dapsone and trimethoprim

dapsone has been researched along with trimethoprim in 101 studies

Research

Studies (101)

TimeframeStudies, this research(%)All Research%
pre-199043 (42.57)18.7374
1990's27 (26.73)18.2507
2000's15 (14.85)29.6817
2010's16 (15.84)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Genther, CS; Smith, CS1
Queener, SF1
Doman, TN; McGovern, SL; Seidler, J; Shoichet, BK1
Bartels, R; Hänsel, W; Kunz, B; Lehwark-Yvetot, G; Otzen, T; Schaper, KJ; Seydel, JK; Wempe, EG1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Bury, L; Caspers, P; Gaucher, B; Heim, J; Schmitt-Hoffmann, A; Shapiro, S; Siegrist, S; Thenoz, L; Urwyler, H1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Bera, S; Mondal, D1
Hlaing, N; Htun Nyun, R; Kyi, KK; Myint, T; Tin, F; U, T1
Kakande, I1
Davidson, DE; Hickman, RL; Johnsen, DO; Kinnamon, KE; Tanticharoenyos, P1
Havas, L1
Coleman, MD; Park, BK; Russell, RM; Tingle, MD1
Laifer, G; Rüttimann, S1
Feinberg, J; Sattler, FR1
Costantino, M1
Kwok, RY; Lambertus, MW; Mulligan, ME1
Dhople, AM; Jagannathan, R; Mahadevan, PR; Rosenfeld, M; Seydel, JK; Wempe, EG1
Crosby, WH1
Benowitz, N; Hopewell, PC; Lee, B; Leoung, G; Medina, I; Mills, J; Modin, G; Wofsy, CB1
Montgomery, AB2
Girard, PM1
Benowitz, NL; Jacob, P; Lee, BL; Medina, I; Mills, J; Wofsy, CB1
Durfee, D; Kurtin, PJ; McKinsey, DS1
Hopewell, PC; Hughes, W; Leoung, GS; Mills, J; Wofsy, C1
Kovacs, JA; Masur, H1
Fischl, MA1
Hauptman, SP; Wordell, CJ1
Clarkson, AB; Rosenberg, C; Williams, DE1
Cushion, MT; Foy, JM; Kim, CK; Linke, MJ; Walzer, PD1
Hughes, WT1
Hopewell, PC; Hughes, WT; Leoung, G; Medina, I; Mills, J; Wofsy, C1
Christie, PR; Goldberg, DJ; Green, ST; Kennedy, DH; Leach, J1
el Sid, MA; Gumaa, SA; Mahgoub, ES1
Hughes, WT; Jacobus, DP; Smith, BL1
Andrade, R; Bonifaz, A; Messina, M; Saúl, A1
Himmunknan, P; Piamphongsant, T; Sirimachan, S1
Edelson, PJ; Friedman-Kien, A; Metroka, CE1
Catterall, JR; Potasman, I; Remington, JS1
Cushion, MT; Linke, MJ; Stanforth, D; Walzer, PD1
Vischer, WA1
Bowman, JE; Carson, PE; Frischer, H; Kass, L; Richard, L; Rieckmann, KH; Willerson, D1
Geiman, QM; Schnell, JV; Siddiqui, WA1
Freerksen, E; Rosenfeld, M2
Rohde, R1
Botelho, A1
Botha, D1
Laing, AB1
Hughes, WT; Smith, BL1
Rosenfeld, M; Seydel, JK; Wempe, EG1
Biagini, RE; Martínez, TE; Museli, A; Sarmiento Villa, H1
Richter, M; Seydel, JK; Wempe, E1
Dankert, W; Hartman, PG; Mehlhorn, H; Then, RL1
Hughes, WT; Killmar, JT; Oz, HS1
Arsenijevic, D; Chang, HR; Comte, R; Pechère, JC; Polak, A; Then, RL1
Lizasoain, M; Lumbreras, C; Pastor, C1
Glick, M; Muzyka, BC1
Seydel, JK1
Foy, J; Steele, P; Walzer, PD; White, M1
Lang, W; Moss, A; Osmond, D; Page-Bodkin, K; Winkelstein, W1
Fraser-Smith, EB; Freitas, VR; Matthews, TR1
Kuster, H; Lüthy, R; Opravil, M; Russi, EW; Siegenthaler, W; Speich, R; Teuscher, AU; Theiler, R1
Allegra, CJ; Kovacs, JA; Martinez, A1
Korraa, H; Saadeh, C1
Gambertoglio, JG; Lee, BL; Makrides, V; Safrin, S1
Angehrn, P; Hartman, PG; Locher, HH; Schlunegger, H; Then, RL1
Brun-Pascaud, M; Chau, F; Derouin, F; Garry, L; Girard, PM; Jacobus, D1
Bernauer, W; Font, RL; Messmer, EP; Moll, C; Ruggli, GM; Weber, R1
Dhople, AM3
McPartlin, DW; Patel, SK; Philpott, JM1
Antin, JH; Bernardo, MV; King, C; Vasconcelles, MJ; Weller, EA1
Beard, CB; Carter, JL; del Rio, C; Hightower, A; Huang, L; Le, T; Lee, S; Navin, TR; Pieniazek, NJ; Rimland, D1
Elmahallawy, M; Horsfield, C; Praveen, CV; Terry, RM1
Atzori, C; Benfield, T; Crothers, K; Helweg-Larsen, J; Huang, L; Miller, R; Rabodonirina, M1
Bellamy, R1
Mannion, C; McDonald, M; Rafter, P1
Giordano, TP; Serpa, JA; Villarreal-Williams, E1
Botitsi, E; Economou, A; Petraki, O; Tsipi, D1
Brandão, MAF; Ferreira, AO; Patrício, FB; Polonini, HC; Raposo, NRB; Silva, SL1
Bilandžić, N; Božić, Đ; Kolanović, BS; Sedak, M; Varenina, I; Varga, I; Đokić, M1

