Page last updated: 2024-09-05

darunavir and omeprazole

darunavir has been researched along with omeprazole in 3 studies

Compound Research Comparison

Studies
(darunavir)
Trials
(darunavir)
Recent Studies (post-2010)
(darunavir)
Studies
(omeprazole)
Trials
(omeprazole)
Recent Studies (post-2010) (omeprazole)
1,1482247809,0852,7371,487

Protein Interaction Comparison

ProteinTaxonomydarunavir (IC50)omeprazole (IC50)
Mcl-1Homo sapiens (human)3.1448
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)0.28
Potassium-transporting ATPase alpha chain 1Homo sapiens (human)1.45
Cytochrome P450 2C19Homo sapiens (human)2.315
Potassium-transporting ATPase subunit betaHomo sapiens (human)1.45
WD repeat-containing protein 5Homo sapiens (human)1.7
Glutathione S-transferase omega-1Homo sapiens (human)4.6
Histone-lysine N-methyltransferase 2AHomo sapiens (human)1.7
Muscarinic acetylcholine receptorCavia porcellus (domestic guinea pig)3.8

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
De Marez, T; De Paepe, E; De Pauw, M; Hoetelmans, RM; Lefebvre, E; Parys, W; Sekar, VJ1

Reviews

1 review(s) available for darunavir and omeprazole

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for darunavir and omeprazole

ArticleYear
Pharmacokinetic interaction between darunavir boosted with ritonavir and omeprazole or ranitidine in human immunodeficiency virus-negative healthy volunteers.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:3

    Topics: Adolescent; Adult; Anti-HIV Agents; Anti-Ulcer Agents; Antiviral Agents; Area Under Curve; Darunavir; Drug Interactions; Female; Histamine H2 Antagonists; Humans; Male; Middle Aged; Omeprazole; Ranitidine; Ritonavir; Sulfonamides

2007

Other Studies

1 other study(ies) available for darunavir and omeprazole

ArticleYear
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023