrow; Cells, Cultured; Child; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Humans; Leukemia, Myeloid, Acute; Middle Aged; Naphthacenes

1985
Anthracycline antibiotic reduction by spinach ferredoxin-NADP+ reductase and ferredoxin.
    Biochemistry, 1985, Jul-02, Volume: 24, Issue:14

    Topics: Aclarubicin; Anti-Bacterial Agents; Daunorubicin; Ferredoxin-NADP Reductase; Ferredoxins; Manganese; NADH, NADPH Oxidoreductases; Naphthacenes; Nogalamycin; Plants; Stereoisomerism; Structure-Activity Relationship

1985
[Gastrointestinal symptoms of aclacinomycin A in patients with adult acute nonlymphocytic leukemia--comparison of BH-AC-DMP therapy and BH-AC-AMP therapy].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1985, Volume: 26, Issue:4

    Topics: Aclarubicin; Acute Disease; Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Digestive System; Female; Gastrointestinal Diseases; Humans; Leukemia; Male; Mercaptopurine; Naphthacenes; Prednisolone

1985
Interaction of anthracyclines with covalently closed circular DNA.
    Molecular pharmacology, 1980, Volume: 17, Issue:1

    Topics: Aclarubicin; Anthracyclines; Antibiotics, Antineoplastic; Bleomycin; Carubicin; Centrifugation, Density Gradient; Daunorubicin; Diffusion; DNA, Circular; Doxorubicin; Drug Interactions; Electrophoresis, Agar Gel; Molecular Conformation; Naphthacenes

1980
Recent studies on antibiotics and small molecular immunomodulators with potential usefulness in treating lung cancer: Part I - Antitumor antibiotics and their derivatives.
    International journal of clinical pharmacology, therapy, and toxicology, 1982, Volume: 20, Issue:1

    Topics: Aclarubicin; Adjuvants, Immunologic; Animals; Antibiotics, Antineoplastic; Bleomycin; Daunorubicin; Doxorubicin; Humans; Leukemia L1210; Lung; Lung Neoplasms; Mice; Molecular Weight; Naphthacenes; Peplomycin; Structure-Activity Relationship

1982
Anthracycline-induced histamine release from rat mast cells.
    Agents and actions, 1982, Volume: 12, Issue:4

    Topics: Aclarubicin; Animals; Antibiotics, Antineoplastic; Daunorubicin; Doxorubicin; Histamine Release; Male; Mast Cells; Naphthacenes; Rats; Rats, Inbred Strains; Staining and Labeling

1982
[Comparative evaluation of combined chemotherapeutic regimens in acute non-lymphocytic leukemia].
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1983, Volume: 58, Issue:3

    Topics: Aclarubicin; Acute Disease; Adult; Age Factors; Ancitabine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Mercaptopurine; Middle Aged; Naphthacenes; Prednisolone

1983
[Studies on the mechanism of drug resistance in tumor cells and a new antitumor antibiotic].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:12 Pt 2

    Topics: Aclarubicin; Animals; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Bleomycin; Cell Cycle; Cell Line; Cells, Cultured; Cricetinae; Cricetulus; Daunorubicin; Doxorubicin; Drug Resistance; Lymphoma; Mice; Naphthacenes; Neoplasms, Experimental

1984
Mutagenicity of eight anthracycline derivatives in five strains of Salmonella typhimurium.
    European journal of cancer & clinical oncology, 1983, Volume: 19, Issue:5

    Topics: Aclarubicin; Antibiotics, Antineoplastic; Daunorubicin; Doxorubicin; Epirubicin; Mutagenicity Tests; Mutagens; Naphthacenes; Salmonella typhimurium

1983
Direct enzyme-catalyzed reduction of anthracyclines by reduced nicotinamide adenine dinucleotide.
    Biochemistry, 1983, Mar-15, Volume: 22, Issue:6