Reviews

15 review(s) available for dapsone and trimethoprim

ArticleYear
New drug developments for opportunistic infections in immunosuppressed patients: Pneumocystis carinii.
    Journal of medicinal chemistry, 1995, Nov-24, Volume: 38, Issue:24

    Topics: Animals; Drug Design; Humans; Immunosuppression Therapy; Molecular Structure; Opportunistic Infections; Pneumonia, Pneumocystis; Structure-Activity Relationship

1995
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Insights of synthetic analogues of anti-leprosy agents.
    Bioorganic & medicinal chemistry, 2019, 07-01, Volume: 27, Issue:13

    Topics: Humans; Leprostatic Agents; Leprosy; Structure-Activity Relationship

2019
Recent developments in the therapy and management of Pneumocystis carinii pneumonia in patients with AIDS.
    AIDS clinical review, 1989

    Topics: Acquired Immunodeficiency Syndrome; Dapsone; Drug Therapy, Combination; Humans; Pentamidine; Pneumonia, Pneumocystis; Quinazolines; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Trimetrexate

1989
Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome: pathophysiology, therapy, and prevention.
    Seminars in respiratory infections, 1989, Volume: 4, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Aerosols; Dapsone; Diet; Drug Combinations; Humans; Oxygen Inhalation Therapy; Pentamidine; Pneumonia, Pneumocystis; Sulfamethoxazole; Trimethoprim

1989
Pneumocystis carinii pneumonia: therapy and prophylaxis.
    The Journal of infectious diseases, 1988, Volume: 158, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Anti-Bacterial Agents; Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Pentamidine; Pneumonia, Pneumocystis; Pyrimethamine; Quinazolines; Recurrence; Sulfadiazine; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Trimetrexate

1988
Treatment and prophylaxis of Pneumocystis carinii pneumonia.
    AIDS (London, England), 1988, Volume: 2 Suppl 1

    Topics: Acquired Immunodeficiency Syndrome; Adrenal Cortex Hormones; Antiprotozoal Agents; Clinical Trials as Topic; Dapsone; Drug Combinations; Humans; Pentamidine; Pneumonia, Pneumocystis; Quinazolines; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Trimetrexate; Zidovudine

1988
Prevention of Pneumocystis carinii pneumonia.
    The Medical letter on drugs and therapeutics, 1988, Oct-07, Volume: 30, Issue:776

    Topics: Acquired Immunodeficiency Syndrome; Aerosols; Dapsone; Drug Combinations; Humans; Pentamidine; Pneumonia, Pneumocystis; Pyrimethamine; Recurrence; Sulfadoxine; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1988
[Current alternatives in the treatment of Pneumocystis carinii pneumonia in patients with AIDS].
    Medicina clinica, 1994, Oct-15, Volume: 103, Issue:12

    Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Atovaquone; Clindamycin; Dapsone; Eflornithine; Humans; Naphthoquinones; Pneumonia, Pneumocystis; Primaquine; Trimethoprim; Trimetrexate

1994
In vitro and in vivo results of brodimoprim and analogues alone and in combination against E. coli and mycobacteria.
    Journal of chemotherapy (Florence, Italy), 1993, Volume: 5, Issue:6

    Topics: Dapsone; Dihydropteroate Synthase; Escherichia coli; Escherichia coli Infections; Humans; Leprosy; Mycobacterium; Mycobacterium Infections; Tetrahydrofolate Dehydrogenase; Trimethoprim

1993
Options in the management of pneumonia caused by Pneumocystis carinii in patients with acquired immune deficiency syndrome and intolerance to trimethoprim/sulfamethoxazole.
    Southern medical journal, 1996, Volume: 89, Issue:3

    Topics: Adrenal Cortex Hormones; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antifungal Agents; Atovaquone; Clindamycin; Dapsone; Drug Combinations; Drug Hypersensitivity; Drug Resistance, Microbial; Humans; Leucovorin; Naphthoquinones; Pentamidine; Pneumonia, Pneumocystis; Primaquine; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Trimetrexate

1996
An unusual case of Pneumocystis carinii presenting as an aural mass.
    The Journal of laryngology and otology, 1999, Volume: 113, Issue:6

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Dapsone; Drug Therapy, Combination; Ear Diseases; Ear, External; Humans; Magnetic Resonance Imaging; Male; Pneumocystis; Pneumocystis Infections; Tomography, X-Ray Computed; Trimethoprim

1999
Pneumocystis carinii infection in bilateral aural polyps in a human immunodeficiency virus-positive patient.
    The Journal of laryngology and otology, 2002, Volume: 116, Issue:4

    Topics: Adult; AIDS-Related Opportunistic Infections; Antifungal Agents; Dapsone; Ear Neoplasms; Ear, Middle; Humans; Male; Pneumocystis Infections; Polyps; Sulfamethoxazole; Tomography, X-Ray Computed; Trimethoprim

2002
Dihydropteroate synthase gene mutations in Pneumocystis and sulfa resistance.
    Emerging infectious diseases, 2004, Volume: 10, Issue:10

