dau 6285 has been researched along with tropisetron in 6 studies
| Studies (dau 6285) | Trials (dau 6285) | Recent Studies (post-2010) (dau 6285) | Studies (tropisetron) | Trials (tropisetron) | Recent Studies (post-2010) (tropisetron) |
|---|---|---|---|---|---|
| 21 | 0 | 0 | 944 | 218 | 150 |
| Protein | Taxonomy | dau 6285 (IC50) | tropisetron (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 3.1623 | |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 3.1623 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 3.45 | |
| Neuronal acetylcholine receptor subunit beta-4 | Homo sapiens (human) | 1.8 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.488 | |
| Neuronal acetylcholine receptor subunit alpha-3 | Homo sapiens (human) | 1.8 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bockaert, J; Claeysen, S; Dumuis, A; Journot, L; Sebben, M | 1 |
| Candura, SM; Coccini, T; Manzo, L; Onori, L; Rizzi, CA; Tonini, M | 2 |
| Ansanay, H; Dumuis, A; Giraldo, E; Gozlan, H; Ladinsky, H; Monferini, E; Rizzi, CA; Schiantarelli, P; Sebben, M; Turconi, M | 1 |
| Giraldo, E; Giudici, L; Sagrada, A; Schiavone, A; Turconi, M | 1 |
| Contesse, V; Delarue, C; Hamel, C; Lefebvre, H; Vaudry, H | 1 |
6 other study(ies) available for dau 6285 and tropisetron
| Article | Year |
|---|---|
Cloning, expression and pharmacology of the mouse 5-HT(4L) receptor.
Topics: Age Factors; Amino Acid Sequence; Animals; Animals, Newborn; Base Sequence; Binding Sites; Brain; Brain Chemistry; Cloning, Molecular; Inferior Colliculi; Mice; Molecular Sequence Data; Rats; Rats, Inbred Strains; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin Antagonists; Serotonin Receptor Agonists; Species Specificity; Transfection | 1996 |
5-hydroxytryptamine4 receptor agonists facilitate cholinergic transmission in the circular muscle of guinea pig ileum: antagonism by tropisetron and DAU 6285.
Topics: Animals; Benzimidazoles; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cisapride; Female; Guinea Pigs; Ileum; In Vitro Techniques; Indoles; Male; Muscle Contraction; Muscle, Smooth; Piperidines; Receptors, Cholinergic; Receptors, Serotonin; Scopolamine; Serotonin; Synaptic Transmission; Tetrodotoxin; Tropisetron | 1992 |
Characterization of a novel 5-HT4 receptor antagonist of the azabicycloalkyl benzimidazolone class: DAU 6285.
Topics: Animals; Benzamides; Benzimidazoles; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Cyclic AMP; Embryo, Mammalian; Heart Rate; Indoles; Kinetics; Mesencephalon; Mice; Rats; Receptors, Serotonin; Reflex; Serotonin; Serotonin Antagonists; Stimulation, Chemical; Tropisetron | 1992 |
The influence of neuronal 5-hydroxytryptamine receptor antagonists on non-cholinergic ganglionic transmission in the guinea-pig enteric excitatory reflex.
Topics: Animals; Benzamides; Benzimidazoles; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Female; Guinea Pigs; Indoles; Intestine, Small; Male; Methiothepin; Muscle Contraction; Ondansetron; Serotonin Antagonists; Synaptic Transmission; Tropisetron | 1992 |
DAU 6285: a novel antagonist at the putative 5-HT4 receptor.
Topics: Animals; Benzimidazoles; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Indoles; Male; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Serotonin Antagonists; Tropisetron | 1992 |
Effect of a series of 5-HT4 receptor agonists and antagonists on steroid secretion by the adrenal gland in vitro.
Topics: Adrenal Glands; Aldosterone; Animals; Benzamides; Benzimidazoles; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Corticosterone; Dose-Response Relationship, Drug; Indoles; Male; Radioligand Assay; Ranidae; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Stereoisomerism; Structure-Activity Relationship; Sulfonamides; Tropisetron | 1994 |