    Topics: Aclarubicin; Antibiotics, Antineoplastic; Daunorubicin; FMN Reductase; Hydroquinones; Kinetics; NAD; NADH, NADPH Oxidoreductases; Naphthacenes; Oxidation-Reduction; Vibrio

1983
Sensitivity of bone marrow hematopoietic colony-forming cells from mice, dogs, and humans to carminomycin, marcellomycin, aclacinomycin A, and N,N-dibenzyldaunorubicin and its relationship to clinical toxicity.
    Cancer research, 1983, Volume: 43, Issue:6

    Topics: Aclarubicin; Animals; Anthracyclines; Antibiotics, Antineoplastic; Carubicin; Daunorubicin; Dogs; Dose-Response Relationship, Drug; Female; Hematopoietic Stem Cells; Male; Mice; Naphthacenes; Species Specificity

1983
Anthracycline-binding induced DNA stiffening, bending and elongation; stereochemical implications from viscometric investigations.
    Nucleic acids research, 1983, May-25, Volume: 11, Issue:10

    Topics: Aclarubicin; Animals; Cattle; Daunorubicin; DNA; Doxorubicin; Kinetics; Mathematics; Models, Molecular; Mutagens; Naphthacenes; Nucleic Acid Conformation; Structure-Activity Relationship; Thymus Gland

1983
[Adriamycin-aclacinomycin therapy (AA therapy) for acute leukemia unresponsive to BH-AC-DMP therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:6

    Topics: Aclarubicin; Adolescent; Adult; Aged; Cytarabine; Daunorubicin; Doxorubicin; Drug Resistance; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Naphthacenes; Prednisolone

1983
[Prediction of resistance to remission induction in acute leukemia in adult].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:7

    Topics: Aclarubicin; Adult; Antineoplastic Agents; Bone Marrow Examination; Daunorubicin; Drug Resistance; Drug Therapy, Combination; Humans; Leukemia; Naphthacenes; Retrospective Studies

1983
Determination of aclacinomycin A by reversed-phase high-performance liquid chromatography.
    Journal of chromatography, 1983, Oct-14, Volume: 277

    Topics: Aclarubicin; Chromatography, High Pressure Liquid; Daunorubicin; Humans; Naphthacenes

1983
Acute anthracycline cardiotoxicity. Comparative morphologic study of three analogues.
    Cancer, 1984, Apr-15, Volume: 53, Issue:8

    Topics: Aclarubicin; Animals; Antibiotics, Antineoplastic; Cell Nucleus; Chemotherapy, Cancer, Regional Perfusion; Cytoplasm; Daunorubicin; Heart; Heart Diseases; Myocardium; Naphthacenes; Rabbits; Time Factors

1984
Continuous extraction of urinary anthracycline antitumor antibiotics with the horizontal flow-through coil planet centrifuge.
    Journal of chromatography, 1984, May-11, Volume: 307, Issue:2

    Topics: 1-Butanol; Aclarubicin; Antibiotics, Antineoplastic; Butanols; Centrifugation; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Daunorubicin; Doxorubicin; Humans; Naphthacenes

1984
[New anthracycline antibiotics and derivatives].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:12 Pt 2

    Topics: Aclarubicin; Animals; Anthracyclines; Antibiotics, Antineoplastic; Daunorubicin; Doxorubicin; Leukemia L1210; Mice; Naphthacenes; Structure-Activity Relationship

1984
Aclarubicin in the treatment of acute nonlymphocytic leukemia refractory to treatment with daunorubicin and cytarabine: a phase II trial.
    Cancer treatment reports, 1984, Volume: 68, Issue:10

    Topics: Aclarubicin; Acute Disease; Adult; Aged; Antibiotics, Antineoplastic; Cytarabine; Daunorubicin; Drug Evaluation; Heart; Humans; Leukemia; Leukopenia; Middle Aged; Naphthacenes; Prospective Studies; Thrombocytopenia

1984
Comparative flavoprotein catalysis of anthracycline antibiotic. Reductive cleavage and oxygen consumption.
    Molecular pharmacology, 1981, Volume: 19, Issue:1