    Topics: Anti-Infective Agents; Dapsone; Dihydropteroate Synthase; Drug Resistance, Fungal; Gene Expression; Humans; Mutation; Pneumocystis carinii; Pneumonia, Pneumocystis; Risk Factors; Sulfamethoxazole; Sulfones; Trimethoprim

2004
Pneumocystis pneumonia in people with HIV.
    Clinical evidence, 2006, Issue:15

    Topics: Anti-Infective Agents; Antiprotozoal Agents; Atovaquone; Clindamycin; Dapsone; Drug Therapy, Combination; HIV Infections; Humans; Pentamidine; Pneumonia, Pneumocystis; Primaquine; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

2006

Trials

9 trial(s) available for dapsone and trimethoprim

ArticleYear
Chloroquine-resistant malaria in Burma.
    The Journal of tropical medicine and hygiene, 1975, Volume: 78, Issue:8

    Topics: Chloroquine; Clinical Trials as Topic; Dapsone; Drug Resistance, Microbial; Humans; Malaria; Myanmar; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine; Sulfamethoxypyridazine; Trimethoprim

1975
[Successful treatment of HIV-associated pneumocystis carinii pneumonia with dapsone plus trimethoprim].
    Wiener klinische Wochenschrift, 1992, Volume: 104, Issue:18

    Topics: Administration, Oral; Adult; AIDS-Related Opportunistic Infections; Ambulatory Care; Dapsone; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Pneumonia, Pneumocystis; Prospective Studies; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1992
Oral therapy for Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome. A controlled trial of trimethoprim-sulfamethoxazole versus trimethoprim-dapsone.
    The New England journal of medicine, 1990, Sep-20, Volume: 323, Issue:12

    Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; Chemical and Drug Induced Liver Injury; Dapsone; Double-Blind Method; Drug Combinations; Female; Humans; Male; Neutropenia; Pentamidine; Pneumonia, Pneumocystis; Random Allocation; Survival Rate; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1990
Dapsone, trimethoprim, and sulfamethoxazole plasma levels during treatment of Pneumocystis pneumonia in patients with the acquired immunodeficiency syndrome (AIDS). Evidence of drug interactions.
    Annals of internal medicine, 1989, Apr-15, Volume: 110, Issue:8

    Topics: Acetylation; Acquired Immunodeficiency Syndrome; Adult; Dapsone; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Phenotype; Pneumonia, Pneumocystis; Prospective Studies; Random Allocation; Sulfamethoxazole; Trimethoprim

1989
Treatment and prophylaxis of Pneumocystis carinii pneumonia.
    AIDS (London, England), 1988, Volume: 2 Suppl 1

    Topics: Acquired Immunodeficiency Syndrome; Adrenal Cortex Hormones; Antiprotozoal Agents; Clinical Trials as Topic; Dapsone; Drug Combinations; Humans; Pentamidine; Pneumonia, Pneumocystis; Quinazolines; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Trimetrexate; Zidovudine

1988
Pneumocystis carinii pneumonia in the patient with AIDS.
    Chest, 1985, Volume: 88, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Animals; Bronchoscopy; Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Therapy, Combination; Eflornithine; Humans; Male; Ornithine; Pentamidine; Pneumocystis; Pneumonia, Pneumocystis; Pyrimethamine; Sulfadiazine; Sulfamethoxazole; Therapeutic Irrigation; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1985
Combinations of 4-aminobenzoic acid competitors and dihydrofolate dehydrogenase inhibitors in the chemotherapy of malaria. A commentary.
    Bulletin of the World Health Organization, 1974, Volume: 50, Issue:3-4

    Topics: Africa; Antimalarials; Asia; Chloroquine; Clinical Trials as Topic; Dapsone; Drug Evaluation; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Folic Acid Antagonists; Humans; Malaria; Pyrimethamine; Trimethoprim

1974
Zidovudine, trimethoprim, and dapsone pharmacokinetic interactions in patients with human immunodeficiency virus infection.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Adult; Dapsone; Drug Combinations; Humans; Male; Trimethoprim; Zidovudine

1996
Aerosolized pentamidine as pneumocystis prophylaxis after bone marrow transplantation is inferior to other regimens and is associated with decreased survival and an increased risk of other infections.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2000, Volume: 6, Issue:1

    Topics: Administration, Inhalation; Adolescent; Adult; Aerosol Propellants; Aged; Antifungal Agents; Bone Marrow Transplantation; Cohort Studies; Combined Modality Therapy; Dapsone; Drug Evaluation; Female; Graft vs Host Disease; Hematologic Neoplasms; Humans; Infections; Male; Middle Aged; Pentamidine; Pneumocystis Infections; Retrospective Studies; Sulfamethoxazole; Survival Rate; Trimethoprim

2000

Other Studies

78 other study(ies) available for dapsone and trimethoprim

ArticleYear
Antifolate studies. Activities of 40 potential antimalarial compounds against sensitive and chlorguanide triazine resistant strains of folate-requiring bacteria and Escherichia coli.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:2

    Topics: Animals; Antimalarials; Bacteria; Drug Resistance, Microbial; Escherichia coli; Folic Acid; Folic Acid Antagonists; Malaria; Mice; Plasmodium berghei; Triazines

1977
Identification and prediction of promiscuous aggregating inhibitors among known drugs.
    Journal of medicinal chemistry, 2003, Oct-09, Volume: 46, Issue:21

    Topics: Antifungal Agents; beta-Lactamase Inhibitors; Chemical Phenomena; Chemistry, Physical; Chymotrypsin; Enzyme Inhibitors; Kinetics; Light; Malate Dehydrogenase; Models, Molecular; Molecular Conformation; Scattering, Radiation; Structure-Activity Relationship

