darunavir has been researched along with pravastatin in 3 studies
| Studies (darunavir) | Trials (darunavir) | Recent Studies (post-2010) (darunavir) | Studies (pravastatin) | Trials (pravastatin) | Recent Studies (post-2010) (pravastatin) |
|---|---|---|---|---|---|
| 1,148 | 224 | 780 | 3,575 | 1,036 | 816 |
| Protein | Taxonomy | darunavir (IC50) | pravastatin (IC50) |
|---|---|---|---|
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Homo sapiens (human) | 0.1452 | |
| Insulin receptor | Rattus norvegicus (Norway rat) | 0.0056 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 0.0056 | |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Rattus norvegicus (Norway rat) | 0.0254 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 3.6 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Anderson, PL; Aquilante, CL; Christians, U; Daily, EB; Hoffman, KL; Hopley, CW; Kiser, JJ; Kosmiski, LA; Predhomme, JA; Schniedewind, B; Sidhom, MS | 1 |
| Afonso, P; Auclair, M; Capeau, J; Capel, E; Caron-Debarle, M | 1 |
1 review(s) available for darunavir and pravastatin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for darunavir and pravastatin
| Article | Year |
|---|---|
Influence of SLCO1B1 polymorphisms on the drug-drug interaction between darunavir/ritonavir and pravastatin.
Topics: Adult; Cholesterol; Darunavir; Drug Interactions; Female; Haplotypes; HIV Protease Inhibitors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver-Specific Organic Anion Transporter 1; Male; Middle Aged; Organic Anion Transporters; Polymorphism, Genetic; Pravastatin; Ritonavir; Sulfonamides; Triglycerides | 2012 |
1 other study(ies) available for darunavir and pravastatin
| Article | Year |
|---|---|
Impact of darunavir, atazanavir and lopinavir boosted with ritonavir on cultured human endothelial cells: beneficial effect of pravastatin.
Topics: Anti-HIV Agents; Atazanavir Sulfate; Cells, Cultured; Cellular Senescence; Darunavir; Drug Synergism; Endothelial Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lopinavir; Nitric Oxide; Oligopeptides; Oxidative Stress; Pravastatin; Pyridines; Ritonavir; Sulfonamides | 2014 |