    Topics: Aclarubicin; Animals; Antibiotics, Antineoplastic; Daunorubicin; Doxorubicin; Flavoproteins; In Vitro Techniques; Male; NAD; Naphthacenes; Oxidation-Reduction; Oxygen Consumption; Rats; Xanthine Oxidase

1981
Comparative nuclear and cellular incorporation of daunorubicin, doxorubicin, carminomycin, marcellomycin, aclacinomycin A and AD 32 in daunorubicin-sensitive and -resistant Ehrlich ascites in vitro.
    Journal of cancer research and clinical oncology, 1980, Volume: 98, Issue:2

    Topics: Aclarubicin; Animals; Anthracyclines; Antibiotics, Antineoplastic; Carcinoma, Ehrlich Tumor; Carubicin; Cell Nucleus; Daunorubicin; DNA, Neoplasm; Doxorubicin; Drug Resistance; Female; In Vitro Techniques; Mice; Naphthacenes

1980
New anthracycline antibiotic aclacinomycin A: experimental studies and correlations with clinical trials.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1981, Volume: 76

    Topics: Aclarubicin; Animals; Antibiotics, Antineoplastic; Cricetinae; Daunorubicin; Dogs; Doxorubicin; Drug Evaluation; Drug Evaluation, Preclinical; Female; Humans; In Vitro Techniques; Male; Mice; Naphthacenes; Neoplasms; Neoplasms, Experimental; Rabbits; Rats

1981
Stability of anthracycline antitumor agents in four infusion fluids.
    American journal of hospital pharmacy, 1981, Volume: 38, Issue:4

    Topics: Aclarubicin; Antibiotics, Antineoplastic; Chromatography, High Pressure Liquid; Daunorubicin; Doxorubicin; Drug Stability; Hydrogen-Ion Concentration; Infusions, Parenteral; Naphthacenes; Pharmacopoeias as Topic; United States

1981
[Remission induction by ACM-A and BH-AC on acute promyelocytic leukemia which is resistant to DNR and CA (author's transl)].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1981, Volume: 22, Issue:7

    Topics: Aclarubicin; Adult; Cytarabine; Daunorubicin; Drug Resistance; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Male; Naphthacenes

1981
Future clinical investigations with anthracycline antibiotics in relation to daunorubicin.
    Cancer treatment reports, 1981, Volume: 65 Suppl 4

    Topics: Aclarubicin; Antibiotics, Antineoplastic; Carubicin; Child; Daunorubicin; Doxorubicin; Drug Evaluation; Humans; Leukemia; Naphthacenes; Structure-Activity Relationship

1981
Cellular pharmacokinetics of aclacinomycin A in cultured L1210 cells. Comparison with daunorubicin and doxorubicin.
    Cancer chemotherapy and pharmacology, 1982, Volume: 8, Issue:2

    Topics: Aclarubicin; Animals; Antibiotics, Antineoplastic; Cells, Cultured; Chromatography, High Pressure Liquid; Daunorubicin; DNA, Neoplasm; Doxorubicin; Kinetics; Leukemia L1210; Mice; Mice, Inbred DBA; Naphthacenes; Subcellular Fractions

1982
[Changes in the spatial organization of DNA molecules induced by anthracycline antibiotics].
    Antibiotiki, 1982, Volume: 27, Issue:12

    Topics: Aclarubicin; Aminoglycosides; Animals; Anthracyclines; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Carubicin; Cattle; Chemical Phenomena; Chemistry; Daunorubicin; DNA; Doxorubicin; Fishes; Male; Molecular Conformation; Naphthacenes; Nucleic Acid Conformation; Spermatozoa

1982
[Cardiotoxicity of daunorubicin and aclacinomycin A in patients with acute leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1982, Volume: 9, Issue:3

    Topics: Aclarubicin; Acute Disease; Adult; Antibiotics, Antineoplastic; Daunorubicin; Electrocardiography; Female; Heart; Humans; Leukemia; Male; Naphthacenes; Systole