2003
Folate-synthesizing enzyme system as target for development of inhibitors and inhibitor combinations against Candida albicans-synthesis and biological activity of new 2,4-diaminopyrimidines and 4'-substituted 4-aminodiphenyl sulfones.
    Journal of medicinal chemistry, 2004, Jan-01, Volume: 47, Issue:1

    Topics: Aminopyridines; Animals; Antifungal Agents; Candida albicans; Dihydropteroate Synthase; Drug Combinations; Drug Resistance, Multiple, Fungal; Folic Acid Antagonists; Microbial Sensitivity Tests; Mutation; Quantitative Structure-Activity Relationship; Rats; Sulfones; Tetrahydrofolate Dehydrogenase

2004
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
In vitro and in vivo properties of dihydrophthalazine antifolates, a novel family of antibacterial drugs.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:9

    Topics: Animals; Anti-Bacterial Agents; Cell Survival; Enterococcus; Folic Acid Antagonists; Haemophilus influenzae; HeLa Cells; Humans; Male; Mice; Microbial Sensitivity Tests; Molecular Structure; Moraxella catarrhalis; Mycobacterium avium; Phthalazines; Polymerase Chain Reaction; Streptococcus pneumoniae; Tetrahydrofolate Dehydrogenase; Trimethoprim

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Treatment of mycetoma.
    Lancet (London, England), 1977, Jul-02, Volume: 2, Issue:8027

    Topics: Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Mycetoma; Streptomycin; Sulfamethoxazole; Trimethoprim

1977
Treatment of mycetoma with a combination of dapsone and co-trimoxazole.
    East African medical journal, 1979, Volume: 56, Issue:2

    Topics: Adult; Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Male; Mycetoma; Sulfamethoxazole; Trimethoprim

1979
Evaluating new antimalarial drugs against trophozoite induced Plasmodium cynomolgi malaria in rhesus monkeys.
    The American journal of tropical medicine and hygiene, 1976, Volume: 25, Issue:1

    Topics: Amodiaquine; Animals; Antimalarials; Dapsone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Tolerance; Haplorhini; Macaca mulatta; Malaria; Phenanthrenes; Primaquine; Prodigiosin; Pyrimethamine; Quinine; Sulfadiazine; Sulfadimethoxine; Sulfalene; Trimethoprim

1976
[The treatment of various deep mycoses (South American blastomycosis, nocardiosis, actinomycetoma) with the drug combination sulfamethoxazole+trimethoprim (bactrim, septrin). Review of the literature].
    Mykosen, 1975, Volume: 18, Issue:6

    Topics: Actinomycetales; Actinomycetales Infections; Blastomyces; Blastomycosis; Dapsone; Drug Combinations; Drug Synergism; Histoplasma; Histoplasmosis; Mycoses; Nocardia; Nocardia Infections; South America; Sulfamethoxazole; Trimethoprim

1975
Inhibition of dapsone-induced methaemoglobinaemia by cimetidine in the presence of trimethoprim in the rat.
    The Journal of pharmacy and pharmacology, 1992, Volume: 44, Issue:2

    Topics: Acetylation; Animals; Cimetidine; Dapsone; Drug Interactions; Half-Life; Male; Methemoglobin; Methemoglobinemia; Rats; Rats, Inbred Strains; Trimethoprim

1992
New developments in the treatment of Pneumocystis carinii pneumonia.
    Chest, 1992, Volume: 101, Issue:2

    Topics: Adrenal Cortex Hormones; Aerosols; Dapsone; Drug Therapy, Combination; Eflornithine; Folic Acid Antagonists; Humans; Pentamidine; Pneumonia, Pneumocystis; Pyrimidines; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Trimetrexate

1992
[Some aspects of the treatment of HIV infection].
    Minerva ginecologica, 1991, Volume: 43, Issue:12

    Topics: Acquired Immunodeficiency Syndrome; Clindamycin; Dapsone; HIV Infections; Humans; Primaquine; Trimethoprim; Trimetrexate; Zidovudine

1991
In vitro susceptibilities of oxacillin-resistant Staphylococcus aureus to dapsone and sulfamethoxazole alone and in combination with trimethoprim.
    Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:7

    Topics: Dapsone; Enterococcus faecalis; Escherichia coli; Microbial Sensitivity Tests; Oxacillin; Penicillin Resistance; Staphylococcus aureus; Sulfamethoxazole; Trimethoprim

1990
In vitro and in vivo experiments with the new inhibitor of mycobacterium leprae brodimoprim alone and in combination with dapsone.
    Arzneimittel-Forschung, 1990, Volume: 40, Issue:1

    Topics: Adenosine Triphosphate; Animals; Chromatography, High Pressure Liquid; Dapsone; Drug Interactions; Leprostatic Agents; Leprosy; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mycobacterium leprae; Receptors, Fc; Thymidine; Trimethoprim

1990
Megaloblastic pancytopenia associated with dapsone and trimethoprim treatment of Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome.
    Archives of internal medicine, 1990, Volume: 150, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Anemia, Macrocytic; Anemia, Megaloblastic; Dapsone; Humans; Leucovorin; Pneumonia, Pneumocystis; Trimethoprim; Vitamin B 12 Deficiency

1990
[Treatment and prevention of pneumocystosis].
    La Revue du praticien, 1989, Dec-01, Volume: 39, Issue:28

    Topics: Acquired Immunodeficiency Syndrome; Adrenal Cortex Hormones; Anti-Bacterial Agents; Dapsone; Humans; Pneumonia, Pneumocystis; Trimethoprim

