darunavir has been researched along with telaprevir in 4 studies
| Studies (darunavir) | Trials (darunavir) | Recent Studies (post-2010) (darunavir) | Studies (telaprevir) | Trials (telaprevir) | Recent Studies (post-2010) (telaprevir) |
|---|---|---|---|---|---|
| 1,148 | 224 | 780 | 985 | 136 | 835 |
| Protein | Taxonomy | darunavir (IC50) | telaprevir (IC50) |
|---|---|---|---|
| NS3 protease | 0.9757 | ||
| Cathepsin L2 | Homo sapiens (human) | 1.35 | |
| Prothrombin | Homo sapiens (human) | 1 | |
| Plasminogen | Homo sapiens (human) | 8.7 | |
| Procathepsin L | Homo sapiens (human) | 3.5 | |
| Cathepsin B | Homo sapiens (human) | 2.3033 | |
| Neutrophil elastase | Homo sapiens (human) | 5.56 | |
| Chymase | Homo sapiens (human) | 0.026 | |
| Cathepsin S | Homo sapiens (human) | 0.3 | |
| Cathepsin K | Homo sapiens (human) | 0.63 | |
| Chymotrypsin-like elastase family member 1 | Homo sapiens (human) | 0.03 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Marsault, E; Peterson, ML | 1 |
| Chen, J; Gao, K; Huang, F; Tepe, JJ; Wang, R; Wei, GW | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Crespo, M; Curran, A; Guiu, JM; Ribera, E | 1 |
1 review(s) available for darunavir and telaprevir
| Article | Year |
|---|---|
Macrocycles are great cycles: applications, opportunities, and challenges of synthetic macrocycles in drug discovery.
Topics: Amino Acid Sequence; Animals; Cyclization; Drug Discovery; Enzyme Inhibitors; Humans; Macrocyclic Compounds; Protein Binding; Receptors, G-Protein-Coupled | 2011 |
3 other study(ies) available for darunavir and telaprevir
| Article | Year |
|---|---|
Perspectives on SARS-CoV-2 Main Protease Inhibitors.
Topics: Antiviral Agents; Coronavirus 3C Proteases; Humans; Protease Inhibitors | 2021 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Darunavir and telaprevir drug interaction: total and unbound plasma concentrations in HIV/HCV-coinfected patients with cirrhosis.
Topics: Antiviral Agents; Darunavir; Drug Interactions; Female; Hepatitis C, Chronic; HIV Infections; Humans; Liver Cirrhosis; Male; Middle Aged; Oligopeptides; Plasma; Sulfonamides | 2014 |