1982
[Comparative evaluation of a combination of daunorubicin and cytosine arabinoside and that of aclarubicin and cytosine arabinoside in remission induction in acute non-lymphocytic leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1982, Volume: 9, Issue:9

    Topics: Aclarubicin; Adult; Aged; Antibiotics, Antineoplastic; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Naphthacenes; Random Allocation

1982
[Successful adjuvant therapy of M-CSF with chemotherapy of two cases of chemotherapy resistant acute promyelocytic leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1995, Volume: 36, Issue:6

    Topics: Aclarubicin; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Resistance; Female; Humans; Leukemia, Promyelocytic, Acute; Macrophage Colony-Stimulating Factor; Male; Mercaptopurine; Prednisolone; Remission Induction

1995
Synergistic and antagonistic effects of myeloid growth factors on in vitro cellular killing by cytotoxic drugs.
    Leukemia research, 1993, Volume: 17, Issue:8

    Topics: Aclarubicin; Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Death; Cell Survival; Coloring Agents; Cytarabine; Daunorubicin; Drug Antagonism; Drug Screening Assays, Antitumor; Drug Synergism; Female; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Leukemia, Myeloid; Male; Middle Aged; Prospective Studies; Remission Induction

1993
In vitro anthracycline cross-resistance pattern in childhood acute lymphoblastic leukaemia.
    British journal of cancer, 1995, Volume: 71, Issue:6

    Topics: Aclarubicin; Antibiotics, Antineoplastic; Bone Marrow; Child; Daunorubicin; Dose-Response Relationship, Drug; Drug Resistance; Humans; Idarubicin; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence

1995
Cross resistance relevance of the chemical structure of different anthracyclines in multidrug resistant cells.
    Pathologie-biologie, 1994, Volume: 42, Issue:4

    Topics: Aclarubicin; Animals; Carubicin; Cells, Cultured; Daunorubicin; DNA, Neoplasm; Doxorubicin; Drug Resistance; Humans; In Vitro Techniques; Mice; Tumor Cells, Cultured; Verapamil

1994
The efflux of anthracyclines in multidrug-resistant cell lines.
    Biochemical pharmacology, 1993, Oct-19, Volume: 46, Issue:8

    Topics: Aclarubicin; Animals; Anthracyclines; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Cyclosporine; Daunorubicin; Doxorubicin; Drug Resistance; Humans; Membrane Glycoproteins; Mice; Phenotype; Tumor Cells, Cultured; Verapamil

1993
Inhibitory effects of daunorubicin on endothelium-dependent vasorelaxing response to acetylcholine of rat aorta.
    The Journal of pharmacy and pharmacology, 1994, Volume: 46, Issue:4

    Topics: Acetylcholine; Aclarubicin; Animals; Aorta; Cyclic GMP; Daunorubicin; Drug Interactions; Endothelium, Vascular; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Potassium Channel Blockers; Rats; Rats, Wistar; Tetraethylammonium; Tetraethylammonium Compounds

1994
[The comparative evaluation of the efficacy of different therapeutic plans in acute nonlymphocytic leukemias].
    Terapevticheskii arkhiv, 1993, Volume: 65, Issue:7

    Topics: Aclarubicin; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Doxorubicin; Drug Evaluation; Hematopoiesis; Humans; Idarubicin; Leukemia, Myeloid, Acute; Mitoxantrone; Prednisolone; Remission Induction; Time Factors; Vincristine

1993
[The current chemotherapy of acute myeloid leukemias in adults].
    Terapevticheskii arkhiv, 1993, Volume: 65, Issue:7

    Topics: Aclarubicin; Acute Disease; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Humans; Idarubicin; Leukemia, Myeloid; Mitoxantrone; Prognosis; Remission Induction; Time Factors

1993
[Intracellular measurement of anthracyclines with flow cytometry].
    Padiatrie und Padologie, 1993, Volume: 28, Issue:6