1989
Megaloblastic pancytopenia associated with dapsone and trimethoprim treatment of Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome.
    Archives of internal medicine, 1989, Volume: 149, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adult; Dapsone; Drug Therapy, Combination; Humans; Male; Pancytopenia; Pneumonia, Pneumocystis; Trimethoprim; Vitamin B 12 Deficiency

1989
Dapsone-trimethoprim for Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome.
    Annals of internal medicine, 1986, Volume: 105, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Bronchoscopy; Dapsone; Drug Eruptions; Drug Therapy, Combination; Fever; Hematocrit; Humans; Liver; Nausea; Pneumonia, Pneumocystis; Respiratory Function Tests; Sputum; Trimethoprim

1986
Treatment of Pneumocystis carinii pneumonia.
    The Medical letter on drugs and therapeutics, 1987, Nov-20, Volume: 29, Issue:753

    Topics: Acquired Immunodeficiency Syndrome; Dapsone; Drug Combinations; Folic Acid Antagonists; Humans; Methylprednisolone; Pentamidine; Pneumonia, Pneumocystis; Quinazolines; Recurrence; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Trimetrexate

1987
Treatment of Pneumocystis carinii pneumonia in patients with AIDS.
    Clinical pharmacy, 1988, Volume: 7, Issue:7

    Topics: Acquired Immunodeficiency Syndrome; Adrenal Cortex Hormones; Adult; Anti-Infective Agents; Dapsone; Drug Combinations; Eflornithine; Humans; Male; Pentamidine; Pneumonia, Pneumocystis; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1988
Efficacy of DL-alpha-difluoromethylornithine in a rat model of Pneumocystis carinii pneumonia.
    Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:8

    Topics: Amphotericin B; Animals; Antiprotozoal Agents; Dapsone; Diminazene; Disease Models, Animal; Drug Combinations; Eflornithine; Female; Immunosuppression Therapy; Pneumonia, Pneumocystis; Random Allocation; Rats; Rats, Inbred Strains; Sulfamethoxazole; Suramin; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1988
Inhibitors of folic acid synthesis in the treatment of experimental Pneumocystis carinii pneumonia.
    Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:1

    Topics: Animals; Dapsone; Drug Therapy, Combination; Folic Acid Antagonists; Immunosuppression Therapy; Male; Pneumonia, Pneumocystis; Pyrimethamine; Pyrimidines; Rats; Rats, Inbred Strains; Sulfadiazine; Sulfadoxine; Sulfamethoxazole; Trimethoprim

1988
Comparison of dosages, intervals, and drugs in the prevention of Pneumocystis carinii pneumonia.
    Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:5

    Topics: Amidines; Animals; Anti-Infective Agents; Dapsone; Drug Administration Schedule; Drug Combinations; Immunosuppression Therapy; Male; Pentamidine; Pneumonia, Pneumocystis; Rats; Rats, Inbred Strains; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1988
Dapsone treatment of Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome.
    Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:7

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Dapsone; Drug Therapy, Combination; Humans; Male; Pentamidine; Pneumonia, Pneumocystis; Sulfamethoxazole; Trimethoprim

1988
AIDS-related Pneumocystis carinii pneumonia successfully treated with dapsone-trimethoprim.
    British journal of clinical pharmacology, 1988, Volume: 26, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adult; Dapsone; Drug Therapy, Combination; Humans; Male; Pneumonia, Pneumocystis; Trimethoprim

1988
Mycetoma of the head and neck.
    The American journal of tropical medicine and hygiene, 1986, Volume: 35, Issue:3

    Topics: Actinomycetales Infections; Adolescent; Adult; Child; Dapsone; Drug Combinations; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Mitosporic Fungi; Mycetoma; Radiography; Skull; Streptomycin; Sudan; Sulfamethoxazole; Temporomandibular Joint; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1986
Successful treatment and prevention of murine Pneumocystis carinii pneumonitis with 4,4'-sulfonylbisformanilide.
    Antimicrobial agents and chemotherapy, 1986, Volume: 29, Issue:3

    Topics: Animals; Dapsone; Dexamethasone; Drug Combinations; Pneumonia, Pneumocystis; Rats; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1986
Mycetoma due to Nocardia caviae.
    International journal of dermatology, 1987, Volume: 26, Issue:3

    Topics: Dapsone; Drug Combinations; Humans; Male; Middle Aged; Mycetoma; Nocardia Infections; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1987
Juvenile blistering diseases: the problems of diagnosis and treatment.
    Asian Pacific journal of allergy and immunology, 1986, Volume: 4, Issue:2

    Topics: Autoantibodies; Child; Child, Preschool; Complement C3; Dapsone; Dermatitis Herpetiformis; Diagnosis, Differential; Drug Combinations; Female; Fluorescent Antibody Technique; Humans; Immunoglobulin A; Immunoglobulin G; Infant; Male; Prednisolone; Skin Diseases, Vesiculobullous; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1986
Dapsone, trimethoprim-sulfamethoxazole, and the acquired immunodeficiency syndrome.
    Annals of internal medicine, 1985, Volume: 103, Issue:6 ( Pt 1)

    Topics: Acquired Immunodeficiency Syndrome; Dapsone; Drug Combinations; Humans; Pneumonia, Pneumocystis; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1985
Method of testing the susceptibility of Pneumocystis carinii to antimicrobial agents in vitro.
    Antimicrobial agents and chemotherapy, 1985, Volume: 28, Issue:6

