darifenacin and sibenadet

darifenacin has been researched along with sibenadet* in 1 studies

Other Studies

1 other study(ies) available for darifenacin and sibenadet

Article	Year
Design-driven LO: the discovery of new ultra long acting dibasic β2-adrenoceptor agonists. Bioorganic & medicinal chemistry letters, 2011, Aug-01, Volume: 21, Issue:15 Starting with the molecular scaffold of the DA(2)/β(2) dual agonist sibenadet (Viozan™), a number of molecular changes were incorporated, which were designed to increase the potency and selectivity of the target molecule, and improve its pharmacokinetics. Through this process a novel, high potency, full β(2)-agonist with high selectivity and long duration capable of being dosed once daily has been discovered. Topics: Adrenergic beta-2 Receptor Agonists; Animals; Bronchodilator Agents; Drug Design; Drug Evaluation, Preclinical; Guinea Pigs; Receptors, Adrenergic, beta-2; Structure-Activity Relationship; Thiazoles	2011

Article

Year

Design-driven LO: the discovery of new ultra long acting dibasic β2-adrenoceptor agonists.

Bioorganic & medicinal chemistry letters, 2011, Aug-01, Volume: 21, Issue:15

Starting with the molecular scaffold of the DA(2)/β(2) dual agonist sibenadet (Viozan™), a number of molecular changes were incorporated, which were designed to increase the potency and selectivity of the target molecule, and improve its pharmacokinetics. Through this process a novel, high potency, full β(2)-agonist with high selectivity and long duration capable of being dosed once daily has been discovered.

Topics: Adrenergic beta-2 Receptor Agonists; Animals; Bronchodilator Agents; Drug Design; Drug Evaluation, Preclinical; Guinea Pigs; Receptors, Adrenergic, beta-2; Structure-Activity Relationship; Thiazoles

2011