    Topics: Aclarubicin; Antibiotics, Antineoplastic; Cells, Cultured; Daunorubicin; Doxorubicin; Epirubicin; Flow Cytometry; Humans; Leukocytes; Mitoxantrone

1993
[Short-term intensive consolidation chemotherapy in the treatment of acute nonlymphocytic leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:2

    Topics: Aclarubicin; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Prognosis; Survival Rate; Vinblastine; Vincristine

1994
[Six cases of therapy related leukemia; case reports and review of the literature].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:10

    Topics: Aclarubicin; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Daunorubicin; Female; Humans; Leukemia, Myelomonocytic, Acute; Leukemia, Promyelocytic, Acute; Lung Neoplasms; Lymphoma; Male; Middle Aged; Neoplasms, Second Primary; Survival Rate

1993
Double mutations of the N-ras gene in a patient with acute myelomonocytic leukemia.
    International journal of hematology, 1995, Volume: 61, Issue:4

    Topics: Aclarubicin; Alleles; Antineoplastic Combined Chemotherapy Protocols; Chromosome Deletion; Chromosomes, Human, Pair 12; Chromosomes, Human, Pair 9; Codon; Cytarabine; Daunorubicin; Disease Progression; Doxorubicin; Etoposide; Fatal Outcome; Genes, ras; Genetic Vectors; Humans; Karyotyping; Leukemia, Myelomonocytic, Acute; Male; Mercaptopurine; Middle Aged; Mitoxantrone; Point Mutation; Prednisolone; Vinblastine; Vincristine

1995
Pneumocystis carinii pneumonia in adults with acute leukaemia: is there a need for primary chemoprophylaxis?
    European journal of haematology, 1996, Volume: 56, Issue:3

    Topics: Aclarubicin; Acute Disease; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cohort Studies; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Etoposide; Female; Finland; Humans; Immunocompromised Host; Incidence; Leukemia; Male; Mercaptopurine; Methotrexate; Middle Aged; Mitoxantrone; Pneumonia, Pneumocystis; Prednisone; Premedication; Retrospective Studies; Thioguanine; Trimethoprim, Sulfamethoxazole Drug Combination; Vincristine

1996
Quantitation of the nucleophosmin/B23-translocation using imaging analysis.
    Cancer letters, 1996, Feb-27, Volume: 100, Issue:1-2

    Topics: Aclarubicin; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Nucleolus; Dactinomycin; Daunorubicin; Dose-Response Relationship, Drug; Fluorescent Antibody Technique; Humans; Image Processing, Computer-Assisted; Leukemia, Monocytic, Acute; Nuclear Proteins; Nucleophosmin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured

1996
Enzymatic and chemical footprinting of anthracycline antitumor antibiotics and related saccharide side chains.
    Biochemistry, 1996, Jun-18, Volume: 35, Issue:24

    Topics: Aclarubicin; Anthracyclines; Antibiotics, Antineoplastic; Base Sequence; Binding Sites; Carbohydrate Conformation; Carbohydrate Sequence; Daunorubicin; Deoxyribonuclease BamHI; Deoxyribonuclease EcoRI; Deoxyribonuclease I; DNA; DNA Footprinting; Molecular Sequence Data; Oligosaccharides; Plasmids

1996
[Long-term selective beta 1-blockade therapy for a patient with anthracycline-induced cardiomyopathy].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1995, Volume: 36, Issue:11

    Topics: Aclarubicin; Adrenergic beta-Antagonists; Adult; Antibiotics, Antineoplastic; Cardiomyopathy, Hypertrophic; Chronic Disease; Daunorubicin; Drug Administration Schedule; Female; Heart Failure; Humans; Leukemia, Myelomonocytic, Acute; Metoprolol; Mitoxantrone

1995
Relation of blast cell survival and proliferation to chemotherapy resistance in AML.
    British journal of haematology, 1996, Volume: 93, Issue:4