    Topics: Animals; Cells, Cultured; Dapsone; Drug Combinations; Eflornithine; Lung; Male; Ornithine; Pentamidine; Pneumocystis; Rats; Rats, Inbred Strains; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1985
[Comparative study on the effect of some clinically used sulfanilamide derivatives against toxoplasmosis in the mouse].
    Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Erste Abteilung Originale. Reihe A: Medizinische Mikrobiologie und Parasitologie, 1973, Volume: 223, Issue:2

    Topics: Aminobenzoates; Animals; Dapsone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Female; Mice; Placebos; Pyrimethamine; Structure-Activity Relationship; Sulfamerazine; Sulfamethoxazole; Sulfonamides; Time Factors; Toxoplasmosis, Animal; Trimethoprim

1973
Chemotherapeutic results in a multi-drug resistant strain of Plasmodium falciparum malaria from Vietnam.
    Military medicine, 1974, Volume: 139, Issue:3

    Topics: Adult; Alanine Transaminase; Anopheles; Antimalarials; Aspartate Aminotransferases; Dapsone; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Malaria; Male; Methylamines; Military Medicine; Phenanthrenes; Plasmodium falciparum; Pyrazines; Pyrimethamine; Quinine; Sulfanilamides; Trimethoprim; Vietnam

1974
Letter: Mycetoma.
    Tropical doctor, 1974, Volume: 4, Issue:1

    Topics: Actinomycetales Infections; Actinomycosis; Dapsone; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Immunodiffusion; Mycetoma; Streptomycin; Sudan; Sulfamethoxazole; Trimethoprim

1974
A model in vitro system to test the susceptibility of human malarial parasites to antimalarial drugs.
    The American journal of tropical medicine and hygiene, 1972, Volume: 21, Issue:4

    Topics: Amodiaquine; Antimalarials; Chloroquine; Dapsone; Drug Resistance, Microbial; Microbial Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Quinine; Trimethoprim

1972
Fundamental data, methods and goals of present research on the treatment of leprosy.
    Zeitschrift fur Tropenmedizin und Parasitologie, 1973, Volume: 24

    Topics: Animals; Animals, Laboratory; Antitubercular Agents; Clofazimine; Dapsone; Ethionamide; Humans; In Vitro Techniques; Isoniazid; Leprosy; Mice; Mycobacterium lepraemurium; Rifampin; Sulfonamides; Trimethoprim

1973
[Initial clinical results using new, experimentally developed therapeutic forms in leprosy].
    Zeitschrift fur Tropenmedizin und Parasitologie, 1973, Volume: 24

    Topics: Adolescent; Adult; Aged; Antitubercular Agents; Child; Dapsone; Drug Therapy, Combination; Ethiopia; Female; Histocytochemistry; Humans; Leprosy; Male; Middle Aged; Mycobacterium leprae; Rifampin; Skin; Sulfonamides; Thalidomide; Time Factors; Trimethoprim

1973
Considerations on the use of sulphones and sulphonamides with a pyrimidine derivative.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1974, Jun-09, Volume: 48, Issue:31

    Topics: Adult; Amodiaquine; Child; Dapsone; Drug Combinations; Drug Resistance, Microbial; Humans; Malaria; Mozambique; Plasmodium falciparum; Plasmodium malariae; Primaquine; Pyrimethamine; Sulfonamides; Trimethoprim

1974
Some pharmacological aspects of antimalarial drugs.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1974, Jun-15, Volume: 48, Issue:29

    Topics: Antimalarials; Chloroquine; Dapsone; Drug Resistance, Microbial; Humans; Malaria; Plasmodium falciparum; Plasmodium vivax; Primaquine; Proguanil; Pyrimethamine; Quinacrine; Quinine; Sulfonamides; Trimethoprim

1974
A new analogous model for the detection and evaluation of chemotherapeutic products effective in leprosy.
    Arzneimittel-Forschung, 1972, Volume: 22, Issue:8

    Topics: Aniline Compounds; Animals; Dapsone; Disease Models, Animal; Drug Combinations; Ethionamide; Humans; Isoniazid; Leprosy; Mice; Models, Biological; Mycobacterium Infections; Phenazines; Pyrazines; Rabbits; Rifampin; Sulfonamides; Trimethoprim

1972
Efficacy of diaminodiphenylsulfone and other drugs in murine Pneumocystis carinii pneumonitis.
    Antimicrobial agents and chemotherapy, 1984, Volume: 26, Issue:4

    Topics: Animals; Dapsone; Disease Models, Animal; Drug Combinations; Male; Pneumonia, Pneumocystis; Rats; Rats, Inbred Strains; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1984
Bacterial growth kinetics of Escherichia coli and mycobacteria in the presence of brodimoprim and metioprim alone and in combination with sulfamerazine and dapsone (VI).
    Chemotherapy, 1983, Volume: 29, Issue:4

    Topics: Anti-Bacterial Agents; Dapsone; Drug Synergism; Escherichia coli; Kinetics; Microbial Sensitivity Tests; Mycobacterium; Sulfamerazine; Trimethoprim

1983
[Mycetoma in northern Argentina].
    Medicina cutanea ibero-latino-americana, 1983, Volume: 11, Issue:6

    Topics: Actinomycetaceae; Adult; Aged; Argentina; Dapsone; Drug Combinations; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Mitosporic Fungi; Mycetoma; Nocardia; Nocardia Infections; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1983
Mechanism of action of the folate blocker diaminodiphenylsulfone (dapsone, DDS) studied in E. coli cell-free enzyme extracts in comparison to sulfonamides (SA).
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1980, Volume: 48, Issue:1

