darunavir has been researched along with brecanavir in 4 studies
| Studies (darunavir) | Trials (darunavir) | Recent Studies (post-2010) (darunavir) | Studies (brecanavir) | Trials (brecanavir) | Recent Studies (post-2010) (brecanavir) |
|---|---|---|---|---|---|
| 1,148 | 224 | 780 | 12 | 3 | 2 |
| Protein | Taxonomy | darunavir (IC50) | brecanavir (IC50) |
|---|---|---|---|
| Chain A, Gag-Pol polyprotein | Human immunodeficiency virus 1 | 0.0028 | |
| Chain B, Gag-Pol polyprotein | Human immunodeficiency virus 1 | 0.0028 | |
| Chain A, Gag-Pol polyprotein | Human immunodeficiency virus 1 | 0.0028 | |
| Chain B, Gag-Pol polyprotein | Human immunodeficiency virus 1 | 0.0028 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andrews, CW; Brieger, M; Furfine, ES; Hale, MR; Hanlon, MH; Hazen, RJ; Kaldor, I; McLean, EW; Miller, JF; Reynolds, D; Sammond, DM; Sherrill, RG; Spaltenstein, A; Tung, R; Turner, EM; Xu, RX | 1 |
| Boone, L; Craig, C; Ferris, R; Furfine, E; Griffin, P; Hale, M; Hanlon, M; Harvey, R; Hazen, R; Kaldor, I; Miller, J; Ray, J; Samano, V; Spaltenstein, A; St Clair, M; Tung, R; Yates, P | 1 |
| Amano, M; Baldridge, A; Das, D; Davis, DA; Ghosh, AK; Koh, Y; Leschenko, S; Li, J; Matsumi, S; Mitsuya, H; Shioda, T; Yarchoan, R | 1 |
| Babusis, D; Bhoopathy, S; Hidalgo, IJ; Phan, TK; Ray, AS; Rhodes, GR; Robinson, KL; Strab, R; Tong, L | 1 |
4 other study(ies) available for darunavir and brecanavir
| Article | Year |
|---|---|
Ultra-potent P1 modified arylsulfonamide HIV protease inhibitors: the discovery of GW0385.
Topics: HIV Protease Inhibitors; Molecular Structure; Sulfonamides | 2006 |
In vitro antiviral activity of the novel, tyrosyl-based human immunodeficiency virus (HIV) type 1 protease inhibitor brecanavir (GW640385) in combination with other antiretrovirals and against a panel of protease inhibitor-resistant HIV.
Topics: Algorithms; Anti-Retroviral Agents; Benzodioxoles; Blood Proteins; Carbamates; Cell Line; Drug Resistance, Viral; HeLa Cells; HIV Protease Inhibitors; HIV-1; Humans; Orosomucoid; Phenotype; Serum; Serum Albumin; Tyrosine | 2007 |
Potent inhibition of HIV-1 replication by novel non-peptidyl small molecule inhibitors of protease dimerization.
Topics: Animals; CCR5 Receptor Antagonists; CD4 Antigens; Chlorocebus aethiops; COS Cells; Darunavir; Dimerization; Dose-Response Relationship, Drug; Enzyme Activation; Fluorescence Resonance Energy Transfer; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Protein Processing, Post-Translational; Pyridines; Pyrones; Receptors, CCR5; Sulfonamides; Virus Replication | 2007 |
Effects of human immunodeficiency virus protease inhibitors on the intestinal absorption of tenofovir disoproxil fumarate in vitro.
Topics: Adenine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Cell Line; Chromatography, High Pressure Liquid; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Drug Interactions; Epithelium; HIV Protease Inhibitors; Humans; Hydrolysis; Indicators and Reagents; Intestinal Absorption; Mass Spectrometry; Organophosphonates; Subcellular Fractions; Tenofovir | 2007 |