    Topics: Aclarubicin; Adolescent; Adult; Aged; Antineoplastic Agents; Cell Differentiation; Cell Survival; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Female; Humans; Infant; Infant, Newborn; Leukemia, Myeloid; Leukocyte Count; Male; Middle Aged; Mitoxantrone; Treatment Outcome; Tumor Cells, Cultured

1996
[Genotoxic and mutagenic activity of antineoplastic anthracyclines and their aglycones: study in two test-systems].
    Genetika, 1996, Volume: 32, Issue:2

    Topics: Aclarubicin; Antibiotics, Antineoplastic; Carubicin; Daunorubicin; Doxorubicin; Intercalating Agents; Mutagenicity Tests; Mutagens; Naphthacenes; Nucleic Acid Conformation; Salmonella typhimurium; SOS Response, Genetics; Structure-Activity Relationship

1996
Human hepatoma cells rich in P-glycoprotein are sensitive to aclarubicin and resistant to three other anthracyclines.
    British journal of cancer, 1996, Volume: 74, Issue:11

    Topics: Aclarubicin; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Hepatocellular; Cell Division; Cell Membrane; Daunorubicin; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Epirubicin; Humans; Liver Neoplasms; Microscopy, Confocal; Tumor Cells, Cultured

1996
[Echocardiographic evaluation of cardiotoxicity induced by anthracycline therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:5

    Topics: Aclarubicin; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Breast Neoplasms; Daunorubicin; Doxorubicin; Echocardiography; Epirubicin; Female; Heart; Hematologic Diseases; Humans; Male; Middle Aged; Mitoxantrone; Radionuclide Imaging; Stroke Volume

1997
Minimal Streptomyces sp. strain C5 daunorubicin polyketide biosynthesis genes required for aklanonic acid biosynthesis.
    Journal of bacteriology, 1997, Volume: 179, Issue:8

    Topics: Aclarubicin; Acyltransferases; Anthraquinones; Chromosomes, Bacterial; Daunorubicin; Genes, Bacterial; Models, Chemical; Mutation; Open Reading Frames; Restriction Mapping; Species Specificity; Streptomyces

1997
In vitro drug sensitivity testing can predict induction failure and early relapse of childhood acute lymphoblastic leukemia.
    Blood, 1997, Apr-15, Volume: 89, Issue:8

    Topics: Aclarubicin; Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bleomycin; Bone Marrow; Cell Survival; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Disease-Free Survival; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Etoposide; Follow-Up Studies; Humans; Infant; Infant, Newborn; Life Tables; Melphalan; Methotrexate; Mitomycin; Mitoxantrone; Neoplastic Stem Cells; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Recurrence; Remission Induction; Tumor Cells, Cultured; Vincristine

1997
Characterization of Streptomyces nogalater genes encoding enzymes involved in glycosylation steps in nogalamycin biosynthesis.
    Molecular & general genetics : MGG, 1997, Volume: 256, Issue:2

    Topics: Aclarubicin; Amino Acid Sequence; Cloning, Molecular; Daunorubicin; DNA, Bacterial; Genes, Bacterial; Genetic Complementation Test; Molecular Sequence Data; Nogalamycin; Open Reading Frames; Plasmids; Racemases and Epimerases; Restriction Mapping; Rhamnose; Sequence Alignment; Sequence Analysis, DNA; Streptomyces; UDPglucose 4-Epimerase

1997
Degree of DNA unwinding caused by the binding of aclacinomycin A.
    Chemical & pharmaceutical bulletin, 1997, Volume: 45, Issue:10

    Topics: Aclarubicin; Antibiotics, Antineoplastic; Binding Sites; Daunorubicin; DNA Damage; DNA Topoisomerases, Type I; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Ethidium; Models, Theoretical; Plasmids

1997
MDR1 gene expression and drug resistance of AML cells.
    British journal of haematology, 1998, Volume: 100, Issue:3

