darunavir has been researched along with elacridar in 2 studies
| Studies (darunavir) | Trials (darunavir) | Recent Studies (post-2010) (darunavir) | Studies (elacridar) | Trials (elacridar) | Recent Studies (post-2010) (elacridar) |
|---|---|---|---|---|---|
| 1,148 | 224 | 780 | 284 | 8 | 119 |
| Protein | Taxonomy | darunavir (IC50) | elacridar (IC50) |
|---|---|---|---|
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 0.4427 | |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 0.2852 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Annaert, P; Augustijns, P; Baes, M; Gonzalez, FJ; Holmstock, N | 1 |
2 other study(ies) available for darunavir and elacridar
| Article | Year |
|---|---|
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
PXR/CYP3A4-humanized mice for studying drug-drug interactions involving intestinal P-glycoprotein.
Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytochrome P-450 CYP3A; Darunavir; Drug Interactions; Humans; Intestinal Absorption; Intestinal Mucosa; Intestines; Male; Mice; Mice, Transgenic; Models, Animal; Pregnane X Receptor; Receptors, Steroid; Rifampin; Sulfonamides; Tetrahydroisoquinolines; Xenobiotics | 2013 |