    Topics: 4-Aminobenzoic Acid; Dapsone; Dose-Response Relationship, Drug; Escherichia coli; Folic Acid; Folic Acid Antagonists; Kinetics; Microbial Sensitivity Tests; Mycobacterium leprae; Structure-Activity Relationship; Sulfonamides; Trimethoprim

1980
A pilot study on the efficacy of epiroprim against developmental stages of Toxoplasma gondii and Pneumocystis carinii in animal models.
    Parasitology research, 1995, Volume: 81, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Dapsone; Drug Therapy, Combination; Female; Folic Acid Antagonists; Male; Mice; Mice, Inbred Strains; Mice, Nude; Mice, SCID; Pilot Projects; Pneumocystis; Pneumocystis Infections; Pyrimethamine; Rats; Rats, Nude; Sodium Chloride; Sulfadiazine; Toxoplasma; Toxoplasmosis, Animal; Trimethoprim

1995
Relative potency of 10 drugs with anti-Pneumocystis carinii activity in an animal model.
    The Journal of infectious diseases, 1994, Volume: 170, Issue:4

    Topics: Animals; Anti-Infective Agents; Atovaquone; Azithromycin; Clarithromycin; Clindamycin; Clinical Trials as Topic; Dapsone; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, Combination; Humans; Naphthoquinones; Pentamidine; Pneumocystis Infections; Proguanil; Pyrimethamine; Rats; Sulfadoxine; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1994
Activity of epiroprim (Ro 11-8958), a dihydrofolate reductase inhibitor, alone and in combination with dapsone against Toxoplasma gondii.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:8

    Topics: Animals; Dapsone; Drug Synergism; Female; Folic Acid Antagonists; Mice; Toxoplasma; Toxoplasmosis, Animal; Trimethoprim; Uracil

1994
Major aphthous ulcers in patients with HIV disease.
    Oral surgery, oral medicine, and oral pathology, 1994, Volume: 77, Issue:2

    Topics: Adult; Biomarkers; CD4-CD8 Ratio; Dapsone; Ethnicity; Female; HIV Infections; Humans; Immune Tolerance; Male; Pennsylvania; Prevalence; Prospective Studies; Risk Factors; Smoking; Stomatitis, Aphthous; Sulfamethoxazole; Trimethoprim

1994
Synergistic combinations of Ro 11-8958 and other dihydrofolate reductase inhibitors with sulfamethoxazole and dapsone for therapy of experimental pneumocystosis.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:7

    Topics: AIDS-Related Opportunistic Infections; Animals; Dapsone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Folic Acid Antagonists; Immunosuppression Therapy; Male; Pneumonia, Pneumocystis; Rats; Rats, Sprague-Dawley; Sulfamethoxazole; Trimethoprim

1993
Population-based estimates of antiretroviral therapy and anti-Pneumocystis prophylaxis in San Francisco: 1991.
    Journal of acquired immune deficiency syndromes, 1993, Volume: 6, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antiviral Agents; Cohort Studies; Dapsone; Didanosine; Drug Combinations; Follow-Up Studies; HIV Infections; Humans; Male; Pentamidine; Pneumonia, Pneumocystis; San Francisco; Sulfamethizole; Trimethoprim; Zalcitabine; Zidovudine

1993
Efficacy of ganciclovir in combination with other antimicrobial agents against cytomegalovirus in vitro and in vivo.
    Antiviral research, 1993, Volume: 20, Issue:1

    Topics: Amphotericin B; Animals; Antifungal Agents; Antiviral Agents; Cells, Cultured; Cytomegalovirus Infections; Dapsone; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Ganciclovir; Humans; Ketoconazole; Mice; Mice, Inbred Strains; Microbial Sensitivity Tests; Species Specificity; Sulfamethoxazole; Survival Analysis; Trimethoprim; Viral Plaque Assay

1993
Predictive value of bronchoalveolar lavage in excluding a diagnosis of Pneumocystis carinii pneumonia during prophylaxis with aerosolized pentamidine.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1993, Volume: 16, Issue:4

    Topics: Administration, Intranasal; Adult; Aerosols; AIDS-Related Opportunistic Infections; Bronchoalveolar Lavage Fluid; Dapsone; Female; Follow-Up Studies; Humans; L-Lactate Dehydrogenase; Male; Middle Aged; Pentamidine; Pneumocystis; Pneumonia, Pneumocystis; Predictive Value of Tests; Prospective Studies; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1993
Efficacy of epiroprim (Ro11-8958), a new dihydrofolate reductase inhibitor, in the treatment of acute Toxoplasma infection in mice.
    The American journal of tropical medicine and hygiene, 1996, Volume: 54, Issue:3

    Topics: Acute Disease; Administration, Oral; Animals; Anti-Infective Agents; Antiprotozoal Agents; Dapsone; Drug Therapy, Combination; Folic Acid Antagonists; Half-Life; Humans; Injections, Intraperitoneal; Injections, Subcutaneous; Mice; Mice, Inbred BALB C; Sulfadiazine; Toxoplasmosis, Animal; Trimethoprim

1996
Antibacterial activities of epiroprim, a new dihydrofolate reductase inhibitor, alone and in combination with dapsone.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:6

    Topics: Animals; Dapsone; Drug Combinations; Folic Acid Antagonists; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Mice; Microbial Sensitivity Tests; Sepsis; Trimethoprim

1996
Combination of PS-15, epiroprim, or pyrimethamine with dapsone in prophylaxis of Toxoplasma gondii and Pneumocystis carinii dual infection in a rat model.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:9