    Topics: Aclarubicin; Acute Disease; Antineoplastic Agents; Cytarabine; Daunorubicin; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Gene Expression; Genes, MDR; Humans; Lethal Dose 50; Leukemia, Myeloid; Mitoxantrone; Tumor Cells, Cultured

1998
Differential resistance to anthracyclines in P-glycoprotein-expressing human hepatoma cells.
    International journal of clinical pharmacology and therapeutics, 1998, Volume: 36, Issue:2

    Topics: Aclarubicin; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Hepatocellular; Cyclosporins; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Epirubicin; Humans; Liver Neoplasms; Tumor Cells, Cultured

1998
[Retrospective analysis of elderly patients > or = 60 years of age with acute leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1998, Volume: 39, Issue:3

    Topics: Aclarubicin; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Daunorubicin; DNA; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Retrospective Studies; Vincristine

1998
Leukaemia cell drug resistance and prognostic factors in AML.
    European journal of haematology, 1999, Volume: 63, Issue:4

    Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Blast Crisis; Child; Child, Preschool; Cytarabine; Cytogenetic Analysis; Daunorubicin; Drug Resistance, Neoplasm; Female; Humans; Infant; Leukemia, Myeloid; Male; Middle Aged; Multivariate Analysis; Prognosis; Tetrazolium Salts

1999
Molecular effects of topoisomerase II inhibitors in AML cell lines: correlation of apoptosis with topoisomerase II activity but not with DNA damage.
    Leukemia, 1999, Volume: 13, Issue:11

    Topics: Aclarubicin; Acute Disease; Antineoplastic Agents; Apoptosis; Cell Nucleus; Comet Assay; Daunorubicin; DNA; DNA Damage; DNA Topoisomerases, Type II; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Etoposide; fas Receptor; Genes, p53; Humans; Intercalating Agents; Leukemia, Myeloid; Mitochondria; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1999
Pretreatment leukaemia cell drug resistance is correlated to clinical outcome in acute myeloid leukaemia.
    European journal of haematology, 2001, Volume: 66, Issue:3

    Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neoplastic Stem Cells; Prognosis; Remission Induction; Survival Analysis; Thioguanine; Treatment Outcome; Tumor Cells, Cultured

2001
FAB M4 and high CD14 surface expression is associated with high cellular resistance to Ara-C and daunorubicin: implications for clinical outcome in acute myeloid leukaemia.
    European journal of haematology, 2001, Volume: 67, Issue:4

    Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Amsacrine; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cohort Studies; Cytarabine; Daunorubicin; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid; Leukemia, Myelomonocytic, Acute; Lipopolysaccharide Receptors; Male; Middle Aged; Mitoxantrone; Multivariate Analysis; Neoplastic Stem Cells; Thioguanine; Treatment Outcome

2001
Comparison of anthracycline-induced death of human leukemia cells: programmed cell death versus necrosis.
    Apoptosis : an international journal on programmed cell death, 2002, Volume: 7, Issue:6

    Topics: Aclarubicin; Antibiotics, Antineoplastic; Apoptosis; Apoptosis Regulatory Proteins; Caspases; Cell Death; Cell Membrane; Daunorubicin; DNA Fragmentation; Doxorubicin; Enzyme Activation; HL-60 Cells; Humans; Jurkat Cells; Leukemia; Models, Biological; Necrosis; Phosphatidylserines; Proteins

2002
Morphological and biochemical changes in human fibroblast lines induced by anthracyclines during apoptosis.
    Cellular & molecular biology letters, 2003, Volume: 8, Issue:1

    Topics: Aclarubicin; Anthracyclines; Apoptosis; Calcium; Caspase 3; Caspases; Cell Line; Daunorubicin; Enzyme Activation; Fibroblasts; Humans; Idarubicin; Intracellular Fluid; Trisomy

2003
Activity of topoisomerase inhibitors daunorubicin, idarubicin, and aclarubicin in the Drosophila Somatic Mutation and Recombination Test.
    Environmental and molecular mutagenesis, 2004, Volume: 43, Issue:4

