Compounds > darunavir
Page last updated: 2024-09-05

darunavir and tacrolimus

darunavir has been researched along with tacrolimus in 7 studies

Compound Research Comparison

Studies
(darunavir)		Trials
(darunavir)		Recent Studies (post-2010)
(darunavir)		Studies
(tacrolimus)		Trials
(tacrolimus)		Recent Studies (post-2010) (tacrolimus)
1,14822478017,7572,3196,661

Protein Interaction Comparison

ProteinTaxonomydarunavir (IC50)tacrolimus (IC50)
Bile salt export pumpHomo sapiens (human)7.18
Cytochrome P450 3A4Homo sapiens (human)0.58
Cytochrome P450 3A5Homo sapiens (human)0.385
Serine/threonine-protein kinase mTORHomo sapiens (human)0.0021
Peptidyl-prolyl cis-trans isomerase FKBP1AHomo sapiens (human)0.2547
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoformHomo sapiens (human)0.0148
Splicing factor 3B subunit 3Homo sapiens (human)0.0123
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)3.3
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)3.7

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's2 (28.57)24.3611
2020's4 (57.14)2.80

Authors

AuthorsStudies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Battegay, M; Marzolini, C; Mayr, M; Mertz, D1
Hamid, M; McGowan, M; Meaney, CJ; O'Connor, M; Su, W1
Cravedi, P; Degli Antoni, A; Delsante, M; Fiaccadori, E; Gandolfini, I; Maggiore, U; Manenti, L; Peruzzi, L; Riella, LV; Zaza, G1
Bagalà, A; Bartiromo, M; Bartoloni, A; Borchi, B; Botta, A; Bresci, S; Cavallo, A; Cirami, C; Cutruzzulà, R; Larti, A; Lugli, G; Tilli, M; Vaglio, A; Xhaferi, B1
Bazzoli, F; Cescon, M; Cristini, F; Dajti, E; Tamanini, G; Tamè, M1

Reviews

1 review(s) available for darunavir and tacrolimus

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

6 other study(ies) available for darunavir and tacrolimus

ArticleYear
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Drug-drug interaction in a kidney transplant recipient receiving HIV salvage therapy and tacrolimus.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2009, Volume: 54, Issue:1

    Topics: Adult; Anti-Retroviral Agents; Darunavir; Dose-Response Relationship, Drug; Drug Interactions; HIV Infections; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Protease Inhibitors; Ritonavir; Salvage Therapy; Sulfonamides; Tacrolimus

2009
Treatment of prolonged tacrolimus toxicity using phenytoin in a haemodialysis patient.
    Journal of clinical pharmacy and therapeutics, 2019, Volume: 44, Issue:4

    Topics: Darunavir; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Humans; Immunosuppressive Agents; Male; Middle Aged; Phenytoin; Renal Dialysis; Ritonavir; Tacrolimus

2019
COVID-19 in kidney transplant recipients.
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2020, Volume: 20, Issue:7

    Topics: Aged; Betacoronavirus; Cobicistat; Colchicine; Coronavirus Infections; COVID-19; Cytokines; Darunavir; Drug Combinations; Female; Humans; Hydroxychloroquine; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Transplantation; Lopinavir; Male; Middle Aged; Mycophenolic Acid; Pandemics; Pneumonia, Viral; Ritonavir; SARS-CoV-2; Tacrolimus; Transplant Recipients; Treatment Outcome

2020
Threatening drug-drug interaction in a kidney transplant patient with coronavirus disease 2019 (COVID-19).
    Transplant infectious disease : an official journal of the Transplantation Society, 2020, Volume: 22, Issue:4

    Topics: Adult; Antiviral Agents; Betacoronavirus; C-Reactive Protein; Ciliopathies; Cobicistat; Common Cold; Coronavirus Infections; Cough; COVID-19; COVID-19 Drug Treatment; Cytochrome P-450 CYP3A Inhibitors; Darunavir; Deprescriptions; Drug Combinations; Drug Interactions; Enzyme Inhibitors; Fatigue; Female; Glucocorticoids; Graft Rejection; Humans; Hydroxychloroquine; Immunocompromised Host; Immunosuppressive Agents; Interleukin-10; Interleukin-1beta; Interleukin-6; Interleukin-8; Kidney Diseases, Cystic; Kidney Failure, Chronic; Kidney Transplantation; Leber Congenital Amaurosis; Lopinavir; Methylprednisolone; Optic Atrophies, Hereditary; Pandemics; Pneumonia, Viral; Ritonavir; SARS-CoV-2; Severity of Illness Index; Tacrolimus

2020
COVID-19 in a young liver transplant recipient: caution for drug-drug interactions.
    Journal of gastrointestinal and liver diseases : JGLD, 2020, 09-09, Volume: 29, Issue:3

    Topics: Acute Kidney Injury; Adult; Antiviral Agents; Betacoronavirus; Clinical Laboratory Techniques; Coronavirus Infections; COVID-19; COVID-19 Testing; Darunavir; Drug Interactions; Drug Monitoring; Humans; Hydroxychloroquine; Immunosuppressive Agents; Liver Transplantation; Male; Pandemics; Pneumonia, Viral; Prednisone; Risk Adjustment; Ritonavir; SARS-CoV-2; Tacrolimus; Transplant Recipients; Treatment Outcome

2020