    Topics: Animals; Anti-Bacterial Agents; Antiprotozoal Agents; Dapsone; Drug Therapy, Combination; Folic Acid Antagonists; Immunosuppression Therapy; Pneumocystis Infections; Proguanil; Pyrimethamine; Rats; Rats, Wistar; Tetrahydrofolate Dehydrogenase; Toxoplasma; Toxoplasmosis, Animal; Trimethoprim

1996
Pneumocystis carinii infection of the conjunctiva in a patient with acquired immune deficiency syndrome.
    Ophthalmology, 1997, Volume: 104, Issue:11

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Conjunctiva; Conjunctival Diseases; Dapsone; Eye Infections, Fungal; Fatal Outcome; Humans; Male; Pneumocystis; Pneumocystis Infections; Trimethoprim

1997
In vitro activity of epiroprim, a dihydrofolate reductase inhibitor, singly and in combination with brodimoprim and dapsone, against Mycobacterium leprae.
    International journal of antimicrobial agents, 1999, Volume: 12, Issue:4

    Topics: Cell-Free System; Dapsone; Folic Acid Antagonists; Leprostatic Agents; Microbial Sensitivity Tests; Mycobacterium leprae; Trimethoprim

1999
Antimicrobial activities of dihydrofolate reductase inhibitors, used singly or in combination with dapsone, against Mycobacterium ulcerans.
    The Journal of antimicrobial chemotherapy, 2001, Volume: 47, Issue:1

    Topics: Anti-Bacterial Agents; Dapsone; Drug Therapy, Combination; Folic Acid Antagonists; Humans; Microbial Sensitivity Tests; Mycobacterium Infections, Nontuberculous; Mycobacterium ulcerans; Tetrahydrofolate Dehydrogenase; Trimethoprim

2001
Effect of mutations in Pneumocystis carinii dihydropteroate synthase gene on outcome of P carinii pneumonia in patients with HIV-1: a prospective study.
    Lancet (London, England), 2001, Aug-18, Volume: 358, Issue:9281

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Dapsone; Dihydropteroate Synthase; Drug Resistance, Microbial; Genotype; HIV-1; Humans; Male; Middle Aged; Mutation; Pneumocystis; Pneumonia, Pneumocystis; Prognosis; Prospective Studies; Survival Analysis; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

2001
In vivo activity of epiroprim, a dihydrofolate reductase inhibitor, singly and in combination with dapsone, against Mycobacterium leprae.
    International journal of antimicrobial agents, 2002, Volume: 19, Issue:1

    Topics: Administration, Oral; Animals; Armadillos; Dapsone; Drug Synergism; Female; Folic Acid Antagonists; Leprostatic Agents; Mice; Mice, Inbred BALB C; Mycobacterium leprae; Trimethoprim

2002
A confirmatory method for the simultaneous extraction, separation, identification and quantification of Tetracycline, Sulphonamide, Trimethoprim and Dapsone residues in muscle by ultra-high-performance liquid chromatography-tandem mass spectrometry accord
    Journal of chromatography. A, 2009, Nov-13, Volume: 1216, Issue:46

    Topics: Animals; Anti-Bacterial Agents; Cattle; Chromatography, High Pressure Liquid; Dapsone; Drug Residues; Muscles; Poultry; Sheep; Sulfonamides; Tandem Mass Spectrometry; Tetracycline; Trimethoprim

2009
Prevalence of G6PD deficiency in a large cohort of HIV-infected patients.
    The Journal of infection, 2010, Volume: 61, Issue:5

    Topics: Adult; Aged; Anemia, Hemolytic; Anti-Infective Agents; Black or African American; Cohort Studies; Dapsone; Drug Combinations; Female; Glucosephosphate Dehydrogenase; Glucosephosphate Dehydrogenase Deficiency; Hispanic or Latino; HIV Infections; Humans; Male; Middle Aged; Prevalence; Sulfamethizole; Texas; Trimethoprim; Urban Population; White People; Young Adult

2010
Development of a liquid chromatography–tandem mass spectrometry method for the determination of sulfonamides, trimethoprim and dapsone in honey and validation according to Commission Decision 2002/657/EC for banned compounds [corrected].
    Talanta, 2012, Aug-15, Volume: 97

    Topics: Chromatography, Liquid; Dapsone; Food Contamination; Guidelines as Topic; Honey; Limit of Detection; Sulfonamides; Tandem Mass Spectrometry; Trimethoprim; Uncertainty

2012
Feasibility of amlodipine besylate, chloroquine phosphate, dapsone, phenytoin, pyridoxine hydrochloride, sulfadiazine, sulfasalazine, tetracycline hydrochloride, trimethoprim and zonisamide in SyrSpend(®) SF PH4 oral suspensions.
    Journal of pharmaceutical and biomedical analysis, 2016, Jan-25, Volume: 118

    Topics: Administration, Oral; Amlodipine; Chloroquine; Chromatography, High Pressure Liquid; Dapsone; Drug Stability; Drug Storage; Feasibility Studies; Hydrogen-Ion Concentration; Isoxazoles; Phenytoin; Pyridoxine; Sulfadiazine; Sulfasalazine; Suspensions; Tetracycline; Trimethoprim; Zonisamide

2016
Validation of a liquid chromatography-tandem mass spectrometry method for the simultaneous determination of sulfonamides, trimethoprim and dapsone in muscle, egg, milk and honey.
    Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2016, Volume: 33, Issue:4

    Topics: Animals; Chromatography, Liquid; Dapsone; Eggs; Honey; Milk; Muscles; Reproducibility of Results; Sulfonamides; Tandem Mass Spectrometry; Trimethoprim

2016