    Topics: Aclarubicin; Animals; Biological Assay; Daunorubicin; DNA Mutational Analysis; Dose-Response Relationship, Drug; Drosophila; Idarubicin; Mutagenesis; Topoisomerase Inhibitors; Wings, Animal

2004
Thiol oxidation induced by oxidative action of adriamycin.
    Free radical research, 2004, Volume: 38, Issue:9

    Topics: Aclarubicin; Antibiotics, Antineoplastic; Benzoquinones; Creatine Kinase; Daunorubicin; Doxorubicin; Electron Spin Resonance Spectroscopy; Epirubicin; Free Radicals; Glutathione; Horseradish Peroxidase; Hydrogen Peroxide; Hypoxanthine; Idarubicin; Oxidation-Reduction; Sulfhydryl Compounds; Xanthine Oxidase

2004
Engineered biosynthesis of aklanonic acid analogues.
    Journal of the American Chemical Society, 2005, Sep-07, Volume: 127, Issue:35

    Topics: Aclarubicin; Actinomycetales; Anthracyclines; Anthraquinones; Antibiotics, Antineoplastic; Base Sequence; Binding Sites; Biotechnology; Daunorubicin; Doxorubicin; Esters; Macrolides; Molecular Sequence Data; Polyketide Synthases

2005
[Transfection of HL-60 cells with CYP3A5 gene induces drug-resistant phenotype].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2005, Volume: 27, Issue:8

    Topics: Aclarubicin; Antibiotics, Antineoplastic; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; HL-60 Cells; Humans; Phenotype; Plasmids; Recombination, Genetic; Transfection; Vincristine

2005
Chemical profiling of the genome with anti-cancer drugs defines target specificities.
    Nature chemical biology, 2015, Volume: 11, Issue:7

    Topics: Aclarubicin; Antineoplastic Agents; Cell Line, Tumor; Chromatin; Daunorubicin; DNA Damage; DNA, Neoplasm; Etoposide; Gene Expression Regulation, Neoplastic; Genome, Human; Histones; Humans; Molecular Targeted Therapy; Neoplasms; Organ Specificity; Protein Transport; Structure-Activity Relationship; Topoisomerase Inhibitors; Topotecan

2015
Increasing aclarubicin dose in low-dose cytarabine and aclarubicin in combination with granulocyte colony-stimulating factor (CAG regimen) is efficacious as salvage chemotherapy for relapsed/refractory mixed-phenotype acute leukemia.
    Leukemia research, 2015, Volume: 39, Issue:8

    Topics: Aclarubicin; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Recurrence; Retrospective Studies; Salvage Therapy; Treatment Outcome; Vincristine; Young Adult

2015
A low-dose cytarabine, aclarubicin and granulocyte colony-stimulating factor priming regimen versus a daunorubicin plus cytarabine regimen as induction therapy for older patients with acute myeloid leukemia: A propensity score analysis.
    Leukemia research, 2016, Volume: 42

    Topics: Aclarubicin; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Granulocyte Colony-Stimulating Factor; Humans; Induction Chemotherapy; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Propensity Score; Proportional Hazards Models; Retrospective Studies

2016
The outcome and prognostic factors of 248 elderly patients with acute myeloid leukemia treated with standard-dose or low-intensity induction therapy.
    Medicine, 2016, Volume: 95, Issue:30

    Topics: Aclarubicin; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Induction Chemotherapy; L-Lactate Dehydrogenase; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Prognosis; Retrospective Studies

2016
Efficacy of common salvage chemotherapy regimens in patients with refractory or relapsed acute myeloid leukemia: A retrospective cohort study.
    Medicine, 2018, Volume: 97, Issue:39

    Topics: Aclarubicin; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cohort Studies; Cytarabine; Daunorubicin; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Harringtonines; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Retrospective Studies; Salvage Therapy; Survival Rate; Treatment Outcome; Vidarabine; Young Adult

2018